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3T3 murine embryonic fibroblasts are used as feeder layers to support the proliferative potential of human primary keratinocytes during in vitro expansion for cell and gene therapy applications. To identify signals mediating this function, we analyzed fibroblast protein content using mass spectrometry. We compared the proteome of lethally irradiated fibroblasts used as feeder layers at two time points: 24 hours and 4 days post-seeding. Our findings highlight differences in extracellular matrix ...
Programme: Independent Projects
Public web page: Not specified
The New Medicines for Trypanosomatidic Infections - NMTrypI project aimed at obtaining new candidate drugs against Trypanosomatidic infections with appropriate efficiency from the lead phase to the final preclinical phase that are more accessible to patients.
Programme: Drug development for neglected parasitic diseases
Public web page: https://fp7-nmtrypi.eu/
Start date: 1st Feb 2014
End date: 31st Jan 2017
Public web page: Not specified
This folder contains the Standard Operating Procedures (SOPs) of the Drug Discovery and Biotechnology
Programme: Independent Projects
Public web page: Not specified
Programme: Cancer drug discovery preclinical research
Public web page: Not specified
Programme: Cancer drug discovery preclinical research
Public web page: Not specified