Antimicobacterium, Antiparasitic and in vitro toxicity for Ty-Box library
SEEK ID: https://fairdomhub.org/assays/1427
Experimental Assay
Projects: NMTrypI - New Medicines for Trypanosomatidic Infections
Investigation: Phenotypic and machine learning approaches for hit to lead optimization of broad spectrum non-toxic antiparasitic agents
Study: Ty-Box chemical characterization, properties and biological evaluation
Assay position:
Assay type: Experimental Assay Type
Technology type: Technology Type
Organisms: No organisms
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Created: 26th Mar 2021 at 20:56
Last updated: 17th May 2021 at 14:30
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Projects: NMTrypI - New Medicines for Trypanosomatidic Infections
Web page: https://cordis.europa.eu/programme/id/FP7_HEALTH.2013.2.3.4-2
The New Medicines for Trypanosomatidic Infections - NMTrypI project aimed at obtaining new candidate drugs against Trypanosomatidic infections with appropriate efficiency from the lead phase to the final preclinical phase that are more accessible to patients.
Programme: Drug development for neglected parasitic diseases
Public web page: https://fp7-nmtrypi.eu/
Start date: 1st Feb 2014
End date: 31st Jan 2017
Submitter: Pasquale Linciano
Studies: Chemical characterization, and biological evaluation of the SECONDARY HITS, Ty-Box chemical characterization, properties and biological evaluation
Assays: Antimicobacterium, Antiparasitic and in vitro toxicity for Ty-Box library, Biological characterization for Secondary Hits, Secondary Hits Characterization, Ty-Box library characterization
Chemical structures, physicochemical properties and biological results for the compounds of the Ty-Box library
In vitro early toxicity profiles (all experiments were performed in triplicate, IC50 in μM) for the reference drugs Pentamidine (PEN), Benzidazole (BZD), Amphotericin B (AmB) and Miltefosine (MIL).
