Creation of homology models of various tubulins from dinitroaniline-sensitive and -resistant species, and a comparative analysis of their electrostatic potential grids overall and in putative binding site regions using PIPSA (Protein Interaction Property Similarity Analysis).
Submitter: Ina Poehner
Biological problem addressed: Model Analysis Type
Investigation: Antiparasitic dinitroaniline-ether phospholipid...
Trypanosoma cruzi multimeric alpha-tubulin protein receptor for docking studies, generated by alignment of two identical models of T. cruzi alpha-tubulin on template 5ubq alpha-tubulin chains of two neighboring protofilaments (A, C).
Creators: Ina Poehner, Rebecca Wade
Submitter: Ina Poehner
DownloadTrypanosoma brucei multimeric alpha-tubulin protein receptor for docking studies, generated by alignment of two identical models of T. brucei alpha-tubulin on template 5ubq alpha-tubulin chains of two neighboring protofilaments (A, C).
Creators: Ina Poehner, Rebecca Wade
Submitter: Ina Poehner
Leishmania infantum multimeric alpha-tubulin protein receptor for docking studies, generated by alignment of two identical models of L. infantum alpha-tubulin on template 5ubq alpha-tubulin chains of two neighboring protofilaments (A, C).
Creators: Ina Poehner, Rebecca Wade
Submitter: Ina Poehner
Leishmania donovani multimeric alpha-tubulin protein receptor for docking studies, generated by alignment of two identical models of L. donovani alpha-tubulin on template 5ubq alpha-tubulin chains of two neighboring protofilaments (A, C).
Creators: Ina Poehner, Rebecca Wade
Submitter: Ina Poehner
Collected PDB-files of homology models of alpha-tubulin, all based on T. thermophila tubulin PDB-ID 5ubq, chain A:
Includes models of the following dinitroaniline herbicide sensitive species (UniProt ID in brackets):
- C. reinhardtii (P09204)
- E. indica (O22347)
- L. donovani (I3W8N6)
- L. infantum (E9AGJ8)
- L. major (Q4QGC5)
- P. falciparum (P14642)
- S. viridis (Q65C79)
- T. brucei (Q4GYY5)
- T. cruzi (Q27352)
- T. gondii (P10873)
- Z. mays (P14640)
Includes models of the following dinitroaniline ...
Creators: Ina Poehner, Rebecca Wade
Submitter: Ina Poehner
SOP for protein preparation steps performed for alpha-tubulin homology models (hydrogen addition, hydrogen bonding network optimization and energy minimization)
Creators: Ina Poehner, Rebecca Wade
Submitter: Ina Poehner
General SOP for alpha-tubulin homology model building
Creators: Ina Poehner, Rebecca Wade
Submitter: Ina Poehner
