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2 Assays visible to you, out of a total of 2

Model simulations of HSD11B1/AKR1C3 incubation and cortisone and 11KA4 inversion during CBX inhibition

Steroid biosynthesis

HSD11B1 was inhibitied by CBX and the effect of the inhibition on cortisone and 11KA4 conversion was simulated. The model was coded in Mathematica and the f=manuscript figures 3 A,B,C,D,E anbd F are presented in the notebook.

Submitter: Jacky Snoep

Biological problem addressed: Model Analysis Type

Investigation: Effect of 11BHSD inhibition on 11-ketotestoster...

Study: CBX inhibition of HSD11B1 and effect on HSD11B1...

Organisms: No organisms

Models: Model simulations of HSD11B1/AKR1C3 incubation ...

SOPs: No SOPs

Data files: No Data files

Snapshots: No snapshots

Created: 19th Feb 2024 at 13:49, Last updated: 17th Mar 2024 at 08:56

Experimental data for HSD11B1/AKR1C3 incubation with CBX inhibition

Steroid biosynthesis

HSD11B1 was inhibited by CBX and conversion of cortisone and 11KA4 by HSD11B1 and AKR1C3 was followed over time.

Submitter: Jacky Snoep

Assay type: Experimental Assay Type

Technology type: Technology Type