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Kay et al. 2026, DNA Repair 166 (2026) 103955 (DOI: 10.1016/j.dnarep.2026.103955; PMID: 42566817). A study of how sex and the Aag base-excision-repair gene modulate NDMA-induced liver damage, mutagenesis and tumourigenesis in mice. Reach out to Jenny Kay (kay@silentspring.org) with any questions.
**Abstract: ** N-Nitrosodimethylamine (NDMA) is present in food, water, and drugs and is considered a probable human carcinogen by the International Agency for Research on Cancer. The mechanism of ...
Submitter: Juanita Pardo Sanchez
Investigation: MIT SRP
Assays: Chemical Challenge, Cleaved caspase-3 staining and analysis, Flow Cytometry, Flow Cytometry Analysis, GPT Assay, HistoPathology Analysis, Imaging, RaDR Image Machine Learning Analysis, Tissue Collection, Tissue Imaging, Tissue Sectioning, γH2AX staining and analysis
