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AUC values and parameters of the corresponding curves for each replicate of each drug and condition

Working Group Nicole Radde, SteaPKMod

The parameters A and B were estimated for the function f(x)=x⋅e^(B-Ax) and the AUC was calculated for the decay phase only. For OH-Midazolam the fourth replicate in the 2 weeks condition has an outlier in the measurement after six hours (more than 2SD above the mean of this condition) and was omitted for the AUC calculation as this could not be fitted to an exponential decay.

Creators: None

Submitter: Sebastian Höpfl

Investigations: 2 hidden items

Studies: Periportal steatosis in mice affects distinct p... and 1 hidden item

Assays: Bayesian uncertainty quantification, Bayesian uncertainty quantification

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Created: 22nd Jul 2022 at 08:06, Last updated: 9th Dec 2022 at 06:08

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