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Submitter
Ettore Murabito1
Programme
SysMO1
Organism
Lactococcus lactis1
Model type
Ordinary differential equations (ODE)1
Model format
Copasi1
Recommended environment
Copasi1
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The principles of Stealthy Engineering (Adamczyk et al.: Biotechnology Journal 2012; 7(7):877-83) are illustrated in this model by emulating a cross engineering intervention between L. lactis and S. cerevisiae.
The case study consists of replacing the native glucose uptake system of L. lactis with that native to the yeast S. cerevisiae. A modified version of Hoefnagel et al.’s model of L. lacrtis’ central metabolism was used as starting point. The total functional replacement of the PTS with the ...
Creators: Malgorzata Adamczyk, Hans V. Westerhoff, Ettore Murabito
Submitter: Ettore Murabito
Model type: Ordinary differential equations (ODE)
Model format: Copasi
Environment: Copasi
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