Models

Mathematica notebook for the parameterisation of the G3PDH rate equation based on SEEK linked experimental data.

Mathematica notebook for the parameterisation of the ALD rate equation based on SEEK linked experimental data.

Mathematica notebook for the ATPase reaction.

Mathematica notebook for the parameterisation of the ENO rate equation based on SEEK linked experimental data.

Mathematica notebook for the lactate transport rate equation, based on literature data.

Mathematica notebook for the glycerol transport rate equation.

Mathematica notebook for the parameterisation of the GAPDH rate equation based on SEEK linked experimental data.

Mathematica notebook for the parameterisation of the PGI rate equation based on SEEK linked experimental data.

Mathematica notebook for the parameterisation of the LDH rate equation based on SEEK linked experimental data.

Mathematica notebook for the parameterisation of the TPI rate equation based on SEEK linked experimental data.

Mathematica notebook for the parameterisation of the PFK rate equation based on SEEK linked experimental data.

Mathematica notebook for the pyruvate transport rate equation, based on literature data.

Mathematica notebook for the parameterisation of the PGK rate equation based on SEEK linked experimental data.

Mathematica notebook for the parameterisation of the PK rate equation based on the experimental SEEK data set

Mathematica notebook for the parameterisation of the PGM rate equation based on SEEK linked experimental data.

Mathematical model for HK kinetics, GLC and ATP saturation, and inhibition with G6P and ADP.

Using optical tweezers to position yeast cells in a microfluidic chamber, we were able to observe sustained oscillations in individual isolated cells. Using a detailed kinetic model for the cellular reactions, we simulated the heterogeneity in the response of the individual cells, assuming small differences in a single internal parameter. By operating at two different flow rates per experiment, we observe four of categories of cell behaviour. The present model (gustavsson4) predicts the steady-state ...