Silke Meiners
SEEK ID: https://fairdomhub.org/people/2559
Location:
Germany
https://orcid.org/0000-0003-3678-7995Expertise: Not specified
Tools: Not specified
Their tagsRelated items
The FZB is the lung research center of the Leibniz Association and is therefore committed to the motto “theoria cum praxi”.
The FZB sees its scientific and socio-political task in basic, disease- and patient-oriented lung research and training in this field. The field of research includes chronic inflammatory diseases of the lung of infectious and non-infectious environmental and behavioral origin. Research focuses on tuberculosis, infections with non-tuberculous mycobacteria and other bacterial ...
Projects: Group Data Science, Group Microbial Interface Biology, Core Facility Fluorescence Cytometry, Targeting the immunoproteasome: Analyzing the biological effects of specific versus pan inhibition, Macrophage and neutrophil redox proteome in infection with Mycobacterium tuberculosis, Methylation differences during respiratory infection, Lipid droplet formation and dynamics in murine macrophages, OMICS of vascular smooth muscle cells under oxidative stress, Lung health related PGS and GWAS, Archaean stimulation of human primary PBMCs and PBMCs monocytes
Web page: https://fz-borstel.de
Background: The immunoproteasome is expressed constitutively in immune cells alongside standard proteasomes and forms multiple mixed types of proteasome complexes. These mixed 20S proteasomes may have distinct proteolytic activities depending on their subunit composition and may thereby regulate immune cell function. Using site-specific versus pan-inhibitors of the immunoproteasome, we here aim to dissect the biological functions of the three active sites of the immunoproteasome for monocyte cell ...
Programme: Research Center Borstel
Public web page: Not specified
ROR ID: Not specified
Department: Not specified
Country: Germany
City: Borstel
Web page: https://fz-borstel.de
