Adlung et al (2017) Molecular Systems Biology
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Protein abundance of AKT and ERK pathway components governs cell-type- specific regulation of proliferation
SEEK ID: https://fairdomhub.org/investigations/121
Projects: Molecular Systems Biology
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Created: 11th Jan 2017 at 10:26
Last updated: 11th Jan 2017 at 11:43
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Projects: PSYSMO, MOSES, SysMO DB, SysMO-LAB, SulfoSys, SulfoSys - Biotec, Whole body modelling of glucose metabolism in malaria patients, FAIRDOM, Molecular Systems Biology, COMBINE Multicellular Modelling, HOTSOLUTE, Steroid biosynthesis, Yeast glycolytic oscillations, Computational pathway design for biotechnological applications, SCyCode The Autotrophy-Heterotrophy Switch in Cyanobacteria: Coherent Decision-Making at Multiple Regulatory Layers, Project Coordination, WP 3: Drug release kinetics study, Glucose metabolism in cancer cell lines
Institutions: Manchester Centre for Integrative Systems Biology, University of Manchester, University of Stellenbosch, University of Manchester - Department of Computer Science, Stellenbosch University
https://orcid.org/0000-0003-2633-0537
This programme is used to store published data files that are not available in other FAIRDOM projects. We specifically store information for journals that we collaborate with for technical curation of mathematical models. These files are used in COMBINE archives to reproduce journal figures.
Projects: Molecular Systems Biology
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The Molecular Systems Biology project holds information for reproducing simulation figures in the journal. This can include experimental data files, model files and manuscript information.
Programme: Journals
Public web page: http://msb.embopress.org
Growth-factor deprived mCFU-E cells (5x106 cells per condition) and BaF3-EpoR cells (1x107 cells per condition) were stimulated with different Epo doses and absolute concentrations were determined for pEpoR (B), pAKT (C), ppERK (D). The scale for pS6 (E) was estimated in arbitrary units. GTP-Ras (F) and ppERK were determined upon stimulation with indicated, color-coded Epo doses. pEpoR was analyzed by immunoprecipitation followed by immunoblotting, GTP-Ras was analyzed after pulldown using a ...
Submitter: Dawie van Niekerk
Assay type: Experimental Assay Type
Technology type: Technology Type
Investigation: Adlung et al (2017) Molecular Systems Biology
Submitter: Dawie van Niekerk
Biological problem addressed: Model Analysis Type
Investigation: Adlung et al (2017) Molecular Systems Biology
See Figure 2 caption.
Creators: Dawie van Niekerk, Jacky Snoep
Submitter: Dawie van Niekerk
See Figure 2 caption.
Creators: Dawie van Niekerk, Jacky Snoep
Submitter: Dawie van Niekerk
Creators: Dawie van Niekerk, Jacky Snoep
Submitter: Dawie van Niekerk
See Figure 2 caption.
Creators: Dawie van Niekerk, Jacky Snoep
Submitter: Dawie van Niekerk
See Figure 2 caption.
Creators: Dawie van Niekerk, Jacky Snoep
Submitter: Dawie van Niekerk
See Figure 2 caption.
Creators: Dawie van Niekerk, Jacky Snoep
Submitter: Dawie van Niekerk
See Figure 2 caption
Creators: Dawie van Niekerk, Jacky Snoep
Submitter: Dawie van Niekerk
See Figure 2 caption.
Creators: Dawie van Niekerk, Jacky Snoep
Submitter: Dawie van Niekerk
Creators: Dawie van Niekerk, Jacky Snoep
Submitter: Dawie van Niekerk
Model type: Ordinary differential equations (ODE)
Model format: SBML
Environment: Not specified
Creators: Dawie van Niekerk, Jacky Snoep
Submitter: Dawie van Niekerk
Model type: Ordinary differential equations (ODE)
Model format: SBML
Environment: Not specified
Abstract (Expand)
Authors: L. Adlung, S. Kar, M. C. Wagner, B. She, S. Chakraborty, J. Bao, S. Lattermann, M. Boerries, H. Busch, P. Wuchter, A. D. Ho, J. Timmer, M. Schilling, T. Hofer, U. Klingmuller
Date Published: 24th Jan 2017
Publication Type: Journal
