Log2 fold changes after drug treatment/serum stimulation of MAPK and AKT pathway nodes
egf hgf nrg1 plx plx + egf plx + hgf plx + nrg1 mek mek + egf mek + hgf mek + nrg1 erk erk + egf erk + hgf erk + nrg1 akt akt + egf akt + hgf akt + nrg1 pi3k pi3k + egf pi3k + hgf pi3k + nrg1 EGFR 0.39733549754538494 0.5731853329448026 0.6424479953819163 0.5004289905094883 0.5731853329448026 0.39733549754538494 0.6197279188818328 0.28630418515664097 0.5004289905094883 0.6868421147403698 0.28630418515664097 0.16600995143892933 0.4498029174395205 0.5731853329448026 0.8519013610108661 0.39733549754538494 0.423807708906576 0.2274104961030724 0.7085371858396886 0.5004289905094883 0.6868421147403698 0.4498029174395205 0.39733549754538494 MEK 0.4209617398311108 0.6382157135103439 0.774128408872364 -5.997107087378588 -5.924957301622753 -5.790656209911162 -5.69754680551968 1.2667940622727378 1.1853509344670414 1.1848415082467452 1.4083617030514772 -0.2285834247097318 0.4373072967772899 0.7686996346739283 0.9666041464728917 0.6344897428419706 0.7818966556502057 0.5966910117065561 1.0049145054426867 0.5511714424139054 0.5586618830077064 0.20583297129168704 0.5384673863804045 ERK 0.5235619560570128 0.5849625007211562 0.8328900141647416 -0.5405683813627028 -0.4764380439429871 -0.2995602818589078 -0.04580368961312479 -0.3561438102252753 -0.19264507794239588 -0.14201900487242788 0.0 -0.4150374992788438 -0.3561438102252753 -0.24511249783653147 0.16992500144231237 0.4918530963296747 0.28540221886224837 0.42626475470209796 0.7279204545631992 0.32192809488736235 0.6438561897747247 0.45943161863729726 0.42626475470209796 P90RSK 0.3286227474613706 0.802553935793783 0.9660526680766622 -0.2168113890731482 -0.2563397532597855 0.21759143507262685 0.48062584090642063 -0.42626475470209796 0.15869774601905823 0.5044725828607884 0.15869774601905823 -0.3388019134517586 -0.2563397532597855 -0.03394733192333771 0.7234823648025842 -0.2969817377571315 -0.0687127500840142 -0.10433665981473561 0.15869774601905823 0.15869774601905823 0.0972972013549148 -0.1783372412585124 -0.1783372412585124 GSK3AB 1.2812861103900164 2.0033357125632563 2.1246957474493144 0.294961047287093 0.7086368711077118 1.6092471528445833 2.1978537450230196 0.7127180479195289 1.361456459074 1.756865151603911 2.3562481680712386 -0.11826288161981974 1.0524674198941355 1.604862058158861 1.9899463353360771 0.5397332467281585 0.3325753390868709 0.7086368711077118 1.0099840885726221 0.6288167903105837 0.6629650127224292 0.5305147166987798 0.7329525316595827 RPS6 0.8450253400236591 1.4150374992788437 1.645991934118716 -0.7548875021634687 -0.23132554610645567 0.07800251200127316 0.3325753390868709 -0.46948528330122025 0.026472211361191177 0.784271308944563 0.9175378398080271 -0.3973354975453848 0.0 -0.05444778402237646 1.0524674198941355 -0.05444778402237646 -0.11103131238874384 -0.02696704760026932 0.5670405927238937 -0.16992500144231246 -0.05444778402237646 -0.16992500144231246 -0.02696704760026932 PI3K 0.22239242133644802 0.41503749927884376 0.6880559936852598 -0.16992500144231246 0.0 0.15200309344505006 0.3536369546147004 0.0 0.289506617194985 0.07800251200127316 0.41503749927884376 0.0 0.22239242133644802 0.15200309344505006 0.6374299206152918 -0.16992500144231246 0.07800251200127316 -0.08246216019197299 0.41503749927884376 0.07800251200127316 0.41503749927884376 -0.08246216019197299 0.0 AKT 2.876193798385602 5.148677267738273 7.146803115987985 0.36678233067162275 2.351985328743542 5.32382513005996 7.072873035438051 1.3219280948873624 4.516944077292505 5.726487076361941 7.142510176116952 0.03747470541866296 1.9418970454364317 4.712074418624495 6.940043078540613 -0.24792751344358557 -0.1604646721932461 -0.2937312030567103 0.21150410519371182 -0.34103691783506696 0.0 0.0 -0.3899465183160133 MTOR 1.0297473433940518 1.5443205162238103 1.34577483684173 0.45943161863729726 0.5025003405291834 1.369233809665719 1.4150374992788437 0.5849625007211562 0.7369655941662062 1.2976805486406853 1.6911619045530812 -0.12553088208385899 0.5647846187835259 1.1429579538420431 1.1699250014423124 0.5443205162238102 0.5443205162238102 0.5443205162238102 0.7369655941662062 0.48112668973661615 0.7725895038969275 0.41503749927884376 0.5235619560570128 JNK 1.1375035237499351 1.3219280948873624 1.632268215499513 0.48542682717024166 0.632268215499513 0.925999418556223 1.070389327891398 0.5849625007211562 0.765534746362977 1.1043366598147355 0.5360529002402097 0.32192809488736235 0.5360529002402097 0.8073549220576041 1.4854268271702418 0.6780719051126377 0.6780719051126377 0.5360529002402097 0.8875252707415875 0.6780719051126377 0.8073549220576041 0.6780719051126377 0.43295940727610627 CJUN 0.33560303178443884 0.5849625007211562 1.0170735133589415 -0.22239242133644802 -0.2630344058337938 -0.03476541816067664 0.06711419585853703 -0.22239242133644802 -0.07038932789139803 0.06711419585853703 0.19264507794239583 -0.1443899093351748 -0.22239242133644802 0.13124453327825272 0.36257007938470837 -0.07038932789139803 -0.03476541816067664 -0.03476541816067664 0.13124453327825272 -0.1069152039165119 0.0 -0.18286405714981055 -0.1069152039165119 P38 0.0752881273042372 0.301169534720565 0.301169534720565 -0.13492958008610853 -0.1069152039165119 0.0 -0.1069152039165119 -0.16349873228287934 0.0 -0.05246741989413554 0.14684138832927118 -0.13492958008610853 0.05062607306996814 0.12338241550528205 0.32192809488736235 0.025535092107137478 -0.1069152039165119 -0.05246741989413554 0.16992500144231237 0.0752881273042372 0.12338241550528205 0.09953567355091437 -0.025995208532944573 IKBA 0.3410369178350669 0.717600269299275 1.078002512001273 0.12285674778553338 0.18057224564182084 0.20858662181141732 0.41503749927884376 -0.0324214776923775 0.2360673582335245 0.3155018257279294 0.15200309344505006 0.2360673582335245 0.20858662181141732 0.3661278987978975 0.7369655941662062 0.09310940439148145 0.06273575534796275 -0.24392558288608923 0.15200309344505006 0.20858662181141732 0.2630344058337938 0.03170885972733805 0.15200309344505006 P53 0.41503749927884376 0.9296106721086019 1.0 0.19264507794239583 0.30812229536233193 0.4656635723488118 0.5145731728297582 0.06711419585853703 0.2515387669959644 0.4656635723488118 0.06711419585853703 0.2515387669959644 0.4656635723488118 0.6520766965796931 0.777607578663552 0.06711419585853703 0.19264507794239583 0.0 0.30812229536233193 0.19264507794239583 0.36257007938470837 0.2515387669959644 0.2515387669959644 SMAD2 0.3590810933048283 0.5639008851933265 0.9358696625802845 -0.06413033741971558 -0.03170885972733814 0.14886338591448275 0.30932805810772873 -0.03170885972733814 0.2313255461064558 0.2313255461064558 0.3344190390705593 -0.16600995143892924 0.14886338591448275 0.20435849850618631 0.4988058569714417 0.12029423371771175 0.06140054466414327 -0.20163386116965057 0.28379296600059134 -0.06413033741971558 0.17687776208407918 -0.03170885972733814 0.12029423371771175
Creators and SubmitterCreator
Submitter
Views: 2811 Downloads: 181
Created: 9th Sep 2019 at 12:02
Last updated: 14th Jan 2020 at 15:03
TagsThis item has not yet been tagged.
AttributionsNone
Version History
Version 1 (earliest) Created 9th Sep 2019 at 12:02 by Evert Bosdriesz
No revision comments
Download
Explore
https://orcid.org/0000-0002-8788-9548