LF_deseq_comparison

Version 2

Geneid	baseMean	log2FoldChange	lfcSE	stat	pvalue	padj	Length	Product	Manually_assigned_category	KO	Class_from_Pwy_association	Class_from_KO_Brite	Subclass_from_KO_Brite	COG	COG_category
LFTS_00959	491.999251990747	4.7837514867402	0.174907432457904	27.3501898662398	1.07429557401125e-164	2.67069879699198e-161	447	tRNA 2-thiouridine synthesizing protein D	NA	K07235	 Folding, sorting and degradation	              Folding, sorting and degradation	               04122 Sulfur relay system	COG1553	P
LFTS_00921	759.617776242733	-4.5527888592743	0.200465920547439	-22.7110366033358	3.48524027968605e-114	4.33215366764976e-111	1443	Outer membrane protein TolC	NA	K15725	NA	              Signal transduction	               02020 Two-component system	COG1538	M
LFTS_00427	649.478000850295	4.23082031623869	0.189130114482997	22.3698924298967	7.73229623751629e-111	6.40749614882183e-108	1734	dissimilatory adenylylsulfate reductase alpha subunit precursor	NA	K00394	 Energy metabolism	              Energy metabolism	               00920 Sulfur metabolism	NA	
LFTS_00960	218.750421060272	4.60497840986889	0.218787537387433	21.0477180960921	2.39957677875343e-98	1.49133696799526e-95	327	Sulfur relay (sulfurtransferase) complex TusBCD TusD component%2C DsrE family	NA	K06039	NA	              Metabolism of cofactors and vitamins	               00860 Porphyrin and chlorophyll metabolism	COG1553	P
LFTS_02336	2435.27271366882	-2.59716427415177	0.131838592162596	-19.6995753030243	2.17436260786922e-86	1.08109308863258e-83	828	flagellin	Motility	K02406	 Cell motility; Environmental adaptation; Signal transduction; Infectious diseases; Immune system	              Signal transduction	               02020 Two-component system	COG1344	N
LFTS_01396	5051.43123361374	-3.59816837919915	0.190627263688588	-18.8754132518903	1.81697084943719e-79	7.52831588616811e-77	1383	cytochrome c oxidase cbb3-type subunit 1	Cytochrome cbb3 oxidase	K00404	 Energy metabolism; Signal transduction	              Energy metabolism	               00190 Oxidative phosphorylation	COG3278	C
LFTS_00919	993.338851348639	-3.35246276454037	0.178259682682836	-18.8066236519963	6.66498457802371e-79	2.36702166585242e-76	3183	Cu(I)/Ag(I) efflux system membrane protein CusA/SilA	Copper/silver resistance	K07787	 Signal transduction	              Signal transduction	               02020 Two-component system	COG3696	P
LFTS_00956	200.63660973393	3.89294412052327	0.215798333565394	18.0397320785778	9.50033875074283e-73	2.95223026679334e-70	411	Peroxiredoxin family protein	Oxidative stress response	K07092	NA	              Folding, sorting and degradation	               04122 Sulfur relay system	COG2044	R
LFTS_00917	453.642930318274	-3.36033718101686	0.200862733213261	-16.7295203408843	7.98789771862693e-63	2.20643485872295e-60	390	hypothetical protein	NA	K03546	NA	              Membrane transport	               02010 ABC transporters	COG0419	L
LFTS_00958	183.639401313004	3.87981886406105	0.233186237457009	16.6382840873118	3.6801340560863e-62	9.14881326343055e-60	387	Sulfur relay (sulfurtransferase) complex TusC component%2C DsrF/TusC family	NA	K06039	NA	              Folding, sorting and degradation	               04122 Sulfur relay system	COG1553	P
LFTS_00220	368.993797238116	-3.3565931328476	0.211932985841213	-15.8379929368922	1.70166034808801e-56	3.84575238667891e-54	1182	flagellar biosynthesis protein FlhF	Motility	K02404	NA	              Signal transduction	               02020 Two-component system	COG1419	N
LFTS_00428	178.623068654873	3.97033142876654	0.260536410977861	15.2390654874874	1.94634274591478e-52	4.03217338862011e-50	345	adenylylsulfate reductase subunit B	NA	K00395	 Energy metabolism	              Energy metabolism	               00920 Sulfur metabolism	NA	
LFTS_00221	248.607626533693	-3.62459742365615	0.242707558886562	-14.9340112861925	1.97988918511933e-50	3.78615731862051e-48	879	flagellar biosynthesis protein FlhG	Motility	K04562	NA	              Signal transduction	               02020 Two-component system	COG0455	DN
LFTS_02037	662.624540796067	-2.5637380499104	0.175164631848842	-14.6361626936354	1.6512848098521e-48	2.93221002663737e-46	3267	heavy metal efflux pump%2C CzcA family	Cadmium/cobalt/zinc resistance	K07239	NA	              Metabolism of cofactors and vitamins	               00780 Biotin metabolism	COG3696	P
LFTS_00206	332.975358455187	-2.91670752129926	0.200395776539739	-14.5547354922466	5.44963154056068e-48	9.03185600655591e-46	1389	type III secretion system ATPase%2C FliI/YscN	Motility	K02412	 Cell motility	              Cell motility	               02040 Flagellar assembly	COG1157	NU
LFTS_02335	839.175990444441	-2.39591397940004	0.165989807501499	-14.4341030058632	3.15726473019817e-47	4.90560007454541e-45	1494	flagellar hook-associated protein 2	Motility	K02407	 Cell motility	              Cell motility	               02040 Flagellar assembly	COG1345	N
LFTS_02039	276.806211135614	-3.13104648068536	0.217331528620252	-14.4067752183178	4.69107622373074e-47	6.86000911305565e-45	1236	outer membrane protein%2C cobalt-zinc-cadmium efflux system	Cadmium/cobalt/zinc resistance	K15725	NA	              Membrane transport	               03070 Bacterial secretion system	COG1538	M
LFTS_00212	312.42927592871	-3.29855323629669	0.230736056722436	-14.2957857699054	2.32467002547504e-46	3.21062760185053e-44	507	flagellar FliL protein	Motility	K02415	NA	              Cell motility	               02040 Flagellar assembly	COG1580	N
LFTS_02331	535.348624984069	-2.6766388301445	0.188059608020042	-14.2329278377483	5.7234423829535e-46	7.48867250738021e-44	2343	Glycosyltransferase involved in cell wall bisynthesis	Lipopolysaccharide synthesis	K00598	NA	              Membrane transport	               03070 Bacterial secretion system	COG0500	QR
LFTS_00957	129.670750974848	3.6188459185321	0.254819461399129	14.2016072817289	8.95350326671812e-46	1.11292045605306e-43	255	recombinase	NA	K04085	 Folding, sorting and degradation	              Folding, sorting and degradation	               04122 Sulfur relay system	COG0425	O
LFTS_00918	374.980701410879	-3.02675217473196	0.216320937643966	-13.9919519936326	1.74554331968576e-44	2.06639080606609e-42	399	Cu and Ag efflux protein CusF	Copper/silver resistance	K07810	 Signal transduction	              Signal transduction	               02020 Two-component system	COG5569	P
LFTS_02330	290.77749434726	-2.9380744563248	0.210477446732287	-13.9590939644086	2.76931955033686e-44	3.12933109188065e-42	1560	ADP-heptose:LPS heptosyltransferase	Lipopolysaccharide synthesis	K02843	 Glycan biosynthesis and metabolism	              Glycan biosynthesis and metabolism	               00540 Lipopolysaccharide biosynthesis	COG0859	M
LFTS_00211	532.242086555904	-2.39964637535378	0.17226889052602	-13.9296559467383	4.18365942823018e-44	4.5219901472088e-42	1374	flagellar hook protein FlgE	Motility	K02390	 Cell motility	              Cell motility	               02040 Flagellar assembly	COG1749	N
LFTS_00198	273.264326786077	-2.90292895307985	0.210204453101729	-13.8100259544691	2.217516796806e-43	2.29697781535822e-41	1221	two-component system%2C sensor histidine kinase FlrB	Motility	K10942	 Cellular community - prokaryotes; Signal transduction	              Signal transduction	               02020 Two-component system	COG0642	T
LFTS_01477	244.484236098022	2.93382031299934	0.216565201234549	13.5470532489746	8.24750741741089e-42	8.20132137587339e-40	1644	sulfite reductase (ferredoxin)	NA	K00366	 Energy metabolism	              Energy metabolism	               00910 Nitrogen metabolism	COG0155	P
LFTS_00219	259.081509238372	-3.19342683365303	0.236640248183907	-13.4948592141909	1.67675152779167e-41	1.60323242234234e-39	2109	flagellar biosynthesis protein FlhA	Motility	K02400	 Cell motility	              Cell motility	               02040 Flagellar assembly	COG1298	N
LFTS_00916	231.483477936787	-3.10890652983269	0.23216168126035	-13.3911268774209	6.81390077698163e-41	6.27383604873197e-39	372	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_02038	246.470375547814	-3.11638810835719	0.233607098873525	-13.3402971201847	1.34920715818172e-40	1.19790321258562e-38	984	RND family efflux transporter%2C MFP subunit	Cadmium/cobalt/zinc resistance	K15727	NA	              Membrane transport	               03070 Bacterial secretion system	COG0845	MV
LFTS_00732	207.994552289815	-3.07924920173782	0.239403382328292	-12.8621791880754	7.34756065680906e-38	6.29863303200942e-36	678	Cytochrome c553	Cytochrome c	K00406	 Energy metabolism; Signal transduction	              Energy metabolism	               00190 Oxidative phosphorylation	COG2010	C
LFTS_02340	843.631993706904	-2.13550137284028	0.166350752915962	-12.8373411926732	1.01293877738719e-37	8.3938860019485e-36	1686	flagellar hook-associated protein 1 FlgK	Motility	K02396	 Cell motility	              Cell motility	               02040 Flagellar assembly	COG1256	N
LFTS_00199	350.336217375217	-2.50680583093345	0.196534628628025	-12.755033799555	2.92247995253418e-37	2.3436403748387e-35	1470	two-component system%2C response regulator FlrC	Motility	K10943	 Cellular community - prokaryotes; Signal transduction	              Signal transduction	               02020 Two-component system	COG2204	T
LFTS_00203	489.963521549331	-2.4578621900458	0.194999878030807	-12.6044293712712	1.99612047027267e-36	1.55073609034308e-34	1596	flagellar M-ring protein FliF	Motility	K02409	 Cell motility	              Cell motility	               02040 Flagellar assembly	COG1766	NU
LFTS_02329	281.542966071212	-2.53089724156787	0.202640332544161	-12.4896026856664	8.50774420770122e-36	6.40916730313492e-34	1800	spore maturation protein CgeB	Lipopolysaccharide synthesis	K06320	NA	              Glycan biosynthesis and metabolism	               00540 Lipopolysaccharide biosynthesis	NA	
LFTS_02343	437.468726542612	-2.35700211030947	0.189188495687084	-12.4584853944181	1.25735924647429e-35	9.19351496098556e-34	861	flagellin	Motility	K02406	 Cell motility; Environmental adaptation; Signal transduction; Infectious diseases; Immune system	              Signal transduction	               02020 Two-component system	COG1344	N
LFTS_00197	519.664735252672	-2.86306846198095	0.23726737481379	-12.0668442689515	1.58080821657376e-33	1.12282549325782e-31	2160	Tetratricopeptide repeat-containing protein	Motility	K05807	NA	              Overview	               01200 Carbon metabolism	COG4105	M
LFTS_02334	235.6871846175	-2.57253135946049	0.214946969745476	-11.9682141251244	5.21387947949656e-33	3.60047344056346e-31	459	flagellar protein FliS	Motility	K02422	 Cell motility	              Cell motility	               02040 Flagellar assembly	COG1516	NU
LFTS_00209	287.919448921376	-2.45794918635333	0.207615764937968	-11.838933267364	2.45556271756583e-32	1.6498726799645e-30	1485	hook-length control protein FliK	Motility	K02414	 Cell motility	              Cell motility	               02040 Flagellar assembly	COG3144	N
LFTS_00429	587.278304655494	2.00243852398033	0.17247323523836	11.6101406761051	3.66012943433438e-31	2.39449520361981e-29	1182	sulfate adenylyltransferase	NA	K00958	 Energy metabolism; Nucleotide metabolism; Biosynthesis of other secondary metabolites; Metabolism of other amino acids	              Energy metabolism	               00920 Sulfur metabolism	COG2046	P
LFTS_02332	170.061301232086	-2.8660154761529	0.248131830631403	-11.5503741251574	7.34997850209256e-31	4.57827530640774e-29	981	Glycosyl transferases group 1	Lipopolysaccharide synthesis	K06320	NA	              Glycan biosynthesis and metabolism	               00540 Lipopolysaccharide biosynthesis	NA	
LFTS_02328	271.912890004606	-2.29853813649306	0.199004508132682	-11.5501812399172	7.36649285021358e-31	4.57827530640774e-29	1788	ADP-heptose:LPS heptosyltransferase	Lipopolysaccharide synthesis	K02843	 Glycan biosynthesis and metabolism	              Glycan biosynthesis and metabolism	               00540 Lipopolysaccharide biosynthesis	COG0859	M
LFTS_00214	149.054320366582	-3.13563450340023	0.272180074463395	-11.5204410520577	1.04076890271196e-30	6.31061339546814e-29	522	flagellar protein FliO/FliZ	Motility	K02418	 Cell motility	              Cell motility	               02040 Flagellar assembly	COG3190	N
LFTS_00222	195.477026630531	-3.11878196052237	0.27280361173107	-11.4323338343367	2.88255555161968e-30	1.7061983574587e-28	756	RNA polymerase sigma factor for flagellar operon FliA	Motility	K02405	 Cell motility; Cellular community - prokaryotes; Signal transduction	              Signal transduction	               02020 Two-component system	COG1191	K
LFTS_00210	181.035436204853	-2.65130798146573	0.23325918692676	-11.3663603839029	6.14988367638567e-30	3.5554908882546e-28	831	flagellar basal-body rod modification protein FlgD	Motility	K02389	 Cell motility	              Cell motility	               02040 Flagellar assembly	COG1843	N
LFTS_00205	182.673876864039	-2.59344993606695	0.237461465050894	-10.9215612542065	9.09193224704135e-28	5.13694171957836e-26	660	putative flagellar assembly protein	Motility	K02411	 Cell motility	              Cell motility	               02040 Flagellar assembly	COG1317	NU
LFTS_00201	192.033530912713	-2.37140692498717	0.221652741947392	-10.6987484303263	1.03162161362211e-26	5.6991362921435e-25	438	flagellar basal-body rod protein FlgC	Motility	K02388	 Cell motility	              Cell motility	               02040 Flagellar assembly	COG1558	N
LFTS_00208	345.743925081297	-2.61829037106939	0.24862081525688	-10.5312596950666	6.19991727404152e-26	3.35065094418853e-24	510	hypothetical protein	NA	K06213	NA	              Cell motility	               02040 Flagellar assembly	COG2239	P
LFTS_02342	478.070365161751	-1.83290237322776	0.18107258898691	-10.122472890473	4.39176891125023e-24	2.32296542837619e-22	360	anti-sigma-28 factor%2C FlgM family	Motility	K02398	 Cell motility; Cellular community - prokaryotes; Signal transduction	              Signal transduction	               02020 Two-component system	COG2747	KN
LFTS_00200	237.400752883306	-2.11646025382061	0.209778440145559	-10.0890265575054	6.17791071254747e-24	3.19964292320688e-22	375	flagellar basal-body rod protein FlgB	Motility	K02387	 Cell motility	              Cell motility	               02040 Flagellar assembly	COG1815	N
LFTS_02345	295.197195558944	-2.03407092580329	0.201772315554375	-10.0810208784819	6.7026068297877e-24	3.40054705690862e-22	1065	flagellar P-ring protein precursor FlgI	Motility	K02394	 Cell motility	              Cell motility	               02040 Flagellar assembly	COG1706	N
LFTS_00218	107.827417425839	-3.07387693245911	0.306211589432001	-10.0384082070862	1.03328068100595e-23	5.13747154596157e-22	1089	flagellar biosynthetic protein FlhB	Motility	K02401	 Cell motility	              Cell motility	               02040 Flagellar assembly	COG1377	N
LFTS_02347	126.550312480806	-2.68752210553657	0.270102788720174	-9.94999762227869	2.52189238811671e-23	1.22929891703101e-21	639	flagella basal body P-ring formation protein FlgA	Motility	K02386	 Cell motility	              Cell motility	               02040 Flagellar assembly	COG1261	N
LFTS_02344	171.427454633236	-2.59252978951708	0.260849610947154	-9.93879109155472	2.82231347596937e-23	1.34928294254997e-21	366	flagellar protein FlgJ	Motility	K02395	NA	              Cell motility	               02040 Flagellar assembly	COG1705	MN
LFTS_00213	135.888192557357	-2.64995458526082	0.271980132771675	-9.74319174807313	1.97259336536856e-22	9.25257944586084e-21	378	flagellar motor switch protein FliN/FliY	Motility	K02417	 Cell motility	              Cell motility	               02030 Bacterial chemotaxis	COG1886	NU
LFTS_01055	1438.78990402782	-1.20603537382132	0.126083803743012	-9.56534731676958	1.11825368953955e-21	5.14810865221355e-20	1287	serine/threonine-protein kinase HipA	NA	K07154	NA	              Carbohydrate metabolism	               00520 Amino sugar and nucleotide sugar metabolism	COG3550	T
LFTS_02341	339.850068301716	-1.80212923389652	0.189054042579157	-9.53234963564432	1.53762934844523e-21	6.95008465497243e-20	495	FlgN protein	Motility	K02399	 Cell motility	              Cell motility	               02040 Flagellar assembly	COG3418	NU
LFTS_00182	94.985712151071	-2.75516384644831	0.290504940713875	-9.48405159539761	2.44597131909146e-21	1.08583655343953e-19	555	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00223	132.219736507964	-2.43389772271214	0.25942399903416	-9.381929704937	6.4776163115166e-21	2.82514985095268e-19	795	chemotaxis protein methyltransferase CheR	Chemotaxis	K00575	 Signal transduction; Cell motility	              Signal transduction	               02020 Two-component system	COG1352	NT
LFTS_02337	276.840416765173	-1.87200573079873	0.199762093913079	-9.37117595299777	7.17288447411412e-21	3.07444669011167e-19	432	flagellar assembly factor FliW	Motility	K13626	NA	              Cell motility	               02040 Flagellar assembly	COG1699	N
LFTS_00064	1683.53124836037	1.34982933960477	0.144214633039896	9.359863913611	7.98394579900946e-21	3.36408292480297e-19	528	ATP synthase F0 subcomplex B subunit	ATP synthase	K02109	 Energy metabolism	              Energy metabolism	               00190 Oxidative phosphorylation	COG0711	C
LFTS_00202	173.83807800559	-2.22190747829339	0.238850186162202	-9.30251516230556	1.37161925176998e-20	5.68307576650029e-19	330	flagellar hook-basal body complex protein FliE	Motility	K02408	 Cell motility	              Cell motility	               02040 Flagellar assembly	COG1677	N
LFTS_02327	205.615989083396	-2.60343374545517	0.280736955620647	-9.27356977174435	1.8001788563832e-20	7.33646661798138e-19	654	hypothetical protein	NA	K11938	NA	              Overview	               01200 Carbon metabolism	COG0561	HR
LFTS_00204	299.429917188407	-2.25005083822586	0.244206175215183	-9.21373440390369	3.14971872918511e-20	1.26293560657326e-18	1005	flagellar motor switch protein FliG	Motility	K02410	 Cell motility	              Cell motility	               02030 Bacterial chemotaxis	COG1536	N
LFTS_02346	141.708505825128	-2.19219509681876	0.239432684932385	-9.15578880735447	5.39621155529421e-20	2.12936221054943e-18	627	flagellar L-ring protein precursor FlgH	Motility	K02393	 Cell motility	              Cell motility	               02040 Flagellar assembly	COG2063	N
LFTS_00207	263.994740061023	-2.25380693451639	0.247560995920221	-9.1040469688638	8.70271202679097e-20	3.38045970290662e-18	444	flagellar export protein FliJ	Motility	K02413	 Cell motility	              Cell motility	               02040 Flagellar assembly	COG2882	N
LFTS_00586	1494.51374543608	1.18057173794304	0.13078339953539	9.02692346381151	1.76565825715922e-19	6.75296373430434e-18	1191	succinyl-CoA synthetase beta subunit	Reductive TCA cycle carbon dioxide fixation	K01903	 Carbohydrate metabolism; Overview; Energy metabolism	              Overview	               01200 Carbon metabolism	COG0045	C
LFTS_02333	114.648611976239	-2.42447362825079	0.268891982505098	-9.01653372355506	1.94134672651041e-19	7.31240600318922e-18	345	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00731	298.803912510823	-1.97866046261914	0.222964016721987	-8.87434883758091	7.03437566728321e-19	2.61006834460688e-17	810	Cytochrome c	Cytochrome c	K03889	 Energy metabolism	              Energy metabolism	               00190 Oxidative phosphorylation	COG2010	C
LFTS_00513	601.760386780409	-1.35591763323161	0.155261840913826	-8.73310290056513	2.47779477944852e-18	9.05852620839563e-17	471	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_02310	255.45404421815	-1.90992969593802	0.221288049404629	-8.63096629518244	6.08358105466754e-18	2.19185253650775e-16	1272	Glycosyltransferase%2C catalytic subunit of cellulose synthase and poly-beta-1%2C6-N-acetylglucosamine synthase	Cellulose production	K00694	 Carbohydrate metabolism; Cellular community - prokaryotes	              Carbohydrate metabolism	               00500 Starch and sucrose metabolism	COG1215	N
LFTS_00662	659.022091960335	-1.85100905692093	0.214845489440672	-8.61553603820049	6.96151201759876e-18	2.47233126796436e-16	681	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00563	452.821870670106	1.80034290762305	0.209266455276487	8.60311274085665	7.75826986268967e-18	2.71648716600655e-16	324	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_02349	150.917953468773	-2.58110981880141	0.301603016518866	-8.55797083395536	1.14871414280784e-17	3.96625466530597e-16	804	flagellar basal-body rod protein FlgG	Motility	K02392	 Cell motility	              Cell motility	               02040 Flagellar assembly	COG1749	N
LFTS_00479	175.800634823285	-1.80572837328737	0.215992325741794	-8.36015060760082	6.26382400508223e-17	2.13313239405951e-15	2109	diguanylate cyclase (GGDEF) domain-containing protein	Genes encoding proteins with EAL and GGDEF domains	K14051	 Cellular community - prokaryotes	              Cellular community - prokaryotes	               02024 Quorum sensing	COG2199;COG2200;COG2202	T
LFTS_01887	833.501516623115	-1.39805446719707	0.167866391747501	-8.32837623209283	8.1958693775768e-17	2.75336909089945e-15	210	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00215	94.3495498297064	-2.52177665587604	0.305614160136868	-8.25150462513477	1.56412582067364e-16	5.18455572025955e-15	798	flagellar biosynthetic protein FliP	Motility	K02419	 Cell motility	              Cell motility	               02040 Flagellar assembly	COG1338	N
LFTS_02348	178.023559816059	-2.07855527801109	0.252016323183254	-8.24770098919216	1.61470776877569e-16	5.28179409628469e-15	786	flagellar basal-body rod protein FlgG	Motility	K02392	 Cell motility	              Cell motility	               02040 Flagellar assembly	COG1749	N
LFTS_00772	585.875654468223	-1.6539057306725	0.201738321059049	-8.19827250464923	2.43866042419212e-16	7.87338936953455e-15	687	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_02338	156.013184952523	-2.03160030919884	0.248581129028108	-8.17278575063967	3.01348859586077e-16	9.60452903757675e-15	243	carbon storage regulator%2C CsrA	Motility	K03563	 Cellular community - prokaryotes; Signal transduction	              Signal transduction	               02020 Two-component system	COG1551	T
LFTS_00065	1431.51952558089	1.16190301538429	0.142510851482536	8.15308450757994	3.54757525916219e-16	1.11636355623762e-14	570	F-type H+-transporting ATPase subunit delta	ATP synthase	K02113	 Energy metabolism	              Energy metabolism	               00190 Oxidative phosphorylation	COG0712	C
LFTS_00099	1057.67046016845	1.26544581846897	0.157587780734302	8.03010114472363	9.73923397279304e-16	3.02646695704544e-14	948	lipoprotein	NA	NA	NA	NA	NA	NA	NA
LFTS_00226	211.057313611765	-1.62323335902243	0.204773058010607	-7.92698695225005	2.2452686903283e-15	6.89103452364957e-14	1035	two-component system%2C chemotaxis family%2C response regulator CheB	Chemotaxis	K03412	 Signal transduction; Cell motility	              Signal transduction	               02020 Two-component system	COG2201	NT
LFTS_00771	382.400055467114	-2.23726858534992	0.28467611338193	-7.85899652335187	3.87222982915027e-15	1.17394675064239e-13	273	hypothetical protein	NA	K11261	 Energy metabolism; Overview	              Overview	               01200 Carbon metabolism	COG2191	C
LFTS_02251	3602.93470501743	1.12800062326633	0.144743118234281	7.79312092365286	6.53740018962338e-15	1.95806950257876e-13	618	Transglycosylase SLT domain-containing protein	NA	K08309	NA	              Replication and repair	               03030 DNA replication	COG0741	M
LFTS_02494	3322.12459336525	0.938480740504829	0.120855542828567	7.76530987772784	8.1445851057072e-15	2.41040935390335e-13	1131	ribonuclease-3	NA	K03685	 Translation; Cancers	              Translation	               03008 Ribosome biogenesis in eukaryotes	COG0571	K
LFTS_02472	686.600709305094	-1.15293140093969	0.148956270440541	-7.74006624581744	9.93650277144914e-15	2.90613481056736e-13	1032	hypothetical protein	NA	K05142	 Signaling molecules and interaction	              Signaling molecules and interaction	               04060 Cytokine-cytokine receptor interaction	NA	
LFTS_01548	213.371563911531	-1.55961666309007	0.202184115389678	-7.7138436918457	1.22083981468241e-14	3.52907881314008e-13	1119	methyl-accepting chemotaxis protein	Chemotaxis	K03406	 Signal transduction; Cell motility	              Signal transduction	               02020 Two-component system	COG0840	NT
LFTS_01663	2458.00013288416	0.951986546805868	0.125207831142182	7.60325083600259	2.88782974720833e-14	8.25189051903437e-13	375	small subunit ribosomal protein S12	NA	K02950	 Translation	              Translation	               03010 Ribosome	COG0048	J
LFTS_00225	722.259286660444	-1.32719506729956	0.175772730890129	-7.55063120757429	4.33153774542823e-14	1.22365941308348e-12	1941	two-component system%2C chemotaxis family%2C sensor kinase CheA	Chemotaxis	K03407	 Signal transduction; Cell motility	              Signal transduction	               02020 Two-component system	COG0643	NT
LFTS_00217	73.106954336866	-2.36858156609259	0.317101291332467	-7.46947940873956	8.05127060175855e-14	2.2489279456148e-12	789	flagellar biosynthetic protein FliR	Motility	K02421	 Cell motility	              Cell motility	               02040 Flagellar assembly	COG1684	N
LFTS_00920	439.974550328707	-2.96364448591165	0.398903449655512	-7.42947820699725	1.09026907978237e-13	3.01156548037663e-12	1260	membrane fusion protein%2C Cu(I)/Ag(I) efflux system	Copper/silver resistance	K07798	 Signal transduction	              Signal transduction	               02020 Two-component system	COG0845	MV
LFTS_01784	865.558067129531	1.79867765386458	0.242595351014795	7.41431213063468	1.22257678312923e-13	3.33991855259261e-12	1083	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00062	1673.41957942539	0.975789424890175	0.132011316556831	7.39171042559896	1.44951938809311e-13	3.89349937198312e-12	735	F-type H+-transporting ATPase subunit a	ATP synthase	K02108	 Energy metabolism	              Energy metabolism	               00190 Oxidative phosphorylation	COG0356	C
LFTS_01994	5767.07004387642	-1.22985962589969	0.166398088337392	-7.3910682399548	1.45653838131307e-13	3.89349937198312e-12	981	porphobilinogen synthase	NA	K01698	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00860 Porphyrin and chlorophyll metabolism	COG0113	H
LFTS_02276	40716.2706047874	1.12104299381188	0.15175074770376	7.38739683840192	1.49731217994316e-13	3.95991285036033e-12	555	Cytochrome C oxidase%2C cbb3-type%2C subunit III	Cytochrome cbb3 oxidase	K00406	 Energy metabolism; Signal transduction	              Energy metabolism	               00190 Oxidative phosphorylation	COG2010	C
LFTS_02213	214.10774526947	1.3548224910756	0.184543757612022	7.34147016732983	2.11260247922746e-13	5.52834711932575e-12	357	hypothetical protein	NA	K09132	NA	              Amino acid metabolism	               00270 Cysteine and methionine metabolism	COG1895	S
LFTS_00299	4548.64175731722	0.97075957207977	0.13288899624724	7.30504104548786	2.77182116120808e-13	7.1778618820451e-12	1059	hypothetical protein	NA	K07586	NA	              Translation	               00970 Aminoacyl-tRNA biosynthesis	COG3557	S
LFTS_00521	237.326829974904	-1.6723169368329	0.229278914806694	-7.2938104153312	3.01309353539613e-13	7.7222170402008e-12	3237	Tfp pilus assembly protein PilF	NA	K02656	NA	              Overview	               01200 Carbon metabolism	COG3063	NW
LFTS_01001	559.971228178528	1.07336275188826	0.14824147428399	7.24063732550306	4.46581144502516e-13	1.13285788289108e-11	1095	Streptogramin lyase	NA	K00504	NA	              Energy metabolism	               00190 Oxidative phosphorylation	NA	
LFTS_02311	588.157967027381	-1.088322019446	0.152725103250369	-7.12601920891723	1.03313305564862e-12	2.59431189529543e-11	2895	Tetratricopeptide repeat-containing protein	Cellulose production	K02656	NA	              Signal transduction	               02020 Two-component system	COG3063	NW
LFTS_01856	1076.22070209886	-1.11222432814216	0.156318171484733	-7.1151313860576	1.1180627646251e-12	2.77700862617836e-11	222	sec-independent protein translocase protein TatA	NA	K03116	 Folding, sorting and degradation; Membrane transport	              Folding, sorting and degradation	               03060 Protein export	COG1826	U
LFTS_02541	11156.9387220509	-0.908205322211017	0.12766661273303	-7.11388281374876	1.12822957057125e-12	2.77700862617836e-11	2316	acetolactate synthase%2C large subunit	NA	K01652	 Metabolism of cofactors and vitamins; Amino acid metabolism; Overview; Carbohydrate metabolism	              Overview	               01210 2-Oxocarboxylic acid metabolism	COG0028	EH
LFTS_00578	3147.95666431712	1.07544078823927	0.15207999503188	7.07154670812445	1.53216213150406e-12	3.73426966560694e-11	1251	citryl-CoA synthetase large subunit	Reductive TCA cycle carbon dioxide fixation	K15232	 Overview; Energy metabolism	              Overview	               01200 Carbon metabolism	NA	
LFTS_00370	371.555855898584	-1.15712247202527	0.165130520077946	-7.00732046068209	2.42925437837049e-12	5.86322949963985e-11	204	sulfur carrier protein	NA	K03154	 Folding, sorting and degradation	              Folding, sorting and degradation	               04122 Sulfur relay system	COG2104	H
LFTS_00740	649.130388186598	-1.18059751163654	0.168678269376925	-6.99910851585981	2.57596292656414e-12	6.15754214946005e-11	672	Cytochrome c553	Cytochrome c	K00406	 Energy metabolism; Signal transduction	              Energy metabolism	               00190 Oxidative phosphorylation	COG2010	C
LFTS_02339	719.811815750137	-1.16483427899934	0.167850335016628	-6.93971971449413	3.92878642328032e-12	9.3018695697856e-11	939	flagellar hook-associated protein 3 FlgL	Motility	K02397	 Cell motility	              Cell motility	               02040 Flagellar assembly	COG1344	N
LFTS_00229	255.214851143399	-1.4129855915976	0.203832007264598	-6.93210850719523	4.14613730079222e-12	9.72386540544289e-11	783	chemotaxis protein MotA	Chemotaxis	K02556	 Cell motility; Signal transduction	              Signal transduction	               02020 Two-component system	COG1291	N
LFTS_00463	1231.2892559806	-1.05592672912186	0.158614406075817	-6.65719309642741	2.7910640059372e-11	6.48465898949521e-10	576	peroxiredoxin Q/BCP	Oxidative stress response	K03564	NA	              Metabolism of cofactors and vitamins	               00730 Thiamine metabolism	COG1225	O
LFTS_00275	716.01501060224	1.35439832296538	0.204272181912669	6.63036107160404	3.34866718709439e-11	7.70813576584875e-10	768	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00133	222.862384522563	-1.37181838241196	0.207798919610116	-6.6016627275341	4.06571652107379e-11	9.27281768017379e-10	1077	regulatory protein%2C luxR family	Quorum sensing	K07684	 Signal transduction	              Signal transduction	               02020 Two-component system	COG2197	TK
LFTS_00762	573.998215757867	-1.0568340150222	0.160488298690062	-6.58511569783151	4.54531302055026e-11	1.02724074264436e-09	630	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00736	441.004951639465	-1.04937483471675	0.159393500030582	-6.58354847917518	4.59350713808361e-11	1.02878006714197e-09	1056	Cellulose biosynthesis protein BcsQ	Cellulose production	K03496	NA	              Energy metabolism	               00190 Oxidative phosphorylation	COG1192	N
LFTS_00830	427.056405218077	-1.12147236100999	0.170907523576102	-6.5618665436377	5.31383650541023e-11	1.17948192432588e-09	1260	tRNA nucleotidyltransferase (CCA-adding enzyme)	NA	K00974	 Translation	              Translation	               03013 RNA transport	COG0617	J
LFTS_01395	102.706068589867	-1.67001116282924	0.255164179267368	-6.54484954598333	5.95553117808699e-11	1.31021685917914e-09	1089	Transposase (or an inactivated derivative)	NA	K07493	NA	              Carbohydrate metabolism	               00010 Glycolysis / Gluconeogenesis	COG3328	X
LFTS_00939	1149.6668791101	-1.33899409402152	0.20666165155722	-6.47916090833518	9.22341012827257e-11	2.01135066481453e-09	696	transcriptional regulator%2C TetR family	NA	K09017	NA	              Folding, sorting and degradation	               04122 Sulfur relay system	COG1309	K
LFTS_02175	650.848757232411	-0.987107079964716	0.153608322505296	-6.42613019832102	1.30893303443681e-10	2.8295717596608e-09	759	sec-independent protein translocase protein TatC	NA	K03118	 Folding, sorting and degradation; Membrane transport	              Folding, sorting and degradation	               03060 Protein export	COG0805	U
LFTS_01974	10969.275694033	0.758731121336753	0.118275682805739	6.41493757075089	1.40880581200126e-10	3.01921659365097e-09	234	hypothetical protein	NA	K03975	NA	              Energy metabolism	               00190 Oxidative phosphorylation	COG0586	S
LFTS_01770	1160.3384668112	0.901153847746729	0.143507162577441	6.27950432272284	3.39654153087977e-10	7.21692499638214e-09	765	HDIG domain-containing protein	NA	K07814	NA	              Glycan biosynthesis and metabolism	               00540 Lipopolysaccharide biosynthesis	COG3437	T
LFTS_01733	464.842945017512	-1.53662094083629	0.245103328240568	-6.26927815247006	3.62725676444689e-10	7.64183077662285e-09	135	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01263	1496.79141591323	-0.961037093574704	0.153897326292757	-6.24466400245665	4.24712092794269e-10	8.87255682929877e-09	1251	IPT/TIG domain-containing protein	NA	K09103	NA	              Overview	               01200 Carbon metabolism	NA	
LFTS_02540	5129.8178728433	-1.10134844769794	0.177419362198459	-6.20760008406516	5.37998461386533e-10	1.11455347917243e-08	1020	ketol-acid reductoisomerase	NA	K00053	 Metabolism of cofactors and vitamins; Amino acid metabolism; Overview	              Overview	               01210 2-Oxocarboxylic acid metabolism	COG0059	EH
LFTS_01775	750.108312089225	1.08526265687303	0.175338653754553	6.18952315210669	6.03464894011092e-10	1.23984605496824e-08	264	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00433	1201.1565423596	-0.807385932595079	0.130754486789693	-6.17482391937869	6.62372488452364e-10	1.349719677289e-08	1521	MFS transporter%2C DHA2 family%2C multidrug resistance protein	NA	K03446	NA	              Metabolism of cofactors and vitamins	               00860 Porphyrin and chlorophyll metabolism	COG0477	GEPR
LFTS_00519	551.235295909653	-2.34914669582099	0.382543249653296	-6.14086563532372	8.20729862400748e-10	1.65880848612054e-08	888	PEP-CTERM protein-sorting domain-containing protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00569	54.528006720434	-2.13292679646933	0.348919994663977	-6.11293943909239	9.7812497864938e-10	1.96098282009868e-08	1848	glucosamine--fructose-6-phosphate aminotransferase (isomerizing)	Extracellular polysaccharide production and export	K00820	 Amino acid metabolism; Carbohydrate metabolism; Endocrine and metabolic diseases	              Carbohydrate metabolism	               00520 Amino sugar and nucleotide sugar metabolism	COG0449	M
LFTS_01385	230.991224794855	-1.18993753791233	0.195456794865804	-6.08798245530075	1.14342397958689e-09	2.2740416106024e-08	1779	ABC-2 type transport system ATP-binding protein	NA	K01990	NA	              Energy metabolism	               00920 Sulfur metabolism	COG1131;COG1134	VGM
LFTS_01673	3077.31692924848	1.07177983333253	0.176220764322305	6.08202919476765	1.18670952689106e-09	2.34139673321523e-08	1200	translation elongation factor 1A (EF-1A/EF-Tu)	NA	K02358	NA	              Folding, sorting and degradation	               03060 Protein export	COG0050	J
LFTS_00534	72.2148725740402	-1.97548007448608	0.327183984752092	-6.03782631959478	1.56204056302883e-09	3.05766365329895e-08	1416	two-component system%2C NtrC family%2C response regulator	Nitrate/nitrite regulation	K02481	NA	              Cell motility	               02040 Flagellar assembly	COG2204	T
LFTS_01554	1590.68824101923	0.716309992532318	0.11947052758377	5.99570460614277	2.02605017700959e-09	3.93496932816082e-08	300	acylphosphatase	NA	K01512	 Carbohydrate metabolism; Xenobiotics biodegradation and metabolism	              Carbohydrate metabolism	               00620 Pyruvate metabolism	COG1254	C
LFTS_00555	70.6740905360452	-2.05729433402071	0.344892464159164	-5.96503127151915	2.44587194609188e-09	4.71351756432901e-08	132	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00068	2611.73634064028	0.779093916224896	0.130826027021685	5.95519052256902	2.59769028216606e-09	4.9675831088191e-08	1392	F-type H+-transporting ATPase subunit beta	ATP synthase	K02133	 Neurodegenerative diseases; Energy metabolism	              Energy metabolism	               00190 Oxidative phosphorylation	COG0055	C
LFTS_01846	9195.55014725664	-1.28194968941047	0.217906260548353	-5.88303285176154	4.02815931938798e-09	7.64427791450269e-08	657	PAS fold-containing protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00092	643.842303368128	0.858895829988575	0.146970386163132	5.8440060777634	5.09601673878472e-09	9.59749819137788e-08	198	large subunit ribosomal protein L35	NA	K02916	 Translation	              Translation	               03010 Ribosome	COG0291	J
LFTS_00180	1496.4358214669	-1.00078241636267	0.172185589266193	-5.81223098069777	6.16457007843132e-09	1.15226475300603e-07	1404	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00327	614.504003284371	-0.90060328092584	0.155212582278739	-5.80238578408863	6.53779267039127e-09	1.2129069088502e-07	3264	Multidrug efflux pump subunit AcrB	NA	K03296	NA	              Signal transduction	               02020 Two-component system	COG0841	V
LFTS_01939	7060.05180612965	0.906359619543448	0.156526883726417	5.79044058097786	7.02020305722016e-09	1.29275739261106e-07	966	cytochrome c class I	NA	K02305	 Energy metabolism	              Energy metabolism	               00910 Nitrogen metabolism	NA	
LFTS_01444	369.088503971182	1.02703038383546	0.17781263001652	5.77591357678048	7.65366534658895e-09	1.3990450037956e-07	867	Cytochrome C biogenesis protein transmembrane region	NA	K08970	NA	              Overview	               01200 Carbon metabolism	COG2215	P
LFTS_00030	723.737022290295	-0.820201084031243	0.142896514680324	-5.73982567640736	9.4774057469764e-09	1.71976866328345e-07	582	carbonic anhydrase	Proton consuming reactions	K01673	 Energy metabolism	              Energy metabolism	               00910 Nitrogen metabolism	COG0288	P
LFTS_02302	461.26176576684	-0.947422202076093	0.165323781148525	-5.7307073156338	1.00012708053786e-08	1.80167820450517e-07	1470	outer membrane protein assembly factor BamB	NA	K05889	NA	              Lipid metabolism	               00564 Glycerophospholipid metabolism	NA	
LFTS_00940	890.675826539493	-1.26642200536925	0.222310032624933	-5.69664801185952	1.22185819566665e-08	2.18528019742971e-07	603	Cytochrome c554 and c-prime	Cytochrome c	K04013	NA	              Folding, sorting and degradation	               03018 RNA degradation	NA	
LFTS_01225	955.46659779957	-0.913559627461588	0.1620925906454	-5.63603569925123	1.74009322029153e-08	3.08990838974624e-07	564	Endonuclease%2C Uma2 family (restriction endonuclease fold)	NA	NA	NA	NA	NA	NA	NA
LFTS_00048	478.448563569894	-1.18465623676349	0.210414463785026	-5.63010838443982	1.80096412831751e-08	3.17531689574279e-07	1107	Chemoreceptor zinc-binding domain-containing protein	NA	K03406	 Signal transduction; Cell motility	              Signal transduction	               02020 Two-component system	COG0840	NT
LFTS_02252	1489.92094930535	1.07214572513495	0.191042123130947	5.61209071362793	1.99896593116113e-08	3.49959810201872e-07	333	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01382	102.717592227517	-1.82145913381591	0.326159078110693	-5.58457285434727	2.34275294559228e-08	4.07278589002966e-07	693	biopolymer transport protein ExbB	NA	K03561	NA	              Membrane transport	               03070 Bacterial secretion system	COG0811	U
LFTS_01292	1148.71908350534	0.760562516047015	0.137121644535975	5.54662627202865	2.91234322233098e-08	5.02783697966307e-07	1053	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase	Lipopolysaccharide synthesis	K02536	 Glycan biosynthesis and metabolism	              Glycan biosynthesis and metabolism	               00540 Lipopolysaccharide biosynthesis	COG1044	M
LFTS_00034	3007.23575277312	-0.716096864836177	0.129625873607773	-5.52433588222496	3.30734221472708e-08	5.67038120400794e-07	1044	EAL domain%2C c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	c-di-GMP specific phosphodiestereases (EAL domain-containing proteins)	K14051	 Cellular community - prokaryotes	              Cellular community - prokaryotes	               02024 Quorum sensing	COG2199;COG2200;COG2202	T
LFTS_00752	485.522713375626	-0.83336297056495	0.151093618295437	-5.5155404971205	3.47709662268536e-08	5.92059055068205e-07	312	Copper chaperone CopZ	Copper resistance	K08364	NA	              Energy metabolism	               00190 Oxidative phosphorylation	COG2608	P
LFTS_00066	2257.30667490818	0.750815562474206	0.136914273137487	5.48383704100924	4.16198185794941e-08	7.03856251623281e-07	1524	ATP synthase F1 subcomplex alpha subunit	ATP synthase	K02111	 Energy metabolism	              Energy metabolism	               00190 Oxidative phosphorylation	COG0056	C
LFTS_00570	58.2629436452779	-1.9370584955604	0.353982479474734	-5.4721874891513	4.44514181094034e-08	7.46663685270115e-07	1302	UDP-N-acetyl-D-glucosamine dehydrogenase	Extracellular polysaccharide production and export	K13015	 Carbohydrate metabolism	              Carbohydrate metabolism	               00520 Amino sugar and nucleotide sugar metabolism	COG0677	M
LFTS_00955	275.613216009719	0.986208958152679	0.181423212930856	5.43595795830463	5.45028059157567e-08	9.07109001388895e-07	783	cobalamin-5'-phosphate synthase	NA	K02233	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00860 Porphyrin and chlorophyll metabolism	COG0368	H
LFTS_01262	3888.84370970035	-0.849236756980442	0.156247380070953	-5.43520637974729	5.47330451360958e-08	9.07109001388895e-07	3411	hypothetical protein	NA	K06872	NA	              Overview	               01200 Carbon metabolism	COG1512	S
LFTS_00196	1187.94084089893	0.724196681411151	0.133737676110286	5.41505357707837	6.12703567482289e-08	1.00872918460991e-06	1035	sigma-54 specific transcriptional regulator%2C flagellar regulatory protein A	Motility	K10941	 Cellular community - prokaryotes; Signal transduction	              Signal transduction	               02020 Two-component system	COG2204	T
LFTS_01640	2615.34928891674	0.969723907580735	0.179307830353495	5.40815147709377	6.36785580120384e-08	1.04147957380215e-06	375	small subunit ribosomal protein S13	NA	K02952	 Translation	              Translation	               03010 Ribosome	COG0099	J
LFTS_00755	2024.85112407637	-1.09821716218625	0.203179204085067	-5.40516519459567	6.47486898110958e-08	1.05206041091754e-06	507	Heavy-metal resistance	Metal tolerance	K11165	NA	              Energy metabolism	               00190 Oxidative phosphorylation	NA	
LFTS_02083	286.94638280247	-0.984740257441185	0.182679210138785	-5.39054365679083	7.0244847593839e-08	1.12787936155602e-06	444	Rrf2 family protein	NA	K13771	 Infectious diseases	              Infectious diseases	               05132 Salmonella infection	COG1959	K
LFTS_00115	1606.93789829753	-0.699586317837591	0.129785059067939	-5.39034556721491	7.03223254389311e-08	1.12787936155602e-06	705	Modulator of FtsH protease YccA	NA	K06890	NA	              Overview	               01210 2-Oxocarboxylic acid metabolism	COG0670	R
LFTS_00183	365.79571630869	-0.996623839890899	0.185030874218959	-5.38625699142258	7.19400815707974e-08	1.14642976144232e-06	1365	methyl-accepting chemotaxis protein	Chemotaxis	K03406	 Signal transduction; Cell motility	              Signal transduction	               02020 Two-component system	COG0840	NT
LFTS_00644	3745.84928710263	0.798369763483251	0.148452689196759	5.37794072847743	7.53426096740062e-08	1.1930046347107e-06	1158	methionine adenosyltransferase	NA	K00789	 Amino acid metabolism; Overview	              Overview	               01230 Biosynthesis of amino acids	COG0192;COG1812	H
LFTS_01288	8951.35510883561	-0.735143360647905	0.137517750291279	-5.34580706193041	9.00150540875328e-08	1.41631281304814e-06	1056	Site-specific recombinase XerD	NA	K04763	NA	              Amino acid metabolism	               00270 Cysteine and methionine metabolism	COG0582	LX
LFTS_01611	2298.07410377315	-0.680361537585715	0.127918681109237	-5.31870350511756	1.04509281715879e-07	1.62921772560286e-06	1041	hypothetical protein	NA	K07718	 Signal transduction	              Signal transduction	               02020 Two-component system	COG2972	T
LFTS_00350	310.683158579294	1.40005038683044	0.263261447688788	5.31809879160696	1.04857134391173e-07	1.62921772560286e-06	564	L-2%2C4-diaminobutyric acid acetyltransferase	NA	K06718	 Amino acid metabolism	              Amino acid metabolism	               00260 Glycine, serine and threonine metabolism	COG0454	KR
LFTS_00266	979.345767355044	1.0917022393613	0.206824757345549	5.27839245829431	1.30322113540442e-07	2.01230294572384e-06	531	Tetratricopeptide repeat-containing protein	NA	K02656	NA	              Amino acid metabolism	               00250 Alanine, aspartate and glutamate metabolism	COG3063	NW
LFTS_01495	602.742014027475	-0.896599031982217	0.170433010184492	-5.26071229400724	1.43498417276222e-07	2.1865102994068e-06	1017	N-acetylneuraminic acid mutarotase	NA	K10450	NA	              Folding, sorting and degradation	               04120 Ubiquitin mediated proteolysis	NA	
LFTS_00227	555.925643471754	-1.10091716492555	0.209287896981259	-5.26030019320292	1.43820408540195e-07	2.1865102994068e-06	1674	methyl-accepting chemotaxis protein	Chemotaxis	K03406	 Signal transduction; Cell motility	              Signal transduction	               02020 Two-component system	COG0840	NT
LFTS_01847	669.584006481742	1.12522461422436	0.213949066251321	5.25931070389708	1.4459639306071e-07	2.1865102994068e-06	648	hypothetical protein	NA	K07244	NA	              Nucleotide metabolism	               00230 Purine metabolism	COG1824	P
LFTS_01897	1209.44278764638	-0.892875654456478	0.169792029239353	-5.25864293192354	1.45122365004876e-07	2.1865102994068e-06	402	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00348	665.067529661539	1.99627002214699	0.380733836074914	5.24321673830481	1.57800990487789e-07	2.3632124238111e-06	396	L-ectoine synthase	NA	K06720	 Amino acid metabolism	              Amino acid metabolism	               00260 Glycine, serine and threonine metabolism	NA	
LFTS_00580	11493.0679835196	0.786956362531381	0.150473712450952	5.22985942004916	1.69638988228274e-07	2.52528457925443e-06	153	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00426	2957.95788165748	-1.16812901804319	0.223473154353826	-5.22715590344998	1.72137347965231e-07	2.54722289905693e-06	123	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01677	2084.42810729588	0.736665118620438	0.14212727446463	5.1831368848473	2.18184784747298e-07	3.20951109397504e-06	762	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01451	11914.9431057352	0.774764975859481	0.15000610390586	5.1648896657279	2.40580792133332e-07	3.51814028966743e-06	3147	NADH-quinone oxidoreductase subunit F	NADH dehydrogenase	K05587	 Energy metabolism	              Energy metabolism	               00190 Oxidative phosphorylation	COG1894	C
LFTS_00359	589.352646335013	0.843788093765427	0.163561494887093	5.15884312715471	2.48480390318827e-07	3.61241082065851e-06	1455	hypothetical protein	NA	K09859	NA	              Membrane transport	               03070 Bacterial secretion system	COG3014	S
LFTS_01598	428.167885530757	-1.4123186297392	0.274176117034097	-5.15113659430651	2.58912522216765e-07	3.74218912924929e-06	165	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_02263	427.079864989255	0.841362115361988	0.163671073573589	5.14056697369739	2.73910665638329e-07	3.93608043223633e-06	702	phosphoribosyl-ATP pyrophosphatase /phosphoribosyl-AMP cyclohydrolase	NA	K11755	 Overview; Amino acid metabolism	              Overview	               01230 Biosynthesis of amino acids	COG0140;COG0139	E
LFTS_00063	642.958082786481	0.757693266162869	0.147729758047953	5.12891428358614	2.91417986244889e-07	4.16359260807353e-06	231	F-type H+-transporting ATPase subunit c	ATP synthase	K02128	 Neurodegenerative diseases; Energy metabolism	              Energy metabolism	               00190 Oxidative phosphorylation	COG0636	C
LFTS_02497	577.305483294962	0.814661455038335	0.159106063156169	5.12024142184142	3.05144758454018e-07	4.33479925438108e-06	399	Polymer-forming protein	NA	NA	NA	NA	NA	NA	NA
LFTS_02277	921.653226231964	-0.69347669848732	0.135673434904315	-5.11136685657291	3.19836200649833e-07	4.51768633417889e-06	1017	Acetoin utilization deacetylase AcuC	NA	K11407	 Cancers; Substance dependence	              Cancers	               05203 Viral carcinogenesis	NA	
LFTS_00657	634.744983438122	0.815924392550742	0.159847071795001	5.10440625147727	3.31834725839373e-07	4.66068434145017e-06	957	Endonuclease IV	NA	K01151	 Replication and repair	              Replication and repair	               03410 Base excision repair	COG0648	L
LFTS_01029	626.606479322444	-0.949732386797966	0.186322805237086	-5.09724177665466	3.44638047758088e-07	4.79075153049427e-06	240	hypothetical protein	NA	K08197	NA	              Signal transduction	               02020 Two-component system	NA	
LFTS_01935	968.352390183644	0.787095328170918	0.154421112548775	5.09707069959302	3.44949526934221e-07	4.79075153049427e-06	996	protease-4	NA	K04773	NA	              Energy metabolism	               00190 Oxidative phosphorylation	COG0616	O
LFTS_00550	38.7156771173579	-1.83067543115138	0.360082592856491	-5.08404312640846	3.69483986942683e-07	5.10298439744173e-06	858	polysaccharide export outer membrane protein	Extracellular polysaccharide production and export	K01991	 Cellular community - prokaryotes	              Cellular community - prokaryotes	               02026 Biofilm formation - Escherichia coli	COG1596	M
LFTS_02218	102.982578581099	-1.25440648668028	0.246829967925077	-5.08206721098406	3.73349251459729e-07	5.12787977419274e-06	942	Integrase core domain-containing protein	NA	K02315	NA	              Cell growth and death	               04112 Cell cycle - Caulobacter	COG1484	L
LFTS_02279	936.260684760372	-0.822803599773229	0.162239049699956	-5.0715509077187	3.94586677269604e-07	5.36222802775939e-06	360	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00943	1443.84458948662	-1.22446222418959	0.241440618870145	-5.07148395294722	3.94725554738523e-07	5.36222802775939e-06	1395	outer membrane protein	NA	K12340	 Drug resistance; Signal transduction; Membrane transport; Infectious diseases; Environmental adaptation	              Membrane transport	               03070 Bacterial secretion system	COG1538	M
LFTS_00537	64.4647922097893	-1.58268173905144	0.312261467589519	-5.06845033192485	4.0106760580712e-07	5.41877210889403e-06	924	UTP--glucose-1-phosphate uridylyltransferase	Extracellular polysaccharide production and export	K00973	 Biosynthesis of other secondary metabolites; Metabolism of terpenoids and polyketides	              Metabolism of terpenoids and polyketides	               00523 Polyketide sugar unit biosynthesis	COG1209	M
LFTS_00103	3084.73066144215	0.695539990145165	0.137283854904036	5.06643691373147	4.05330996623712e-07	5.44677220327864e-06	279	large subunit ribosomal protein L27	NA	K02899	 Translation	              Translation	               03010 Ribosome	COG0211	J
LFTS_00734	122.419109084713	-1.20753280948554	0.239012157881614	-5.0521815299607	4.367922647146e-07	5.83798693591664e-06	522	PEGA domain-containing protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00765	973.185254300337	-0.745377047765436	0.147820620896314	-5.04244295042074	4.59625810604911e-07	6.11031959980646e-06	747	Ferredoxin-NADP reductase	NA	K00523	 Carbohydrate metabolism	              Carbohydrate metabolism	               00520 Amino sugar and nucleotide sugar metabolism	COG0543	HC
LFTS_00340	5025.62179590924	-0.563091204708815	0.111983339592745	-5.02834802709612	4.94723370973643e-07	6.5419271289387e-06	1347	proteasome accessory factor A	NA	K13571	NA	              Amino acid metabolism	               00260 Glycine, serine and threonine metabolism	NA	
LFTS_02055	1413.5701239422	-0.751777663753485	0.149867096554375	-5.01629564485973	5.26772494572663e-07	6.92886995506688e-06	303	ParE toxin of type II toxin-antitoxin system%2C parDE	NA	NA	NA	NA	NA	NA	NA
LFTS_00518	61.5710042374113	-1.50424124037049	0.300274729587269	-5.00954989598388	5.4557481171447e-07	7.13841569432722e-06	696	PEP-CTERM protein-sorting domain-containing protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01941	5415.20948813127	0.809721322801169	0.161987970450058	4.99865095260769	5.77328011792478e-07	7.51433213254503e-06	831	hypothetical protein	NA	K03888	 Energy metabolism	              Energy metabolism	               00190 Oxidative phosphorylation	COG1290;COG2010	C
LFTS_02454	2449.39368921326	0.740728740243589	0.148600016594494	4.9847150573672	6.20531922828208e-07	8.03459562578607e-06	285	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01741	265.172998276242	-1.21834457478833	0.244664690679697	-4.97965019555406	6.36993016887611e-07	8.20499813462487e-06	612	hypothetical protein	NA	K15707	NA	              Folding, sorting and degradation	               04122 Sulfur relay system	NA	
LFTS_00331	953.683085694394	-0.722140208641766	0.145922889197499	-4.94877954112044	7.46802756725204e-07	9.56985388257143e-06	234	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01646	2253.95978563075	0.748318818075056	0.151375612778032	4.94345690393569	7.67493223653251e-07	9.78455463590759e-06	486	small subunit ribosomal protein S5	NA	K02988	 Translation	              Translation	               03010 Ribosome	COG0098	J
LFTS_02499	1020.84506740253	0.716304378982623	0.145111382161413	4.93623841433645	7.96437379111682e-07	1.01017516554676e-05	765	chromosome partitioning protein	NA	K03496	NA	              Folding, sorting and degradation	               04122 Sulfur relay system	COG1192	N
LFTS_02492	685.616276435893	0.927642544770205	0.188195842695312	4.92913409501851	8.25948712734737e-07	1.0422885786084e-05	234	TusA-related sulfurtransferase	NA	K04085	 Folding, sorting and degradation	              Folding, sorting and degradation	               04122 Sulfur relay system	COG0425	O
LFTS_01056	335.135546663757	-1.00454746898394	0.204663926232661	-4.90827810975334	9.18795030420843e-07	1.15359820486172e-05	270	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00181	560.523455848314	-1.20312282326752	0.24537193471828	-4.90326175505306	9.42582467561168e-07	1.1775175951543e-05	1020	ABC-type molybdate transport system%2C substrate-binding protein	NA	K02020	 Membrane transport	              Membrane transport	               02010 ABC transporters	COG0725	P
LFTS_01729	2072.1887822591	-0.958318087352127	0.196078808914058	-4.88741283496965	1.0216970559857e-06	1.26996944059022e-05	393	ribonuclease	NA	NA	NA	NA	NA	NA	NA
LFTS_02539	3695.31950328385	-0.992319195391598	0.203222626720104	-4.88291688483245	1.04527938428271e-06	1.29281818374469e-05	654	phosphatidylserine decarboxylase	NA	K01613	 Lipid metabolism	              Lipid metabolism	               00564 Glycerophospholipid metabolism	COG0688	I
LFTS_00651	1024.50488885335	0.901157619617361	0.184651669070274	4.88031125932797	1.05918538499022e-06	1.30353211241866e-05	243	NIL domain-containing protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01500	731.672484922134	0.683776437757431	0.140399300010918	4.87022682950883	1.11470210206275e-06	1.36509823927487e-05	915	phospholipid/cholesterol/gamma-HCH transport system substrate-binding protein	NA	K02067	 Membrane transport	              Membrane transport	               02010 ABC transporters	COG1463	M
LFTS_00437	7549.75504251901	-0.809778113892457	0.166487051573244	-4.86391047375961	1.15088985376928e-06	1.40250596885805e-05	717	PEGA domain-containing protein	NA	K07286	NA	              Overview	               01210 2-Oxocarboxylic acid metabolism	COG3056	S
LFTS_00697	313.2973599879	0.905063592500318	0.186386519451924	4.85584255321516	1.19875925318863e-06	1.45371487972045e-05	303	NADH-quinone oxidoreductase subunit K	NADH dehydrogenase	K00340	 Energy metabolism	              Energy metabolism	               00190 Oxidative phosphorylation	COG0713	C
LFTS_02503	783.142560746922	0.722723418454446	0.149257326799612	4.84213025886997	1.28454508108922e-06	1.55018401533389e-05	1536	protein translocase subunit yidC	NA	K03217	 Cellular community - prokaryotes; Folding, sorting and degradation; Membrane transport	              Folding, sorting and degradation	               03060 Protein export	COG0706	M
LFTS_01730	2045.13446562275	-0.877478346739456	0.181976137224308	-4.8219418222833	1.42167414329594e-06	1.70738257016122e-05	429	toxin-antitoxin system PIN domain toxin	NA	K07064	NA	              Cell growth and death	               04112 Cell cycle - Caulobacter	COG1848	R
LFTS_00579	14986.9158597943	0.736328878493669	0.15306952441194	4.81042115550097	1.50612606643604e-06	1.80011028901923e-05	987	succinyl-CoA synthetase alpha subunit	Reductive TCA cycle carbon dioxide fixation	K15233	 Overview; Energy metabolism	              Overview	               01200 Carbon metabolism	NA	
LFTS_00896	1693.30872062595	0.65354051740654	0.136688513945374	4.78123946586851	1.7421768382327e-06	2.06312242800297e-05	672	Cell division and transport-associated protein TolQ (TC 2.C.1.2.1)	NA	K03562	NA	              Membrane transport	               02010 ABC transporters	COG0811	U
LFTS_00125	1147.81506869422	0.805122144068388	0.168394390850126	4.78116961024529	1.74278242108055e-06	2.06312242800297e-05	699	peptidoglycan-associated lipoprotein	NA	K03640	NA	              Signal transduction	               04014 Ras signaling pathway	COG2885	M
LFTS_00347	510.797037182559	1.26847955761851	0.265682288883841	4.77442272477975	1.80223467178635e-06	2.12339118201937e-05	918	ectoine hydroxylase	NA	K10674	 Amino acid metabolism	              Amino acid metabolism	               00260 Glycine, serine and threonine metabolism	NA	
LFTS_00536	45.7927729388228	-1.70749198144498	0.358439299719744	-4.7636851840187	1.90088996943207e-06	2.2290624830227e-05	831	exosortase	Extracellular polysaccharide production and export	NA	NA	NA	NA	NA	NA
LFTS_02133	1722.23176206906	0.655970645063918	0.137916377065343	4.75629261021792	1.97180605795361e-06	2.30136613148952e-05	999	hypothetical protein	NA	K14829	NA	              Translation	               03010 Ribosome	COG2319	R
LFTS_01687	1976.64640035593	0.590011697613513	0.12417920650608	4.75129221883558	2.02120785163258e-06	2.34800127063485e-05	423	single-strand DNA-binding protein	NA	K03111	 Replication and repair	              Replication and repair	               03030 DNA replication	COG0629	L
LFTS_00689	3587.95620470187	0.564866226786197	0.118929250688468	4.74959880362694	2.03820597296275e-06	2.35673490641181e-05	555	NADH dehydrogenase subunit C	NADH dehydrogenase	K00332	 Energy metabolism	              Energy metabolism	               00190 Oxidative phosphorylation	COG0852	C
LFTS_00785	1077.21218720186	-0.616485856524347	0.129867078112474	-4.74705264401521	2.06402244205317e-06	2.37553694025193e-05	3081	ATP-dependent Clp protease ATP-binding subunit ClpC	Chaperones	K13525	 Folding, sorting and degradation; Infectious diseases	              Folding, sorting and degradation	               04141 Protein processing in endoplasmic reticulum	COG0464	MDT
LFTS_01275	416.623601331298	1.2571165996161	0.265051193603166	4.7429199715216	2.10659506002125e-06	2.41336189825475e-05	294	TM2 domain-containing membrane protein YozV	NA	K15771	 Membrane transport	              Membrane transport	               02010 ABC transporters	COG1175	G
LFTS_01971	19622.9051985691	0.512613156541595	0.108194334417309	4.73789278618259	2.15952005645132e-06	2.46264534877889e-05	333	hypothetical protein	NA	K00406	 Energy metabolism; Signal transduction	              Energy metabolism	               00190 Oxidative phosphorylation	COG2010	C
LFTS_00031	362.663031146466	-0.914682959285657	0.193448102009443	-4.72831188202098	2.26394245278911e-06	2.56993650120261e-05	1128	sulfide:quinone oxidoreductase	NA	K03885	 Energy metabolism	              Energy metabolism	               00190 Oxidative phosphorylation	COG1252	C
LFTS_00645	3287.34164932771	0.730832440002633	0.154878821468814	4.71873709440507	2.37313274601944e-06	2.68164000300196e-05	1257	adenosylhomocysteinase	NA	K01251	 Amino acid metabolism	              Amino acid metabolism	               00270 Cysteine and methionine metabolism	COG0499	H
LFTS_00535	51.1803264084761	-1.81260228129865	0.387698043340591	-4.67529385931485	2.93532996963051e-06	3.30191416493278e-05	714	EpsI family protein	Extracellular polysaccharide production and export	NA	NA	NA	NA	NA	NA
LFTS_00698	2830.15696781886	0.761137005703267	0.162992368132102	4.6697708268548	3.0153593244639e-06	3.37665913541318e-05	1920	NADH-quinone oxidoreductase subunit L	NADH dehydrogenase	K00341	 Energy metabolism	              Energy metabolism	               00190 Oxidative phosphorylation	COG1009	CP
LFTS_00571	40.3034308424254	-1.68106256050062	0.360499729787605	-4.66314513326001	3.11412965163479e-06	3.47162614975968e-05	513	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00325	232.392344948753	-0.931000924737815	0.200095748016856	-4.65277715276282	3.27494119736522e-06	3.6162779538523e-05	1419	Outer membrane protein TolC	NA	K12340	 Drug resistance; Signal transduction; Membrane transport; Infectious diseases; Environmental adaptation	              Membrane transport	               03070 Bacterial secretion system	COG1538	M
LFTS_00061	593.248335471479	0.75525896858833	0.162332534923218	4.65254219645841	3.27867617753083e-06	3.6162779538523e-05	270	Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter	ATP synthase	K02116	NA	              Energy metabolism	               00190 Oxidative phosphorylation	COG3312	C
LFTS_00795	680.757629162665	0.765842869032387	0.164627060355551	4.65198654084187	3.287525412593e-06	3.6162779538523e-05	318	hypothetical protein	NA	K00074	 Amino acid metabolism; Carbohydrate metabolism; Xenobiotics biodegradation and metabolism	              Carbohydrate metabolism	               00650 Butanoate metabolism	COG1250	I
LFTS_00942	1367.8230102331	-0.806227038643965	0.174202490319289	-4.62810283117229	3.69030777772381e-06	4.04145600679356e-05	1584	MFS transporter%2C DHA2 family%2C multidrug resistance protein	NA	K03446	NA	              Folding, sorting and degradation	               03018 RNA degradation	COG0477	GEPR
LFTS_00646	1062.4785392436	0.823894823839954	0.178164153409609	4.62435797590426	3.75760441188892e-06	4.09710726664731e-05	231	sulfur carrier protein	NA	K03154	 Folding, sorting and degradation	              Folding, sorting and degradation	               04122 Sulfur relay system	COG2104	H
LFTS_02054	676.906881919202	-0.763981090903431	0.165845968598951	-4.60657016481897	4.09364972338168e-06	4.44402323682396e-05	336	small multidrug resistance family-3 protein	NA	K09771	NA	              Membrane transport	               02010 ABC transporters	COG1742	R
LFTS_00546	57.0299030171272	-1.4283601199633	0.310678196805304	-4.59755507354907	4.27477652404299e-06	4.62047584294386e-05	1185	Glycosyltransferase involved in cell wall bisynthesis	Extracellular polysaccharide production and export	K13668	NA	              Glycan biosynthesis and metabolism	               00540 Lipopolysaccharide biosynthesis	COG0438	M
LFTS_00741	807.327184337948	-1.02216439839895	0.222668793767587	-4.590514822952	4.42154053646718e-06	4.75841981543611e-05	819	Cytochrome c	Cytochrome c	K03889	 Energy metabolism	              Energy metabolism	               00190 Oxidative phosphorylation	COG2010	C
LFTS_01293	919.117884168929	0.635982585503197	0.138864862270519	4.5798668943642	4.65271936661615e-06	4.96472760976869e-05	522	3-hydroxyacyl-[acyl-carrier-protein] dehydratase	Lipopolysaccharide synthesis	K02372	 Lipid metabolism; Overview; Metabolism of cofactors and vitamins	              Overview	               01212 Fatty acid metabolism	COG0764	I
LFTS_02008	1626.11124204208	-0.739252637930887	0.161414300019015	-4.57984601019736	4.65318396249439e-06	4.96472760976869e-05	1161	LPP20 lipoprotein	NA	K07009	NA	              Membrane transport	               02060 Phosphotransferase system (PTS)	COG3442	R
LFTS_00076	5414.18976789131	-0.966526589951015	0.211328903393408	-4.57356553898232	4.79493597290045e-06	5.09410719172244e-05	498	Heavy-metal resistance	Metal tolerance	K08317	NA	              Replication and repair	               03430 Mismatch repair	COG0371	C
LFTS_00742	148.868571387682	-1.14230422041693	0.250455323120743	-4.56091013033184	5.09323776412358e-06	5.38799535387711e-05	2211	DNA polymerase-2	NA	K02319	 Replication and repair; Nucleotide metabolism	              Nucleotide metabolism	               00230 Purine metabolism	COG0417	L
LFTS_02024	211.406573772029	-0.877826201788648	0.192701942390038	-4.55535730933051	5.2296606063223e-06	5.50887129971069e-05	981	ISXO2-like transposase domain-containing protein	NA	K07489	NA	              Folding, sorting and degradation	               04122 Sulfur relay system	COG3677	X
LFTS_00649	3279.97138774405	0.64981111039615	0.143658757158525	4.52329620030818	6.08839422190696e-06	6.38639157622814e-05	1281	threonine synthase	NA	K01733	 Metabolism of cofactors and vitamins; Overview; Amino acid metabolism	              Overview	               01230 Biosynthesis of amino acids	COG0498	E
LFTS_00324	81.0781499954869	-1.49101222912895	0.329937876978287	-4.51906959814459	6.21119761804406e-06	6.48783078926787e-05	339	ArsR family transcriptional regulator	Arsenic resistance	K03892	NA	              Signal transduction	               02020 Two-component system	COG0640	K
LFTS_01387	824.218309158882	-0.654813860207681	0.14591492065416	-4.48764154667695	7.2015963934479e-06	7.49086553728514e-05	1452	outer membrane protein	NA	K12340	 Drug resistance; Signal transduction; Membrane transport; Infectious diseases; Environmental adaptation	              Membrane transport	               03070 Bacterial secretion system	COG1538	M
LFTS_01503	1974.40710606341	0.537668997726667	0.119923672783096	4.48342671008032	7.3453838154989e-06	7.60859340222095e-05	702	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00141	1477.77613862538	0.630440044289509	0.141056592686226	4.46941211526279	7.84348781892132e-06	8.09083432275452e-05	393	Peroxiredoxin family protein	Oxidative stress response	K07092	NA	              Overview	               01230 Biosynthesis of amino acids	COG2044	R
LFTS_02325	2490.17517901811	-0.872542151510399	0.195285588823322	-4.4680314444493	7.89427038036228e-06	8.10956866346307e-05	420	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_02488	2220.23680822425	-0.633952312173689	0.14208645837032	-4.46173632198938	8.12982234509882e-06	8.31717627568546e-05	897	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase	Lipopolysaccharide synthesis	K02535	 Glycan biosynthesis and metabolism	              Glycan biosynthesis and metabolism	               00540 Lipopolysaccharide biosynthesis	COG0774	M
LFTS_00650	938.518477610763	0.620770228789511	0.139244741825826	4.45812330612816	8.26803387671375e-06	8.42390664652065e-05	282	molybdopterin synthase sulfur carrier subunit	NA	K03636	 Folding, sorting and degradation	              Folding, sorting and degradation	               04122 Sulfur relay system	COG1977	H
LFTS_00812	755.269930586192	-0.600980532861209	0.13507486340043	-4.4492403525858	8.61745376590659e-06	8.74407757634441e-05	768	pyridoxine 5-phosphate synthase	NA	K03474	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00750 Vitamin B6 metabolism	COG0854	H
LFTS_00549	32.0711094340307	-1.6437444623383	0.371887595672793	-4.42000346735028	9.86993176010756e-06	9.94128317131236e-05	1515	putative phosphohydrolase or phosphomutase%2C AlkP superfamily	NA	NA	NA	NA	NA	NA	NA
LFTS_00820	806.534201663659	0.658782080795524	0.149051041502144	4.41984218396789	9.87730065693545e-06	9.94128317131236e-05	798	Enoyl-[acyl-carrier-protein] reductase [NADH]	NA	K00208	 Lipid metabolism; Overview; Metabolism of cofactors and vitamins	              Overview	               01212 Fatty acid metabolism	COG0623	I
LFTS_00407	452.786734640633	-0.806342893313574	0.182653989277284	-4.41459229280494	1.01200534817787e-05	0.000101445374821379	672	putative phosphoribosyltransferase	NA	K07100	NA	              Cellular community - prokaryotes	               02024 Quorum sensing	COG1926	R
LFTS_01635	310.249914264795	0.752746005879507	0.170829601223552	4.40641434791178	1.05095838146852e-05	0.000104927009491195	867	dTDP-4-dehydrorhamnose reductase	Lipopolysaccharide synthesis	K00067	 Biosynthesis of other secondary metabolites; Metabolism of terpenoids and polyketides	              Metabolism of terpenoids and polyketides	               00523 Polyketide sugar unit biosynthesis	COG1091	M
LFTS_02040	167.958752322389	-1.04820019736788	0.237978292939332	-4.4046042368877	1.05977174141034e-05	0.000105383701965844	228	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01810	753.764676047211	1.05705829985131	0.240234797441802	4.40010486036013	1.08198580689307e-05	0.000107164012587098	1188	hypothetical protein	Lipopolysaccharide synthesis	NA	NA	NA	NA	NA	NA
LFTS_01367	1793.84258825405	-0.552502979781768	0.125612277456858	-4.39847912137033	1.0901211148721e-05	0.000107195337674701	1779	NAD+ synthase (glutamine-hydrolysing)	NA	K01950	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00760 Nicotinate and nicotinamide metabolism	COG0171;COG0388	HR
LFTS_00474	627.342286569728	-0.687736102095858	0.156363400874062	-4.3983189048809	1.09092600288412e-05	0.000107195337674701	1353	MoxR-like ATPase	NA	K04748	NA	              Translation	               00970 Aminoacyl-tRNA biosynthesis	COG0714	R
LFTS_00242	763.48683877247	-0.665696151433776	0.151400446962782	-4.39692329044062	1.09796126338142e-05	0.000107461877982921	528	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase	NA	K00950	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00790 Folate biosynthesis	COG0801	H
LFTS_00548	20.4153958854103	-1.76725916149599	0.402422666113805	-4.39154975678286	1.12545572412015e-05	0.000109720899222067	798	Polysaccharide deacetylase	Extracellular polysaccharide production and export	K11931	 Cellular community - prokaryotes	              Cellular community - prokaryotes	               02026 Biofilm formation - Escherichia coli	COG0726	GM
LFTS_00876	2998.48947737399	0.49510929461557	0.112779187713709	4.3900767921153	1.13310638711227e-05	0.00011003525306098	963	malate dehydrogenase (NAD)	Reductive TCA cycle carbon dioxide fixation	K00024	 Carbohydrate metabolism; Overview; Amino acid metabolism; Energy metabolism	              Overview	               01200 Carbon metabolism	COG0039	C
LFTS_00326	170.79199378045	-0.912123309562673	0.207850678148862	-4.38835859322726	1.14209354778019e-05	0.000110476442014846	1050	RND family efflux transporter%2C MFP subunit	Cadmium/cobalt/zinc resistance	K15727	NA	              Transport and catabolism	               04146 Peroxisome	COG0845	MV
LFTS_00966	4003.23788457865	0.563820837512912	0.128517038556125	4.38712908301793	1.14856631135311e-05	0.000110671932171466	351	putative isocitrate dehydrogenase (NADP)	Reductive TCA cycle carbon dioxide fixation; Oxidative stress response	NA	NA	NA	NA	NA	NA
LFTS_00480	1239.24398989523	0.657623993790539	0.150096531358987	4.3813403803296	1.17951438225786e-05	0.000113215164258418	621	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01496	184.970117728871	-1.12828267690804	0.25761687078604	-4.37969250020554	1.1884689495777e-05	0.000113635915717314	399	Sel1 repeat protein	NA	K07126	NA	              Overview	               01200 Carbon metabolism	COG0790	T
LFTS_01650	3588.72712299578	0.704893877645401	0.161000075435966	4.37822079111854	1.19652102174152e-05	0.000113967481227947	681	large subunit ribosomal protein L5	NA	K02931	 Translation	              Translation	               03010 Ribosome	COG0094	J
LFTS_00002	1447.61361002124	-0.598506928811919	0.136819716943924	-4.37442016531301	1.21755670739324e-05	0.000115528472312198	1164	DNA polymerase-3 subunit beta	NA	K02338	 Replication and repair; Nucleotide metabolism	              Nucleotide metabolism	               00230 Purine metabolism	COG0592	L
LFTS_02212	367.46981257488	0.940551830448217	0.215280116257242	4.36896749593138	1.24835343255736e-05	0.00011800025221816	441	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00759	830.528823685992	-0.711639537329259	0.162994592170418	-4.3660315833375	1.2652419310797e-05	0.000119143615176672	879	high-affinity iron transporter	NA	K07243	NA	              Membrane transport	               03070 Bacterial secretion system	COG0672	P
LFTS_00552	112.08200799796	-1.08638832130739	0.248952450721668	-4.3638386292569	1.27799864887438e-05	0.000119626760921329	1983	tyrosine-protein kinase Etk/Wzc	Extracellular polysaccharide production and export	K00903	NA	              Signal transduction	               02020 Two-component system	COG0489	D
LFTS_01462	995.270595030301	-0.613944767612295	0.140700168142119	-4.36349704281917	1.27999671782275e-05	0.000119626760921329	879	3-hydroxyisobutyrate dehydrogenase	NA	K00020	 Amino acid metabolism	              Amino acid metabolism	               00280 Valine, leucine and isoleucine degradation	COG2084	I
LFTS_00703	474.876763444098	0.753844336179079	0.173191667905612	4.35265937036831	1.34496034904157e-05	0.000125227394296529	1518	ammonium transporter%2C Amt family	Ammonia & glutamate conversion to glutamine	K03320	NA	              Signal transduction	               02020 Two-component system	COG0004	P
LFTS_00585	3730.53067762184	0.57871161097395	0.13324808888329	4.34311377989694	1.40477332147683e-05	0.000130062978941386	1623	succinate dehydrogenase / fumarate reductase flavoprotein subunit	Reductive TCA cycle carbon dioxide fixation; Succinate dehydrogenase / fumarate reductase	K00239	 Carbohydrate metabolism; Overview; Energy metabolism; Infectious diseases	              Overview	               01200 Carbon metabolism	COG1053	C
LFTS_01006	189.338187161354	0.801634974373964	0.184593257183522	4.34270994837575	1.40735886304235e-05	0.000130062978941386	1815	diguanylate cyclase (GGDEF) domain-containing protein	Genes encoding proteins with EAL and GGDEF domains	K14051	 Cellular community - prokaryotes	              Cellular community - prokaryotes	               02024 Quorum sensing	COG2199;COG2200;COG2202	T
LFTS_00230	213.733685416729	-1.01170552858098	0.233605007856069	-4.33083835773043	1.4854269892546e-05	0.000136769314640257	786	chemotaxis protein MotB	Chemotaxis	K02557	 Cell motility	              Cell motility	               02030 Bacterial chemotaxis	COG1360	N
LFTS_01565	334.320430508597	-0.839590867960492	0.193979994650037	-4.32823430826056	1.50309515400516e-05	0.000137885407854495	816	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_02278	1977.08914874105	-0.709186042147956	0.164086123320998	-4.32203545183763	1.54596340251123e-05	0.000141296508038342	453	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00475	510.395875528989	-0.651487184881095	0.150766996893981	-4.3211524955904	1.5521635173853e-05	0.000141343534953109	1656	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00482	794.986225805852	0.656191811626859	0.152016299636071	4.31658850529708	1.58459162412447e-05	0.000143769882393191	1071	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01513	624.32284971914	0.629433343141132	0.146381260908027	4.29995847307678	1.70830117240621e-05	0.000154430425985521	1425	oligopeptide transport system substrate-binding protein	NA	K15580	 Cellular community - prokaryotes; Drug resistance; Membrane transport	              Membrane transport	               02010 ABC transporters	COG4166	E
LFTS_00224	196.653993142708	-1.04822219016592	0.244091118932221	-4.29438889358766	1.75175180496074e-05	0.000157360828191212	381	two-component system%2C chemotaxis family%2C response regulator CheY	Chemotaxis	K03413	 Signal transduction; Cell motility	              Signal transduction	               02020 Two-component system	COG0784	T
LFTS_00330	3327.24137440356	0.694224132832339	0.161666167560635	4.29418315104156	1.75337688692541e-05	0.000157360828191212	348	hypothetical protein	NA	K07001	NA	              Metabolism of cofactors and vitamins	               00130 Ubiquinone and other terpenoid-quinone biosynthesis	COG1752	R
LFTS_00356	233.156526560299	0.789109997105949	0.184916929163056	4.26737563011403	1.97785971091596e-05	0.000176797589944009	1995	AcrB/AcrD/AcrF family protein	NA	K03296	NA	              Amino acid metabolism	               00260 Glycine, serine and threonine metabolism	COG0841	V
LFTS_00926	2533.18817235966	0.902517443061502	0.211527635537654	4.26666445151487	1.98417246960493e-05	0.000176797589944009	999	Peptidase family M23	NA	K08259	NA	              Translation	               00970 Aminoacyl-tRNA biosynthesis	NA	
LFTS_01557	573.162959832694	-1.19737668637375	0.280727586249237	-4.26526193015706	1.99667818955729e-05	0.000177276499258551	195	DNA binding domain-containing protein%2C excisionase family	NA	K07450	NA	              Overview	               01200 Carbon metabolism	COG2452	X
LFTS_02538	3051.87323572264	-0.592801824463936	0.139035546864687	-4.26367096639585	2.01095503253257e-05	0.000177908690778504	837	CDP-diacylglycerol---serine O-phosphatidyltransferase	NA	K00998	 Amino acid metabolism; Lipid metabolism	              Lipid metabolism	               00564 Glycerophospholipid metabolism	COG1502	I
LFTS_01942	4069.73245656146	0.808984561931236	0.190572282956721	4.24502739527425	2.18566716101456e-05	0.000192679736251141	762	hypothetical protein	NA	K02635	 Energy metabolism	              Energy metabolism	               00195 Photosynthesis	COG1290	C
LFTS_02195	339.690088311635	-0.73487360719005	0.173277134651773	-4.241030466408	2.22495929945693e-05	0.000195450488284449	447	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00087	926.495552665395	-0.799756012691657	0.188749942367561	-4.23711924178635	2.26405911099488e-05	0.000198184892603285	891	Peptidase family M23	NA	K08259	NA	              Overview	               01200 Carbon metabolism	NA	
LFTS_02010	999.931265120875	-0.663366413599838	0.156646446910111	-4.23480025678783	2.28754946806141e-05	0.000199538525529848	2049	putative membrane protein YccC	NA	K03468	NA	              Metabolism of cofactors and vitamins	               00790 Folate biosynthesis	COG1289	S
LFTS_01688	1487.13100397393	0.632310201939005	0.149687547352938	4.22420043030114	2.39790576881216e-05	0.000208433347596749	369	small subunit ribosomal protein S6	NA	K02990	 Translation	              Translation	               03010 Ribosome	COG0360	J
LFTS_01669	1985.75369543941	0.65870552051802	0.156270634028339	4.21515868681102	2.49602619759156e-05	0.000216206311052704	426	LSU ribosomal protein L11P	NA	K02867	 Translation	              Translation	               03010 Ribosome	COG0080	J
LFTS_00358	1200.01258976457	0.689456788230437	0.163722644968339	4.21112661821317	2.54100266910979e-05	0.000219337938729408	618	hypothetical protein	NA	K07337	NA	              Membrane transport	               03070 Bacterial secretion system	COG3417	M
LFTS_01085	435.109775971567	-0.736852349290703	0.17536658211066	-4.20178314717758	2.6482074999421e-05	0.000227800825081524	1590	putative transposase	NA	K07496	NA	              Metabolism of cofactors and vitamins	               00730 Thiamine metabolism	COG0675	X
LFTS_01553	2571.2100477302	0.493799561362739	0.117597696300007	4.19905811847702	2.68027526994509e-05	0.000229764286933914	1500	adenine phosphoribosyltransferase	NA	K03087	 Cellular community - prokaryotes	              Cellular community - prokaryotes	               05111 Biofilm formation - Vibrio cholerae	COG0568	K
LFTS_01944	18257.2422579209	0.696572353899893	0.166087262477203	4.19401430013637	2.74060693217617e-05	0.000234128825889689	1842	NADPH-dependent glutamate synthase beta chain	NA	K00266	 Energy metabolism; Amino acid metabolism; Overview	              Overview	               01230 Biosynthesis of amino acids	COG0493	ER
LFTS_00156	537.635303117029	0.714729473379162	0.170489405788584	4.19222220919382	2.76235226267878e-05	0.000235178346747241	1623	DNA polymerase-3 subunit gamma/tau	NA	K02343	 Replication and repair; Nucleotide metabolism	              Nucleotide metabolism	               00230 Purine metabolism	COG2812	L
LFTS_00560	279.229923510231	-0.864051293666216	0.20656725373535	-4.18290546077173	2.87807095350002e-05	0.00024419400649833	408	MerR family transcriptional regulator%2C mercuric resistance operon regulatory protein	Mercury resistance	K08365	NA	              Metabolism of cofactors and vitamins	               00860 Porphyrin and chlorophyll metabolism	COG0789	K
LFTS_00404	2381.8781240781	-0.59145997798508	0.141675966515056	-4.17473755453242	2.98329773862587e-05	0.000252261162524623	567	putative kinase inhibitor	NA	K06910	NA	              Cellular community - prokaryotes	               02024 Quorum sensing	COG1881	R
LFTS_00944	597.521871936798	-0.712073864605823	0.170914713661014	-4.16625256745375	3.09647634251137e-05	0.000260943735168924	993	membrane fusion protein%2C multidrug efflux system	NA	K03543	NA	              Folding, sorting and degradation	               03018 RNA degradation	COG1566	V
LFTS_00758	301.130004688012	-1.01799850852725	0.244534995696156	-4.16299722511763	3.1409718624347e-05	0.000263799190878806	321	Cupredoxin-like domain-containing protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00934	684.288847518054	-0.818589317974332	0.196854807048035	-4.15834050613043	3.20567937221569e-05	0.000268327236341017	114	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00104	2378.18049896085	0.607562507588322	0.146152972931676	4.15703146779196	3.22409595812919e-05	0.000268963172882858	1083	GTP-binding protein	NA	K03979	NA	              Translation	               03010 Ribosome	COG0536	DL
LFTS_00386	70.1866547663621	-1.24653095067724	0.301157492764634	-4.13913311348839	3.48620637400132e-05	0.000289856489824993	252	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_02016	250.055541180156	-0.750846883346639	0.181748612271518	-4.13123860458936	3.60813822826649e-05	0.000298994387849017	906	Pirin	NA	K06911	NA	              Metabolism of cofactors and vitamins	               00790 Folate biosynthesis	COG1741	R
LFTS_00238	93.8977755470021	1.3422450879089	0.325060657966163	4.12921420976333	3.64005151936135e-05	0.000300636813193765	450	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00504	105.052398294949	-1.0102664729726	0.244745234775429	-4.12782898061155	3.66204301227142e-05	0.00030145162014923	636	GGDEF domain-containing protein%2C diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	Putative diguanylate cyclases (GGDEF domain-containing proteins)	K13591	 Cell growth and death	              Cell growth and death	               04112 Cell cycle - Caulobacter	COG3706	TK
LFTS_01651	1131.81245556692	0.851547988312187	0.206614760577605	4.12142862364543	3.76530133440467e-05	0.000308928683740264	201	large subunit ribosomal protein L29	NA	K02904	 Translation	              Translation	               03010 Ribosome	COG0255	J
LFTS_02301	148.444821727985	-0.900396385666253	0.21882301888229	-4.11472426559748	3.8764251425087e-05	0.000316999766588047	744	Putative zinc- or iron-chelating domain-containing protein	NA	K06940	NA	              Lipid metabolism	               00564 Glycerophospholipid metabolism	COG0727	R
LFTS_00457	75.4606704122998	-1.17645178183643	0.285990505681686	-4.11360432764103	3.89528874559192e-05	0.000317497961362017	639	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01624	542.771900171801	0.74441726036423	0.181038745821197	4.11192232351993	3.92378324068296e-05	0.000318775331252871	774	hypothetical protein	NA	K09778	NA	              Nucleotide metabolism	               00230 Purine metabolism	COG2121	S
LFTS_00722	586.525120540175	-0.609186299932309	0.14831353445352	-4.10742217274327	4.00099528261714e-05	0.000323989389986521	1203	type II secretion system protein F (GspF)	NA	K02455	 Cellular community - prokaryotes; Membrane transport	              Membrane transport	               03070 Bacterial secretion system	COG1459	NUW
LFTS_02473	1254.30510110457	-0.639901116206483	0.155987794570072	-4.10225119196125	4.0914972919759e-05	0.000330242281423769	876	DNA-(apurinic or apyrimidinic site) lyase	NA	K10563	 Replication and repair	              Replication and repair	               03410 Base excision repair	COG0266	L
LFTS_00853	1588.45873331594	0.527531378674792	0.128738449113073	4.09769872411197	4.17277891132982e-05	0.000335712892348412	1695	DNA repair protein RecN (Recombination protein N)	NA	K03631	NA	              Immune system	               04621 NOD-like receptor signaling pathway	COG0497	L
LFTS_02271	699.528389437889	0.720758875206051	0.176525226507067	4.08303611595817	4.44511115386765e-05	0.000356469236403709	1329	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	NA	K00790	 Carbohydrate metabolism; Glycan biosynthesis and metabolism	              Carbohydrate metabolism	               00520 Amino sugar and nucleotide sugar metabolism	COG0766	M
LFTS_01566	1096.87335630025	-0.589085603460844	0.14435769726678	-4.08073566297048	4.4893386824232e-05	0.00035885839114161	1431	hypothetical protein	NA	K04034	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00860 Porphyrin and chlorophyll metabolism	COG1032	R
LFTS_02406	3854.5146417971	0.552693349039547	0.135906204932038	4.06672638174194	4.7678167966457e-05	0.000379897197322475	1032	rod shape-determining protein MreB	NA	K03569	NA	              Overview	               01200 Carbon metabolism	COG1077	D
LFTS_01668	2993.880962704	0.664933761283246	0.163563250160598	4.06530049158577	4.79706151780751e-05	0.000381006227899983	699	large subunit ribosomal protein L1	NA	K02863	 Translation	              Translation	               03010 Ribosome	COG0081	J
LFTS_00268	289.754815526251	0.982344850070006	0.241771136704291	4.06311879681281	4.84213703159104e-05	0.000383361549698577	1116	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00173	562.68651444539	-0.733493513509189	0.180663918352608	-4.05998895738331	4.90750368173473e-05	0.000387303306437858	204	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00581	11574.1969504001	0.842240783695786	0.208490687976453	4.03970456364416	5.3518572407326e-05	0.000421035351280419	1926	aconitase	Reductive TCA cycle carbon dioxide fixation	K01681	 Carbohydrate metabolism; Overview; Energy metabolism	              Overview	               01200 Carbon metabolism	COG0065;COG1048	EC
LFTS_01691	1787.16137929736	0.562205575540333	0.139445254227125	4.03172971827801	5.53678411246735e-05	0.000434209631028197	624	large subunit ribosomal protein L25	NA	K02897	 Translation	              Translation	               03010 Ribosome	COG1825	J
LFTS_02273	1724.09472955033	0.503949719110872	0.125027741651553	4.03070320597614	5.56102276670329e-05	0.000434739075409572	1086	peptide chain release factor 1	NA	K02835	NA	              Carbohydrate metabolism	               00520 Amino sugar and nucleotide sugar metabolism	COG0216	J
LFTS_02394	4593.09616363567	0.589391787385403	0.146610699188279	4.02011442990596	5.81698800387454e-05	0.00045332389271574	456	LSU ribosomal protein L13P	NA	K02871	 Translation	              Translation	               03010 Ribosome	COG0102	J
LFTS_00964	493.949337124783	0.72910221859942	0.181645476097916	4.01387490766023	5.97300098204524e-05	0.000464027513792639	1005	precorrin-8X methylmutase	NA	K06042	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00860 Porphyrin and chlorophyll metabolism	COG2082	H
LFTS_00591	580.030288532329	0.658417890638779	0.164386260633038	4.00530973880218	6.19362693458041e-05	0.000479668428640713	447	MraZ protein	NA	K03925	NA	              Overview	               01200 Carbon metabolism	COG2001	J
LFTS_01610	1111.40896679282	-0.526064123844074	0.131717702933141	-3.99387563045417	6.50019684795876e-05	0.000501847495777189	1137	3-hydroxybutyryl-CoA dehydrogenase	NA	K00074	 Amino acid metabolism; Carbohydrate metabolism; Xenobiotics biodegradation and metabolism	              Carbohydrate metabolism	               00650 Butanoate metabolism	COG1250	I
LFTS_00228	319.170893074944	-0.699424708867926	0.1752265429316	-3.99154544263849	6.56441061646054e-05	0.000505236061687954	516	purine-binding chemotaxis protein CheW	Chemotaxis	K03408	 Signal transduction; Cell motility	              Signal transduction	               02020 Two-component system	COG0835	NT
LFTS_01940	1880.5329647632	0.948228253251622	0.237715919500227	3.98891355381319	6.63766033956506e-05	0.000509297024819714	219	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01453	1657.11222425592	0.561509520759228	0.140817998639547	3.98748403033713	6.67776978021033e-05	0.000510439183469501	411	transcriptional regulator%2C TraR/DksA family	NA	K06204	 Cellular community - prokaryotes	              Cellular community - prokaryotes	               02026 Biofilm formation - Escherichia coli	COG1734	J
LFTS_01680	863.363460672585	0.53671408471546	0.13461866797978	3.98692167119106	6.69361117502242e-05	0.000510439183469501	1452	SSU ribosomal protein S12P methylthiotransferase	NA	K14441	NA	              Replication and repair	               03440 Homologous recombination	COG0621	J
LFTS_02036	347.302078676575	-0.733622697742258	0.18434581582683	-3.97960048321034	6.90311783235992e-05	0.000524805838876048	1017	lipoprotein	NA	NA	NA	NA	NA	NA	NA
LFTS_01020	706.874540775723	-0.777395683171523	0.195487740985573	-3.97669786991346	6.98788559808981e-05	0.000529630597464978	291	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00779	2611.63041780652	0.469073221401496	0.118123973352764	3.97102474703132	7.15641442881961e-05	0.000539122346962047	1830	GTP-binding protein	NA	K06207	NA	              Metabolism of cofactors and vitamins	               00860 Porphyrin and chlorophyll metabolism	COG1217	T
LFTS_01616	383.637596711928	-0.778734089393473	0.196104189972065	-3.97102218725875	7.1564913313546e-05	0.000539122346962047	732	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_02392	506.657715426353	0.665053081196333	0.167601293187939	3.96806652589834	7.24581091101363e-05	0.000544201991685193	1032	N-acetyl-gamma-glutamyl-phosphate reductase	NA	K00145	 Overview; Amino acid metabolism	              Overview	               01210 2-Oxocarboxylic acid metabolism	COG0002	E
LFTS_00712	1447.14576674925	-0.501306507680471	0.126495565197366	-3.96303622896426	7.40025463583432e-05	0.000554127500743497	1500	hypothetical protein	NA	K09930	NA	              Membrane transport	               03070 Bacterial secretion system	COG3220	S
LFTS_01692	1333.41770876225	0.539275665745673	0.136474762072088	3.95146807774482	7.7673234325607e-05	0.000579866848448826	945	ribose-phosphate pyrophosphokinase	NA	K00948	 Carbohydrate metabolism; Overview; Nucleotide metabolism	              Overview	               01200 Carbon metabolism	COG0462	FE
LFTS_02255	2293.58985416484	0.520351780443359	0.13180324037897	3.9479437603143	7.88253152881395e-05	0.000586705789839266	789	Putative zinc ribbon domain protein	NA	K07164	NA	              Replication and repair	               03030 DNA replication	COG1579	R
LFTS_01217	457.357238294692	-0.779647770715814	0.198284315831663	-3.93196893786451	8.42529542008639e-05	0.000625232370577157	1674	dihydroxyacid dehydratase	NA	K01687	 Metabolism of cofactors and vitamins; Amino acid metabolism; Overview	              Overview	               01210 2-Oxocarboxylic acid metabolism	COG0129	EG
LFTS_01769	728.864035851542	0.547124916695109	0.139533571279821	3.92109878416216	8.81461161516352e-05	0.000652176323669539	675	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01984	2894.5488662756	-0.49472071412499	0.126197094895968	-3.92022268446684	8.84671844863026e-05	0.000652609556774327	1536	proteasome accessory factor A	NA	K13571	NA	              Folding, sorting and degradation	               03050 Proteasome	NA	
LFTS_01337	1994.88835122931	-0.631607993830916	0.16129327667314	-3.91589784062027	9.0068383985331e-05	0.000662455628957198	501	Phosphopantetheine adenylyltransferase	NA	K00954	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00770 Pantothenate and CoA biosynthesis	COG0669	H
LFTS_02259	3213.38406672016	0.531722836750292	0.135948191235302	3.91121670629642	9.18323279455071e-05	0.000673437071600386	483	Yqey-like protein	NA	K09117	NA	              Replication and repair	               03030 DNA replication	COG1610	S
LFTS_02194	680.235242079709	0.549728371931975	0.140615650577233	3.90943945197649	9.25105385727691e-05	0.000676415290858541	456	hypothetical protein	NA	K07007	NA	              Signal transduction	               02020 Two-component system	COG2081	R
LFTS_01880	480.009463288154	0.693883801379575	0.178310031154895	3.89144568527842	9.96486979462932e-05	0.00072647115276975	672	signal peptidase I	NA	K03100	 Cellular community - prokaryotes; Folding, sorting and degradation	              Folding, sorting and degradation	               03060 Protein export	COG0681	U
LFTS_01885	318.872945091949	-0.728095316812478	0.187341911742451	-3.88645183579331	0.000101720097359198	0.000739403982558378	948	transcriptional regulator%2C AraC family	NA	K07506	NA	              Carbohydrate metabolism	               00500 Starch and sucrose metabolism	COG2207	K
LFTS_01277	634.459645445514	0.981109752476687	0.253038615419555	3.87731236534764	0.000105616723224503	0.00076549030302074	657	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01938	411.200016242464	0.745098310605492	0.192803540447814	3.86454682769255	0.000111295637545573	0.000804305101564811	984	ABC-2 type transport system ATP-binding protein	NA	K09687	NA	NA	NA	NA	
LFTS_01756	369.08177422223	-0.915841476245994	0.237793214138657	-3.85141972853761	0.000117435024271812	0.000846212957506445	1287	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01696	648.65229298356	-0.619967085478248	0.161184369180553	-3.84632262191493	0.000119903861465771	0.000861505779202045	552	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase	NA	K00995	 Lipid metabolism	              Lipid metabolism	               00564 Glycerophospholipid metabolism	COG0558	I
LFTS_00169	1068.01172649622	0.628946079488395	0.163567168503076	3.84518534645031	0.000120461350901429	0.000863017055737617	384	transcriptional regulator%2C TraR/DksA family	NA	K06204	 Cellular community - prokaryotes	              Cellular community - prokaryotes	               02026 Biofilm formation - Escherichia coli	COG1734	J
LFTS_01009	661.201210914541	0.619373851846861	0.161840615994994	3.82706064258936	0.000129682574146798	0.000926410572784308	468	hypothetical protein	NA	K08326	NA	              Metabolism of cofactors and vitamins	               00860 Porphyrin and chlorophyll metabolism	COG0006	E
LFTS_02390	3392.80629664101	0.447817883797569	0.117473159487798	3.81208682689839	0.000137798450387362	0.000981567185280747	825	SSU ribosomal protein S2P	NA	K02967	 Translation	              Translation	               03010 Ribosome	COG0052	J
LFTS_02272	651.304248743482	0.613698783567364	0.161096570035359	3.80950869054917	0.000139243212507111	0.000989024646550506	882	release factor glutamine methyltransferase	NA	K02493	NA	              Carbohydrate metabolism	               00520 Amino sugar and nucleotide sugar metabolism	COG2890	J
LFTS_02309	93.7788781665111	-0.95326602542375	0.251469233664364	-3.79078590065644	0.000150171362124734	0.00106360685539056	1368	transposase%2C IS5 family	NA	K07481	NA	              Carbohydrate metabolism	               00500 Starch and sucrose metabolism	COG3039	X
LFTS_01666	1980.14619190021	0.667156250847742	0.176812661731042	3.77323798146641	0.000161142443284268	0.00113806850569514	387	large subunit ribosomal protein L7/L12	NA	K02935	 Translation	              Translation	               03010 Ribosome	COG0222	J
LFTS_00336	4034.45837146629	-0.56299186299618	0.149605153588606	-3.76318495380402	0.000167763033513661	0.00118146997539649	1518	proteasome accessory factor A	NA	K13571	NA	              Folding, sorting and degradation	               03050 Proteasome	NA	
LFTS_00660	691.506710581597	0.567898042254855	0.150997405453187	3.76097880987045	0.000169249768923399	0.00118857323599878	978	phospholipid/cholesterol/gamma-HCH transport system substrate-binding protein	NA	K02067	 Membrane transport	              Membrane transport	               02010 ABC transporters	COG1463	M
LFTS_02151	1170.02475807871	0.955802655519236	0.254566855960372	3.7546233264083	0.000173602352318742	0.00121570548694195	1020	6-phosphogluconate dehydrogenase (decarboxylating)	NA	K00033	 Carbohydrate metabolism; Metabolism of other amino acids; Overview	              Overview	               01200 Carbon metabolism	COG0362;COG1023	G
LFTS_01863	509.21389573506	0.598647918595947	0.159651808514162	3.74970959720035	0.000177039471494808	0.00123629248914633	294	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00832	870.282522440438	0.490463541230241	0.130983726105114	3.74446166569307	0.00018078097495929	0.00125888376400223	3084	hydrophobic/amphiphilic exporter-1%2C HAE1 family	NA	K03296	NA	              Immune system	               04621 NOD-like receptor signaling pathway	COG0841	V
LFTS_00509	272.020838594131	0.682486794907304	0.182385029116971	3.74201105327344	0.000182553483718807	0.00126767586738814	324	putative membrane protein	NA	K00389	NA	              Replication and repair	               03030 DNA replication	COG2149	S
LFTS_01504	1236.14808845351	0.546364897914472	0.146498653983808	3.72948749395922	0.000191869628454458	0.0013286570928629	276	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_02484	470.196042335877	0.581807477710382	0.156042529107093	3.72851863552586	0.000192608667687034	0.00133006985519435	798	myo-inositol-1(or 4)-monophosphatase	NA	K01092	 Biosynthesis of other secondary metabolites; Signal transduction; Carbohydrate metabolism	              Carbohydrate metabolism	               00562 Inositol phosphate metabolism	COG0483	G
LFTS_00880	2334.33793036781	0.49223053873704	0.132067875354816	3.72710272967293	0.000193693524779163	0.00133385623989197	1461	RNA polymerase%2C sigma 54 subunit%2C RpoN/SigL	NA	K03092	 Cellular community - prokaryotes; Signal transduction	              Signal transduction	               02020 Two-component system	COG1508	K
LFTS_02424	1741.5111579917	0.506184787466734	0.136066770074115	3.72012054957296	0.000199127709158274	0.00136749028996538	1590	1%2C4-alpha-glucan branching enzyme	NA	K16150	 Carbohydrate metabolism	              Carbohydrate metabolism	               00500 Starch and sucrose metabolism	COG0438	M
LFTS_02171	2890.59694731325	-0.632265920663286	0.170584978475736	-3.70645719402086	0.000210178740413827	0.00143940591919773	795	undecaprenyl diphosphate synthase	NA	K00806	 Metabolism of terpenoids and polyketides	              Metabolism of terpenoids and polyketides	               00900 Terpenoid backbone biosynthesis	COG0020	I
LFTS_01811	1238.56885953206	0.793689690218475	0.214558055434952	3.69918383446152	0.000216293896910642	0.00147721601021938	1419	alpha-1%2C2-rhamnosyltransferase	Lipopolysaccharide synthesis	K12993	NA	              Glycan biosynthesis and metabolism	               00550 Peptidoglycan biosynthesis	COG0438	M
LFTS_00790	395.97133595555	0.717318039425044	0.194108005728332	3.69545829258059	0.0002194905106498	0.00148776926869036	510	putative rRNA maturation factor	NA	K07042	NA	              Cell growth and death	               04112 Cell cycle - Caulobacter	COG0319	J
LFTS_01720	64.295749550155	-1.05828211832762	0.286382578933402	-3.69534390768135	0.000219589354205855	0.00148776926869036	237	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01157	148.560682230585	-1.12093653778728	0.303341827537907	-3.69529170073719	0.000219634481741497	0.00148776926869036	1653	mercuric reductase	Mercury resistance	K00520	NA	              Signal transduction	               02020 Two-component system	COG1249	C
LFTS_02388	1356.91980577009	0.505473256452007	0.137258823672478	3.68262850378312	0.000230841438879994	0.00155943428547735	711	uridylate kinase	NA	K09903	 Nucleotide metabolism	              Nucleotide metabolism	               00240 Pyrimidine metabolism	COG0528	F
LFTS_02269	1069.3004543105	0.462460303632279	0.125752628355776	3.67753986281621	0.000235494281995813	0.00158655497301244	1338	histidinol dehydrogenase	NA	K00013	 Overview; Amino acid metabolism	              Overview	               01230 Biosynthesis of amino acids	COG0141	E
LFTS_01346	336.014828529383	0.690749214750816	0.187903143523484	3.67609185135579	0.000236834280912033	0.00159127033066842	1137	lipopolysaccharide export system permease protein	Lipopolysaccharide synthesis	K07091	 Membrane transport	              Membrane transport	               02010 ABC transporters	COG0795	MN
LFTS_01216	413.302129172979	-0.838633647427125	0.228260025593583	-3.67402765879081	0.000238756870815622	0.00159986409931978	1017	translation factor SUA5	NA	K07566	NA	              Overview	               01210 2-Oxocarboxylic acid metabolism	COG0009	J
LFTS_02387	1250.30554123856	0.500728735934791	0.136739070508046	3.66192876750122	0.000250323470636018	0.0016728606129063	555	ribosome recycling factor	NA	K02838	NA	              Metabolism of other amino acids	               00473 D-Alanine metabolism	COG0233	J
LFTS_01708	1274.5298255763	0.629833932122561	0.172071944608129	3.66029414938573	0.000251925876172147	0.0016751050164607	1035	glucokinase	NA	K00845	 Overview; Biosynthesis of other secondary metabolites; Carbohydrate metabolism	              Overview	               01200 Carbon metabolism	COG0837	G
LFTS_02249	100406.57768589	-1.55250892267313	0.424158231125426	-3.66021170579157	0.000252006949379044	0.0016751050164607	459	HSP20 family protein	NA	K13993	 Folding, sorting and degradation	              Folding, sorting and degradation	               04141 Protein processing in endoplasmic reticulum	COG0071	O
LFTS_01024	185.08132327015	0.684880684066692	0.187896889471841	3.64498148953834	0.00026741104795566	0.00177275697391406	729	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00440	217.934514494868	0.736712162733268	0.202737154593158	3.6338290542336	0.000279245913773175	0.00184516039633192	1140	cytochrome d ubiquinol oxidase subunit II	Cytochrome bd	K00426	 Energy metabolism; Signal transduction	              Energy metabolism	               00190 Oxidative phosphorylation	COG1294	C
LFTS_00073	460.756776558435	0.710358134496817	0.195513098074206	3.63330202167429	0.000279817163884607	0.00184516039633192	558	hypothetical protein	NA	K07337	NA	              Carbohydrate metabolism	               00620 Pyruvate metabolism	COG3417	M
LFTS_02322	1029.04894890014	0.504019154747229	0.138806473429449	3.63109257295125	0.000282223922431562	0.00185610759567424	549	inorganic pyrophosphatase	NA	K01507	 Energy metabolism	              Energy metabolism	               00190 Oxidative phosphorylation	COG0221	CP
LFTS_01660	2855.53625857283	0.562060129036813	0.154997939435379	3.6262425880258	0.000287575210237428	0.00188267116899939	1200	translation elongation factor 1A (EF-1A/EF-Tu)	NA	K02358	NA	              Membrane transport	               03070 Bacterial secretion system	COG0050	J
LFTS_02056	1715.33856650815	-0.628874841751835	0.173431960535847	-3.62606084719807	0.000287777572091621	0.00188267116899939	222	putative addiction module component	NA	NA	NA	NA	NA	NA	NA
LFTS_00781	759.053365552597	0.57354767779902	0.158986055292653	3.60753448938188	0.000309120457971736	0.00201699070477096	789	phosphoribosyl 1%2C2-cyclic phosphate phosphodiesterase	NA	K06167	 Metabolism of other amino acids	              Metabolism of other amino acids	               00440 Phosphonate and phosphinate metabolism	COG1235	P
LFTS_00438	548.642857840875	-0.550767765360585	0.152736102478683	-3.6060090340295	0.000310942315822211	0.00202356700820423	1365	Transcriptional regulator containing PAS%2C AAA-type ATPase%2C and DNA-binding Fis domains	NA	K02481	NA	              Overview	               01230 Biosynthesis of amino acids	COG2204	T
LFTS_00559	237.566699511332	-0.783166241248864	0.217255614843334	-3.60481473315945	0.000312375685632101	0.00202758734851541	1674	mercuric reductase	Mercury resistance	K00520	NA	              Cellular community - prokaryotes	               02026 Biofilm formation - Escherichia coli	COG1249	C
LFTS_00074	497.807543619349	0.550998766841062	0.15317634756721	3.59715305654026	0.000321719191387149	0.00208279664007409	669	DNA-binding response regulator%2C OmpR family%2C contains REC and winged-helix (wHTH) domain	NA	K02483	NA	              Replication and repair	               03430 Mismatch repair	COG0745	TK
LFTS_01833	508.221154017944	-0.664676614197944	0.185504314258636	-3.58307900737678	0.000339567845426977	0.0021926380876142	381	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00694	2814.27226075105	0.433050502584724	0.121175154634007	3.57375655011701	0.000351896128047224	0.00226635692830415	1014	NADH dehydrogenase subunit H	NADH dehydrogenase	K00337	 Energy metabolism	              Energy metabolism	               00190 Oxidative phosphorylation	COG1005	C
LFTS_01475	635.836814099965	0.506115644324115	0.141648816971443	3.57303121300442	0.000352872680825835	0.00226677386184244	1164	hypothetical protein	NA	K12571	 Folding, sorting and degradation	              Folding, sorting and degradation	               03018 RNA degradation	NA	
LFTS_02389	1977.98375328049	0.494026849423831	0.138558923241947	3.56546397637039	0.000363213051315202	0.00232718465352988	597	translation elongation factor Ts (EF-Ts)	NA	K02357	NA	              Nucleotide metabolism	               00240 Pyrimidine metabolism	COG0264	J
LFTS_00708	242.231077144186	0.658816171439742	0.184859444906429	3.56387617507571	0.000365418385394746	0.00233529590254843	474	hypothetical protein	NA	K02503	NA	              Translation	               03010 Ribosome	COG0537	FGR
LFTS_01987	2195.39498839768	-0.517573253472937	0.145577488948452	-3.55531103889425	0.000377532197624027	0.00240351554862086	750	cob(II)yrinic acid a%2Cc-diamide reductase	NA	K04719	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00740 Riboflavin metabolism	COG0778	C
LFTS_00086	946.121353641842	-0.652486264101363	0.183542152712114	-3.55496682620252	0.000378026781782283	0.00240351554862086	648	thiamine-phosphate pyrophosphorylase	NA	K00788	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00730 Thiamine metabolism	COG0352	H
LFTS_00673	596.329500608128	0.634791052240029	0.178605277348401	3.55415619103885	0.000379193941609667	0.00240478606847355	276	hypothetical protein	NA	K05589	NA	              Energy metabolism	               00190 Oxidative phosphorylation	COG2919	D
LFTS_01422	128.627113145163	0.775776907809032	0.218624010626839	3.54845245764509	0.000387501945763831	0.00245122095971726	444	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_02099	963.974634857161	-0.562921665990525	0.158726553076288	-3.54648705639043	0.000390403920293806	0.00246331001484873	684	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01858	1051.04361221396	-0.52061554343669	0.146975036537126	-3.54220387150701	0.000396798669679968	0.00249732023499848	1167	small ribosomal subunit Rsm22	NA	K02493	NA	              Biosynthesis of other secondary metabolites	               00965 Betalain biosynthesis	COG2890	J
LFTS_00994	5125.6880491013	-0.457046513914824	0.129066905910328	-3.54115960781122	0.000398372514755727	0.00250089412041095	1230	transposase%2C IS605 OrfB family%2C central region	NA	K07496	NA	              Replication and repair	               03430 Mismatch repair	COG0675	X
LFTS_01620	1256.74257420648	-0.614754807129193	0.1738338986498	-3.53644951821312	0.000405543999003013	0.00253950222045715	1131	membrane fusion protein%2C multidrug efflux system	Cadmium/cobalt/zinc resistance	K15727	NA	              Nucleotide metabolism	               00230 Purine metabolism	COG0845	MV
LFTS_02182	460.604076634864	0.534114877964009	0.151207707609417	3.53232574191044	0.000411921609080492	0.00257295758837714	645	putative lysine decarboxylase	NA	K06966	NA	              Amino acid metabolism	               00330 Arginine and proline metabolism	COG1611	R
LFTS_00945	476.765710348825	-0.737442241607373	0.208813862292571	-3.53157703952688	0.000413089512456532	0.00257378578437829	1623	MFS transporter%2C DHA2 family%2C multidrug resistance protein	NA	K03446	NA	              Folding, sorting and degradation	               03018 RNA degradation	COG0477	GEPR
LFTS_02382	6563.19856106598	0.384464210237886	0.108957844287105	3.52855925843043	0.000417828386350138	0.00259680342116611	1539	cytochrome c biogenesis protein	Cytochrome c	K07399	NA	              Nucleotide metabolism	               00240 Pyrimidine metabolism	COG1333	CO
LFTS_02183	882.211151994241	0.455850396785254	0.12926168703829	3.52657007060586	0.000420979752347994	0.0026098644995938	1359	microcin-processing peptidase 1. Unknown type peptidase. MEROPS family U62	NA	K03592	NA	              Amino acid metabolism	               00330 Arginine and proline metabolism	COG0312	R
LFTS_02120	1277.98294453192	0.491982844117923	0.139554117820924	3.52539109415057	0.000422858004627876	0.00261498756095746	561	1%2C2-dihydroxy-3-keto-5-methylthiopentene dioxygenase	NA	K08967	 Amino acid metabolism	              Amino acid metabolism	               00270 Cysteine and methionine metabolism	COG1791	E
LFTS_01739	83.2190942357666	-0.916559705885201	0.260070183602152	-3.52427830514907	0.000424637988251068	0.00261947900444704	1092	Putative MetA-pathway of phenol degradation	NA	NA	NA	NA	NA	NA	NA
LFTS_00067	1152.17112396868	0.668542317316619	0.189998543881942	3.51867074166646	0.000433714625367823	0.00266251306727617	876	F-type H+-transporting ATPase subunit gamma	ATP synthase	K02115	 Energy metabolism	              Energy metabolism	               00190 Oxidative phosphorylation	COG0224	C
LFTS_00575	1150.65812458835	-0.512316401559582	0.14560046612288	-3.51864533955002	0.000433756151346279	0.00266251306727617	2244	PAS domain S-box-containing protein/diguanylate cyclase (GGDEF) domain-containing protein	NA	K14051	 Cellular community - prokaryotes	              Cellular community - prokaryotes	               02024 Quorum sensing	COG2199;COG2200;COG2202	T
LFTS_00911	59.6489490996502	-1.08893315564639	0.309581652374173	-3.51743440638486	0.000435740029556067	0.00266810274255267	1353	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00254	2698.93908173271	-0.447122243965336	0.127433768829373	-3.508663740174	0.000450363914546789	0.00275087147804255	2553	DNA topoisomerase-1	NA	K03168	NA	              Cellular community - prokaryotes	               02024 Quorum sensing	COG0550;COG0551;COG1754	LS
LFTS_01973	8158.16227091404	0.456126447439761	0.130138930668791	3.50491928199887	0.000456745739519304	0.00278301448148282	201	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01690	1781.34455417282	0.568278278490152	0.162624935114428	3.49441048563858	0.000475109904064524	0.00288783183741909	564	peptidyl-tRNA hydrolase%2C PTH1 family	NA	K01056	NA	              Translation	               03010 Ribosome	COG0193	J
LFTS_00520	379.699120592964	-0.604488288744908	0.173086878409044	-3.49239811995663	0.000478704170760873	0.00289927405864641	1518	Lactonase%2C 7-bladed beta-propeller	NA	K07404	 Carbohydrate metabolism; Overview	              Overview	               01200 Carbon metabolism	COG2706	G
LFTS_01291	1513.50496216614	0.496462542611394	0.14216928579539	3.49205202680629	0.000479324874538888	0.00289927405864641	603	periplasmic chaperone for outer membrane proteins Skp	NA	K06142	NA	              Glycan biosynthesis and metabolism	               00540 Lipopolysaccharide biosynthesis	COG2825	MO
LFTS_01384	189.254552144093	-0.70630703272644	0.202353796462982	-3.49045604813078	0.000482196921132567	0.00290286800498188	1137	ABC-2 type transport system permease protein	NA	K09686	NA	NA	NA	NA	
LFTS_00875	1615.37355641051	0.463214465567569	0.132710077827927	3.49042418743946	0.00048225441917036	0.00290286800498188	1374	outer membrane protein	NA	K12340	 Drug resistance; Signal transduction; Membrane transport; Infectious diseases; Environmental adaptation	              Membrane transport	               03070 Bacterial secretion system	COG1538	M
LFTS_02465	1079.41022003388	0.509130564618732	0.145930916947369	3.48884647111724	0.000485109688445688	0.00291300165573908	870	peptidyl-prolyl cis-trans isomerase C	NA	K03769	NA	              Glycan biosynthesis and metabolism	               00540 Lipopolysaccharide biosynthesis	COG0760	O
LFTS_01204	41.94323966099	-1.33016541426507	0.381384794806122	-3.48772534296041	0.000487148221968198	0.00291637554696628	1122	sulfoxide reductase catalytic subunit YedY	NA	K07147	NA	              Translation	               00970 Aminoacyl-tRNA biosynthesis	COG2041	C
LFTS_02496	1273.82888708152	0.558666581896146	0.160202690376409	3.48724843873416	0.000488017790642789	0.00291637554696628	1104	tRNA-specific 2-thiouridylase	NA	K00566	 Folding, sorting and degradation	              Folding, sorting and degradation	               04122 Sulfur relay system	COG0482	J
LFTS_00351	224.279935995695	0.802627712654228	0.230594550717248	3.480688117554	0.000500127480902411	0.00298157534178272	1464	MFS transporter%2C MHS family%2C proline/betaine transporter	NA	K03762	NA	              Membrane transport	               03070 Bacterial secretion system	COG0477	GEPR
LFTS_00137	677.635661382927	-0.527867346685389	0.151697370265668	-3.47973960102891	0.000501901351650611	0.00298499224929048	1389	dihydrolipoamide dehydrogenase	NA	K00382	 Carbohydrate metabolism; Amino acid metabolism; Overview	              Overview	               01200 Carbon metabolism	COG1249	C
LFTS_00517	2663.47890827178	-0.449427125864727	0.12919470309118	-3.47868074395853	0.000503888504377827	0.00298965828611761	1131	two-component system%2C response regulator RpfG	Quorum sensing	K13815	 Cellular community - prokaryotes; Signal transduction	              Signal transduction	               02020 Two-component system	COG3437	T
LFTS_02258	3824.30033679727	0.447994964446934	0.128829866244413	3.47741542785591	0.000506272737181815	0.00299665243960474	1386	DNA primase	NA	K02316	 Replication and repair	              Replication and repair	               03030 DNA replication	COG0358	L
LFTS_01381	65.5012360899508	-1.0763645086389	0.310000663353981	-3.47213614639858	0.00051633440966683	0.00304341063452166	414	outer membrane transport energization protein ExbD	NA	K03559	NA	              Membrane transport	               03070 Bacterial secretion system	COG0848	U
LFTS_01452	1163.22772077965	0.577885888509273	0.166442397366282	3.47198729202119	0.00051662079153988	0.00304341063452166	678	endonuclease-3	NA	K10773	 Replication and repair	              Replication and repair	               03410 Base excision repair	COG0177	L
LFTS_01652	2784.85148361825	0.642183610966305	0.185209933921726	3.46732811447201	0.000525659809743762	0.00308933874000708	681	SSU ribosomal protein S3P	NA	K02982	 Translation	              Translation	               03010 Ribosome	COG0092	J
LFTS_00349	900.746171256569	1.41205290942469	0.408193769301112	3.45927110019914	0.000541639437235406	0.00316902666246981	1278	diaminobutyrate-2-oxoglutarate transaminase	NA	K00836	 Overview; Amino acid metabolism	              Overview	               01210 2-Oxocarboxylic acid metabolism	COG0160;COG4992	E
LFTS_01908	2053.09697200372	0.45332401849272	0.131048538921999	3.459206964242	0.000541768435860688	0.00316902666246981	3474	PAS domain S-box-containing protein/diguanylate cyclase (GGDEF) domain-containing protein	Genes encoding proteins with EAL and GGDEF domains	K14051	 Cellular community - prokaryotes	              Cellular community - prokaryotes	               02024 Quorum sensing	COG2199;COG2200;COG2202	T
LFTS_00757	533.534690448347	-0.603515195246165	0.174571574347568	-3.45712179947797	0.000545978017801722	0.00318615340904949	1689	Galactose oxidase%2C central domain	NA	K10454	NA	              Energy metabolism	               00190 Oxidative phosphorylation	NA	
LFTS_01648	2772.52770928872	0.581436176664807	0.168625197238651	3.44809782989854	0.000564549515742364	0.00328681521343213	540	large subunit ribosomal protein L6	NA	K02933	 Translation	              Translation	               03010 Ribosome	COG0097	J
LFTS_00255	798.703905424536	-0.494540977644529	0.14358455878254	-3.44424903233164	0.00057264799064098	0.00332617501105952	1431	methylenetetrahydrofolate--tRNA-(uracil-5-)- methyltransferase	NA	K04094	NA	              Cellular community - prokaryotes	               02024 Quorum sensing	COG1206	J
LFTS_02134	640.064420745046	0.602210993358368	0.175491185427106	3.43157402403273	0.000600089332822686	0.00347744074917762	297	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00849	4902.93288314674	0.431509507454257	0.126107573644911	3.42175727422434	0.000622178303382315	0.00359705874932194	1299	carboxyl-terminal processing protease	NA	K03797	NA	              Glycan biosynthesis and metabolism	               00550 Peptidoglycan biosynthesis	COG0793	O
LFTS_00276	171.583655060834	0.742495003216398	0.217833903119973	3.40853738826626	0.000653121344581871	0.00376719179264624	660	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00897	776.384954805613	0.45771690501493	0.134427492747602	3.40493522314165	0.000661797500988082	0.00380839950800086	447	biopolymer transport protein TolR	NA	K03560	NA	              Membrane transport	               02010 ABC transporters	COG0848	U
LFTS_00442	605.052109798251	0.774980318174863	0.228104737813533	3.39747576312237	0.000680106122196165	0.00390472013805927	1275	sulfide:quinone oxidoreductase	NA	K03885	 Energy metabolism	              Energy metabolism	               00190 Oxidative phosphorylation	COG1252	C
LFTS_01638	3848.16712521019	0.568823227074613	0.167458491618497	3.39680133014993	0.000681784463508509	0.00390533681171003	975	DNA-directed RNA polymerase subunit alpha	NA	K03040	 Nucleotide metabolism; Transcription	              Nucleotide metabolism	               00230 Purine metabolism	COG0202	K
LFTS_02498	1025.61966781801	0.660469185848822	0.195242000880753	3.38282328018249	0.000717447823760952	0.00410017308016029	855	chromosome partitioning protein%2C ParB family	NA	K03497	NA	              Folding, sorting and degradation	               04122 Sulfur relay system	COG1475	D
LFTS_01647	1236.32751134947	0.647491068683171	0.19146499384397	3.38177259290974	0.000720197379189569	0.00410273028952492	354	large subunit ribosomal protein L18	NA	K02881	 Translation	              Translation	               03010 Ribosome	COG0256	J
LFTS_02122	2815.98496019027	0.531776896385175	0.157265678536865	3.38139193072898	0.000721195951939819	0.00410273028952492	1017	cytochrome c peroxidase	Oxidative stress response	K00428	NA	              Cell growth and death	               04214 Apoptosis - fly	COG1858	O
LFTS_01985	4266.94183517524	-0.384558907554058	0.113856658193864	-3.3775706546671	0.000731291633632491	0.00415066438632505	1728	proteasome-associated ATPase	NA	K13527	 Folding, sorting and degradation	              Folding, sorting and degradation	               03050 Proteasome	COG0464	MDT
LFTS_02275	3074.3883693629	0.392627249806862	0.116279960459282	3.37656848399386	0.000733960978954064	0.0041563257259221	1251	hypothetical protein	NA	K03628	 Folding, sorting and degradation	              Folding, sorting and degradation	               03018 RNA degradation	COG1158	K
LFTS_01923	1184.6557812862	-0.51303426502722	0.152152080667241	-3.37185178656369	0.000746646171758402	0.00421855087043497	573	Diadenosine tetraphosphate (Ap4A) hydrolase	NA	K02503	NA	              Nucleotide metabolism	               00240 Pyrimidine metabolism	COG0537	FGR
LFTS_00417	2596.29193719056	-0.49454076137164	0.147169232300683	-3.36035429172613	0.000778425790461957	0.00438813268727534	1812	molecular chaperone HscA	NA	K04044	NA	              Amino acid metabolism	               00310 Lysine degradation	COG0443	O
LFTS_01746	268.705506233813	-0.582479162282625	0.173830464874742	-3.35084625530022	0.000805650183002362	0.00453132659489564	1452	hypothetical protein	NA	K05844	NA	              Folding, sorting and degradation	               04122 Sulfur relay system	COG0189	HJ
LFTS_01545	754.22780463829	0.591973299606505	0.17696450716759	3.34515270367686	0.000822372793046017	0.004608216390086	546	cation transport protein ChaC	NA	K07232	NA	              Replication and repair	               03410 Base excision repair	COG3703	P
LFTS_00648	1687.21097690152	0.456866727509424	0.136584767920033	3.34493175532507	0.000823028188736196	0.004608216390086	813	adenylyltransferase and sulfurtransferase	NA	K11996	 Folding, sorting and degradation	              Folding, sorting and degradation	               04122 Sulfur relay system	COG0476;COG0607	HP
LFTS_00109	1080.49705632583	0.50996943175172	0.152718387508602	3.33927983441414	0.000839959038061366	0.00469244532274282	1407	hypothetical protein	NA	K02498	NA	              Carbohydrate metabolism	               00500 Starch and sucrose metabolism	COG3071	S
LFTS_01485	1406.24777679841	0.422087626320949	0.126468839808935	3.33748318525436	0.000845408370377123	0.00471229867434423	795	Putative negative regulator of RcsB-dependent stress response	NA	K05807	NA	              Energy metabolism	               00190 Oxidative phosphorylation	COG4105	M
LFTS_02121	1495.97285366807	0.566055569917433	0.170097089081719	3.32783807749636	0.000875227212437529	0.00486759474299709	603	peroxiredoxin (alkyl hydroperoxide reductase subunit C)	Oxidative stress response	K03386	 Cell growth and death	              Cell growth and death	               04214 Apoptosis - fly	COG0450	V
LFTS_00239	128.319542297858	1.42470764215418	0.428402355158687	3.32562980804912	0.000882190110403254	0.00489536744299663	1077	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00360	2192.83069259713	0.406902043613606	0.122438240886345	3.32332480986327	0.000889512753577338	0.00492500825254624	2199	ribonucleoside-diphosphate reductase class II	NA	K00525	 Nucleotide metabolism	              Nucleotide metabolism	               00230 Purine metabolism	COG0209	F
LFTS_00390	453.696992195244	-0.752949588805195	0.226774402534205	-3.320258284846	0.000899342010320131	0.00496836497256855	306	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00850	7318.43827704083	-0.555041050204456	0.167473294384437	-3.31420631715976	0.000919036671255963	0.00506590945619141	264	chaperonin GroES	NA	K04078	NA	              Immune system	               04621 NOD-like receptor signaling pathway	COG0234	O
LFTS_01388	1115.39806532794	-0.466642832683541	0.140832560258714	-3.31345842059749	0.000921498073186665	0.00506823940252666	333	cytochrome c	Cytochrome c	K12263	NA	              Energy metabolism	               00920 Sulfur metabolism	COG2010	C
LFTS_01000	103.060457742431	0.783063274935357	0.236395910178951	3.31250770938711	0.000924635776098916	0.00507427050636182	333	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00881	1259.81488035259	0.497225095995574	0.150407969385183	3.30584275572672	0.000946912112896468	0.00518507381643308	531	putative sigma-54 modulation protein	NA	K05808	NA	              Nucleotide metabolism	               00230 Purine metabolism	COG1544	J
LFTS_00838	5917.97928735747	0.529591136333248	0.160801587474752	3.29344470194613	0.000989678069965079	0.00540343316493463	1776	SSU ribosomal protein S1P	NA	K02945	 Translation	              Translation	               03010 Ribosome	COG0539	J
LFTS_00730	493.051801293616	-0.634525838857634	0.192687496653176	-3.29303068376946	0.000991136574099031	0.00540343316493463	810	Cytochrome c	Cytochrome c	K03889	 Energy metabolism	              Energy metabolism	               00190 Oxidative phosphorylation	COG2010	C
LFTS_01910	116.889587715165	-0.825955554713362	0.25149294931471	-3.28420958505596	0.00102268838504486	0.00556324578823088	900	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01276	969.0618380516	0.834205170068665	0.254400603704741	3.27910059143118	0.00104138508311573	0.00565258366075484	1101	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01334	534.844394600587	-0.502370570706148	0.153311800655579	-3.27678997023029	0.001049944395591	0.00568662694431203	615	translation factor SUA5	NA	K07566	NA	              Membrane transport	               02010 ABC transporters	COG0009	J
LFTS_00116	3571.85719674068	-0.537969143455869	0.164469270240778	-3.27094017422403	0.0010719058384222	0.00579295198764696	933	branched-chain amino acid aminotransferase	NA	K00826	 Metabolism of cofactors and vitamins; Amino acid metabolism; Overview	              Overview	               01210 2-Oxocarboxylic acid metabolism	COG0115	EH
LFTS_00069	743.131407907801	0.596413512955365	0.183196879950344	3.25558772134669	0.00113157934488283	0.00610218275787141	432	F-type H+-transporting ATPase subunit epsilon	ATP synthase	K02114	 Energy metabolism	              Energy metabolism	               00190 Oxidative phosphorylation	COG0355	C
LFTS_01386	138.837382986165	-0.737328910143119	0.226577383212124	-3.25420348531796	0.00113710797674288	0.00611872387485456	906	HlyD family secretion protein	NA	K01993	NA	              Membrane transport	               03070 Bacterial secretion system	COG0845	MV
LFTS_00879	869.234406112263	0.422486420133439	0.1300634448967	3.24831024173617	0.00116092614636075	0.00622211993390633	747	lipopolysaccharide export system ATP-binding protein	NA	K06861	 Membrane transport	              Membrane transport	               02010 ABC transporters	COG1137	M
LFTS_02391	570.503395982813	0.558985501330061	0.17209023861338	3.24821155362498	0.00116132890158187	0.00622211993390633	1215	glutamate N-acetyltransferase	NA	K00620	 Overview; Amino acid metabolism	              Overview	               01210 2-Oxocarboxylic acid metabolism	COG1364	E
LFTS_00274	63104.6526877278	0.485787908714367	0.149659349799994	3.2459576322066	0.00117056258760738	0.00625810450062787	1617	cytochrome	NA	NA	NA	NA	NA	NA	NA
LFTS_00857	4348.46032565523	0.379973632347226	0.117194848507693	3.24223835079479	0.00118594791067421	0.0063267521586611	465	S-adenosylmethionine decarboxylase	Spermidine	K01611	 Amino acid metabolism	              Amino acid metabolism	               00270 Cysteine and methionine metabolism	COG1586	E
LFTS_00018	90.4593390786974	-0.866694806023601	0.267450796741994	-3.24057664655114	0.00119288198427997	0.00635011694415416	969	Permease of the drug/metabolite transporter (DMT) superfamily protein	NA	K03298	NA	              Metabolism of cofactors and vitamins	               00130 Ubiquinone and other terpenoid-quinone biosynthesis	COG0697	GER
LFTS_00834	457.981242787601	0.520418468670173	0.160727151573831	3.23790015298763	0.00120412943635193	0.00638779193792049	441	Fur family transcriptional regulator%2C ferric uptake regulator	NA	K03711	NA	              Immune system	               04621 NOD-like receptor signaling pathway	COG0735	P
LFTS_00533	140.782123700216	-0.784729993826777	0.242374865305543	-3.23767067528858	0.00120509831813544	0.00638779193792049	2046	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_02143	6912.33305916763	0.450098595046778	0.139330519522608	3.23043792981584	0.00123600738681849	0.00652546576355387	2400	phosphoenolpyruvate synthase	Reductive TCA cycle carbon dioxide fixation	K01007	 Energy metabolism; Overview; Carbohydrate metabolism	              Overview	               01200 Carbon metabolism	COG0574	G
LFTS_02096	376.747636970319	-0.519161857349423	0.160713045722936	-3.23036536961934	0.00123632114828394	0.00652546576355387	342	Septum formation initiator	NA	K05589	NA	              Overview	               01210 2-Oxocarboxylic acid metabolism	COG2919	D
LFTS_01027	469.024248663175	-0.574546560679855	0.178030303064499	-3.22724025511377	0.00124990463557752	0.00657105704495701	1593	hypothetical protein	NA	K10300	NA	              Metabolism of other amino acids	               00410 beta-Alanine metabolism	NA	
LFTS_01473	351.327483931747	-0.568903887978138	0.176286111681324	-3.22716226793042	0.00125024536696085	0.00657105704495701	1170	oxygen-independent coproporphyrinogen-3 oxidase	NA	K02495	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00860 Porphyrin and chlorophyll metabolism	COG0635	H
LFTS_00753	289.848296099529	0.671637506323503	0.208256577866953	3.2250482227389	0.00125951451449491	0.00660580819205557	1320	arsenite efflux membrane protein ArsB (TC 3.A.4.1.1%3B TC 2.A.45.1.1)	Arsenic resistance	K03893	NA	              Energy metabolism	               00190 Oxidative phosphorylation	COG1055	P
LFTS_00618	678.733927102006	0.440215024814937	0.136634935582551	3.2218335884454	0.00127373091033173	0.00666232358747766	1341	Surface antigen	NA	K07277	NA	              Overview	               01230 Biosynthesis of amino acids	COG4775	M
LFTS_00098	423.36845993142	-0.546011857063202	0.16949509199685	-3.2214021694112	0.00127565005134327	0.00666232358747766	387	6-pyruvoyltetrahydropterin/6- carboxytetrahydropterin synthase	NA	K01737	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00790 Folate biosynthesis	COG0720	H
LFTS_02393	4128.69379782073	0.456348255503095	0.14193491649796	3.21519374346238	0.00130356508766015	0.00679384236461871	408	SSU ribosomal protein S9P	NA	K02996	 Translation	              Translation	               03010 Ribosome	COG0103	J
LFTS_00551	67.7859332769438	-0.88246179187813	0.274779996188503	-3.21152123196315	0.00132034213555222	0.00686688399368792	1344	sugar transferase%2C PEP-CTERM system associated/exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase	Extracellular polysaccharide production and export	K03606	 Cellular community - prokaryotes	              Cellular community - prokaryotes	               05111 Biofilm formation - Vibrio cholerae	COG2148	M
LFTS_00933	787.106061447033	-0.64169485643905	0.199862730624351	-3.21067792096335	0.00132422263740405	0.0068726878425605	966	protein translocase subunit secF	NA	K12257	 Cellular community - prokaryotes; Folding, sorting and degradation; Membrane transport	              Folding, sorting and degradation	               03060 Protein export	COG0342;COG0341	U
LFTS_00941	1009.96919923499	-0.687006907256731	0.214492831759483	-3.20293644137764	0.00136034000295905	0.00704542759865874	954	membrane fusion protein%2C multidrug efflux system	NA	K03543	NA	              Folding, sorting and degradation	               03018 RNA degradation	COG1566	V
LFTS_00055	648.785187497147	0.442326406049408	0.138142527132034	3.20195681396968	0.00136497459936221	0.00705473358422965	306	preprotein translocase subunit SecG	NA	K03075	 Cellular community - prokaryotes; Folding, sorting and degradation; Membrane transport	              Folding, sorting and degradation	               03060 Protein export	COG1314	U
LFTS_00653	894.992169265409	0.496663093671947	0.155301977627281	3.19804745090832	0.00138361511454335	0.00713623895177337	429	Proteasome lid subunit RPN8/RPN11%2C contains Jab1/MPN metalloenzyme (JAMM) motif	NA	K11865	NA	              Folding, sorting and degradation	               04122 Sulfur relay system	NA	
LFTS_01740	106.386183097071	-0.893728698056123	0.279552343841456	-3.19699948058024	0.00138865176598126	0.00714738776445013	522	Tetratricopeptide repeat-containing protein	NA	K12284	NA	              Folding, sorting and degradation	               04122 Sulfur relay system	NA	
LFTS_00965	10482.2959682782	0.55628804513915	0.174104232538075	3.19514371953878	0.00139761224143062	0.00717864469462089	1011	isocitrate dehydrogenase (NAD+)	Reductive TCA cycle carbon dioxide fixation; Oxidative stress response	K00030	 Carbohydrate metabolism; Overview	              Overview	               01200 Carbon metabolism	COG0473	CE
LFTS_00167	1072.06605596652	-0.513587484168042	0.161012023273806	-3.18974616755589	0.00142397805524109	0.00729898854707084	3111	cobalt-zinc-cadmium resistance protein CzcA	Cadmium/cobalt/zinc resistance	K15726	NA	              Signal transduction	               02020 Two-component system	COG3696	P
LFTS_02007	971.729900612846	0.482476011830463	0.151308722676108	3.18868604068023	0.00142921010576802	0.00731073317477221	645	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01929	702.037896672885	0.633324219887423	0.198807883152043	3.18560919137735	0.00144449582020603	0.00737375073723244	663	hypothetical protein	NA	K07286	NA	              Nucleotide metabolism	               00240 Pyrimidine metabolism	COG3056	S
LFTS_01502	449.3096534397	0.487188838910691	0.153162393186884	3.18086462853998	0.00146836225755038	0.00748022248416034	786	phospholipid/cholesterol/gamma-HCH transport system permease protein	NA	K02066	 Membrane transport	              Membrane transport	               02010 ABC transporters	COG0767	M
LFTS_00796	1261.0271425255	0.500309712637289	0.157616977424769	3.17421207291003	0.00150243871681582	0.00763816492843382	828	Polyphosphate:AMP phosphotransferase	NA	K00947	NA	              Carbohydrate metabolism	               00650 Butanoate metabolism	NA	
LFTS_01889	1219.8169560678	0.464119697054458	0.146303289401139	3.1723121124223	0.00151230380645624	0.00766073725199209	2442	ATP-dependent Lon protease	NA	K01338	 Cell growth and death	              Cell growth and death	               04112 Cell cycle - Caulobacter	COG0466	O
LFTS_01154	47.8115554128099	-1.00160170313253	0.31574649736507	-3.17217043258111	0.00151304183054228	0.00766073725199209	273	Thioredoxin domain-containing protein	NA	K03676	NA	              Signal transduction	               02020 Two-component system	COG0695	O
LFTS_02074	532.816503755013	-0.479122791225331	0.151396152174099	-3.16469596053115	0.00155245082180059	0.00784429419308187	1230	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01264	166.954660640139	-0.747085093705856	0.236577893593795	-3.15788209268869	0.00158919820780893	0.00801368508035094	492	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00495	926.151811944939	0.760141474604992	0.241333574975936	3.14975433766639	0.00163407804506151	0.00822331583000588	1374	glutamate decarboxylase	Proton consuming reactions	K01580	 Metabolism of other amino acids; Cellular community - prokaryotes; Amino acid metabolism; Carbohydrate metabolism; Nervous system; Endocrine and metabolic diseases	              Carbohydrate metabolism	               00650 Butanoate metabolism	COG0076	E
LFTS_01528	2648.96949673815	0.372339894551278	0.118275870429255	3.14806302587296	0.00164356252225803	0.00824367655660769	1332	UDPglucose 6-dehydrogenase	Extracellular polysaccharide production and export	K00012	 Carbohydrate metabolism	              Carbohydrate metabolism	               00040 Pentose and glucuronate interconversions	COG1004	M
LFTS_01840	310.892305402427	-0.709407755449843	0.225362571105645	-3.14785082531423	0.00164475606278255	0.00824367655660769	1398	membrane-bound serine protease (ClpP class)	NA	K07403	NA	              Nucleotide metabolism	               00230 Purine metabolism	COG1030	O
LFTS_02145	239.139943865623	0.556671664129165	0.17733851327777	3.13903423368186	0.00169505644027778	0.0084786927777275	624	hypothetical protein	NA	K08173	NA	              Signal transduction	               02020 Two-component system	COG0477	GEPR
LFTS_00108	1915.75177848967	0.503875772922604	0.161234191262397	3.12511737726015	0.00177734123958896	0.00887243036469508	558	ribosome-associated protein	NA	K09710	NA	              Carbohydrate metabolism	               00500 Starch and sucrose metabolism	COG0799	J
LFTS_01933	813.740144432419	0.529204508628768	0.170193653488674	3.10942563239577	0.00187451466883553	0.00932513934707895	1296	glycerate 2-kinase	NA	K00050	 Carbohydrate metabolism; Amino acid metabolism	              Carbohydrate metabolism	               00630 Glyoxylate and dicarboxylate metabolism	COG2379	G
LFTS_01091	69.2148306510648	0.860821942970801	0.276857005710345	3.10926552413637	0.00187553084213173	0.00932513934707895	285	Homeodomain-like domain-containing protein	NA	K11686	NA	              Amino acid metabolism	               00310 Lysine degradation	COG0789	K
LFTS_01228	233.528594824177	0.569543859390298	0.183418714913037	3.10515674292196	0.00190178215345911	0.00943678729241389	711	Methyltransferase domain-containing protein	NA	K00588	 Biosynthesis of other secondary metabolites; Amino acid metabolism	              Amino acid metabolism	               00360 Phenylalanine metabolism	COG4122	R
LFTS_02366	1720.49991145668	-0.445980097403188	0.143838922790858	-3.10055226186339	0.00193160123440756	0.00956565870266376	741	demethylmenaquinone methyltransferase / 2-methoxy-6-polyprenyl-1%2C4-benzoquinol methylase	NA	K03183	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00130 Ubiquinone and other terpenoid-quinone biosynthesis	COG2226	H
LFTS_02361	4691.21319023157	-0.672164102757513	0.216917887580145	-3.09870297122992	0.00194369780023552	0.00960642690136283	189	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01201	111.300772105103	-0.795588964136992	0.256940929921921	-3.09638859164538	0.00195893458514508	0.00966115003075962	3219	nitrite reductase (NADH) large subunit	Nitrite uptake & assimilation to ammonia	K00362	 Energy metabolism	              Energy metabolism	               00910 Nitrogen metabolism	COG1251	C
LFTS_01639	2562.89146403088	0.489898739212815	0.158244052343569	3.09584298403316	0.00196254254446243	0.00966115003075962	630	SSU ribosomal protein S4P	NA	K02986	 Translation	              Translation	               03010 Ribosome	COG0522	J
LFTS_01380	52.8349088986159	-1.00757160652331	0.325649673042068	-3.09403536969972	0.00197453945028099	0.00970099816877181	654	protein TonB	NA	K03832	NA	              Membrane transport	               03070 Bacterial secretion system	COG0810	M
LFTS_02447	1741.05842155408	0.47416404482609	0.153330357041354	3.09243423139102	0.00198522218536919	0.0097342452718497	402	putative hydrolase of the HAD superfamily protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01803	378.61961799438	0.586125543975341	0.189573666614078	3.09180887010292	0.00198940895928232	0.00973557219050364	312	DNA replication protein DnaC	NA	K02315	NA	              Overview	               01200 Carbon metabolism	COG1484	L
LFTS_00237	230.224731947986	0.78049690362912	0.252665938382781	3.08904678099781	0.00200799818011364	0.00980723669108547	459	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01861	564.748285630264	-0.55765219264022	0.180771609230782	-3.08484388125512	0.00203659024326937	0.00992737910738756	1140	23S rRNA (adenine2503-C2)-methyltransferase	NA	K06941	NA	              Carbohydrate metabolism	               00500 Starch and sucrose metabolism	COG0820	J
LFTS_00256	455.506514854839	-0.587190750116702	0.190510267929713	-3.08220001209247	0.00205476722480226	0.00999638223259963	966	integrase/recombinase XerC	NA	K03733	NA	              Amino acid metabolism	               00330 Arginine and proline metabolism	COG0582	LX
LFTS_00682	1258.84231158686	0.421926434443303	0.137016668336147	3.07938033793216	0.0020743168090543	0.0100717804439629	756	23S rRNA (cytidine1920-2'-O)/16S rRNA (cytidine1409-2'-O)-methyltransferase	NA	K06442	NA	              Carbohydrate metabolism	               00052 Galactose metabolism	COG1189	J
LFTS_01592	687.980700664812	0.430298381549992	0.139908258641305	3.07557527860586	0.00210096885155131	0.0101556092297207	474	acetyl-CoA carboxylase biotin carboxyl carrier protein	NA	K02160	 Carbohydrate metabolism; Overview; Energy metabolism; Lipid metabolism	              Overview	               01200 Carbon metabolism	COG0511	HI
LFTS_02510	596.647651747831	-0.435629137173838	0.141658472501173	-3.07520707714981	0.00210356446651807	0.0101556092297207	672	precorrin-6Y C5%2C15-methyltransferase (decarboxylating)	NA	K00595	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00860 Porphyrin and chlorophyll metabolism	COG2241;COG2242	H
LFTS_01299	518.121614580733	0.446680388930181	0.145253958362688	3.07516844267235	0.00210383698845784	0.0101556092297207	1803	ATP-binding cassette%2C subfamily B%2C MsbA	Lipopolysaccharide synthesis	K11085	 Membrane transport	              Membrane transport	               02010 ABC transporters	COG1132	V
LFTS_00735	187.031353571402	-0.734451997664914	0.238936898186672	-3.07383247727237	0.00211328063500458	0.0101814256950027	1491	C-3'%2C4' desaturase CrtD	NA	K09835	 Metabolism of terpenoids and polyketides	              Metabolism of terpenoids and polyketides	               00906 Carotenoid biosynthesis	COG1233	Q
LFTS_01002	59.8885229865169	0.856896173012728	0.279029764564427	3.07098482611834	0.002133539932311	0.0102591494617507	96	Site-specific recombinase XerD	NA	K03733	NA	              Energy metabolism	               00190 Oxidative phosphorylation	COG0582	LX
LFTS_00077	813.742178292502	-0.789962160429869	0.258430545992809	-3.05676775705861	0.00223737553300103	0.0107376748552906	1491	Outer membrane protein assembly factor BamB%2C contains PQQ-like beta-propeller repeat	NA	K00114	 Carbohydrate metabolism; Xenobiotics biodegradation and metabolism	              Carbohydrate metabolism	               00010 Glycolysis / Gluconeogenesis	COG4993	G
LFTS_00445	994.641116644003	0.622727364996567	0.204125732596156	3.05070486252008	0.00228304871439382	0.0109357593525685	312	hypothetical protein	NA	K01999	 Cellular community - prokaryotes; Membrane transport	              Membrane transport	               02010 ABC transporters	COG0683	E
LFTS_00946	626.308311331348	-0.517805408151588	0.170285790908969	-3.04080220309396	0.00235948777288901	0.011279568574138	1059	heat-inducible transcription repressor HrcA	NA	K03705	NA	              Folding, sorting and degradation	               03018 RNA degradation	COG1420	K
LFTS_01670	1956.75651619286	0.593240970686563	0.195147457814474	3.03996258690981	0.00236607538675822	0.011279568574138	555	transcription antitermination protein nusG	NA	K02601	NA	              Folding, sorting and degradation	               03060 Protein export	COG0250	K
LFTS_00547	83.3359047232515	-0.773010702269361	0.254308103759632	-3.03966209035949	0.00236843716641192	0.011279568574138	1146	Glycosyltransferase%2C catalytic subunit of cellulose synthase and poly-beta-1%2C6-N-acetylglucosamine synthase	Extracellular polysaccharide production and export	K11936	 Cellular community - prokaryotes	              Cellular community - prokaryotes	               02026 Biofilm formation - Escherichia coli	COG1215	N
LFTS_01649	2113.71854073786	0.711239150165594	0.234095853103003	3.03823899799134	0.00237965143158622	0.0113113068048247	399	small subunit ribosomal protein S8	NA	K02994	 Translation	              Translation	               03010 Ribosome	COG0096	J
LFTS_00675	37873.3269209174	-1.26506143313112	0.416739619809857	-3.0356159409761	0.00240044913345589	0.0113883903545255	1383	Recombination protein MgsA	NA	K07478	NA	              Energy metabolism	               00190 Oxidative phosphorylation	COG2256	L
LFTS_01335	20032.2428024271	0.51153318005478	0.168617333494203	3.03369273759964	0.00241580340839616	0.0114264889892539	384	Putative peptidoglycan binding domain-containing protein	NA	K13582	 Cell growth and death	              Cell growth and death	               04112 Cell cycle - Caulobacter	COG0790;COG3409	TM
LFTS_01821	278.567704146082	-0.88964836355712	0.293278478595115	-3.0334594199301	0.00241767224792741	0.0114264889892539	1662	NAD(P)H-quinone oxidoreductase subunit 5	NADH dehydrogenase	K05577	 Energy metabolism	              Energy metabolism	               00190 Oxidative phosphorylation	COG1009	CP
LFTS_01537	504.987841753046	0.443447290137801	0.146356084965993	3.02992041800544	0.00244618185337513	0.0115392942836633	666	cytidylate kinase	NA	K00945	 Nucleotide metabolism	              Nucleotide metabolism	               00240 Pyrimidine metabolism	COG0283	F
LFTS_00190	1321.26954143112	-0.443687247289329	0.146549515469898	-3.02755860957087	0.00246537900502043	0.0116078261486379	1491	glycine dehydrogenase (decarboxylating) beta subunit	NA	K00283	 Carbohydrate metabolism; Overview; Amino acid metabolism	              Overview	               01200 Carbon metabolism	COG1003	E
LFTS_02516	761.181491756904	-0.417607703948947	0.138183706745996	-3.02211971138231	0.00251011258722996	0.011796105655678	756	orotidine-5'-phosphate decarboxylase	NA	K01591	 Nucleotide metabolism	              Nucleotide metabolism	               00240 Pyrimidine metabolism	COG0284	F
LFTS_00240	67.5112229427135	1.19015135378473	0.393958505182198	3.02100687795611	0.00251935637166864	0.0118172074339023	714	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00928	1303.94526122671	-0.593566142824531	0.196861146779525	-3.01515130097914	0.00256851091853734	0.0120250812494988	1038	N6-L-threonylcarbamoyladenine synthase	NA	K01409	NA	              Metabolism of cofactors and vitamins	               00860 Porphyrin and chlorophyll metabolism	COG0533	J
LFTS_01907	9056.41969223747	-0.467337650432526	0.155082160849103	-3.01348425811046	0.00258266439590293	0.0120686159552908	1413	glutamine synthetase	Ammonia & glutamate conversion to glutamine	K01915	 Carbohydrate metabolism; Amino acid metabolism; Energy metabolism; Overview; Signal transduction; Nervous system	              Overview	               01230 Biosynthesis of amino acids	COG0174	E
LFTS_00361	3242.27927707309	0.45026348274565	0.149685095232814	3.00807159220048	0.00262911194314973	0.0122626121776177	420	Rubrerythrin	Oxidative stress response	K02217	NA	              Nucleotide metabolism	               00230 Purine metabolism	COG1528	P
LFTS_02063	123.595290247712	-0.68736153639753	0.228715170647887	-3.00531676342424	0.00265304395138857	0.0123367196170192	435	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00696	1442.87651085442	0.390743163350577	0.130045148760825	3.00467312371044	0.00265866405780738	0.0123367196170192	510	NADH-quinone oxidoreductase subunit J	NADH dehydrogenase	K00339	 Energy metabolism	              Energy metabolism	               00190 Oxidative phosphorylation	COG0839	C
LFTS_02441	370.248376337447	-0.565746812115319	0.188297745872714	-3.00453311054373	0.00265988805901942	0.0123367196170192	327	MerR family transcriptional regulator%2C heat shock protein HspR	NA	K13640	NA	              Amino acid metabolism	               00250 Alanine, aspartate and glutamate metabolism	COG0789	K
LFTS_00729	733.652207884443	-0.497156262679579	0.165561718144951	-3.0028455143496	0.0026746816682905	0.0123822320807638	609	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00174	1230.61691231331	-0.433998246405332	0.14489109396218	-2.99534108368742	0.00274138106970405	0.0126674225637254	1311	GGDEF domain-containing protein%2C diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	Putative diguanylate cyclases (GGDEF domain-containing proteins)	K13069	NA	              Cancers	               05206 MicroRNAs in cancer	COG2199	T
LFTS_00503	2423.11254391864	-0.354747205717434	0.118474201986725	-2.99429917879661	0.00275076070743733	0.0126871820383844	1143	two-component system%2C cell cycle response regulator	Putative diguanylate cyclases (GGDEF domain-containing proteins)	K13590	 Cell growth and death	              Cell growth and death	               04112 Cell cycle - Caulobacter	COG2199	T
LFTS_01976	209.742777777851	0.568085943801909	0.189769962940724	2.99355037540559	0.00275751982606947	0.0126948042363124	720	putative Fe2+/Mn2+ transporter%2C VIT1/CCC1 family	NA	K03968	 Neurodegenerative diseases; Endocrine and metabolic diseases; Energy metabolism	              Energy metabolism	               00190 Oxidative phosphorylation	NA	
LFTS_01294	910.385541931455	0.44856241296606	0.149930170244101	2.99180886832688	0.00277329835595159	0.0127438442012859	864	acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase	Lipopolysaccharide synthesis	K00677	 Glycan biosynthesis and metabolism; Drug resistance	              Glycan biosynthesis and metabolism	               00540 Lipopolysaccharide biosynthesis	COG1043	M
LFTS_02529	513.928682386534	0.501426506407859	0.168213110576608	2.98090026805311	0.00287402374335373	0.0131823303062313	1056	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01582	3483.74963214021	0.44420099548673	0.149212257207231	2.97697390147921	0.00291108789979896	0.0133277431287297	1407	Penicillin binding protein transpeptidase domain-containing protein	NA	K05364	 Glycan biosynthesis and metabolism	              Glycan biosynthesis and metabolism	               00550 Peptidoglycan biosynthesis	COG0768	DM
LFTS_02149	418.0426133964	0.674354238683268	0.226716836802432	2.97443387175926	0.00293529715506844	0.0134138763373164	744	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	NA	K16066	 Nucleotide metabolism; Amino acid metabolism	              Nucleotide metabolism	               00240 Pyrimidine metabolism	COG4221	C
LFTS_02323	1626.02630477857	-0.502006747303238	0.168949461455818	-2.97134269016015	0.0029650072859216	0.0135247855280754	651	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01139	519.241308769197	0.444126343685919	0.149729578968151	2.96618975854056	0.00301514391813294	0.013728292638239	738	CRISPR-associated protein%2C Cas5e family	NA	NA	NA	NA	NA	NA	NA
LFTS_00764	427.174592496676	-0.509080437114117	0.171723725910628	-2.9645317466444	0.00303143962766371	0.0137772557849579	231	SAP domain-containing protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01991	6869.45963202041	0.436004351016024	0.147174641248832	2.96249644175358	0.00305155336452384	0.0138433607011063	1359	glutamyl-tRNA reductase	NA	K02492	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00860 Porphyrin and chlorophyll metabolism	COG0373	H
LFTS_02477	1710.58656713957	-0.550883274090872	0.186078291481341	-2.96049189674612	0.00307148201614334	0.0138917877551566	540	signal peptidase II	NA	K03101	 Folding, sorting and degradation	              Folding, sorting and degradation	               03060 Protein export	COG0597	MU
LFTS_02303	498.4366601579	0.604450802905744	0.204185715615319	2.96029916237879	0.00307340437060988	0.0138917877551566	378	SmpA / OmlA family protein	NA	K06186	NA	              Lipid metabolism	               00564 Glycerophospholipid metabolism	COG2913	M
LFTS_00574	237.487947658923	0.600755886231331	0.203049570736044	2.95866612302416	0.00308973657593796	0.0139402633898036	570	protein-tyrosine phosphatase	NA	K01104	NA	              Cellular community - prokaryotes	               02024 Quorum sensing	COG0394;COG5599;COG2365;COG2453;COG4464	T
LFTS_01034	395.329089645366	0.524405113093639	0.178092828442901	2.94456052879058	0.00323413679160792	0.0145325837715389	1371	DNA methylase	NA	K00590	NA	              Amino acid metabolism	               00270 Cysteine and methionine metabolism	COG0863	L
LFTS_01805	1788.91558933389	0.571207408202584	0.194025297480166	2.94398418979863	0.00324016551275142	0.0145325837715389	1698	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_02140	719.698659589798	-0.508923764798589	0.172880384549836	-2.94379125846913	0.00324218593295825	0.0145325837715389	183	hypothetical protein	NA	K06575	 Immune system; Infectious diseases	              Immune system	               04640 Hematopoietic cell lineage	NA	
LFTS_02104	1047.66215034376	-0.425656347767254	0.144604999485204	-2.94357974677638	0.00324440224988097	0.0145325837715389	2241	DNA helicase-2 / ATP-dependent DNA helicase PcrA	NA	K03657	 Replication and repair	              Replication and repair	               03420 Nucleotide excision repair	COG0210	L
LFTS_01214	769.073671535275	-0.577370457210083	0.196208486310181	-2.94263753860948	0.00325429192132006	0.014550664957557	1470	two-component system%2C NtrC family%2C response regulator AtoC	NA	K07714	 Signal transduction	              Signal transduction	               02020 Two-component system	COG2204	T
LFTS_02232	312.033053264951	0.545232071492849	0.185414559820636	2.94061087770177	0.00327565743925044	0.0146199001687192	1263	putative arabinose efflux permease%2C MFS family	NA	K05820	NA	              Metabolism of cofactors and vitamins	               00770 Pantothenate and CoA biosynthesis	COG0477	GEPR
LFTS_01135	328.845399286899	0.485914107465248	0.165419777701008	2.93746076931337	0.00330912036592833	0.0147427835657667	1533	CRISPR system Cascade subunit CasA	NA	NA	NA	NA	NA	NA	NA
LFTS_00872	775.892114506834	-0.475619126589412	0.162187949768321	-2.93251827443909	0.00336225134502292	0.0149347108499384	4350	PAS domain S-box-containing protein/diguanylate cyclase (GGDEF) domain-containing protein	NA	K13069	NA	              Metabolism of cofactors and vitamins	               00770 Pantothenate and CoA biosynthesis	COG2199	T
LFTS_00260	204.908570644174	-0.641226057849898	0.218674068000629	-2.93233698770378	0.00336421483345354	0.0149347108499384	471	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01937	409.269489311163	0.49396008812935	0.168523644649657	2.93110257113321	0.00337761239105773	0.0149674588309617	822	ABC-2 type transport system permease protein	NA	K09686	NA	NA	NA	NA	
LFTS_00102	2404.82250107682	0.359984797368949	0.123005606067332	2.92657228298925	0.00342719854374347	0.0151463705966925	321	large subunit ribosomal protein L21	NA	K02888	 Translation	              Translation	               03010 Ribosome	COG0261	J
LFTS_01287	490.375081439646	-0.532928942546377	0.182116829053947	-2.92630255707182	0.00343017161944403	0.0151463705966925	261	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00950	808.748007803216	-0.584967578101758	0.199983712605921	-2.92507609984454	0.00344371997375812	0.0151792337850402	864	16S rRNA (uracil1498-N3)-methyltransferase	NA	K09761	NA	              Xenobiotics biodegradation and metabolism	               00983 Drug metabolism - other enzymes	COG1385	J
LFTS_02141	324.500881717905	-0.519830692605748	0.17779364767669	-2.92378664479081	0.00345801675914687	0.0152152737402462	693	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_02412	210.978625592899	-0.734442927870681	0.251259209558804	-2.92304878758601	0.00346622200397785	0.0152244309220652	432	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_02467	1870.79260676031	0.459166165934495	0.157177378806934	2.92132474418283	0.00348546312022322	0.0152819423578041	1023	periplasmic chaperone for outer membrane proteins SurA	NA	K03771	NA	              Replication and repair	               03420 Nucleotide excision repair	COG0760	O
LFTS_01644	2191.72895212114	0.497088227124827	0.170534151527269	2.91488961403336	0.00355814369889272	0.0155731430201537	1314	protein translocase subunit secY/sec61 alpha	NA	K03076	 Cellular community - prokaryotes; Folding, sorting and degradation; Membrane transport	              Folding, sorting and degradation	               03060 Protein export	COG0201	U
LFTS_00365	791.867971761042	0.662524008908778	0.227377790941071	2.9137586664323	0.00357105854608686	0.0155943993657622	318	Outer membrane protein OmpA	NA	NA	NA	NA	NA	NA	NA
LFTS_01370	226.528059934163	-0.539813011396102	0.185288393932952	-2.91336656299928	0.00357554611363011	0.0155943993657622	507	NusB antitermination factor	NA	K03625	NA	              Signal transduction	               02020 Two-component system	COG0781	K
LFTS_01025	1277.52354959496	-0.37534607988054	0.129672870579467	-2.89456135430053	0.00379688700307523	0.0165307549731086	579	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01479	1709.44156032263	0.471017553207317	0.163125072702962	2.88746264079834	0.0038836272305746	0.0168788414251896	849	acyl-[acyl-carrier-protein] desaturase	NA	K03921	 Lipid metabolism; Overview	              Overview	               01212 Fatty acid metabolism	NA	
LFTS_00138	665.508742336722	-0.412931904597933	0.143106597233696	-2.88548475458197	0.00390811389412963	0.0169556215371837	1395	hypothetical protein	NA	K02668	 Signal transduction	              Signal transduction	               02020 Two-component system	COG0642	T
LFTS_02012	180.367683210731	-0.575101994670472	0.19976919454019	-2.87883222432862	0.00399150618691778	0.0172872550186021	900	RND family efflux transporter%2C MFP subunit	NA	K15548	NA	              Metabolism of cofactors and vitamins	               00790 Folate biosynthesis	COG1566	V
LFTS_01662	1817.7618759614	0.450386655222998	0.156550420255429	2.87694312470158	0.00401547962817619	0.0173608388793844	474	small subunit ribosomal protein S7	NA	K02992	 Translation	              Translation	               03010 Ribosome	COG0049	J
LFTS_00706	769.45226416384	0.451435710973053	0.156972935726141	2.87588244995711	0.0040289972514628	0.0173890402207231	813	L-proline dehydrogenase	NA	K00318	 Amino acid metabolism	              Amino acid metabolism	               00330 Arginine and proline metabolism	COG0506	E
LFTS_00161	698.466449806029	0.466160539930486	0.162678714833789	2.86552878418524	0.00416313423410046	0.0179368313795039	249	TusA-related sulfurtransferase	NA	K04085	 Folding, sorting and degradation	              Folding, sorting and degradation	               04122 Sulfur relay system	COG0425	O
LFTS_00856	2593.71994445604	0.437038256678638	0.152588746282942	2.86415785780327	0.0041811958237823	0.0179834823839495	861	spermidine synthase	Spermidine	K00797	 Amino acid metabolism; Metabolism of other amino acids	              Amino acid metabolism	               00270 Cysteine and methionine metabolism	COG0421	E
LFTS_01559	186.284579162776	-0.592759920090435	0.20724533926781	-2.86018456282121	0.00423394522175177	0.0181789081541881	1017	adenosylcobinamide-phosphate synthase	NA	K02227	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00860 Porphyrin and chlorophyll metabolism	COG1270	H
LFTS_01834	720.441031526487	-0.388894215782866	0.136001980121933	-2.85947465937041	0.00424343319546621	0.0181882326274638	564	hypothetical protein	NA	K15017	 Overview; Energy metabolism	              Overview	               01200 Carbon metabolism	COG0136	E
LFTS_01943	7250.8874448147	0.427753315520142	0.149650538802035	2.85834798153313	0.00425853102014091	0.0182215285990883	621	cytochrome b6-f complex iron-sulfur subunit	Cytochrome b/c1	K02636	 Energy metabolism	              Energy metabolism	               00195 Photosynthesis	COG0723	C
LFTS_02324	1581.26849904717	-0.491975408675325	0.172513903108699	-2.85180150590725	0.00434722372429005	0.0185690690353695	207	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00831	1041.38092078405	-0.400822782911295	0.140613420992238	-2.8505300566823	0.00436464249885004	0.0186114944290587	501	Thiol-disulfide isomerase or thioredoxin	NA	K03671	 Cardiovascular diseases; Immune system	              Immune system	               04621 NOD-like receptor signaling pathway	COG0526	O
LFTS_00654	790.498154216886	0.396262441232364	0.139116445000209	2.84842270970746	0.00439365240064692	0.0187031162123429	696	two-component system%2C OmpR family%2C alkaline phosphatase synthesis response regulator PhoP	NA	K07658	 Signal transduction	              Signal transduction	               02020 Two-component system	COG0745	TK
LFTS_01891	577.846473327081	0.405271540277552	0.142625468391565	2.84150891736191	0.00449005962324345	0.0190808345698858	1113	peptide chain release factor 2	NA	K02836	NA	              Membrane transport	               02010 ABC transporters	COG1186	J
LFTS_00663	2470.02141729518	-0.395169151986565	0.139682614938755	-2.8290503593438	0.00466863520016484	0.0198058483065013	3420	PAS domain S-box-containing protein/diguanylate cyclase (GGDEF) domain-containing protein	Genes encoding proteins with EAL and GGDEF domains	K14051	 Cellular community - prokaryotes	              Cellular community - prokaryotes	               02024 Quorum sensing	COG2199;COG2200;COG2202	T
LFTS_01455	749.047726971317	0.402304326387177	0.142578261757591	2.82163859643042	0.00477789871375511	0.0202348487263973	1455	methyl-accepting chemotaxis protein	Chemotaxis	K03406	 Signal transduction; Cell motility	              Signal transduction	               02020 Two-component system	COG0840	NT
LFTS_02408	813.316835388042	-0.401388478680927	0.14234743531631	-2.81978019336282	0.00480565553818314	0.02031778855089	696	ribulose-5-phosphate 3-epimerase	NA	K01783	 Carbohydrate metabolism; Energy metabolism; Overview	              Overview	               01200 Carbon metabolism	COG0036	G
LFTS_00855	987.091642739706	0.372762477623676	0.132339097914461	2.81672221964681	0.00485164669855582	0.0204774086461965	1470	arginine decarboxylase	Proton consuming reactions	K01582	 Amino acid metabolism; Biosynthesis of other secondary metabolites	              Amino acid metabolism	               00310 Lysine degradation	COG1982	E
LFTS_00572	205.975748241288	-0.639970325768647	0.227487356018441	-2.81321272957592	0.00490491904063112	0.0206671673474728	951	UDP-glucose 4-epimerase	Extracellular polysaccharide production and export	K01784	 Carbohydrate metabolism	              Carbohydrate metabolism	               00052 Galactose metabolism	COG1087	M
LFTS_02202	719.186407877363	-0.448227565137331	0.159495482168868	-2.81028377131563	0.0049497836422053	0.0208209173172968	1080	putative glycosyl transferase	NA	K02563	 Cell growth and death; Glycan biosynthesis and metabolism; Drug resistance	              Glycan biosynthesis and metabolism	               00550 Peptidoglycan biosynthesis	COG0707	M
LFTS_02081	514.653482882129	-0.530429352498475	0.189591342695705	-2.79775091497619	0.00514597802391702	0.0216096306882732	1449	competence protein ComEC	NA	K02238	NA	              Carbohydrate metabolism	               00520 Amino sugar and nucleotide sugar metabolism	COG0658;COG2333	R
LFTS_02466	441.514803739552	0.41462848973307	0.148307231130306	2.79574021153944	0.00517810052754389	0.0217078548254201	975	peptidyl-prolyl cis-trans isomerase C	NA	K03771	NA	              Replication and repair	               03420 Nucleotide excision repair	COG0760	O
LFTS_02105	1978.73095079495	-0.419569881412198	0.15039732571543	-2.78974296528433	0.0052749900836162	0.0220768103499493	1320	TolB protein	NA	K03641	NA	              Replication and repair	               03420 Nucleotide excision repair	COG0823	U
LFTS_02177	1146.5810211631	0.366747687515728	0.131625669647059	2.78629304222441	0.00533146502474257	0.0222516673026291	237	hypothetical protein	NA	K09794	NA	              Lipid metabolism	               00564 Glycerophospholipid metabolism	COG2841	S
LFTS_00399	913.983184710974	-0.398366920111809	0.142984803456846	-2.78607873340917	0.00533499118945398	0.0222516673026291	1566	GTP-binding protein HflX	NA	K03665	NA	              Signal transduction	               02020 Two-component system	COG2262	J
LFTS_00936	3990.3486891077	-0.313157671208957	0.112422014881031	-2.78555469353892	0.00534362243751793	0.0222516673026291	2289	GTP pyrophosphokinase	NA	K00951	 Nucleotide metabolism	              Nucleotide metabolism	               00230 Purine metabolism	COG0317	TK
LFTS_01231	218.43836097603	-0.529576068331814	0.190266188328041	-2.78334302581793	0.00538018900742328	0.0223664713586192	567	putative kinase inhibitor protein	NA	K06910	NA	              Amino acid metabolism	               00350 Tyrosine metabolism	COG1881	R
LFTS_00146	19.9521268686787	-1.11713555693269	0.401539882035107	-2.78212851802107	0.0054003650127228	0.022396076015333	138	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00626	2365.2384312454	-0.36362982220348	0.130716029059864	-2.78183039080042	0.00540532808093315	0.022396076015333	831	sirohydrochlorin cobaltochelatase	NA	K03795	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00860 Porphyrin and chlorophyll metabolism	COG2138	H
LFTS_02250	182.720920250554	-0.804212907432249	0.289562008931655	-2.77734261617886	0.00548053746072371	0.0226699103616625	897	23S rRNA synthase	NA	K06178	NA	              Replication and repair	               03030 DNA replication	COG1187	J
LFTS_01930	456.774631505112	0.506210289656919	0.182632588492643	2.77174130769827	0.00557573283594192	0.0230253684886239	369	Cytochrome C oxidase%2C cbb3-type%2C subunit III	Cytochrome cbb3 oxidase	K00406	 Energy metabolism; Signal transduction	              Energy metabolism	               00190 Oxidative phosphorylation	COG2010	C
LFTS_01436	188.953425046548	0.570039734699038	0.20581663117386	2.76964855292722	0.00561168075566529	0.0231353869959932	183	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00089	907.627524466089	-0.425808411224431	0.153842610095653	-2.76781842793541	0.00564328863868534	0.0232271780724698	3603	diguanylate cyclase (GGDEF) domain-containing protein	Genes encoding proteins with EAL and GGDEF domains	K14051	 Cellular community - prokaryotes	              Cellular community - prokaryotes	               02024 Quorum sensing	COG2199;COG2200;COG2202	T
LFTS_00247	822.982912189035	0.479456771819377	0.17334711664235	2.76587682048726	0.00567699741726658	0.0233158282012641	324	YtxH-like protein	NA	K09908	NA	              Nucleotide metabolism	               00230 Purine metabolism	COG3105	S
LFTS_00901	1596.40107564828	-0.402312671969944	0.145475637329462	-2.76549860413271	0.00568358483104025	0.0233158282012641	1905	DNA mismatch repair protein MutL	NA	K03572	 Replication and repair	              Replication and repair	               03430 Mismatch repair	COG0323	L
LFTS_01049	309.294112496927	0.551592879697347	0.199705313766998	2.76203406555775	0.00574424847218573	0.0235258677131033	1416	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_02404	787.052001745466	0.545021112166407	0.197404638506883	2.76093366543362	0.00576363816358753	0.0235664547280898	495	hypothetical protein	NA	K03571	NA	              Overview	               01200 Carbon metabolism	COG2891	M
LFTS_00932	850.177080102885	0.429306074676969	0.156145380217106	2.74939978422709	0.00597045168280563	0.024371991598448	1575	preprotein translocase subunit SecD	NA	K12257	 Cellular community - prokaryotes; Folding, sorting and degradation; Membrane transport	              Folding, sorting and degradation	               03060 Protein export	COG0342;COG0341	U
LFTS_01791	112.083816259007	0.64788309243243	0.236455886805494	2.73997446705723	0.00614439574836214	0.0250409308695546	252	IstB-like ATP binding protein	NA	K02315	NA	              Signal transduction	               02020 Two-component system	COG1484	L
LFTS_00380	159.671160643573	-0.611418369500368	0.223387303562523	-2.73703276663278	0.00619961176291329	0.0252128373023053	1104	Site-specific recombinase XerD	NA	K14059	NA	              Replication and repair	               03030 DNA replication	COG0582	LX
LFTS_01341	1013.56571815978	0.399416731100494	0.145953130130569	2.7366095591316	0.00620759206496855	0.0252128373023053	1524	lysyl-tRNA synthetase%2C class II	NA	K04567	 Translation	              Translation	               00970 Aminoacyl-tRNA biosynthesis	COG1190	J
LFTS_00272	407.633461909799	-0.494028929583399	0.180580969509299	-2.73577515352724	0.00622335331109781	0.0252128373023053	507	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00991	233.386089630367	-0.543041630745716	0.198510985047506	-2.73557471197758	0.00622714485262085	0.0252128373023053	705	exodeoxyribonuclease X	NA	K10857	 Replication and repair	              Replication and repair	               03430 Mismatch repair	COG0847	L
LFTS_00986	1630.99051780436	-0.397876338992698	0.145494142050663	-2.7346553846419	0.00624456145581099	0.025242243543327	1896	DNA adenine methylase	NA	K06223	 Replication and repair	              Replication and repair	               03430 Mismatch repair	COG0338	L
LFTS_02139	627.603462353452	-0.384243086615111	0.140714038303608	-2.73066633043434	0.00632064292242554	0.0255083089369316	1434	Purine-cytosine permease	NA	K03457	NA	              Translation	               03010 Ribosome	COG1457;COG1953	FFH
LFTS_02022	91.4558136684623	-0.688237108546767	0.252836473576818	-2.72206418168407	0.00648755413881609	0.0261394806954567	1368	hypothetical protein	NA	K07505	NA	              Glycan biosynthesis and metabolism	               00550 Peptidoglycan biosynthesis	COG3598	L
LFTS_00338	1871.73758025271	-0.388095885555818	0.14280780637829	-2.71760973995898	0.00657553456918665	0.0264367267388536	840	proteasome beta subunit	NA	K03433	 Folding, sorting and degradation	              Folding, sorting and degradation	               03050 Proteasome	COG0638	O
LFTS_00451	209.281755026228	0.782595351688376	0.288009584283472	2.71725454427277	0.00658259607858021	0.0264367267388536	1449	Putative beta-barrel porin-2%2C OmpL-like. bbp2	NA	NA	NA	NA	NA	NA	NA
LFTS_02446	477.474840100786	0.39705644984698	0.146547435051444	2.70940565904547	0.00674038712224086	0.0270267780417593	528	Phosphate-starvation-inducible E	NA	K13256	NA	              Aging	               04213 Longevity regulating pathway - multiple species	COG3223	R
LFTS_01799	2965.12403304321	0.473102477783748	0.17465153973318	2.70883656970057	0.00675195899705951	0.0270295814278421	939	hypothetical protein	NA	K00477	 Transport and catabolism	              Transport and catabolism	               04146 Peroxisome	NA	
LFTS_00194	285.457170903003	-0.476859171086552	0.176175046919464	-2.70673503100891	0.00679484660427071	0.0271575380357186	846	HDIG domain-containing protein	NA	K07181	 Cellular community - prokaryotes	              Cellular community - prokaryotes	               05111 Biofilm formation - Vibrio cholerae	COG2200;COG3434	T
LFTS_00401	1609.60357488362	-0.377379124945434	0.13948170315658	-2.70558156665032	0.00681849009414329	0.027208292735217	726	hypothetical protein	NA	K02656	NA	              Cellular community - prokaryotes	               02024 Quorum sensing	COG3063	NW
LFTS_01415	196.193583845801	0.507864113160511	0.188114809347798	2.6997561484994	0.00693903160068028	0.027644923973223	654	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00093	968.544453196611	0.342756139917331	0.127012068074078	2.6986108100958	0.00696295527879911	0.0276958509169513	357	LSU ribosomal protein L20P	NA	K02887	 Translation	              Translation	               03010 Ribosome	COG0292	J
LFTS_00263	301.627937365385	-0.460420455472183	0.17065495515054	-2.69796124622359	0.00697655618176054	0.0277056208751705	861	pantoate--beta-alanine ligase	NA	K01918	 Metabolism of cofactors and vitamins; Metabolism of other amino acids	              Metabolism of other amino acids	               00410 beta-Alanine metabolism	COG0414	H
LFTS_00454	253.369487270781	0.810990827213591	0.301040595485595	2.69395835437217	0.00706089865322922	0.027995843782979	2013	K+-transporting ATPase ATPase B chain	Role of potassium in the internal positive membrane potential	K01547	 Signal transduction	              Signal transduction	               02020 Two-component system	COG2216	P
LFTS_02123	813.055047158447	0.416813265413856	0.155118103220244	2.68707041125976	0.00720817562055459	0.0285342748291381	468	Fur family transcriptional regulator%2C peroxide stress response regulator	Oxidative stress response	K09825	NA	              Cell growth and death	               04214 Apoptosis - fly	COG0735	P
LFTS_02217	80.925050370594	0.737217378159094	0.275089948000932	2.67991391003715	0.00736410968852578	0.0291052093571941	288	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00252	178.794164780313	-0.577512515837161	0.215879619978332	-2.67515996134849	0.00746936019558825	0.0294743324543371	273	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00763	697.387804052924	-0.506860523159332	0.189671916245567	-2.6723013780443	0.00753329566771849	0.0296795135181429	510	transcriptional regulator%2C BadM/Rrf2 family	NA	K13771	 Infectious diseases	              Infectious diseases	               05132 Salmonella infection	COG1959	K
LFTS_00193	369.429709728726	-0.465649831060195	0.174287555449959	-2.67173310141407	0.00754606413950186	0.0296827776120279	864	HDIG domain-containing protein	NA	K07181	 Cellular community - prokaryotes	              Cellular community - prokaryotes	               05111 Biofilm formation - Vibrio cholerae	COG2200;COG3434	T
LFTS_01426	54.5146832343541	0.779783592358105	0.292039283087004	2.67013253873039	0.0075821311554176	0.0297775324681961	177	Transposase DDE domain group 1	NA	NA	NA	NA	NA	NA	NA
LFTS_02118	658.462143387806	0.398128115983649	0.14933217356216	2.66605719642811	0.00767466345730207	0.0300933964587586	651	2-hydroxy-3-keto-5-methylthiopentenyl-1- phosphate phosphatase	NA	K08966	 Amino acid metabolism	              Amino acid metabolism	               00270 Cysteine and methionine metabolism	COG4359	E
LFTS_00905	902.355988898131	0.37465151987371	0.140698554532334	2.66279579857099	0.00774944254301952	0.0303387624597583	765	Tfp pilus assembly protein PilF	NA	K02656	NA	              Carbohydrate metabolism	               00030 Pentose phosphate pathway	COG3063	NW
LFTS_02067	404.569232329405	-0.456811023443137	0.171720435816748	-2.66020186397981	0.00780938310799943	0.0305253559850418	3306	DNA helicase/exodeoxyribonuclease V%2C beta subunit	NA	K03582	 Replication and repair	              Replication and repair	               03440 Homologous recombination	COG1074	L
LFTS_01193	48.9092546983758	-0.843031224748189	0.317570232776858	-2.6546292370562	0.00793956200414036	0.0309854806001459	489	LTXXQ motif family protein	NA	K06006	NA	              Membrane transport	               02010 ABC transporters	COG3678	O
LFTS_00493	2067.00215938928	-0.403842856373697	0.152807480299927	-2.6428212518199	0.00822184276505003	0.0320368356017467	2718	PAS domain S-box-containing protein/diguanylate cyclase (GGDEF) domain-containing protein	Genes encoding proteins with EAL and GGDEF domains	K14051	 Cellular community - prokaryotes	              Cellular community - prokaryotes	               02024 Quorum sensing	COG2199;COG2200;COG2202	T
LFTS_02426	734.580653234827	0.385252988648212	0.146069035032987	2.63747199097475	0.00835265230149699	0.0324956081713952	1005	UDPglucose--hexose-1-phosphate uridylyltransferase	Extracellular polysaccharide production and export	K00965	 Endocrine system; Carbohydrate metabolism	              Carbohydrate metabolism	               00052 Galactose metabolism	COG1085	G
LFTS_00871	219.078909344419	-0.626327665058908	0.237521411876709	-2.63693138277579	0.00836597523869771	0.0324965850678164	183	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00312	125.640454008834	-0.792578018600696	0.300639834182756	-2.63630407046757	0.00838145876659648	0.0325059383677985	1308	ammonium transporter (TC 1.A.11)	Ammonia & glutamate conversion to glutamine	K03320	NA	              Signal transduction	               02020 Two-component system	COG0004	P
LFTS_00768	695.847220981523	0.367593373536657	0.139559353378445	2.63395727078105	0.00843961081061825	0.0326324872278543	402	nitric oxide dioxygenase	NA	K05916	 Infectious diseases	              Infectious diseases	               05132 Salmonella infection	COG1017;COG1018	C
LFTS_01190	247.73441776997	-0.62583964654386	0.237606979944051	-2.633927869843	0.00844034162812161	0.0326324872278543	828	molybdate transport system substrate-binding protein	NA	K02020	 Membrane transport	              Membrane transport	               02010 ABC transporters	COG0725	P
LFTS_02231	353.842102244874	0.428545574017395	0.162741010147122	2.63329798450912	0.00845601225426217	0.0326423081740617	873	Glyoxylase%2C beta-lactamase superfamily II	NA	K05337	NA	              Metabolism of cofactors and vitamins	               00770 Pantothenate and CoA biosynthesis	COG1141	C
LFTS_00313	391.886338609146	-0.468997043433046	0.17826550574907	-2.63089060030052	0.00851614448260805	0.0328234654011839	2532	Cu+-exporting ATPase	Copper resistance	K01533	NA	              Signal transduction	               02020 Two-component system	COG2217	P
LFTS_02167	2523.58156635732	0.442709172081357	0.168602430667859	2.62575794623909	0.00864562741225268	0.0332709438805885	1134	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase	NA	K03526	 Metabolism of terpenoids and polyketides	              Metabolism of terpenoids and polyketides	               00900 Terpenoid backbone biosynthesis	COG0821	I
LFTS_02237	1060.81696292101	0.378692622256211	0.144268512435643	2.62491527681858	0.00866705303208476	0.0333018451897414	672	phosphoglycerate mutase	NA	K01834	 Overview; Amino acid metabolism; Endocrine system; Cancers; Carbohydrate metabolism; Energy metabolism	              Overview	               01200 Carbon metabolism	COG0588	G
LFTS_00873	1733.85441199527	0.430539110703281	0.164055364798164	2.62435252411873	0.00868138793671947	0.0333054481646367	1218	Transposase (or an inactivated derivative)	NA	K07493	NA	              Metabolism of cofactors and vitamins	               00770 Pantothenate and CoA biosynthesis	COG3328	X
LFTS_00810	2994.06307200446	-0.47464838172499	0.181081502081928	-2.62118646171955	0.00876243217406616	0.0335645707006602	120	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00592	722.774104937145	0.399283153522778	0.152373818916529	2.62041836558225	0.00878219536275141	0.0335885194950769	924	16S rRNA (cytosine1402-N4)-methyltransferase	NA	K03438	NA	              Overview	               01200 Carbon metabolism	COG0275	J
LFTS_01699	3093.64026188476	0.373570886159092	0.142607895468964	2.61956664412309	0.00880415679882283	0.0336207892501898	1281	ATP-dependent Clp protease ATP-binding subunit ClpX	NA	K03544	 Cell growth and death	              Cell growth and death	               04112 Cell cycle - Caulobacter	COG1219	O
LFTS_02084	945.779797316413	-0.657531105178361	0.251245022804886	-2.61709106846265	0.00886826776194196	0.0338136712518217	1104	N-ethylmaleimide reductase	NA	K10680	 Xenobiotics biodegradation and metabolism	              Xenobiotics biodegradation and metabolism	               00633 Nitrotoluene degradation	COG1902	C
LFTS_00455	144.358058753767	-0.806903376439677	0.308776226462362	-2.61323025313295	0.0089690853977191	0.0341342857059759	609	hypothetical protein	NA	K14953	 Infectious diseases	              Infectious diseases	               05152 Tuberculosis	NA	
LFTS_02296	1100.53029230307	-0.373090401703584	0.142792145065613	-2.61282160536316	0.00897981611090436	0.0341342857059759	648	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01536	780.337289816938	0.401443041695431	0.154030298852889	2.60626022727412	0.00915368875597155	0.034699096828456	1365	3-phosphoshikimate 1-carboxyvinyltransferase	NA	K00800	 Overview; Amino acid metabolism	              Overview	               01230 Biosynthesis of amino acids	COG0128	E
LFTS_02224	827.670300357764	-0.461545874629463	0.17712355960443	-2.60578477341035	0.00916640400413773	0.034699096828456	1170	putative ATPase	NA	K06926	NA	              Lipid metabolism	               00564 Glycerophospholipid metabolism	COG1106	R
LFTS_00747	734.368195366379	0.508494517054891	0.195151478167284	2.60564009983573	0.00917027619320016	0.034699096828456	717	FMN phosphatase YigB%2C HAD superfamily	NA	K07025	NA	              Overview	               01200 Carbon metabolism	COG1011	H
LFTS_00301	467.061900592765	0.450896572959756	0.173289391082396	2.60198601970598	0.00926856304907807	0.0350177017325351	351	putative protein involved in oxidation of intracellular sulfur	NA	K06039	NA	              Folding, sorting and degradation	               04122 Sulfur relay system	COG1553	P
LFTS_01026	436.469180753668	-0.441417733524808	0.169951268796347	-2.59731943545393	0.00939545036034154	0.0354432315566147	249	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01949	4434.20495079269	0.332395394841487	0.128031666182895	2.59619674375444	0.00942620734294791	0.0355053809917705	915	acetyl-CoA carboxylase carboxyltransferase subunit alpha	NA	K01963	 Carbohydrate metabolism; Overview; Energy metabolism; Lipid metabolism	              Overview	               01200 Carbon metabolism	COG0777	I
LFTS_01568	3100.20699863442	0.45774608675681	0.176364389855657	2.59545641345991	0.00944653835476146	0.0355281306353056	540	hypothetical protein	NA	K11550	NA	              Metabolism of cofactors and vitamins	               00860 Porphyrin and chlorophyll metabolism	NA	
LFTS_00250	180.973306610045	0.533133253642312	0.205462518796043	2.59479566767863	0.00946471683222148	0.0355427281645054	768	NitT/TauT family transport system ATP-binding protein	NA	K02049	NA	              Signal transduction	               02020 Two-component system	COG1116	P
LFTS_01532	976.037228577919	0.368002523354452	0.141868646792428	2.5939665435231	0.00948757188132592	0.0355748170391798	759	DNA-binding regulatory protein%2C YebC/PmpR family	NA	K07741	NA	              Overview	               01230 Biosynthesis of amino acids	COG3561	X
LFTS_02395	11661.6755326074	0.348701521851538	0.134460791719184	2.59333235654143	0.00950508663938554	0.0355868153396272	1503	hypothetical protein	NA	K04034	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00860 Porphyrin and chlorophyll metabolism	COG1032	R
LFTS_02381	4423.81042545978	0.341470631969615	0.131830961588382	2.59021574185126	0.00959157996554515	0.0358067418862502	852	cytochrome c-type biogenesis protein CcsB	Cytochrome c	K02497	NA	              Nucleotide metabolism	               00240 Pyrimidine metabolism	COG0755	O
LFTS_00341	1262.62480328623	-0.431750064467249	0.166704973407087	-2.5899051218642	0.0096002387331926	0.0358067418862502	693	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00797	1801.07150410829	0.345017681980401	0.133228878829483	2.5896613783111	0.00960703814888531	0.0358067418862502	978	Protein-disulfide isomerase	NA	K03981	NA	              Carbohydrate metabolism	               00650 Butanoate metabolism	COG1651	O
LFTS_00809	6621.49743945853	0.332846284724858	0.128943593529495	2.58133246960208	0.00984197473377586	0.0366274688445611	2142	polyribonucleotide nucleotidyltransferase	NA	K00962	 Nucleotide metabolism; Folding, sorting and degradation	              Nucleotide metabolism	               00230 Purine metabolism	COG1185	J
LFTS_02106	1095.957739918	-0.394390775622877	0.153104917730016	-2.57595106329859	0.0099964793227536	0.0371468573936703	1818	glucosamine--fructose-6-phosphate aminotransferase (isomerizing)	NA	K00820	 Amino acid metabolism; Carbohydrate metabolism; Endocrine and metabolic diseases	              Carbohydrate metabolism	               00520 Amino sugar and nucleotide sugar metabolism	COG0449	M
LFTS_00460	407.817864088691	-0.423283576117111	0.164454878552313	-2.57385843365214	0.01005714142761	0.0373164978940873	579	Outer membrane protein beta-barrel domain protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00488	721.635528969681	0.377762628973622	0.146901263536992	2.57154104653766	0.0101247012534782	0.0375111882505912	1074	dTDP-glucose 4%2C6-dehydratase	Extracellular polysaccharide production and export	K01710	 Biosynthesis of other secondary metabolites; Metabolism of terpenoids and polyketides	              Metabolism of terpenoids and polyketides	               00523 Polyketide sugar unit biosynthesis	COG1088	M
LFTS_00175	1486.88602942182	-0.319791898656433	0.124414509378465	-2.57037463117454	0.0101588589315114	0.0375817311067521	1485	Thiol-disulfide isomerase or thioredoxin	NA	K12035	 Cancers	              Cancers	               05206 MicroRNAs in cancer	NA	
LFTS_01543	1257.51486174744	-0.363905649766734	0.141890645291575	-2.5646909210888	0.0103267748516796	0.0381461549498891	870	5%2C10-methylenetetrahydrofolate reductase	NA	K00297	 Metabolism of cofactors and vitamins; Overview; Energy metabolism; Drug resistance	              Overview	               01200 Carbon metabolism	COG0685	E
LFTS_01529	585.557360916434	0.445573362244991	0.173907633348621	2.56212653616981	0.0104033407625597	0.0383719660767411	1128	glycine oxidase	NA	K03153	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00730 Thiamine metabolism	COG0665	E
LFTS_02158	3759.28992529946	0.386739069653284	0.15103812552325	2.56053938906804	0.0104509815544263	0.0384338770395383	1209	3-oxoacyl-[acyl-carrier-protein] synthase II	NA	K09458	 Lipid metabolism; Overview; Metabolism of cofactors and vitamins	              Overview	               01212 Fatty acid metabolism	COG0304	IQ
LFTS_01901	1692.97095881811	0.389737848101914	0.152209404377372	2.56053723944441	0.0104510462102687	0.0384338770395383	1470	IMP dehydrogenase	NA	K00088	 Xenobiotics biodegradation and metabolism; Nucleotide metabolism	              Nucleotide metabolism	               00230 Purine metabolism	COG0516;COG0517	FT
LFTS_02425	1412.92205475915	0.486062201152467	0.190362347426456	2.55335263366749	0.0106691416542516	0.039177970683116	1383	Fructose/tagatose bisphosphate aldolase	NA	K01624	 Carbohydrate metabolism; Overview; Energy metabolism	              Overview	               01200 Carbon metabolism	COG0191	G
LFTS_01678	2177.60488993916	0.572315346118215	0.224329310536956	2.5512285699462	0.0107343901119048	0.0393435735058758	1140	sulfide:quinone oxidoreductase	NA	K00386	NA	NA	NA	NA	
LFTS_01716	3561.57111016605	0.362980697811597	0.142297640673424	2.5508553486466	0.0107458915569146	0.0393435735058758	1029	hopanoid biosynthesis associated radical SAM protein HpnH	NA	K03639	 Metabolism of cofactors and vitamins; Folding, sorting and degradation	              Metabolism of cofactors and vitamins	               00790 Folate biosynthesis	COG2896	H
LFTS_00083	663.23796438707	-0.409508981602769	0.160751454181579	-2.54746673171742	0.0108508198721753	0.0396693208856293	876	lactoylglutathione lyase	NA	K08234	NA	              Glycan biosynthesis and metabolism	               00540 Lipopolysaccharide biosynthesis	COG0346	Q
LFTS_00782	1737.28513135019	0.375691919325475	0.147755756306619	2.54265504584368	0.0110013780032516	0.0401290802828175	2448	5-methyltetrahydrofolate--homocysteine methyltransferase	NA	K00548	 Amino acid metabolism; Overview; Metabolism of cofactors and vitamins; Metabolism of other amino acids	              Overview	               01230 Biosynthesis of amino acids	COG0646;COG1410	E
LFTS_00126	6367.06860739421	-0.313486616146334	0.123302577955318	-2.54241737151622	0.0110088627324544	0.0401290802828175	540	peptidoglycan-associated lipoprotein	NA	K03640	NA	              Translation	               03010 Ribosome	COG2885	M
LFTS_01825	165.373697083404	-0.60545115162752	0.238318392061422	-2.54051374881498	0.0110689741566227	0.0402891211615871	1020	translation factor SUA5	NA	K07566	NA	              Overview	               01210 2-Oxocarboxylic acid metabolism	COG0009	J
LFTS_00587	1710.85883873217	0.386686693599912	0.152463368156972	2.53625968174723	0.01120436151014	0.0407190116571855	918	succinyl-CoA synthetase alpha subunit	Reductive TCA cycle carbon dioxide fixation	K01902	 Carbohydrate metabolism; Overview; Energy metabolism	              Overview	               01200 Carbon metabolism	COG0074	C
LFTS_01829	1254.1440093126	-0.540124906195394	0.21300180205845	-2.53577622806768	0.0112198402997474	0.0407190116571855	2481	hypothetical protein	NA	K09822	NA	              Energy metabolism	               00190 Oxidative phosphorylation	COG3002	S
LFTS_00659	193.996293605283	0.491878635280644	0.194228001093193	2.53248055127044	0.0113258652642462	0.0410438790771373	723	phospholipid/cholesterol/gamma-HCH transport system ATP-binding protein	NA	K02065	 Membrane transport	              Membrane transport	               02010 ABC transporters	COG1127	M
LFTS_01530	460.958097717443	0.459109129444362	0.18134986932686	2.53162095538584	0.0113536651158426	0.0410847328646064	1260	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_02080	669.724147837218	0.394291400168489	0.156211220607638	2.5240914105578	0.0115997761543711	0.0419143074415211	1296	adenine-specific DNA-methyltransferase	NA	K07316	NA	              Carbohydrate metabolism	               00520 Amino sugar and nucleotide sugar metabolism	COG2189	L
LFTS_01936	375.809772986263	0.463930002596729	0.183871723990457	2.52311770689009	0.0116319458824885	0.0419303438296226	495	putative nucleotide-binding protein	NA	K09767	NA	              Energy metabolism	               00190 Oxidative phosphorylation	COG1666	S
LFTS_01440	353.425803790692	0.491590241057799	0.194848453890702	2.52293631918451	0.0116379474024294	0.0419303438296226	1068	tryptophanyl-tRNA synthetase	NA	K01867	 Translation	              Translation	               00970 Aminoacyl-tRNA biosynthesis	COG0180	J
LFTS_00590	1247.73816304733	-0.385204871470729	0.152849239066468	-2.52016217956583	0.0117300774360265	0.0422011179536353	243	putative regulatory protein%2C FmdB family	NA	K03059	 Nucleotide metabolism; Transcription	              Nucleotide metabolism	               00230 Purine metabolism	COG1996	K
LFTS_02109	776.465350239298	-0.42109814561104	0.16753901575044	-2.51343332611129	0.0119562375666938	0.042952610680348	858	hypothetical protein	NA	K07275	NA	              Membrane transport	               02010 ABC transporters	COG3047	M
LFTS_00287	360.469925841884	0.463466724086141	0.184579544858029	2.51093220780569	0.0120412818531091	0.043195709504804	927	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00101	967.348074149601	0.362512626249478	0.14449984776835	2.50874054089405	0.012116244359602	0.0434019934841076	462	Fur family transcriptional regulator%2C ferric uptake regulator	NA	K03711	NA	              Lipid metabolism	               00600 Sphingolipid metabolism	COG0735	P
LFTS_01348	812.182450447373	-0.373424189494041	0.149085950227654	-2.50475775164476	0.012253528688377	0.0437682951230415	363	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00280	58.1282774043814	0.683067016395919	0.272761858416306	2.50426148421888	0.0122707309253994	0.0437682951230415	120	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00836	529.534379036252	0.427831312600301	0.170842468776999	2.50424449882394	0.0122713200727112	0.0437682951230415	786	S-adenosyl-l-methionine hydroxide adenosyltransferase	NA	K09134	NA	              Immune system	               04621 NOD-like receptor signaling pathway	COG1912	H
LFTS_00786	1232.13680274995	-0.390197299417639	0.156094524845564	-2.49975007005332	0.0124280950837089	0.0442639604270777	1899	Excinuclease ABC subunit C	NA	K03703	 Replication and repair	              Replication and repair	               03420 Nucleotide excision repair	COG0322	L
LFTS_00498	999.41477360326	0.531499429712623	0.212801321511575	2.4976321854454	0.0125025842722373	0.0444655572257251	1671	maltose alpha-D-glucosyltransferase/ alpha-amylase	NA	K05343	 Carbohydrate metabolism	              Carbohydrate metabolism	               00500 Starch and sucrose metabolism	COG0366	G
LFTS_00588	5638.56928886624	0.357913890056861	0.143339599904794	2.49696448360808	0.0125261501776458	0.0444857276308962	462	peroxiredoxin (alkyl hydroperoxide reductase subunit C)	Oxidative stress response	K03564	NA	              Membrane transport	               03070 Bacterial secretion system	COG1225	O
LFTS_00516	1581.65397054364	-0.334362116978002	0.134099713984076	-2.49338426641018	0.0126531826326355	0.0448727703633837	1776	Signal transduction histidine kinase	Quorum sensing	K10715	 Cellular community - prokaryotes; Signal transduction	              Signal transduction	               02020 Two-component system	COG0642;COG0784	T
LFTS_01665	7759.12065633662	0.444890975916324	0.178884745845633	2.48702578754389	0.0128816061245291	0.0456177675578053	5157	DNA-directed RNA polymerase subunit beta	NA	K03043	 Nucleotide metabolism; Transcription	              Nucleotide metabolism	               00230 Purine metabolism	COG0085	K
LFTS_02215	1399.53696718829	0.387258672040403	0.155922666872816	2.48365859696515	0.0130040413607432	0.0459858418532113	1218	Transposase (or an inactivated derivative)	NA	K07493	NA	              Overview	               01200 Carbon metabolism	COG3328	X
LFTS_00610	532.198227696901	-0.381469294633596	0.153735708997971	-2.48133174211745	0.0130892490315364	0.0462214106426129	816	pyrroline-5-carboxylate reductase	NA	K00286	 Amino acid metabolism; Overview	              Overview	               01230 Biosynthesis of amino acids	COG0345	E
LFTS_01005	177.445046802635	-0.486616828469855	0.196186845685545	-2.4803743939582	0.0131244495214205	0.0462799737734063	135	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00541	148.072248690888	-0.515498254181435	0.207941257390803	-2.47905711761958	0.0131730209470955	0.0463854533632854	1011	Glycosyltransferase involved in cell wall bisynthesis	Extracellular polysaccharide production and export	K00786	NA	              Cell motility	               02030 Bacterial chemotaxis	NA	
LFTS_01822	206.139657381944	-0.719178998919625	0.290233099698843	-2.47793583731791	0.0132144906437855	0.0464656629992231	2472	hypothetical protein	NA	K09822	NA	              Energy metabolism	               00190 Oxidative phosphorylation	COG3002	S
LFTS_00780	1217.72215817262	0.399388365673225	0.161264925694833	2.47659783398282	0.0132641266884276	0.0465743205472188	657	peptidyl-prolyl cis-trans isomerase A (cyclophilin A)	NA	K03767	 Drug resistance	              Drug resistance	               01503 Cationic antimicrobial peptide (CAMP) resistance	COG0652	O
LFTS_01482	454.498870512946	0.47171621306374	0.190747653408202	2.47298566789842	0.0133989516320232	0.0469813734234269	138	hypothetical protein	NA	K08714	NA	              Metabolism of terpenoids and polyketides	               00523 Polyketide sugar unit biosynthesis	NA	
LFTS_01110	571.849813820834	-0.433973008528023	0.175640090529025	-2.47080838560777	0.013480802992373	0.0472017975197736	1347	putative transposase	NA	K07496	NA	              Signal transduction	               02020 Two-component system	COG0675	X
LFTS_01813	246.968828397309	-0.482855042170564	0.195663705369702	-2.46778032368456	0.0135953724612865	0.0475359999138652	795	ABC-2 type transport system permease protein	Lipopolysaccharide synthesis	K09690	 Membrane transport	              Membrane transport	               02010 ABC transporters	COG1682	GM
LFTS_00751	1312.90578181022	0.469258003296351	0.190296570993926	2.46592989482363	0.0136658077935344	0.0477151659757395	603	outer membrane lipoprotein	NA	K07285	NA	              Energy metabolism	               00190 Oxidative phosphorylation	COG3065	M
LFTS_01664	9448.13218505133	0.438573798111095	0.17804996162961	2.46320636127652	0.0137700636046341	0.0480117505205055	4758	DNA-directed RNA polymerase subunit beta'	NA	K03046	 Nucleotide metabolism; Transcription	              Nucleotide metabolism	               00230 Purine metabolism	COG0086	K
LFTS_00799	1162.92644734435	0.363871607651091	0.147828151244682	2.46145003226631	0.0138376671443195	0.0481798886845632	981	two-component system%2C chemotaxis family%2C response regulator CheV	Chemotaxis	K03415	 Signal transduction; Cell motility	              Signal transduction	               02020 Two-component system	COG0784;COG0835	TNT
LFTS_00711	440.803596291056	-0.384337070057537	0.156287343883087	-2.45916950476198	0.0139258850293501	0.0484192310251248	648	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00441	122.216006013973	0.58081540467615	0.236338963735828	2.4575524724961	0.0139887373359966	0.0485698338230274	132	cyd operon protein YbgT	Cytochrome bd	K00426	 Energy metabolism; Signal transduction	              Energy metabolism	               00190 Oxidative phosphorylation	COG1294	C
LFTS_01313	713.398977826937	0.34240498529026	0.139374516655801	2.45672590302762	0.0140209618111539	0.0486138229602908	186	hypothetical protein	NA	K09791	NA	              Glycan biosynthesis and metabolism	               00540 Lipopolysaccharide biosynthesis	COG2835	S
LFTS_01329	518.4567435022	-0.401451721688544	0.163811995824852	-2.45068573682343	0.0142584379052417	0.0493683518557531	1212	heptosyltransferase-2	Lipopolysaccharide synthesis	K02843	 Glycan biosynthesis and metabolism	              Glycan biosynthesis and metabolism	               00540 Lipopolysaccharide biosynthesis	COG0859	M
LFTS_00775	289.151009458555	-0.429506076066223	0.175340827946556	-2.44954972037166	0.0143034960407313	0.0494554814426399	741	DNA replication and repair protein RecO	NA	K03584	 Replication and repair	              Replication and repair	               03440 Homologous recombination	COG1381	L
LFTS_00748	665.012841642973	0.402197231109456	0.164422347563879	2.44612266561392	0.0144401861758158	0.0498051779149008	378	hypothetical protein	NA	K06940	NA	              Overview	               01200 Carbon metabolism	COG0727	R
LFTS_01561	593.73066586579	0.399300845770488	0.163245801560976	2.44600989399008	0.0144447036511036	0.0498051779149008	552	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00930	601.697452329115	0.346511480334113	0.141935507869588	2.4413304713891	0.0146332570420347	0.0503854252167565	1137	tRNA-guanine transglycosylase	NA	K00773	NA	              Folding, sorting and degradation	               03060 Protein export	COG0343	J
LFTS_00877	1921.16891847868	0.293753320967412	0.120364107201462	2.44053919226714	0.0146653545414697	0.0504261015077366	588	LPS export ABC transporter protein LptC	NA	K11719	NA	              Overview	               01200 Carbon metabolism	COG3117	M
LFTS_00189	1047.92559696147	-0.339703038423441	0.139283836746323	-2.43892648536197	0.014730964689223	0.0505183035605159	1362	glycine dehydrogenase subunit 1	NA	K00282	 Carbohydrate metabolism; Overview; Amino acid metabolism	              Overview	               01200 Carbon metabolism	COG0403	E
LFTS_02535	1380.21214293547	0.314894358575955	0.129125965087866	2.43866025211645	0.0147418207649892	0.0505183035605159	1050	aspartate-semialdehyde dehydrogenase	NA	K00133	 Amino acid metabolism; Overview; Biosynthesis of other secondary metabolites	              Overview	               01210 2-Oxocarboxylic acid metabolism	COG0136	E
LFTS_01219	1966.7758131601	-0.581342640805053	0.238413176450263	-2.43838301834098	0.0147531328982038	0.0505183035605159	2487	hypothetical protein	NA	K09822	NA	              Metabolism of cofactors and vitamins	               00860 Porphyrin and chlorophyll metabolism	COG3002	S
LFTS_00846	1287.34267891024	0.338728814253874	0.13935413256933	2.4307051969582	0.0150694702948075	0.0515305407880213	687	RNase HII	NA	K03470	 Replication and repair	              Replication and repair	               03030 DNA replication	COG0164	L
LFTS_00233	398.983338565837	-0.382197779848943	0.157277764201625	-2.43008146630937	0.0150954293754376	0.0515484030595301	816	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01823	73.7018689315421	-0.751848893409664	0.310653512823939	-2.42021693743335	0.0155112503314094	0.0528957041479888	867	hypothetical protein	NA	K02380	NA	              Energy metabolism	               00190 Oxidative phosphorylation	COG3058	CO
LFTS_01824	132.077801070781	-0.595630930987347	0.24645320169266	-2.41681149563693	0.0156571231945932	0.0533200113174775	1677	dihydroxyacid dehydratase	NA	K01687	 Metabolism of cofactors and vitamins; Amino acid metabolism; Overview	              Overview	               01210 2-Oxocarboxylic acid metabolism	COG0129	EG
LFTS_01883	581.176370518084	-0.438965588121076	0.181760184657618	-2.41508110782323	0.0157317061362176	0.0534446327760546	1308	histidyl-tRNA synthetase	NA	K01892	 Translation	              Translation	               00970 Aminoacyl-tRNA biosynthesis	COG0124	J
LFTS_00935	3992.45721609845	-0.285440682791193	0.118196603984674	-2.41496517808757	0.0157367140756524	0.0534446327760546	1650	single-stranded-DNA-specific exonuclease	NA	K07462	 Replication and repair	              Replication and repair	               03410 Base excision repair	COG0608	L
LFTS_00844	1974.19770442171	-0.413819401988201	0.171638195412935	-2.41099832699019	0.015908921417164	0.0539557689537104	726	tRNA (guanine37-N1)-methyltransferase	NA	K00554	NA	              Overview	               01220 Degradation of aromatic compounds	COG0336	J
LFTS_01339	201.909333279978	0.492764446077707	0.204536429628514	2.40917692253005	0.0159885450780824	0.0541519387794452	744	lipoprotein-releasing system ATP-binding protein	NA	K09810	 Membrane transport	              Membrane transport	               02010 ABC transporters	COG1136	M
LFTS_01192	72.0792039790653	-0.659095271937502	0.273751302035002	-2.40764250996414	0.0160558944334334	0.0543060592673678	795	thiamine transport system ATP-binding protein	NA	K02017	 Membrane transport	              Membrane transport	               02010 ABC transporters	COG1118	P
LFTS_02476	2207.84678129161	0.316975517113515	0.131682042772011	2.40712788502464	0.0160785384425379	0.0543087589241156	2931	Isoleucyl-tRNA synthetase	NA	K01870	 Translation	              Translation	               00970 Aminoacyl-tRNA biosynthesis	COG0060	J
LFTS_01133	27.555941171114	0.918700069025626	0.381896164465066	2.40562790231863	0.0161446994097957	0.0544499909603199	843	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01310	545.231215313722	0.444543329332864	0.184826868362647	2.40518780235258	0.016164156608494	0.0544499909603199	1035	Glycosyltransferase involved in cell wall bisynthesis	Lipopolysaccharide synthesis	K07011	NA	              Glycan biosynthesis and metabolism	               00540 Lipopolysaccharide biosynthesis	COG1216	G
LFTS_02150	1650.88526201544	0.518384775958624	0.215787315652817	2.40229493744971	0.0162925663982647	0.0548082815508605	1407	glucose-6-phosphate 1-dehydrogenase	NA	K00036	 Carbohydrate metabolism; Metabolism of other amino acids; Overview; Cancers	              Overview	               01200 Carbon metabolism	COG0364	G
LFTS_02124	6524.3852645858	-0.587246284886047	0.244710685341659	-2.399757428108	0.0164059395793938	0.0551150889113149	90	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00977	284.452559806685	-0.410094626005368	0.170943626152098	-2.39900507106644	0.0164396870196338	0.055153929731187	2514	type IV secretion system protein VirB4	NA	K03199	 Membrane transport	              Membrane transport	               03070 Bacterial secretion system	COG3451	U
LFTS_01478	113.503246652679	0.544121484609092	0.226928607204521	2.39776505620862	0.0164954417432741	0.0552663991560369	192	hypothetical protein	NA	K07301	NA	              Overview	               01212 Fatty acid metabolism	COG0530	P
LFTS_02100	2157.29036022168	-0.343194745229797	0.143224694320563	-2.3961981336938	0.0165661326921106	0.0554285408783137	1473	aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B	NA	K02434	 Translation	              Translation	               00970 Aminoacyl-tRNA biosynthesis	COG0064	J
LFTS_00121	728.937846908594	0.333185720420195	0.139140382588344	2.39460115188808	0.0166384533766783	0.0555533064675476	894	UDP-glucose pyrophosphorylase	Extracellular polysaccharide production and export	K00973	 Biosynthesis of other secondary metabolites; Metabolism of terpenoids and polyketides	              Metabolism of terpenoids and polyketides	               00523 Polyketide sugar unit biosynthesis	COG1209	M
LFTS_01899	705.742264394815	-0.386632885888022	0.161474598974809	-2.39438827123726	0.0166481147700414	0.0555533064675476	903	hypothetical protein	NA	K06923	NA	              Overview	               01200 Carbon metabolism	COG2607	R
LFTS_00279	187.950650515065	0.450108527885107	0.188808554298617	2.38394139268299	0.0171283299377002	0.057079126307135	330	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00393	225.201483159405	-0.492998402140459	0.206891343882936	-2.38288559051272	0.0171775319752746	0.0571664584879955	1293	MoxR-like ATPase	NA	K04748	NA	              Carbohydrate metabolism	               00520 Amino sugar and nucleotide sugar metabolism	COG0714	R
LFTS_02427	1460.97620516053	0.386583108038302	0.162415423896497	2.38021179740084	0.0173026898993551	0.0575059987831508	2094	hypothetical protein	NA	K07405	 Carbohydrate metabolism	              Carbohydrate metabolism	               00500 Starch and sucrose metabolism	COG1449	G
LFTS_01682	634.747157307983	0.380082662575677	0.159776704770582	2.37883653390791	0.0173673757192358	0.0576439199439523	171	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01661	7253.72749767338	0.410678317191582	0.172854032171696	2.37586773089363	0.0175077374525975	0.0580323137428765	2079	translation elongation factor 2 (EF-2/EF-G)	NA	K02355	NA	              Membrane transport	               03070 Bacterial secretion system	COG0480	J
LFTS_00016	421.760067829734	-0.453302730992318	0.191063319499578	-2.37252619801427	0.0176669102070183	0.0584819424429393	408	Plasmid maintenance system killer protein	NA	K07334	NA	              Replication and repair	               03410 Base excision repair	COG3549	V
LFTS_00658	331.551791102757	0.402908462414704	0.169918739638929	2.37118320952044	0.0177312394460397	0.0586168367857111	777	phospholipid/cholesterol/gamma-HCH transport system permease protein	NA	K02066	 Membrane transport	              Membrane transport	               02010 ABC transporters	COG0767	M
LFTS_01008	625.449095336065	0.394900291430975	0.166875087536017	2.36644245262639	0.0179599661676376	0.0592941246915632	732	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00021	384.817208822233	-0.450415631105451	0.190620406180798	-2.36289304030884	0.0181329021715486	0.059785669493992	672	ChrR Cupin-like domain-containing protein	NA	K07167	NA	              Cell growth and death	               04112 Cell cycle - Caulobacter	COG3806	T
LFTS_02092	18.9228723412213	-0.924634400404048	0.39148454237907	-2.36186694571643	0.0181831669423196	0.0598719907531213	513	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_02356	1641.0087418097	0.293553523716791	0.124440892116748	2.35897958238184	0.0183252639911108	0.0602600612194463	1227	argininosuccinate synthase	NA	K01940	 Amino acid metabolism; Overview; Cardiovascular diseases	              Overview	               01230 Biosynthesis of amino acids	COG0137	E
LFTS_02214	202.915409276443	0.49142258481453	0.208468770803304	2.35729592936584	0.0184085702326052	0.0604540364574063	417	Nucleotidyl transferase AbiEii toxin%2C Type IV TA system	NA	NA	NA	NA	NA	NA	NA
LFTS_02360	2733.37413378416	0.289368447352271	0.12281300552994	2.3561710431533	0.0184644135401903	0.0605574301595161	1380	putative arabinose efflux permease%2C MFS family	NA	K08153	NA	              Metabolism of cofactors and vitamins	               00130 Ubiquinone and other terpenoid-quinone biosynthesis	COG0477	GEPR
LFTS_00444	912.39476957002	0.63984558934125	0.271765551975603	2.35440284719636	0.0185524927054344	0.0607661355279446	453	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01410	191.32328201683	0.455506447858977	0.193638561520797	2.35235401606749	0.0186550107828833	0.0610215221134842	1164	hypothetical protein	NA	K02067	 Membrane transport	              Membrane transport	               02010 ABC transporters	COG1463	M
LFTS_00701	732.926042718695	0.359575945840745	0.153172903831793	2.34751667459157	0.0188990272130591	0.0617384778602693	669	repressor LexA	NA	K01356	NA	              Energy metabolism	               00190 Oxidative phosphorylation	COG1974	KT
LFTS_02317	749.276479354126	0.372562882028686	0.158938032713512	2.34407634011826	0.0190742668195225	0.0622291697025368	1653	Nif-specific regulatory protein	Nitrate/nitrite regulation	K02584	 Signal transduction	              Signal transduction	               02020 Two-component system	COG3604	KT
LFTS_00152	763.207314682927	0.333954503506283	0.14291670983861	2.33670719038665	0.0194544144127584	0.0633862047576899	942	Mechanosensitive ion channel	NA	K05802	NA	              Replication and repair	               03440 Homologous recombination	COG3264	M
LFTS_01526	625.945193264383	0.378639312958209	0.162160602080081	2.33496489345312	0.0195452547838221	0.0635433284403417	927	UDP-glucuronate decarboxylase	Extracellular polysaccharide production and export	K08678	 Carbohydrate metabolism	              Carbohydrate metabolism	               00520 Amino sugar and nucleotide sugar metabolism	COG0451	M
LFTS_00700	2342.58707328455	0.391011417605364	0.167497879459045	2.33442607672517	0.0195734226741366	0.0635433284403417	1446	NADH dehydrogenase subunit N	NADH dehydrogenase	K00343	 Energy metabolism	              Energy metabolism	               00190 Oxidative phosphorylation	COG1007	C
LFTS_00160	696.769789700055	0.441951562509967	0.189328292987743	2.33431335346471	0.0195793200262678	0.0635433284403417	303	DsrE/DsrF-like family protein	NA	K06039	NA	              Overview	               01210 2-Oxocarboxylic acid metabolism	COG1553	P
LFTS_00532	251.820165467867	-0.504808850239474	0.216973221852446	-2.32659517119017	0.0199868217936227	0.0647812763741148	1878	galactofuranosylgalactofuranosylrhamnosyl-N- acetylglucosaminyl-diphospho-decaprenol beta-1%2C5/1%2C6-galactofuranosyltransferase	Extracellular polysaccharide production and export	K07011	NA	              Metabolism of terpenoids and polyketides	               00523 Polyketide sugar unit biosynthesis	COG1216	G
LFTS_00400	657.205436551921	-0.37813137986942	0.163139299713984	-2.31784358846924	0.0204578232032559	0.0661268348839843	255	hypothetical protein	NA	K07330	NA	              Cellular community - prokaryotes	               02024 Quorum sensing	COG3354	N
LFTS_01438	782.538812966149	0.336514993491149	0.145188221926202	2.31778438379249	0.0204610422277088	0.0661268348839843	2037	ABC-type branched-chain amino acid transport system%2C substrate-binding protein	NA	K01999	 Cellular community - prokaryotes; Membrane transport	              Membrane transport	               02010 ABC transporters	COG0683	E
LFTS_01501	581.206976234315	0.357885475713962	0.154433821718602	2.31740347892235	0.0204817630171633	0.0661268348839843	774	phospholipid/cholesterol/gamma-HCH transport system ATP-binding protein	NA	K02065	 Membrane transport	              Membrane transport	               02010 ABC transporters	COG1127	M
LFTS_00082	200.725234023571	-0.5030319704765	0.217346777387033	-2.31442111322747	0.020644633858915	0.0665662253868518	900	CHAD domain-containing protein	NA	K07031	 Glycan biosynthesis and metabolism	              Glycan biosynthesis and metabolism	               00540 Lipopolysaccharide biosynthesis	COG2605	R
LFTS_00963	754.000811416541	0.327816089754256	0.141794371900999	2.31191185770854	0.0207825411390333	0.0669240897300995	1416	cobyrinic acid a%2Cc-diamide synthase	NA	K02224	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00860 Porphyrin and chlorophyll metabolism	COG1797	H
LFTS_00001	1379.37459486469	-0.410208629386481	0.17752169561761	-2.31075209122659	0.0208465521489039	0.0670433746988035	1398	chromosomal replication initiator protein DnaA	NA	K02313	 Cell growth and death; Signal transduction	              Signal transduction	               02020 Two-component system	COG0593	L
LFTS_01642	3068.05171690447	0.469208352877951	0.203196291138903	2.3091383718082	0.0209359040593373	0.067243743529086	759	methionine aminopeptidase%2C type I	NA	K01265	NA	              Translation	               03010 Ribosome	COG0024	J
LFTS_00172	602.136418929529	0.352724479318754	0.153057579538895	2.30452147735107	0.021193388140543	0.0679829198934064	873	diaminopimelate epimerase	NA	K01778	 Amino acid metabolism; Overview	              Overview	               01230 Biosynthesis of amino acids	COG0253	E
LFTS_01295	393.520161752991	0.380744569115887	0.165307835343372	2.30324574951342	0.0212650200928103	0.0681247937509362	906	hypothetical protein	NA	K09949	NA	              Glycan biosynthesis and metabolism	               00540 Lipopolysaccharide biosynthesis	COG3494	S
LFTS_02011	98.1708861469092	-0.573240865301891	0.249757355370375	-2.29519112440877	0.0217221736183074	0.0694997729924223	207	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00406	592.969487702253	-0.384038443372901	0.167813829001584	-2.28847911794728	0.0221096348239492	0.0706485246431077	1212	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_02501	907.127787380443	-0.302147089358917	0.132077029279567	-2.28765812652679	0.022157438015953	0.0706512126221021	1818	tRNA uridine 5-carboxymethylaminomethyl modification enzyme	NA	K03495	NA	              Translation	               00970 Aminoacyl-tRNA biosynthesis	COG0445	J
LFTS_01703	423.76707741429	0.377455424646723	0.16500865233127	2.28748868204164	0.0221673153037971	0.0706512126221021	1749	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00421	4155.46606833859	-0.42388454217775	0.185685218571489	-2.28281252239016	0.0224414140204605	0.0714332333609025	1215	cysteine desulfurase	Nitrogenase genes	K04487	 Metabolism of cofactors and vitamins; Folding, sorting and degradation	              Metabolism of cofactors and vitamins	               00730 Thiamine metabolism	COG1104	E
LFTS_01189	106.322835182367	-0.563864828564415	0.247256299562667	-2.2804872092713	0.0225788085443207	0.0717786675718431	771	Molybdopterin or thiamine biosynthesis adenylyltransferase	NA	K11996	 Folding, sorting and degradation	              Folding, sorting and degradation	               04122 Sulfur relay system	COG0476;COG0607	HP
LFTS_01689	1508.56683789528	0.402820887946413	0.176877747502622	2.27739720588901	0.0227625168101318	0.0722702640996012	1095	GTP-binding protein	NA	K06942	NA	              Translation	               03010 Ribosome	COG0012	J
LFTS_01804	395.171263805617	0.412464950669435	0.181194041101442	2.27637149744078	0.0228237841235284	0.0723723562896578	837	Transposase (or an inactivated derivative)	NA	K07493	NA	              Overview	               01200 Carbon metabolism	COG3328	X
LFTS_00166	478.624713532084	-0.34107869290835	0.149966159151964	-2.27437106369262	0.0229436857253711	0.0726598760678631	1143	membrane fusion protein%2C Cu(I)/Ag(I) efflux system	Copper/silver resistance	K07798	 Signal transduction	              Signal transduction	               02020 Two-component system	COG0845	MV
LFTS_00542	141.309136810099	-0.512427491007237	0.225913194892177	-2.2682494984492	0.0233140040771986	0.0737386948294095	1803	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00283	1528.10847817228	0.370120021648827	0.163271083762534	2.26690491126487	0.023396035148036	0.07390412119189	315	Heme-degrading monooxygenase HmoA	NA	K07145	NA	              Signal transduction	               02020 Two-component system	COG2329	H
LFTS_00854	550.414690194404	0.35468470748436	0.156509655850369	2.26621613572172	0.0234381531762156	0.0739248884486363	2748	hypothetical protein	NA	K09118	NA	              Amino acid metabolism	               00270 Cysteine and methionine metabolism	COG1615	S
LFTS_01397	24.6612325683703	-0.89059280048183	0.393082754697634	-2.26566235694285	0.0234720639799226	0.0739248884486363	120	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00902	504.559733736006	-0.404834531663529	0.178708061143228	-2.2653400695734	0.0234918189358096	0.0739248884486363	885	tRNA dimethylallyltransferase	NA	K00791	 Metabolism of terpenoids and polyketides	              Metabolism of terpenoids and polyketides	               00908 Zeatin biosynthesis	COG0324	J
LFTS_01271	75.2811415666353	-0.65095400829259	0.288132841966973	-2.25921489493796	0.0238700207405577	0.0749447895873784	273	Nucleotidyl transferase AbiEii toxin%2C Type IV TA system	NA	NA	NA	NA	NA	NA	NA
LFTS_00300	1164.06289747593	0.399199206379341	0.176705993475055	2.25911525992294	0.0238762161517312	0.0749447895873784	627	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01667	2620.20509298272	0.389280363100313	0.172365117880436	2.25846370708454	0.0239167647921094	0.0749572385528638	525	large subunit ribosomal protein L10	NA	K02864	 Translation	              Translation	               03010 Ribosome	COG0244	J
LFTS_00819	1374.44120352184	0.301448311374104	0.13349744549371	2.2580829937177	0.0239404856842212	0.0749572385528638	1173	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_02057	3941.06160914676	-0.269442713443708	0.119373233781508	-2.25714513135229	0.0239990076037057	0.075045953336871	1032	Site-specific recombinase XerD	NA	K14059	NA	              Translation	               03010 Ribosome	COG0582	LX
LFTS_02320	369.415395332644	0.369508413631714	0.163832418767056	2.25540473865002	0.024107935583736	0.0752918691723214	1209	putative ABC transport system permease protein	NA	K05685	 Membrane transport	              Membrane transport	               02010 ABC transporters	COG0577;COG1136	VM
LFTS_00545	181.656204339919	-0.433296572959664	0.19254941112046	-2.25031367501088	0.0244290404640817	0.0761989894525812	1962	Glycosyltransferase involved in cell wall bisynthesis	Extracellular polysaccharide production and export	K02844	 Glycan biosynthesis and metabolism	              Glycan biosynthesis and metabolism	               00540 Lipopolysaccharide biosynthesis	COG0438	M
LFTS_02110	465.497142718821	0.363826372612937	0.161743432029968	2.24940430685017	0.0244867848468878	0.0762833923926857	441	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily protein	NA	K07104	 Xenobiotics biodegradation and metabolism; Overview	              Overview	               01220 Degradation of aromatic compounds	COG2514	Q
LFTS_01860	184.238520648714	-0.438664486571269	0.195141441228922	-2.24793095617587	0.02458059287238	0.0764797920910345	318	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_02522	589.35183017924	0.367891359044014	0.163786578780828	2.24616303596102	0.0246935669271169	0.0767352592260157	1152	phosphate transport system substrate-binding protein	NA	K02040	 Membrane transport; Signal transduction; Infectious diseases	              Membrane transport	               02010 ABC transporters	COG0226	P
LFTS_01850	68.6314284070776	-0.626534370557349	0.279938910666722	-2.23811105453383	0.0252138139494678	0.0782541092114569	225	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01584	1858.91084465314	-0.273400391472386	0.122235001471733	-2.23667843236875	0.0253073646084536	0.0784465192227127	882	TIGR00255 family protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00015	1132.05499882973	0.342145590205111	0.153312719819817	2.23168430256291	0.0256358354484876	0.0793657371418932	786	putative transposase	NA	K07497	NA	              Replication and repair	               03410 Base excision repair	COG2801	X
LFTS_01372	627.738965405621	-0.34997234132217	0.156861517065561	-2.23109114248779	0.0256750923563534	0.0793884074600679	1314	Adenylosuccinate lyase	NA	K01756	 Amino acid metabolism; Nucleotide metabolism	              Nucleotide metabolism	               00230 Purine metabolism	COG0015	F
LFTS_00576	164.533580694484	-0.498640627436705	0.223559911883161	-2.23045636060775	0.0257171614937208	0.079419706178124	642	PEP-CTERM protein-sorting domain-containing protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00968	587.521843326871	0.335002835576379	0.150345575936168	2.22821877857325	0.0258659294257918	0.0797800254994025	2400	diguanylate cyclase (GGDEF) domain-containing protein	Genes encoding proteins with EAL and GGDEF domains	K14051	 Cellular community - prokaryotes	              Cellular community - prokaryotes	               02024 Quorum sensing	COG2199;COG2200;COG2202	T
LFTS_00354	231.906862239385	-0.55002133432861	0.247492089045721	-2.222379456448	0.0262576724896199	0.0808879477189531	132	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01319	224.628448052612	0.406008924968935	0.182909778294011	2.21972236124147	0.0264376199662798	0.0813414891536776	762	Diacylglycerol kinase family enzyme	NA	K07029	 Lipid metabolism	              Lipid metabolism	               00561 Glycerolipid metabolism	COG1597	IR
LFTS_00544	122.243847220959	-0.529360410494835	0.238643483195748	-2.21820601763772	0.0265407886318073	0.0815579734717837	1125	Glycosyltransferase involved in cell wall bisynthesis	Extracellular polysaccharide production and export	K02844	 Glycan biosynthesis and metabolism	              Glycan biosynthesis and metabolism	               00540 Lipopolysaccharide biosynthesis	COG0438	M
LFTS_01283	184.780720673427	-0.473061532076183	0.213514638220905	-2.21559297300613	0.0267193905522	0.0820054381639125	1104	DnaJ domain-containing protein	NA	K03686	NA	              Amino acid metabolism	               00270 Cysteine and methionine metabolism	COG0484	O
LFTS_01844	279.29303137504	0.497256454548513	0.224685933037638	2.21311787447421	0.0268895200940024	0.0824258285495561	777	Tetratricopeptide repeat protein	NA	NA	NA	NA	NA	NA	NA
LFTS_02409	1647.83212901617	-0.369165534264334	0.167237032066178	-2.2074389248803	0.0272834094825883	0.0835302413469391	888	Heat shock protein. Metallo peptidase. MEROPS family M48B	NA	K03799	NA	              Energy metabolism	               00190 Oxidative phosphorylation	COG0501	O
LFTS_00398	96.571469504292	-0.583630950331178	0.264898246829167	-2.2032269270078	0.0275787583367905	0.0842473174419584	492	Fe-S-cluster containining protein	NA	K06940	NA	              Signal transduction	               02020 Two-component system	COG0727	R
LFTS_01590	1115.10120681621	-0.317805847851853	0.144251802815289	-2.20313258932921	0.027585404826128	0.0842473174419584	450	3-dehydroquinate dehydratase	NA	K03786	 Overview; Amino acid metabolism	              Overview	               01230 Biosynthesis of amino acids	COG0757	E
LFTS_02289	276.461768239274	0.535119591493711	0.243059660984823	2.20159770373054	0.0276937382830713	0.0844743967751108	165	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01836	217.473296932079	-0.473374931712724	0.215348876427645	-2.19817692836569	0.0279365001367918	0.0851104648775298	927	3-hydroxyisobutyrate dehydrogenase	NA	K00020	 Amino acid metabolism	              Amino acid metabolism	               00280 Valine, leucine and isoleucine degradation	COG2084	I
LFTS_02113	270.414894055688	-0.376246912623933	0.171264456390932	-2.1968768100084	0.0280292454649553	0.0852884996644785	840	Sir2 family protein	NA	K12410	NA	              Overview	               01220 Degradation of aromatic compounds	COG0846	O
LFTS_02111	283.13720760512	0.372641789904051	0.169736622612111	2.19541183375391	0.0281340690045101	0.0854008067279777	354	DNA-binding transcriptional regulator%2C ArsR family	NA	K03892	NA	              Amino acid metabolism	               00270 Cysteine and methionine metabolism	COG0640	K
LFTS_01419	271.259381812217	0.481181111440432	0.219176885862908	2.19540080399447	0.0281348594972702	0.0854008067279777	249	ORF6N domain-containing protein	NA	K06678	 Cell growth and death	              Cell growth and death	               04111 Cell cycle - yeast	NA	
LFTS_01752	18.2368184823174	-0.876663481733366	0.399690634087679	-2.19335507756996	0.0282818062455226	0.0857421589345966	663	hydrogenase-4 component E	NA	K12140	NA	              Amino acid metabolism	               00260 Glycine, serine and threonine metabolism	NA	
LFTS_01657	2168.42242510526	0.369565746016574	0.168633459872382	2.19153272604532	0.0284132641964186	0.0860357792841617	657	large subunit ribosomal protein L4	NA	K02926	 Translation	              Translation	               03010 Ribosome	COG0088	J
LFTS_01311	305.09083716225	0.370089914729394	0.169067927337568	2.18900131182454	0.0285967446717209	0.0864860185570536	999	heptosyltransferase-2	Lipopolysaccharide synthesis	K02843	 Glycan biosynthesis and metabolism	              Glycan biosynthesis and metabolism	               00540 Lipopolysaccharide biosynthesis	COG0859	M
LFTS_00106	390.528675254539	0.385594637607768	0.176485857642414	2.18484723228668	0.0289000495907188	0.0872971121294375	1266	glutamate-5-semialdehyde dehydrogenase	NA	K00147	 Amino acid metabolism; Overview; Biosynthesis of other secondary metabolites	              Overview	               01230 Biosynthesis of amino acids	COG0014	E
LFTS_00499	1277.91401294122	0.470746200103366	0.215675491924646	2.18265967960717	0.0290608812977988	0.0876763967309804	1680	maltose alpha-D-glucosyltransferase/ alpha-amylase	NA	K05343	 Carbohydrate metabolism	              Carbohydrate metabolism	               00500 Starch and sucrose metabolism	COG0366	G
LFTS_00540	88.1613737624466	-0.56090216246511	0.257651990849673	-2.17697585264291	0.0294823691668875	0.0888402057562209	990	Glycosyltransferase%2C GT2 family	Extracellular polysaccharide production and export	K07011	NA	              Cell motility	               02030 Bacterial chemotaxis	COG1216	G
LFTS_00321	66.3090888032735	-0.668787844694618	0.30774490412659	-2.17318901377978	0.0297660943084123	0.0895865743955364	354	small multidrug resistance family-3 protein	NA	K09771	NA	              Signal transduction	               02020 Two-component system	COG1742	R
LFTS_00864	2048.45585143869	0.277161292480156	0.127658848518434	2.17110913733593	0.0299229235034242	0.0899496829861096	285	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_02173	820.024785725256	0.30710963047059	0.141595387479156	2.16892397371206	0.030088456317818	0.0903380463841734	1674	Formate-tetrahydrofolate ligase	NA	K01938	 Metabolism of cofactors and vitamins; Energy metabolism; Overview	              Overview	               01200 Carbon metabolism	COG2759	F
LFTS_00494	198.28331883438	-0.510467512147952	0.235461165718516	-2.16794778277024	0.030162659713996	0.0904515947515006	471	phosphohistidine phosphatase%2C SixA	NA	K08296	NA	              Carbohydrate metabolism	               00500 Starch and sucrose metabolism	COG2062	T
LFTS_01512	2766.94253245865	0.384093550712925	0.17736679179343	2.16553249246487	0.0303469298666134	0.0908546330698496	1146	aspartate aminotransferase	NA	K00839	 Nucleotide metabolism	              Nucleotide metabolism	               00230 Purine metabolism	COG0075	EF
LFTS_01196	48.3523620344478	-0.678789492305027	0.313495474975035	-2.16522899528002	0.0303701528885942	0.0908546330698496	1224	molybdopterin molybdotransferase	NA	K03750	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00790 Folate biosynthesis	COG0303	H
LFTS_01911	2393.25896234238	0.413902626795659	0.191572997190065	2.16054784790475	0.0307302837135195	0.0917107595126643	636	Transglycosylase SLT domain-containing protein	NA	K08309	NA	              Nucleotide metabolism	               00240 Pyrimidine metabolism	COG0741	M
LFTS_02189	910.969533333235	-0.323343417910845	0.149677276690929	-2.16027058388109	0.0307517287855171	0.0917107595126643	756	creatinine amidohydrolase	NA	K01470	 Amino acid metabolism	              Amino acid metabolism	               00330 Arginine and proline metabolism	COG1402	HQ
LFTS_01904	179.410220687949	0.433530352148274	0.200744469552725	2.15961293037967	0.0308026465930338	0.0917107595126643	552	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_02025	118.417300113649	-0.492842162113296	0.228210265695029	-2.15959681135428	0.030803895491985	0.0917107595126643	333	Cupin domain-containing protein	NA	K07167	NA	              Folding, sorting and degradation	               04122 Sulfur relay system	COG3806	T
LFTS_00059	383.889194931371	0.369594808046444	0.171280381662995	2.15783503316594	0.0309406600395617	0.0919507921449169	747	phosphoglycolate phosphatase	NA	K01091	 Carbohydrate metabolism	              Carbohydrate metabolism	               00630 Glyoxylate and dicarboxylate metabolism	COG0546	C
LFTS_00947	625.010419077582	-0.345890264692886	0.160312075282774	-2.15760580781436	0.0309584927696281	0.0919507921449169	570	molecular chaperone GrpE	NA	K03687	NA	              Folding, sorting and degradation	               03018 RNA degradation	COG0576	O
LFTS_00837	649.6646848492	0.385319942601934	0.179021821855363	2.15236298350961	0.0313687767559796	0.0930582088488847	768	Phospholipid methyltransferase	NA	K16168	NA	              Immune system	               04621 NOD-like receptor signaling pathway	COG1755	S
LFTS_01771	690.373698330594	-0.425452207279431	0.197827208883988	-2.15062533450052	0.0315057840109181	0.0933532527427204	552	hypothetical protein	NA	K08760	 Digestive system	              Digestive system	               04975 Fat digestion and absorption	NA	
LFTS_00423	679.892444254666	-0.32467830509546	0.151096232061783	-2.14881801263382	0.0316488289585789	0.0936654628464608	1068	PLD-like domain-containing protein	NA	K06131	 Lipid metabolism	              Lipid metabolism	               00564 Glycerophospholipid metabolism	COG1502	I
LFTS_01772	156.555774527657	-0.441104505918227	0.205324106835925	-2.14833276382258	0.0316873298869928	0.093667897858578	660	transcriptional regulator%2C TetR family	NA	K16137	NA	              Nucleotide metabolism	               00230 Purine metabolism	COG1309	K
LFTS_00027	197.609032845077	-0.514074735726502	0.239349989366898	-2.14779510576238	0.0317300360028791	0.0936827428778592	189	Zn-finger domain of CDGSH type-containing protein	NA	NA	NA	NA	NA	NA	NA
LFTS_02265	549.822825687064	0.358519518718943	0.167211683674123	2.14410566798465	0.0320244210287194	0.0944397516932343	744	1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase	NA	K01814	 Overview; Amino acid metabolism	              Overview	               01230 Biosynthesis of amino acids	COG0106	E
LFTS_01700	1580.76983745914	0.261539124647558	0.122064185843107	2.14263604710167	0.0321423343038912	0.0946751695254425	612	ATP-dependent Clp protease%2C protease subunit	NA	K01358	 Aging; Cell growth and death	              Cell growth and death	               04112 Cell cycle - Caulobacter	COG0740	O
LFTS_02482	500.230658780336	-0.450486997385763	0.210501824667577	-2.14006219707202	0.0323497406157531	0.0951733197287128	321	hypothetical protein	NA	K03210	 Cellular community - prokaryotes; Folding, sorting and degradation; Membrane transport	              Folding, sorting and degradation	               03060 Protein export	COG1862	U
LFTS_01701	4204.55172391835	0.268301219480157	0.125408107168154	2.13942483894126	0.032401277062376	0.0952122633298662	1407	trigger factor	NA	K03545	NA	              Nucleotide metabolism	               00240 Pyrimidine metabolism	COG0544	O
LFTS_02508	318.308970284119	0.346287613109759	0.162000850416335	2.13756663758131	0.0325519319092625	0.0955420339154977	834	hypothetical protein	NA	K07043	NA	              Cell growth and death	               04112 Cell cycle - Caulobacter	COG1451	R
LFTS_01921	1786.89795892835	0.312107993855793	0.146097717314999	2.1362961693841	0.032655280923332	0.0957323447823154	600	pyrimidine operon attenuation protein / uracil phosphoribosyltransferase	NA	K02825	 Nucleotide metabolism	              Nucleotide metabolism	               00240 Pyrimidine metabolism	COG2065	F
LFTS_01443	993.125053587325	0.335949109205383	0.157326814562529	2.13535823590874	0.0327317593642328	0.0958435262420292	1950	DNA helicase-2 / ATP-dependent DNA helicase PcrA	NA	K03657	 Replication and repair	              Replication and repair	               03420 Nucleotide excision repair	COG0210	L
LFTS_00501	858.519972925003	0.34754149767739	0.162850764226723	2.13411032688516	0.032833750744301	0.0960290639415673	1161	diguanylate cyclase (GGDEF) domain-containing protein	Putative diguanylate cyclases (GGDEF domain-containing proteins)	K13069	NA	              Signal transduction	               02020 Two-component system	COG2199	T
LFTS_01893	2106.68014233761	-0.271123366263603	0.127184247283619	-2.13173700402536	0.0330284729782439	0.0964850573724022	540	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00267	372.205413543339	0.441168836074708	0.207148730104198	2.1297202056358	0.0331947198114463	0.0968568937221309	1131	Putative MetA-pathway of phenol degradation	NA	NA	NA	NA	NA	NA	NA
LFTS_01004	376.550173159898	-0.34094906044945	0.160730755451375	-2.12124343901684	0.0339013214485241	0.0988026789226624	186	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_02103	1220.66412280253	-0.326050510086622	0.153941295207841	-2.11801849300028	0.0341735015363926	0.0994793030672976	447	aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C	NA	K02435	 Translation	              Translation	               00970 Aminoacyl-tRNA biosynthesis	COG0721	J
LFTS_02290	2051.32900481224	0.496560206656123	0.235328701131012	2.11007074049875	0.0348522631087985	0.101336521740904	1119	phosphate ABC transporter substrate-binding protein%2C PhoT family (TC 3.A.1.7.1)	NA	K02040	 Membrane transport; Signal transduction; Infectious diseases	              Membrane transport	               02010 ABC transporters	COG0226	P
LFTS_01927	383.153022851071	0.372333719071411	0.176587072554283	2.10849930114197	0.0349878231456819	0.101416406595651	507	hypothetical protein	NA	K14205	 Infectious diseases; Drug resistance; Signal transduction	              Signal transduction	               02020 Two-component system	COG0392;COG2898	S
LFTS_00674	576.648805603709	0.377160108413389	0.178920231888754	2.10797909454921	0.0350327977712729	0.101416406595651	336	hypothetical protein	NA	K15146	 Endocrine system	              Endocrine system	               04919 Thyroid hormone signaling pathway	NA	
LFTS_00728	183.477586045934	-0.472739268406471	0.22426913205551	-2.10791054512781	0.0350387279119261	0.101416406595651	831	PEP-CTERM protein-sorting domain-containing protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00375	992.335816082908	0.347222698880718	0.164776535014224	2.10723389013336	0.0350973106405871	0.101416406595651	264	small subunit ribosomal protein S20	NA	K02968	 Translation	              Translation	               03010 Ribosome	COG0268	J
LFTS_02433	2214.98331070311	0.276587696892733	0.131265376499225	2.10708797909376	0.0351099541268975	0.101416406595651	1146	Xaa-Pro aminopeptidase	NA	K01262	NA	              Amino acid metabolism	               00360 Phenylalanine metabolism	COG0006	E
LFTS_00028	535.966813931673	-0.42394678198694	0.201216356460204	-2.10692008067836	0.0351245076745193	0.101416406595651	486	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00726	390.726817218407	-0.333814153090847	0.158560231297024	-2.10528296004771	0.0352666844937352	0.101708790778916	213	sulfur carrier protein	NA	K03154	 Folding, sorting and degradation	              Folding, sorting and degradation	               04122 Sulfur relay system	COG2104	H
LFTS_01996	997.345724294016	-0.339647084795124	0.161370560119133	-2.10476486258942	0.0353117812003643	0.101720843643228	1545	tRNA(Ile)-lysidine synthase	NA	K04075	NA	              Metabolism of cofactors and vitamins	               00740 Riboflavin metabolism	COG0037	J
LFTS_02098	529.35674366333	-0.328508130831491	0.156331467211767	-2.10135641077618	0.0356096912925558	0.102460292307053	501	Tetraheme cytochrome c subunit of nitrate or TMAO reductase	NA	K15876	 Energy metabolism	              Energy metabolism	               00910 Nitrogen metabolism	COG3005	C
LFTS_02396	3028.56590793109	0.318797698628735	0.151847870217597	2.09945452756038	0.0357768522950164	0.102822259890648	327	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00988	178.6701991459	0.506035172436868	0.241156189581671	2.09837107359623	0.0358723785063145	0.102893266668628	195	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_02069	472.531236533893	-0.446101947746562	0.2126081290035	-2.09823561233267	0.0358843371688258	0.102893266668628	1005	alcohol dehydrogenase%2C propanol-preferring	NA	K13953	 Amino acid metabolism; Carbohydrate metabolism; Metabolism of cofactors and vitamins; Xenobiotics biodegradation and metabolism; Lipid metabolism; Overview	              Overview	               01220 Degradation of aromatic compounds	COG1064	G
LFTS_00078	1627.94806053759	0.374971340024777	0.17892042032602	2.09574367946108	0.0361049348688726	0.103406530050711	780	carboxymethylenebutenolidase	NA	K01061	 Xenobiotics biodegradation and metabolism	              Xenobiotics biodegradation and metabolism	               00364 Fluorobenzoate degradation	COG0412	Q
LFTS_01895	488.787794348738	-0.325891643730597	0.155600991383492	-2.09440595996852	0.0362238323028199	0.103627672157434	1812	DNA ligase-1	NA	K10747	 Replication and repair	              Replication and repair	               03030 DNA replication	COG1793	L
LFTS_00839	1572.42028781265	0.316861686334846	0.151373347273816	2.09324621567416	0.0363271811175841	0.103803876158982	888	protease-4	Chaperones	K04773	NA	              Translation	               03010 Ribosome	COG0616	O
LFTS_01593	1005.25094066992	0.28160208644619	0.134808603616505	2.08890292527081	0.0367164624749482	0.104795781530105	1371	acetyl-CoA carboxylase%2C biotin carboxylase subunit	NA	K01961	 Carbohydrate metabolism; Overview; Energy metabolism; Lipid metabolism	              Overview	               01200 Carbon metabolism	COG0439	I
LFTS_00688	2979.44652880075	0.262133398776481	0.125785363534053	2.08397377414675	0.0371625528717337	0.105947369769645	537	NADH dehydrogenase subunit B	NADH dehydrogenase	K00331	 Energy metabolism	              Energy metabolism	               00190 Oxidative phosphorylation	COG0377	C
LFTS_00091	1654.6481783544	0.291076744579272	0.139849673278905	2.08135448410217	0.0374014715531055	0.106506366874021	528	translation initiation factor IF-3	NA	K02520	NA	              Translation	               00970 Aminoacyl-tRNA biosynthesis	COG0290	J
LFTS_00216	40.0651454380341	-0.833398593621437	0.401158853895514	-2.07747775109185	0.0377574866382938	0.107286848516066	270	flagellar biosynthetic protein FliQ	Motility	K02420	 Cell motility	              Cell motility	               02040 Flagellar assembly	COG1987	N
LFTS_01768	845.999992727579	-0.306378324525424	0.147479473419668	-2.07743028518682	0.0377618634157514	0.107286848516066	567	Endonuclease%2C Uma2 family (restriction endonuclease fold)	NA	NA	NA	NA	NA	NA	NA
LFTS_01421	138.711172764803	0.42885525102298	0.206497905569295	2.07680194063309	0.0378198430431496	0.10732891530282	225	hypothetical protein	NA	K05929	 Lipid metabolism	              Lipid metabolism	               00564 Glycerophospholipid metabolism	NA	
LFTS_01067	66.4993352336688	0.543178150390049	0.261746279268294	2.07520867883391	0.037967198628575	0.107624236933452	285	Homeodomain-like domain-containing protein	NA	K11686	NA	              Translation	               03010 Ribosome	COG0789	K
LFTS_02524	1369.22769247686	0.269812987904277	0.130051096569502	2.07466907255244	0.0380172156203788	0.107643277941073	1179	ribulose-bisphosphate carboxylase large chain	Calvin-Benson-Bassham cycle carbon dioxide fixation	K01601	 Carbohydrate metabolism; Energy metabolism; Overview	              Overview	               01200 Carbon metabolism	COG1850	G
LFTS_00884	1531.88747648878	0.295115324869485	0.142292201593479	2.07400912744757	0.0380784631804782	0.107694038073571	1206	chorismate synthase	NA	K01736	 Overview; Amino acid metabolism	              Overview	               01230 Biosynthesis of amino acids	COG0082	E
LFTS_00702	423.777561441705	0.367962069149921	0.177492587194061	2.07311231960133	0.0381618277457078	0.107807163381624	471	hypothetical protein	NA	K08216	NA	              Overview	               01220 Degradation of aromatic compounds	NA	
LFTS_02495	1072.24663583775	0.356622046999533	0.172260906138173	2.07024364955727	0.0384295335794178	0.108440204856337	798	exonuclease%2C DNA polymerase III%2C epsilon subunit family	NA	K02342	 Replication and repair; Nucleotide metabolism	              Nucleotide metabolism	               00230 Purine metabolism	COG0847	L
LFTS_02354	1307.10444717181	-0.284680174159364	0.137952928859229	-2.06360369811256	0.0390553066833498	0.110081057159646	1245	diaminopimelate decarboxylase	NA	K01586	 Amino acid metabolism; Overview	              Overview	               01230 Biosynthesis of amino acids	COG0019	E
LFTS_01358	1274.74709264799	-0.288223046794951	0.139802528736799	-2.0616440160219	0.039241640191125	0.110480993788377	1635	(R)-citramalate synthase	NA	K01649	 Amino acid metabolism; Overview; Carbohydrate metabolism	              Overview	               01210 2-Oxocarboxylic acid metabolism	COG0119	E
LFTS_01707	1252.20242842665	-0.296570229924018	0.144016334613371	-2.05928189132292	0.0394672421943957	0.110957476379577	831	6-phosphogluconolactonase	NA	K01057	 Carbohydrate metabolism; Overview	              Overview	               01200 Carbon metabolism	COG0363	G
LFTS_00699	2158.32765595308	0.392809627790516	0.19081999629598	2.05853493038135	0.0395388117438979	0.110957476379577	1503	NADH-quinone oxidoreductase subunit M	NADH dehydrogenase	K00342	 Energy metabolism	              Energy metabolism	               00190 Oxidative phosphorylation	COG1008	C
LFTS_02420	885.786057615916	0.408687780091906	0.198539325988078	2.05847268825949	0.0395447803991573	0.110957476379577	1368	two-component system%2C NtrC family%2C response regulator AtoC	NA	K07714	 Signal transduction	              Signal transduction	               02020 Two-component system	COG2204	T
LFTS_00232	832.996963889562	0.271199239447314	0.131886093211052	2.05631414840171	0.0397522454127788	0.111413846782602	561	hypothetical protein	NA	K13999	 Folding, sorting and degradation	              Folding, sorting and degradation	               04141 Protein processing in endoplasmic reticulum	NA	
LFTS_01612	2387.61811502086	-0.25360511189795	0.123652735021886	-2.05094623950747	0.0402721824541158	0.112743970248797	774	Ferredoxin-NADP reductase	NA	K00523	 Carbohydrate metabolism	              Carbohydrate metabolism	               00520 Amino sugar and nucleotide sugar metabolism	COG0543	HC
LFTS_01704	1797.83387478714	0.290450486985856	0.141729496666987	2.0493298418205	0.0404298724895927	0.113058113621066	1488	glucose-6-phosphate 1-dehydrogenase	NA	K00036	 Carbohydrate metabolism; Metabolism of other amino acids; Overview; Cancers	              Overview	               01200 Carbon metabolism	COG0364	G
LFTS_01437	530.708939642547	0.329808586469006	0.160982666358243	2.04872110724682	0.0404893940336606	0.113097341087281	399	hypothetical protein	NA	K09449	NA	NA	NA	NA	
LFTS_02003	55.7594880247685	0.621047183452397	0.303539793012937	2.04601570452388	0.0407548255823738	0.113710994834771	1173	Putative ammonia monooxygenase	NA	K07120	NA	              Membrane transport	               02060 Phosphotransferase system (PTS)	COG3180	R
LFTS_01156	81.4978909655693	-0.697240734310104	0.341040655645925	-2.04445048637835	0.0409090641043636	0.114013378210143	393	MerC mercury resistance protein	Mercury resistance	NA	NA	NA	NA	NA	NA
LFTS_01586	1874.32463763741	0.323315706946795	0.158294709902564	2.04249217896042	0.0411027344429406	0.114208422640511	708	guanylate kinase	NA	K00942	 Nucleotide metabolism	              Nucleotide metabolism	               00230 Purine metabolism	COG0194	F
LFTS_00888	1358.17751420494	0.270045364402144	0.132218162354097	2.04242261119111	0.0411096287355968	0.114208422640511	1266	GAF domain-containing protein	NA	K08484	 Membrane transport	              Membrane transport	               02060 Phosphotransferase system (PTS)	COG3605	T
LFTS_00777	413.547785852771	0.377123394473325	0.184698038252415	2.04183757467924	0.0411676456904606	0.114208422640511	999	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00316	51.4352001460088	-0.642299616601966	0.314612164746558	-2.04156001761528	0.041195194745037	0.114208422640511	705	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01989	1350.94428074042	-0.305926818250171	0.149872686306591	-2.04124464429992	0.0412265162207507	0.114208422640511	1560	Glutathionylspermidine synthase preATP-grasp	Spermidine	NA	NA	NA	NA	NA	NA
LFTS_02068	538.33847061789	-0.38930897186533	0.190754394848626	-2.04089123175521	0.0412616395498533	0.114208422640511	3195	DNA helicase/exodeoxyribonuclease V%2C gamma subunit	NA	K03583	 Replication and repair	              Replication and repair	               03440 Homologous recombination	COG1330	L
LFTS_00668	1013.22224651503	-0.276657042854037	0.135583020642092	-2.04049918303818	0.0413006323225339	0.114208422640511	2289	DNA segregation ATPase FtsK/SpoIIIE%2C S-DNA-T family	NA	K03466	NA	              Folding, sorting and degradation	               03018 RNA degradation	COG1674	D
LFTS_01589	4360.79840358382	0.263909494371	0.129464421667026	2.03847119519645	0.0415028325921414	0.114640046471182	1395	Tetratricopeptide repeat-containing protein	NA	K12600	 Folding, sorting and degradation	              Folding, sorting and degradation	               03018 RNA degradation	COG0457	R
LFTS_02239	2562.88488010705	0.296415714881082	0.14593249184654	2.03118381061284	0.0422363520364503	0.116536704952958	498	hypothetical protein	NA	K08973	NA	              Metabolism of cofactors and vitamins	               00785 Lipoic acid metabolism	COG1981	S
LFTS_00129	916.134864852205	0.333719133706089	0.164706755744649	2.02614113912526	0.0427503233776518	0.117824061992065	357	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01207	41.0130851566305	-0.720161777968499	0.355776100719362	-2.02419942349238	0.0429496368869202	0.118242300443946	276	putative HTH-type transcriptional regulator YbaQ	NA	K07728	NA	              Translation	               00970 Aminoacyl-tRNA biosynthesis	COG1395	K
LFTS_01843	1083.98520071575	-0.544907152270651	0.269340335261267	-2.02311752431019	0.0430610322014354	0.118417838553947	447	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00339	2100.2382093776	0.276458932165461	0.136802278243708	2.0208649718023	0.0432937448202934	0.118926242677624	690	proteasome alpha subunit	NA	K03432	 Folding, sorting and degradation	              Folding, sorting and degradation	               03050 Proteasome	COG0638	O
LFTS_00681	4196.72449239254	-0.239293274724554	0.118499592851749	-2.0193594675378	0.0434498711411732	0.119223377104809	1893	1-deoxy-D-xylulose-5-phosphate synthase	NA	K01662	 Metabolism of terpenoids and polyketides; Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00730 Thiamine metabolism	COG1154	HI
LFTS_01316	314.870297660885	-0.347832580352342	0.172663878229007	-2.01450693636688	0.043956337359719	0.120480104383971	723	Polysaccharide deacetylase	Lipopolysaccharide synthesis	K11931	 Cellular community - prokaryotes	              Cellular community - prokaryotes	               02026 Biofilm formation - Escherichia coli	COG0726	GM
LFTS_02383	419.378293137587	0.379760210137838	0.189023897734385	2.00905924959538	0.0445308506098693	0.121803703354655	1557	phospholipid/cholesterol/gamma-HCH transport system substrate-binding protein	NA	K02067	 Membrane transport	              Membrane transport	               02010 ABC transporters	COG1463	M
LFTS_00814	1134.77823456927	-0.283741833843049	0.141235424976575	-2.00899904461016	0.0445372350560665	0.121803703354655	1557	NAD(P)H-hydrate epimerase	NA	K12615	 Folding, sorting and degradation	              Folding, sorting and degradation	               03018 RNA degradation	NA	
LFTS_01864	402.523098784314	0.393213817092662	0.195974894839793	2.00644994561221	0.0448082640721088	0.122368686941045	984	Small-conductance mechanosensitive channel	NA	K16052	NA	              Glycan biosynthesis and metabolism	               00550 Peptidoglycan biosynthesis	COG0668	M
LFTS_00801	487.792333212924	-0.314556659882519	0.156797661584333	-2.0061310653752	0.0448422662121047	0.122368686941045	228	hypothetical protein	NA	K02027	NA	              Translation	               03010 Ribosome	COG1653;COG2182	G
LFTS_00402	919.939925426209	-0.294555197953879	0.146891184658128	-2.00526123224767	0.0449351270130433	0.122487637888625	372	hypothetical protein	NA	K02282	NA	              Translation	               00970 Aminoacyl-tRNA biosynthesis	COG4963	UW
LFTS_01487	2167.10452649826	0.293099544722626	0.146218240773795	2.00453475005258	0.0450128083248551	0.122564996161654	1362	NADH-quinone oxidoreductase subunit F	NADH dehydrogenase	K00335	 Energy metabolism	              Energy metabolism	               00190 Oxidative phosphorylation	COG1894	C
LFTS_00346	566.7102285078	0.360683375390948	0.180023230824868	2.00353795306469	0.0451195781178391	0.122721303283313	444	Sel1 repeat-containing protein	NA	K07126	NA	              Overview	               01210 2-Oxocarboxylic acid metabolism	COG0790	T
LFTS_02026	36.0519088262934	0.673135449228483	0.336236655016346	2.00196926535496	0.0452880371590924	0.123044874729512	300	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00170	687.154941291904	0.319524418895861	0.159819507223357	1.99928296893888	0.0455777458334183	0.12369680801515	744	NAD(P)-dependent dehydrogenase%2C short-chain alcohol dehydrogenase family	NA	K00059	 Lipid metabolism; Overview; Metabolism of cofactors and vitamins	              Overview	               01212 Fatty acid metabolism	COG1028	IQR
LFTS_01722	1048.46816626809	0.289452173683537	0.14487064148104	1.9980043625431	0.0457161871613078	0.123937231497286	1713	chloride channel protein%2C CIC family	NA	K03281	NA	              Folding, sorting and degradation	               03018 RNA degradation	COG0038	P
LFTS_01483	1446.39122557584	0.274530084814572	0.137691274244957	1.99380887656087	0.0461729451469831	0.125039152108279	714	CRP/FNR family transcriptional regulator%2C anaerobic regulatory protein	NA	K10914	 Cellular community - prokaryotes; Signal transduction	              Signal transduction	               02020 Two-component system	COG0664	T
LFTS_00931	221.008978403094	0.416753294853201	0.209442959112413	1.98981764113407	0.0466110273980544	0.12595270850399	291	preprotein translocase subunit YajC	NA	K03210	 Cellular community - prokaryotes; Folding, sorting and degradation; Membrane transport	              Folding, sorting and degradation	               03060 Protein export	COG1862	U
LFTS_01569	435.871131628919	-0.30612054799013	0.153843935997449	-1.9898122471022	0.0466116218116132	0.12595270850399	840	cobalt-precorrin 4 C11-methyltransferase	NA	K05936	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00860 Porphyrin and chlorophyll metabolism	COG2875	H
LFTS_00611	342.917649945111	-0.374736909710815	0.188932280179022	-1.98344565235615	0.0473176720265394	0.127601447272202	219	YggT family protein	NA	K02221	NA	              Overview	               01230 Biosynthesis of amino acids	COG0762	S
LFTS_00060	540.220450770213	0.292926889775764	0.147690375557345	1.98338509649213	0.047324430565153	0.127601447272202	495	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01108	92.3660965468623	0.506672631178216	0.255558573746061	1.98260861982145	0.0474111637919621	0.127696807352999	444	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01798	1101.95021957159	0.316218341373634	0.159562342967942	1.98178552339989	0.0475032503945865	0.127806364156864	786	putative transposase	NA	K07497	NA	              Infectious diseases	               05132 Salmonella infection	COG2801	X
LFTS_00332	1566.78239765727	-0.384792040001381	0.194265624928983	-1.98075207665818	0.0476190835215094	0.12792026372222	609	hypothetical protein	NA	K07337	NA	              Folding, sorting and degradation	               03050 Proteasome	COG3417	M
LFTS_00993	129.622903085849	-0.466383384367582	0.235488887710447	-1.98048998788019	0.0476484972674078	0.12792026372222	225	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_02428	1623.47400207589	0.286719625999946	0.144882166804988	1.97898493874592	0.0478177020199477	0.128174489335957	2154	Alpha-amylase/alpha-mannosidase%2C GH57 family	NA	K07405	 Carbohydrate metabolism	              Carbohydrate metabolism	               00500 Starch and sucrose metabolism	COG1449	G
LFTS_01817	198.301182463353	0.486681796144411	0.245956532673126	1.97873091987033	0.0478463097762542	0.128174489335957	111	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01236	63.8022860711613	0.536142003541124	0.271229507689954	1.97670971756507	0.0480744517500729	0.128526763448193	315	Cupin domain protein	NA	K00450	 Amino acid metabolism	              Amino acid metabolism	               00350 Tyrosine metabolism	NA	
LFTS_01794	267.939045218236	0.344286199026686	0.174176615013524	1.97664995958242	0.0480812107831134	0.128526763448193	300	Transposase (or an inactivated derivative)	NA	K07493	NA	              Signal transduction	               02020 Two-component system	COG3328	X
LFTS_00776	375.988498525007	0.347339483721129	0.17594272600485	1.97416222658477	0.0483632995821273	0.129141957853027	654	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01424	74.8419685717415	0.522014471078818	0.264521469281368	1.97342950081514	0.0484466492952779	0.129171508596027	417	Transposase	NA	K07485	NA	              Overview	               01200 Carbon metabolism	COG3464	X
LFTS_00761	1027.97603551392	-0.270770518169805	0.137227422959751	-1.97315166553279	0.0484782854063126	0.129171508596027	2703	long-chain acyl-CoA synthetase	NA	K01897	 Cell growth and death; Cellular community - prokaryotes; Transport and catabolism; Lipid metabolism; Endocrine system; Overview	              Overview	               01212 Fatty acid metabolism	COG0318;COG1022	IQ
LFTS_00080	43.4322813922272	0.690051299073057	0.349985143931438	1.97165882906229	0.0486485665651966	0.129486441628564	936	UDP-2%2C3-diacylglucosamine pyrophosphatase LpxH	Lipopolysaccharide synthesis	K03269	 Glycan biosynthesis and metabolism	              Glycan biosynthesis and metabolism	               00540 Lipopolysaccharide biosynthesis	COG2908	M
LFTS_00512	727.136447560439	-0.338206962089696	0.17166548048711	-1.97015125656023	0.0488210379949784	0.129806524551354	1212	Rhodopirellula transposase DDE domain-containing protein	NA	K07499	NA	              Signal transduction	               02020 Two-component system	COG3415	X
LFTS_02268	793.705846451282	0.30133358578939	0.1531017864715	1.96819118009105	0.0490460447065164	0.130265456346581	1080	histidinol-phosphate aminotransferase	NA	K00817	 Overview; Amino acid metabolism; Biosynthesis of other secondary metabolites	              Overview	               01230 Biosynthesis of amino acids	COG0079	E
LFTS_00288	601.04812768132	0.324993415167707	0.16517894646365	1.96752323540958	0.0491229198862123	0.130330393636205	834	serine protease%2C ClpP class	NA	K07403	NA	              Signal transduction	               02020 Two-component system	COG1030	O
LFTS_00845	1559.4772097631	0.335418091747287	0.170616327210976	1.96592024474026	0.0493078241290532	0.130681504034996	357	large subunit ribosomal protein L19	NA	K02884	 Translation	              Translation	               03010 Ribosome	COG0335	J
LFTS_00452	118.628834454943	0.625798195802586	0.318550920695063	1.96451542013165	0.0494703498153006	0.130972619425812	618	K+-transporting ATPase ATPase C chain	Role of potassium in the internal positive membrane potential	K01548	 Signal transduction	              Signal transduction	               02020 Two-component system	COG2156	P
LFTS_00135	103.278548611819	-0.480393733233156	0.244938603909223	-1.96128223794072	0.049846108113646	0.131693607399355	2169	hypothetical protein	NA	K02027	NA	              Signal transduction	               02020 Two-component system	COG1653;COG2182	G
LFTS_01130	156.967609330256	0.411858161705956	0.209996648643524	1.96126064090241	0.0498486261314534	0.131693607399355	975	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01418	316.697860036115	0.374576930322833	0.191093091501943	1.96018038841045	0.0499747098852762	0.131858579230404	225	ORF6N domain-containing protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01260	294.991032109211	0.331042881504095	0.168915177370968	1.95981726838593	0.0500171521376794	0.131858579230404	423	putative nucleic acid-binding protein%2C contains PIN domain	NA	K07064	NA	              Overview	               01200 Carbon metabolism	COG1848	R
LFTS_01802	283.660632065769	0.397170336339622	0.2033273696034	1.95335402761725	0.050777659664631	0.133721675769357	525	DNA replication protein DnaC	NA	K02315	NA	              Overview	               01200 Carbon metabolism	COG1484	L
LFTS_02208	342.464716676974	-0.354748446184946	0.182075471954199	-1.94835933900082	0.051371981518752	0.135143646619701	177	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00502	116.150350217152	-0.451221572925231	0.231742926258603	-1.94707808436712	0.0515253739899135	0.135403889787447	843	PEP-CTERM protein-sorting domain-containing protein	NA	K02568	 Energy metabolism	              Energy metabolism	               00910 Nitrogen metabolism	COG3043	CP
LFTS_02410	1642.03538956045	-0.302783019023456	0.155596690633421	-1.9459476791624	0.0516610248028635	0.135617009144581	960	methionyl-tRNA formyltransferase	NA	K00604	 Translation; Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00670 One carbon pool by folate	COG0223	J
LFTS_01153	67.9124079036553	-0.632326124140761	0.325227942256908	-1.94425521913264	0.051864681871706	0.136008015963145	540	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01338	864.784316746212	0.288202818967639	0.148470500641975	1.94114533002497	0.0522406520904019	0.136849590196775	1212	aspartate aminotransferase	NA	K00812	 Amino acid metabolism; Overview; Biosynthesis of other secondary metabolites	              Overview	               01210 2-Oxocarboxylic acid metabolism	COG0436	E
LFTS_00120	515.662248153707	0.31152500699131	0.160526812086012	1.94064158468674	0.0523017663872205	0.136865464461716	615	dephospho-CoA kinase	NA	K00859	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00770 Pantothenate and CoA biosynthesis	COG0237	H
LFTS_01656	1838.8468219146	0.442688305533403	0.228306141474168	1.93901181402731	0.0524998996256078	0.13705553970135	288	large subunit ribosomal protein L23	NA	K02892	 Translation	              Translation	               03010 Ribosome	COG0089	J
LFTS_01628	2000.4406165309	0.29811785860154	0.153768495738026	1.93874471601413	0.0525324308335796	0.13705553970135	1833	Putative Zn-dependent protease%2C contains TPR repeats	NA	K11739	NA	              Membrane transport	               03070 Bacterial secretion system	COG0457	R
LFTS_02490	979.220418731167	-0.363369793561593	0.187431134736232	-1.93868427501629	0.0525397945838241	0.13705553970135	447	hypothetical protein	NA	K08999	NA	              Folding, sorting and degradation	               04122 Sulfur relay system	COG1259	R
LFTS_01986	1065.20731293524	0.251932072687978	0.130072590973498	1.93685749474544	0.0527627654929702	0.137492908821304	1101	dCTP deaminase	NA	K01494	 Nucleotide metabolism	              Nucleotide metabolism	               00240 Pyrimidine metabolism	COG0717	F
LFTS_00249	433.657102942696	0.313110354944996	0.161705402721563	1.93630113573963	0.0528308297857471	0.137526118164782	1734	NitT/TauT family transport system permease protein	NA	K02050	NA	              Translation	               03010 Ribosome	COG0600	P
LFTS_00992	163.323805873213	-0.442407604839776	0.228736508952307	-1.93413638629949	0.0530963612275511	0.138035249436662	855	CRISPR/Cas system-associated exonuclease Cas4%2C RecB family	NA	K07465	NA	              Energy metabolism	               00920 Sulfur metabolism	COG2887	L
LFTS_01932	483.192952180846	0.377113259596523	0.195037883189455	1.93353851790016	0.0531698928612668	0.138035249436662	264	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00616	4781.56784409317	-0.216340633437471	0.11190791390797	-1.93320227214122	0.053211284977606	0.138035249436662	2052	squalene-hopene/tetraprenyl-beta-curcumene cyclase	NA	K06045	 Metabolism of terpenoids and polyketides	              Metabolism of terpenoids and polyketides	               00909 Sesquiterpenoid and triterpenoid biosynthesis	COG1657	I
LFTS_02205	863.087305171891	-0.268466269627147	0.138892992147406	-1.93290003675799	0.0532485133587124	0.138035249436662	984	Site-specific recombinase XerD	NA	K04763	NA	              Metabolism of cofactors and vitamins	               00130 Ubiquinone and other terpenoid-quinone biosynthesis	COG0582	LX
LFTS_00447	577.337261709329	0.417802723798365	0.21623822895506	1.9321408883958	0.053342118777307	0.138133861750401	1272	ADP-heptose:LPS heptosyltransferase	NA	K02843	 Glycan biosynthesis and metabolism	              Glycan biosynthesis and metabolism	               00540 Lipopolysaccharide biosynthesis	COG0859	M
LFTS_01490	365.485131746	-0.32094020150562	0.166582813109695	-1.92661052790771	0.0540281856364725	0.139764900616306	666	putative dithiol-disulfide isomerase%2C DsbA family	NA	K07396	NA	              Overview	               01200 Carbon metabolism	COG3531	O
LFTS_01830	687.192546837971	-0.341218489321035	0.177746128062705	-1.91969576519079	0.0548963394818406	0.141863097663052	2025	PAS domain S-box-containing protein	NA	K07710	 Signal transduction	              Signal transduction	               02020 Two-component system	COG0642	T
LFTS_02048	37.4237503529599	0.61426244037403	0.320140595847397	1.91872711034383	0.0550188786641203	0.142032120829702	285	Cu and Ag efflux protein CusF	Copper/silver resistance	K07810	 Signal transduction	              Signal transduction	               02020 Two-component system	COG5569	P
LFTS_02085	409.202723786558	-0.342160453943106	0.178613373644634	-1.91564857077199	0.0554098427463537	0.142893017704808	879	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_02293	118.307300331322	0.641492132655437	0.33539877141679	1.91262517136139	0.055796054881471	0.143739888534028	1644	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_02493	7805.2134068801	-0.42385633145206	0.221931723032658	-1.90985013615961	0.0561525118493693	0.144508431115458	138	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00749	1428.95265858418	-0.315307447617006	0.165314838671467	-1.90731485540522	0.0564798276462755	0.145200466937581	3246	Multidrug efflux pump subunit AcrB	NA	K03296	NA	              Overview	               01200 Carbon metabolism	COG0841	V
LFTS_00642	709.910609712109	-0.301928265712737	0.158413361178651	-1.90595201986932	0.0566564309648793	0.145466259128436	669	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00478	124.759128975564	-0.426902647500116	0.224023617721338	-1.90561446977049	0.0567002434012288	0.145466259128436	507	hypothetical protein	NA	K01850	 Overview; Amino acid metabolism	              Overview	               01230 Biosynthesis of amino acids	NA	
LFTS_02050	403.241294792765	0.352341011841608	0.185514653749123	1.89926242871406	0.0575299801586008	0.147442815128125	2319	Cu+-exporting ATPase	Copper resistance	K01533	NA	              Overview	               01200 Carbon metabolism	COG2217	P
LFTS_01431	100.212728561344	-0.480086600134341	0.253829079746702	-1.89137746003501	0.058573975226285	0.149957335253123	654	Transposase DDE domain group 1	NA	NA	NA	NA	NA	NA	NA
LFTS_00353	358.41808775069	0.35018056738319	0.18518817578572	1.89094452654677	0.0586317497449862	0.149957335253123	459	hypothetical protein	NA	K08976	NA	              Amino acid metabolism	               00260 Glycine, serine and threonine metabolism	COG2322	S
LFTS_01534	2297.20352235794	0.327496424069505	0.173311716711601	1.88963810574027	0.0588063771637244	0.150249387080184	1023	3-deoxy-D-arabinoheptulosonate-7-phosphate synthase	NA	K03856	 Overview; Amino acid metabolism	              Overview	               01230 Biosynthesis of amino acids	COG2876	E
LFTS_01046	126.121285847292	0.401353504024759	0.213143663983119	1.88301869511142	0.0596978344436669	0.152248274676795	1932	Streptogramin lyase	NA	K01053	 Carbohydrate metabolism; Xenobiotics biodegradation and metabolism; Overview	              Overview	               01200 Carbon metabolism	COG3386	G
LFTS_00329	399.525166010843	-0.336381750048805	0.178648986369887	-1.88292000354447	0.0597112098993866	0.152248274676795	1005	alcohol dehydrogenase%2C propanol-preferring	NA	K13953	 Amino acid metabolism; Carbohydrate metabolism; Metabolism of cofactors and vitamins; Xenobiotics biodegradation and metabolism; Lipid metabolism; Overview	              Overview	               01220 Degradation of aromatic compounds	COG1064	G
LFTS_00335	5839.0144775037	-0.287424463544665	0.153035318503867	-1.87815771126978	0.0603595933387245	0.153743800245973	1740	proteasome-associated ATPase	NA	K13527	 Folding, sorting and degradation	              Folding, sorting and degradation	               03050 Proteasome	COG0464	MDT
LFTS_02049	81.4369013278114	0.507629163051045	0.270387493056771	1.87741362336039	0.0604614257448834	0.153845552100082	306	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01371	371.373309590607	-0.327649867299278	0.174706954883951	-1.87542543751003	0.0607342183462231	0.15438166340359	501	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00739	46.9409507931518	-0.564187795424576	0.301016952490481	-1.87427249780033	0.0608928761475258	0.154626854037537	2238	cellulose synthase (UDP-forming)	Cellulose production	K00694	 Carbohydrate metabolism; Cellular community - prokaryotes	              Carbohydrate metabolism	               00500 Starch and sucrose metabolism	COG1215	N
LFTS_01754	57.4322954054524	-0.594996560434026	0.317541131722984	-1.8737621712361	0.060963212518451	0.154647496245785	1500	Ni%2CFe-hydrogenase III large subunit	NA	K00333	 Energy metabolism	              Energy metabolism	               00190 Oxidative phosphorylation	COG0649	C
LFTS_01320	559.142569394586	0.334223206552521	0.178718360243027	1.87011119673453	0.0614683779492673	0.155770017922404	870	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_02530	317.317229400106	0.355298418174174	0.190140040546087	1.8686144020678	0.0616764805964754	0.156138218699427	426	glyoxylase I family protein	NA	K08234	NA	              Overview	               01200 Carbon metabolism	COG0346	Q
LFTS_00487	872.814293021424	-0.363358039054947	0.194537535498895	-1.86780426781449	0.06178935837582	0.156264847326845	1398	3-isopropylmalate dehydratase%2C large subunit	NA	K01702	 Amino acid metabolism; Overview	              Overview	               01210 2-Oxocarboxylic acid metabolism	COG0065;COG0066	E
LFTS_01494	26786.7851505403	0.242556104082821	0.130008858843953	1.86568904795908	0.0620848828347705	0.15685266130817	1239	40-residue YVTN family beta-propeller repeat-containing protein	NA	K01053	 Carbohydrate metabolism; Xenobiotics biodegradation and metabolism; Overview	              Overview	               01200 Carbon metabolism	COG3386	G
LFTS_00690	7163.51451215701	0.305580807886387	0.163873430025892	1.86473675346946	0.0622183123661084	0.157030177200148	1272	NADH-quinone oxidoreductase subunit D	NADH dehydrogenase	K00333	 Energy metabolism	              Energy metabolism	               00190 Oxidative phosphorylation	COG0649	C
LFTS_01726	798.526479915459	-0.349657469161096	0.187885610239189	-1.8610124996585	0.0627424115399043	0.158082404813315	261	hypothetical protein	NA	K06400	NA	              Replication and repair	               03030 DNA replication	COG1961	L
LFTS_00293	2182.74135538707	0.358388417629354	0.192627633699777	1.86052442604329	0.0628113659305534	0.158082404813315	1503	serine protease Do	Oxidative stress response	K04772	NA	              Replication and repair	               03440 Homologous recombination	COG0265	O
LFTS_01521	752.393837288374	-0.305073825848643	0.163981073579509	-1.86042095706077	0.0628259919370698	0.158082404813315	1125	membrane fusion protein%2C Cu(I)/Ag(I) efflux system	Copper/silver resistance; Cadmium/cobalt/zinc resistance	K07798	 Signal transduction	              Signal transduction	               02020 Two-component system	COG0845	MV
LFTS_02076	1078.1688719153	-0.254552698675046	0.136888774525372	-1.85955860557336	0.0629480004323601	0.158105164277054	969	diguanylate cyclase (GGDEF) domain-containing protein	Putative diguanylate cyclases (GGDEF domain-containing proteins)	K13069	NA	              Signal transduction	               02020 Two-component system	COG2199	T
LFTS_02443	2507.60597587436	-0.281109363485632	0.15117811153392	-1.85945809636973	0.0629622335616587	0.158105164277054	1542	L-aspartate oxidase	NA	K00278	 Amino acid metabolism; Metabolism of cofactors and vitamins	              Amino acid metabolism	               00250 Alanine, aspartate and glutamate metabolism	COG0029	H
LFTS_01155	162.065418405267	-0.568807152888119	0.305983458310679	-1.85894739548497	0.0630345951285875	0.158127147820049	432	MerR family transcriptional regulator%2C Zn(II)-responsive regulator of zntA	NA	K13638	NA	              Signal transduction	               02020 Two-component system	COG0789	K
LFTS_00568	436.935887825857	-0.279937872800186	0.150838275621687	-1.85588088730403	0.0634705378029416	0.159060238889227	1557	PilZ domain-containing protein	c-di-GMP effector proteins; Extracellular polysaccharide production and export	K02481	NA	              Metabolism of cofactors and vitamins	               00860 Porphyrin and chlorophyll metabolism	COG2204	T
LFTS_01773	137.822587913418	-0.433040414263756	0.233511203912219	-1.85447381970821	0.0636714022807251	0.159265128193837	363	DsrE/DsrF-like family protein	NA	K07092	NA	              Translation	               03010 Ribosome	COG2044	R
LFTS_01686	1065.92936870601	0.277437673004834	0.149609616253878	1.8544106986682	0.06368042535184	0.159265128193837	231	small subunit ribosomal protein S18	NA	K02963	 Translation	              Translation	               03010 Ribosome	COG0238	J
LFTS_02137	565.561467182194	0.302897498054635	0.163435117329572	1.85331954970138	0.0638365707069507	0.159495190731135	1956	basic amino acid/polyamine antiporter%2C APA family	NA	K03294	NA	              Translation	               03010 Ribosome	COG0531	E
LFTS_00422	2358.27507875533	-0.376439017029855	0.203220213296527	-1.85236995337948	0.0639727168475578	0.159674873577338	471	transcriptional regulator%2C BadM/Rrf2 family	NA	K13643	NA	              Lipid metabolism	               00564 Glycerophospholipid metabolism	COG1959	K
LFTS_02261	7048.97911544759	0.254380848671926	0.137425169648997	1.85104991554057	0.0641623724225682	0.15985451470637	309	DNA-binding protein HU-beta	NA	K03530	NA	              Overview	               01230 Biosynthesis of amino acids	COG0776	L
LFTS_02528	260.684919890357	0.382987213469769	0.206939182894487	1.85072352230677	0.0642093382719216	0.15985451470637	1137	Putative MetA-pathway of phenol degradation	NA	NA	NA	NA	NA	NA	NA
LFTS_01655	3387.63586883766	0.313846884807001	0.169598629387869	1.85052724741802	0.0642375946064618	0.15985451470637	822	LSU ribosomal protein L2P	NA	K02886	 Translation	              Translation	               03010 Ribosome	COG0090	J
LFTS_00604	789.478058615357	0.295601130855908	0.160158306811216	1.84568091871964	0.0649385493942015	0.161294817472551	948	D-alanine--D-alanine ligase	NA	K01921	 Metabolism of other amino acids; Glycan biosynthesis and metabolism; Drug resistance	              Metabolism of other amino acids	               00473 D-Alanine metabolism	COG1181	MR
LFTS_00904	1434.46136134945	0.225394992890874	0.122123696254851	1.84562865195722	0.0649461433185936	0.161294817472551	942	Sugar or nucleoside kinase%2C ribokinase family	NA	K00852	 Carbohydrate metabolism	              Carbohydrate metabolism	               00030 Pentose phosphate pathway	COG0524	G
LFTS_01282	235.555234965631	-0.33081732977236	0.179509885307283	-1.84289199007659	0.0653447820197469	0.162122882336418	1014	hypothetical protein	NA	K07337	NA	              Amino acid metabolism	               00270 Cysteine and methionine metabolism	COG3417	M
LFTS_02274	1188.85372341269	0.322981102837829	0.175307565977798	1.84236830302426	0.0654212949709889	0.162150886637964	207	LSU ribosomal protein L31P	NA	K02909	 Translation	              Translation	               03010 Ribosome	COG0254	J
LFTS_01471	50.9696544376385	0.53463545882007	0.290371153696942	1.84121408760205	0.0655901917039474	0.162407586231089	849	MoxR-like ATPase	NA	K03924	NA	              Nucleotide metabolism	               00230 Purine metabolism	COG0714	R
LFTS_00281	494.030289033339	-0.33437989941965	0.18243431683252	-1.83287829409102	0.0668206723756254	0.165289742811746	936	Radical SAM superfamily protein	NA	K06871	NA	              Metabolism of cofactors and vitamins	               00730 Thiamine metabolism	COG0641	O
LFTS_01213	100.455194706155	-0.429531873293657	0.234479724524119	-1.83185080998111	0.0669736508630933	0.165422106028045	276	addiction module antidote protein%2C HigA family	NA	K07729	NA	              Signal transduction	               02020 Two-component system	COG1476	K
LFTS_02287	579.509308498571	0.399676737638093	0.21820878861617	1.83162529874599	0.0670072649920522	0.165422106028045	912	phosphate transport system permease protein	NA	K02038	 Membrane transport	              Membrane transport	               02010 ABC transporters	COG0581	P
LFTS_02312	156.908811013143	0.37809327037902	0.206589298347077	1.83016871350136	0.0672247145776918	0.165794286150934	1227	Major Facilitator Superfamily protein	NA	K05820	NA	              Signal transduction	               02020 Two-component system	COG0477	GEPR
LFTS_00184	1747.26850727374	-0.249522377871134	0.136412190228179	-1.82917947035198	0.0673727268597096	0.165994647148898	705	peptidyl-prolyl cis-trans isomerase D	NA	K03770	NA	              Signal transduction	               02020 Two-component system	COG0760	O
LFTS_01998	11962.6836256885	-0.205584294856604	0.112481153046171	-1.82772214979176	0.0675912621401746	0.166368195723242	1800	cell division protease FtsH	NA	K03798	NA	              Metabolism of cofactors and vitamins	               00860 Porphyrin and chlorophyll metabolism	COG0465	O
LFTS_01281	248.341375258915	-0.330518108875389	0.181083080106902	-1.82522910854105	0.0679664629105389	0.167101216042844	783	putative phosphoesterase	NA	K07096	NA	              Amino acid metabolism	               00270 Cysteine and methionine metabolism	COG2129	R
LFTS_02471	937.949784208661	0.278683128947504	0.152715545216382	1.82485108868674	0.068023503875848	0.167101216042844	1068	Phosphotransferase enzyme family protein	NA	K07102	 Carbohydrate metabolism	              Carbohydrate metabolism	               00520 Amino sugar and nucleotide sugar metabolism	COG3178	R
LFTS_01577	640.66954305695	0.267946633159794	0.146910106562398	1.82388155198831	0.0681699812289343	0.167295728859951	1239	diguanylate cyclase (GGDEF) domain-containing protein	Putative diguanylate cyclases (GGDEF domain-containing proteins)	K02488	 Cell growth and death; Signal transduction	              Signal transduction	               02020 Two-component system	COG3706	TK
LFTS_00271	154.072239146973	-0.474639581825447	0.260319152246495	-1.82329873821967	0.0682581573218278	0.167346922191385	264	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00886	484.991878622987	-0.30535498509476	0.167552789833238	-1.82244047024626	0.0683881786234508	0.167500504490541	357	3-dehydroquinate synthase	NA	K01735	 Overview; Amino acid metabolism	              Overview	               01230 Biosynthesis of amino acids	COG0337	E
LFTS_01342	1991.69871716725	-0.259582566982228	0.143605463733529	-1.80760926662166	0.0706673349736174	0.172912396401981	1053	methylthioribose-1-phosphate isomerase	NA	K08963	 Amino acid metabolism	              Amino acid metabolism	               00270 Cysteine and methionine metabolism	NA	
LFTS_01278	96.6770137127487	0.431189550059034	0.238669256135508	1.80664052438417	0.0708183466422734	0.173111514014446	282	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01520	745.222876691453	-0.350268642194224	0.194143122438698	-1.80417744288018	0.0712034943466125	0.173524186276924	3084	cobalt-zinc-cadmium resistance protein CzcA	Cadmium/cobalt/zinc resistance	K15726	NA	              Signal transduction	               02020 Two-component system	COG3696	P
LFTS_02308	56.3785117843851	-0.544094169035158	0.301629416498348	-1.80384982125289	0.0712548531023231	0.173524186276924	951	PilZ domain-containing protein	c-di-GMP effector proteins; Cellulose production	K00694	 Carbohydrate metabolism; Cellular community - prokaryotes	              Carbohydrate metabolism	               00500 Starch and sucrose metabolism	COG1215	N
LFTS_01218	567.685168450512	-0.406226706785721	0.225249955224754	-1.80344855731664	0.0713177975698204	0.173524186276924	867	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00984	150.44063706481	0.413353107176016	0.22920869485896	1.8033919150858	0.0713266864511642	0.173524186276924	1236	Apolipoprotein N-acyltransferase	NA	K03820	NA	              Drug resistance	               01501 beta-Lactam resistance	COG0815	M
LFTS_02066	196.01038425301	-0.372965413629135	0.206820218909522	-1.80333149048786	0.0713361699014548	0.173524186276924	1728	DNA helicase/exodeoxyribonuclease V%2C alpha subunit	NA	K03581	 Replication and repair	              Replication and repair	               03440 Homologous recombination	COG0507	L
LFTS_00990	199.125967963014	-0.341013874903102	0.189652679255903	-1.79809679589584	0.0721616699127414	0.175350859091061	930	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00143	1008.98743361014	-0.239593793982728	0.133279659476631	-1.79767711685021	0.0722281897462777	0.175350859091061	1212	HD domain-containing protein	NA	K07814	NA	              Folding, sorting and degradation	               04122 Sulfur relay system	COG3437	T
LFTS_01718	584.011852454343	-0.262538787784558	0.146117957525369	-1.79675922269154	0.072373852528466	0.17553307062026	684	serine/threonine protein phosphatase 1	NA	K07313	NA	              Metabolism of terpenoids and polyketides	               00900 Terpenoid backbone biosynthesis	COG0639	T
LFTS_01048	68.4293691974712	0.480604705347292	0.267734330423392	1.7950806106459	0.0726408575065422	0.175993284573867	462	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00760	709.936238423498	-0.2484413288223	0.138432342054406	-1.79467691679057	0.0727051903690111	0.175993284573867	1440	metallo-beta-lactamase family protein	NA	K07576	NA	              Energy metabolism	               00190 Oxidative phosphorylation	COG1236	J
LFTS_00476	421.400285267968	-0.279151039129565	0.155781507276793	-1.791939518428	0.0731426548005533	0.176879999838692	678	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_02413	897.054438080503	0.350323237630083	0.196049083995635	1.78691596252437	0.0739510721549521	0.178661190842771	693	phospholipase/carboxylesterase	NA	K06130	 Lipid metabolism	              Lipid metabolism	               00564 Glycerophospholipid metabolism	NA	
LFTS_02397	5191.03278744199	0.213767209247115	0.12000345940696	1.78134205716671	0.0748565877866156	0.180673278871385	255	4Fe-4S dicluster domain-containing protein	NA	K14120	NA	              Translation	               03010 Ribosome	COG1145	C
LFTS_01970	497.46523814094	-0.370095319753337	0.207986617936119	-1.7794189040903	0.0751711094636526	0.181256428832823	207	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00530	158.349693427764	-0.398025552897343	0.223868619437448	-1.77794258926298	0.075413284444108	0.181611761816602	1056	Glycosyltransferase involved in cell wall bisynthesis	Extracellular polysaccharide production and export	K07011	NA	              Metabolism of terpenoids and polyketides	               00523 Polyketide sugar unit biosynthesis	COG1216	G
LFTS_01505	22553.2232327401	-0.450522245583008	0.253439776867518	-1.77763037496088	0.0754645816398027	0.181611761816602	207	cold shock protein (beta-ribbon%2C CspA family)	NA	K03704	NA	              Membrane transport	               03070 Bacterial secretion system	COG1278	K
LFTS_00821	806.478865125402	-0.295778202023576	0.166468371244718	-1.77678317996375	0.0756039203364864	0.18177112761751	930	menaquinol-cytochrome c reductase iron-sulfur subunit	Cytochrome b/c1	K03886	 Energy metabolism	              Energy metabolism	               00190 Oxidative phosphorylation	COG0723	C
LFTS_01383	104.285005364753	-0.443002540467977	0.249633329766767	-1.77461295285319	0.0759618170226697	0.182455146974258	1119	ABC-2 type transport system permease protein	NA	K09686	NA	NA	NA	NA	
LFTS_00802	1466.24281929058	0.276106671740136	0.155942647116905	1.77056550497791	0.076632982439519	0.183828633894643	504	ribosome maturation factor RimP	NA	K09748	NA	              Translation	               03010 Ribosome	COG0779	J
LFTS_02148	593.023357479203	0.268159459586808	0.151479084012156	1.77027383902908	0.0766815339295029	0.183828633894643	1035	Methyltransferase domain-containing protein	NA	K00598	NA	              Overview	               01200 Carbon metabolism	COG0500	QR
LFTS_00557	129.029792439121	-0.392381893122255	0.22175547524032	-1.76943497199798	0.0768213137690913	0.183986306387246	582	RNA polymerase sigma-70 factor%2C ECF subfamily	NA	K03088	NA	              Cellular community - prokaryotes	               02026 Biofilm formation - Escherichia coli	COG1595	K
LFTS_00171	354.234208675129	0.295539171753001	0.167361053814084	1.76587781337292	0.077416350164444	0.18509893879238	855	Tetratricopeptide repeat-containing protein	NA	K09527	NA	              Metabolism of cofactors and vitamins	               00130 Ubiquinone and other terpenoid-quinone biosynthesis	NA	
LFTS_01199	43.9926837163316	-0.557605892878485	0.315786626340371	-1.76576791531846	0.0774347933805611	0.18509893879238	984	cyclic pyranopterin phosphate synthase	NA	K03639	 Metabolism of cofactors and vitamins; Folding, sorting and degradation	              Metabolism of cofactors and vitamins	               00790 Folate biosynthesis	COG2896	H
LFTS_02429	1202.08833388607	0.242798650772324	0.137671471838371	1.76360902901783	0.0777978265195813	0.185702277963136	1260	glucose-1-phosphate adenylyltransferase	NA	K00975	 Carbohydrate metabolism; Cellular community - prokaryotes	              Carbohydrate metabolism	               00500 Starch and sucrose metabolism	COG0448	G
LFTS_00823	476.938807364882	0.288424801779891	0.163604238307958	1.76294211423165	0.0779102531232165	0.185702277963136	252	Glutaredoxin	Oxidative stress response	K03671	 Cardiovascular diseases; Immune system	              Immune system	               04621 NOD-like receptor signaling pathway	COG0526	O
LFTS_01838	85.4370728088354	-0.463093837375624	0.262683303099974	-1.76293594572083	0.0779112936104386	0.185702277963136	441	4-carboxymuconolactone decarboxylase	NA	K01607	 Xenobiotics biodegradation and metabolism; Overview	              Overview	               01220 Degradation of aromatic compounds	COG0599	R
LFTS_00127	3698.15943163981	-0.309638623235294	0.175775268900112	-1.76155966179322	0.0781437243979417	0.186077872464831	483	hypothetical protein	NA	K04542	 Environmental adaptation; Nervous system; Signal transduction; Substance dependence; Cancers; Immune system	              Signal transduction	               04014 Ras signaling pathway	NA	
LFTS_00900	1749.28039940532	0.2365622629362	0.13436303614244	1.76062010600458	0.0783027232739977	0.186278057472879	825	tol-pal system protein YbgF	NA	K05807	NA	              Metabolism of cofactors and vitamins	               00860 Porphyrin and chlorophyll metabolism	COG4105	M
LFTS_01787	159.076132114286	0.468760248978471	0.26632931398471	1.76007755948856	0.0783946570500354	0.186318467902857	240	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01597	1715.60304448738	-0.292605591179035	0.166479168247109	-1.75761084260533	0.078813747205408	0.187135602247034	1806	PAS domain S-box-containing protein	NA	K00936	NA	              Cellular community - prokaryotes	               02024 Quorum sensing	NA	
LFTS_01357	1102.02277091467	0.225801239440901	0.128665317322666	1.75495031714442	0.0792678063429616	0.188034128405155	1239	aspartate kinase	NA	K00928	 Amino acid metabolism; Overview; Biosynthesis of other secondary metabolites	              Overview	               01210 2-Oxocarboxylic acid metabolism	COG0527	E
LFTS_01613	266.254235388623	0.31166433171084	0.17779269938835	1.75296473242738	0.0796080609585059	0.188437836943544	858	ABC-2 type transport system permease protein	NA	K09686	NA	NA	NA	NA	
LFTS_00937	1996.59783162605	-0.21569175540477	0.123073101675965	-1.75254992738103	0.0796792926749892	0.188437836943544	909	FdhE protein	NA	K02380	NA	              Replication and repair	               03410 Base excision repair	COG3058	CO
LFTS_02478	4831.92493186516	-0.23478697502746	0.133990408666145	-1.75226702690685	0.0797279030056478	0.188437836943544	948	TPR repeat-containing protein	NA	K03350	 Cell growth and death; Endocrine system; Folding, sorting and degradation; Infectious diseases	              Folding, sorting and degradation	               04120 Ubiquitin mediated proteolysis	NA	
LFTS_00130	936.316549582981	0.247192585425417	0.141076382332111	1.75218970985161	0.0797411924636396	0.188437836943544	1215	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_02411	199.852989571665	0.362095949692309	0.207339659206735	1.74639020377317	0.0807431710312707	0.190624428474586	534	peptide deformylase	NA	K01462	NA	              Metabolism of cofactors and vitamins	               00670 One carbon pool by folate	COG0242	J
LFTS_01007	273.86230902081	0.326567680924962	0.187461720663447	1.74204994902002	0.0814997044722976	0.192227955709803	543	hypothetical protein	NA	K07038	NA	              Cellular community - prokaryotes	               02024 Quorum sensing	COG1988	R
LFTS_01645	976.471903630316	0.277558283646416	0.159853377575401	1.73633042889879	0.08250542583463	0.194253445789448	288	ribosomal protein L15	NA	K02876	 Translation	              Translation	               03010 Ribosome	COG0200	J
LFTS_00621	7831.27759144087	0.312415945557297	0.179934315341857	1.73627773537103	0.082514738034456	0.194253445789448	909	4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NA	K03527	 Metabolism of terpenoids and polyketides	              Metabolism of terpenoids and polyketides	               00900 Terpenoid backbone biosynthesis	COG0761	I
LFTS_01551	7505.58853612433	-0.21712256179547	0.125326329099806	-1.73245768351326	0.0831921052009852	0.195335824539328	4578	glutamate synthase (NADPH/NADH) large chain	NA	K00265	 Energy metabolism; Amino acid metabolism; Overview	              Overview	               01230 Biosynthesis of amino acids	COG0067;COG0069;COG0070	E
LFTS_00620	5918.87786928212	0.187118897804707	0.108027993964505	1.73213341225412	0.0832498114291755	0.195335824539328	1011	dihydroflavonol-4-reductase	NA	K00091	NA	              Signal transduction	               02020 Two-component system	COG0451	M
LFTS_02267	425.015961428781	0.315643100298541	0.182240542191359	1.73201361509946	0.0832711383306278	0.195335824539328	633	imidazoleglycerol-phosphate dehydratase	NA	K01693	 Overview; Amino acid metabolism	              Overview	               01230 Biosynthesis of amino acids	COG0131	E
LFTS_00769	1395.77769418707	0.240821527174639	0.1390493254738	1.73191438616518	0.0832888069234465	0.195335824539328	1404	phosphomannomutase / phosphoglucomutase	Extracellular polysaccharide production and export	K15778	 Carbohydrate metabolism; Biosynthesis of other secondary metabolites; Nucleotide metabolism	              Carbohydrate metabolism	               00010 Glycolysis / Gluconeogenesis	COG1109	G
LFTS_00806	405.559801639624	0.305997232749717	0.176874763560659	1.73002200308116	0.0836263441160812	0.195942593282354	396	ribosome-binding factor A	NA	K02834	NA	              Translation	               03010 Ribosome	COG0858	J
LFTS_00408	1614.24405346677	0.28552584594089	0.165280593082667	1.7275219105614	0.0840739736441363	0.19680593077149	1218	Transposase (or an inactivated derivative)	NA	K07493	NA	              Lipid metabolism	               00564 Glycerophospholipid metabolism	COG3328	X
LFTS_01322	340.174375273161	-0.348615144841285	0.202346649645307	-1.72286096879969	0.084913670118056	0.198584556833008	888	NTE family protein	NA	K07001	NA	              Glycan biosynthesis and metabolism	               00540 Lipopolysaccharide biosynthesis	COG1752	R
LFTS_02357	907.215888416808	0.228856594731897	0.133014073904772	1.72054421019945	0.085333564629272	0.199378986530423	930	ornithine carbamoyltransferase	NA	K00611	 Overview; Amino acid metabolism	              Overview	               01230 Biosynthesis of amino acids	COG0078	E
LFTS_01457	211.789885642735	-0.357105746555085	0.207734113740867	-1.71905201377059	0.0856049013286484	0.199825149955887	423	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00057	140.854708066516	0.378369462550124	0.220355677173078	1.71708515707056	0.0859636137789841	0.200474243765998	975	peptide/nickel transport system permease protein	NA	K02033	 Cellular community - prokaryotes	              Cellular community - prokaryotes	               02024 Quorum sensing	COG0601	EP
LFTS_00910	21.1714041065203	-0.683229285959271	0.39833537357163	-1.71521117954746	0.0863065159301289	0.201085284538239	303	hypothetical protein	NA	K07733	NA	              Membrane transport	               02010 ABC transporters	COG3311	KX
LFTS_00088	420.35243246221	-0.28939586162225	0.169029695718977	-1.71210070746024	0.0868781110291556	0.202227513125918	852	hydroxymethylpyrimidine/phosphomethylpyrimidine kinase	NA	K14153	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00730 Thiamine metabolism	COG0351;COG0352	H
LFTS_02209	463.348201996636	-0.26730172953249	0.156365350683679	-1.70946906308694	0.0873640975595628	0.203168518740012	471	putative nucleic acid-binding protein%2C contains PIN domain	NA	K07064	NA	              Overview	               01220 Degradation of aromatic compounds	COG1848	R
LFTS_01634	703.432427905957	0.313071332757828	0.183284904092211	1.70811302932139	0.087615371752166	0.203562443155032	858	trehalose 6-phosphate phosphatase	Lipopolysaccharide synthesis	K01087	 Carbohydrate metabolism	              Carbohydrate metabolism	               00500 Starch and sucrose metabolism	COG1877	G
LFTS_01980	2213.11077339497	-0.254475025722322	0.149170262201266	-1.70593670592987	0.0880198646951532	0.204205561854052	1437	proteasome accessory factor A	NA	K13571	NA	              Folding, sorting and degradation	               03050 Proteasome	NA	
LFTS_01118	100.551617357348	0.444215789284969	0.260424060381567	1.70574020170838	0.0880564611052068	0.204205561854052	1239	Type II secretory pathway%2C component PulF	NA	K02653	NA	              Replication and repair	               03030 DNA replication	COG1459	NUW
LFTS_01905	403.888143605049	0.260243057811617	0.152724890828621	1.70399897750554	0.088381278265107	0.204767807797815	1122	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_02364	869.369772889945	-0.280994081172695	0.16500847852495	-1.70290692747771	0.0885854874183196	0.205049834005533	513	chorismate lyase	NA	NA	NA	NA	NA	NA	NA
LFTS_01254	46.3330871811319	-0.514168316136859	0.3024158633729	-1.70020286106107	0.0890927743049525	0.205867002495198	165	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00938	678.792743340878	-0.237717000677736	0.139821816575859	-1.70014241338915	0.089104141063891	0.205867002495198	252	hypothetical protein	NA	K06575	 Immune system; Infectious diseases	              Immune system	               04640 Hematopoietic cell lineage	NA	
LFTS_01224	218.541220056593	0.379542617523539	0.223390647544191	1.69900853816388	0.0893175748815789	0.206045641068135	1125	histidinol-phosphate aminotransferase	NA	K00817	 Overview; Amino acid metabolism; Biosynthesis of other secondary metabolites	              Overview	               01230 Biosynthesis of amino acids	COG0079	E
LFTS_01506	302.336661990634	-0.350298221540255	0.206197118830257	-1.69885119407815	0.0893472248879525	0.206045641068135	603	general secretion pathway protein H	NA	K02457	 Cellular community - prokaryotes; Membrane transport	              Membrane transport	               03070 Bacterial secretion system	COG2165	NUW
LFTS_02365	3068.270429117	-0.216791757879603	0.127827308050699	-1.69597374133561	0.089890853041005	0.207107192455921	1593	hypothetical protein	NA	K04034	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00860 Porphyrin and chlorophyll metabolism	COG1032	R
LFTS_02489	1101.03235825532	-0.272932638128115	0.161151911798872	-1.69363574456847	0.0903345213692054	0.20786076275516	486	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01595	2563.22038421939	-0.214758318455979	0.126900399447794	-1.69233760800201	0.0905816210793748	0.20786076275516	2625	PAS domain S-box-containing protein/diguanylate cyclase (GGDEF) domain-containing protein	Genes encoding proteins with EAL and GGDEF domains	K14051	 Cellular community - prokaryotes	              Cellular community - prokaryotes	               02024 Quorum sensing	COG2199;COG2200;COG2202	T
LFTS_01995	407.728548349613	-0.289307221766794	0.170972025971751	-1.69213191527949	0.0906208244537203	0.20786076275516	960	riboflavin kinase / FMN adenylyltransferase	NA	K11753	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00740 Riboflavin metabolism	COG0196	H
LFTS_01183	10.7111077911727	0.720601333878736	0.426013523998011	1.69149872782466	0.0907415905580488	0.20786076275516	357	nitrogenase-stabilizing/protective protein	Nitrogenase genes	K02595	NA	              Signal transduction	               02020 Two-component system	NA	
LFTS_00737	55.1729547609105	-0.571474555104093	0.337867234859243	-1.69141750410386	0.0907570914985786	0.20786076275516	2892	Tetratricopeptide repeat protein	NA	K05838	NA	              Energy metabolism	               00190 Oxidative phosphorylation	COG3118	O
LFTS_01734	224.788824400021	0.34844109726415	0.206013105577182	1.69135403443354	0.0907692056934691	0.20786076275516	1002	Cache domain-containing protein	NA	K10937	 Cellular community - prokaryotes	              Cellular community - prokaryotes	               05111 Biofilm formation - Vibrio cholerae	NA	
LFTS_00783	658.178190803711	0.279547463458578	0.165297686801636	1.69117589524436	0.0908032133355204	0.20786076275516	714	Vitamin B12 dependent methionine synthase%2C activation domain	NA	K00548	 Amino acid metabolism; Overview; Metabolism of cofactors and vitamins; Metabolism of other amino acids	              Overview	               01230 Biosynthesis of amino acids	COG0646;COG1410	E
LFTS_02248	1897.60673807923	0.220382405503517	0.130539228653644	1.688246573666	0.0913639062772275	0.208809798217387	1932	ATP-binding cassette%2C subfamily F%2C member 3	NA	K06158	NA	              Folding, sorting and degradation	               04141 Protein processing in endoplasmic reticulum	COG0488	R
LFTS_01510	770.081957156817	-0.253371735825628	0.150089952146376	-1.68813256452055	0.0913857845778429	0.208809798217387	1314	ATP phosphoribosyltransferase regulatory subunit	NA	K02502	 Overview; Amino acid metabolism	              Overview	               01230 Biosynthesis of amino acids	COG3705	E
LFTS_01432	196.153813526601	-0.369972643514057	0.219671998917564	-1.68420483874641	0.0921420884486093	0.210344565549351	462	Transposase	NA	K07488	NA	              Nucleotide metabolism	               00230 Purine metabolism	COG3676	X
LFTS_00453	430.403069827633	0.390578357960236	0.232111078422547	1.6827217408779	0.092428970977489	0.210805891605539	1704	K+-transporting ATPase ATPase A chain	Role of potassium in the internal positive membrane potential	K01546	 Signal transduction	              Signal transduction	               02020 Two-component system	COG2060	P
LFTS_01789	25.7202083404947	0.614332119632508	0.365561824376472	1.68051497357624	0.0928571634654762	0.211588366979994	762	DNA replication protein DnaC	NA	K02315	NA	              Metabolism of cofactors and vitamins	               00860 Porphyrin and chlorophyll metabolism	COG1484	L
LFTS_01828	981.427208947936	-0.331779974356584	0.197524469832354	-1.67969049423688	0.0930175502311945	0.211759734317536	1668	NAD(P)H-quinone oxidoreductase subunit 5	NADH dehydrogenase	K05577	 Energy metabolism	              Energy metabolism	               00190 Oxidative phosphorylation	COG1009	CP
LFTS_02190	520.384389466953	-0.301678415157821	0.179694886276822	-1.6788369519491	0.0931838248021892	0.211944179742216	627	chromosome partitioning protein	NA	K03496	NA	              Carbohydrate metabolism	               00630 Glyoxylate and dicarboxylate metabolism	COG1192	N
LFTS_00431	11.5255573645472	0.707798168444555	0.421763609512398	1.67818690963604	0.0933106164265935	0.21203856712661	195	helix-turn-helix protein	NA	K07108	NA	              Overview	               01210 2-Oxocarboxylic acid metabolism	COG2522	R
LFTS_01298	385.440989183686	0.380403433596742	0.226750007774514	1.6776336077352	0.0934186477306806	0.212065874356448	1074	Glycosyl transferase family 2	Lipopolysaccharide synthesis	K07011	NA	              Membrane transport	               02010 ABC transporters	COG1216	G
LFTS_01618	1450.45977008974	0.211536080033641	0.126120641053733	1.67725186191781	0.0934932414700995	0.212065874356448	933	LysR family transcriptional regulator%2C nitrogen assimilation regulatory protein	Nitrate/nitrite regulation	K11921	NA	              Nucleotide metabolism	               00230 Purine metabolism	COG0583	K
LFTS_01332	1368.19378720713	0.261207685921553	0.156208668377197	1.67217151669723	0.0944905054030129	0.214132540047302	1569	phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase	NA	K00602	 Metabolism of cofactors and vitamins; Nucleotide metabolism; Drug resistance	              Nucleotide metabolism	               00230 Purine metabolism	COG0138	F
LFTS_01327	130.334635536363	-0.358053624951031	0.214732972255437	-1.6674366362568	0.0954276140673797	0.216059242779149	552	undecaprenyl-diphosphatase	NA	K01096	 Lipid metabolism	              Lipid metabolism	               00564 Glycerophospholipid metabolism	COG0671	I
LFTS_02384	347.472802442741	0.288769748555317	0.173246288572169	1.66681636262023	0.0955509256104184	0.216141584228845	774	phospholipid/cholesterol/gamma-HCH transport system ATP-binding protein	NA	K02065	 Membrane transport	              Membrane transport	               02010 ABC transporters	COG1127	M
LFTS_01738	73.1644837560829	-0.457068524887696	0.274514937789578	-1.66500420184074	0.0959119175280008	0.216760933613282	495	methylated-DNA-[protein]-cysteine S-methyltransferase	NA	K00567	NA	              Carbohydrate metabolism	               00500 Starch and sucrose metabolism	COG0350	L
LFTS_01972	14215.488498305	0.215685260502768	0.129756145503984	1.66223541601846	0.0964655814974755	0.217814201274046	531	cytochrome c oxidase cbb3-type subunit 2	Cytochrome cbb3 oxidase	K00405	 Energy metabolism; Signal transduction	              Energy metabolism	               00190 Oxidative phosphorylation	COG2993	C
LFTS_00044	1090.58974561413	0.229701404179916	0.138340495604388	1.66040611012984	0.0968327817813747	0.218392305418447	732	outer membrane protein assembly factor BamD	NA	K05807	NA	              Metabolism of cofactors and vitamins	               00860 Porphyrin and chlorophyll metabolism	COG4105	M
LFTS_01238	137.792005187513	-0.394201935523012	0.237458855187908	-1.66008521859953	0.0968973100871066	0.218392305418447	177	hypothetical protein	NA	K15152	NA	              Biosynthesis of other secondary metabolites	               00405 Phenazine biosynthesis	NA	
LFTS_00582	1034.07509619871	0.305786691151712	0.184316634988889	1.65902926325747	0.0971098956985362	0.218555946471908	810	citryl-CoA lyase	Reductive TCA cycle carbon dioxide fixation	K15234	 Overview; Energy metabolism	              Overview	               01200 Carbon metabolism	NA	
LFTS_01758	104.694528293895	0.439938751503209	0.265206851892525	1.65885137719403	0.0971457445098383	0.218555946471908	306	putative ATP-dependent DNA helicase MPH1	NA	K04560	 Substance dependence; Folding, sorting and degradation; Nervous system; Endocrine system	              Folding, sorting and degradation	               04130 SNARE interactions in vesicular transport	NA	
LFTS_02206	1216.75367584972	-0.242134686638748	0.146040974824265	-1.65799144336112	0.097319193467173	0.218748205207407	906	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01523	681.661803332727	0.23983895547891	0.14481268521935	1.65620128592756	0.0976810629297973	0.219243225812546	1194	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01884	926.680075372002	-0.225646464598806	0.136257499378528	-1.65602969104807	0.0977158061948115	0.219243225812546	2055	Glucoamylase (glucan-1%2C4-alpha-glucosidase)%2C GH15 family	NA	K01178	 Carbohydrate metabolism	              Carbohydrate metabolism	               00500 Starch and sucrose metabolism	COG3387	G
LFTS_02523	323.545155287394	0.293394817303588	0.177571455542863	1.65226340239558	0.0984808664745371	0.220760535667898	852	hypothetical protein	NA	K09719	NA	              Membrane transport	               02010 ABC transporters	COG1689	S
LFTS_00624	85.6328406794274	0.42960491770687	0.260198139918351	1.65106836598324	0.0987246158598703	0.221107563087962	294	EamA-like transporter family protein	NA	K12962	 Drug resistance	              Drug resistance	               01503 Cationic antimicrobial peptide (CAMP) resistance	COG0697	GER
LFTS_02006	168.227693332478	-0.32438986152247	0.196724033191072	-1.64895898208533	0.0991560382340721	0.221873907335647	1695	monovalent cation:H+ antiporter%2C CPA1 family	Proton transporters	K03316	NA	              Membrane transport	               02060 Phosphotransferase system (PTS)	COG0025	P
LFTS_01180	4.0389673955165	-0.683679490502189	0.414894863962902	-1.64783792205082	0.0993859349127715	0.222188340101754	261	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01946	555.739875238121	0.253937215267488	0.154246630513004	1.64630640178606	0.0997006921353302	0.222691752604161	801	Zinc carboxypeptidase	NA	K06987	NA	              Energy metabolism	               00190 Oxidative phosphorylation	COG3608	R
LFTS_01215	856.680084511903	-0.318872911121982	0.193883541176727	-1.64466209553768	0.100039513653672	0.223247963144549	1980	PAS domain S-box-containing protein	Quorum sensing	K07710	 Signal transduction	              Signal transduction	               02020 Two-component system	COG0642	T
LFTS_02034	92.3366323881226	0.40352879264537	0.246289930142435	1.63842992854803	0.101332040164907	0.225929553228662	3456	conjugative relaxase domain-containing protein%2C TrwC/TraI family	NA	K03581	 Replication and repair	              Replication and repair	               03440 Homologous recombination	COG0507	L
LFTS_01632	1846.06920014139	0.247047082301008	0.151114812145773	1.63483035708435	0.102084615060627	0.227131268313594	1086	Glycosyltransferase involved in cell wall bisynthesis	Lipopolysaccharide synthesis	K03867	NA	              Carbohydrate metabolism	               00500 Starch and sucrose metabolism	COG0438	M
LFTS_01997	598.24625487431	0.255360796890859	0.156231151116208	1.63450627526207	0.10215258968228	0.227131268313594	531	hypoxanthine phosphoribosyltransferase	NA	K00760	 Xenobiotics biodegradation and metabolism; Nucleotide metabolism	              Nucleotide metabolism	               00230 Purine metabolism	COG0634	F
LFTS_01890	274.963557721671	0.277846669559101	0.170021529565004	1.63418521330778	0.10221996641572	0.227131268313594	444	HSP20 family protein	NA	K13993	 Folding, sorting and degradation	              Folding, sorting and degradation	               04141 Protein processing in endoplasmic reticulum	COG0071	O
LFTS_01331	384.33229565366	0.261637241459178	0.160110270427125	1.63410654895036	0.102236479985081	0.227131268313594	1515	Dolichyl-phosphate-mannose-protein mannosyltransferase	Lipopolysaccharide synthesis	K07264	 Drug resistance	              Drug resistance	               01503 Cationic antimicrobial peptide (CAMP) resistance	COG1807	M
LFTS_00815	404.155445936321	0.259844058369708	0.159230648752352	1.63187213269374	0.102706425701312	0.227971584190591	792	DNA polymerase	NA	K02334	NA	              Folding, sorting and degradation	               03018 RNA degradation	COG1573	L
LFTS_01627	1671.07844041737	-0.201423763091621	0.123474899255498	-1.6312931964806	0.102828468278733	0.228038868992801	1515	amidophosphoribosyltransferase	NA	K00764	 Amino acid metabolism; Nucleotide metabolism	              Nucleotide metabolism	               00230 Purine metabolism	COG0034	F
LFTS_01406	890.419788083701	0.218774175621257	0.134160893422087	1.63068514259939	0.10295677316246	0.228119909163882	3528	putative protein YhaN	NA	K03546	NA	              Transport and catabolism	               04144 Endocytosis	COG0419	L
LFTS_01132	125.089478308084	0.366217164975198	0.224656847543788	1.63011797316269	0.103076565789377	0.228127982488163	1980	type IV secretion system protein VirD4	NA	K03205	 Membrane transport	              Membrane transport	               03070 Bacterial secretion system	COG3505	U
LFTS_01028	1439.3456317956	0.233988669947447	0.143569019254816	1.6297991806446	0.103143947030046	0.228127982488163	1167	transposase%2C IS605 OrfB family%2C central region	NA	K07496	NA	              Metabolism of other amino acids	               00410 beta-Alanine metabolism	COG0675	X
LFTS_01572	146.326966164197	0.34602494185891	0.212632931664848	1.62733467083224	0.10366603816324	0.22907890744339	204	zinc-binding protein	NA	K09862	NA	              Metabolism of cofactors and vitamins	               00780 Biotin metabolism	COG3024	L
LFTS_00261	156.966670197409	-0.348789766046246	0.214415278970684	-1.62670201359081	0.103800400898824	0.229172110687812	474	dUTP pyrophosphatase	NA	K01520	 Nucleotide metabolism	              Nucleotide metabolism	               00240 Pyrimidine metabolism	COG0756	FV
LFTS_02181	792.420669401076	0.266096623517453	0.163656330326863	1.62594763664803	0.10396079511486	0.229322570235618	744	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00264	329.886513690536	0.283431273137858	0.174421507586177	1.62497892066334	0.104167050419408	0.229522528418325	822	putative amidohydrolase	NA	K08590	 Amino acid metabolism	              Amino acid metabolism	               00250 Alanine, aspartate and glutamate metabolism	COG0388	R
LFTS_00800	686.528142025084	0.263823023871524	0.162408437776953	1.62444160834704	0.104281592980364	0.229522528418325	603	hypothetical protein	NA	K16211	NA	              Translation	               03010 Ribosome	COG0477	GEPR
LFTS_02160	2751.32673430174	0.246052861421407	0.15148966744664	1.62422207117245	0.104328422008329	0.229522528418325	756	3-oxoacyl-[acyl-carrier-protein] reductase	NA	K00059	 Lipid metabolism; Overview; Metabolism of cofactors and vitamins	              Overview	               01212 Fatty acid metabolism	COG1028	IQR
LFTS_02288	616.478202917894	0.362981957599838	0.223819887389049	1.62175918250238	0.104854921290994	0.230476865012742	1023	phosphate ABC transporter membrane protein 1%2C PhoT family	NA	K02037	 Membrane transport	              Membrane transport	               02010 ABC transporters	COG0573	P
LFTS_00893	102.441832388472	0.396297079306742	0.244474637983075	1.62101509823763	0.105014400704178	0.230623498366243	522	DDE superfamily endonuclease	NA	NA	NA	NA	NA	NA	NA
LFTS_02469	915.73018537877	-0.21473424329648	0.132541734631474	-1.6201254940079	0.10520532201096	0.230838861888126	1269	anhydro-N-acetylmuramic acid kinase	NA	K09001	NA	              Nucleotide metabolism	               00230 Purine metabolism	COG2377	M
LFTS_01394	869.657767084502	0.247458579379476	0.152842944527156	1.61903828891172	0.105439025115553	0.231147633542561	1644	phosphoglucomutase	Extracellular polysaccharide production and export	K01835	 Carbohydrate metabolism; Nucleotide metabolism; Biosynthesis of other secondary metabolites	              Carbohydrate metabolism	               00010 Glycolysis / Gluconeogenesis	COG0033	G
LFTS_02014	221.956032307176	-0.333972348580646	0.206379375767793	-1.61824478506231	0.105609854766786	0.231318148854828	1584	deoxyribodipyrimidine photo-lyase	NA	K01669	NA	              Metabolism of cofactors and vitamins	               00790 Folate biosynthesis	COG0415	L
LFTS_02432	2186.52467175501	-0.195881365931369	0.121085254116489	-1.61771445549367	0.105724149247444	0.231364643511571	663	putative O-methyltransferase YrrM	NA	K00588	 Biosynthesis of other secondary metabolites; Amino acid metabolism	              Amino acid metabolism	               00360 Phenylalanine metabolism	COG4122	R
LFTS_01376	217.205485892813	-0.334426141262888	0.207117657456437	-1.61466745698989	0.106382728558144	0.232554905326607	927	beta-aspartyl-peptidase (threonine type)	NA	K13051	NA	              Folding, sorting and degradation	               04130 SNARE interactions in vesicular transport	COG1446	E
LFTS_02004	36.4977460136933	0.530657209826739	0.328716006778175	1.6143333421084	0.106455141698181	0.232554905326607	567	Nicotinamidase-related amidase	NA	K09020	 Nucleotide metabolism	              Nucleotide metabolism	               00240 Pyrimidine metabolism	COG1335	HR
LFTS_00531	185.78242292322	-0.370230860733315	0.229787090079811	-1.61119086631335	0.107138127957818	0.23384142765859	1104	Glycosyltransferase involved in cell wall bisynthesis	Extracellular polysaccharide production and export	K07011	NA	              Metabolism of terpenoids and polyketides	               00523 Polyketide sugar unit biosynthesis	COG1216	G
LFTS_00623	1257.93280588854	-0.206511310089989	0.128232662745141	-1.61044234494628	0.10730132255983	0.233992182354156	1239	ceramide glucosyltransferase	NA	K00720	 Lipid metabolism	              Lipid metabolism	               00600 Sphingolipid metabolism	COG1215	N
LFTS_00392	290.642761777876	0.291542983578599	0.181157534219508	1.60933402430471	0.107543323100048	0.234314374431831	1221	sodium/proton antiporter%2C CPA1 family	Proton transporters	K03316	NA	              Carbohydrate metabolism	               00520 Amino sugar and nucleotide sugar metabolism	COG0025	P
LFTS_00539	105.196349871597	0.388031034033763	0.24126511054479	1.60831805791383	0.10776553771483	0.234462699665583	837	putative PEP-CTERM system histidine kinase	Extracellular polysaccharide production and export	NA	NA	NA	NA	NA	NA
LFTS_01041	145.198527683019	0.364823418293176	0.226881640564018	1.60799004003251	0.107837360161506	0.234462699665583	2193	ribonucleoside-diphosphate reductase class II	NA	K00525	 Nucleotide metabolism	              Nucleotide metabolism	               00230 Purine metabolism	COG0209	F
LFTS_02191	235.635882333597	-0.36921679199068	0.229651003078792	-1.6077299338597	0.107894339669118	0.234462699665583	270	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01464	8.81760355847044	-0.694338849883897	0.432719451667264	-1.60459357028813	0.10858327734946	0.235607593248804	294	hypothetical protein	NA	K12068	NA	              Membrane transport	               03070 Bacterial secretion system	NA	
LFTS_02015	325.175924707594	-0.287598142101554	0.179248190745112	-1.60446887026332	0.108610740894259	0.235607593248804	1266	voltage-gated potassium channel	Role of potassium in the internal positive membrane potential; Proton transporters	K10716	NA	              Metabolism of cofactors and vitamins	               00790 Folate biosynthesis	COG1226	P
LFTS_01454	1243.66747533154	0.243661102181193	0.151910163488823	1.60398156769228	0.10871811559704	0.235634904423926	819	Prolipoprotein diacylglyceryl transferase	NA	K13292	NA	              Signal transduction	               02020 Two-component system	COG0682	M
LFTS_02457	8481.37188366572	0.3296302158395	0.20559584212296	1.60329222826578	0.108870151517895	0.235741109128688	867	pyruvate ferredoxin oxidoreductase beta subunit	Reductive TCA cycle carbon dioxide fixation	K00170	 Carbohydrate metabolism; Overview; Energy metabolism; Xenobiotics biodegradation and metabolism	              Overview	               01200 Carbon metabolism	COG1013	C
LFTS_01227	166.590353668556	-0.39433649886228	0.24602892420689	-1.60280544303269	0.108977614765257	0.235741109128688	846	Glyoxylase%2C beta-lactamase superfamily II	NA	K05555	 Metabolism of terpenoids and polyketides	              Metabolism of terpenoids and polyketides	               01057 Biosynthesis of type II polyketide products	COG0491	R
LFTS_02292	65.0940246787861	0.481578393629439	0.300522464841231	1.602470530394	0.109051599154461	0.235741109128688	780	two-component system%2C OmpR family%2C alkaline phosphatase synthesis response regulator PhoP	NA	K07658	 Signal transduction	              Signal transduction	               02020 Two-component system	COG0745	TK
LFTS_01671	909.636354931763	0.377894041337306	0.235963985731587	1.60149032983011	0.109268360133761	0.235848392905033	210	preprotein translocase subunit SecE	NA	K03073	 Cellular community - prokaryotes; Folding, sorting and degradation; Membrane transport	              Folding, sorting and degradation	               03060 Protein export	COG0690	U
LFTS_02527	194.984529466275	0.413867609775301	0.258499613117964	1.60103763709092	0.109368583274127	0.235848392905033	570	TPR repeat-containing protein	NA	K12284	NA	              Metabolism of cofactors and vitamins	               00860 Porphyrin and chlorophyll metabolism	NA	
LFTS_01990	3085.06581328564	-0.231391585818831	0.144570824663791	-1.60054137034181	0.109478536903808	0.235848392905033	810	ABC-type uncharacterized transport system%2C permease component	NA	K02497	NA	              Nucleotide metabolism	               00230 Purine metabolism	COG0755	O
LFTS_01745	97.7204758919378	-0.38577163478077	0.241032481875242	-1.60049646329595	0.109488490888592	0.235848392905033	1044	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01409	101.113032835818	0.389410898006188	0.243366038399742	1.60010369798007	0.109575580774462	0.235848392905033	717	Outer membrane protein OmpA	NA	K02557	 Cell motility	              Cell motility	               02030 Bacterial chemotaxis	COG1360	N
LFTS_01060	57.4323570821351	-0.454880218884767	0.284432091954914	-1.59925772003558	0.10976334983332	0.236048172738437	672	HD domain-containing protein	NA	K07814	NA	              Translation	               03010 Ribosome	COG3437	T
LFTS_01208	38.3086356591029	-0.513079892483192	0.321017574120333	-1.59829222399788	0.109977957166327	0.236227235694613	258	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00999	270.181100871553	-0.412543303728987	0.258157682624127	-1.59802838147429	0.110036660874643	0.236227235694613	156	hypothetical protein	NA	K12415	 Cellular community - prokaryotes; Signal transduction	              Signal transduction	               02020 Two-component system	NA	
LFTS_01308	764.30796306029	0.255462114915855	0.159926987793802	1.59736713884231	0.110183893003589	0.236339221748854	993	Glycosyltransferase%2C GT2 family	Lipopolysaccharide synthesis	K07011	NA	              Glycan biosynthesis and metabolism	               00540 Lipopolysaccharide biosynthesis	COG1216	G
LFTS_01035	1074.29220966867	0.23215583978249	0.145936643572265	1.59079881584046	0.111654859547205	0.238918655742143	2952	hypothetical protein	NA	K00558	 Amino acid metabolism; Cancers	              Amino acid metabolism	               00270 Cysteine and methionine metabolism	COG0270	L
LFTS_00695	1962.87445755068	0.245296571324797	0.154198527071134	1.59078414031567	0.111658163372608	0.238918655742143	561	NADH-quinone oxidoreductase subunit I	NADH dehydrogenase	K00338	 Energy metabolism	              Energy metabolism	               00190 Oxidative phosphorylation	COG1143	C
LFTS_01835	143.592385194705	-0.372195886356062	0.233980925200509	-1.59071037964787	0.11167476990039	0.238918655742143	834	Pimeloyl-ACP methyl ester carboxylesterase	NA	K06889	NA	              Amino acid metabolism	               00280 Valine, leucine and isoleucine degradation	COG1073	T
LFTS_01107	208.865643949113	0.305082915599691	0.192901861722703	1.58154469259736	0.113753548513274	0.243156768361133	1164	hypothetical protein	NA	K06871	NA	              Carbohydrate metabolism	               00520 Amino sugar and nucleotide sugar metabolism	COG0641	O
LFTS_01712	247.748064623945	0.678438913749383	0.430133990209301	1.57727342919182	0.114732623499769	0.245038919261534	456	hypothetical protein	NA	K07010	NA	              Signal transduction	               02020 Two-component system	COG2071	E
LFTS_00805	362.050451800723	-0.353681006088926	0.224388574574383	-1.57619881832122	0.114979990783557	0.245356443852295	300	hypothetical protein	NA	K09764	NA	              Translation	               03010 Ribosome	COG1550	S
LFTS_01439	536.418712466383	0.277518915042465	0.176411318768032	1.57313553903751	0.11568743738135	0.246581513270082	732	Zn-dependent protease (includes SpoIVFB)	NA	K06402	NA	              Metabolism of cofactors and vitamins	               00130 Ubiquinone and other terpenoid-quinone biosynthesis	COG1994	O
LFTS_00371	241.447504496911	0.335825116650625	0.213513120202845	1.57285470949785	0.11575246419396	0.246581513270082	492	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00691	4789.57776824399	0.195460546853822	0.124460979405687	1.57045644174716	0.116308960404182	0.247554859216435	507	NADH-quinone oxidoreductase subunit E	NADH dehydrogenase	K00334	 Energy metabolism	              Energy metabolism	               00190 Oxidative phosphorylation	COG1905	C
LFTS_02108	930.895385588142	-0.237851296295735	0.151718977117706	-1.56770959582206	0.116948921216142	0.248704036050751	669	putative membrane protein	NA	K10110	 Membrane transport	              Membrane transport	               02010 ABC transporters	COG3833	G
LFTS_01197	27.4668497743217	-0.584957685794645	0.373491036203052	-1.56618935688895	0.117304293615206	0.24924655891231	453	molybdopterin synthase catalytic subunit	NA	K03635	 Metabolism of cofactors and vitamins; Folding, sorting and degradation	              Metabolism of cofactors and vitamins	               00790 Folate biosynthesis	COG0314	H
LFTS_02515	1534.13160755178	-0.214610159794548	0.13707334510881	-1.56565931636226	0.117428395467684	0.249297174323367	555	peptide deformylase	NA	K01462	NA	              Metabolism of cofactors and vitamins	               00860 Porphyrin and chlorophyll metabolism	COG0242	J
LFTS_01977	597.167333326499	-0.311384467829444	0.199035824139156	-1.56446443335617	0.117708539242882	0.249678693308707	339	(2Fe-2S) ferredoxin	NA	K05587	 Energy metabolism	              Energy metabolism	               00190 Oxidative phosphorylation	COG1894	C
LFTS_01401	565.731752042197	-0.225476755042742	0.144347284020005	-1.56204362675431	0.118277711707136	0.250672115348628	288	hypothetical protein	NA	K06400	NA	              Transport and catabolism	               04144 Endocytosis	COG1961	L
LFTS_01413	133.876845357998	-0.360046267320381	0.231475958500255	-1.55543698642892	0.119842031087826	0.253623562054912	588	LPP20 lipoprotein	NA	NA	NA	NA	NA	NA	NA
LFTS_01626	959.766064173242	-0.233909572873833	0.150395039131747	-1.555301120464	0.1198743706414	0.253623562054912	2214	phosphoribosylformylglycinamidine synthase subunit II	NA	K01952	 Nucleotide metabolism	              Nucleotide metabolism	               00230 Purine metabolism	COG0046;COG0047	F
LFTS_00717	175.253575342789	-0.323547126751938	0.208289787516663	-1.55335088968802	0.120339328696731	0.254181851007389	1041	general secretion pathway protein K	NA	K02460	 Cellular community - prokaryotes; Membrane transport	              Membrane transport	               03070 Bacterial secretion system	COG3156	U
LFTS_01962	2921.2437857239	-0.189214133509226	0.121811415805303	-1.55333662496507	0.120342734768985	0.254181851007389	1329	Polyferredoxin	NA	K02574	NA	              Overview	               01200 Carbon metabolism	COG0348	C
LFTS_02371	151.160766200011	-0.341380666832588	0.220485055785906	-1.54831657690249	0.121546095266477	0.256505596631972	510	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00652	1560.05246356762	0.209249663004302	0.135395449186295	1.54547042948533	0.122232516126164	0.257735398718952	804	adenylyltransferase and sulfurtransferase	NA	K11996	 Folding, sorting and degradation	              Folding, sorting and degradation	               04122 Sulfur relay system	COG0476;COG0607	HP
LFTS_01442	1449.88948738736	0.222950951898938	0.144391027009194	1.54407761006327	0.122569532227044	0.25819521056103	3606	DNA polymerase-3 subunit alpha	NA	K02337	 Replication and repair; Nucleotide metabolism	              Nucleotide metabolism	               00230 Purine metabolism	COG0587	L
LFTS_00248	789.191006508302	0.280853970783218	0.181943062856737	1.54363659912862	0.122676393443395	0.25819521056103	414	hypothetical protein	NA	K02498	NA	              Translation	               03010 Ribosome	COG3071	S
LFTS_00011	499.415233833783	-0.262903476366813	0.170353397579972	-1.54328284672687	0.122762163669806	0.25819521056103	1737	HNH endonuclease	NA	K00568	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00130 Ubiquinone and other terpenoid-quinone biosynthesis	COG2227	H
LFTS_01195	17.8907404009593	-0.607030819280544	0.394042366575081	-1.5405217072385	0.123433235714704	0.259385316727834	507	cyclic pyranopterin phosphate synthase	NA	K03637	 Metabolism of cofactors and vitamins; Folding, sorting and degradation	              Metabolism of cofactors and vitamins	               00790 Folate biosynthesis	COG0315	H
LFTS_02082	732.580378819281	-0.208664780336471	0.135488069589865	-1.54009707989876	0.12353669147456	0.259385316727834	1374	phosphoglucosamine mutase	NA	K03431	 Carbohydrate metabolism	              Carbohydrate metabolism	               00520 Amino sugar and nucleotide sugar metabolism	COG1109	G
LFTS_00483	279.22745901289	0.269122449436314	0.17483181188065	1.53932197202207	0.123725712486826	0.259562971512446	648	hypothetical protein	NA	K14998	NA	              Overview	               01210 2-Oxocarboxylic acid metabolism	COG3346	O
LFTS_01934	368.714550974071	0.296531860991501	0.192744717817268	1.53846945508841	0.123933871391475	0.259780442056667	360	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_02500	217.021715863982	-0.321553763858833	0.209122997553285	-1.53762985238819	0.124139144047085	0.259991501348823	681	16S rRNA (guanine527-N7)-methyltransferase	NA	K03501	NA	              Folding, sorting and degradation	               03060 Protein export	COG0357	J
LFTS_02046	848.492056989417	0.215856877354467	0.140742651154489	1.53369909962494	0.125103695386217	0.261399499676941	462	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00833	837.331643013842	0.222853269340572	0.145306028399795	1.53368220021412	0.125107854840572	0.261399499676941	621	myosin	NA	NA	NA	NA	NA	NA	NA
LFTS_01148	154.622117911254	0.353657053365351	0.230605056222913	1.53360493979582	0.125126872331279	0.261399499676941	564	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01587	851.93140021443	0.266872492968971	0.174362869090656	1.53055805035083	0.125878656151732	0.262749235258779	405	DNA-directed RNA polymerase subunit omega	NA	K03060	 Nucleotide metabolism; Transcription	              Nucleotide metabolism	               00230 Purine metabolism	COG1758	K
LFTS_00829	2447.2439298645	-0.20869129534867	0.136393454280617	-1.53006826060221	0.125999833565162	0.262781532083048	1764	Tetratricopeptide repeat-containing protein	NA	K12600	 Folding, sorting and degradation	              Folding, sorting and degradation	               03018 RNA degradation	COG0457	R
LFTS_00692	10199.9053573533	0.239929021911114	0.157048927973858	1.52773422274523	0.126578539509302	0.26376718291712	1854	NAD(P)-dependent iron-only hydrogenase diaphorase component flavoprotein	NA	K05587	 Energy metabolism	              Energy metabolism	               00190 Oxidative phosphorylation	COG1894	C
LFTS_02257	5576.45491994489	0.234760674850298	0.154132934939498	1.52310520099062	0.12773238785708	0.26590106772301	1797	RNA polymerase%2C sigma 70 subunit%2C RpoD	NA	K03086	NA	              Replication and repair	               03030 DNA replication	COG0568	K
LFTS_02234	1014.6429793943	0.250863703634093	0.164768902136073	1.5225185115752	0.127879210634891	0.26590106772301	2145	glycogen operon protein	NA	K02438	 Carbohydrate metabolism	              Carbohydrate metabolism	               00500 Starch and sucrose metabolism	COG1523	G
LFTS_01865	240.863632532458	0.279019524766063	0.183283091865372	1.52234186976185	0.127923442074304	0.26590106772301	1080	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_02353	672.761194994206	-0.252332285222179	0.166189847702064	-1.51833754414738	0.128929327618163	0.267768010408314	498	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01981	1435.10128829866	0.219084987128041	0.144341421969435	1.51782478057084	0.129058576301758	0.267812705080275	756	proteasome alpha subunit	NA	K03432	 Folding, sorting and degradation	              Folding, sorting and degradation	               03050 Proteasome	COG0638	O
LFTS_02537	2014.23928543679	-0.186739285840531	0.123173537779456	-1.51606659358028	0.129502514404408	0.268509800508222	1599	2-isopropylmalate synthase	NA	K01649	 Amino acid metabolism; Overview; Carbohydrate metabolism	              Overview	               01210 2-Oxocarboxylic acid metabolism	COG0119	E
LFTS_00554	2.69002051047061	-0.583388768277668	0.385234954110387	-1.51437132599993	0.129931687544022	0.268855646201007	228	prevent-host-death family protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01878	303.673075623672	0.301096525820735	0.198846437125324	1.51421634791962	0.129970976734354	0.268855646201007	834	3-deoxy-manno-octulosonate cytidylyltransferase (CMP-KDO synthetase)	NA	K00979	 Glycan biosynthesis and metabolism	              Glycan biosynthesis and metabolism	               00540 Lipopolysaccharide biosynthesis	COG1212	M
LFTS_01831	557.899978387873	-0.275126482093561	0.181706404873983	-1.51412649589521	0.129993759748033	0.268855646201007	1470	two-component system%2C NtrC family%2C response regulator AtoC	NA	K07714	 Signal transduction	              Signal transduction	               02020 Two-component system	COG2204	T
LFTS_02044	84.2161396544184	-0.432567452801794	0.285945315043862	-1.51276286074294	0.13033990575418	0.269347469413874	357	Sugar phosphate permease	NA	K08153	NA	              Metabolism of cofactors and vitamins	               00860 Porphyrin and chlorophyll metabolism	COG0477	GEPR
LFTS_00319	1546.21518797356	-0.186368199463182	0.123303010787902	-1.51146511567152	0.130669989982055	0.269805311541021	2592	puromycin-sensitive aminopeptidase	NA	K08776	NA	              Cell growth and death	               04214 Apoptosis - fly	NA	
LFTS_01491	536.477014435538	0.218097550053773	0.144385620135449	1.51052126831726	0.130910466617263	0.270077526979682	879	hypothetical protein	NA	K02656	NA	              Overview	               01200 Carbon metabolism	COG3063	NW
LFTS_00270	499.731150179926	-0.242873977750152	0.160856370302306	-1.50988100311916	0.131073790852235	0.270190252121605	654	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01212	192.562030541061	0.298498219261563	0.19776105677076	1.50938826953972	0.131199589036902	0.270225499872193	312	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_02170	1519.04786200351	-0.199969451004085	0.132603889802568	-1.50802100377159	0.131549151456062	0.270665931511601	840	phosphatidate cytidylyltransferase	NA	K00981	 Lipid metabolism; Signal transduction	              Lipid metabolism	               00564 Glycerophospholipid metabolism	COG0575	I
LFTS_00052	2657.28143734021	-0.192473778155861	0.127684564396853	-1.50741617880794	0.131704014337789	0.270665931511601	1029	glyceraldehyde 3-phosphate dehydrogenase	NA	K00134	 Energy metabolism; Overview; Signal transduction; Neurodegenerative diseases; Carbohydrate metabolism	              Overview	               01200 Carbon metabolism	COG0057	G
LFTS_01892	285.684978322986	-0.290781214070037	0.192918424230932	-1.50727549859083	0.131740055160514	0.270665931511601	1575	apolipoprotein N-acyltransferase	NA	K03820	NA	              Drug resistance	               01503 Cationic antimicrobial peptide (CAMP) resistance	COG0815	M
LFTS_02526	140.916085220654	0.328348069112464	0.218508832322943	1.50267641642597	0.132922507103106	0.272819077954399	573	TPR repeat-containing protein	NA	K12284	NA	              Metabolism of cofactors and vitamins	               00860 Porphyrin and chlorophyll metabolism	NA	
LFTS_02135	47.3072632201548	0.442258899124893	0.294388316343525	1.50229772912868	0.133020234871955	0.272819077954399	528	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01918	681.390613764627	-0.211503201319475	0.140821701638323	-1.50192192580293	0.133117273354258	0.272819077954399	1098	carbamoyl-phosphate synthase small subunit	NA	K01956	 Nucleotide metabolism; Amino acid metabolism	              Nucleotide metabolism	               00240 Pyrimidine metabolism	COG0505	EF
LFTS_01643	1712.23819292926	0.362278659754135	0.241337484936709	1.50112884390564	0.133322239727175	0.273014075751035	660	Adenylate kinase	NA	K00939	 Metabolism of cofactors and vitamins; Nucleotide metabolism	              Nucleotide metabolism	               00230 Purine metabolism	COG0563	F
LFTS_01928	474.105766905855	0.253151509615546	0.168772323166708	1.49995867133671	0.133625108447758	0.273409069630556	348	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01800	269.446536028406	0.277259768643166	0.184921297163697	1.49933930215582	0.133785631351609	0.273512400937582	501	Transposase (or an inactivated derivative)	NA	K07493	NA	              Overview	               01200 Carbon metabolism	COG3328	X
LFTS_01209	117.581410165566	-0.378655571578548	0.252779483895887	-1.49796797486344	0.134141571202084	0.274014746103847	336	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00302	296.026835381922	0.253981782911071	0.169819407148492	1.49559927911529	0.134758111132308	0.275048164429325	381	Sulfur relay (sulfurtransferase) complex TusC component%2C DsrF/TusC family	NA	K07236	 Folding, sorting and degradation	              Folding, sorting and degradation	               04122 Sulfur relay system	COG2923	P
LFTS_01476	937.276939693646	0.205618918706266	0.137619541579519	1.49411134746046	0.135146518552543	0.275441212846361	1368	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00155	139.406619129032	0.339925570679867	0.227525208072392	1.49401278899924	0.135172276618086	0.275441212846361	315	Nucleoid-associated protein	NA	K09747	NA	              Nucleotide metabolism	               00230 Purine metabolism	COG0718	R
LFTS_00874	1138.02159575055	0.193110272501025	0.12953705284242	1.49077247215081	0.136021241396163	0.276944149148944	990	membrane fusion protein%2C multidrug efflux system	NA	K03543	NA	              Membrane transport	               02010 ABC transporters	COG1566	V
LFTS_00105	364.765089870146	0.261801851284167	0.175996027312786	1.48754409563395	0.136871165998461	0.278446578291469	1143	glutamate 5-kinase	NA	K00931	 Amino acid metabolism; Overview; Biosynthesis of other secondary metabolites	              Overview	               01230 Biosynthesis of amino acids	COG0263	E
LFTS_02264	573.996778196464	0.283654352160149	0.191135749669537	1.48404656193607	0.137796568449116	0.279885505950269	768	cyclase	NA	K02500	 Overview; Amino acid metabolism	              Overview	               01230 Biosynthesis of amino acids	COG0107	E
LFTS_01641	1266.94473796206	0.353729299269398	0.238358866868321	1.48401988949214	0.137803644120325	0.279885505950269	219	translation initiation factor IF-1	NA	K02518	NA	              Translation	               03010 Ribosome	COG0361	J
LFTS_02368	1305.42896364429	0.186159555450419	0.125558933592664	1.48264683462791	0.138168266840079	0.280396988868928	1557	exopolyphosphatase / guanosine-5'-triphosphate%2C3'-diphosphate pyrophosphatase	NA	K01524	 Nucleotide metabolism	              Nucleotide metabolism	               00230 Purine metabolism	COG0248	FTP
LFTS_00713	640.536574851899	-0.259869427675214	0.175643040185108	-1.47953159659125	0.138998293102932	0.281851351267446	378	Tetratricopeptide repeat-containing protein	NA	K02498	NA	              Cell motility	               02030 Bacterial chemotaxis	COG3071	S
LFTS_01637	2013.61029654959	0.28839578628287	0.195338549148803	1.47638951727434	0.139839355198979	0.283325702546587	465	large subunit ribosomal protein L17	NA	K02879	 Translation	              Translation	               03010 Ribosome	COG0203	J
LFTS_00122	1548.55604029194	0.200250331681007	0.135794244293358	1.47465993660529	0.140303992198464	0.284035606356174	2451	ATP-dependent proteinase. Serine peptidase. MEROPS family S16	NA	K01338	 Cell growth and death	              Cell growth and death	               04112 Cell cycle - Caulobacter	COG0466	O
LFTS_00743	14.0986041289237	-0.609809633072632	0.41394705394412	-1.47315852900103	0.140708294510039	0.284481584165033	264	hypothetical protein	NA	K08682	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00770 Pantothenate and CoA biosynthesis	COG3124	I
LFTS_01053	255.491549581441	-0.268655591364715	0.182387662062877	-1.47299213294426	0.140753157088894	0.284481584165033	624	hypothetical protein	NA	K06952	NA	              Replication and repair	               03030 DNA replication	COG3810	
LFTS_00040	752.732378380825	-0.240381145107739	0.163427748348804	-1.47087105792275	0.14132599103651	0.285407322271945	1227	hypothetical protein	NA	K09800	NA	              Signal transduction	               02020 Two-component system	COG2911	U
LFTS_00391	616.343821543087	0.267638218433586	0.182125392353517	1.46952720307162	0.141689848974306	0.285909873823154	1290	metabolite-proton symporter	NA	K08172	NA	              Carbohydrate metabolism	               00520 Amino sugar and nucleotide sugar metabolism	COG0477	GEPR
LFTS_01999	1407.78042235299	-0.209850450824884	0.142927999624502	-1.46822492007304	0.142043137276255	0.286390299488053	852	Dihydropteroate synthase	NA	K00796	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00790 Folate biosynthesis	COG0294	H
LFTS_01852	299.306022111298	-0.331491229667304	0.225903941163308	-1.46739905448425	0.142267531560041	0.286610278329224	1065	2%2C4-dienoyl-CoA reductase	NA	K09461	 Xenobiotics biodegradation and metabolism	              Xenobiotics biodegradation and metabolism	               00627 Aminobenzoate degradation	NA	
LFTS_02253	798.59466207837	0.208920760044972	0.142450772546658	1.46661724826057	0.142480205274165	0.286806307944595	1422	HD domain protein	NA	K06885	NA	              Replication and repair	               03030 DNA replication	COG1078	R
LFTS_01343	355.157251638454	-0.24900996845425	0.170038349126314	-1.46443416872551	0.143075357886435	0.287771310441487	2043	4-alpha-glucanotransferase	NA	K01196	 Carbohydrate metabolism	              Carbohydrate metabolism	               00500 Starch and sucrose metabolism	NA	
LFTS_02045	197.675749911356	-0.299783204466845	0.205600307527244	-1.45808733494779	0.144816471874302	0.290969908113051	606	transposase%2C IS605 OrfB family%2C central region	NA	K07496	NA	              Metabolism of cofactors and vitamins	               00860 Porphyrin and chlorophyll metabolism	COG0675	X
LFTS_01809	689.821896615971	0.289928013642926	0.198920563618827	1.45750649590199	0.144976619560579	0.290969908113051	1422	Glycosyltransferase involved in cell wall bisynthesis	Lipopolysaccharide synthesis	K12994	NA	              Glycan biosynthesis and metabolism	               00540 Lipopolysaccharide biosynthesis	COG0438	M
LFTS_01265	108.504284207955	0.353958283268966	0.242876201732723	1.45736091368262	0.145016780431243	0.290969908113051	294	mRNA interferase HigB	NA	K01638	 Carbohydrate metabolism; Overview	              Overview	               01200 Carbon metabolism	COG2225	C
LFTS_00158	449.257464188667	-0.219444142097941	0.150641837591792	-1.45672772986604	0.145191552097518	0.291085643963249	252	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01916	1374.72993612251	-0.183392952146723	0.126097208889853	-1.45437756918885	0.145841655301143	0.292153388459824	3243	carbamoyl-phosphate synthase large subunit	NA	K01955	 Nucleotide metabolism; Amino acid metabolism	              Nucleotide metabolism	               00240 Pyrimidine metabolism	COG0458	EF
LFTS_02351	516.524661366941	0.228255563294904	0.15727135698003	1.45134859695963	0.146682815514813	0.293601835241405	774	dihydrodipicolinate reductase	NA	K00215	 Amino acid metabolism; Overview; Biosynthesis of other secondary metabolites	              Overview	               01230 Biosynthesis of amino acids	COG0289	E
LFTS_00188	443.830547978424	-0.245602698439511	0.169618933519849	-1.4479674723976	0.147626147815309	0.295209937504814	405	glycine cleavage system H protein	NA	K02437	 Carbohydrate metabolism; Amino acid metabolism	              Carbohydrate metabolism	               00630 Glyoxylate and dicarboxylate metabolism	COG0509	E
LFTS_00014	229.960049039601	0.254891428161048	0.176076357503871	1.44761870233171	0.147723717721636	0.295209937504814	291	Transposase	NA	K07483	NA	              Replication and repair	               03410 Base excision repair	COG2963	X
LFTS_02164	1988.33152778119	-0.193098865014688	0.133723993769688	-1.44401060401517	0.148735992530812	0.296994118418955	183	LSU ribosomal protein L32P	NA	K02911	 Translation	              Translation	               03010 Ribosome	COG0333	J
LFTS_02415	1383.96429336449	0.220133724361711	0.153025879497193	1.43853918752187	0.150281126886441	0.299691407419931	1212	Virginiamycin B lyase	NA	NA	NA	NA	NA	NA	NA
LFTS_02451	11197.3585275659	0.213013953567554	0.148093558885767	1.43837419513879	0.150327910318847	0.299691407419931	699	pyruvate ferredoxin oxidoreductase gamma subunit	Reductive TCA cycle carbon dioxide fixation	K00172	 Carbohydrate metabolism; Overview; Energy metabolism; Xenobiotics biodegradation and metabolism	              Overview	               01200 Carbon metabolism	COG1014	C
LFTS_01307	373.002020738652	-0.241292622701352	0.167969752216633	-1.43652425223652	0.150853220399481	0.30049768102012	852	Glycosyl transferase family 2	Lipopolysaccharide synthesis	K00786	NA	              Glycan biosynthesis and metabolism	               00540 Lipopolysaccharide biosynthesis	NA	
LFTS_00556	100.941559386673	-0.356793182771518	0.249236263895538	-1.43154602462289	0.152273786246352	0.303082791146682	273	Putative zinc-finger	NA	NA	NA	NA	NA	NA	NA
LFTS_01546	703.761193543382	0.196428864364482	0.13730765234014	1.43057477873037	0.152552120133109	0.303082791146682	813	Exodeoxyribonuclease III	NA	K01142	 Replication and repair	              Replication and repair	               03410 Base excision repair	COG0708	L
LFTS_01742	37.2694553100597	-0.485475647460363	0.339577269706625	-1.42964706642405	0.152818339785629	0.303082791146682	414	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00497	1116.58668730491	0.296312905665486	0.207264498817255	1.42963656273207	0.152821355985144	0.303082791146682	2898	maltooligosyl trehalose synthase	NA	K06044	 Carbohydrate metabolism	              Carbohydrate metabolism	               00500 Starch and sucrose metabolism	COG3280	G
LFTS_00090	3891.69855369416	0.188412775297694	0.1317994455234	1.42954148668434	0.152848659715386	0.303082791146682	1761	threonyl-tRNA synthetase	NA	K01868	 Translation	              Translation	               00970 Aminoacyl-tRNA biosynthesis	COG0441	J
LFTS_01629	1725.54179726183	0.182534268097429	0.127697797993264	1.4294237721081	0.15288246987045	0.303082791146682	912	ADP-L-glycero-D-manno-heptose 6-epimerase	Lipopolysaccharide synthesis	K03274	 Glycan biosynthesis and metabolism	              Glycan biosynthesis and metabolism	               00540 Lipopolysaccharide biosynthesis	COG0451	M
LFTS_01915	4094.21914769535	0.216820681759119	0.151822426573125	1.4281202497754	0.153257249934315	0.303476142613746	483	transcription elongation factor GreA	NA	K03624	NA	              Nucleotide metabolism	               00240 Pyrimidine metabolism	COG0782	K
LFTS_02176	823.926262014634	0.190074146428283	0.133115888147444	1.42788474819587	0.153325034240895	0.303476142613746	300	sec-independent protein translocase protein TatB	NA	K03117	 Folding, sorting and degradation; Membrane transport	              Folding, sorting and degradation	               03060 Protein export	COG1826	U
LFTS_02421	2018.40111410009	-0.202646733387627	0.142068410397578	-1.42640248328619	0.153752197309341	0.304079524670662	1005	folate-binding protein YgfZ	NA	K06980	NA	              Carbohydrate metabolism	               00052 Galactose metabolism	COG0354	O
LFTS_01898	2069.65279146712	-0.229836512443586	0.161417925183318	-1.42385991012192	0.154487028915116	0.30528994744275	657	Lon protease	NA	K07157	NA	              Overview	               01200 Carbon metabolism	COG2802	S
LFTS_00289	741.906207911788	-0.203056135195744	0.142767146716602	-1.42228894998384	0.154942385402242	0.305946600563919	726	Outer membrane protein beta-barrel domain protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01182	5.58271008421814	0.604459631762475	0.425482401308233	1.42064543657726	0.155419862321364	0.306645855341993	312	ferredoxin III%2C nif-specific	Nitrogenase genes	K03616	NA	              Signal transduction	               02020 Two-component system	COG2878	C
LFTS_02380	2551.72136932136	0.207340160169585	0.146080460420975	1.41935587806932	0.155795288922061	0.307142813846347	603	Peroxiredoxin	Oxidative stress response	K02199	NA	              Nucleotide metabolism	               00240 Pyrimidine metabolism	COG0526	O
LFTS_01560	603.122910422011	-0.221058586683677	0.156183793067446	-1.41537468351928	0.156958668334753	0.309191164405861	1503	adenosylcobyric acid synthase (glutamine-hydrolysing)	NA	K02232	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00860 Porphyrin and chlorophyll metabolism	COG1492	H
LFTS_00885	811.300460474675	0.209789289283783	0.148404996736369	1.41362685824157	0.15747149102635	0.30988598589137	552	shikimate kinase	NA	K00891	 Overview; Amino acid metabolism	              Overview	               01230 Biosynthesis of amino acids	COG0703	E
LFTS_01886	1360.43787721682	-0.250836608064658	0.17747999557246	-1.41332327204306	0.157560694355065	0.30988598589137	1008	putative oxidoreductase	NA	K05275	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00750 Vitamin B6 metabolism	COG0667	R
LFTS_01336	11537.7417823531	0.220392616007233	0.156118435135003	1.41170141640639	0.158037896136141	0.310578821971894	663	16S rRNA (guanine966-N2)-methyltransferase	NA	K08316	NA	              Cell growth and death	               04112 Cell cycle - Caulobacter	COG0742	J
LFTS_02359	1210.60530406783	0.196697120395187	0.139706865945415	1.4079273703845	0.15915257746782	0.312509172881662	1044	voltage-gated potassium channel	Role of potassium in the internal positive membrane potential	K03499	NA	              Overview	               01200 Carbon metabolism	COG0569	P
LFTS_00667	363.868949287426	-0.221543059480139	0.157398947332018	-1.40752567431607	0.159271569606221	0.312509172881662	717	outer membrane lipoprotein carrier protein	NA	K03634	NA	              Metabolism of cofactors and vitamins	               00750 Vitamin B6 metabolism	COG2834	M
LFTS_00892	412.381432502495	0.230213585677745	0.163815492936727	1.40532242433666	0.159925423128649	0.313353117081284	450	7-cyano-7-deazaguanine reductase	NA	K09457	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00790 Folate biosynthesis	COG0780	J
LFTS_00601	251.82016373623	-0.288701870314464	0.205448562615004	-1.40522701468334	0.159953783417598	0.313353117081284	1116	UDP-N-acetylglucosamine-N- acetylmuramylpentapeptide N-acetylglucosamine transferase	NA	K02563	 Cell growth and death; Glycan biosynthesis and metabolism; Drug resistance	              Glycan biosynthesis and metabolism	               00550 Peptidoglycan biosynthesis	COG0707	M
LFTS_01368	1173.5696841399	-0.231621168921776	0.164900630579403	-1.4046105712752	0.160137111395619	0.313465243251582	1203	GTP cyclohydrolase II /3%2C4-dihydroxy-2-butanone 4-phosphate synthase (EC 4.1.99.12)	NA	K14652	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00740 Riboflavin metabolism	COG0108;COG0807	H
LFTS_00131	169.96296808096	0.271379482907793	0.193396651577305	1.40322741213188	0.160549035802165	0.313819293770179	201	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01870	2104.02848076508	0.238900531188224	0.170495131513787	1.40121614656724	0.161149447322918	0.313819293770179	951	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD%2C containing LysM domain	NA	K08259	NA	              Overview	               01200 Carbon metabolism	NA	
LFTS_00558	73.3168333697515	-0.363590700064188	0.259486974187113	-1.40119056535765	0.161157094842109	0.313819293770179	462	mercuric ion transport protein	Mercury resistance	NA	NA	NA	NA	NA	NA
LFTS_01044	22.3300805925216	0.523906054534698	0.373908771087671	1.40116010921781	0.161166200082321	0.313819293770179	246	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00827	672.854374822184	0.199246714299056	0.142216910708763	1.40100578268839	0.161212343882726	0.313819293770179	360	hypothetical protein	NA	K14945	NA	              Overview	               01212 Fatty acid metabolism	NA	
LFTS_00119	447.197737254405	-0.258365328388458	0.184426569872269	-1.40091163961569	0.161240497663894	0.313819293770179	480	hypothetical protein	NA	K02015	 Membrane transport	              Membrane transport	               02010 ABC transporters	COG0609	P
LFTS_00767	1675.38794310827	0.182210376584837	0.130069266619014	1.40087186866786	0.161252392406274	0.313819293770179	195	Zn-finger domain of CDGSH type-containing protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01379	433.319665485934	-0.246521150886547	0.176011991818938	-1.40059292744179	0.161335837105303	0.313819293770179	2913	iron complex outermembrane recepter protein	NA	K02014	NA	              Metabolism of cofactors and vitamins	               00785 Lipoic acid metabolism	COG1629	P
LFTS_01737	75.4500448490593	-0.398537424886696	0.284690492697918	-1.39989720453917	0.161544103290269	0.313819293770179	1470	DNA-3-methyladenine glycosylase II	NA	K13529	 Replication and repair	              Replication and repair	               03410 Base excision repair	COG2169;COG0122	L
LFTS_02197	343.720321196246	0.265475744322908	0.189655841028602	1.39977626253478	0.161580328248524	0.313819293770179	693	phosphoglycolate phosphatase	NA	K01091	 Carbohydrate metabolism	              Carbohydrate metabolism	               00630 Glyoxylate and dicarboxylate metabolism	COG0546	C
LFTS_01435	2762.8281530304	-0.182726334487827	0.130607953458873	-1.39904446588979	0.161799649301799	0.313999943922148	1314	N-acetylmuramoyl-L-alanine amidase	NA	K01448	 Drug resistance	              Drug resistance	               01503 Cationic antimicrobial peptide (CAMP) resistance	COG0860	M
LFTS_02519	846.937280194167	0.218411611578197	0.156259661548456	1.39774788588331	0.162188788880959	0.314509617127974	1047	Thiol-disulfide isomerase or thioredoxin	NA	K02199	NA	              Nucleotide metabolism	               00240 Pyrimidine metabolism	COG0526	O
LFTS_00842	947.767119249384	0.200835006832578	0.143760932331871	1.39700684723547	0.16241151207033	0.314664471394553	246	SSU ribosomal protein S16P	NA	K02959	 Translation	              Translation	               03010 Ribosome	COG0228	J
LFTS_00145	681.5020215437	0.223460321916861	0.160002315126578	1.39660680372082	0.162531843196529	0.314664471394553	906	tetrapyrrole methylase family protein / MazG family protein	NA	K02499	NA	              Overview	               01230 Biosynthesis of amino acids	COG3956	R
LFTS_02157	713.08983778832	0.224182291559555	0.160563773632599	1.39621962344089	0.162648369164119	0.314664471394553	756	ribonuclease-3	NA	K03685	 Translation; Cancers	              Translation	               03008 Ribosome biogenesis in eukaryotes	COG0571	K
LFTS_00793	1973.29820930107	-0.193280768694779	0.138545734204988	-1.39506834911862	0.162995229547518	0.314849745610208	474	Nucleotide-binding universal stress protein%2C UspA family	NA	K06149	NA	              Cell growth and death	               04112 Cell cycle - Caulobacter	COG0589	T
LFTS_02295	2694.37966539022	-0.186382850210719	0.133601932395889	-1.39506103593195	0.162997434674311	0.314849745610208	1299	Adenylosuccinate synthetase	NA	K01939	 Amino acid metabolism; Nucleotide metabolism	              Nucleotide metabolism	               00230 Purine metabolism	COG0104	F
LFTS_00598	526.033262689509	-0.241767426618138	0.173514581676423	-1.39335509605178	0.16351243739491	0.3155993162762	1464	UDP-N-acetylmuramoylalanine--D-glutamate ligase	NA	K01925	 Metabolism of other amino acids; Glycan biosynthesis and metabolism	              Metabolism of other amino acids	               00471 D-Glutamine and D-glutamate metabolism	COG0771	M
LFTS_00565	269.046148431316	-0.265776237117344	0.190898075855396	-1.39224157145863	0.16384925807072	0.316004077241124	1104	UDP-galactopyranose mutase	Extracellular polysaccharide production and export	K01854	 Carbohydrate metabolism	              Carbohydrate metabolism	               00052 Galactose metabolism	COG0562	M
LFTS_00629	39036.6254600712	-0.334141391285644	0.240614825746633	-1.3886982659892	0.164924521710806	0.317831287576019	576	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01531	24203.2465074835	-0.255134510518068	0.184055117970095	-1.38618536301458	0.165690309752772	0.319059728927492	531	cytochrome c oxidase cbb3-type subunit 2	Cytochrome cbb3 oxidase; Proton transporters	K00405	 Energy metabolism; Signal transduction	              Energy metabolism	               00190 Oxidative phosphorylation	COG2993	C
LFTS_01012	146.374889389311	-0.286155227583722	0.206557428938303	-1.38535432520897	0.165944149951803	0.319121333434381	1098	transposase%2C IS605 OrfB family%2C central region	NA	K07496	NA	              Replication and repair	               03410 Base excision repair	COG0675	X
LFTS_01591	1331.87059644139	0.175474874705506	0.126674692482748	1.38524018702002	0.165979036255292	0.319121333434381	576	elongation factor P	NA	K02356	NA	              Overview	               01230 Biosynthesis of amino acids	COG0231	J
LFTS_01099	68.4109385008543	0.373355743838653	0.269965851241449	1.38297396549142	0.166672848818931	0.320207652367746	2010	hypothetical protein	NA	K14440	NA	              Amino acid metabolism	               00310 Lysine degradation	NA	
LFTS_00306	1569.84937689809	0.240514049966969	0.173982360575342	1.38240479765657	0.166847443826928	0.320295556257717	1098	GGDEF domain-containing protein%2C diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	Putative diguanylate cyclases (GGDEF domain-containing proteins)	K02488	 Cell growth and death; Signal transduction	              Signal transduction	               02020 Two-component system	COG3706	TK
LFTS_00005	652.890985398341	0.221943539621961	0.160671723461957	1.38134784914105	0.167172032539029	0.320671043898168	816	Tetratricopeptide repeat-containing protein	NA	K05807	NA	              Nucleotide metabolism	               00230 Purine metabolism	COG4105	M
LFTS_00139	553.960879273421	-0.235693620495984	0.171420682342758	-1.37494272730003	0.169149201343763	0.324213503886349	990	Phosphoesterase family protein	NA	K01114	 Lipid metabolism; Cellular community - prokaryotes; Carbohydrate metabolism; Endocrine system	              Carbohydrate metabolism	               00562 Inositol phosphate metabolism	COG3511	M
LFTS_00243	123.532560836947	-0.313277886935637	0.229545277001906	-1.36477600858255	0.172323461529966	0.330043239879427	714	Tetratricopeptide repeat-containing protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01198	21.342709654678	-0.540695828897852	0.396859445372095	-1.36243658857835	0.173060143361002	0.33119901185177	294	molybdopterin synthase sulfur carrier subunit	NA	K03636	 Folding, sorting and degradation	              Folding, sorting and degradation	               04122 Sulfur relay system	COG1977	H
LFTS_02450	4088.0325143041	0.194677799315987	0.143737970923522	1.3543936794514	0.175610813022368	0.335821908595082	213	pyruvate ferredoxin oxidoreductase	Reductive TCA cycle carbon dioxide fixation	K00171	 Carbohydrate metabolism; Overview; Energy metabolism; Xenobiotics biodegradation and metabolism	              Overview	               01200 Carbon metabolism	COG1144	C
LFTS_01951	1157.12888457453	-0.238272918766827	0.176369690381058	-1.3509856384735	0.176700033219914	0.337444252055073	1239	tryptophan synthase beta chain	NA	K01696	 Overview; Amino acid metabolism	              Overview	               01230 Biosynthesis of amino acids	COG0133	E
LFTS_00432	4129.14730782846	-0.291558496283287	0.215826963661412	-1.35089004328802	0.176730658155955	0.337444252055073	1338	B12 binding domain-containing protein	NA	K13602	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00860 Porphyrin and chlorophyll metabolism	COG1032	R
LFTS_01952	374.002781038119	-0.234961192660786	0.174062101758794	-1.34986990439988	0.177057716869868	0.337809274089404	639	phosphoribosylanthranilate isomerase	NA	K01817	 Overview; Amino acid metabolism	              Overview	               01230 Biosynthesis of amino acids	COG0135	E
LFTS_00464	225.349629633729	-0.304245286820297	0.226248240699801	-1.34474100607035	0.178708887371917	0.340473328901488	888	putative iron-dependent peroxidase	Oxidative stress response	K07223	NA	              Lipid metabolism	               00564 Glycerophospholipid metabolism	COG2837	P
LFTS_02318	240.939641334582	-0.268110237712834	0.199385609672818	-1.34468198659266	0.178727954230266	0.340473328901488	1017	flagellar motor switch protein FliM	Chemotaxis	K02416	 Cell motility	              Cell motility	               02030 Bacterial chemotaxis	COG1868	N
LFTS_02480	1502.45723059624	0.170569228106754	0.127356966462839	1.33930033702965	0.180472919080129	0.343534208907504	1281	hypothetical protein	NA	K02012	 Membrane transport	              Membrane transport	               02010 ABC transporters	COG1840	P
LFTS_02306	383.895273578099	-0.228768847494892	0.171024392278096	-1.3376387101724	0.181014239210217	0.344145597933949	1101	Cellulase family 8	Cellulose production	K15531	NA	              Glycan biosynthesis and metabolism	               00550 Peptidoglycan biosynthesis	COG3405	G
LFTS_00290	325.67858501007	-0.257653469070054	0.192693921296706	-1.3371125946071	0.181185886672091	0.344145597933949	999	Holliday junction DNA helicase subunit RuvB	NA	K03551	 Replication and repair	              Replication and repair	               03440 Homologous recombination	COG2255	L
LFTS_01868	584.805089000665	0.213721907528256	0.15984699257676	1.33704052908987	0.181209407761681	0.344145597933949	531	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_02294	276.933253691068	-0.229795257696505	0.172973190953088	-1.32850215938277	0.184012270681482	0.349201912148217	315	hypothetical protein	NA	K06475	 Immune system	              Immune system	               04640 Hematopoietic cell lineage	NA	
LFTS_01226	124.000393207193	0.298963068586112	0.225354396457439	1.32663517235873	0.184629395109753	0.349596576919545	678	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_02362	5875.36991706933	0.259102903405964	0.195312869038924	1.32660435884707	0.184639593214868	0.349596576919545	117	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00373	3135.94993369798	0.192778883476302	0.145318376777134	1.3265967302398	0.184642118059277	0.349596576919545	561	5-methylcytosine-specific restriction endonuclease McrA	NA	K09952	NA	              Overview	               01210 2-Oxocarboxylic acid metabolism	COG3513	V
LFTS_02101	1488.10993426161	-0.205485354285926	0.155102650007949	-1.32483458068186	0.185226022551266	0.350435229880097	1479	aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit A	NA	K02433	 Translation	              Translation	               00970 Aminoacyl-tRNA biosynthesis	COG0154	J
LFTS_00543	140.896115241639	-0.278305071517781	0.210348474622084	-1.3230667444477	0.18581318274093	0.351278762200725	1512	O-antigen ligase	Extracellular polysaccharide production and export	K13009	NA	              Cell motility	               02030 Bacterial chemotaxis	COG3307	M
LFTS_01416	260.940621324166	0.232287969519072	0.175663376651408	1.32234717302532	0.186052571204317	0.351464051682319	942	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01340	247.994970621743	0.243300807734269	0.184158753770563	1.32114712308158	0.186452313222774	0.351951746903429	1239	lipoprotein-releasing system permease protein	NA	K09808	 Membrane transport	              Membrane transport	               02010 ABC transporters	COG4591	M
LFTS_02518	525.472531292	0.204196007438943	0.154810237378801	1.31900842538792	0.187166295751363	0.35294527716321	417	secondary thiamine-phosphate synthase enzyme	NA	NA	NA	NA	NA	NA	NA
LFTS_02187	575.567796855125	0.184609550734743	0.139991425389003	1.3187204160666	0.187262598784503	0.35294527716321	1476	squalene-associated FAD-dependent desaturase	NA	K02293	 Metabolism of terpenoids and polyketides	              Metabolism of terpenoids and polyketides	               00906 Carotenoid biosynthesis	COG3349	R
LFTS_02165	3863.21575937702	0.167352577219591	0.126965009987712	1.31809998074106	0.187470180963204	0.353068840814033	495	hypothetical protein	NA	K07040	NA	              Translation	               03010 Ribosome	COG1399	S
LFTS_02146	494.447780414521	-0.193455425476704	0.146862581607361	-1.31725469727823	0.187753265031452	0.353146177800599	1347	N-acetylglutamate synthase	NA	K14682	 Overview; Amino acid metabolism	              Overview	               01210 2-Oxocarboxylic acid metabolism	COG0548;COG1246	E
LFTS_00369	1340.23508395122	-0.189525079376975	0.143892560529069	-1.31712910438262	0.187795352796618	0.353146177800599	924	TIGR00269 family protein	NA	K14168	 Folding, sorting and degradation	              Folding, sorting and degradation	               04122 Sulfur relay system	NA	
LFTS_01947	361.645531393828	0.221155380486424	0.168371015982966	1.31350030285972	0.189014418926015	0.355169951209428	2301	LPS-assembly protein	NA	K04744	NA	              Energy metabolism	               00190 Oxidative phosphorylation	COG1452	M
LFTS_00085	1071.84643803849	-0.229449269530281	0.174757690756937	-1.31295663462052	0.189197561209686	0.35524557187861	825	thiazole synthase	NA	K03149	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00730 Thiamine metabolism	COG2022	H
LFTS_01176	1.17024106745092	-0.385112366265878	0.293830954100856	-1.3106596187061	0.18997278725349	0.356431961594096	246	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01239	268.961328216274	-0.296279049946035	0.22649576237096	-1.30809974917227	0.190839478535195	0.357659662290957	984	NADPH2:quinone reductase	NA	K00344	NA	              Biosynthesis of other secondary metabolites	               00405 Phenazine biosynthesis	COG0604	CR
LFTS_00887	1421.98553831499	0.20974306470038	0.160369047822553	1.30787747104702	0.190914872027393	0.357659662290957	753	3-dehydroquinate synthase	NA	K01735	 Overview; Amino acid metabolism	              Overview	               01230 Biosynthesis of amino acids	COG0337	E
LFTS_02166	2140.89696394167	0.166033165813496	0.127018293324322	1.30715947654528	0.191158555050279	0.357846511939002	1269	prolyl-tRNA synthetase	NA	K01881	 Translation	              Translation	               00970 Aminoacyl-tRNA biosynthesis	COG0442	J
LFTS_00178	879.498714453214	0.239133183469634	0.183105110593342	1.30598858051933	0.191556441001927	0.358321529218051	306	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01979	1053.20572047756	-0.212379363534225	0.162845123262747	-1.30418006556792	0.19217219499183	0.359064330567233	1107	Dihydroorotate dehydrogenase	NA	K00226	 Nucleotide metabolism	              Nucleotide metabolism	               00240 Pyrimidine metabolism	COG0167	F
LFTS_01866	105.27507570103	0.327815675348377	0.251397378793382	1.30397411827353	0.192242407073607	0.359064330567233	771	Sulfite exporter TauE/SafE	NA	K07090	NA	              Metabolism of cofactors and vitamins	               00790 Folate biosynthesis	COG0730	S
LFTS_00927	22735.2565009282	-0.188911490169039	0.144935531211212	-1.30341737868088	0.192432306570221	0.359149184784961	2442	ATP-dependent Clp protease ATP-binding subunit ClpC	Chaperones	K03696	NA	              Translation	               00970 Aminoacyl-tRNA biosynthesis	COG0542	O
LFTS_01917	424.428982418909	-0.221275503711242	0.169919979569043	-1.30223358237477	0.192836548418662	0.359633652939831	999	putative pyruvate formate lyase activating enzyme	NA	K04070	NA	              Nucleotide metabolism	               00240 Pyrimidine metabolism	COG1313	R
LFTS_01958	393.475284741765	0.241540183742799	0.185773522789333	1.3001862704445	0.193537135093035	0.360669653554187	597	ADP-ribose pyrophosphatase	NA	K01515	 Nucleotide metabolism	              Nucleotide metabolism	               00230 Purine metabolism	COG0494	V
LFTS_00773	753.181243930992	-0.184882748148264	0.142312245123441	-1.29913450517134	0.193897773336894	0.361071059562187	834	short chain dehydrogenase	NA	K07124	NA	              Replication and repair	               03440 Homologous recombination	COG0300	R
LFTS_00387	117.038330155766	-0.335303681139034	0.258255103478013	-1.29834290445138	0.194169529356449	0.361111511494918	513	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_02531	4678.84515029052	0.206503952472773	0.159085817214399	1.29806639013249	0.194264522394215	0.361111511494918	582	CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit	NA	K00201	 Energy metabolism; Overview	              Overview	               01200 Carbon metabolism	COG1029	C
LFTS_02370	700.480607424761	-0.210077398613763	0.161871646050923	-1.29780232510686	0.194355270466693	0.361111511494918	690	dTMP kinase	NA	K00943	 Nucleotide metabolism	              Nucleotide metabolism	               00240 Pyrimidine metabolism	COG0125	F
LFTS_01793	354.172051185647	0.263535182168523	0.203203494496318	1.2969028058388	0.19466463097947	0.361416185672115	1578	Transposase	NA	K07108	NA	              Metabolism of other amino acids	               00450 Selenocompound metabolism	COG2522	R
LFTS_00721	2140.47986343135	0.17002660062751	0.131332164755896	1.2946303058625	0.195447792630423	0.362599412297934	480	general secretion pathway protein G	NA	K02456	 Cellular community - prokaryotes; Membrane transport	              Membrane transport	               03070 Bacterial secretion system	COG2165	NUW
LFTS_01140	496.219388117421	0.2058672978668	0.159208360915164	1.29306838336524	0.195987408948067	0.363102169838299	885	CRISP-associated protein Cas1	NA	K15342	NA	              Metabolism of cofactors and vitamins	               00860 Porphyrin and chlorophyll metabolism	COG1518	V
LFTS_02460	1155.21611628575	0.199812759121036	0.154534176832162	1.29300044311913	0.196010905841914	0.363102169838299	213	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_02185	812.969870670574	0.214307486171501	0.166019928795858	1.29085398196393	0.19675431502101	0.364207912987513	1059	CubicO group peptidase%2C beta-lactamase class C family	NA	K01453	 Xenobiotics biodegradation and metabolism	              Xenobiotics biodegradation and metabolism	               00930 Caprolactam degradation	NA	
LFTS_00868	799.041665363652	-0.201289788917927	0.156089740084054	-1.2895773214148	0.19719745401643	0.364756600211938	879	nicotinate-nucleotide pyrophosphorylase [carboxylating]	NA	K00767	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00760 Nicotinate and nicotinamide metabolism	COG0157	H
LFTS_01137	224.23689501602	0.240455646833605	0.186644447803343	1.28830859778352	0.197638561412591	0.365300716484537	651	CRISPR-associated protein%2C Cse3 family	NA	K05682	 Membrane transport	              Membrane transport	               02010 ABC transporters	NA	
LFTS_00828	1304.47861672179	0.173344166821217	0.134716541220323	1.28673261093989	0.198187502421879	0.366043187979786	948	exopolyphosphatase / guanosine-5'-triphosphate%2C3'-diphosphate pyrophosphatase	NA	K01524	 Nucleotide metabolism	              Nucleotide metabolism	               00230 Purine metabolism	COG0248	FTP
LFTS_00858	1807.36690563289	0.167086170998955	0.130107717652748	1.28421414204575	0.199067038278884	0.367333913481886	2223	diguanylate cyclase (GGDEF) domain-containing protein	Putative diguanylate cyclases (GGDEF domain-containing proteins)	K13590	 Cell growth and death	              Cell growth and death	               04112 Cell cycle - Caulobacter	COG2199	T
LFTS_01681	730.354346635248	0.179978221033666	0.140182405827134	1.28388594825235	0.199181864591144	0.367333913481886	570	hypothetical protein	NA	K02496	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00860 Porphyrin and chlorophyll metabolism	COG2959	S
LFTS_00084	1948.00927820165	-0.225934507866077	0.176129960653587	-1.28277157973393	0.199572113785453	0.36778078196489	1926	acetyl-CoA synthetase	NA	K01895	 Carbohydrate metabolism; Overview; Energy metabolism	              Overview	               01200 Carbon metabolism	COG0365	I
LFTS_00468	658.700029011723	0.21260783797609	0.165839164196214	1.28201223761922	0.199838353365153	0.36779571698593	1173	cysteine desulfurase	NA	K04487	 Metabolism of cofactors and vitamins; Folding, sorting and degradation	              Metabolism of cofactors and vitamins	               00730 Thiamine metabolism	COG1104	E
LFTS_01364	421.09158191329	-0.213373019083808	0.166496072490029	-1.28154986416623	0.200000597178783	0.36779571698593	1473	cysteinyl-tRNA synthetase	NA	K01883	 Translation	              Translation	               00970 Aminoacyl-tRNA biosynthesis	COG0215	J
LFTS_01715	672.827402556598	0.205659818926093	0.160485792534736	1.28148302524399	0.200024058473442	0.36779571698593	327	hypothetical protein	NA	K01907	 Amino acid metabolism; Carbohydrate metabolism	              Carbohydrate metabolism	               00650 Butanoate metabolism	COG0365	I
LFTS_01654	1495.86965911909	0.22529749869852	0.175985728386666	1.28020323445495	0.200473668692222	0.368349992881643	285	SSU ribosomal protein S19P	NA	K02965	 Translation	              Translation	               03010 Ribosome	COG0185	J
LFTS_00970	77.584264093091	-0.395086200156815	0.308968162184091	-1.27872787074227	0.200992901565291	0.369031280126523	273	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01816	331.017727383386	0.277641027249223	0.2176877752775	1.27540936506562	0.202164385650189	0.370908238174443	1089	Glycosyltransferase involved in cell wall bisynthesis	Lipopolysaccharide synthesis	K12994	NA	              Membrane transport	               02010 ABC transporters	COG0438	M
LFTS_00679	575.109677558353	0.211694158890629	0.166046912423256	1.27490572273345	0.20234261329397	0.370961457705611	294	Exodeoxyribonuclease VII small subunit	NA	K03602	 Replication and repair	              Replication and repair	               03430 Mismatch repair	COG1722	L
LFTS_02532	187.210223977912	0.239006762493249	0.187654362667943	1.27365417512927	0.202786003470376	0.371500371869827	513	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00411	831.397696762663	-0.211252696797694	0.166059744434655	-1.27214875294971	0.203320271848347	0.37220485700662	807	tRNA pseudouridine38-40 synthase	NA	K06173	NA	              Amino acid metabolism	               00310 Lysine degradation	COG0101	J
LFTS_00862	1931.83597397437	0.206939494341511	0.162860579051883	1.27065429550994	0.203851661888358	0.372903040069506	1083	recombination protein RecA	NA	K03553	 Replication and repair	              Replication and repair	               03440 Homologous recombination	COG0468	L
LFTS_00473	1662.81542365195	-0.19190433005025	0.151217176783778	-1.26906436247418	0.204418109462425	0.373664279502638	414	monothiol glutaredoxin	Oxidative stress response	K07390	NA	              Translation	               00970 Aminoacyl-tRNA biosynthesis	COG0278	O
LFTS_01832	39.0438901274519	0.418247047355804	0.330331988100605	1.26614152556253	0.205462417959647	0.375297260137901	306	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01796	337.398395482764	0.225982845048276	0.178595877349791	1.26533069184836	0.205752808791149	0.37555174937944	279	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00381	53.675857840569	-0.401328981910897	0.317542251153478	-1.26386010193309	0.206280244429135	0.376238215444483	702	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00285	260.708833498044	0.223019078351375	0.176842278367498	1.26111855383313	0.207266136829911	0.377504647055919	195	prevent-host-death family protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00257	288.485807036515	-0.260128310225811	0.206273447964057	-1.26108480171979	0.207278295748725	0.377504647055919	597	HslV component of HslUV peptidase. Threonine peptidase. MEROPS family T01B	NA	K01419	NA	              Nucleotide metabolism	               00230 Purine metabolism	COG0638	O
LFTS_02379	995.710797307843	-0.221071376386002	0.175683244273184	-1.25835208303781	0.208264452974209	0.378649845459642	516	Peroxiredoxin	Oxidative stress response	K02199	NA	              Overview	               01200 Carbon metabolism	COG0526	O
LFTS_02222	47.7499903365774	-0.402145579223082	0.319605550607711	-1.25825592971845	0.208299213699141	0.378649845459642	702	conjugal transfer/type IV secretion protein DotA/TraY	NA	K12202	NA	              Lipid metabolism	               00564 Glycerophospholipid metabolism	NA	
LFTS_02405	1703.43488709263	0.232924998297507	0.18514372458053	1.25807665814886	0.208364034026062	0.378649845459642	846	rod shape-determining protein MreC	NA	K03570	NA	              Overview	               01200 Carbon metabolism	COG1792	D
LFTS_00008	2383.12226806559	0.167546969807606	0.133254019277656	1.25735021514432	0.208626848180064	0.378850507359853	1584	leucyl aminopeptidase	NA	K01255	 Metabolism of other amino acids	              Metabolism of other amino acids	               00480 Glutathione metabolism	COG0260	E
LFTS_02005	195.978318635334	-0.310298024232079	0.247012753060021	-1.25620244456237	0.209042580679375	0.379328361729143	660	transcriptional regulator%2C TetR family	NA	K09017	NA	              Membrane transport	               02060 Phosphotransferase system (PTS)	COG1309	K
LFTS_02178	847.24091944534	0.191072059131231	0.152257916105146	1.25492364547589	0.209506479332997	0.379892857492218	615	ribosomal-protein-alanine N-acetyltransferase	NA	K03789	NA	              Energy metabolism	               00910 Nitrogen metabolism	COG0456	J
LFTS_02399	555.561388693167	0.217051668710384	0.173225652106808	1.25299957639388	0.210205860859404	0.380652361682247	399	dihydroneopterin aldolase	NA	K01633	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00790 Folate biosynthesis	COG1539	H
LFTS_01961	1549.4058273379	-0.197102060242146	0.157313041620324	-1.25292892573938	0.210231573849447	0.380652361682247	468	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01615	479.561809698747	-0.192030022278901	0.153453443782816	-1.25138946083662	0.210792420517984	0.380958777432365	624	hypothetical protein	NA	K02415	NA	              Membrane transport	               03070 Bacterial secretion system	COG1580	N
LFTS_00882	1407.58346578215	0.167234566702405	0.133661037751273	1.25118411106166	0.210867313791668	0.380958777432365	867	hypothetical protein	NA	K06958	NA	              Cellular community - prokaryotes	               02024 Quorum sensing	COG1660	T
LFTS_01369	483.705990329147	-0.230659226977935	0.184404247191862	-1.25083467702318	0.21099480038529	0.380958777432365	486	6%2C7-dimethyl-8-ribityllumazine synthase	NA	K00794	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00740 Riboflavin metabolism	COG0054	H
LFTS_02172	1091.17850411029	0.175965901595267	0.140684631243627	1.25078269061631	0.211013771731443	0.380958777432365	1929	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00384	170.025389426204	-0.277332628874029	0.222116527019677	-1.24859069514202	0.211814817374511	0.382127457179269	1767	hypothetical protein	NA	K09817	 Membrane transport	              Membrane transport	               02010 ABC transporters	COG1121	P
LFTS_00491	565.772502399409	0.229220304324121	0.183769430510002	1.24732554096719	0.212278156029689	0.382685638788838	1278	MFS transporter%2C MHS family%2C proline/betaine transporter	NA	K03762	NA	              Metabolism of cofactors and vitamins	               00790 Folate biosynthesis	COG0477	GEPR
LFTS_01304	407.459149181132	-0.196456435198986	0.157589340724783	-1.24663530093752	0.212531251805963	0.382864269557698	1209	heptosyltransferase-1	Lipopolysaccharide synthesis	K02841	 Glycan biosynthesis and metabolism	              Glycan biosynthesis and metabolism	               00540 Lipopolysaccharide biosynthesis	COG0859	M
LFTS_02461	1487.50846586864	-0.179948344820973	0.144519991491735	-1.24514500010376	0.213078455351274	0.383572078206566	1314	glutamate-1-semialdehyde 2%2C1-aminomutase	NA	K01845	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00860 Porphyrin and chlorophyll metabolism	COG0001	H
LFTS_00322	745.789648780057	-0.177989679850069	0.143070404544823	-1.2440705708238	0.213473591071412	0.383753939622702	2106	Excinuclease ABC subunit B	NA	K03702	 Replication and repair	              Replication and repair	               03420 Nucleotide excision repair	COG0556	L
LFTS_02319	359.586840011444	0.197940220296603	0.15911198839541	1.24403083823389	0.213488213394287	0.383753939622702	1143	HlyD family secretion protein	NA	K02005	NA	              Energy metabolism	               00190 Oxidative phosphorylation	COG0845	MV
LFTS_02047	3895.08572595201	0.188671396619542	0.151811301810119	1.24280204681682	0.213940788095244	0.384152082814398	390	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01194	37.0022319981939	-0.428471398490255	0.344821070065948	-1.24259053661747	0.21401875892918	0.384152082814398	501	molybdenum cofactor synthesis domain-containing protein	NA	K15376	 Metabolism of cofactors and vitamins; Nervous system	              Metabolism of cofactors and vitamins	               00790 Folate biosynthesis	NA	
LFTS_02027	15.8592748190799	-0.49924030633254	0.402002893681282	-1.24188236995217	0.214279965727605	0.384343430590784	228	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01713	160.891535462167	0.525076565843744	0.423378345550837	1.24020647574829	0.214899033798455	0.385175917824772	231	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01365	81.2130969120712	-0.324939177863885	0.262263183476366	-1.23898129183339	0.215352426403922	0.385710469769561	579	23S rRNA (guanosine2251-2'-O)-methyltransferase	NA	K03218	NA	              Metabolism of cofactors and vitamins	               00760 Nicotinate and nicotinamide metabolism	COG0566	J
LFTS_01356	1032.42646161865	-0.160312155005185	0.129550599934533	-1.23744818693389	0.215920738727631	0.386444387208101	1203	2%2C3-bisphosphoglycerate-independent phosphoglycerate mutase	Oxidative stress response	K15635	 Energy metabolism; Overview; Amino acid metabolism; Carbohydrate metabolism	              Overview	               01200 Carbon metabolism	COG3635	G
LFTS_01117	38.8978415144541	0.389949243600964	0.315228262756662	1.237037695132	0.216073088583773	0.386444387208101	519	hypothetical protein	NA	K02650	 Signal transduction	              Signal transduction	               02020 Two-component system	COG2165	NUW
LFTS_02107	1364.80495290549	-0.171845041935081	0.139266890237863	-1.23392603684606	0.217230466389654	0.388235039140676	1410	bifunctional UDP-N-acetylglucosamine pyrophosphorylase / Glucosamine-1-phosphate N-acetyltransferase	NA	K04042	 Carbohydrate metabolism	              Carbohydrate metabolism	               00520 Amino sugar and nucleotide sugar metabolism	COG1207	M
LFTS_00070	490.021399834942	-0.183557325165869	0.14914437346691	-1.23073583601593	0.218421680407096	0.39008354704888	882	Glyoxylase%2C beta-lactamase superfamily II	NA	K01069	 Carbohydrate metabolism	              Carbohydrate metabolism	               00620 Pyruvate metabolism	COG0491	R
LFTS_02200	930.825700983035	0.251661689743129	0.204728839600404	1.22924396110645	0.218980351020017	0.390800540298466	678	phage shock protein A (PspA) family protein	NA	K03969	NA	              Translation	               03010 Ribosome	COG1842	KT
LFTS_00278	400.669823001609	0.187845346245646	0.153212375657908	1.22604551648665	0.220181546983232	0.392662357102091	690	NAD(P)H-flavin reductase	NA	K00523	 Carbohydrate metabolism	              Carbohydrate metabolism	               00520 Amino sugar and nucleotide sugar metabolism	COG0543	HC
LFTS_02130	239.866424639411	0.233828036061751	0.190931847313533	1.22466754159549	0.2207005084346	0.393305708937933	495	Ribosomal protein S18 acetylase RimI	NA	K03789	NA	              Translation	               03010 Ribosome	COG0456	J
LFTS_01138	681.122089268639	0.230295561069168	0.188176883729296	1.22382492740428	0.221018278619445	0.393589857197665	1404	CRISPR-associated protein Cas7/Cse4/CasC%2C subtype I-E/ECOLI	NA	NA	NA	NA	NA	NA	NA
LFTS_00665	657.100987985772	-0.1796517709772	0.146923902759198	-1.22275387192539	0.221422672786579	0.39402774842336	909	cation diffusion facilitator family transporter	Cadmium/cobalt/zinc resistance	K13283	NA	              Cellular community - prokaryotes	               02024 Quorum sensing	COG0053	P
LFTS_00707	761.796986998506	0.178677575337498	0.146261108949194	1.2216342171969	0.221845982955626	0.394402617089337	243	Fe-S cluster biosynthesis and repair protein YggX	NA	NA	NA	NA	NA	NA	NA
LFTS_02402	778.249975686835	0.214772345079853	0.175847215656587	1.22135766709712	0.221950628040218	0.394402617089337	1092	rod shape determining protein RodA	NA	K05837	NA	              Glycan biosynthesis and metabolism	               00550 Peptidoglycan biosynthesis	COG0772	D
LFTS_00628	3324.86016749136	-0.157917253836939	0.129368039713211	-1.22068212664439	0.222206397605532	0.394575074605252	1380	oxygen-independent coproporphyrinogen-3 oxidase	NA	K02495	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00860 Porphyrin and chlorophyll metabolism	COG0635	H
LFTS_00357	98.6922683847832	0.293802504520702	0.24098399915154	1.21917847473328	0.222776459966313	0.395199349392166	1140	AcrB/AcrD/AcrF family protein	NA	K03296	NA	              Amino acid metabolism	               00260 Glycine, serine and threonine metabolism	COG0841	V
LFTS_02228	939.873118871738	0.234713258315666	0.192558936802013	1.21891646377854	0.222875900180136	0.395199349392166	963	hypothetical protein	NA	K07489	NA	              Overview	               01200 Carbon metabolism	COG3677	X
LFTS_01065	25.1708850877961	-0.450177335721861	0.369894170651623	-1.21704360717231	0.223587624877605	0.39604589910875	1137	ERF superfamily protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01220	1618.1546567812	-0.469228831432496	0.385618293765646	-1.21682202068365	0.223671939802367	0.39604589910875	1662	NAD(P)H-quinone oxidoreductase subunit 5	NADH dehydrogenase	K05577	 Energy metabolism	              Energy metabolism	               00190 Oxidative phosphorylation	COG1009	CP
LFTS_00787	477.862721720637	-0.237914290382732	0.195911109140213	-1.21439918045922	0.224595328228028	0.397397854786389	255	hypothetical protein	NA	K12569	 Cardiovascular diseases	              Cardiovascular diseases	               05410 Hypertrophic cardiomyopathy (HCM)	NA	
LFTS_01906	648.67486579605	0.212933821406076	0.175469640547879	1.21350805040245	0.224935638360722	0.397455211103218	1755	aspartyl-tRNA synthetase	NA	K01876	 Translation	              Translation	               00970 Aminoacyl-tRNA biosynthesis	COG0173;COG0017	J
LFTS_00142	1192.08284973117	0.166759704056278	0.137423043576015	1.2134770102369	0.224947498802183	0.397455211103218	243	TusA-related sulfurtransferase	NA	K04085	 Folding, sorting and degradation	              Folding, sorting and degradation	               04122 Sulfur relay system	COG0425	O
LFTS_02536	1321.11828293698	0.159306088630154	0.131370152687649	1.21265055547988	0.225263451327338	0.397547974967411	1113	3-isopropylmalate dehydrogenase	NA	K00052	 Amino acid metabolism; Overview; Carbohydrate metabolism	              Overview	               01210 2-Oxocarboxylic acid metabolism	COG0473	CE
LFTS_00236	1014.49279794094	0.168350437855299	0.13886079101344	1.21236842039165	0.225371383717303	0.397547974967411	228	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00450	1122.96214357018	-0.182512035586449	0.150576895214189	-1.21208526266153	0.225479744450543	0.397547974967411	1998	basic amino acid/polyamine antiporter%2C APA family	NA	K03294	NA	              Metabolism of terpenoids and polyketides	               00523 Polyketide sugar unit biosynthesis	COG0531	E
LFTS_02131	370.105179089779	0.222628309977049	0.183785353170892	1.2113495778417	0.225761455218124	0.397762563906631	531	YacP-like NYN domain protein	NA	K06962	NA	              Translation	               03010 Ribosome	COG3688	R
LFTS_01211	152.137370936176	0.285384137610576	0.23582346174678	1.2101600726946	0.226217475692391	0.398258020014306	573	putative transposase	NA	K07496	NA	              Signal transduction	               02020 Two-component system	COG0675	X
LFTS_02138	532.364006331369	-0.189509855398486	0.156648110160358	-1.20978066830482	0.226363066082146	0.398258020014306	1359	NADH dehydrogenase	NA	K03885	 Energy metabolism	              Energy metabolism	               00190 Oxidative phosphorylation	COG1252	C
LFTS_00489	550.722015317016	0.185475969234296	0.153413552548881	1.20899337869905	0.22666538919052	0.398507890755044	900	Glucose-1-phosphate thymidylyltransferase	Extracellular polysaccharide production and export	K00973	 Biosynthesis of other secondary metabolites; Metabolism of terpenoids and polyketides	              Metabolism of terpenoids and polyketides	               00523 Polyketide sugar unit biosynthesis	COG1209	M
LFTS_01957	2333.52503553859	-0.14752514725296	0.122221065604687	-1.20703535452813	0.227418528738614	0.399316852700984	1422	PAS domain S-box-containing protein	Nitrogenase genes	K02584	 Signal transduction	              Signal transduction	               02020 Two-component system	COG3604	KT
LFTS_02307	112.224457144908	-0.308331943693961	0.255461179514843	-1.20696202953234	0.22744676726653	0.399316852700984	2214	cellulose synthase subunit	Cellulose production	NA	NA	NA	NA	NA	NA
LFTS_01489	650.571623549432	0.168934287871136	0.140085113696365	1.20594032737341	0.227840499765798	0.399725816808592	1149	5-(carboxyamino)imidazole ribonucleotide synthase	NA	K01589	 Nucleotide metabolism	              Nucleotide metabolism	               00230 Purine metabolism	COG0026	F
LFTS_00998	70.9451902122664	0.338276768594211	0.280637897021301	1.20538520344077	0.228054630918867	0.399793880905476	636	Phosphoadenosine phosphosulfate reductase family protein	NA	K00390	 Energy metabolism	              Energy metabolism	               00920 Sulfur metabolism	COG0175	EH
LFTS_00185	36.6433524900285	-0.401837728376677	0.333473594371199	-1.205006138895	0.228200932021267	0.399793880905476	192	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00111	209.976520716863	-0.224524289267511	0.18657999918373	-1.20336740406144	0.228834175877938	0.400404659006808	2214	ATP-dependent DNA helicase DinG	NA	K03722	NA	              Glycan biosynthesis and metabolism	               00514 Other types of O-glycan biosynthesis	COG1199	L
LFTS_01240	292.328197014196	0.271927694594907	0.225990507850638	1.2032704257412	0.228871689641462	0.400404659006808	411	Phenazine biosynthesis-like protein	NA	K06998	 Cellular community - prokaryotes;NA	              Biosynthesis of other secondary metabolites	               00405 Phenazine biosynthesis	COG0384	R
LFTS_00128	1297.20115511184	-0.151693272425892	0.126130405534562	-1.20267013955113	0.229103993541528	0.400529203898902	2235	RNAse R	NA	K12573	 Folding, sorting and degradation	              Folding, sorting and degradation	               03018 RNA degradation	COG0557	K
LFTS_00071	562.152384941455	0.173019359080581	0.143994808378618	1.2015666469422	0.229531470283466	0.400994543306181	1086	hypothetical protein	NA	K07286	NA	              Carbohydrate metabolism	               00620 Pyruvate metabolism	COG3056	S
LFTS_02132	421.126672969992	0.21762774789976	0.181202666881814	1.2010184598536	0.229744040716862	0.401084048611039	1431	amino acid/polyamine/organocation transporter%2C APC superfamily	NA	K03294	NA	              Translation	               03010 Ribosome	COG0531	E
LFTS_00023	427.351207222199	-0.281271046388657	0.23494505306812	-1.19717798998349	0.231237186802845	0.40332733934392	993	NTE family protein	NA	K07001	NA	              Cell growth and death	               04112 Cell cycle - Caulobacter	COG1752	R
LFTS_02358	1174.63835818069	-0.180187345656186	0.150557058606354	-1.19680436987882	0.231382814628203	0.40332733934392	1254	acetylornithine/N-succinyldiaminopimelate aminotransferase	NA	K00818	 Overview; Amino acid metabolism	              Overview	               01210 2-Oxocarboxylic acid metabolism	COG0160;COG4992	E
LFTS_01102	40.7142260213185	0.389357404823955	0.325423553904446	1.19646350165017	0.231515733404575	0.40332733934392	1164	hypothetical protein	NA	K06871	NA	              Amino acid metabolism	               00350 Tyrosine metabolism	COG0641	O
LFTS_00818	1688.13154713526	-0.195351875357254	0.163426830652806	-1.19534763402633	0.23195123616089	0.403803062392137	1146	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00507	835.062097360483	0.3024926895387	0.253529991704878	1.19312388843848	0.232820857142447	0.404931943969872	1044	putative zinc-type alcohol dehydrogenase-like protein	NA	K13979	NA	              Carbohydrate metabolism	               00500 Starch and sucrose metabolism	COG1064	G
LFTS_00029	1439.88934270131	-0.145946313097395	0.122381691185947	-1.19255022285682	0.233045570393284	0.404931943969872	1107	diguanylate cyclase	NA	K13590	 Cell growth and death	              Cell growth and death	               04112 Cell cycle - Caulobacter	COG2199	T
LFTS_02254	1169.002434248	0.199266310252522	0.167107887397064	1.19244108316112	0.233088339429158	0.404931943969872	405	ribonuclease HI	NA	K03469	 Replication and repair	              Replication and repair	               03030 DNA replication	COG0328	L
LFTS_01778	1349.66335399467	-0.22854079565253	0.191931609389848	-1.19074078719531	0.233755360630789	0.405807141430267	966	GDP-L-fucose synthase	NA	K02377	 Carbohydrate metabolism	              Carbohydrate metabolism	               00051 Fructose and mannose metabolism	COG0451	M
LFTS_00147	2225.23913239997	-0.166812766001969	0.140328787656041	-1.18872804923565	0.23454669925117	0.406896786000286	1362	regulatory protein%2C Fis family	NA	K02481	NA	              Overview	               01230 Biosynthesis of amino acids	COG2204	T
LFTS_02504	1645.27982387889	0.218143133167522	0.183709278653369	1.18743666496631	0.23505542487988	0.407260902131525	453	large subunit ribosomal protein L9	NA	K02939	 Translation	              Translation	               03010 Ribosome	COG0359	J
LFTS_01123	198.045922393684	0.22132385777351	0.186399395205557	1.18736360453015	0.235084229508744	0.407260902131525	2061	type II and III secretion system protein	NA	K12282	NA	              Metabolism of terpenoids and polyketides	               00900 Terpenoid backbone biosynthesis	COG1450	U
LFTS_00808	2791.68695324447	0.17831693825502	0.150281314575805	1.18655428825833	0.235403475733869	0.407529972614484	270	SSU ribosomal protein S15P	NA	K02956	 Translation	              Translation	               03010 Ribosome	COG0184	J
LFTS_00811	1690.91438016583	-0.141732478457501	0.119667561852967	-1.18438511040816	0.236260651529505	0.408729283021816	1236	putative Zn-dependent peptidase	NA	K01412	NA	              Metabolism of cofactors and vitamins	               00770 Pantothenate and CoA biosynthesis	NA	
LFTS_01362	721.899012958758	0.159934869119271	0.135122037134349	1.18363275533103	0.236558468310881	0.408746872716086	801	5'-nucleotidase /3'-nucleotidase /exopolyphosphatase	NA	K03787	 Nucleotide metabolism; Metabolism of cofactors and vitamins	              Nucleotide metabolism	               00230 Purine metabolism	COG0496	L
LFTS_02226	440.551195118764	0.276010431864958	0.233214607948297	1.18350404502169	0.236609444354209	0.408746872716086	1101	three-Cys-motif partner protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00705	780.820014950694	0.17192369468125	0.145314596965207	1.18311372891475	0.23676407751857	0.408746872716086	3264	Superfamily II DNA or RNA helicase%2C SNF2 family	NA	K15192	NA	              Signal transduction	               02020 Two-component system	NA	
LFTS_02229	406.990572883004	-0.18227126144307	0.154370490060482	-1.18073902189244	0.23770641466176	0.410088929111127	1197	hypothetical protein	NA	K07404	 Carbohydrate metabolism; Overview	              Overview	               01200 Carbon metabolism	COG2706	G
LFTS_00235	168.107718670089	-0.268697954741635	0.228707110298123	-1.1748561485097	0.240052272012192	0.413848785174973	708	3-oxoacyl-[acyl-carrier protein] reductase	NA	K00059	 Lipid metabolism; Overview; Metabolism of cofactors and vitamins	              Overview	               01212 Fatty acid metabolism	COG1028	IQR
LFTS_00804	4381.5265005889	0.177079296799633	0.15093763378211	1.17319512942186	0.240717564777057	0.414695576061277	2625	bacterial translation initiation factor 2 (bIF-2)	NA	K02519	NA	              Translation	               03010 Ribosome	COG0532	J
LFTS_02058	195.786973722154	0.255686976843932	0.218014624839566	1.17279736179207	0.240877076360613	0.414695576061277	717	hypothetical protein	NA	K07289	NA	              Cell growth and death	               04112 Cell cycle - Caulobacter	COG2982	M
LFTS_01407	390.188107502077	0.197354195944185	0.16857563230814	1.17071603553852	0.241712937439461	0.415846617629412	1233	DNA repair exonuclease SbcCD nuclease subunit	NA	K03547	NA	              Transport and catabolism	               04144 Endocytosis	COG0420	L
LFTS_01493	452.47553432803	-0.194043602260954	0.165899766296129	-1.16964361429292	0.242144418005417	0.416150415033357	1452	GGDEF domain-containing protein%2C diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	Putative diguanylate cyclases (GGDEF domain-containing proteins)	K13590	 Cell growth and death	              Cell growth and death	               04112 Cell cycle - Caulobacter	COG2199	T
LFTS_01605	985.986614335912	0.180320657830651	0.154193339798658	1.16944517880026	0.242224316393109	0.416150415033357	522	putative OsmC-related protein	NA	K07397	NA	              Metabolism of cofactors and vitamins	               00780 Biotin metabolism	COG1765	R
LFTS_02199	1003.63175278688	0.254266513460896	0.217562715558272	1.16870444831708	0.242522729125003	0.416323982164925	657	hypothetical protein	NA	K09942	NA	              Carbohydrate metabolism	               00630 Glyoxylate and dicarboxylate metabolism	COG3330	S
LFTS_01036	29.860397749269	0.405695344914402	0.347233918572726	1.168363236466	0.242660277617448	0.416323982164925	363	hypothetical protein	NA	K09940	NA	              Carbohydrate metabolism	               00500 Starch and sucrose metabolism	COG3296	S
LFTS_00337	2972.82828673062	0.185083165008371	0.15854313848285	1.16739940169906	0.243049112641138	0.41670351312129	213	prokaryotic ubiquitin-like protein Pup	NA	K13570	NA	              Folding, sorting and degradation	               03050 Proteasome	NA	
LFTS_01125	9.3051030692371	0.502823941195776	0.430936626173041	1.16681644273576	0.243284505297159	0.416819627959158	537	hypothetical protein	NA	K02456	 Cellular community - prokaryotes; Membrane transport	              Membrane transport	               03070 Bacterial secretion system	COG2165	NUW
LFTS_01270	36.0321510421674	-0.384178884788969	0.330070532176882	-1.16392966756297	0.244452515494289	0.418532337134162	372	Acetyltransferase (GNAT) domain-containing protein	NA	K03789	NA	              Translation	               03010 Ribosome	COG0456	J
LFTS_01150	207.730742803227	-0.215521064439333	0.18528889483127	-1.16316233973759	0.244763643097353	0.41877661165865	1257	HDIG domain-containing protein	NA	K07814	NA	              Signal transduction	               02020 Two-component system	COG3437	T
LFTS_01867	628.294193884164	0.210662063119602	0.181221148943449	1.16245848979437	0.245049276679725	0.418976961365747	1377	two-component system%2C NtrC family%2C nitrogen regulation response regulator GlnG	Nitrate/nitrite regulation	K07714	 Signal transduction	              Signal transduction	               02020 Two-component system	COG2204	T
LFTS_01417	139.672285723291	0.23868088062992	0.205420882985441	1.16191147249054	0.245271426522693	0.41906856792812	96	ORF6N domain-containing protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00599	174.472948676078	-0.241236836392323	0.208574215544572	-1.15659951429026	0.247436020804932	0.422476612445783	756	cell division protein FtsW	NA	K03588	 Cell growth and death	              Cell growth and death	               04112 Cell cycle - Caulobacter	COG0772	D
LFTS_01755	47.2970513730092	-0.391032158413238	0.339298535141061	-1.15247228594921	0.249127051783047	0.425071963440395	510	Ni%2CFe-hydrogenase III small subunit	NA	K15832	NA	              Energy metabolism	               00190 Oxidative phosphorylation	COG3260	C
LFTS_00234	258.639107858948	-0.221030392839078	0.192113937663005	-1.1505172166467	0.249930907292789	0.426151053175497	303	flagellar biosynthesis protein	NA	K04061	NA	              Nucleotide metabolism	               00230 Purine metabolism	COG2257	U
LFTS_01499	558.321632932777	0.189594876836387	0.165262503434878	1.14723468963482	0.251284638137383	0.428165600006535	942	Tetratricopeptide repeat-containing protein	NA	K03353	 Cell growth and death; Endocrine system; Folding, sorting and degradation; Infectious diseases	              Folding, sorting and degradation	               04120 Ubiquitin mediated proteolysis	NA	
LFTS_01466	8.1443002731101	-0.497379183372701	0.433914528226772	-1.14626072882437	0.251687286878869	0.428308534227474	615	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00323	272.574208280337	0.245813695875959	0.214460002683938	1.14619832509388	0.25171310076683	0.428308534227474	270	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_02534	1422.92017326837	0.168987894063471	0.147612302227807	1.144809013294	0.252288280827011	0.428993615688063	951	quinolinate synthetase	NA	K03517	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00760 Nicotinate and nicotinamide metabolism	COG0379	H
LFTS_00333	3070.25561860362	-0.175594966831016	0.153529563164597	-1.14372087832207	0.252739411935895	0.429466970657987	861	Regulator of protease activity HflC%2C stomatin/prohibitin superfamily	NA	K04087	NA	              Folding, sorting and degradation	               03050 Proteasome	COG0330	O
LFTS_02156	475.573703648658	-0.172204141614517	0.150730661597648	-1.14246258716882	0.253261788734926	0.430020054646816	1149	hypothetical protein	NA	K06076	NA	              Translation	               03008 Ribosome biogenesis in eukaryotes	COG2067	I
LFTS_01149	1710.58027615247	-0.195581079033464	0.171246317039595	-1.14210385609778	0.253410852798707	0.430020054646816	873	Nucleotidyl transferase AbiEii toxin%2C Type IV TA system	NA	K09144	NA	              Infectious diseases	               05132 Salmonella infection	COG2253	V
LFTS_01486	498.974824929334	0.202236008461662	0.177456928566116	1.13963433321971	0.254438675357159	0.431469677310981	261	(2Fe-2S) ferredoxin	NA	K05587	 Energy metabolism	              Energy metabolism	               00190 Oxidative phosphorylation	COG1894	C
LFTS_00179	700.534797480722	-0.191071552779544	0.167830831206799	-1.13847706887722	0.25492132880283	0.431993471986254	345	Rhodanese-related sulfurtransferase	NA	K02439	 Energy metabolism	              Energy metabolism	               00920 Sulfur metabolism	COG0607	P
LFTS_00528	116.249123621562	-0.267414381747975	0.235252514124437	-1.13671211014785	0.255658655111485	0.432947831476261	1320	Glycosyltransferase involved in cell wall bisynthesis	Extracellular polysaccharide production and export	K08256	NA	              Cell motility	               02040 Flagellar assembly	COG0438	M
LFTS_00899	1141.95265843984	-0.147512641558317	0.129977312221804	-1.13491069354157	0.256412738950494	0.433727322615576	1344	TolB protein	NA	K03641	NA	              Metabolism of cofactors and vitamins	               00790 Folate biosynthesis	COG0823	U
LFTS_01753	32.128371281114	-0.380897585832557	0.335657914654201	-1.13477909860985	0.256467885858768	0.433727322615576	1458	hydrogenase-4 component F	NA	K12141	NA	              Amino acid metabolism	               00260 Glycine, serine and threonine metabolism	COG0651	CP
LFTS_02455	5978.94673625553	0.136742622166606	0.121512863600856	1.12533453754967	0.260447299561381	0.440157706804618	306	Pyruvate:ferredoxin oxidoreductase%2C delta subunit	Reductive TCA cycle carbon dioxide fixation	K00171	 Carbohydrate metabolism; Overview; Energy metabolism; Xenobiotics biodegradation and metabolism	              Overview	               01200 Carbon metabolism	COG1144	C
LFTS_01200	29.6605473524916	-0.401642852933162	0.358343558956842	-1.12083179087233	0.262359469239653	0.443088071012077	339	nitrogen regulatory protein P-II family protein	Nitrate/nitrite regulation	K02589	NA	              Translation	               00970 Aminoacyl-tRNA biosynthesis	COG0347	TE
LFTS_01160	20.2082211763943	0.442088284283515	0.395900202008902	1.11666597299077	0.264137171962001	0.445787514933833	1503	Molybdate transporter of MFS superfamily protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01177	3.88262911334038	-0.468309125095043	0.419570089001146	-1.11616422946147	0.264351842914472	0.445847138049781	306	nitrogen fixation protein NifZ	Nitrogenase genes	K02597	NA	              Carbohydrate metabolism	               00051 Fructose and mannose metabolism	NA	
LFTS_00153	697.495776210307	0.164479900212654	0.147819239247137	1.11270969225908	0.265833131531234	0.448041467787557	1656	peptide chain release factor 3	NA	K02837	NA	              Replication and repair	               03440 Homologous recombination	COG0480	J
LFTS_00686	2667.89679975472	0.167529428060393	0.150871085649375	1.11041441333385	0.266820490086767	0.449400906745056	2727	protein translocase subunit secA	NA	K03070	 Cellular community - prokaryotes; Folding, sorting and degradation; Membrane transport	              Folding, sorting and degradation	               03060 Protein export	COG0653	U
LFTS_01021	218.820251938501	0.241082388977212	0.217439289385804	1.10873425708018	0.267544838961918	0.450315822382755	1344	exodeoxyribonuclease-5	NA	K01144	NA	              Metabolism of other amino acids	               00410 beta-Alanine metabolism	NA	
LFTS_00284	82.751596940256	0.291159813112627	0.262830948014545	1.10778359744955	0.267955285556803	0.450701515489995	498	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00403	2938.72444608296	-0.15952533589325	0.144454054012627	-1.10433270276586	0.269448841728142	0.452907248503152	1329	seryl-tRNA synthetase	NA	K01875	 Translation	              Translation	               00970 Aminoacyl-tRNA biosynthesis	COG0172	J
LFTS_01608	1158.74992719827	-0.144045482984967	0.130632255810414	-1.10267928921032	0.270166463881652	0.453806641357965	696	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01290	2516.20445033521	0.200652658604801	0.182602751688059	1.09884794588187	0.271834394965032	0.456300003972364	2346	Beta-barrel assembly machine subunit BamA	NA	K07277	NA	              Glycan biosynthesis and metabolism	               00540 Lipopolysaccharide biosynthesis	COG4775	M
LFTS_00056	601.660871489965	0.160362347750956	0.146307409368481	1.09606443339501	0.27305057798726	0.45795109038648	1737	peptide/nickel transport system substrate-binding protein	NA	K02035	 Cellular community - prokaryotes	              Cellular community - prokaryotes	               02024 Quorum sensing	COG0747	E
LFTS_01351	226.558973721292	-0.236134974393228	0.21549998255875	-1.09575403018352	0.273186430829907	0.45795109038648	426	Cytochrome C oxidase%2C cbb3-type%2C subunit III	Cytochrome cbb3 oxidase	K00406	 Energy metabolism; Signal transduction	              Energy metabolism	               00190 Oxidative phosphorylation	COG2010	C
LFTS_00124	466.333414808815	0.166696484001986	0.152433837468967	1.0935661449573	0.274145304216223	0.45895003006622	486	hypothetical protein	NA	K09928	NA	              Signal transduction	               04014 Ras signaling pathway	COG3216	S
LFTS_01420	138.16073503437	0.246417246123711	0.225336586399413	1.09355187304973	0.274151566632477	0.45895003006622	177	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01872	222.801825297953	0.198523363474645	0.182227967736259	1.08942313268823	0.275967334892719	0.461499918315502	621	glycerol-3-phosphate acyltransferase PlsY	NA	K08591	 Lipid metabolism	              Lipid metabolism	               00561 Glycerolipid metabolism	COG0344	I
LFTS_00851	57136.3596060233	-0.191118860081607	0.175459992542563	-1.08924466091748	0.276046009064824	0.461499918315502	1626	chaperonin GroEL	Chaperones	K04077	 Aging; Endocrine and metabolic diseases; Folding, sorting and degradation; Infectious diseases	              Folding, sorting and degradation	               03018 RNA degradation	COG0459	O
LFTS_01725	40.4009911127163	-0.365778667451374	0.336094475279742	-1.08832097625801	0.276453433457769	0.461870454016138	315	Phage integrase family protein	NA	K03733	NA	              Replication and repair	               03030 DNA replication	COG0582	LX
LFTS_02298	542.636445187087	0.165229828237287	0.152101968503085	1.08630959785334	0.277342042130843	0.463043866176813	1674	2-octaprenylphenol hydroxylase	NA	K03688	NA	              Membrane transport	               02010 ABC transporters	COG0661	HT
LFTS_00733	1168.0492699682	0.169908032102239	0.156478312283594	1.08582479976079	0.277556512195342	0.463090932427934	2874	diguanylate cyclase (GGDEF) domain-containing protein	NA	K14051	 Cellular community - prokaryotes	              Cellular community - prokaryotes	               02024 Quorum sensing	COG2199;COG2200;COG2202	T
LFTS_00826	872.925872233463	-0.157573991617017	0.14521383174851	-1.08511695972538	0.277869856708159	0.463302792606628	2142	ATP-dependent DNA helicase RecG	NA	K03655	 Replication and repair	              Replication and repair	               03440 Homologous recombination	COG1200	L
LFTS_01807	1078.17057527176	0.197031741536543	0.18172358342723	1.08423869825043	0.278258977577497	0.463632617439112	444	Transposase (or an inactivated derivative)	NA	K07493	NA	              Overview	               01200 Carbon metabolism	COG3328	X
LFTS_02159	2481.2543086675	-0.14634670838745	0.135027500911258	-1.08382890448095	0.278440666869104	0.463632617439112	231	acyl carrier protein	NA	K02078	 Lipid metabolism	              Lipid metabolism	               00061 Fatty acid biosynthesis	COG0236	IQ
LFTS_01556	707.484016259346	-0.160841860110022	0.148660373902833	-1.08194171646004	0.279278426778966	0.464716311226579	1416	fumarase%2C class II	Reductive TCA cycle carbon dioxide fixation	K01679	 Carbohydrate metabolism; Overview; Cancers; Energy metabolism	              Overview	               01200 Carbon metabolism	COG0114	C
LFTS_01456	376.783112062121	-0.216748444073502	0.20043127202886	-1.0814103102748	0.279514637389171	0.464798253210353	426	transcriptional regulator%2C BadM/Rrf2 family	NA	K13643	NA	              Signal transduction	               02020 Two-component system	COG1959	K
LFTS_00860	544.832462064043	0.186448010133454	0.17289108468154	1.07841309733747	0.280849444642007	0.466705694772746	735	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00317	257.148376198097	0.196282741391698	0.182376019369982	1.07625301873435	0.281814113905022	0.467995916611814	762	PLD-like domain-containing protein	NA	K06131	 Lipid metabolism	              Lipid metabolism	               00564 Glycerophospholipid metabolism	COG1502	I
LFTS_00241	1760.1433394511	0.167687090643622	0.15587572324387	1.07577425883871	0.282028227177038	0.46803883361957	1185	LL-diaminopimelate aminotransferase apoenzyme	NA	K08969	 Amino acid metabolism	              Amino acid metabolism	               00270 Cysteine and methionine metabolism	COG0436	E
LFTS_00861	444.912336032323	-0.201894603229284	0.187943025693079	-1.07423301548304	0.282718258502836	0.468870974408305	543	phosphatidylglycerophosphatase A	NA	K01095	 Lipid metabolism	              Lipid metabolism	               00564 Glycerophospholipid metabolism	COG1267	I
LFTS_00997	36.0385463757889	-0.348784580424698	0.325557225063238	-1.07134645946484	0.2840136771099	0.470528258204143	531	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01945	578.962968052831	0.238118483554152	0.222298999761858	1.07116309029389	0.284096104410466	0.470528258204143	918	NAD+ kinase	NA	K00858	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00760 Nicotinate and nicotinamide metabolism	COG0061	F
LFTS_02203	153.916726145723	-0.226850301571295	0.211907517840672	-1.07051559039948	0.284387295242958	0.470696948051927	582	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00778	424.12211974474	0.163978448437432	0.153582709448054	1.06768821195262	0.285661177580158	0.472490810022802	1176	SAM-dependent methyltransferase	NA	K06969	NA	              Translation	               03010 Ribosome	COG1092	J
LFTS_00465	197.689964833854	0.217267952106071	0.203913216593272	1.06549225075212	0.286653230495963	0.473816443492662	447	hypothetical protein	NA	K06929	NA	              Lipid metabolism	               00564 Glycerophospholipid metabolism	COG1832	R
LFTS_01086	9.91898406418549	-0.455858749648998	0.428421810110537	-1.06404188323508	0.287309726409385	0.474507602597505	333	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01839	126.462886968118	-0.268255076239384	0.252184518475117	-1.06372539385622	0.287453117261401	0.474507602597505	759	Regulator of protease activity HflC%2C stomatin/prohibitin superfamily	NA	K15932	 Metabolism of terpenoids and polyketides	              Metabolism of terpenoids and polyketides	               01057 Biosynthesis of type II polyketide products	NA	
LFTS_00523	96.8376227331301	-0.272202928733853	0.256003579562746	-1.06327782290691	0.287655979249046	0.474527381826893	789	methyltransferase%2C FkbM family	NA	NA	NA	NA	NA	NA	NA
LFTS_01575	1618.26820823889	-0.126831084178249	0.119935704822454	-1.05749229861118	0.290286967585901	0.478550000940683	2220	glycyl-tRNA synthetase beta chain	NA	K01879	 Translation	              Translation	               00970 Aminoacyl-tRNA biosynthesis	COG0751	J
LFTS_01273	27.0043629398608	-0.383110191772064	0.362480182856086	-1.0569134807686	0.290551075423407	0.478667974488132	159	Transposase IS200 like protein	NA	K07491	NA	              Translation	               03010 Ribosome	COG1943	X
LFTS_00395	3133.27460535722	0.165673722664746	0.156859558505591	1.05619143801709	0.290880761675148	0.478893757300938	1431	zinc protease	NA	K07263	NA	              Carbohydrate metabolism	               00520 Amino sugar and nucleotide sugar metabolism	COG0612	R
LFTS_02075	454.287439783748	-0.167744345799024	0.159213396806737	-1.0535818540612	0.292074400605823	0.480540674987476	834	putative membrane-anchored protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00467	724.273382977387	0.153172075176285	0.145586798885506	1.05210140169882	0.292753029126982	0.481338644450844	594	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00822	975.921915942963	0.164336956628613	0.15652512677894	1.04990783275778	0.293760490008128	0.482675861308795	1377	ubiquinol-cytochrome c reductase cytochrome b subunit	Cytochrome b/c1	K00412	 Circulatory system; Endocrine and metabolic diseases; Energy metabolism; Signal transduction; Neurodegenerative diseases	              Energy metabolism	               00190 Oxidative phosphorylation	COG1290	C
LFTS_02283	773.35131088797	0.170465519674105	0.162755838788611	1.04736961170104	0.294929141547301	0.484275988036057	1260	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01333	976.391227878597	-0.141210646566268	0.135225399425596	-1.04426126427502	0.296364529166456	0.486311696044759	1278	phosphoribosylamine--glycine ligase	NA	K01945	 Nucleotide metabolism	              Nucleotide metabolism	               00230 Purine metabolism	COG0151	F
LFTS_01702	304.027660751072	0.177353172755162	0.169925612211883	1.04371065930907	0.29661927668113	0.486408655560218	1245	2-polyprenyl-6-methoxyphenol hydroxylase	NA	K05712	 Amino acid metabolism; Overview	              Overview	               01220 Degradation of aromatic compounds	COG0654	HC
LFTS_01563	1092.97473407371	0.136718757825912	0.131049527470121	1.04326021211396	0.296827793265007	0.486429725812002	1434	DNA recombination protein RmuC	NA	K09760	NA	              Metabolism of cofactors and vitamins	               00860 Porphyrin and chlorophyll metabolism	COG1322	L
LFTS_00436	70.1008568404276	-0.282922117198997	0.271915874524362	-1.04047664629322	0.298118508535788	0.488223064703536	216	putative nuclease of the RNAse H fold%2C HicB family	NA	NA	NA	NA	NA	NA	NA
LFTS_01498	71.7598791211866	-0.272416687949088	0.261934547819339	-1.0400181656716	0.298331461079483	0.488250172642262	177	Aldo/keto reductase family protein	NA	K05882	NA	              Folding, sorting and degradation	               04120 Ubiquitin mediated proteolysis	NA	
LFTS_02184	761.85614096576	0.222955662454129	0.214608377830035	1.03889542760863	0.298853373144303	0.488635311341683	1458	TldD protein	NA	K03568	NA	              Metabolism of terpenoids and polyketides	               00906 Carotenoid biosynthesis	COG0312	R
LFTS_02162	711.600858363694	0.149228130142148	0.143672815257211	1.03866643021501	0.298959898853862	0.488635311341683	1026	3-oxoacyl-[acyl-carrier-protein] synthase-3	NA	K00648	 Overview; Lipid metabolism	              Overview	               01212 Fatty acid metabolism	COG0332	I
LFTS_02300	102.169928058592	-0.25071283536867	0.241626127055801	-1.03760648082055	0.29945329946649	0.48912017245315	678	undecaprenyl-diphosphatase	NA	K01096	 Lipid metabolism	              Lipid metabolism	               00564 Glycerophospholipid metabolism	COG0671	I
LFTS_00655	1041.61748261657	0.195065853663673	0.188313346306854	1.03585782680435	0.300268475037748	0.49012963161119	1362	two-component system%2C OmpR family%2C phosphate regulon sensor histidine kinase PhoR	NA	K07652	 Signal transduction	              Signal transduction	               02020 Two-component system	COG5002	T
LFTS_00035	468.549863500141	0.197461262964466	0.190761093058867	1.03512335664554	0.300611306044168	0.490367261696721	1158	S-adenosylmethionine:tRNA ribosyltransferase-isomerase	NA	K07568	NA	              Cellular community - prokaryotes	               02024 Quorum sensing	COG0809	J
LFTS_00097	712.353198981967	-0.190088204064659	0.183731927954219	-1.034595381332	0.300857911871051	0.490447717318972	1011	peptide/nickel transport system ATP-binding protein	NA	K02031	 Cellular community - prokaryotes	              Cellular community - prokaryotes	               02024 Quorum sensing	COG0444;COG1123	EPO
LFTS_01710	378.752196725496	-0.184245634707928	0.179474904677138	-1.02658159946858	0.304617522093129	0.496251087761152	1491	Tetratricopeptide repeat protein	NA	K12284	NA	              Carbohydrate metabolism	               00520 Amino sugar and nucleotide sugar metabolism	NA	
LFTS_02235	488.544850015072	0.150229029237371	0.146421679284473	1.02600263821248	0.304890340514753	0.496370259672348	1242	HD domain-containing protein	NA	K07814	NA	              Carbohydrate metabolism	               00500 Starch and sucrose metabolism	COG3437	T
LFTS_01533	1129.16760467497	0.175462368688022	0.171205073106964	1.02486664386632	0.305426115447289	0.496917096205471	1098	chorismate mutase / prephenate dehydratase	NA	K14170	 Overview; Amino acid metabolism	              Overview	               01230 Biosynthesis of amino acids	COG1605;COG0077	E
LFTS_01043	23.7323028447579	0.385712232696423	0.376557047695365	1.02431287651391	0.305687517908517	0.497017115448379	396	hypothetical protein	NA	K15151	NA	              Folding, sorting and degradation	               03018 RNA degradation	NA	
LFTS_01142	30.7552120334461	-0.386424180956886	0.378227039030286	-1.02167254342158	0.30693591037777	0.498720701437344	1722	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_02470	478.696365248691	0.154107796320096	0.151046393890164	1.02026796106207	0.307601393853332	0.499369292998793	762	mannose-1-phosphate guanylyltransferase / phosphomannomutase	NA	K00966	 Carbohydrate metabolism	              Carbohydrate metabolism	               00051 Fructose and mannose metabolism	COG1208	JM
LFTS_01255	103.912956459661	0.22993459536592	0.225483631794261	1.01973963048334	0.307851961006223	0.499369292998793	1182	serine/threonine-protein kinase HipA	NA	K07154	NA	              Overview	               01210 2-Oxocarboxylic acid metabolism	COG3550	T
LFTS_00492	693.248079903231	-0.15443635574289	0.151530309207067	-1.01917798855575	0.308118474539282	0.499369292998793	951	Sel1 repeat-containing protein	Extracellular polysaccharide production and export	K07126	NA	              Translation	               03010 Ribosome	COG0790	T
LFTS_01398	303.305619177992	-0.182863470313409	0.179429962390033	-1.01913564422375	0.308138574199577	0.499369292998793	1533	MFS transporter%2C DHA2 family%2C multidrug resistance protein	NA	K03446	NA	              Membrane transport	               03070 Bacterial secretion system	COG0477	GEPR
LFTS_00627	1485.88087641559	-0.161099331544276	0.158161279677818	-1.01857630307774	0.308404159073778	0.499463773375076	1071	uroporphyrinogen decarboxylase	NA	K01599	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00860 Porphyrin and chlorophyll metabolism	COG0407	H
LFTS_01399	194.361717432031	-0.245417536992294	0.241038636718578	-1.01816679820849	0.308598695053949	0.499463773375076	333	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01054	159.609321781775	0.206573119300863	0.202992220983662	1.01764056917969	0.308848800153337	0.499543342343003	1623	general secretion pathway protein D	NA	K02453	 Cellular community - prokaryotes; Membrane transport	              Membrane transport	               03070 Bacterial secretion system	COG1450	U
LFTS_02487	282.23119384269	-0.193045381286809	0.189960781248032	-1.01623808882292	0.309516022592387	0.500102607385092	306	hypothetical protein	NA	K07090	NA	              Overview	               01200 Carbon metabolism	COG0730	S
LFTS_01926	132.868258176875	0.256577183823099	0.252519645998071	1.01606820653098	0.309596907789886	0.500102607385092	1215	putative arabinose efflux permease%2C MFS family	NA	K03535	NA	              Signal transduction	               02020 Two-component system	COG0477	GEPR
LFTS_00788	994.615848942887	-0.131969173805183	0.130046515834932	-1.01478438663202	0.310208617950402	0.500509939024122	873	shikimate dehydrogenase	NA	K00014	 Overview; Amino acid metabolism	              Overview	               01230 Biosynthesis of amino acids	COG0169	E
LFTS_02230	46.3256659458734	0.338598012067074	0.333694716612491	1.01469395591383	0.310251736136835	0.500509939024122	285	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00638	44.5943918394039	0.314254330137403	0.310093712869836	1.01341728998328	0.310860884260765	0.501167417815993	408	PaaX-like protein	NA	K02616	NA	              Replication and repair	               03030 DNA replication	COG3327	K
LFTS_01268	428.090464402777	-0.175599297523694	0.17345029141185	-1.01238975209757	0.311351736279302	0.501633451970411	489	hypothetical protein	NA	K06142	NA	              Membrane transport	               03070 Bacterial secretion system	COG2825	MO
LFTS_01251	27.7566478355358	-0.379260126093097	0.375914192473953	-1.00890079088827	0.313022215877849	0.503998205098661	681	WYL domain-containing protein	NA	K13572	NA	              Overview	               01210 2-Oxocarboxylic acid metabolism	COG2378	K
LFTS_02431	685.637696937646	-0.16161424225343	0.160617594203465	-1.0062050988555	0.314316919931381	0.505755251099944	309	nitrite reductase (NADH) small subunit	Nitrite uptake & assimilation to ammonia	K00363	 Energy metabolism	              Energy metabolism	               00910 Nitrogen metabolism	COG2146	PQ
LFTS_01815	369.143115710793	-0.231797114921335	0.230704987662729	-1.00473386930066	0.315025014721202	0.506366639974543	1254	Glycosyltransferase involved in cell wall bisynthesis	Lipopolysaccharide synthesis	K13668	NA	              Membrane transport	               02010 ABC transporters	COG0438	M
LFTS_02154	967.771129082403	0.128720272172721	0.128134779145627	1.00456935291884	0.315104260676033	0.506366639974543	1053	phosphoribosylformylglycinamidine cyclo-ligase	NA	K01933	 Nucleotide metabolism	              Nucleotide metabolism	               00230 Purine metabolism	COG0150	F
LFTS_00449	449.367757356698	-0.172283000919759	0.171612740508369	-1.00390565647635	0.315424089857262	0.506553157225551	1599	Signal transduction histidine kinase	NA	K00936	NA	              Nucleotide metabolism	               00230 Purine metabolism	NA	
LFTS_00840	692.048678617339	0.169856178618074	0.169571082051213	1.00168128057811	0.316497550483091	0.507648749200893	297	integration host factor subunit beta	NA	K05788	NA	              Folding, sorting and degradation	               03060 Protein export	COG0776	L
LFTS_01414	441.875490740691	0.173166347628133	0.172982672026041	1.00106181503581	0.316796924366	0.507648749200893	1221	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01581	3878.76774359364	-0.175140202359628	0.17497593509992	-1.00093879915323	0.31685639729972	0.507648749200893	411	CBS domain-containing protein	NA	K07182	NA	              Glycan biosynthesis and metabolism	               00550 Peptidoglycan biosynthesis	COG2905	T
LFTS_00100	810.672469760429	-0.1634884615391	0.163357641434103	-1.00080082023619	0.316923112936358	0.507648749200893	1059	hypothetical protein	NA	K01186	 Lipid metabolism; Glycan biosynthesis and metabolism; Transport and catabolism	              Lipid metabolism	               00600 Sphingolipid metabolism	COG4409	GM
LFTS_02180	652.832649170319	0.149126441536783	0.149080410089758	1.00030876925411	0.317161104691777	0.507702837259341	1386	DNA repair protein RadA/Sms	NA	K04485	NA	              Amino acid metabolism	               00330 Arginine and proline metabolism	COG1066	O
LFTS_02155	526.703157346131	0.195164016371564	0.195289585705205	0.999357009575361	0.317621777620299	0.507814315430931	1065	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00720	2024.21441450214	-0.140683477710148	0.140825626022287	-0.998990607631901	0.317799241205565	0.507814315430931	1029	type II secretion system protein N	NA	K07289	NA	              Metabolism of cofactors and vitamins	               00760 Nicotinate and nicotinamide metabolism	COG2982	M
LFTS_00953	547.340113609164	0.194218173865771	0.194432216891952	0.998899138066713	0.317843553825635	0.507814315430931	540	adenosylcobinamide kinase /adenosylcobinamide-phosphate guanylyltransferase	NA	K02231	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00860 Porphyrin and chlorophyll metabolism	COG2087	H
LFTS_01580	615.935537683429	-0.151285991250383	0.151639000779509	-0.997672039994252	0.318438415535823	0.508437958267217	1143	8-amino-7-oxononanoate synthase	NA	K00652	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00780 Biotin metabolism	COG0156	H
LFTS_01188	44.2764944352926	-0.302636621006347	0.303794659862111	-0.996188086860085	0.319158766622531	0.509261035830302	1191	homocitrate synthase NifV	NA	K02594	 Carbohydrate metabolism	              Carbohydrate metabolism	               00620 Pyruvate metabolism	COG0119	E
LFTS_00745	59.9744511406287	-0.283796535599973	0.28533122825643	-0.994621364559939	0.319920452602952	0.510148970603553	618	repressor LexA	NA	K01356	NA	              Overview	               01200 Carbon metabolism	COG1974	KT
LFTS_00807	1047.58388585974	-0.173340514428188	0.175306058391887	-0.98878792905545	0.322766911353004	0.513964033086185	978	tRNA pseudouridine55 synthase	NA	K03177	NA	              Translation	               03010 Ribosome	COG0130	J
LFTS_01129	45.3050027333566	0.32589529115246	0.329602768374271	0.988751680575688	0.322784650488197	0.513964033086185	495	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_02434	717.904186411808	-0.192202246314031	0.194449961693164	-0.988440648897222	0.322936888052806	0.513964033086185	696	NAD(P)-dependent dehydrogenase%2C short-chain alcohol dehydrogenase family	NA	NA	NA	NA	NA	NA	NA
LFTS_01607	2959.45090944008	0.116337447880321	0.117749852575479	0.988005040649607	0.323150179553188	0.513964033086185	2196	hypothetical protein	NA	K12284	NA	              Carbohydrate metabolism	               00520 Amino sugar and nucleotide sugar metabolism	NA	
LFTS_00589	534.307938705789	-0.18216840913791	0.184476255399312	-0.987489738143232	0.323402611151362	0.513964033086185	543	hypothetical protein	Quorum sensing	K07782	 Cellular community - prokaryotes; Signal transduction	              Signal transduction	               02020 Two-component system	COG2771;COG2197	KTK
LFTS_00593	291.757863193775	0.174021404400695	0.176280959108681	0.987182082969077	0.323553383660451	0.513964033086185	276	hypothetical protein	NA	K00127	 Carbohydrate metabolism; Energy metabolism; Overview	              Overview	               01200 Carbon metabolism	COG2864	C
LFTS_01030	123.958489786257	0.220100970020746	0.22312551836325	0.986444632757872	0.323914972195135	0.514204084682582	663	Uracil DNA glycosylase superfamily protein	NA	K02334	NA	              Overview	               01210 2-Oxocarboxylic acid metabolism	COG1573	L
LFTS_01511	3375.02607922664	0.162663482603132	0.165027201180873	0.985676794123473	0.324291740484337	0.514204084682582	1608	D-3-phosphoglycerate dehydrogenase	NA	K00058	 Energy metabolism; Overview; Amino acid metabolism	              Overview	               01200 Carbon metabolism	COG0111	HR
LFTS_02260	1381.107515352	0.164141932595185	0.166538590180858	0.985608995590328	0.324325022036319	0.514204084682582	198	SSU ribosomal protein S21P	NA	K02970	 Translation	              Translation	               03010 Ribosome	COG0828	J
LFTS_02095	1065.16388949751	0.144775272051802	0.147074780422422	0.984365039580438	0.324936061071121	0.514844517414153	441	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01879	478.306370272366	0.16241446282352	0.165318462589132	0.982433905323515	0.325886129667012	0.516020967103307	1059	D-beta-D-heptose 7-phosphate kinase / D-beta-D-heptose 1-phosphate adenosyltransferase	NA	K03272	 Glycan biosynthesis and metabolism	              Glycan biosynthesis and metabolism	               00540 Lipopolysaccharide biosynthesis	COG2870	M
LFTS_01659	1361.47433941493	-0.178555646875726	0.182179326895204	-0.980109268810932	0.327032184384155	0.517506053710382	306	small subunit ribosomal protein S10	NA	K02946	 Translation	              Translation	               03010 Ribosome	COG0051	J
LFTS_01567	1387.26910786854	-0.216933781932497	0.221536965062523	-0.979221602459315	0.327470497006477	0.517870009897011	666	tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like protein	NA	K02609	 Amino acid metabolism	              Amino acid metabolism	               00360 Phenylalanine metabolism	COG3396	Q
LFTS_01950	2202.7994044424	0.138721037768433	0.142536581843936	0.973231124065536	0.330438445274625	0.522231389035421	795	tryptophan synthase%2C alpha chain	NA	K01695	 Overview; Amino acid metabolism	              Overview	               01230 Biosynthesis of amino acids	COG0159	E
LFTS_00522	1.84611811949931	-0.34307769660954	0.352706892486399	-0.972699155922418	0.330702844894714	0.522317199751117	147	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01859	175.778683917922	0.207345111645564	0.213590405481681	0.970760419588922	0.331667596740606	0.523508346347395	795	3%2C4-dihydroxyphenylacetate 2%2C3-dioxygenase	NA	K15777	 Biosynthesis of other secondary metabolites	              Biosynthesis of other secondary metabolites	               00965 Betalain biosynthesis	NA	
LFTS_01882	355.27226970904	0.176443585812116	0.18190930036458	0.969953627761141	0.332069607135378	0.523810306686898	1980	Glucoamylase (glucan-1%2C4-alpha-glucosidase)%2C GH15 family	NA	K01178	 Carbohydrate metabolism	              Carbohydrate metabolism	               00500 Starch and sucrose metabolism	COG3387	G
LFTS_00110	74.0844564792195	0.29658061788749	0.306030545085514	0.969120967335521	0.332484837419028	0.524016450273479	645	putative amidophosphoribosyltransferases	NA	K02242	NA	              Glycan biosynthesis and metabolism	               00514 Other types of O-glycan biosynthesis	COG1040	R
LFTS_00614	791.003989084078	0.188278739596507	0.194332922979567	0.968846331901796	0.332621865861444	0.524016450273479	600	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00367	657.717447167116	-0.168364877465648	0.173873354572562	-0.968319026682061	0.332885065279601	0.524098969148251	1275	HD domain-containing protein	NA	K07814	NA	              Carbohydrate metabolism	               00500 Starch and sucrose metabolism	COG3437	T
LFTS_01619	1457.08887617338	-0.134428417272036	0.139133429582105	-0.966183451926684	0.333952391831072	0.525446611450661	3213	heavy metal efflux pump%2C CzcA family	Cadmium/cobalt/zinc resistance	K03296	NA	              Nucleotide metabolism	               00230 Purine metabolism	COG0841	V
LFTS_00976	148.955867887984	-0.207496093497556	0.214865882505835	-0.96570051549213	0.334194061485261	0.525494267458798	1026	hypothetical protein	NA	K11435	NA	              Membrane transport	               03070 Bacterial secretion system	NA	
LFTS_00656	533.182006192968	-0.151315239821203	0.156768835799281	-0.96521249934483	0.334438387633746	0.525546037710173	972	UDP-galactose 4-epimerase	Extracellular polysaccharide production and export	K01784	 Carbohydrate metabolism	              Carbohydrate metabolism	               00052 Galactose metabolism	COG1087	M
LFTS_00625	75.0372080445176	-0.260151777917503	0.269984346935576	-0.963580966342398	0.335256053236591	0.52642500390153	774	putative membrane protein	NA	K08977	NA	              Amino acid metabolism	               00340 Histidine metabolism	NA	
LFTS_01280	198.268305218417	-0.196050361932153	0.203529740268825	-0.963251668641681	0.335421241423984	0.52642500390153	489	inner membrane protein	NA	K07038	NA	              Amino acid metabolism	               00270 Cysteine and methionine metabolism	COG1988	R
LFTS_01564	378.739591472455	0.174304002978789	0.181106110425917	0.962441314480603	0.33582796889233	0.526730807991377	339	putative membrane protein	Extracellular polysaccharide production and export	K08972	NA	              Translation	               03010 Ribosome	COG1950	S
LFTS_00723	1279.77322616764	-0.134934905587655	0.140412822948306	-0.960987057694382	0.336558675339568	0.527383733457246	1716	type II secretion system protein E (GspE)	NA	K02454	 Cellular community - prokaryotes; Membrane transport	              Membrane transport	               03070 Bacterial secretion system	COG2804	NUW
LFTS_01233	458.261889930402	-0.172532177196623	0.179613539151486	-0.960574453416395	0.336766178752134	0.527383733457246	264	BrnA antitoxin of type II toxin-antitoxin system	NA	NA	NA	NA	NA	NA	NA
LFTS_01750	47.8870071336664	-0.314910910946526	0.327913723655427	-0.960346848055179	0.336880679296101	0.527383733457246	2061	Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter%2C MnhD subunit	NA	K12137	NA	              Amino acid metabolism	               00260 Glycine, serine and threonine metabolism	COG0651	CP
LFTS_02438	13999.7972181379	-0.18134161607538	0.189335082603475	-0.957781376709589	0.338173011972563	0.529073699033223	276	DNA-binding protein HU-beta	NA	K03530	NA	              Energy metabolism	               00190 Oxidative phosphorylation	COG0776	L
LFTS_01076	43.8735187389706	0.302733335631423	0.316930840356882	0.955203145552288	0.339474975416886	0.530776596783887	1134	Competence protein ComGC	NA	NA	NA	NA	NA	NA	NA
LFTS_01719	1012.68419930288	0.132768269585601	0.139193872427078	0.953837027956508	0.34016614310339	0.531522961505359	1389	oxygen-dependent protoporphyrinogen oxidase	NA	K00231	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00860 Porphyrin and chlorophyll metabolism	COG1232	H
LFTS_01812	267.938530393333	-0.218302969284109	0.229148859880964	-0.952668799650632	0.340757906386301	0.531814742063356	708	lipopolysaccharide transport system ATP-binding protein	Lipopolysaccharide synthesis	K09691	 Membrane transport	              Membrane transport	               02010 ABC transporters	COG1134	GM
LFTS_01011	190.558677209535	0.200784318264367	0.21076979508442	0.952623776969307	0.340780725706728	0.531814742063356	1299	DNA repair protein radc	NA	K03630	NA	              Signal transduction	               02020 Two-component system	COG2003	L
LFTS_02400	1182.472541715	0.134048083731624	0.140815652008691	0.951940226952551	0.341127296799248	0.532021618471098	843	protein NrfD	NA	NA	NA	NA	NA	NA	NA
LFTS_01760	135.344068505636	-0.211482105849584	0.222839385654463	-0.949033786053917	0.342603428739127	0.533988792379606	279	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00527	28.4742251884864	-0.33410033847429	0.352332752871128	-0.948252286373423	0.343001034745308	0.534090176606378	159	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01570	246.50907995221	-0.177031157064059	0.186729616167708	-0.948061484285715	0.34309815448125	0.534090176606378	540	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_02286	587.431159719669	0.155907294487699	0.164816357813121	0.945945515095509	0.344176376890094	0.535299745407903	753	phosphate ABC transporter ATP-binding protein%2C PhoT family	NA	K02036	 Membrane transport	              Membrane transport	               02010 ABC transporters	COG1117	P
LFTS_00508	88.4319992193565	-0.250781540190221	0.265190369005396	-0.945666093119386	0.344318921846841	0.535299745407903	306	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01472	45.486083994945	0.302862850632662	0.320458050079847	0.945093595112367	0.344611094929445	0.535299745407903	456	hypothetical protein	NA	K03048	 Nucleotide metabolism; Transcription	              Nucleotide metabolism	               00230 Purine metabolism	COG3343	K
LFTS_01808	421.607817479676	0.160759678063084	0.170143428053245	0.944848002079607	0.344736481254245	0.535299745407903	1038	heptosyltransferase-2	Lipopolysaccharide synthesis	K02843	 Glycan biosynthesis and metabolism	              Glycan biosynthesis and metabolism	               00540 Lipopolysaccharide biosynthesis	COG0859	M
LFTS_01181	23.2184419164709	-0.360226622569769	0.381644631426342	-0.943879706164012	0.345231123535471	0.535689668112157	891	SIR2-like domain-containing protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00738	48.446004932756	0.289523586549084	0.306866787342403	0.943482965545024	0.345433924317791	0.535689668112157	2268	cellulose synthase subunit	Cellulose production	NA	NA	NA	NA	NA	NA
LFTS_00515	226.663810831348	-0.197255006506354	0.209157840363429	-0.943091620011031	0.345634041694248	0.535689668112157	777	Hpt domain-containing protein	Quorum sensing	K10715	 Cellular community - prokaryotes; Signal transduction	              Signal transduction	               02020 Two-component system	COG0642;COG0784	T
LFTS_00397	55.5147740133257	-0.280507796389631	0.298331053902002	-0.940256780917533	0.347085862704966	0.537604644663268	1002	hypothetical protein	NA	K01163	NA	              Carbohydrate metabolism	               00520 Amino sugar and nucleotide sugar metabolism	COG4866	S
LFTS_00469	453.667646963696	0.14295551793945	0.152218097656555	0.939149287373148	0.347654101882952	0.538149500174981	897	NADH dehydrogenase	NA	K00329	 Energy metabolism	              Energy metabolism	               00190 Oxidative phosphorylation	NA	
LFTS_01104	64.3808913270189	0.256146391146433	0.273049479420643	0.938095145575538	0.348195516330363	0.538652180209884	1140	hypothetical protein	NA	K06871	NA	              Metabolism of cofactors and vitamins	               00130 Ubiquinone and other terpenoid-quinone biosynthesis	COG0641	O
LFTS_02009	1473.70856188795	0.223591621537074	0.238649909751794	0.936902183493883	0.348808875941178	0.539142487316996	723	hypothetical protein	NA	K09857	NA	              Membrane transport	               02060 Phosphotransferase system (PTS)	COG3009	S
LFTS_01047	103.889887115079	0.238653399886762	0.254798647682993	0.936635268895469	0.348946203577251	0.539142487316996	966	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01119	65.6501038129935	0.26195433133168	0.280319201365255	0.934485864884991	0.350053324005189	0.540220180951421	1086	twitching motility protein PilT	NA	K02669	NA	              Replication and repair	               03030 DNA replication	COG2805	NW
LFTS_02017	668.013319012032	-0.144819933900091	0.154980886836426	-0.934437380352201	0.3500783232151	0.540220180951421	615	outer membrane lipoprotein	NA	K07285	NA	              Metabolism of cofactors and vitamins	               00790 Folate biosynthesis	COG3065	M
LFTS_01072	15.6070938063795	-0.39659242970061	0.425199524070339	-0.932720775188364	0.350964155432523	0.541203902768112	723	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_02174	318.227067619761	0.156106319774645	0.167431619923221	0.932358653916327	0.351151204812938	0.541203902768112	858	undecaprenyl-diphosphatase	NA	K06153	 Glycan biosynthesis and metabolism	              Glycan biosynthesis and metabolism	               00550 Peptidoglycan biosynthesis	COG1968	I
LFTS_01588	1057.43048242964	-0.128381418167994	0.138350013243279	-0.927946554961616	0.353435293530055	0.544386703665252	1248	phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase	NA	K13038	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00770 Pantothenate and CoA biosynthesis	COG0452	H
LFTS_02078	1999.43872880004	-0.149076110440728	0.16127674049888	-0.924349723212339	0.355304262211042	0.546678707345209	1884	NADH-quinone oxidoreductase subunit F	NADH dehydrogenase	K00335	 Energy metabolism	              Energy metabolism	               00190 Oxidative phosphorylation	COG1894	C
LFTS_00305	162.107422078624	-0.200318150612782	0.216739039820187	-0.924236587829181	0.355363150068326	0.546678707345209	912	oligopeptide transport system permease protein	NA	K15581	 Cellular community - prokaryotes; Drug resistance; Membrane transport	              Membrane transport	               02010 ABC transporters	COG0601	EP
LFTS_00118	345.478697585523	-0.153833611614487	0.166693224820347	-0.922854613798971	0.356082975416034	0.547447295537576	690	Tetratricopeptide repeat-containing protein	NA	K09667	 Endocrine and metabolic diseases; Glycan biosynthesis and metabolism	              Glycan biosynthesis and metabolism	               00514 Other types of O-glycan biosynthesis	NA	
LFTS_00004	1172.63572955924	0.16408928436612	0.178012817073819	0.921783538193628	0.356641495770332	0.54796709424292	2451	DNA gyrase subunit A	NA	K02469	NA	              Nucleotide metabolism	               00230 Purine metabolism	COG0188	L
LFTS_01390	626.370743471115	-0.170657785979251	0.185523560950409	-0.919871228780846	0.357640055525879	0.549161938256538	918	fructose-bisphosphate aldolase	NA	K16305	 Carbohydrate metabolism; Overview; Energy metabolism; Amino acid metabolism	              Overview	               01200 Carbon metabolism	COG1830	G
LFTS_00414	1358.4953407979	-0.146785253316219	0.159768222166764	-0.918738728675382	0.358232247443551	0.549731708113992	483	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00635	108.101815457908	-0.263313705192237	0.287209305879388	-0.916800743576234	0.359247062923753	0.550948919450001	147	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01709	160.910822790824	-0.203233818941414	0.222560415128093	-0.913162472421003	0.361157097792037	0.553536710919238	558	TolB amino-terminal domain-containing protein	NA	K07337	NA	              Overview	               01200 Carbon metabolism	COG3417	M
LFTS_00848	202.581113837678	0.176800587629776	0.193850815092147	0.912044592362087	0.361745243900679	0.554096535019771	1197	Septal ring factor EnvC%2C activator of murein hydrolases AmiA and AmiB	NA	K06194	NA	              Glycan biosynthesis and metabolism	               00550 Peptidoglycan biosynthesis	COG0739	M
LFTS_00725	2389.38734434041	-0.122559271521295	0.134550179718891	-0.910881514817387	0.362357806423647	0.554693046040139	972	general secretion pathway protein C	NA	K02452	 Cellular community - prokaryotes; Membrane transport	              Membrane transport	               03070 Bacterial secretion system	COG3031	U
LFTS_00710	1227.82902628614	0.147871592456857	0.162434985799019	0.910343247358164	0.362641517607864	0.554785730937324	1041	chemotaxis protein CheZ	Chemotaxis	K03414	 Cell motility	              Cell motility	               02030 Bacterial chemotaxis	COG3143	NT
LFTS_01166	4.47704910755865	-0.3877116518893	0.426153172089976	-0.909794123995023	0.362931094035327	0.554887269232363	1434	nitrogenase molybdenum-iron protein NifN	Nitrogenase genes	K02592	NA	              Xenobiotics biodegradation and metabolism	               00930 Caprolactam degradation	COG2710	P
LFTS_02245	342.497216324281	-0.163648500519466	0.180008802332247	-0.909113878872521	0.363290017279516	0.555094642259912	597	XTP/dITP diphosphohydrolase	NA	K02428	 Nucleotide metabolism	              Nucleotide metabolism	               00230 Purine metabolism	COG0127	F
LFTS_01585	799.668997622396	0.126769365040336	0.139625081098068	0.907926885652425	0.363916851859099	0.555710868379436	285	hypothetical protein	NA	K09777	NA	              Nucleotide metabolism	               00230 Purine metabolism	COG2052	M
LFTS_01077	40.6681987800285	0.311120615892647	0.343978142271555	0.904477865477369	0.365742066094616	0.557991011919503	1164	hypothetical protein	NA	K06871	NA	              Energy metabolism	               00190 Oxidative phosphorylation	COG0641	O
LFTS_00462	821.788879562357	-0.18217623043876	0.201465023154835	-0.904257362325121	0.365858949890905	0.557991011919503	924	3-hydroxyisobutyrate dehydrogenase	NA	K00020	 Amino acid metabolism	              Amino acid metabolism	               00280 Valine, leucine and isoleucine degradation	COG2084	I
LFTS_02313	90.8695668146911	-0.226732356103551	0.251320032858649	-0.902165870044562	0.366968762103317	0.559340492083903	345	nitrogen regulatory protein P-II family protein	Nitrate/nitrite regulation	K04751	 Signal transduction	              Signal transduction	               02020 Two-component system	COG0347	TE
LFTS_00961	1162.52914000044	0.120236925358331	0.13337854931523	0.901471233385215	0.36733782209505	0.559433858932635	1017	putative oxidoreductase	NA	K05275	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00750 Vitamin B6 metabolism	COG0667	R
LFTS_01881	976.784253787819	0.12266240806659	0.136109542938172	0.901203585132236	0.367480085131534	0.559433858932635	1830	GTP-binding protein LepA	NA	K03596	 Infectious diseases	              Infectious diseases	               05134 Legionellosis	COG0481	J
LFTS_00719	436.274430235929	-0.146991909236045	0.163237129919051	-0.900480848376457	0.367864412745214	0.559676211802082	1359	hypothetical protein	NA	K02461	 Cellular community - prokaryotes; Membrane transport	              Membrane transport	               03070 Bacterial secretion system	COG3297	U
LFTS_00459	247.221296196291	-0.164918827358834	0.183779366210187	-0.897374012979333	0.369519374597003	0.561170650844027	2226	two-component system%2C OmpR family%2C sensor histidine kinase KdpD	Role of potassium in the internal positive membrane potential	K07646	 Signal transduction	              Signal transduction	               02020 Two-component system	COG2205	T
LFTS_01203	11.0744759030031	-0.384430541651005	0.428505449668812	-0.897142712999632	0.369642769257842	0.561170650844027	327	nitrogen regulatory protein P-II family protein	Nitrate/nitrite regulation	K02589	NA	              Energy metabolism	               00910 Nitrogen metabolism	COG0347	TE
LFTS_00458	66.3268687279706	-0.277432092992287	0.309240843997749	-0.897139231046419	0.369644627017152	0.561170650844027	645	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01363	300.24001473046	-0.154088435684621	0.171792994833565	-0.896942484959318	0.369749608239146	0.561170650844027	570	hypothetical protein	NA	K00573	NA	              Carbohydrate metabolism	               00500 Starch and sucrose metabolism	COG2518	O
LFTS_00962	702.381446027977	0.131127842213066	0.146412747902878	0.895603996859946	0.370464300283981	0.561912294390469	804	alpha-ribazole phosphatase	NA	K15634	 Energy metabolism; Overview; Amino acid metabolism; Carbohydrate metabolism	              Overview	               01200 Carbon metabolism	COG0406	G
LFTS_02436	444.758648233084	0.16633426423151	0.18623485773267	0.893142488235333	0.371780872130514	0.563221999381698	3012	Multidrug efflux pump subunit AcrB	NA	K03296	NA	              Energy metabolism	               00910 Nitrogen metabolism	COG0841	V
LFTS_02284	671.958799195519	0.140693945272182	0.157526882196239	0.893142448518166	0.371780893397171	0.563221999381698	819	thymidylate synthase (FAD)	NA	K03465	 Nucleotide metabolism; Metabolism of cofactors and vitamins	              Nucleotide metabolism	               00240 Pyrimidine metabolism	COG1351	F
LFTS_02458	8202.98685568579	0.165903377188166	0.185882728429785	0.89251636550425	0.372116224845747	0.563386683901661	1239	pyruvate ferredoxin oxidoreductase alpha subunit	Reductive TCA cycle carbon dioxide fixation	K00169	 Carbohydrate metabolism; Overview; Energy metabolism; Xenobiotics biodegradation and metabolism	              Overview	               01200 Carbon metabolism	COG0674	C
LFTS_02112	96.5494215243054	-0.384333212276585	0.431096908309696	-0.891523935496387	0.372648156575488	0.56384864105092	246	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_02227	515.655783175769	-0.150990184466821	0.169830120056001	-0.889065993812125	0.373967613616087	0.565500904774691	720	protein gp37	NA	NA	NA	NA	NA	NA	NA
LFTS_01658	2144.88161100548	0.171053600962655	0.193125002699587	0.885714426260673	0.37577143249637	0.567883149657129	624	large subunit ribosomal protein L3	NA	K02906	 Translation	              Translation	               03010 Ribosome	COG0087	J
LFTS_01052	630.292728572101	-0.16855010303728	0.190542427202609	-0.884580434456496	0.376382963042045	0.568461753415871	459	hypothetical protein	NA	K11581	NA	              Replication and repair	               03030 DNA replication	NA	
LFTS_01837	209.481841397687	-0.211860215540148	0.239738469267163	-0.883713891173855	0.376850679660685	0.568822580228575	528	DinB family protein	NA	NA	NA	NA	NA	NA	NA
LFTS_02485	920.341427902921	0.15451080178772	0.175259647882079	0.881610819460734	0.377987302207127	0.569720972220823	543	hypothetical protein	NA	K14166	NA	              Overview	               01200 Carbon metabolism	COG1276;COG2372	P
LFTS_01202	32.4790239659968	-0.339013788743929	0.384890145576575	-0.880806621422009	0.378422495286183	0.569720972220823	1299	MFS transporter%2C NNP family%2C nitrate/nitrite transporter	Nitrite uptake & assimilation to ammonia	K02575	 Energy metabolism	              Energy metabolism	               00910 Nitrogen metabolism	COG2223	P
LFTS_02094	35316.7641983515	0.151255835776923	0.171804631734882	0.880394400602261	0.378645688804838	0.569720972220823	558	Cytochrome C oxidase%2C cbb3-type%2C subunit III	Cytochrome cbb3 oxidase	K00406	 Energy metabolism; Signal transduction	              Energy metabolism	               00190 Oxidative phosphorylation	COG2010	C
LFTS_01955	596.717762686146	-0.137809049886313	0.156549498309415	-0.88029058779823	0.378701910151	0.569720972220823	597	anthranilate synthase%2C component II	NA	K01664	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00790 Folate biosynthesis	COG0512	EH
LFTS_00525	78.5057314270651	-0.235810963762564	0.267965023455573	-0.880006505034267	0.378855785604674	0.569720972220823	900	hypothetical protein	NA	K13018	 Carbohydrate metabolism	              Carbohydrate metabolism	               00520 Amino sugar and nucleotide sugar metabolism	COG0110	R
LFTS_01767	44.0641859722205	-0.275672217003652	0.31335331155794	-0.879748854840742	0.378995376938082	0.569720972220823	1221	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00608	854.00157678706	-0.128677398721753	0.146304296663694	-0.87951893181606	0.379119972792082	0.569720972220823	651	hypothetical protein	NA	K05810	NA	              Cell growth and death	               04112 Cell cycle - Caulobacter	COG1496	P
LFTS_00416	660.289460186534	-0.134424296977421	0.152889515693326	-0.879225082032806	0.3792792473956	0.569720972220823	312	ferredoxin%2C 2Fe-2S	NA	K04755	NA	              Amino acid metabolism	               00310 Lysine degradation	COG0633	C
LFTS_02244	431.18890717747	0.140523796381342	0.160761209880019	0.874115070956601	0.382055590844545	0.573544806062523	1029	beta-N-acetylhexosaminidase	NA	K01207	 Glycan biosynthesis and metabolism; Carbohydrate metabolism; Drug resistance	              Carbohydrate metabolism	               00520 Amino sugar and nucleotide sugar metabolism	COG1472	G
LFTS_02119	1259.2592556437	-0.129108760472479	0.14843723563514	-0.86978688278613	0.384416881187916	0.576715069910763	1170	2%2C3-diketo-5-methylthiopentyl-1-phosphate enolase	NA	K08965	 Amino acid metabolism	              Amino acid metabolism	               00270 Cysteine and methionine metabolism	COG1850	G
LFTS_01633	2432.35953005333	0.131580858223196	0.151347693822004	0.869394537177056	0.384631370037025	0.576715069910763	1503	trehalose 6-phosphate synthase	Lipopolysaccharide synthesis	K00697	 Carbohydrate metabolism	              Carbohydrate metabolism	               00500 Starch and sucrose metabolism	COG0380	G
LFTS_00967	6.93299770976388	-0.3768640405675	0.434088390253455	-0.868173508043966	0.385299354642117	0.577368412079748	195	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01301	382.344416997932	-0.143761589930138	0.165895619387215	-0.866578577910404	0.386172955189864	0.578328895543375	1074	lipid-A-disaccharide kinase	Lipopolysaccharide synthesis	K00912	 Glycan biosynthesis and metabolism	              Glycan biosynthesis and metabolism	               00540 Lipopolysaccharide biosynthesis	COG1663	M
LFTS_01411	238.403466012679	0.18749187703625	0.216554271246774	0.865796254937836	0.386601903312123	0.578609307322446	1716	Sel1 repeat-containing protein	NA	K13582	 Cell growth and death	              Cell growth and death	               04112 Cell cycle - Caulobacter	COG0790;COG3409	TM
LFTS_01874	138.128736605864	-0.230599821397852	0.266675180061355	-0.864721723801954	0.387191543068893	0.578609307322446	549	3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (KDO 8-P phosphatase)	NA	K03270	 Glycan biosynthesis and metabolism	              Glycan biosynthesis and metabolism	               00540 Lipopolysaccharide biosynthesis	COG1778	MR
LFTS_00987	303.896609932429	-0.180970804189879	0.209399198888457	-0.86423828338655	0.387457005645914	0.578609307322446	1086	hypothetical protein	NA	K14440	NA	              Replication and repair	               03430 Mismatch repair	NA	
LFTS_01795	455.403464580266	0.144205510887718	0.166897760140305	0.864035028190247	0.387568648489698	0.578609307322446	753	Transposase (or an inactivated derivative)	NA	K07493	NA	              Signal transduction	               02020 Two-component system	COG3328	X
LFTS_01806	802.290121117445	0.123288363185012	0.142824355235664	0.863216662043267	0.388018354333682	0.578609307322446	675	Transposase (or an inactivated derivative)	NA	K07493	NA	              Overview	               01200 Carbon metabolism	COG3328	X
LFTS_01248	89.2208404538926	-0.213063886376978	0.246836679666961	-0.863177574193793	0.388039841711371	0.578609307322446	1425	Tetratricopeptide repeat protein	putative pel operon	K12284	NA	              Translation	               00970 Aminoacyl-tRNA biosynthesis	NA	
LFTS_00320	421.173162467065	0.144220999336891	0.167096975612547	0.863097604299559	0.38808380503094	0.578609307322446	720	hypothetical protein	NA	K06966	NA	              Signal transduction	               02020 Two-component system	COG1611	R
LFTS_02041	3515.17252146764	0.139160353600414	0.161280648505979	0.862845945186383	0.388222174020048	0.578609307322446	384	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00817	828.964078464952	-0.127427453628486	0.148103017022652	-0.860397419243636	0.389570007951758	0.579765005791468	2532	DNA mismatch repair protein MutS	NA	K03555	 Replication and repair	              Replication and repair	               03430 Mismatch repair	COG0249	L
LFTS_00054	1644.62025143642	-0.137566574755399	0.160033642051019	-0.859610348126318	0.390003868823235	0.579765005791468	759	triosephosphate isomerase	NA	K01803	 Carbohydrate metabolism; Overview; Energy metabolism	              Overview	               01200 Carbon metabolism	COG0149	G
LFTS_01245	205.954935322898	0.17296914302473	0.201341693452821	0.859082587706858	0.390294953118032	0.579765005791468	1317	hypothetical protein	putative pel operon	K02488	 Cell growth and death; Signal transduction	              Signal transduction	               02020 Two-component system	COG3706	TK
LFTS_01470	21.9473706417213	0.335153634697282	0.390378512273725	0.858535047805807	0.390597086230195	0.579765005791468	951	conjugation TrbI-like protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01128	36.0225600878187	-0.283530607917543	0.330579850948495	-0.857676616115716	0.391071055713353	0.579765005791468	477	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01285	100.038823088847	-0.201625433629571	0.235181409934609	-0.857318755277604	0.391268746019519	0.579765005791468	546	RNA polymerase%2C sigma subunit%2C SigZ	NA	K03088	NA	              Amino acid metabolism	               00270 Cysteine and methionine metabolism	COG1595	K
LFTS_02506	463.593597692223	-0.148168138191718	0.172851203770029	-0.857200499389347	0.391334086544059	0.579765005791468	450	Transposase DDE domain group 1	NA	NA	NA	NA	NA	NA	NA
LFTS_02125	466.826070266735	-0.160263317932348	0.186984609425987	-0.857093631525779	0.39139314048342	0.579765005791468	663	thymidylate kinase	NA	K00943	 Nucleotide metabolism	              Nucleotide metabolism	               00240 Pyrimidine metabolism	COG0125	F
LFTS_01993	2017.14952229153	-0.120287043461062	0.140502639765193	-0.856119455563862	0.391931708177872	0.579765005791468	1542	uroporphyrinogen III methyltransferase / synthase	NA	K13542	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00860 Porphyrin and chlorophyll metabolism	COG0007;COG1587	H
LFTS_02161	634.993061368341	-0.134382367574592	0.157006851756287	-0.85590129393325	0.392052379195341	0.579765005791468	945	[acyl-carrier-protein] S-malonyltransferase	NA	K00645	 Overview; Lipid metabolism	              Overview	               01212 Fatty acid metabolism	COG0331	I
LFTS_01914	1475.15490002766	-0.103563159940141	0.121022496687219	-0.855734782994922	0.392144496000449	0.579765005791468	177	hypothetical protein	NA	K02571	NA	              Nucleotide metabolism	               00240 Pyrimidine metabolism	NA	
LFTS_00425	1772.5435593451	-0.114538537414201	0.133881169396227	-0.855523879353179	0.392261190479076	0.579765005791468	1443	putative hemolysin	NA	K03699	NA	              Energy metabolism	               00920 Sulfur metabolism	COG1253	R
LFTS_02304	801.857393018898	0.163488618356537	0.191112978193496	0.855455343231634	0.392299116533886	0.579765005791468	2271	penicillin-binding protein 1B	NA	K05365	 Glycan biosynthesis and metabolism	              Glycan biosynthesis and metabolism	               00550 Peptidoglycan biosynthesis	COG0744	M
LFTS_00605	240.070407138851	-0.172098984511486	0.201306133631116	-0.854911777436697	0.392599990042779	0.579765005791468	861	hypothetical protein	NA	K03589	 Cell growth and death	              Cell growth and death	               04112 Cell cycle - Caulobacter	COG1589	D
LFTS_00342	111.411818887836	-0.206531143625703	0.241632473802131	-0.854732562953553	0.392699219160245	0.579765005791468	1221	putative permease	NA	K08184	NA	              Amino acid metabolism	               00260 Glycine, serine and threonine metabolism	NA	
LFTS_01315	361.628766395484	0.15569992028205	0.1821736075983	0.854678799716007	0.392728990246514	0.579765005791468	1083	heptosyltransferase-3	Lipopolysaccharide synthesis	K02849	 Glycan biosynthesis and metabolism	              Glycan biosynthesis and metabolism	               00540 Lipopolysaccharide biosynthesis	COG0859	M
LFTS_01330	389.298120226281	0.136412085880642	0.159978215068596	0.852691635683962	0.393830330543662	0.581045817051361	813	dolichol-phosphate mannosyltransferase	Lipopolysaccharide synthesis	K00721	 Glycan biosynthesis and metabolism	              Glycan biosynthesis and metabolism	               00510 N-Glycan biosynthesis	COG0463	M
LFTS_00915	296.452132341632	-0.145270317401738	0.17099539991891	-0.849556873872795	0.395571497372697	0.583268530527002	2931	Ti-type conjugative transfer relaxase TraA	NA	K03581	 Replication and repair	              Replication and repair	               03440 Homologous recombination	COG0507	L
LFTS_01461	430.082669291966	-0.150570304559764	0.17815830284198	-0.845148961108563	0.398027674718788	0.586542263989867	726	putative ABC transport system ATP-binding protein	NA	K02003	NA	              Carbohydrate metabolism	               00052 Galactose metabolism	COG1136;COG4181	MQ
LFTS_00388	31.7282890584048	-0.311075813795678	0.368330934504403	-0.844555221011336	0.398359219468505	0.586683068482645	108	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01474	265.430016802986	-0.167204881139555	0.198171882349318	-0.843736655055951	0.398816579744929	0.587008891205384	945	integrase/recombinase XerD	NA	K04763	NA	              Folding, sorting and degradation	               03018 RNA degradation	COG0582	LX
LFTS_01185	19.7602895726742	-0.34420072981048	0.408395116345614	-0.842813040690702	0.399333013505418	0.587421225783709	423	nitrogen regulatory protein P-II family protein	Nitrate/nitrite regulation	K02590	NA	              Signal transduction	               02020 Two-component system	COG0347	TE
LFTS_00032	401.609742161605	0.170734887630409	0.202875350070927	0.841575319873597	0.400025708671572	0.588065540865848	1191	hypothetical protein	NA	K02016	 Membrane transport	              Membrane transport	               02010 ABC transporters	COG0614	P
LFTS_00766	1004.74981014517	-0.120966789981854	0.143805161140664	-0.841185316454179	0.400244125158896	0.588065540865848	363	Cytochrome c%2C mono- and diheme variants	Cytochrome c	K00406	 Energy metabolism; Signal transduction	              Energy metabolism	               00190 Oxidative phosphorylation	COG2010	C
LFTS_01888	302.137384478548	0.15362183727813	0.183477260191337	0.837279982914113	0.402435208137848	0.59093557438316	726	DNA-(apurinic or apyrimidinic site) lyase /endonuclease III	NA	K10773	 Replication and repair	              Replication and repair	               03410 Base excision repair	COG0177	L
LFTS_01785	317.953115848346	-0.183583779616185	0.219579431129814	-0.836070021092514	0.403115512429134	0.591585102655743	285	Transposase	NA	K07483	NA	              Carbohydrate metabolism	               00500 Starch and sucrose metabolism	COG2963	X
LFTS_02127	1675.89951392155	-0.110689515590082	0.132588978488341	-0.834831950981621	0.403812333411156	0.592258089003029	813	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01302	308.278317531011	-0.148431932272224	0.178086782530972	-0.833480902752623	0.404573563899821	0.592908730059396	969	KDO2-lipid IV(A) lauroyltransferase	Lipopolysaccharide synthesis	K02517	 Glycan biosynthesis and metabolism	              Glycan biosynthesis and metabolism	               00540 Lipopolysaccharide biosynthesis	COG1560	I
LFTS_00140	215.7684780601	0.170251146124295	0.204334507139794	0.833198212614275	0.404732950487046	0.592908730059396	219	hypothetical protein	NA	K09937	NA	              Overview	               01230 Biosynthesis of amino acids	COG3242	S
LFTS_00154	263.781575927596	0.158745918804608	0.191071083574301	0.830821262092631	0.4060746094041	0.594523839210008	645	DNA replication and repair protein RecR	NA	K06187	 Replication and repair	              Replication and repair	               03440 Homologous recombination	COG0353	L
LFTS_01509	511.750952363984	0.140552704345257	0.169449829271821	0.829465010081487	0.406841328203759	0.595295786883193	1392	replicative DNA helicase	NA	K02314	 Replication and repair; Cell growth and death	              Replication and repair	               03030 DNA replication	COG0305	L
LFTS_01954	730.159249623266	-0.123631248137544	0.14920519392147	-0.828598823460623	0.407331453988124	0.595335580002848	1026	anthranilate phosphoribosyltransferase	NA	K00766	 Overview; Amino acid metabolism	              Overview	               01230 Biosynthesis of amino acids	COG0547	E
LFTS_01403	1333.96217050538	-0.135699610005743	0.163821446960822	-0.828338490003665	0.407478830677944	0.595335580002848	798	Outer membrane protein OmpA	NA	K03286	NA	              Transport and catabolism	               04144 Endocytosis	COG2885	M
LFTS_01165	12.4111969298174	-0.349086967647823	0.421626995865431	-0.827952126099724	0.407697612721963	0.595335580002848	1401	nitrogenase molybdenum-cofactor synthesis protein NifE	Nitrogenase genes	K02587	NA	              Energy metabolism	               00910 Nitrogen metabolism	COG2710	P
LFTS_00670	857.196273804873	-0.122107162451924	0.14752146675511	-0.827724704328125	0.407826425078379	0.595335580002848	771	16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase	NA	K02528	NA	              Energy metabolism	               00190 Oxidative phosphorylation	COG0030	J
LFTS_02350	778.617311318381	-0.124099053981933	0.150063525908317	-0.826976796865036	0.408250213051015	0.595368193878829	804	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1%2C7-dioic acid hydratase (catechol pathway)	NA	K16164	 Amino acid metabolism	              Amino acid metabolism	               00350 Tyrosine metabolism	COG0179	Q
LFTS_02418	1390.88546417566	0.125306780360896	0.151549002652886	0.826840019844297	0.408327743589462	0.595368193878829	1473	Outer membrane protein TolC	NA	K12340	 Drug resistance; Signal transduction; Membrane transport; Infectious diseases; Environmental adaptation	              Membrane transport	               03070 Bacterial secretion system	COG1538	M
LFTS_01732	310.145948249531	-0.179001566399103	0.216600778785182	-0.826412385971298	0.40857019967365	0.595372518399	162	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01172	5.57837437755716	-0.353425564319182	0.428025203776454	-0.825712040321266	0.408967460576081	0.595557752287965	507	Tetratricopeptide repeat-containing protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01349	869.95462001984	-0.111928008929817	0.135692915962748	-0.824862581334347	0.409449612242861	0.595557752287965	576	Methyltransferase domain-containing protein	NA	K03183	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00130 Ubiquinone and other terpenoid-quinone biosynthesis	COG2226	H
LFTS_01191	100.489376365214	-0.226203893736165	0.274349968582611	-0.824508546163916	0.409650661867403	0.595557752287965	696	molybdate transport system permease protein	NA	K02018	 Membrane transport	              Membrane transport	               02010 ABC transporters	COG0555	P
LFTS_00134	59.9036396627093	-0.245783772708211	0.29817788454464	-0.824285721536853	0.409777229696882	0.595557752287965	642	hypothetical protein	NA	K07286	NA	              Signal transduction	               02020 Two-component system	COG3056	S
LFTS_02440	4111.03604921218	-0.104549742734367	0.126868718894254	-0.824078178179675	0.409895138441154	0.595557752287965	2601	ATP-dependent Clp protease ATP-binding subunit ClpB	NA	K03695	 Aging	              Aging	               04213 Longevity regulating pathway - multiple species	COG0542	O
LFTS_00631	221.571736707468	0.146632545202042	0.178028869965523	0.82364475621532	0.410141437517073	0.595567531347806	264	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01748	131.701955628112	0.200203756926549	0.244673076465046	0.818250049490633	0.413214421802921	0.599679540339791	882	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01441	1026.78563789684	0.140191517827586	0.171468185614607	0.817594921909776	0.413588528125406	0.599781812714931	891	acetyl-CoA carboxylase carboxyl transferase subunit alpha	NA	K01962	 Carbohydrate metabolism; Overview; Energy metabolism; Lipid metabolism	              Overview	               01200 Carbon metabolism	COG0825	I
LFTS_01127	160.81637251906	0.166806718557307	0.204170176657301	0.81699845338965	0.413929311895361	0.599781812714931	2568	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00847	267.350682911517	0.151832354304362	0.185873263794899	0.81685956981904	0.414008684882872	0.599781812714931	906	Cell division protein FtsX	NA	K09811	 Membrane transport	              Membrane transport	               02010 ABC transporters	COG2177	D
LFTS_01243	21.4294474451622	-0.30450999144367	0.373556664999888	-0.815164123610967	0.414978370754259	0.600836476234763	1509	Glycosyltransferase involved in cell wall bisynthesis	putative pel operon	K08256	NA	              Glycan biosynthesis and metabolism	               00563 Glycosylphosphatidylinositol(GPI)-anchor biosynthesis	COG0438	M
LFTS_00606	1457.53428666505	-0.113963662266245	0.139923166496669	-0.814473150655567	0.415373947422405	0.601059157911583	1278	cell division protein FtsA	NA	K03590	 Cell growth and death	              Cell growth and death	               04112 Cell cycle - Caulobacter	COG0849	D
LFTS_01845	1412.04516877999	-0.203330868166452	0.250705578567991	-0.811034478482132	0.417345870995415	0.603561277076557	1281	diguanylate cyclase (GGDEF) domain-containing protein	Putative diguanylate cyclases (GGDEF domain-containing proteins)	K13069	NA	              Nucleotide metabolism	               00230 Purine metabolism	COG2199	T
LFTS_01253	849.030614580466	-0.144167157293436	0.177952718668009	-0.810143044582512	0.417857967378363	0.603950527268959	1686	dihydroxy-acid dehydratase	NA	K01687	 Metabolism of cofactors and vitamins; Amino acid metabolism; Overview	              Overview	               01210 2-Oxocarboxylic acid metabolism	COG0129	EG
LFTS_01286	176.254947584799	-0.169092926354665	0.209092534077321	-0.808699015011868	0.418688294888248	0.604799012836829	1056	Methyltransferase domain-containing protein	NA	K07755	NA	              Amino acid metabolism	               00270 Cysteine and methionine metabolism	NA	
LFTS_01070	5.76746350939683	0.348871047598483	0.432300446158001	0.807010611945968	0.419660369279782	0.60577094333005	339	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_02142	215.847556225835	0.145086648184513	0.179855586032281	0.80668413689677	0.419848485662782	0.60577094333005	1410	GTP-binding protein	NA	K03977	NA	              Signal transduction	               02020 Two-component system	COG1160	R
LFTS_00791	1042.45121850116	0.109956574144215	0.136554076073306	0.805223668938212	0.4206906203414	0.606290818106201	1584	phosphodiesterase	NA	K07037	NA	              Cell growth and death	               04112 Cell cycle - Caulobacter	COG1480	R
LFTS_00269	1680.42320378565	0.106537597991023	0.132309773543946	0.80521336510063	0.420696565258727	0.606290818106201	492	LTXXQ motif family protein	NA	K06006	NA	              Metabolism of other amino acids	               00410 beta-Alanine metabolism	COG3678	O
LFTS_00602	1396.10189854318	-0.11541198803156	0.143500038896164	-0.804264506959968	0.421244231230762	0.60672836549228	1395	UDP-N-acetylmuramate--L-alanine ligase	NA	K01924	 Metabolism of other amino acids; Glycan biosynthesis and metabolism	              Metabolism of other amino acids	               00471 D-Glutamine and D-glutamate metabolism	COG0773	M
LFTS_00114	134.784921480315	0.181580460329052	0.22630651221826	0.802365157543183	0.422341761723614	0.60795693088877	576	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01003	2468.46108252149	0.152619417435572	0.190315390275238	0.801928930786156	0.422594069807872	0.607968088855538	828	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00409	526.474209482275	-0.116995544490046	0.146218179820417	-0.800143625325786	0.423627587860271	0.609102477397706	1062	glycerol-3-phosphate dehydrogenase (NAD(P)+)	NA	K00057	 Lipid metabolism	              Lipid metabolism	               00564 Glycerophospholipid metabolism	COG0240	C
LFTS_01169	19.1356014235555	-0.318288670900204	0.398437386536328	-0.798842381903795	0.424381812048178	0.609774122477886	1572	nitrogen fixation protein NifB	Nitrogenase genes	K02585	NA	              Cell motility	               02030 Bacterial chemotaxis	COG0535	R
LFTS_01303	504.111114536024	-0.162481788386898	0.203485914378249	-0.798491575612797	0.424585279971529	0.609774122477886	1710	Glycosyltransferase family 9 (heptosyltransferase)	Lipopolysaccharide synthesis	K02843	 Glycan biosynthesis and metabolism	              Glycan biosynthesis and metabolism	               00540 Lipopolysaccharide biosynthesis	COG0859	M
LFTS_00461	1094.54860071467	-0.12329213502456	0.154531834213737	-0.797842953536886	0.424961631408412	0.609836199835398	930	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_02153	538.777415462841	0.116837342759179	0.146598992822438	0.796985985440526	0.42545917063899	0.609836199835398	624	phosphoribosylglycinamide formyltransferase-1	NA	K11175	 Metabolism of cofactors and vitamins; Nucleotide metabolism	              Nucleotide metabolism	               00230 Purine metabolism	COG0299	F
LFTS_01969	1944.02678796672	-0.140980847512369	0.176931738812524	-0.796809257957676	0.425561817507687	0.609836199835398	432	Cytochrome c	NA	K02305	 Energy metabolism	              Energy metabolism	               00910 Nitrogen metabolism	NA	
LFTS_01171	11.4113121674024	0.337204331910576	0.423451875892515	0.796322678226058	0.425844507467691	0.609836199835398	393	Iron-sulfur cluster assembly accessory protein	NA	K13628	NA	              Metabolism of terpenoids and polyketides	               00523 Polyketide sugar unit biosynthesis	COG0316	O
LFTS_01967	984.058830473495	-0.12229549305183	0.153578796027443	-0.796304543434346	0.425855045420053	0.609836199835398	468	hypothetical protein	NA	K07778	 Signal transduction	              Signal transduction	               02020 Two-component system	COG4585	T
LFTS_01146	174.858926849176	-0.169876306986173	0.213619750465481	-0.79522753217345	0.426481159110704	0.61038120987289	474	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01126	23.8061959596548	0.295581956935983	0.372716439957491	0.793047811278984	0.427749967383377	0.611844890054704	390	hypothetical protein	NA	K02472	 Carbohydrate metabolism; Cellular community - prokaryotes	              Carbohydrate metabolism	               00520 Amino sugar and nucleotide sugar metabolism	COG0677	M
LFTS_00003	2253.50819217027	-0.114733254561014	0.144817261512765	-0.792262285327782	0.428207757638037	0.612147490217458	2457	DNA gyrase subunit B	NA	K02470	NA	              Signal transduction	               02020 Two-component system	COG0187	L
LFTS_00410	312.452773097973	0.131129292781623	0.165692858257334	0.791399787297826	0.428710734065722	0.612514301659417	312	hypothetical protein	NA	K00471	 Amino acid metabolism	              Amino acid metabolism	               00310 Lysine degradation	NA	
LFTS_02114	754.822743678456	-0.163412797846922	0.206680057601251	-0.790655855932631	0.429144842742873	0.61278235442779	231	Iron-binding zinc finger CDGSH type	NA	NA	NA	NA	NA	NA	NA
LFTS_00841	2700.43280001546	0.130373698254228	0.1654293386485	0.788092966576161	0.430642328950271	0.614567640511122	1335	signal recognition particle subunit FFH/SRP54 (srp54)	NA	K03106	 Cellular community - prokaryotes; Folding, sorting and degradation; Membrane transport	              Folding, sorting and degradation	               03060 Protein export	COG0541	U
LFTS_02417	1409.50470383335	0.111160548638017	0.141152517074237	0.787520838750285	0.430977034511106	0.614692431322208	933	thioredoxin reductase (NADPH)	Oxidative stress response	K00384	 Nucleotide metabolism; Metabolism of other amino acids	              Nucleotide metabolism	               00240 Pyrimidine metabolism	COG0492	O
LFTS_02459	1622.32473388312	-0.113155963614287	0.144122020803314	-0.785140001393078	0.432371488661985	0.616327706888587	588	DnaJ domain-containing protein	NA	K05801	NA	              Overview	               01200 Carbon metabolism	COG1076	O
LFTS_01423	85.3990136696057	0.212975284268084	0.271609621440936	0.784122753598393	0.432968085427461	0.61657664917394	951	Transposase	NA	K07485	NA	              Metabolism of other amino acids	               00471 D-Glutamine and D-glutamate metabolism	COG3464	X
LFTS_01051	37.4082385559037	-0.289103309776653	0.368755871021744	-0.78399649333205	0.433042167923451	0.61657664917394	414	single-strand DNA-binding protein	NA	K03111	 Replication and repair	              Replication and repair	               03030 DNA replication	COG0629	L
LFTS_00907	1653.3077256371	-0.106770410403463	0.136277595678167	-0.783477356436577	0.43334684561702	0.616657274301038	1008	PEGA domain-containing protein	NA	K07286	NA	              Carbohydrate metabolism	               00030 Pentose phosphate pathway	COG3056	S
LFTS_01724	142.361620377733	0.169467979916186	0.216727550420932	0.781940180595602	0.434249729760485	0.617441082232479	747	Site-specific recombinase XerD	NA	K14059	NA	              Folding, sorting and degradation	               04141 Protein processing in endoplasmic reticulum	COG0582	LX
LFTS_01274	45.6701590422492	0.249365190324487	0.319006119000172	0.781694066264456	0.434394389712231	0.617441082232479	159	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01779	1305.8591804377	-0.12758912210011	0.163595505793731	-0.77990603397737	0.435446186544521	0.617993776226542	1029	pyruvate dehydrogenase E1 component alpha subunit	NA	K00161	 Carbohydrate metabolism; Overview; Signal transduction; Cancers; Endocrine system	              Overview	               01200 Carbon metabolism	COG1071	C
LFTS_02028	62.3978918152506	-0.255984441336186	0.328355943553765	-0.779594358992533	0.435629677318995	0.617993776226542	777	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_02378	1288.86136421583	0.140727210558093	0.180517419444611	0.779576901725395	0.435639956162834	0.617993776226542	750	cytochrome c-type biogenesis protein	Cytochrome c	K06196	NA	              Overview	               01200 Carbon metabolism	COG0785	CO
LFTS_01818	1.36934754977874	-0.253605808456366	0.325409675630012	-0.779343170928677	0.43577759039627	0.617993776226542	207	putative transcriptional regulator (AbrB)	NA	NA	NA	NA	NA	NA	NA
LFTS_00020	187.950078856765	0.166857962958915	0.214412197485506	0.778211150838068	0.436444544143936	0.618586737024985	489	transcriptional regulator%2C AsnC family	NA	K03719	NA	              Cell growth and death	               04112 Cell cycle - Caulobacter	COG1522	K
LFTS_01801	568.911256897513	0.134296105662919	0.172996528711727	0.77629364394186	0.437575625121525	0.619709394159233	1320	Transposase	NA	K07497	NA	              Overview	               01200 Carbon metabolism	COG2801	X
LFTS_01819	6.99638155838566	0.336905927124523	0.434144055729942	0.776023356021934	0.43773519555254	0.619709394159233	318	PIN domain-containing protein	NA	K07062	NA	              Membrane transport	               02010 ABC transporters	COG1487	R
LFTS_01848	159.456975289332	-0.190201414360186	0.245403861986657	-0.775054690746995	0.438307343359681	0.619935659861595	387	homoserine dehydrogenase	NA	K00010	 Biosynthesis of other secondary metabolites; Carbohydrate metabolism	              Carbohydrate metabolism	               00562 Inositol phosphate metabolism	COG0673	R
LFTS_00666	951.435503279736	-0.130325416419236	0.168181695669372	-0.774908445895575	0.438393761076703	0.619935659861595	2808	Excinuclease ABC subunit A	NA	K03701	 Replication and repair	              Replication and repair	               03420 Nucleotide excision repair	COG0178	L
LFTS_01266	326.404002723763	0.132557803164898	0.171649802191259	0.772257243950661	0.439962083334013	0.621565528075728	1227	HTH-type transcriptional regulator / antitoxin HigA	NA	NA	NA	NA	NA	NA	NA
LFTS_00195	568.084014688065	-0.116139120004909	0.150416891881343	-0.772114877207577	0.440046391558037	0.621565528075728	1029	epoxyqueuosine reductase	NA	K14120	NA	              Signal transduction	               02020 Two-component system	COG1145	C
LFTS_02117	281.326375245609	0.137542589852678	0.178817436645102	0.769178847617964	0.441787145635376	0.623669985263796	606	methylthioribulose-1-phosphate dehydratase	NA	K08964	 Amino acid metabolism	              Amino acid metabolism	               00270 Cysteine and methionine metabolism	COG0235	G
LFTS_01922	4207.25604693081	-0.0985605839257816	0.128450167956845	-0.767305994951245	0.442899604921053	0.624885594684301	696	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01711	210.839973313634	0.330139252071038	0.431465239992717	0.76515839856905	0.444177228704308	0.625864915695915	459	hypothetical protein	NA	K13990	 Metabolism of cofactors and vitamins; Amino acid metabolism	              Amino acid metabolism	               00340 Histidine metabolism	NA	
LFTS_00231	285.174109860569	-0.148784198014753	0.194502693659211	-0.764946722411146	0.444303270490213	0.625864915695915	291	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00095	786.929860051862	-0.112466637914854	0.147040208315735	-0.764869957701345	0.444348984796175	0.625864915695915	1560	phenylalanyl-tRNA synthetase%2C alpha subunit	NA	K01889	 Translation	              Translation	               00970 Aminoacyl-tRNA biosynthesis	COG0016	J
LFTS_02377	653.880083892677	0.135318251316928	0.177303022797396	0.763203295589362	0.445342163673072	0.626558866578781	1251	geranylgeranyl reductase family protein	NA	K10960	 Metabolism of terpenoids and polyketides; Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00860 Porphyrin and chlorophyll metabolism	COG0644	C
LFTS_01069	6.05147675125339	-0.331016167734033	0.433795381160142	-0.763069829947852	0.445421751728017	0.626558866578781	789	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00368	294.674341818279	-0.135920865905349	0.178233655982656	-0.762599325901589	0.445702386731711	0.626558866578781	975	PD-(D/E)XK nuclease superfamily protein	NA	K07465	NA	              Overview	               01230 Biosynthesis of amino acids	COG2887	L
LFTS_01480	424.001042310928	0.132560560378843	0.173883614862197	0.762352223260927	0.445849812943629	0.626558866578781	1482	starch synthase	NA	K00703	 Carbohydrate metabolism; Cellular community - prokaryotes	              Carbohydrate metabolism	               00500 Starch and sucrose metabolism	COG0297	G
LFTS_01074	69.0563763088387	0.20566683641816	0.271061527031381	0.758745952148163	0.448004542602275	0.628892374496313	2010	hypothetical protein	NA	K14440	NA	              Energy metabolism	               00190 Oxidative phosphorylation	NA	
LFTS_00385	26.1480907318156	-0.276950261649721	0.365019942066596	-0.758726386513954	0.448016249088081	0.628892374496313	378	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_02372	733.853005157978	-0.136777940045002	0.180560349241021	-0.757519248383953	0.448738838505657	0.629551214743264	477	ribose 5-phosphate isomerase B	NA	K01808	 Carbohydrate metabolism; Overview; Energy metabolism	              Overview	               01200 Carbon metabolism	COG0698	G
LFTS_00430	496.660234269079	-0.113946918979726	0.150724993340403	-0.755992197806129	0.449653873601485	0.63005826962417	366	helix-turn-helix protein	NA	K15773	NA	              Overview	               01210 2-Oxocarboxylic acid metabolism	COG1396	K
LFTS_02070	405.774561844846	-0.182242114349225	0.241134933023929	-0.755768200251352	0.449788185721386	0.63005826962417	546	DNA-binding transcriptional regulator%2C MarR family	NA	K15973	NA	              Drug resistance	               01501 beta-Lactam resistance	COG1846	K
LFTS_01484	2889.94243040671	-0.102578723951043	0.135749445253026	-0.755647463308928	0.449860590741312	0.63005826962417	1422	membrane-bound lytic murein transglycosylase D	NA	K08307	NA	              Energy metabolism	               00190 Oxidative phosphorylation	COG0741	M
LFTS_01826	409.142708381592	-0.167076088374855	0.221315567945361	-0.754922439148534	0.450295521106459	0.630312311638884	1686	dihydroxy-acid dehydratase	NA	K01687	 Metabolism of cofactors and vitamins; Amino acid metabolism; Overview	              Overview	               01210 2-Oxocarboxylic acid metabolism	COG0129	EG
LFTS_01909	778.561479480241	-0.120490232051839	0.159878647197122	-0.753635548987855	0.451068092231574	0.631038422784296	1386	dihydrolipoamide dehydrogenase	Mercury resistance	K00520	NA	              Signal transduction	               02020 Two-component system	COG1249	C
LFTS_00191	265.144911382219	-0.145608254152678	0.194160902193044	-0.74993601960042	0.453293239464728	0.633794709397814	630	lipoate-protein ligase A	NA	K03800	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00785 Lipoic acid metabolism	COG0095	H
LFTS_02031	36.9429029548892	0.241023325560049	0.322258651040905	0.747918868218236	0.454509095912901	0.635137499965976	177	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01134	122.989490448053	-0.186166955798793	0.249323658647189	-0.746687886777055	0.455251983323948	0.635748152089599	2553	CRISPR-associated endonuclease/helicase Cas3	NA	K07012	NA	              Membrane transport	               02010 ABC transporters	COG1203	V
LFTS_01083	32.4719811214813	0.258080193115581	0.345790942232717	0.74634746488499	0.455457545805139	0.635748152089599	330	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_02188	552.357296083914	-0.125073321642402	0.167878601135614	-0.745022419750605	0.456258166583578	0.636508306468448	963	farnesyl-diphosphate farnesyltransferase	NA	K02291	 Metabolism of terpenoids and polyketides	              Metabolism of terpenoids and polyketides	               00906 Carotenoid biosynthesis	COG1562	I
LFTS_01469	11.397411928806	0.314412442715771	0.422259656253163	0.744595033079047	0.456516571495821	0.636511607817505	1158	Conjugal transfer protein	NA	K03204	 Membrane transport	              Membrane transport	               03070 Bacterial secretion system	COG3504	U
LFTS_02367	210.672270779358	0.154750588570155	0.208411578842781	0.742523949146287	0.457769947003953	0.637243431771037	879	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00307	173.686594392428	-0.169505669218863	0.228347043337411	-0.742316023634242	0.457895885647056	0.637243431771037	1206	methionine-gamma-lyase	NA	K01761	 Amino acid metabolism; Metabolism of other amino acids	              Amino acid metabolism	               00270 Cysteine and methionine metabolism	COG0626	E
LFTS_00510	570.84250764714	-0.116484159038388	0.156955284243988	-0.742148692855173	0.457997250536819	0.637243431771037	894	PAS domain S-box-containing protein/diguanylate cyclase (GGDEF) domain-containing protein	Putative diguanylate cyclases (GGDEF domain-containing proteins)	NA	NA	NA	NA	NA	NA
LFTS_01147	162.974842804953	0.14893908455542	0.200717350984954	0.742033928928167	0.458066778992294	0.637243431771037	420	hypothetical protein	NA	K07458	NA	              Metabolism of cofactors and vitamins	               00860 Porphyrin and chlorophyll metabolism	COG3727	L
LFTS_01744	673.13148608467	-0.116352349608895	0.156925116611743	-0.741451414031882	0.458419780491435	0.637377837976347	756	putative proteasome-type protease	NA	K07395	NA	              Folding, sorting and degradation	               04122 Sulfur relay system	COG3484	O
LFTS_00292	287.644772146853	-0.138580057436338	0.187127213197517	-0.740566030286911	0.458956611221418	0.637626071312518	534	Holliday junction endonuclease RuvC	NA	K01159	 Replication and repair	              Replication and repair	               03440 Homologous recombination	COG0817	L
LFTS_02369	991.458565976438	-0.109942396198992	0.148508386183802	-0.740311029054755	0.459111290285361	0.637626071312518	654	dTMP kinase	NA	K00943	 Nucleotide metabolism	              Nucleotide metabolism	               00240 Pyrimidine metabolism	COG0125	F
LFTS_01697	1667.61601340447	-0.10448808949524	0.141375832788356	-0.739080275846453	0.459858253108047	0.63830687729012	1248	hypothetical protein	NA	K15201	NA	              Overview	               01200 Carbon metabolism	NA	
LFTS_01092	4.51978030971257	0.310674590061361	0.421011664290321	0.737923949411354	0.46056066454827	0.63874921259934	516	hypothetical protein	NA	K03497	NA	              Amino acid metabolism	               00310 Lysine degradation	COG1475	D
LFTS_02321	801.29865107834	0.142502460507662	0.193193558258851	0.737614969111597	0.460748456418828	0.63874921259934	705	putative ABC transport system ATP-binding protein	NA	K05685	 Membrane transport	              Membrane transport	               02010 ABC transporters	COG0577;COG1136	VM
LFTS_02233	309.718719327196	0.126745575539163	0.171908020912467	0.737287154295726	0.460947742318269	0.63874921259934	432	hypothetical protein	NA	K03704	NA	              Metabolism of cofactors and vitamins	               00770 Pantothenate and CoA biosynthesis	COG1278	K
LFTS_01347	1119.36878384101	-0.130660296078561	0.177549418239763	-0.735909457625579	0.461785801217164	0.639554040014412	1407	tRNA-2-methylthio-N6-dimethylallyladenosine synthase	NA	K06168	NA	              Metabolism of cofactors and vitamins	               00860 Porphyrin and chlorophyll metabolism	COG0621	J
LFTS_01175	12.8067150807675	-0.302878407669529	0.412736058272233	-0.733830741460819	0.463051902100983	0.640299520751309	1161	dTDP-4-amino-4%2C6-dideoxygalactose transaminase	NA	K13010	 Carbohydrate metabolism	              Carbohydrate metabolism	               00520 Amino sugar and nucleotide sugar metabolism	COG0399	M
LFTS_02468	494.939114723458	-0.108227151541469	0.147524296054967	-0.733622558694628	0.463178808224155	0.640299520751309	639	GTP-binding protein	NA	K03978	NA	              Nucleotide metabolism	               00230 Purine metabolism	COG0218	D
LFTS_00443	521.944191222611	-0.157463496509596	0.214661330732048	-0.733543838438933	0.463226800351966	0.640299520751309	1101	DNA repair photolyase	NA	K03716	NA	              Folding, sorting and degradation	               03050 Proteasome	COG1533	L
LFTS_00413	2680.12817568562	-0.117575246649582	0.160329584217011	-0.733334694428197	0.463354319320839	0.640299520751309	1077	ATP-binding protein involved in chromosome partitioning	NA	K03593	NA	              Replication and repair	               03030 DNA replication	COG0489	D
LFTS_00816	220.183807278778	-0.146616015276175	0.200198362296025	-0.732353719554307	0.463952698815672	0.640463606659906	258	hypothetical protein	NA	K08992	NA	              Amino acid metabolism	               00270 Cysteine and methionine metabolism	COG3771	S
LFTS_02236	171.881219119111	0.151877561062988	0.207567514674207	0.731701978035298	0.464350488841798	0.640463606659906	951	lipoic acid synthetase	NA	K03644	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00785 Lipoic acid metabolism	COG0320	H
LFTS_01017	140.136219031724	0.156297714803204	0.213692066206673	0.731415618640891	0.464525328122121	0.640463606659906	201	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00041	962.202476853051	-0.103157391674913	0.141043422747465	-0.731387466820157	0.464542518444467	0.640463606659906	2256	PAS/PAC sensor signal transduction histidine kinase	NA	K13598	 Signal transduction	              Signal transduction	               02020 Two-component system	COG5000	T
LFTS_01141	4.75683952200472	0.30902963754281	0.422732165967658	0.731029390288822	0.464761201293029	0.640463606659906	615	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01040	30.6895965512768	0.257817341633167	0.353114193403752	0.730124550214209	0.465314056144132	0.64087021804671	354	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01428	13.9034409840146	0.304967704469886	0.420520611795572	0.725214640889326	0.468320362283182	0.644653610540416	312	Transposase	NA	K07487	NA	              Overview	               01230 Biosynthesis of amino acids	COG3666	X
LFTS_00609	501.975820763348	0.124299101412837	0.17157507909375	0.724458948638564	0.46878402095671	0.644934740508235	693	hypothetical protein	NA	K06997	NA	              Cell growth and death	               04112 Cell cycle - Caulobacter	COG0325	R
LFTS_01948	1021.90541229991	0.104480387704114	0.144343874830657	0.723829728325425	0.469170275883189	0.645109129339384	1335	dihydrofolate synthase / folylpolyglutamate synthase	NA	K11754	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00790 Folate biosynthesis	COG0285	H
LFTS_01685	1217.40134755663	0.0954938951930257	0.132143540905033	0.722652764857069	0.469893242276133	0.645408749342545	948	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01749	10.1421142245781	-0.307502085049567	0.425778825122662	-0.722210844940397	0.470164856691164	0.645408749342545	351	addiction module antidote protein%2C HigA family	NA	K07110	NA	              Folding, sorting and degradation	               04122 Sulfur relay system	COG3800	R
LFTS_01325	850.057147461174	0.101331386775627	0.140385339570655	0.721808894614864	0.470411980146457	0.645408749342545	1281	2-C-methyl-D-erythritol 2%2C4-cyclodiphosphate synthase	NA	K12506	 Metabolism of terpenoids and polyketides	              Metabolism of terpenoids and polyketides	               00900 Terpenoid backbone biosynthesis	COG1211;COG0245	I
LFTS_01695	1000.21915321657	0.116039283831128	0.160767095463166	0.721785036277612	0.470426650767776	0.645408749342545	1389	putative radical SAM enzyme	NA	K08669	 Cell growth and death; Neurodegenerative diseases	              Cell growth and death	               04210 Apoptosis	NA	
LFTS_00677	1372.10162692272	-0.105287415101312	0.146107800506549	-0.720614606039415	0.471146664809416	0.645811039512216	855	hypothetical protein	NA	K09769	NA	              Xenobiotics biodegradation and metabolism	               00627 Aminobenzoate degradation	COG1692	R
LFTS_01100	64.9270524750311	-0.209430299614509	0.290688132168283	-0.720463880146531	0.471239431084135	0.645811039512216	1320	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00634	179.705570507165	-0.201801961861377	0.280725258861838	-0.718859295667071	0.472227618434678	0.646808737977196	303	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00309	21.6253322992362	-0.272161765229918	0.380131764367835	-0.715966911322255	0.474011780533201	0.648387509170658	1530	Putative beta-barrel porin-2%2C OmpL-like. bbp2	NA	K09993	 Cell growth and death	              Cell growth and death	               04110 Cell cycle	NA	
LFTS_02093	783.713492212635	0.103476719214566	0.144562838758089	0.715790587010563	0.47412066555008	0.648387509170658	1392	DNA-binding transcriptional response regulator%2C NtrC family%2C contains REC%2C AAA-type ATPase%2C and a Fis-type DNA-binding domains	NA	K02481	NA	              Overview	               01210 2-Oxocarboxylic acid metabolism	COG2204	T
LFTS_01088	21.6357572855848	-0.269257245249903	0.376669146312013	-0.714837538158394	0.474709436770941	0.648387509170658	690	YqaJ-like viral recombinase domain protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01683	658.252765311776	0.126645133309215	0.177169018579889	0.714826634613363	0.474716175047307	0.648387509170658	225	hypothetical protein	NA	K02664	NA	              Metabolism of cofactors and vitamins	               00860 Porphyrin and chlorophyll metabolism	COG3167	NW
LFTS_01735	94.1201180940553	0.231607206675726	0.324177969494575	0.714444621381349	0.474952288365298	0.648387509170658	339	hypothetical protein	NA	K02016	 Membrane transport	              Membrane transport	               02010 ABC transporters	COG0614	P
LFTS_00259	416.76788624624	-0.124741791932949	0.174612560418844	-0.714391860664152	0.474984903578987	0.648387509170658	873	N-acetylglutamate kinase	NA	K00930	 Overview; Amino acid metabolism	              Overview	               01210 2-Oxocarboxylic acid metabolism	COG0548	E
LFTS_01603	952.233009902245	0.171956092502919	0.241017904699424	0.713457752100898	0.475562547127964	0.648387509170658	333	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_02407	1532.13888173138	-0.118607863997865	0.166274146165872	-0.713327157185	0.475643336428457	0.648387509170658	450	RDD family protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01427	49.5486809962785	0.210048911087094	0.294519874378583	0.713190957079835	0.475727601257956	0.648387509170658	363	Transposase DDE domain group 1	NA	K01998	 Cellular community - prokaryotes; Membrane transport	              Membrane transport	               02010 ABC transporters	COG0559	E
LFTS_01205	56.6723822914965	-0.20430304573452	0.287364388821581	-0.710954640456052	0.477112344665681	0.649918514432265	1602	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01090	322.303516127427	0.132770882949421	0.18797371408812	0.706326858483943	0.479984894400828	0.653473410449321	1011	helix-turn-helix protein	NA	K07729	NA	              Amino acid metabolism	               00310 Lysine degradation	COG1476	K
LFTS_02363	485.209868072389	-0.125139336822038	0.177317432240578	-0.705736233830934	0.480352183428237	0.653615505201203	864	4-hydroxybenzoate polyprenyltransferase	NA	K06125	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00130 Ubiquinone and other terpenoid-quinone biosynthesis	COG0382	H
LFTS_00612	519.994160585487	0.116077582143612	0.165224526845186	0.702544497236634	0.482339661951849	0.655889589306335	528	cell division initiation protein	NA	K04074	NA	              Overview	               01230 Biosynthesis of amino acids	COG3599	D
LFTS_00244	312.049163648326	0.128536746726594	0.183117014236072	0.701937759649605	0.482717979427053	0.655889589306335	1068	A/G-specific DNA-adenine glycosylase	NA	K03575	 Replication and repair	              Replication and repair	               03410 Base excision repair	COG1194	L
LFTS_00923	2175.03528489799	0.134887968940686	0.192207712106378	0.701782293033235	0.482814943053336	0.655889589306335	312	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_02065	152.329194133917	-0.143827440984791	0.205394949684406	-0.700248186266435	0.483772323634761	0.656831237878764	1095	hypothetical protein	NA	K07404	 Carbohydrate metabolism; Overview	              Overview	               01200 Carbon metabolism	COG2706	G
LFTS_00643	1668.21407861107	0.110126537189895	0.157453486710763	0.699422664371949	0.484287927932945	0.657172373821671	1209	Site-specific recombinase XerD	NA	K04763	NA	              Nucleotide metabolism	               00230 Purine metabolism	COG0582	LX
LFTS_00803	5033.19314646628	0.0875636002368649	0.12539090572869	0.698324968050932	0.484973988096138	0.657744317734315	1449	NusA antitermination factor	NA	K02600	NA	              Translation	               03010 Ribosome	COG0195	K
LFTS_01071	13.0772680437798	-0.299201499463264	0.429563722475364	-0.696524133227809	0.486100649133113	0.658912875542486	609	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00704	211.429797087478	0.155883403762116	0.224382214732708	0.694722636318615	0.487229139257752	0.660082637708322	339	nitrogen regulatory protein P-II family protein	Nitrate/nitrite regulation	K04751	 Signal transduction	              Signal transduction	               02020 Two-component system	COG0347	TE
LFTS_01174	9.99726654478371	-0.29598398721987	0.426537886878853	-0.693921914851931	0.487731179397899	0.660402893237024	1164	cysteine desulfurase	Nitrogenase genes	K04487	 Metabolism of cofactors and vitamins; Folding, sorting and degradation	              Metabolism of cofactors and vitamins	               00730 Thiamine metabolism	COG1104	E
LFTS_02219	3.18592500041971	-0.279368501402843	0.402946846627025	-0.693313531899733	0.488112812776371	0.660559854415928	93	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01631	1844.55603776131	0.104291948939549	0.15082291701972	0.691486088456388	0.489260120159427	0.661752262631303	1287	putative arabinose efflux permease%2C MFS family	Lipopolysaccharide synthesis	K08217	NA	              Carbohydrate metabolism	               00630 Glyoxylate and dicarboxylate metabolism	COG0477	GEPR
LFTS_02097	1272.04115931162	-0.096452810783743	0.139714030126503	-0.690358804311995	0.489968576413685	0.662350125592398	1284	enolase	NA	K01689	 Overview; Signal transduction; Energy metabolism; Carbohydrate metabolism; Folding, sorting and degradation	              Overview	               01200 Carbon metabolism	COG0148	G
LFTS_01269	62.269464899683	-0.204940908574982	0.297711753483651	-0.688387025963475	0.491209091771995	0.663218135672265	282	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01359	1309.65303403927	-0.123874451920524	0.179964051566995	-0.688328868137366	0.491245706507559	0.663218135672265	813	acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase	NA	K00677	 Glycan biosynthesis and metabolism; Drug resistance	              Glycan biosynthesis and metabolism	               00540 Lipopolysaccharide biosynthesis	COG1043	M
LFTS_00418	1598.79715918108	-0.111664658944201	0.16228764163675	-0.688066311260727	0.491411024098275	0.663218135672265	678	Co-chaperone protein HscB	NA	K04082	NA	              Replication and repair	               03030 DNA replication	COG1076	O
LFTS_00622	8779.28355596681	-0.093561800966646	0.13691676947235	-0.683348002784571	0.494386968292877	0.666701047604436	1440	hopanoid biosynthesis associated radical SAM protein HpnJ	NA	K04034	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00860 Porphyrin and chlorophyll metabolism	COG1032	R
LFTS_00046	242.629460216712	0.13234989724368	0.193789852812567	0.682955765344889	0.494634794510583	0.666701047604436	198	hypothetical protein	NA	K02710	 Energy metabolism	              Energy metabolism	               00195 Photosynthesis	NA	
LFTS_00754	498.851935272728	-0.123600553081805	0.181061203251361	-0.68264515457911	0.494831093898366	0.666701047604436	810	arsenate reductase (thioredoxin)	Arsenic resistance	K03741	NA	              Energy metabolism	               00190 Oxidative phosphorylation	COG0394	T
LFTS_02144	110.265631159822	0.152349664124949	0.223296221714324	0.682276049972126	0.495064414271033	0.666701047604436	969	Sigma-54 interaction domain-containing protein	NA	K02481	NA	              Signal transduction	               02020 Two-component system	COG2204	T
LFTS_01323	767.657728037465	0.0994805680980604	0.147652207566381	0.673749277018675	0.500470727554619	0.673591543885955	1362	putative inorganic carbon (hco3(-)) transporter	Lipopolysaccharide synthesis	K02847	 Glycan biosynthesis and metabolism	              Glycan biosynthesis and metabolism	               00540 Lipopolysaccharide biosynthesis	COG3307	M
LFTS_02355	1611.85251020465	0.0948687489085081	0.140949680033703	0.673068210483511	0.500903896996518	0.673591543885955	1404	argininosuccinate lyase	NA	K01755	 Amino acid metabolism; Overview	              Overview	               01230 Biosynthesis of amino acids	COG0165	E
LFTS_00583	916.747358586094	-0.11209087241953	0.166639495910681	-0.672654893769064	0.501166870024427	0.673591543885955	603	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00389	45.0136003609303	-0.226121814965071	0.336240134174726	-0.672500965775749	0.501264825498398	0.673591543885955	786	hypothetical protein	NA	K06297	NA	              Folding, sorting and degradation	               04141 Protein processing in endoplasmic reticulum	NA	
LFTS_02481	2593.55864824508	0.0902711120712265	0.134332475649086	0.671997680643063	0.50158517286862	0.673657882091512	993	octaprenyl-diphosphate synthase	NA	K02523	 Metabolism of terpenoids and polyketides	              Metabolism of terpenoids and polyketides	               00900 Terpenoid backbone biosynthesis	COG0142	H
LFTS_00394	1774.35629255278	-0.105004740274127	0.156484460115424	-0.671023437066371	0.502205599130787	0.674126954340787	1446	zinc protease	NA	K07263	NA	              Carbohydrate metabolism	               00520 Amino sugar and nucleotide sugar metabolism	COG0612	R
LFTS_00511	442.957379493597	-0.104460992329607	0.156053150903437	-0.669393675967784	0.503244384660162	0.674887930246122	2244	PAS domain S-box-containing protein/diguanylate cyclase (GGDEF) domain-containing protein	Putative diguanylate cyclases (GGDEF domain-containing proteins)	K13069	NA	              Signal transduction	               02020 Two-component system	COG2199	T
LFTS_01535	767.812166980561	0.095745603086131	0.143057140604448	0.669282237024901	0.503315455622007	0.674887930246122	909	prephenate dehydrogenase	NA	K04517	 Overview; Amino acid metabolism; Biosynthesis of other secondary metabolites	              Overview	               01230 Biosynthesis of amino acids	COG0287	E
LFTS_02198	524.763277820277	0.103381968804793	0.154994050519721	0.66700604609103	0.504768271464706	0.676163490761476	711	outer membrane lipoprotein	NA	K07285	NA	              Carbohydrate metabolism	               00630 Glyoxylate and dicarboxylate metabolism	COG3065	M
LFTS_00514	8980.91264165192	-0.165250679487242	0.247774580670678	-0.666939599049833	0.504810715548391	0.676163490761476	858	DSF synthase	Quorum sensing	K13816	 Cellular community - prokaryotes; Signal transduction	              Signal transduction	               02020 Two-component system	COG1024	I
LFTS_02270	701.649419085948	0.125630807458757	0.188557689997603	0.666272520947587	0.505236926302258	0.676369950881752	618	ATP phosphoribosyltransferase	NA	K00765	 Overview; Amino acid metabolism	              Overview	               01230 Biosynthesis of amino acids	COG0040	E
LFTS_02375	698.838146599508	0.0945971960494229	0.142084009468194	0.665783548785612	0.505549461635631	0.676424091295037	1986	replication restart DNA helicase PriA	NA	K04066	 Replication and repair	              Replication and repair	               03440 Homologous recombination	COG1198	L
LFTS_00594	791.424352920831	-0.110642077546737	0.166383757422071	-0.664981241324344	0.506062491300189	0.676746290141082	1737	peptidoglycan synthetase FtsI	NA	K03587	 Drug resistance; Glycan biosynthesis and metabolism	              Glycan biosynthesis and metabolism	               00550 Peptidoglycan biosynthesis	COG0768	DM
LFTS_01158	43.8566717049337	0.199869511970684	0.301926530634584	0.661980620088607	0.507983641963717	0.67895017952785	1140	Transposase	NA	K07485	NA	              Cellular community - prokaryotes	               02026 Biofilm formation - Escherichia coli	COG3464	X
LFTS_02373	2522.80647895675	-0.0764980137848905	0.116670186106949	-0.655677481432716	0.512031660698427	0.683802308241066	1245	glycine hydroxymethyltransferase	NA	K00600	 Carbohydrate metabolism; Overview; Amino acid metabolism; Metabolism of cofactors and vitamins; Energy metabolism; Drug resistance; Metabolism of other amino acids	              Overview	               01200 Carbon metabolism	COG0112	E
LFTS_01576	778.749837082251	0.089780940484839	0.137025559524029	0.655213091606424	0.512330566572917	0.683802308241066	903	glycyl-tRNA synthetase alpha chain	NA	K14164	 Translation	              Translation	               00970 Aminoacyl-tRNA biosynthesis	NA	
LFTS_00366	157.66344084337	-0.137125601142527	0.209337858353517	-0.65504444452163	0.512439139281217	0.683802308241066	201	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01497	362.702613942622	0.114676904779794	0.175410343707505	0.653763639908351	0.513264095277101	0.68451945697949	642	Peptidase_C39 like family protein	NA	K06992	NA	              Overview	               01200 Carbon metabolism	COG3271	R
LFTS_02374	1045.45313724118	0.112217169284771	0.171755206128376	0.653355271227682	0.513527267605289	0.68451945697949	468	transcriptional repressor NrdR	NA	K07738	NA	              Replication and repair	               03440 Homologous recombination	COG1327	K
LFTS_01761	36.7825209168855	-0.213011180760406	0.327248023021001	-0.650916631348865	0.515100304867834	0.68624831613153	246	prevent-host-death family protein	NA	K15656	 Cellular community - prokaryotes; Metabolism of terpenoids and polyketides	              Metabolism of terpenoids and polyketides	               01054 Nonribosomal peptide structures	NA	
LFTS_00922	1844.54097833689	-0.110365582257309	0.169770586911048	-0.650086591943843	0.515636289577013	0.686594438076301	204	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01763	24.6656653074528	-0.242960150094482	0.375058265695516	-0.647793082613263	0.517118790045045	0.688199845852239	192	Putative restriction endonuclease	NA	NA	NA	NA	NA	NA	NA
LFTS_00132	313.573447052735	-0.10507439736617	0.162316247154271	-0.647343683755233	0.517409535179172	0.688218354443779	714	uracil-DNA glycosylase%2C family 4	NA	K02334	NA	              Signal transduction	               02020 Two-component system	COG1573	L
LFTS_02061	19.8705021867143	-0.249912983044855	0.387402723804305	-0.645098673005453	0.518863243753715	0.689146593904476	420	biopolymer transport protein ExbD	NA	K03559	NA	              Replication and repair	               03440 Homologous recombination	COG0848	U
LFTS_01042	18.2381279123186	0.247064140350281	0.383277271009061	0.644609422572413	0.519180327131736	0.689146593904476	762	transposase%2C IS605 OrfB family%2C central region	NA	K07496	NA	              Folding, sorting and degradation	               03018 RNA degradation	COG0675	X
LFTS_01232	227.483340972276	0.147385103077706	0.228652866519922	0.64458016783649	0.519199290305867	0.689146593904476	684	putative isomerase YddE	NA	K06998	 Cellular community - prokaryotes;NA	              Biosynthesis of other secondary metabolites	               00405 Phenazine biosynthesis	COG0384	R
LFTS_00906	1443.34105279549	-0.086295375497409	0.133883852494025	-0.644554021189822	0.519216239092149	0.689146593904476	1008	cytoskeleton protein RodZ	NA	K15539	NA	              Carbohydrate metabolism	               00030 Pentose phosphate pathway	COG1426	D
LFTS_01698	1112.97695514326	-0.0958279304556059	0.148953751259117	-0.643340161933253	0.520003401597589	0.689823082375457	654	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01900	153.141677910745	0.13678639866714	0.21283116748321	0.64269909470816	0.520419368561267	0.690006693463098	522	hypothetical protein	NA	K09705	NA	              Nucleotide metabolism	               00230 Purine metabolism	COG3542	R
LFTS_01573	241.112072844873	-0.128345597383585	0.200586978670418	-0.6398500951274	0.522270060895038	0.69209134935238	633	riboflavin synthase alpha chain	NA	K00793	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00740 Riboflavin metabolism	COG0307	H
LFTS_02242	572.051329783779	0.0914156452935078	0.143685441507741	0.636220652101228	0.524632614223728	0.694851720277137	720	putative glutamine amidotransferase	NA	K07010	NA	              Metabolism of other amino acids	               00471 D-Glutamine and D-glutamate metabolism	COG2071	E
LFTS_00595	570.45341377468	0.0950082947020066	0.149595420088044	0.635101627082496	0.525362135942932	0.695319341033948	1545	UDP-N-acetylmuramoylalanyl-D-glutamate--2%2C 6-diaminopimelate ligase	NA	K01928	 Amino acid metabolism; Glycan biosynthesis and metabolism	              Amino acid metabolism	               00300 Lysine biosynthesis	COG0769	M
LFTS_00051	1349.84824268497	0.0935923681406842	0.147433925235541	0.634808901622614	0.525553056941827	0.695319341033948	2373	penicillin-binding protein 1A	NA	K05366	 Drug resistance; Glycan biosynthesis and metabolism	              Glycan biosynthesis and metabolism	               00550 Peptidoglycan biosynthesis	COG0744	M
LFTS_00496	761.896704631291	0.132272869394654	0.208514221312781	0.634358983103788	0.525846571356021	0.695319341033948	1917	maltooligosyl trehalose hydrolase	NA	K01236	 Carbohydrate metabolism	              Carbohydrate metabolism	               00500 Starch and sucrose metabolism	COG0296	G
LFTS_01842	985.736210329373	0.268977097117084	0.424278332153549	0.633963784461514	0.526104457154005	0.695319341033948	1038	hypothetical protein	NA	K05802	NA	              Nucleotide metabolism	               00230 Purine metabolism	COG3264	M
LFTS_01010	496.151148815682	0.125614398502431	0.198370511892281	0.633231206111126	0.52658267005797	0.695581571606862	207	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00869	663.774749572223	0.0977391006971387	0.155130216491753	0.630045537919651	0.528664790748293	0.697949814848582	768	BirA family transcriptional regulator%2C biotin operon repressor / biotin-[acetyl-CoA-carboxylase] ligase	NA	K03524	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00780 Biotin metabolism	COG1654;COG0340	KH
LFTS_00382	2.98723814088881	0.223029849893394	0.354223960571017	0.629629485068897	0.528937027825715	0.697949814848582	177	DNA binding domain-containing protein%2C excisionase family	NA	K07450	NA	              Folding, sorting and degradation	               03018 RNA degradation	COG2452	X
LFTS_02291	48.3915530632127	0.204271383854717	0.32467907619104	0.629148592669165	0.529251780416555	0.69799465576422	339	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_02507	172.383871408408	0.124810764162565	0.199263366234103	0.626360813436887	0.531078306362304	0.700032168407575	456	large conductance mechanosensitive channel	NA	K03282	NA	              Membrane transport	               02010 ABC transporters	COG1970	M
LFTS_01774	124.13643529999	-0.154126259284666	0.24645826985705	-0.625364526717089	0.531731838473257	0.700522178295981	1104	extracellular solute-binding protein	NA	K02048	 Energy metabolism; Membrane transport	              Energy metabolism	               00920 Sulfur metabolism	COG1613	P
LFTS_01855	189.804052770593	-0.135739933069115	0.217773224996452	-0.623308641690579	0.533081720066338	0.701666719095209	432	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01408	75.3319591776733	0.164046136176256	0.263239637434229	0.623181743354452	0.533165097494308	0.701666719095209	588	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00026	750.416801040892	0.0886591847747968	0.143038723017417	0.619826456112877	0.535372048812673	0.704198366850955	3168	ATP-dependent helicase IRC3	NA	K01153	NA	              Cell growth and death	               04112 Cell cycle - Caulobacter	COG0610	V
LFTS_00053	3272.45701835958	0.0727650048550284	0.117601494396227	0.618742178648394	0.536086218932535	0.704370355826225	1200	phosphoglycerate kinase	NA	K15330	NA	NA	NA	NA	
LFTS_01877	958.18112944271	0.10086366944526	0.163087146929094	0.618464859705421	0.536268954797783	0.704370355826225	1638	CTP synthase	NA	K01937	 Nucleotide metabolism	              Nucleotide metabolism	               00240 Pyrimidine metabolism	COG0504	F
LFTS_00081	60.0329794892182	-0.183665459183807	0.29707336527874	-0.618249498777772	0.536410885822688	0.704370355826225	1131	processive 1%2C2-diacylglycerol beta-glucosyltransferase	Lipopolysaccharide synthesis	K03715	 Lipid metabolism	              Lipid metabolism	               00561 Glycerolipid metabolism	NA	
LFTS_00246	7973.32210009419	0.101476555245292	0.164226057593782	0.617907759171184	0.536636143980237	0.704370355826225	528	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00596	523.833048056275	-0.10706730766598	0.173827018567786	-0.615941690469871	0.537933004625131	0.705699973349908	1488	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase	NA	K01929	 Amino acid metabolism; Glycan biosynthesis and metabolism; Drug resistance	              Amino acid metabolism	               00300 Lysine biosynthesis	COG0770	M
LFTS_01964	1324.8191477357	0.0896543731658362	0.145658660186395	0.615510077129009	0.538217916409464	0.705701339764729	567	cytochrome c oxidase cbb3-type subunit 1	Cytochrome cbb3 oxidase	K00404	 Energy metabolism; Signal transduction	              Energy metabolism	               00190 Oxidative phosphorylation	COG3278	C
LFTS_02517	698.24209628619	0.0882072263857638	0.143621352932603	0.614165126456903	0.539106215569808	0.706493438010829	876	ribosomal protein L11 methyltransferase	NA	K02687	NA	              Metabolism of cofactors and vitamins	               00860 Porphyrin and chlorophyll metabolism	COG2264	J
LFTS_01013	172.681867003969	0.120350949972857	0.19657953438418	0.612225226546994	0.540388753363231	0.707659150768721	627	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00672	1323.7851357564	0.0750646451951555	0.122662918394688	0.611958741708907	0.540565055233227	0.707659150768721	2061	soluble lytic murein transglycosylase	NA	K08309	NA	              Energy metabolism	               00190 Oxidative phosphorylation	COG0741	M
LFTS_01297	573.745335961894	0.124184349490784	0.203403047789628	0.61053337617253	0.541508541018375	0.708120094895473	1218	lipid-A-disaccharide synthase	Lipopolysaccharide synthesis	K00748	 Glycan biosynthesis and metabolism	              Glycan biosynthesis and metabolism	               00540 Lipopolysaccharide biosynthesis	COG0763	M
LFTS_00282	1110.81380022665	0.118412671472791	0.193952517073999	0.610524025463475	0.541514733204379	0.708120094895473	987	Thiamine biosynthesis protein (ThiI)	NA	K03151	 Metabolism of cofactors and vitamins; Folding, sorting and degradation	              Metabolism of cofactors and vitamins	               00730 Thiamine metabolism	COG0301	HJ
LFTS_01242	16.7689034722346	-0.244059320123988	0.400008033047	-0.610136047181111	0.541771689658564	0.708120094895473	1380	putative membrane protein	putative pel operon	K05310	 Glycan biosynthesis and metabolism	              Glycan biosynthesis and metabolism	               00563 Glycosylphosphatidylinositol(GPI)-anchor biosynthesis	NA	
LFTS_00526	118.959812643625	0.149407299750392	0.245450706606564	0.608705926399629	0.542719378106173	0.708986008393035	816	methyltransferase%2C FkbM family	NA	NA	NA	NA	NA	NA	NA
LFTS_01776	2569.65938173154	0.0891496538913446	0.146785560707524	0.607346209406651	0.543621177968076	0.70979109686378	1488	hypothetical protein	NA	K04034	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00860 Porphyrin and chlorophyll metabolism	COG1032	R
LFTS_01023	107.463654790034	0.145675710498217	0.240139161624072	0.606630378456415	0.544096235195444	0.710038446559514	465	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00107	429.356824757975	-0.0988963513781762	0.164136864966556	-0.602523701170528	0.546825591398282	0.712904223478331	693	nicotinate-nucleotide adenylyltransferase	NA	K00969	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00760 Nicotinate and nicotinamide metabolism	COG1057	H
LFTS_00412	1043.12356056227	0.123212074500198	0.20451382837906	0.602463292955569	0.546865790093796	0.712904223478331	258	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00774	1108.71004257244	0.100573762345993	0.167433940286766	0.600677271129967	0.548054960424867	0.714079995605985	963	GTP-binding protein Era	NA	K03595	NA	              Replication and repair	               03440 Homologous recombination	COG1159	J
LFTS_02169	1370.64384452233	0.0744651903110205	0.124059101950739	0.600239636915872	0.54834654115029	0.714085647616355	1182	1-deoxy-D-xylulose 5-phosphate reductoisomerase	NA	K00099	 Metabolism of terpenoids and polyketides	              Metabolism of terpenoids and polyketides	               00900 Terpenoid backbone biosynthesis	COG0743	I
LFTS_01636	530.802876728943	-0.121422828717695	0.202673657337223	-0.599105134396736	0.549102778024404	0.714696076528098	432	hypothetical protein	NA	K04925	NA	              Translation	               03010 Ribosome	NA	
LFTS_01814	713.210960824824	-0.135533903910046	0.226969008590489	-0.597147182127337	0.550409119235224	0.716021491584912	1512	undecaprenyl-phosphate galactose phosphotransferase	Lipopolysaccharide synthesis	K00996	NA	              Membrane transport	               02010 ABC transporters	COG2148	M
LFTS_02129	579.164210555918	0.102121331100762	0.171283030301213	0.596213944377178	0.551032311304341	0.716089504562204	792	TatD DNase family protein	NA	K03424	NA	              Metabolism of other amino acids	               00450 Selenocompound metabolism	COG0084	N
LFTS_01463	3.15407073130293	-0.230666251205058	0.386890072060745	-0.596206178091955	0.551037498884753	0.716089504562204	264	TrbC/VIRB2 family protein	NA	K03197	 Infectious diseases; Membrane transport	              Membrane transport	               03070 Bacterial secretion system	COG3838	U
LFTS_00308	78.3875658212541	-0.156610814954032	0.263120606907257	-0.595205433716688	0.551706158606902	0.71658386117908	435	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00633	306.929837718446	0.145193491882725	0.244190319624839	0.59459151413452	0.552116553760974	0.716676173322579	405	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00472	1462.20019072225	-0.128064917301547	0.215511620880649	-0.594236713446045	0.552353800517321	0.716676173322579	207	putative cobalt transporter subunit (CbtB)	NA	NA	NA	NA	NA	NA	NA
LFTS_01032	38.3367078917026	0.211741108236407	0.356815501811581	0.593419027932867	0.552900757777153	0.717011624326553	327	hypothetical protein	NA	K07070	NA	              Cell motility	               02040 Flagellar assembly	COG3529	R
LFTS_00363	140.042760573953	0.140990671186051	0.237965530217676	0.592483588093963	0.553526807521337	0.717449240614204	1326	anthranilate synthase component 1	NA	K01665	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00790 Folate biosynthesis	COG0147	EH
LFTS_01960	656.677815854791	-0.0946024515610709	0.160258027980801	-0.590313338763935	0.554980598347866	0.718958711564771	327	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00524	175.096689799708	-0.119057215296354	0.202101677845485	-0.589095630306338	0.555797124527845	0.719641485195949	1830	hypothetical protein	NA	K06147	NA	              Overview	               01200 Carbon metabolism	COG1132;COG2274;COG5265	VO
LFTS_00378	1938.32843080377	-0.0850843770204381	0.144648052987638	-0.588216538439751	0.55638695787722	0.720030180782285	2487	leucyl-tRNA synthetase	NA	K01869	 Translation	              Translation	               00970 Aminoacyl-tRNA biosynthesis	COG0495	J
LFTS_01875	312.65317042878	-0.0987452396839494	0.168436764049081	-0.586245171838944	0.557710769953231	0.721367832520152	999	arabinose-5-phosphate isomerase	NA	K06041	 Glycan biosynthesis and metabolism	              Glycan biosynthesis and metabolism	               00540 Lipopolysaccharide biosynthesis	COG0794;COG0517	GMT
LFTS_01445	200.712417623566	0.119369378589146	0.204406326277281	0.583980842291638	0.559233201259965	0.722960862367277	2145	Methyl-accepting chemotaxis protein	Chemotaxis	K03406	 Signal transduction; Cell motility	              Signal transduction	               02020 Two-component system	COG0840	NT
LFTS_01318	205.790360612397	-0.132971220003595	0.228742310869248	-0.581314490958355	0.561028515904441	0.724616048334705	288	hypothetical protein	NA	K01430	 Nucleotide metabolism; Amino acid metabolism; Xenobiotics biodegradation and metabolism	              Nucleotide metabolism	               00230 Purine metabolism	COG0831	E
LFTS_02509	1440.24051225751	-0.0718244872314312	0.123576747478271	-0.581213607714191	0.561096497604307	0.724616048334705	1128	cobalt-precorrin-5B (C1)-methyltransferase	NA	K02188	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00860 Porphyrin and chlorophyll metabolism	COG1903	H
LFTS_02513	550.46870072041	0.111542323731554	0.192135476556847	0.580539969663293	0.56155054094756	0.724825879956197	822	precorrin-3B C17-methyltransferase	NA	K05934	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00860 Porphyrin and chlorophyll metabolism	COG1010	H
LFTS_00538	87.6005920932247	0.15495309257654	0.268413750963946	0.577291930909135	0.563742263679719	0.727130482286473	1323	putative PEP-CTERM system histidine kinase	Extracellular polysaccharide production and export	K00936	NA	              Metabolism of terpenoids and polyketides	               00523 Polyketide sugar unit biosynthesis	NA	
LFTS_01101	43.7252779876185	0.182501918735164	0.316279499304459	0.577027341754713	0.563920985457892	0.727130482286473	1134	Competence protein ComGC	NA	NA	NA	NA	NA	NA	NA
LFTS_00304	184.27855017617	-0.143686394410938	0.249611190684228	-0.575640835721622	0.564857973311695	0.727961079135756	840	oligopeptide transport system permease protein	NA	K02034	 Cellular community - prokaryotes	              Cellular community - prokaryotes	               02024 Quorum sensing	COG1173	EP
LFTS_02502	648.548739388602	0.104538974717362	0.182704027787459	0.572176628962843	0.567202319078517	0.730603608927044	1338	tRNA modification GTPase	NA	K03650	NA	              Translation	               03010 Ribosome	COG0486	J
LFTS_00824	116.393483122229	-0.126654452879808	0.222379096313699	-0.569542978541216	0.568987712636503	0.732362056573203	189	hypothetical protein	NA	K06199	NA	              Replication and repair	               03440 Homologous recombination	COG0239	DP
LFTS_01039	54.4720274226202	0.161371740742787	0.283459435892759	0.569293945832301	0.56915667469808	0.732362056573203	612	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00022	443.793341853068	-0.103504494658253	0.182084476782644	-0.568442167542965	0.569734764638674	0.732726655401833	1026	NADPH:quinone reductase	NA	K00344	NA	              Cell growth and death	               04112 Cell cycle - Caulobacter	COG0604	CR
LFTS_01609	353.880130715903	-0.0903714651124865	0.159669546530515	-0.565990616721737	0.571400159205302	0.734488519019845	483	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01465	40.4304470867614	-0.181429436799425	0.321263108873739	-0.564737848162732	0.572252086742984	0.735040480509906	2553	Type IV secretory pathway%2C VirB4 component	NA	K12063	NA	              Membrane transport	               03070 Bacterial secretion system	NA	
LFTS_01095	5.80409864159302	0.242538035796876	0.429658918553538	0.564489704096888	0.572420905175856	0.735040480509906	339	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00303	197.280214308269	-0.117183064962148	0.207873916558587	-0.56372183149357	0.572943457337768	0.73533166491569	273	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01617	1010.17703507119	-0.0711388703652999	0.126728054754183	-0.56135060625123	0.57455854912602	0.737024021221509	1425	Outer membrane protein TolC	NA	K12340	 Drug resistance; Signal transduction; Membrane transport; Infectious diseases; Environmental adaptation	              Membrane transport	               03070 Bacterial secretion system	COG1538	M
LFTS_01234	280.503730464923	0.11841273774172	0.212011189982674	0.558521169337322	0.576488553058859	0.738931476173116	420	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01300	186.74790366965	0.116005214193255	0.207783191105585	0.558299319478191	0.576640009563896	0.738931476173116	1374	3-deoxy-D-manno-octulosonic-acid transferase	Lipopolysaccharide synthesis	K02527	 Glycan biosynthesis and metabolism	              Glycan biosynthesis and metabolism	               00540 Lipopolysaccharide biosynthesis	COG1519	M
LFTS_00685	1052.08503941542	0.0753123364015761	0.135084272850787	0.55752112967855	0.577171426643441	0.739231409910146	951	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD%2C containing LysM domain	NA	K08259	NA	              Folding, sorting and degradation	               03060 Protein export	NA	
LFTS_00314	34.8925853505906	-0.182567633181559	0.329235978042603	-0.554519084660714	0.579223648291697	0.741141566582394	1251	EAL domain%2C c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	c-di-GMP specific phosphodiestereases (EAL domain-containing proteins)	K14051	 Cellular community - prokaryotes	              Cellular community - prokaryotes	               02024 Quorum sensing	COG2199;COG2200;COG2202	T
LFTS_02035	18.4750992733491	0.214057340876271	0.386370903391397	0.554020344175425	0.579564922769217	0.741141566582394	180	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01783	993.618273993688	-0.0720419006202126	0.130123531676059	-0.553642371155126	0.579823622196422	0.741141566582394	939	Nucleoside-diphosphate-sugar epimerase	Lipopolysaccharide synthesis	K01784	 Carbohydrate metabolism	              Carbohydrate metabolism	               00052 Galactose metabolism	COG1087	M
LFTS_01458	133.1818494228	-0.125389298215261	0.227005894279798	-0.552361420451541	0.580700757157407	0.741141566582394	273	MtN3 and saliva related transmembrane protein	NA	K15383	NA	              Cell growth and death	               04112 Cell cycle - Caulobacter	NA	
LFTS_02126	595.761782861444	-0.0777322785336453	0.140734051316678	-0.552334547370722	0.580719165235079	0.741141566582394	1032	DNA polymerase-3 subunit delta'	NA	K02341	 Replication and repair; Nucleotide metabolism	              Nucleotide metabolism	               00230 Purine metabolism	COG0470	L
LFTS_01507	205.877927179197	-0.109919921145451	0.199039862059646	-0.55225079040957	0.580776540560293	0.741141566582394	384	general secretion pathway protein I	NA	K02458	 Cellular community - prokaryotes; Membrane transport	              Membrane transport	               03070 Bacterial secretion system	COG2165	NUW
LFTS_00396	1326.98939344141	0.0754108487436655	0.136631033634063	0.551930602718247	0.580995900498693	0.741141566582394	423	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01694	830.316611635318	0.0853376387827381	0.15463784602185	0.551854807720743	0.581047833173405	0.741141566582394	882	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase	NA	K00919	 Metabolism of terpenoids and polyketides	              Metabolism of terpenoids and polyketides	               00900 Terpenoid backbone biosynthesis	COG1947	I
LFTS_00954	615.492644585492	-0.0829567228324479	0.151112571081021	-0.548973008923061	0.58302397298687	0.743280818895056	1092	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase	NA	K00768	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00860 Porphyrin and chlorophyll metabolism	COG2038	H
LFTS_02051	178.968618222022	-0.106780948777901	0.194817031332621	-0.548108900168942	0.583617129720226	0.743655655809576	435	HD domain-containing protein	NA	K07814	NA	              Translation	               00970 Aminoacyl-tRNA biosynthesis	COG3437	T
LFTS_00693	12006.7700422066	0.0794127824719591	0.145503593061121	0.54577884161665	0.58521796907249	0.74508581142923	2712	formate dehydrogenase major subunit	NA	K00336	 Energy metabolism	              Energy metabolism	               00190 Oxidative phosphorylation	COG1034	C
LFTS_00420	3868.39430325123	-0.110977738012213	0.20340386575589	-0.545602895007904	0.585338933918458	0.74508581142923	414	nitrogen fixation protein NifU	Nitrogenase genes	K04488	NA	              Metabolism of cofactors and vitamins	               00730 Thiamine metabolism	COG0822	O
LFTS_01105	44.5718480212511	0.174320497204353	0.320853480774502	0.543302496776921	0.586921545488652	0.746717994925685	708	Methyltransferase domain-containing protein	NA	K00568	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00130 Ubiquinone and other terpenoid-quinone biosynthesis	COG2227	H
LFTS_02416	726.794290163633	-0.0800796090413205	0.147668479133321	-0.542293179365797	0.587616553534109	0.747181365489298	507	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00613	360.639678525736	0.101579987658694	0.187707282169447	0.54116167729175	0.588396149352976	0.747181365489298	309	hypothetical protein	NA	K09131	NA	              Overview	               01230 Biosynthesis of amino acids	COG1872	S
LFTS_02168	1712.21475669871	0.0684648863648883	0.126741097799287	0.540194834617199	0.589062674533686	0.747181365489298	1065	site-2 protease. Metallo peptidase. MEROPS family M50B	NA	K11749	 Cellular community - prokaryotes; Cell growth and death	              Cell growth and death	               04112 Cell cycle - Caulobacter	COG0750	OK
LFTS_01757	1506.99329374531	0.070783783902997	0.131059993740366	0.540086886034971	0.589137114099257	0.747181365489298	750	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	NA	K01420	NA	              Amino acid metabolism	               00260 Glycine, serine and threonine metabolism	COG0664	T
LFTS_00989	428.446713495155	-0.10124858380686	0.187577275349214	-0.539769988759909	0.589355666313673	0.747181365489298	225	T4 immunity holin family protein	NA	K05566	NA	              Membrane transport	               03070 Bacterial secretion system	COG2111	P
LFTS_00750	582.002380157285	-0.0911583391713903	0.168890210214666	-0.539749101238754	0.589370072970376	0.747181365489298	636	hypothetical protein	NA	K15539	NA	              Energy metabolism	               00190 Oxidative phosphorylation	COG1426	D
LFTS_01066	310.068402523108	-0.0932769294596584	0.172824435217907	-0.539720724919771	0.589389645102379	0.747181365489298	1011	helix-turn-helix protein	NA	K07729	NA	              Translation	               03010 Ribosome	COG1476	K
LFTS_01377	238.50217495533	0.119065429156597	0.221570054943158	0.537371483647202	0.591011036947715	0.748854963227329	1125	acetate kinase	NA	K00925	 Carbohydrate metabolism; Overview; Metabolism of other amino acids; Energy metabolism	              Overview	               01200 Carbon metabolism	COG0282	C
LFTS_01306	292.768104876653	-0.0961746883890925	0.179893885780288	-0.534618994814279	0.592913346128769	0.750388660991452	753	(heptosyl)LPS beta-1%2C4-glucosyltransferase	Lipopolysaccharide synthesis	K12984	NA	              Glycan biosynthesis and metabolism	               00540 Lipopolysaccharide biosynthesis	COG0463	M
LFTS_01903	68.3919328158725	0.145304917397714	0.271824416643449	0.534554324412695	0.592958075073451	0.750388660991452	126	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01621	1486.69933575009	-0.0936291055797913	0.17523364026147	-0.534310109862953	0.593126998732181	0.750388660991452	1473	Outer membrane protein TolC	NA	K12340	 Drug resistance; Signal transduction; Membrane transport; Infectious diseases; Environmental adaptation	              Membrane transport	               03070 Bacterial secretion system	COG1538	M
LFTS_01797	173.069796907465	0.110820292490573	0.207660587953118	0.533660689218467	0.593576311431606	0.750575132359599	291	Transposase	NA	K07483	NA	              Signal transduction	               02020 Two-component system	COG2963	X
LFTS_02444	1317.55875723568	-0.0817736895218515	0.153927584526901	-0.531247792740882	0.59524707808996	0.752305153091836	546	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00948	2024.46955722075	-0.0846160014507782	0.160084788849886	-0.528569903853413	0.597103842659357	0.7542683703512	1923	molecular chaperone DnaK	Chaperones	K04043	 Aging; Folding, sorting and degradation; Infectious diseases	              Folding, sorting and degradation	               03018 RNA degradation	COG0443	O
LFTS_01596	535.027101827216	0.0819192435549197	0.155800356376771	0.525796252717259	0.599029778438857	0.756316926967495	447	Response regulator receiver domain-containing protein	NA	K02485	NA	              Cellular community - prokaryotes	               02024 Quorum sensing	COG2197	TK
LFTS_01109	359.914208442186	-0.096509084526285	0.183946126358313	-0.524659510025738	0.599819909323176	0.756342576838732	1104	hypothetical protein	NA	K06871	NA	              Signal transduction	               02020 Two-component system	COG0641	O
LFTS_01062	99.3919531177662	-0.127078602414477	0.242249576309849	-0.524577191631238	0.59987714577862	0.756342576838732	1014	dTMP kinase	NA	K00943	 Nucleotide metabolism	              Nucleotide metabolism	               00240 Pyrimidine metabolism	COG0125	F
LFTS_00251	456.063916238217	-0.0793144311529419	0.151232392844326	-0.524453985427484	0.599962816382132	0.756342576838732	483	NitT/TauT family transport system ATP-binding protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00716	1341.21573393678	0.0805637491420456	0.154034335041415	0.523024617338625	0.600957122263803	0.757084164878226	642	Tetratricopeptide repeat-containing protein	NA	K12600	 Folding, sorting and degradation	              Folding, sorting and degradation	               03018 RNA degradation	COG0457	R
LFTS_00561	172.492939991016	-0.1079337541615	0.206479749371062	-0.522732880538002	0.601160153447151	0.757084164878226	1098	Mechanosensitive ion channel	NA	K16052	NA	              Metabolism of cofactors and vitamins	               00860 Porphyrin and chlorophyll metabolism	COG0668	M
LFTS_00162	896.305482066172	0.0685968290199287	0.131709456750837	0.520819314817291	0.602492646627853	0.757654738053664	1209	hypothetical protein	NA	K14110	NA	              Overview	               01210 2-Oxocarboxylic acid metabolism	COG1863	P
LFTS_01096	17.3855451091171	0.212512706757885	0.408382397578669	0.520376754771728	0.602801008386845	0.757654738053664	609	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00678	2061.94047736063	-0.0784585259447301	0.150920365942013	-0.519867053429196	0.603156240065734	0.757654738053664	1512	Exodeoxyribonuclease VII large subunit	NA	K03601	 Replication and repair	              Replication and repair	               03430 Mismatch repair	COG1570	L
LFTS_00982	69.6368917883137	-0.140927790218576	0.271272069420167	-0.519507188925876	0.603407101033503	0.757654738053664	1449	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01780	1158.4517875873	-0.0870581947832123	0.167667573264624	-0.519230958545642	0.603599692608752	0.757654738053664	1047	pyruvate dehydrogenase E1 component beta subunit	NA	K00162	 Carbohydrate metabolism; Overview; Signal transduction; Cancers; Endocrine system	              Overview	               01200 Carbon metabolism	COG0022	C
LFTS_01249	43.8828264904637	-0.166070598879443	0.319930437250346	-0.519083461726065	0.60370254071011	0.757654738053664	2022	Tetratricopeptide repeat-containing protein	putative pel operon	K15201	NA	              Translation	               00970 Aminoacyl-tRNA biosynthesis	NA	
LFTS_01145	701.756159568618	0.0801135682956759	0.154463290811694	0.518657655645458	0.603999495334199	0.757654738053664	6510	hypothetical protein	NA	K03580	NA	              Metabolism of cofactors and vitamins	               00860 Porphyrin and chlorophyll metabolism	COG0553	KL
LFTS_00865	2488.45877694269	0.0667358937619144	0.128688862525915	0.518583290364194	0.604051363967161	0.757654738053664	516	putative holliday junction resolvase	NA	K07447	NA	              Translation	               00970 Aminoacyl-tRNA biosynthesis	COG0816	K
LFTS_01434	535.117763777814	-0.0918362167783584	0.17745979973676	-0.51750434134709	0.604804139155304	0.758216384236049	231	hypothetical protein	NA	K07143	NA	              Cell growth and death	               04112 Cell cycle - Caulobacter	COG1645	R
LFTS_02398	768.049852890775	0.082960193278025	0.160505738173238	0.516867460454804	0.605248683877712	0.758391244012093	456	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00245	166.497235347527	-0.119140990359511	0.230882691995923	-0.516023913830729	0.605837707169046	0.758746871547732	1089	hypothetical protein	NA	K07286	NA	              Overview	               01200 Carbon metabolism	COG3056	S
LFTS_01093	3.99833370711272	-0.216475007203086	0.420875894944964	-0.514344037762945	0.607011477787906	0.759834105629775	537	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01538	388.610430760467	-0.0797334886443324	0.155357525729139	-0.513225788516646	0.607793388620191	0.760429976904779	699	1-acyl-sn-glycerol-3-phosphate acyltransferase	NA	K00655	 Lipid metabolism	              Lipid metabolism	               00561 Glycerolipid metabolism	COG0204	I
LFTS_00985	655.424784595925	0.0729381242117939	0.142428314847284	0.512104101561551	0.608578154143524	0.760932435463917	1719	AlwI restriction endonuclease	NA	NA	NA	NA	NA	NA	NA
LFTS_01373	514.333374335445	-0.0735387097507759	0.143692908239028	-0.511776890397727	0.60880716578348	0.760932435463917	720	phosphoribosylaminoimidazole-succinocarboxamide synthase	NA	K01923	 Nucleotide metabolism	              Nucleotide metabolism	               00230 Purine metabolism	COG0152	F
LFTS_00419	3418.01390657144	-0.103609972653974	0.20290576704449	-0.510630989760166	0.609609471768517	0.761552335083685	330	iron-sulfur cluster assembly protein	NA	K13628	NA	              Replication and repair	               03030 DNA replication	COG0316	O
LFTS_00372	8209.08862188551	-0.0731191873912239	0.143357891407699	-0.510046476501796	0.610018901498692	0.761681059329858	1044	chlorite dismutase	NA	K09162	NA	              Overview	               01210 2-Oxocarboxylic acid metabolism	COG3253	P
LFTS_00297	319.951905411485	0.104454030645795	0.205131013862472	0.509206427048738	0.610607538577191	0.762033303666113	693	haloacid dehalogenase superfamily%2C subfamily IA%2C variant 3 with third motif having DD or ED	NA	K01838	 Carbohydrate metabolism	              Carbohydrate metabolism	               00500 Starch and sucrose metabolism	COG0637	GR
LFTS_00770	1369.16484359353	0.0746282014059373	0.146831229243388	0.508258371127801	0.611272160127581	0.762479974950912	1476	mannose-1-phosphate guanylyltransferase / mannose-6-phosphate isomerase	Extracellular polysaccharide production and export	K16011	 Carbohydrate metabolism; Cellular community - prokaryotes	              Carbohydrate metabolism	               00051 Fructose and mannose metabolism	COG0662;COG0836	GM
LFTS_01170	6.70720482865054	0.220003619068735	0.433718807890932	0.507249432272857	0.611979814657411	0.762580763827429	258	4Fe-4S dicluster domain-containing protein	NA	K03616	NA	              Metabolism of terpenoids and polyketides	               00523 Polyketide sugar unit biosynthesis	COG2878	C
LFTS_02520	133.518351111616	-0.124174083599283	0.244884045330741	-0.507072983997684	0.612103610054059	0.762580763827429	615	2'-5' RNA ligase	NA	K01975	NA	              Metabolism of cofactors and vitamins	               00860 Porphyrin and chlorophyll metabolism	COG1514	J
LFTS_00813	533.382075969091	0.0973327656300053	0.192065337633075	0.506769034066686	0.612316886070142	0.762580763827429	402	holo-[acyl-carrier protein] synthase	NA	K00997	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00770 Pantothenate and CoA biosynthesis	COG0736	I
LFTS_01120	69.4537676854085	0.141745697038909	0.279911783409186	0.506394176452729	0.612579961932171	0.762580763827429	1311	hypothetical protein	NA	K00795	 Metabolism of terpenoids and polyketides	              Metabolism of terpenoids and polyketides	               00900 Terpenoid backbone biosynthesis	COG0142	H
LFTS_02053	1096.32207834242	-0.0645272160456077	0.127931484307278	-0.504388864047102	0.613988141931685	0.763951211632718	294	hypothetical protein	NA	K13582	 Cell growth and death	              Cell growth and death	               04112 Cell cycle - Caulobacter	COG0790;COG3409	TM
LFTS_01583	1179.23252652713	0.0747867298356081	0.148866496639409	0.50237448669703	0.615404122264348	0.764747416090226	2178	Glycogen debranching enzyme (alpha-1%2C6-glucosidase)	NA	K05989	NA	              Metabolism of cofactors and vitamins	               00770 Pantothenate and CoA biosynthesis	NA	
LFTS_02052	30.1712107917218	0.18653314842669	0.371486073426378	0.50212689457296	0.615578262947874	0.764747416090226	123	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00974	87.1836737223722	0.124735151832219	0.248461764966527	0.502029565188929	0.61564672422653	0.764747416090226	675	type IV secretion system protein VirB5	NA	K03203	 Membrane transport	              Membrane transport	               03070 Bacterial secretion system	COG3736	U
LFTS_01097	15.6721337976473	-0.208916474664878	0.416445158471468	-0.501666234833155	0.615902319563091	0.764747416090226	723	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01467	17.3713461294172	-0.195495130437673	0.390188590269783	-0.501027286068268	0.616351919706942	0.764747416090226	1233	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00017	136.186534197825	0.114283811532097	0.228177832823963	0.500854136958455	0.616473781916659	0.764747416090226	177	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00096	437.851954555408	-0.0929209883929416	0.186096568426833	-0.499315969007109	0.617556806979254	0.765652835691656	1044	peptide/nickel transport system ATP-binding protein	NA	K02032	 Cellular community - prokaryotes	              Cellular community - prokaryotes	               02024 Quorum sensing	COG1123;COG1124	OEP
LFTS_01562	1069.28842152884	0.0964266798477837	0.193261962195193	0.498942879149666	0.617819625260443	0.765652835691656	1674	dihydroxy-acid dehydratase	NA	K01687	 Metabolism of cofactors and vitamins; Amino acid metabolism; Overview	              Overview	               01210 2-Oxocarboxylic acid metabolism	COG0129	EG
LFTS_00996	444.590781129664	0.0809638885894746	0.162648326901139	0.497784945790964	0.618635627760372	0.766282097963271	525	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01324	841.683680728743	0.0683689451969713	0.137694359072606	0.496526841458483	0.61952275460435	0.766889813264049	1056	hypothetical protein	NA	K06865	NA	              Metabolism of terpenoids and polyketides	               00900 Terpenoid backbone biosynthesis	COG1855	R
LFTS_02020	27.1689545315876	-0.187431964544783	0.377723819774457	-0.49621430985396	0.619743215948301	0.766889813264049	360	hypothetical protein	NA	K07733	NA	              Membrane transport	               02010 ABC transporters	COG3311	KX
LFTS_01261	141.512421802142	-0.125264797393265	0.255591671684578	-0.490097335987742	0.624065023124289	0.771853555963672	558	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01022	32.2005701525961	0.162842602819795	0.333186776302071	0.488742694494453	0.625023873202471	0.77241066375755	279	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01366	857.462701153769	-0.0689588033263098	0.141140373130922	-0.488583116202645	0.625136868656553	0.77241066375755	720	Thiol-disulfide isomerase or thioredoxin	NA	K02199	NA	              Metabolism of cofactors and vitamins	               00760 Nicotinate and nicotinamide metabolism	COG0526	O
LFTS_01527	977.69387616047	-0.074965680268374	0.154002803886983	-0.486781268757862	0.626413345836627	0.773401596203753	720	sugar fermentation stimulation protein A	NA	K06206	NA	              Nucleotide metabolism	               00230 Purine metabolism	COG1489	GT
LFTS_00661	721.765486004355	0.0659393733561169	0.135517987503156	0.486572849634306	0.626561067881882	0.773401596203753	1158	putative metallophosphoesterase	NA	K07098	NA	              Overview	               01210 2-Oxocarboxylic acid metabolism	COG1408	R
LFTS_01956	1336.41613500749	-0.0616896083288486	0.127249788818038	-0.484791439748965	0.627824295559809	0.774408351280574	1506	anthranilate synthase component 1	NA	K01657	 Cellular community - prokaryotes; Overview; Amino acid metabolism	              Overview	               01230 Biosynthesis of amino acids	COG0147	EH
LFTS_01965	1748.21173570946	-0.0670993509036315	0.138479314703095	-0.484544215484421	0.627999692752066	0.774408351280574	1089	iron(II)-dependent oxidoreductase	NA	K13444	 Transport and catabolism	              Transport and catabolism	               04142 Lysosome	NA	
LFTS_01968	1079.86347615451	-0.0741979859408782	0.154058267349347	-0.481622876963979	0.630073871781839	0.776580885101463	207	hypothetical protein	NA	K00407	 Energy metabolism; Signal transduction	              Energy metabolism	               00190 Oxidative phosphorylation	NA	
LFTS_02456	8196.37468879067	0.0688087314596095	0.143246801512037	0.480350909991016	0.630977894217778	0.77700811220857	699	pyruvate ferredoxin oxidoreductase gamma subunit	Reductive TCA cycle carbon dioxide fixation	K00172	 Carbohydrate metabolism; Overview; Energy metabolism; Xenobiotics biodegradation and metabolism	              Overview	               01200 Carbon metabolism	COG1014	C
LFTS_02192	512.67263911377	-0.0906301199026412	0.188738769908545	-0.480188145480428	0.631093615397276	0.77700811220857	960	muramoyltetrapeptide carboxypeptidase	NA	K01297	NA	              Carbohydrate metabolism	               00630 Glyoxylate and dicarboxylate metabolism	COG1619	M
LFTS_01920	599.411125155675	-0.0735198349555223	0.153225025678497	-0.47981610464719	0.631358160362555	0.77700811220857	927	aspartate carbamoyltransferase	NA	K00609	 Nucleotide metabolism; Amino acid metabolism	              Nucleotide metabolism	               00240 Pyrimidine metabolism	COG0540	F
LFTS_01402	621.116339886336	-0.0897211484597953	0.187235726496009	-0.479188187739949	0.631804756783337	0.777172996221364	399	hypothetical protein	NA	K12193	 Transport and catabolism	              Transport and catabolism	               04144 Endocytosis	NA	
LFTS_00192	201.773360239086	-0.0957275793356038	0.201264348391013	-0.475631079726182	0.634337229338827	0.779648907088304	342	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00889	348.235639446877	0.101269346663102	0.213121300733636	0.475172337605384	0.634664142139955	0.779648907088304	372	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_02505	545.290197773379	-0.0873204732038066	0.183817062860247	-0.475040085207948	0.634758402231186	0.779648907088304	822	Transposase DDE domain group 1	NA	NA	NA	NA	NA	NA	NA
LFTS_02315	164.678309704719	0.0977240445425572	0.205963722826699	0.474472121601646	0.635163273556496	0.779760937314296	1368	NADH-quinone oxidoreductase subunit M	NADH dehydrogenase	K05568	NA	              Energy metabolism	               00190 Oxidative phosphorylation	COG0651	CP
LFTS_02238	197.360225135125	0.0927110230702994	0.195888681898639	0.47328422536567	0.63601041484628	0.780357178866591	159	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00615	65.3619013374414	0.136687149601092	0.289145605744598	0.47272774299682	0.636407430930712	0.780357178866591	594	Transposase	NA	K07488	NA	              Replication and repair	               03410 Base excision repair	COG3676	X
LFTS_01777	1230.94788379796	0.0878910649120809	0.186136874328304	0.472185133812124	0.636794649929767	0.780357178866591	999	D-glycero-alpha-D-manno-heptose-7-phosphate kinase	NA	K07031	 Glycan biosynthesis and metabolism	              Glycan biosynthesis and metabolism	               00540 Lipopolysaccharide biosynthesis	COG2605	R
LFTS_02483	184.736629417574	0.098991885263824	0.209714728503183	0.472031153798153	0.636904551858533	0.780357178866591	732	Peptidase family M50	NA	K11749	 Cellular community - prokaryotes; Cell growth and death	              Cell growth and death	               04112 Cell cycle - Caulobacter	COG0750	OK
LFTS_00262	162.818233947815	0.109920929749253	0.234569365711526	0.468607353802689	0.639350319923873	0.782872575016218	789	16S rRNA (cytidine1402-2'-O)-methyltransferase	NA	K07056	NA	              Metabolism of other amino acids	               00410 beta-Alanine metabolism	COG0313	J
LFTS_01459	274.157108274263	0.0907063500996295	0.193702833533478	0.468275803946629	0.639587369210755	0.782872575016218	1143	putative secreted hydrolase	NA	NA	NA	NA	NA	NA	NA
LFTS_00683	1048.04857405029	-0.059843380863087	0.128110408032558	-0.467123489668991	0.640411529254437	0.783487783363174	942	UDP-glucose 4-epimerase	Extracellular polysaccharide production and export	K01784	 Carbohydrate metabolism	              Carbohydrate metabolism	               00052 Galactose metabolism	COG1087	M
LFTS_01098	12.382887003931	0.19944481316108	0.427358600471131	0.466691937265815	0.640720299105926	0.783487783363174	411	hypothetical protein	NA	K06930	NA	              Amino acid metabolism	               00310 Lysine degradation	COG3413	R
LFTS_01966	1028.50136256105	0.0608570025849459	0.13103089525015	0.46444773554179	0.642326996437361	0.785066328978997	558	Cytochrome C and Quinol oxidase polypeptide I	NA	K00404	 Energy metabolism; Signal transduction	              Energy metabolism	               00190 Oxidative phosphorylation	COG3278	C
LFTS_02448	9283.53882364938	0.0635703598334092	0.13781539511594	0.461271832366257	0.64460359116031	0.787461684336378	582	CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit	NA	NA	NA	NA	NA	NA	NA
LFTS_00486	1022.77700310159	-0.100087482040404	0.219055838953402	-0.456903968041204	0.647740071771165	0.79034479476524	627	3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit	NA	K01704	 Amino acid metabolism; Overview; Carbohydrate metabolism	              Overview	               01210 2-Oxocarboxylic acid metabolism	COG0066	E
LFTS_00477	412.286932984806	0.098137715032946	0.214984582000077	0.456487223967117	0.648039655970217	0.79034479476524	558	peptide-methionine (S)-S-oxide reductase	NA	K07304	NA	              Translation	               00970 Aminoacyl-tRNA biosynthesis	COG0225	O
LFTS_02163	1735.17402549	-0.0554847954823008	0.121584544659574	-0.456347438218018	0.648140156313523	0.79034479476524	996	phosphate:acyl-[acyl carrier protein] acyltransferase	NA	K03621	 Lipid metabolism	              Lipid metabolism	               00561 Glycerolipid metabolism	COG0416	I
LFTS_00529	118.690241810909	-0.109348408349845	0.239828987607739	-0.455943251233222	0.648430786597833	0.79034479476524	1095	Glycosyl transferase family 2	Extracellular polysaccharide production and export	K07011	NA	              Cell motility	               02040 Flagellar assembly	COG1216	G
LFTS_01766	250.997003018597	-0.0949916505486507	0.208745003322071	-0.455060715403515	0.649065559297448	0.79034479476524	423	Toxin FitB	NA	K07062	NA	              Amino acid metabolism	               00260 Glycine, serine and threonine metabolism	COG1487	R
LFTS_02479	1539.56409962207	-0.0639779022123756	0.140661046204364	-0.454837383474478	0.649226233457355	0.79034479476524	1023	23S rRNA/1915/1917 synthase	NA	K06180	NA	              Folding, sorting and degradation	               04120 Ubiquitin mediated proteolysis	COG0564	J
LFTS_02449	4082.81457106619	-0.0708947454876095	0.156091579008817	-0.454186868617717	0.64969433354413	0.79034479476524	231	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00553	34.9374154609191	-0.151814698826029	0.334527030592387	-0.453818929242259	0.649959158088703	0.79034479476524	387	PIN domain nuclease%2C a component of toxin-antitoxin system (PIN domain)	NA	K07064	NA	              Signal transduction	               02020 Two-component system	COG1848	R
LFTS_01057	46.2694894229124	0.137584724029487	0.303322630443896	0.453592017938586	0.650122499658039	0.79034479476524	477	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01114	38.9716329228234	0.150561385879094	0.331951974692499	0.453563760295644	0.650142842033353	0.79034479476524	558	hypothetical protein	NA	K07175	NA	              Signal transduction	               02020 Two-component system	COG1875	R
LFTS_01019	2624.84446531508	0.0664522375883486	0.146800651523629	0.452669909149911	0.650786450419827	0.790740525778929	333	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01173	7.934005731746	0.195888116837753	0.433256790296893	0.452129363520234	0.651175791190364	0.790827072251707	792	Leucine rich repeat variant	NA	NA	NA	NA	NA	NA	NA
LFTS_00746	1495.0706576189	0.109607168537786	0.243196673180081	0.450693535830668	0.652210441909779	0.791696854779155	1647	glucose-6-phosphate isomerase	NA	K01810	 Carbohydrate metabolism; Overview	              Overview	               01200 Carbon metabolism	COG0166	G
LFTS_01578	1034.68533879033	-0.072985793109076	0.162824461450374	-0.448248331110377	0.653973985587717	0.793450135759426	1041	biotin synthase	NA	K01012	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00780 Biotin metabolism	COG0502	H
LFTS_01747	378.926749840755	-0.106939848080455	0.239159920930139	-0.447147865179692	0.654768301102361	0.794026339775839	657	Polyisoprenoid-binding protein YceI	NA	NA	NA	NA	NA	NA	NA
LFTS_00163	718.271517288217	-0.0719602113157487	0.161198493456341	-0.446407468040254	0.65530293927461	0.794275156723546	846	hypothetical protein	NA	K09778	NA	              Overview	               01210 2-Oxocarboxylic acid metabolism	COG2121	S
LFTS_01350	928.063454123438	-0.06628002034927	0.148856151138637	-0.445262220219172	0.656130266736004	0.794275156723546	627	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01731	1220.34943434893	0.111160965795609	0.249883864913145	0.444850514194851	0.656427786488629	0.794275156723546	945	methyl-accepting chemotaxis protein	Chemotaxis	K03406	 Signal transduction; Cell motility	              Signal transduction	               02020 Two-component system	COG0840	NT
LFTS_00835	794.171201093781	-0.0710579179487466	0.15991854633223	-0.444338193276996	0.656798091784826	0.794275156723546	465	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00756	417.099343618637	0.0674317915022952	0.151876943588087	0.443989653131157	0.657050064615676	0.794275156723546	666	hypothetical protein	NA	K14770	NA	              Energy metabolism	               00190 Oxidative phosphorylation	NA	
LFTS_02043	111.715098976201	-0.116964517325484	0.263661582330097	-0.443616078959305	0.657320178785693	0.794275156723546	1065	cobalt-zinc-cadmium efflux system protein	Cadmium/cobalt/zinc resistance	K16264	NA	              Metabolism of cofactors and vitamins	               00860 Porphyrin and chlorophyll metabolism	COG1230	P
LFTS_01988	2005.13864308193	-0.0539033242212681	0.12152623065957	-0.443553000275855	0.657365792476849	0.794275156723546	1152	lysine 2%2C3-aminomutase	NA	K01843	 Amino acid metabolism	              Amino acid metabolism	               00310 Lysine degradation	COG1509	E
LFTS_01106	36.5186413999897	0.144412246766519	0.325746812401288	0.443326661286302	0.657529474069613	0.794275156723546	405	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_02029	56.1575697461256	0.136451068391451	0.308622199048674	0.442129791091051	0.658395287733063	0.794546823696247	441	hypothetical protein	NA	K01507	 Energy metabolism	              Energy metabolism	               00190 Oxidative phosphorylation	COG0221	CP
LFTS_00584	2844.07259665862	0.0551099230804942	0.124703357729773	0.441928141180571	0.658541206039467	0.794546823696247	687	2Fe-2S iron-sulfur cluster binding domain-containing protein	NA	K00192	 Energy metabolism; Overview	              Overview	               01200 Carbon metabolism	COG1152	C
LFTS_01018	185.109178124627	0.0876115759393673	0.198355134975857	0.441690485855236	0.658713195349141	0.794546823696247	552	Transglycosylase SLT domain-containing protein	NA	K08309	NA	              Amino acid metabolism	               00260 Glycine, serine and threonine metabolism	COG0741	M
LFTS_01151	207.472784526998	-0.0825617799220301	0.187200146694806	-0.44103480354976	0.659187801128885	0.794733692340644	480	leader peptidase (prepilin peptidase) / N-methyltransferase	NA	K02654	NA	              Signal transduction	               02020 Two-component system	COG1989	NU
LFTS_01079	53.0034987262653	0.13158038001296	0.299855182461818	0.438813092815943	0.660796972614514	0.796095799048776	1140	hypothetical protein	NA	K06871	NA	              Energy metabolism	               00190 Oxidative phosphorylation	COG0641	O
LFTS_01522	388.812801792288	-0.0772892339832623	0.176326516794185	-0.438330180783174	0.661146950724454	0.796095799048776	1212	tyrosyl-tRNA synthetase	NA	K01866	 Translation	              Translation	               00970 Aminoacyl-tRNA biosynthesis	COG0162	J
LFTS_02102	1004.58684352917	0.0726770866742928	0.166037127394201	0.43771587605069	0.661592259384561	0.796095799048776	366	L-aspartate 1-decarboxylase	Proton consuming reactions	K01579	 Metabolism of cofactors and vitamins; Metabolism of other amino acids	              Metabolism of other amino acids	               00410 beta-Alanine metabolism	COG0853	H
LFTS_01412	185.64529181726	0.0957370315645186	0.218723892772843	0.437707240625728	0.661598520046167	0.796095799048776	981	hypothetical protein	NA	K08372	 Signal transduction	              Signal transduction	               02020 Two-component system	COG0265	O
LFTS_02225	390.206711360867	0.099579310474304	0.227741622775466	0.437246864498197	0.661932325843371	0.796112124841132	567	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01925	614.288209832691	-0.0722273755978194	0.16566010335531	-0.435997407552652	0.662838610495445	0.796816627510482	459	CBS domain-containing protein	NA	K04767	NA	              Metabolism of cofactors and vitamins	               00860 Porphyrin and chlorophyll metabolism	COG0517	T
LFTS_00878	855.483999745691	0.0728597380451954	0.167678665377174	0.434520026034952	0.663910855702466	0.797684563840611	639	lipopolysaccharide export system protein LptA	NA	K09774	NA	              Translation	               03010 Ribosome	COG1934	M
LFTS_00859	983.942756762325	0.0588088675365024	0.135467297721806	0.434118554998208	0.664202352031402	0.797684563840611	615	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_02474	349.095928427097	0.0695110758535556	0.160375167763014	0.433427922933007	0.664703918548357	0.797901468619611	726	Bacterial regulatory helix-turn-helix protein%2C lysR family	NA	K03091	NA	              Folding, sorting and degradation	               03060 Protein export	NA	
LFTS_01599	2334.58207072319	0.0890022371898777	0.205557460816944	0.432979843378865	0.665029413395596	0.797906912018075	324	hypothetical protein	NA	K07164	NA	              Metabolism of cofactors and vitamins	               00730 Thiamine metabolism	COG1579	R
LFTS_01728	79.1473051848945	-0.110038315641911	0.254410658183713	-0.432522428217024	0.665361754975927	0.797920560960036	564	putative phage-associated protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01122	78.9570442386397	0.124347042932989	0.287972020674903	0.431802515541488	0.665884951077722	0.797951121312102	1161	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00671	779.788170324747	-0.060965396848454	0.141253060341287	-0.431604077824247	0.666029194176433	0.797951121312102	1104	protein TonB	NA	K03832	NA	              Energy metabolism	               00190 Oxidative phosphorylation	COG0810	M
LFTS_00600	120.423557364271	-0.0960725106838607	0.223387840247075	-0.430070457629211	0.667144389171359	0.798724660440679	489	cell division protein FtsW	NA	K03588	 Cell growth and death	              Cell growth and death	               04112 Cell cycle - Caulobacter	COG0772	D
LFTS_01250	165.021673276373	0.0913021888351429	0.212596791862688	0.429461743214419	0.667587229113672	0.798724660440679	2193	putative membrane protein-like protein	putative pel operon	NA	NA	NA	NA	NA	NA
LFTS_02013	31.1791062301646	-0.145688498648427	0.339357525262631	-0.429306815977274	0.667699957220571	0.798724660440679	831	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01241	49.7170034996288	0.126456595288609	0.294805347738414	0.428949461937225	0.667960003642869	0.798724660440679	756	LuxR family transcriptional regulator	Quorum sensing	K07782	 Cellular community - prokaryotes; Signal transduction	              Signal transduction	               02020 Two-component system	COG2771;COG2197	KTK
LFTS_00019	149.213234717081	-0.0870133100401536	0.203554047611145	-0.427470301186924	0.669036812158231	0.799297817357793	1671	2-isopropylmalate synthase	NA	K01649	 Amino acid metabolism; Overview; Carbohydrate metabolism	              Overview	               01210 2-Oxocarboxylic acid metabolism	COG0119	E
LFTS_01121	48.9171808211191	0.130866138684157	0.306331485995105	0.42720433473903	0.669230504342198	0.799297817357793	747	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01115	28.1668762424861	0.147739134776761	0.346482769597144	0.426396772770366	0.669818752597871	0.799297817357793	354	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01084	179.382112981213	0.0940812536140923	0.220930265224415	0.425841400762938	0.670223416993835	0.799297817357793	1104	hypothetical protein	NA	K06871	NA	              Metabolism of cofactors and vitamins	               00730 Thiamine metabolism	COG0641	O
LFTS_00890	205.755724562269	0.0806557906413326	0.189404781806465	0.425838196227524	0.670225752213599	0.799297817357793	783	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01178	6.02427849595666	-0.184566069277807	0.433617683085152	-0.425642395311546	0.670368442956958	0.799297817357793	300	NifU-like domain-containing protein	Nitrogenase genes	K13819	NA	              Energy metabolism	               00190 Oxidative phosphorylation	COG0694;COG0822	O
LFTS_01081	29.2519873819765	0.152240478302942	0.360516787702791	0.422284019762345	0.672817720867626	0.801833582970718	405	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01405	325.763600222205	-0.0725866560908397	0.172887702186583	-0.4198485790071	0.674596074086707	0.803567724091784	756	putative phosphoesterase	NA	K07096	NA	              Transport and catabolism	               04144 Endocytosis	COG2129	R
LFTS_00949	1219.77633584108	0.0596058592668068	0.14273370765304	0.417601842248068	0.676238249619353	0.805138069230705	1119	molecular chaperone DnaJ	NA	K03686	NA	              Folding, sorting and degradation	               03018 RNA degradation	COG0484	O
LFTS_00344	49.7700493820223	0.127225516865894	0.305750061019366	0.416109538757656	0.677329850296566	0.806051703129374	204	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00714	381.840405437023	-0.0734418759654345	0.176873573048672	-0.415222436566173	0.67797907552747	0.806438268785307	1182	diguanylate cyclase (GGDEF) domain-containing protein	Putative diguanylate cyclases (GGDEF domain-containing proteins)	K13069	NA	              Replication and repair	               03410 Base excision repair	COG2199	T
LFTS_02042	58.3233896370084	-0.133017407758198	0.320825195892679	-0.414610228439459	0.678427259209971	0.806442158182177	306	DNA-binding transcriptional regulator%2C ArsR family	NA	K03892	NA	              Metabolism of cofactors and vitamins	               00860 Porphyrin and chlorophyll metabolism	COG0640	K
LFTS_00505	1041.50726593349	0.115719655103683	0.279292240532788	0.414331794119779	0.678631132307769	0.806442158182177	1992	alpha-1%2C4-glucan:maltose-1-phosphate maltosyltransferase	NA	K16147	 Carbohydrate metabolism	              Carbohydrate metabolism	               00500 Starch and sucrose metabolism	COG0366	G
LFTS_01786	912.975409030947	0.0735072718426958	0.178693709360913	0.411359034996754	0.680809287318142	0.808643998219255	819	putative transposase	NA	K07497	NA	              Carbohydrate metabolism	               00500 Starch and sucrose metabolism	COG2801	X
LFTS_01653	1096.55825605865	0.0773634027033693	0.188712996721142	0.409952700913799	0.681840644756003	0.809482255426659	333	large subunit ribosomal protein L22	NA	K02890	 Translation	              Translation	               03010 Ribosome	COG0091	J
LFTS_00603	978.929110599316	0.0570703174841993	0.139431758379273	0.409306446017561	0.682314785611631	0.809658499775902	852	UDP-N-acetylmuramate dehydrogenase	NA	K00075	 Carbohydrate metabolism; Glycan biosynthesis and metabolism	              Carbohydrate metabolism	               00520 Amino sugar and nucleotide sugar metabolism	COG0812	M
LFTS_00914	60.9535441540914	-0.118997924336119	0.291604439340822	-0.408079947634257	0.683214981214418	0.810339906154123	648	hypothetical protein	NA	K02415	NA	              Replication and repair	               03440 Homologous recombination	COG1580	N
LFTS_01519	90.7990698670535	-0.105161558184614	0.260720755371778	-0.403349392090621	0.686691211023962	0.814074559182437	708	GMP synthase (glutamine-hydrolysing)	NA	K01951	 Xenobiotics biodegradation and metabolism; Nucleotide metabolism	              Nucleotide metabolism	               00230 Purine metabolism	COG0518;COG0519	F
LFTS_01792	94.0344007199842	-0.114533462658512	0.284540273535743	-0.402521095644214	0.687300566215729	0.814082312082519	447	hypothetical protein	NA	K02315	NA	              Signal transduction	               02020 Two-component system	COG1484	L
LFTS_00036	225.633442365644	-0.0729220237085836	0.181195119384527	-0.402450264423682	0.687352684256318	0.814082312082519	840	Methyltransferase domain-containing protein	NA	K02169	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00780 Biotin metabolism	COG0500	QR
LFTS_00013	419.188450085864	0.0617355952229306	0.153798661847055	0.401405281954426	0.688121761206843	0.814605094457244	291	addiction module antidote protein%2C HigA family	NA	K07729	NA	              Membrane transport	               02010 ABC transporters	COG1476	K
LFTS_00792	1132.84632286455	0.0620621688453042	0.155143304473801	0.400031242442593	0.689133505605706	0.815234105227945	996	phosphate starvation-inducible protein PhoH	NA	K06217	NA	              Cell growth and death	               04112 Cell cycle - Caulobacter	COG1702	T
LFTS_01717	726.79720054061	0.0695024332431967	0.173998704709029	0.399442245040977	0.689567371581636	0.815234105227945	1002	NADPH2:quinone reductase	NA	K00344	NA	              Metabolism of cofactors and vitamins	               00790 Folate biosynthesis	COG0604	CR
LFTS_01094	6.40517313939706	-0.173339131414351	0.434055474909398	-0.399347874717012	0.689636895934983	0.815234105227945	789	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00415	641.948743816676	-0.0690964849215974	0.173223390264934	-0.398886575397923	0.689976781325723	0.815248231167181	204	FeS assembly protein IscX	NA	NA	NA	NA	NA	NA	NA
LFTS_01541	111.730025669381	0.116877225979356	0.294523578521479	0.396834869948562	0.691489235021678	0.816341374643299	576	GTP cyclohydrolase I	NA	K01495	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00790 Folate biosynthesis	COG0302	H
LFTS_01425	270.772280624294	0.0716901704626211	0.180964747131934	0.396155447946746	0.69199035565892	0.816341374643299	1122	CRISPR-associated protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01764	49.5211825885262	-0.117479558701956	0.296943556618096	-0.395629257088236	0.69237855045137	0.816341374643299	498	Putative restriction endonuclease	NA	NA	NA	NA	NA	NA	NA
LFTS_02064	149.593113309633	-0.0823854176079941	0.208354538580066	-0.395409757663307	0.692540508998067	0.816341374643299	1098	DNA-binding response regulator%2C OmpR family%2C contains REC and winged-helix (wHTH) domain	NA	K02483	NA	              Overview	               01200 Carbon metabolism	COG0745	TK
LFTS_00050	3491.02267803829	-0.0926018036844923	0.234194669301788	-0.395405258200662	0.692543829092002	0.816341374643299	291	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01187	11.5590087383516	0.166931065105321	0.423335093772542	0.394323710840314	0.693342059798404	0.816894957658215	198	Rop-like protein	NA	K02660	 Cellular community - prokaryotes; Signal transduction	              Signal transduction	               02020 Two-component system	COG0840	NT
LFTS_00049	859.787168073839	0.0785631727326433	0.199551292180074	0.393699143084217	0.693803174098424	0.817051014120645	639	orotate phosphoribosyltransferase	NA	K00762	 Nucleotide metabolism	              Nucleotide metabolism	               00240 Pyrimidine metabolism	COG0461	F
LFTS_00852	4206.71777025461	-0.0557802825620901	0.142027824894292	-0.39274193351624	0.694510095700074	0.817496258480295	333	thioredoxin	Oxidative stress response	K03671	 Cardiovascular diseases; Immune system	              Immune system	               04621 NOD-like receptor signaling pathway	COG0526	O
LFTS_01267	56.7132661102334	0.111642068615806	0.285280379883333	0.391341559000526	0.695544783692699	0.818050855196273	927	hypothetical protein	NA	K07133	NA	              Membrane transport	               03070 Bacterial secretion system	COG1373	R
LFTS_02314	393.751160514071	0.0655632180347266	0.167589327706663	0.391213563130249	0.695639383702704	0.818050855196273	3420	hypothetical protein	NA	K09822	NA	              Energy metabolism	               00190 Oxidative phosphorylation	COG3002	S
LFTS_01037	46.7174915776222	0.120923300951287	0.311964156558245	0.387619213326868	0.698297848314198	0.820099908496374	633	hypothetical protein	NA	K07024	 Carbohydrate metabolism	              Carbohydrate metabolism	               00500 Starch and sucrose metabolism	COG0561	HR
LFTS_01229	119.565102133449	0.0852114545846213	0.220030178788791	0.38727166906689	0.698555097106965	0.820099908496374	333	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00619	378.701921991266	0.0674283653004202	0.17425601044776	0.386950011808255	0.698793215454058	0.820099908496374	699	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00975	224.196262811419	-0.0713721337337315	0.184757093794699	-0.386302535225195	0.699272623124794	0.820099908496374	1749	Type IV secretory pathway%2C TrbL components	NA	K07344	 Cellular community - prokaryotes	              Cellular community - prokaryotes	               02024 Quorum sensing	COG3846	U
LFTS_00328	328.026105989821	-0.0660444612191662	0.171010249541337	-0.386201770924858	0.69934724229248	0.820099908496374	219	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00636	105.410798024427	0.128864279594686	0.333687087150112	0.386182997655869	0.699361144815895	0.820099908496374	354	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00376	503.533160596025	-0.0682938106046053	0.177501065250747	-0.384751553508312	0.70042149571736	0.820932177495749	1047	DNA polymerase III%2C delta subunit	NA	K02340	 Replication and repair; Nucleotide metabolism	              Nucleotide metabolism	               00230 Purine metabolism	COG1466	L
LFTS_02452	13738.7006711738	0.0738627239142402	0.192183964833446	0.384333437902858	0.700731327693475	0.820932177495749	891	pyruvate ferredoxin oxidoreductase beta subunit	Reductive TCA cycle carbon dioxide fixation	K00170	 Carbohydrate metabolism; Overview; Energy metabolism; Xenobiotics biodegradation and metabolism	              Overview	               01200 Carbon metabolism	COG1013	C
LFTS_00981	22.7414424014414	0.143524247339808	0.374075178551195	0.383677548175429	0.701217455321784	0.821114740428618	375	hypothetical protein	NA	K02171	 Drug resistance	              Drug resistance	               01501 beta-Lactam resistance	COG3682	K
LFTS_02462	834.606603659307	-0.0634568454983919	0.165904699136114	-0.382489741573443	0.702098136568031	0.821758930088571	612	D-sedoheptulose 7-phosphate isomerase	NA	K03271	 Glycan biosynthesis and metabolism	              Glycan biosynthesis and metabolism	               00540 Lipopolysaccharide biosynthesis	COG0279	G
LFTS_00025	165.73214850558	-0.0939105034254338	0.246581535037935	-0.380849699110626	0.703314778802368	0.822795548283617	405	8-oxo-dGTP diphosphatase	NA	K03574	NA	              Cell growth and death	               04112 Cell cycle - Caulobacter	COG0494;COG1051	VF
LFTS_01468	18.4343210866151	-0.14705795786686	0.386901150335477	-0.380091808306457	0.703877266322338	0.823066267204766	690	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01317	305.626323176653	0.0655691994276214	0.172897421120734	0.379237579152986	0.704511447998525	0.823348291366385	1170	Glycosyltransferase involved in cell wall bisynthesis	Lipopolysaccharide synthesis	K13668	NA	              Cellular community - prokaryotes	               02026 Biofilm formation - Escherichia coli	COG0438	M
LFTS_02241	3523.48345474471	0.0658527419768403	0.173908379018903	0.378663422362659	0.704937818805889	0.823348291366385	1335	ATP-dependent RNA helicase RhlE	NA	K11927	 Folding, sorting and degradation	              Folding, sorting and degradation	               03018 RNA degradation	COG0513	L
LFTS_02463	694.652241760231	0.051315489645894	0.135601416992268	0.378428859993549	0.705112032308541	0.823348291366385	540	rfaE bifunctional protein%2C domain II	NA	K03272	 Glycan biosynthesis and metabolism	              Glycan biosynthesis and metabolism	               00540 Lipopolysaccharide biosynthesis	COG2870	M
LFTS_01075	68.2371754999016	-0.10327542342011	0.274763898329258	-0.375869697759026	0.707013769114062	0.82518132864674	1320	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_02442	1322.15825778168	-0.0683628071948087	0.182421967864663	-0.374750957875459	0.7078456904668	0.82576461121561	855	curved DNA-binding protein	NA	K05516	NA	              Amino acid metabolism	               00250 Alanine, aspartate and glutamate metabolism	COG2214	K
LFTS_02419	774.54354711483	0.0688856957951182	0.184095604903527	0.374184358345855	0.708267160373666	0.825868743287492	1212	RND family efflux transporter%2C MFP subunit	Cadmium/cobalt/zinc resistance	K15727	NA	              Membrane transport	               03070 Bacterial secretion system	COG0845	MV
LFTS_01606	1317.95765153346	-0.0486045309090719	0.130802731148069	-0.371586514153528	0.71020073141794	0.827735123443506	1176	dTDP-4-amino-4%2C6-dideoxygalactose transaminase	NA	K13017	 Carbohydrate metabolism	              Carbohydrate metabolism	               00520 Amino sugar and nucleotide sugar metabolism	COG0399	M
LFTS_01345	189.678912792055	0.0696067549908211	0.187773778260344	0.370694756401573	0.710864896310208	0.828120961680964	1089	lipopolysaccharide export system permease protein	Lipopolysaccharide synthesis	K11720	 Membrane transport	              Membrane transport	               02010 ABC transporters	COG0795	MN
LFTS_00456	114.903525681226	-0.100209623142365	0.272504630168978	-0.367735487944649	0.713070476334449	0.830301266588965	639	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01558	165.502480688418	0.0771254727623122	0.210321551458523	0.366702661840729	0.713840820819925	0.830809120111579	1110	L-threonine O-3-phosphate decarboxylase	NA	K04720	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00860 Porphyrin and chlorophyll metabolism	COG0079	E
LFTS_01540	584.812689725489	0.0586924532663303	0.160811499622213	0.364976717487329	0.715128785947579	0.831918653189369	621	5-formyltetrahydrofolate cyclo-ligase	NA	K01934	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00670 One carbon pool by folate	COG0212	H
LFTS_01827	3.96928285480494	0.147478101747991	0.406376641184678	0.36290988900853	0.716672199298696	0.833315820512033	339	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01736	537.732586068959	0.0999247270948214	0.275830500250244	0.362268592502156	0.71715132599884	0.833315820512033	1074	putative oxidoreductase	NA	K05882	NA	              Translation	               00970 Aminoacyl-tRNA biosynthesis	NA	
LFTS_00794	438.633987846468	0.0562112896125595	0.155270271897302	0.362022226957511	0.717335420714301	0.833315820512033	792	leader peptidase (prepilin peptidase) / N-methyltransferase	NA	K02654	NA	              Carbohydrate metabolism	               00650 Butanoate metabolism	COG1989	NU
LFTS_00168	632.464612752627	-0.0566860185663977	0.157496287038894	-0.359919713868549	0.718907174103653	0.834430071379202	876	Aromatic ring-opening dioxygenase%2C catalytic subunit%2C LigB family	NA	K15777	 Biosynthesis of other secondary metabolites	              Biosynthesis of other secondary metabolites	               00965 Betalain biosynthesis	NA	
LFTS_01488	222.519067021439	0.0749801000380976	0.208369972447076	0.359841195722872	0.718965894165024	0.834430071379202	528	5-(carboxyamino)imidazole ribonucleotide mutase	NA	K11808	 Nucleotide metabolism	              Nucleotide metabolism	               00230 Purine metabolism	NA	
LFTS_02511	480.128551293111	-0.0539173330723647	0.150337718385646	-0.358641421802452	0.719863355334783	0.83470953370397	618	precorrin-6Y C5%2C15-methyltransferase (decarboxylating)	NA	K00595	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00860 Porphyrin and chlorophyll metabolism	COG2241;COG2242	H
LFTS_00843	994.64761050412	0.0521750145181201	0.145487667289985	0.358621562157053	0.719878214103504	0.83470953370397	231	hypothetical protein	NA	K06960	NA	              Folding, sorting and degradation	               03060 Protein export	COG1837	R
LFTS_00913	81.486290218631	-0.097517430520326	0.272455258846001	-0.35792089656616	0.720402512100925	0.834928039665687	729	putative mobilization protein%2C MobD	NA	K03496	NA	              Membrane transport	               02010 ABC transporters	COG1192	N
LFTS_00983	14.8953307332509	-0.145849603965668	0.408187295774312	-0.357310493186707	0.720859375371775	0.835068223287154	528	conjugative transfer signal peptidase TraF	NA	K12062	NA	              Drug resistance	               01501 beta-Lactam resistance	NA	
LFTS_00117	1649.23306308298	0.0534186388471823	0.149763227847749	0.356687283085862	0.721325926788664	0.835087043102735	2619	DNA polymerase I	NA	K02335	 Nucleotide metabolism; Replication and repair	              Nucleotide metabolism	               00230 Purine metabolism	COG0258;COG0749	L
LFTS_00424	704.579756755933	-0.0640701547515696	0.179774683016497	-0.356391421063946	0.721547453171631	0.835087043102735	570	hypothetical protein	Extracellular polysaccharide production and export	K05790	NA	              Energy metabolism	               00920 Sulfur metabolism	COG3765	M
LFTS_00187	1421.1036329913	-0.0438881374490299	0.123356298406812	-0.355783515036201	0.722002695470342	0.835189738980279	1134	aminomethyltransferase	NA	K00605	 Carbohydrate metabolism; Metabolism of cofactors and vitamins; Amino acid metabolism; Overview	              Overview	               01200 Carbon metabolism	COG0404	E
LFTS_00912	36.0168938182832	0.133558752864746	0.375875958831777	0.35532667021282	0.722344877452146	0.835189738980279	384	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00253	375.969408883852	0.062474684754863	0.176163347508702	0.354640653906607	0.722858815807726	0.835189738980279	921	DNA processing protein	NA	K04096	NA	              Energy metabolism	               00910 Nitrogen metabolism	COG0758	L
LFTS_01237	71.7190264158969	-0.0970050870230665	0.273655462931535	-0.354478898334055	0.722980015400467	0.835189738980279	354	hypothetical protein	NA	K03790	NA	              Signal transduction	               02020 Two-component system	COG1670	JO
LFTS_01246	84.5852777690979	0.0977934823187273	0.276254958769952	0.35399720154947	0.723340980464949	0.835218614693852	861	Glycoside-hydrolase family GH114	putative pel operon	K01884	 Translation	              Translation	               00970 Aminoacyl-tRNA biosynthesis	COG2342	G
LFTS_01059	33.3547732069488	0.116593980317378	0.330015626184387	0.353298362460673	0.723864773045031	0.835303829060564	447	Heavy-metal resistance	Metal tolerance	NA	NA	NA	NA	NA	NA
LFTS_00294	1358.95268527476	0.0429235514136442	0.12159570301133	0.353002206086548	0.724086786655477	0.835303829060564	462	Response regulator receiver domain-containing protein	NA	K07713	 Signal transduction	              Signal transduction	               02020 Two-component system	COG2204	T
LFTS_01959	798.794842289252	0.0481445674243207	0.136949199618244	0.351550557130142	0.725175350623982	0.835832438006417	636	putative membrane protein	NA	K08976	NA	              Nucleotide metabolism	               00230 Purine metabolism	COG2322	S
LFTS_00647	1605.1192147102	0.0720700135564423	0.205038845478157	0.351494437009596	0.725217445205085	0.835832438006417	939	cysteine synthase	NA	K01738	 Energy metabolism; Amino acid metabolism; Overview	              Overview	               01200 Carbon metabolism	COG0031	E
LFTS_01614	372.646596215521	-0.0576608142701343	0.164382149381736	-0.3507729670588	0.725758679314099	0.836068617597243	771	ABC-2 type transport system ATP-binding protein	NA	K09687	NA	NA	NA	NA	
LFTS_02435	242.431170449185	-0.070303020768716	0.200823849344134	-0.350073066512354	0.726283863343073	0.836286097392719	1077	membrane fusion protein%2C Cu(I)/Ag(I) efflux system	Copper/silver resistance	K15727	NA	              Energy metabolism	               00910 Nitrogen metabolism	COG0845	MV
LFTS_00567	846.329797842189	0.0687743857234535	0.196957214955476	0.349184393874581	0.726950881605309	0.836666616514259	3762	AAA ATPase domain-containing protein	NA	K01768	 Cell growth and death; Aging; Cellular community - prokaryotes; Nucleotide metabolism	              Nucleotide metabolism	               00230 Purine metabolism	COG2114	T
LFTS_02297	2144.79172879619	0.0483869887965233	0.140349111325929	0.344761632898092	0.730273579097978	0.840101859156674	1572	SagB-type dehydrogenase domain-containing protein	NA	K00353	NA	NA	NA	NA	
LFTS_00564	838.319776505907	-0.0566993019386816	0.165260332663444	-0.343090813293658	0.731530142088481	0.841158155981482	1905	DNA adenine methylase	NA	K06223	 Replication and repair	              Replication and repair	               03430 Mismatch repair	COG0338	L
LFTS_01112	11.6107307721947	-0.143768520198565	0.421433816027353	-0.341141395709057	0.73299713907718	0.842113347148781	555	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01854	305.436634268362	0.0671694244803764	0.197112557042624	0.340766846557887	0.73327911080923	0.842113347148781	1320	L-2-hydroxyglutarate oxidase LhgO	NA	K15736	NA	              Biosynthesis of other secondary metabolites	               00965 Betalain biosynthesis	COG0579	G
LFTS_00286	174.693741113942	-0.0737979658970649	0.216647114264837	-0.340636736138805	0.7333770702241	0.842113347148781	303	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01163	17.6314047841915	-0.134868397754081	0.39660883932466	-0.340053938242358	0.733815908795038	0.842228231424037	1431	Mo-nitrogenase MoFe protein subunit NifD precursor	Nitrogenase genes	K02586	 Energy metabolism; Xenobiotics biodegradation and metabolism	              Energy metabolism	               00910 Nitrogen metabolism	COG2710	P
LFTS_01068	9.57216605287137	0.147191336908912	0.434130232822646	0.339048805589737	0.734572963750715	0.842405554605266	1050	hypothetical protein	NA	K03497	NA	              Translation	               03010 Ribosome	COG1475	D
LFTS_02282	504.95469720075	0.0610521865540539	0.180322599588185	0.338572018668114	0.734932164735194	0.842405554605266	1509	Acyl-CoA reductase	NA	K00131	 Carbohydrate metabolism; Overview	              Overview	               01200 Carbon metabolism	COG1012	C
LFTS_01841	227.77377503996	-0.14385066458702	0.424965967482276	-0.338499257809438	0.734986986298802	0.842405554605266	1482	Tetratricopeptide repeat-containing protein	NA	K12284	NA	              Nucleotide metabolism	               00230 Purine metabolism	NA	
LFTS_00296	163.945881917403	-0.071594989711917	0.213307855891042	-0.33564159844393	0.73714115090591	0.84448520790419	534	Carbonic anhydrase or acetyltransferase%2C isoleucine patch superfamily	Proton consuming reactions	K08279	NA	              Signal transduction	               02020 Two-component system	COG0663	R
LFTS_00891	105.611811884233	0.0749499660288372	0.225394961668185	0.332527246723353	0.739491169176437	0.846787216293239	405	putative N-acetyltransferase YhbS	NA	K03824	NA	              Metabolism of cofactors and vitamins	               00790 Folate biosynthesis	COG3153	R
LFTS_01073	8.3427628614381	-0.143266105442291	0.432443236240421	-0.331294591835494	0.740421975969539	0.847462722035117	411	hypothetical protein	NA	K06930	NA	              Energy metabolism	               00190 Oxidative phosphorylation	COG3413	R
LFTS_00075	438.204712459331	0.0675922745332957	0.204612501911383	0.330342837812372	0.741140928062235	0.847895235693841	1425	His Kinase A (phospho-acceptor) domain-containing protein	Role of potassium in the internal positive membrane potential	K02484	NA	              Replication and repair	               03430 Mismatch repair	COG0642	T
LFTS_01873	144.382362812371	0.0766370403616845	0.232963137322697	0.32896638173072	0.742181098555346	0.848694669277181	570	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase	NA	K00995	 Lipid metabolism	              Lipid metabolism	               00564 Glycerophospholipid metabolism	COG0558	I
LFTS_01963	1074.29983208451	-0.0483667873493812	0.147505884936618	-0.327897340300449	0.742989284795808	0.84895748100441	270	hypothetical protein	NA	K00127	 Carbohydrate metabolism; Energy metabolism; Overview	              Overview	               01200 Carbon metabolism	COG2864	C
LFTS_00676	3040.89255891458	0.0394268789364256	0.120292298175636	0.327758963245171	0.743093917403699	0.84895748100441	1566	ribonucrease Y	NA	K06950	NA	              Xenobiotics biodegradation and metabolism	               00627 Aminobenzoate degradation	COG1418	JR
LFTS_02422	2535.83255704371	-0.061570412588543	0.188442340202474	-0.326733432212676	0.743869511575701	0.849453195120438	3174	Multidrug efflux pump subunit AcrB	NA	K03296	NA	              Signal transduction	               02020 Two-component system	COG0841	V
LFTS_01992	1032.13527962235	0.0547657576083468	0.167978610622743	0.326028161593403	0.744403048352236	0.849672166301037	945	hydroxymethylbilane synthase	NA	K01749	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00860 Porphyrin and chlorophyll metabolism	COG0181	H
LFTS_02243	306.910888814794	0.0523743105214505	0.16263450658248	0.322036888862135	0.747424748618065	0.852729658129651	945	glutamate racemase	NA	K01776	 Metabolism of other amino acids	              Metabolism of other amino acids	               00471 D-Glutamine and D-glutamate metabolism	COG0796	M
LFTS_01143	51.0208500548924	-0.0931482442646393	0.290048653333383	-0.321146963428836	0.748099021980339	0.852896044137241	1197	hypothetical protein	NA	K03405	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00860 Porphyrin and chlorophyll metabolism	COG1239	H
LFTS_01353	1919.09354596177	-0.0412206623422657	0.128437753303866	-0.320938830537961	0.748256746686775	0.852896044137241	648	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_02000	278.742879010154	-0.0610828310983646	0.190595672337116	-0.320483830243135	0.748601586095883	0.85289804905333	882	diadenylate cyclase	NA	K07067	NA	              Membrane transport	               02060 Phosphotransferase system (PTS)	COG1623	T
LFTS_00481	259.066266302106	0.056264077816262	0.176259557819754	0.319211499859762	0.749566137153592	0.853605779644448	192	Proteolipid membrane potential modulator	NA	NA	NA	NA	NA	NA	NA
LFTS_00177	485.738098605997	0.0538746347080724	0.17064311947373	0.315715247554216	0.752218652341854	0.856234235220627	831	tRNA (adenine57-N1/adenine58-N1)-methyltransferase	NA	K07442	NA	              Cancers	               05206 MicroRNAs in cancer	COG2519	J
LFTS_01031	57.7958258146497	0.0926353318696203	0.295811612279863	0.313156509156846	0.754161758420556	0.858053149397484	414	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00343	96.0306031312878	-0.0774029583429074	0.248411941370385	-0.311591133324379	0.755351273582092	0.859013387980366	912	cation:H+ antiporter	Proton transporters	K07301	NA	              Amino acid metabolism	               00260 Glycine, serine and threonine metabolism	COG0530	P
LFTS_01604	1125.79084384031	-0.0456948575831754	0.147309133026693	-0.310197043756243	0.756411118474968	0.859825350036018	714	dethiobiotin synthetase	NA	K01935	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00780 Biotin metabolism	COG0132	H
LFTS_01164	12.4068007907736	-0.128978316832538	0.417171022085896	-0.309173720139127	0.75718938352482	0.860316639599042	1539	Mo-nitrogenase MoFe protein subunit NifK	Nitrogenase genes	K02591	 Energy metabolism; Xenobiotics biodegradation and metabolism	              Energy metabolism	               00910 Nitrogen metabolism	COG2710	P
LFTS_01574	580.633144425773	0.0434428177825967	0.14224254792798	0.305413664303824	0.760051116035427	0.863173629266364	1167	diaminohydroxyphosphoribosylaminopyrimidine deaminase	NA	K11752	 Cellular community - prokaryotes; Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00740 Riboflavin metabolism	COG0117;COG1985	H
LFTS_02032	51.901507937193	0.090806623186989	0.298304456242171	0.304409207729938	0.760816153701313	0.86331234688719	798	Type IV secretion-system coupling protein DNA-binding domain-containing protein	NA	K03205	 Membrane transport	              Membrane transport	               03070 Bacterial secretion system	COG3505	U
LFTS_00265	3613.94652609772	0.0643420985343557	0.211607477777104	0.304063444308571	0.761079556274851	0.86331234688719	288	DNA-binding transcriptional regulator%2C FrmR family	NA	NA	NA	NA	NA	NA	NA
LFTS_01259	95.2303512087715	0.082201377908935	0.270501088129538	0.303885572059401	0.761215070143492	0.86331234688719	252	prevent-host-death family protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00113	144.779415229176	0.0662884675363453	0.21992589868883	0.301412739161457	0.763099781298764	0.864902172449128	1002	AAA domain-containing protein	NA	K03631	NA	              Glycan biosynthesis and metabolism	               00514 Other types of O-glycan biosynthesis	COG0497	L
LFTS_00500	1326.60418304835	0.0710929968513106	0.236084650729358	0.301133498648372	0.763312697648185	0.864902172449128	1017	Fatty acid desaturase	NA	K10255	 Signal transduction	              Signal transduction	               02020 Two-component system	COG3239	I
LFTS_00448	434.572150097284	-0.0525074405768341	0.175841064200042	-0.298607386253647	0.76523962903452	0.866582247962914	636	two component transcriptional regulator%2C LuxR family	NA	K02479	NA	              Nucleotide metabolism	               00230 Purine metabolism	COG2197	TK
LFTS_00258	512.337749069393	-0.0453751818188174	0.152375000058151	-0.297786262848241	0.765866299831414	0.866582247962914	1335	ATP-dependent HslUV protease ATP-binding subunit HslU	Chaperones	K03667	NA	              Translation	               03010 Ribosome	COG1220	O
LFTS_00043	472.626720465109	-0.0519203465821339	0.17499065476172	-0.296703539128032	0.766692854819003	0.866582247962914	879	3-oxoacyl-[acyl-carrier-protein] synthase-3	NA	K00648	 Overview; Lipid metabolism	              Overview	               01212 Fatty acid metabolism	COG0332	I
LFTS_01404	152.406516507251	-0.0606924983487517	0.204627423845983	-0.296600021678586	0.766771894316806	0.866582247962914	684	SAM-dependent methyltransferase	NA	NA	NA	NA	NA	NA	NA
LFTS_01876	332.888272588267	-0.0539125683639771	0.181811516743248	-0.296529996172419	0.766825362822097	0.866582247962914	870	2-dehydro-3-deoxyphosphooctonate aldolase (KDO 8-P synthase)	NA	K01627	 Glycan biosynthesis and metabolism	              Glycan biosynthesis and metabolism	               00540 Lipopolysaccharide biosynthesis	COG2877	M
LFTS_00435	82.6214740413168	-0.0727932273133368	0.245550304792705	-0.296449346193194	0.766886945099924	0.866582247962914	687	Fic/DOC family protein	NA	K04095	NA	              Overview	               01210 2-Oxocarboxylic acid metabolism	COG2184	T
LFTS_02376	611.454965482944	-0.0549404795643119	0.18586663234747	-0.295590870025573	0.767542546896093	0.866929019347427	1209	Zn-dependent protease (includes SpoIVFB)	NA	K06402	NA	              Metabolism of cofactors and vitamins	               00860 Porphyrin and chlorophyll metabolism	COG1994	O
LFTS_00951	304.150671664103	-0.0503574821693395	0.171178384753658	-0.294181314082433	0.768619358427672	0.867751010468298	447	RDD family protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01550	1020.06550004114	0.0427627777657474	0.146430380718951	0.292034873881967	0.770259960093081	0.869208470627053	999	3'-5' exoribonuclease	NA	K03698	NA	              Overview	               01200 Carbon metabolism	COG3481	J
LFTS_00952	632.270261055142	0.0404987794638355	0.138992083135349	0.291374721137162	0.770764745814932	0.869383465560763	606	Thiopurine S-methyltransferase (TPMT)	NA	K00569	 Xenobiotics biodegradation and metabolism	              Xenobiotics biodegradation and metabolism	               00983 Drug metabolism - other enzymes	COG0500	QR
LFTS_00176	235.825661263205	0.0567876010569138	0.195881094631529	0.289908534377638	0.771886212396722	0.870253570983334	645	Methyltransferase domain-containing protein	NA	K00568	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00130 Ubiquinone and other terpenoid-quinone biosynthesis	COG2227	H
LFTS_02179	408.730312620242	-0.0498160429494601	0.173533473536013	-0.287068782375995	0.774059654669011	0.8720958316583	648	tRNA threonylcarbamoyladenosine biosynthesis protein TsaB	NA	K14742	NA	              Energy metabolism	               00910 Nitrogen metabolism	COG1214	J
LFTS_01309	728.727058073283	0.0556245601594842	0.193910438919699	0.286856965872369	0.774221842505981	0.8720958316583	819	Proline 4-hydroxylase (includes Rps23 Pro-64 3%2C4-dihydroxylase Tpa1)%2C contains SM-20 domain	NA	K07394	NA	              Glycan biosynthesis and metabolism	               00540 Lipopolysaccharide biosynthesis	COG3751	JO
LFTS_01894	824.005908587207	-0.0397220142012965	0.138948355405341	-0.285876101846756	0.774973018189148	0.872546613776368	468	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01706	3360.83915761723	-0.0467633660245882	0.164061127799546	-0.285036234065908	0.775616382075693	0.872875656785954	2034	transketolase	NA	K00615	 Carbohydrate metabolism; Energy metabolism; Overview; Metabolism of terpenoids and polyketides	              Overview	               01200 Carbon metabolism	COG0021	G
LFTS_00863	3865.15419289087	-0.0423388271088542	0.14930914384552	-0.283564864270197	0.776743866484322	0.873294360865648	2676	alanyl-tRNA synthetase	NA	K01872	 Translation	              Translation	               00970 Aminoacyl-tRNA biosynthesis	COG0013	J
LFTS_02087	60.5048186897452	0.0824910098102712	0.291275118047447	0.283206510611847	0.777018537833692	0.873294360865648	1275	OmpA family protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01222	828.609702943366	-0.0453314761700083	0.160093699211352	-0.283155904281796	0.777057328882432	0.873294360865648	1002	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01622	983.968569243887	-0.0562089969650246	0.198816987164067	-0.282717275655324	0.777393572242831	0.873294360865648	714	transcriptional regulator%2C TetR family	NA	K09017	NA	              Nucleotide metabolism	               00230 Purine metabolism	COG1309	K
LFTS_01625	661.43005296572	-0.0482802999985225	0.171627322232229	-0.281308939454258	0.778473454358768	0.873896470015176	768	phosphoribosylformylglycinamidine synthase	NA	K01952	 Nucleotide metabolism	              Nucleotide metabolism	               00230 Purine metabolism	COG0046;COG0047	F
LFTS_00597	280.512359902396	0.0481714547417907	0.171366816344996	0.281101416068861	0.778632615077882	0.873896470015176	1074	Phospho-N-acetylmuramoyl-pentapeptide- transferase	NA	K01000	 Glycan biosynthesis and metabolism; Drug resistance	              Glycan biosynthesis and metabolism	               00550 Peptidoglycan biosynthesis	COG0472	M
LFTS_01087	4.28640992205334	-0.114356557550272	0.410320957459103	-0.278700260055984	0.780474862920839	0.874958930313053	267	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_02533	279.005106975697	-0.0484696015954046	0.174187781188301	-0.278260629217199	0.780812296380021	0.874958930313053	237	hypothetical protein	NA	K02498	NA	              Lipid metabolism	               00564 Glycerophospholipid metabolism	COG3071	S
LFTS_01983	778.138116019786	-0.0466156854604396	0.167609236416711	-0.278121220864842	0.780919306238361	0.874958930313053	195	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_02060	18.1383562391295	0.110681337091954	0.398610829652112	0.277667661936207	0.781267486793607	0.874958930313053	705	biopolymer transport protein ExbB	NA	K03561	NA	              Replication and repair	               03440 Homologous recombination	COG0811	U
LFTS_00924	5375.97555664242	0.0563581131675188	0.203279752030882	0.277244106235219	0.781592674569496	0.874958930313053	1068	Site-specific recombinase XerD	NA	K04763	NA	              Translation	               00970 Aminoacyl-tRNA biosynthesis	COG0582	LX
LFTS_00485	240.887786049337	0.0593312779950747	0.214102625339738	0.277116069459343	0.781690983196014	0.874958930313053	1089	putative PurR-regulated permease PerM	NA	K06143	NA	              Metabolism of terpenoids and polyketides	               00523 Polyketide sugar unit biosynthesis	COG4452	V
LFTS_01525	401.052919871624	-0.0464170825276063	0.168878971713522	-0.274854128116945	0.783428310688538	0.876275050959293	1050	hypothetical protein	NA	K07027	NA	              Translation	               00970 Aminoacyl-tRNA biosynthesis	COG0392	S
LFTS_01378	193.245937575772	-0.0577738867244547	0.210539490974337	-0.274408788855184	0.783770489622306	0.876275050959293	675	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	NA	K03183	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00130 Ubiquinone and other terpenoid-quinone biosynthesis	COG2226	H
LFTS_00345	478.681672305719	0.0608322498978507	0.222152363630596	0.273831207121456	0.784214340085235	0.876275050959293	462	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01016	64.1200916225899	0.0767984463863859	0.281183647147075	0.273125578836439	0.78475668490762	0.876275050959293	711	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01257	13.8642239004358	0.111496625878894	0.408506376957846	0.27293729588559	0.784901416574127	0.876275050959293	363	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01144	34.7016571853525	-0.0907280700265655	0.332540868216779	-0.272832841608572	0.784981712987267	0.876275050959293	816	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_02299	63.7592066690645	-0.0792490111913678	0.291376360707903	-0.271981608250001	0.785636160952546	0.876611982104142	714	DNA replication and repair protein RadC	NA	K03630	NA	              Membrane transport	               02010 ABC transporters	COG2003	L
LFTS_01751	26.8487617818642	-0.0950055918839584	0.352278221032253	-0.26968908723784	0.7873994567011	0.878185307025094	963	Formate hydrogenlyase subunit 4	NA	K12138	NA	              Amino acid metabolism	               00260 Glycine, serine and threonine metabolism	COG0650	C
LFTS_00744	49.6402544116536	-0.0785048909722605	0.292456327557274	-0.268432868688356	0.788366142015316	0.878206030294384	540	Rad51 protein	NA	K04483	NA	              Overview	               01200 Carbon metabolism	COG0468	L
LFTS_00715	1479.13761874611	-0.0599507162232718	0.22341882700808	-0.268333322782613	0.788442758541955	0.878206030294384	321	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01684	918.263095298759	-0.0381748729568124	0.142290768611378	-0.26828776968009	0.788477819636792	0.878206030294384	693	rare lipoprotein A	NA	K03642	NA	              Metabolism of cofactors and vitamins	               00860 Porphyrin and chlorophyll metabolism	COG0797	M
LFTS_00009	4967.24310797065	0.0442161769976949	0.165413170279234	0.26730747571704	0.789232431339427	0.878652854594633	492	SsrA-binding protein	NA	K03664	NA	              Metabolism of cofactors and vitamins	               00790 Folate biosynthesis	COG0691	O
LFTS_00094	758.679915030896	0.0449842538616915	0.169078170483109	0.266055953486825	0.790196116738515	0.879331936531759	1710	phenylalanyl-tRNA synthetase beta subunit	NA	K01890	 Translation	              Translation	               00970 Aminoacyl-tRNA biosynthesis	COG0072	J
LFTS_02514	902.966025999948	0.0425669339663841	0.160297940713291	0.265548850951986	0.790586682516395	0.87937292739855	540	cob(I)alamin adenosyltransferase	NA	K00798	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00860 Porphyrin and chlorophyll metabolism	COG2096	H
LFTS_02491	1565.20067895487	-0.0413397923094266	0.156304734482465	-0.264482022545929	0.791408515697454	0.879524763473539	330	ferredoxin%2C 2Fe-2S	NA	K04755	NA	              Folding, sorting and degradation	               04122 Sulfur relay system	COG0633	C
LFTS_02115	208.347434795673	-0.0603182712927618	0.228204048850577	-0.264317270427821	0.791535453483093	0.879524763473539	453	putative oxidoreductase	NA	K15977	NA	              Amino acid metabolism	               00270 Cysteine and methionine metabolism	COG2259	S
LFTS_00641	10.8068612590833	0.111189785573292	0.421183043331599	0.263993974433943	0.791784561807635	0.879524763473539	216	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01284	153.4061815711	-0.063178071971262	0.241523925768405	-0.261581008052357	0.793644487698054	0.881197050655365	393	mRNA interferase MazF	NA	K07171	NA	              Amino acid metabolism	               00270 Cysteine and methionine metabolism	COG2337	V
LFTS_01314	682.218513103763	0.0391542183602326	0.151760551523963	0.257999974084505	0.796406927225304	0.883869473697368	1002	ADP-heptose:LPS heptosyltransferase	Lipopolysaccharide synthesis	K02843	 Glycan biosynthesis and metabolism	              Glycan biosynthesis and metabolism	               00540 Lipopolysaccharide biosynthesis	COG0859	M
LFTS_02079	1637.75818643763	-0.0354542388464568	0.138292581661369	-0.256371227006753	0.797664203108309	0.8842850164327	624	sugar ABC transporter substrate-binding protein	NA	NA	NA	NA	NA	NA	NA
LFTS_02128	1451.327731025	-0.0408734198643411	0.159853270908622	-0.255693359491567	0.798187623121044	0.8842850164327	2022	methionyl-tRNA synthetase	NA	K01874	 Translation; Metabolism of other amino acids	              Metabolism of other amino acids	               00450 Selenocompound metabolism	COG0143	J
LFTS_00789	615.123162679949	0.0406195687669825	0.159071985706874	0.255353377192596	0.798450176944138	0.8842850164327	930	fused signal recognition particle receptor	NA	K03110	 Cellular community - prokaryotes; Folding, sorting and degradation; Membrane transport	              Folding, sorting and degradation	               03060 Protein export	COG0552	U
LFTS_01312	1340.8544558916	-0.0365105874823617	0.143157530338935	-0.255037841152473	0.798693872360331	0.8842850164327	600	D-glycero-D-manno-heptose 1%2C7-bisphosphate phosphatase	Lipopolysaccharide synthesis	K03273	 Glycan biosynthesis and metabolism	              Glycan biosynthesis and metabolism	               00540 Lipopolysaccharide biosynthesis	COG0241	E
LFTS_00870	357.516920221222	-0.0473831597887763	0.185823370714312	-0.254990314763066	0.798730579735036	0.8842850164327	780	type III pantothenate kinase	NA	K03525	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00770 Pantothenate and CoA biosynthesis	COG1521	H
LFTS_00334	1463.41336608133	-0.0410214060595621	0.161025629059166	-0.25475078904669	0.79891558604499	0.8842850164327	477	peroxiredoxin Q/BCP	Oxidative stress response	K03564	NA	              Folding, sorting and degradation	               03050 Proteasome	COG1225	O
LFTS_01727	25.3786996928862	0.0998431236518701	0.394325990147897	0.253199449558024	0.800114091848159	0.88447060409713	216	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01061	98.3055231514073	0.0633921698856246	0.250447576694626	0.253115525102163	0.800178942136018	0.88447060409713	1191	diguanylate cyclase (GGDEF) domain-containing protein	Putative diguanylate cyclases (GGDEF domain-containing proteins)	K13590	 Cell growth and death	              Cell growth and death	               04112 Cell cycle - Caulobacter	COG2199	T
LFTS_01063	60.4801002644167	0.0689234712815575	0.272585806548681	0.252850550636607	0.800383702819765	0.88447060409713	495	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_02030	40.4177550941988	-0.081993804488013	0.324566344674454	-0.252625713766639	0.800557457684153	0.88447060409713	246	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01206	20.8391475936569	-0.100943118171112	0.400200343429975	-0.252231463136599	0.800862160025197	0.88447060409713	279	Plasmid maintenance system killer protein	NA	K07334	NA	              Translation	               00970 Aminoacyl-tRNA biosynthesis	COG3549	V
LFTS_01392	404.079278613825	0.0512310608315852	0.204061316725384	0.251057190327403	0.801769893230938	0.885079908779801	915	Nucleoside-diphosphate-sugar epimerase	NA	K01784	 Carbohydrate metabolism	              Carbohydrate metabolism	               00052 Galactose metabolism	COG1087	M
LFTS_02401	2001.48409459992	0.0317668561311722	0.12766995305137	0.248820144222896	0.803499908224781	0.886595992830362	1581	RNAse G	NA	K08301	NA	              Glycan biosynthesis and metabolism	               00550 Peptidoglycan biosynthesis	COG1530	J
LFTS_00374	677.301914665889	-0.0364220681859978	0.148049049972923	-0.246013521820364	0.805671765227012	0.888598051621274	1635	putative peptidoglycan lipid II flippase	NA	K03980	 Glycan biosynthesis and metabolism	              Glycan biosynthesis and metabolism	               00550 Peptidoglycan biosynthesis	COG0728	M
LFTS_02220	183.981479264824	-0.051745264669874	0.213332070712968	-0.242557363723787	0.808348313712659	0.891154726336883	342	putative addiction module killer protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00042	658.259942603932	-0.0352336219366468	0.146043429901775	-0.24125441288488	0.809357940676233	0.891872269734537	1374	two-component system%2C NtrC family%2C nitrogen regulation response regulator NtrX	Nitrate/nitrite regulation	K13599	 Signal transduction	              Signal transduction	               02020 Two-component system	COG2204	T
LFTS_01113	6.80240266870969	-0.103770170655904	0.434117536484756	-0.239037039360763	0.81107686184684	0.89245164463436	192	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_02062	35.6041625618662	0.0818440635522038	0.34257661807464	0.238907325351585	0.811177445212467	0.89245164463436	651	protein TonB	NA	K03832	NA	              Replication and repair	               03440 Homologous recombination	COG0810	M
LFTS_01252	34.7640910860405	-0.0845969596165624	0.354376189076245	-0.238720778156912	0.811322103862872	0.89245164463436	384	hypothetical protein	NA	K06996	NA	              Overview	               01210 2-Oxocarboxylic acid metabolism	COG3324	R
LFTS_01623	986.114813496855	-0.0486326190949038	0.203912730878618	-0.238497218321563	0.811495472576	0.89245164463436	729	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_02352	795.262022042564	0.0339318439313654	0.142869556935633	0.237502268916902	0.812267159212029	0.89245164463436	888	4-hydroxy-tetrahydrodipicolinate synthase	NA	K01714	 Amino acid metabolism; Overview; Biosynthesis of other secondary metabolites	              Overview	               01230 Biosynthesis of amino acids	COG0329	EM
LFTS_02453	19353.6418922309	-0.0473528470875135	0.199506666899287	-0.237349697749287	0.812385510149575	0.89245164463436	1221	pyruvate ferredoxin oxidoreductase alpha subunit	Reductive TCA cycle carbon dioxide fixation	K00169	 Carbohydrate metabolism; Overview; Energy metabolism; Xenobiotics biodegradation and metabolism	              Overview	               01200 Carbon metabolism	COG0674	C
LFTS_01124	367.785348574132	0.041080037398113	0.17308858376149	0.237335337232407	0.812396649962814	0.89245164463436	2526	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	NA	K02454	 Cellular community - prokaryotes; Membrane transport	              Membrane transport	               03070 Bacterial secretion system	COG2804	NUW
LFTS_01374	303.635525185473	0.039339827505441	0.166629346494285	0.236091830959621	0.813361412729783	0.892762763542813	297	phosphoribosylformylglycinamidine synthase	NA	NA	NA	NA	NA	NA	NA
LFTS_00903	1178.72269686337	-0.0337247693382003	0.142874588355749	-0.23604455996211	0.813398093091099	0.892762763542813	903	methylthioadenosine phosphorylase	NA	K00772	 Amino acid metabolism	              Amino acid metabolism	               00270 Cysteine and methionine metabolism	COG0005	F
LFTS_01167	3.62107026169891	-0.0974201892181932	0.415717779756705	-0.234342128150515	0.814719382764657	0.89381835196511	399	nitrogen fixation protein NifX	Nitrogenase genes	K02596	NA	              Energy metabolism	               00910 Nitrogen metabolism	NA	
LFTS_01360	2517.86372393078	0.0380713625503681	0.16284204576398	0.233793197400308	0.815145530931636	0.893891393866805	297	integration host factor subunit alpha	NA	K04764	NA	              Nucleotide metabolism	               00230 Purine metabolism	COG0776	L
LFTS_00925	490.568597254517	-0.0359396665221507	0.154347166757679	-0.232849538330528	0.815878243964121	0.894300403216404	969	hypothetical protein	NA	K09958	NA	              Translation	               00970 Aminoacyl-tRNA biosynthesis	COG3558	S
LFTS_01168	5.66050952160832	-0.0996833992621051	0.430196656573512	-0.231715885604683	0.816758692226382	0.894870916207486	459	putative nitrogen fixation protein	Nitrogenase genes	NA	NA	NA	NA	NA	NA
LFTS_01152	176.265289535521	0.0469834650546317	0.20526138081831	0.228895785789435	0.818949916078633	0.896656137219374	900	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_02091	10.6799964231125	-0.0967461195008331	0.424812247060138	-0.227738536660261	0.819849511615493	0.896656137219374	366	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01547	241.473356792587	-0.0430157919904516	0.188891621039526	-0.227727369555744	0.819858193597621	0.896656137219374	861	acyl-[acyl-carrier-protein] desaturase	NA	K03921	 Lipid metabolism; Overview	              Overview	               01212 Fatty acid metabolism	NA	
LFTS_01579	595.437810167863	0.0382964920712735	0.168432520077027	0.227369940518375	0.820136092195873	0.896656137219374	900	6-carboxyhexanoate--CoA ligase	NA	K01906	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00780 Biotin metabolism	COG1424	H
LFTS_01389	1217.25588926345	0.0549202555553662	0.241992749628272	0.226950004244878	0.820462618589613	0.896656137219374	2367	xylulose-5-phosphate/fructose-6-phosphate phosphoketolase	NA	K01632	NA	NA	NA	NA	
LFTS_02464	1588.53313299281	0.0297320769192766	0.131374591649877	0.226315275624337	0.82095621835289	0.896656137219374	3465	transcription-repair coupling factor	NA	K03723	 Replication and repair	              Replication and repair	               03420 Nucleotide excision repair	COG1197	LK
LFTS_02210	117.435797848499	0.0519358909945583	0.229609141212834	0.226192610277727	0.821051617831346	0.896656137219374	279	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00045	410.074146424419	0.0462059086654814	0.204534843925283	0.225907272221844	0.821273541612435	0.896656137219374	654	precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase	NA	K02304	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00860 Porphyrin and chlorophyll metabolism	COG1648	H
LFTS_01103	28.7180215589595	0.0798155556930203	0.354235093237176	0.225318036571775	0.821731869246854	0.896762698396698	651	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00377	405.92016924966	-0.0396363384306632	0.176628096612413	-0.224405625100744	0.82244169410124	0.89691952872402	720	Lipopolysaccharide-assembly	NA	K03643	NA	              Folding, sorting and degradation	               03018 RNA degradation	COG2980	M
LFTS_00058	219.583050364867	-0.0474414266517072	0.211905641824941	-0.223879960170666	0.822850709430572	0.89691952872402	1023	peptide/nickel transport system permease protein	NA	K02034	 Cellular community - prokaryotes	              Cellular community - prokaryotes	               02024 Quorum sensing	COG1173	EP
LFTS_00033	318.716776705819	-0.0404062408090742	0.181417396304386	-0.222725282316806	0.823749323122873	0.89691952872402	507	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00123	680.979262563103	-0.0421937371000208	0.189475220975425	-0.222687361876692	0.823778838160338	0.89691952872402	1008	thiamine-monophosphate kinase	NA	NA	NA	NA	NA	NA	NA
LFTS_01355	941.948744444184	0.0327819599056543	0.147245995441521	0.222633965747976	0.823820398985013	0.89691952872402	1062	threonine synthase	NA	K01733	 Metabolism of cofactors and vitamins; Overview; Amino acid metabolism	              Overview	               01230 Biosynthesis of amino acids	COG0498	E
LFTS_02201	1318.54210364563	-0.0404768158066511	0.182039814742258	-0.222351444731804	0.824040307162375	0.89691952872402	1272	hypothetical protein	NA	K09908	NA	              Translation	               03010 Ribosome	COG3105	S
LFTS_01714	675.477177664336	0.0364076804927351	0.164100435312671	0.221862181068351	0.824421171961014	0.896941371332639	957	HD-like signal output (HDOD) domain%2C no enzymatic activity	NA	K07181	 Cellular community - prokaryotes	              Cellular community - prokaryotes	               05111 Biofilm formation - Vibrio cholerae	COG2200;COG3434	T
LFTS_00007	361.726560775996	-0.0390657454071502	0.177652496004979	-0.219899783485481	0.825949204938751	0.897898532196409	726	7-cyano-7-deazaguanine synthase	NA	K06920	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00790 Folate biosynthesis	COG0603	J
LFTS_01820	5.29734744326203	-0.0943368402018774	0.430703121124035	-0.219029850435446	0.826626794995562	0.897898532196409	300	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_02221	207.501284125975	0.0532998398060493	0.243381473904238	0.218997111616724	0.826652297755665	0.897898532196409	282	putative addiction module antidote protein	NA	K15773	NA	              Lipid metabolism	               00564 Glycerophospholipid metabolism	COG1396	K
LFTS_00909	1603.16853221927	0.0326497144497553	0.149420287357339	0.218509246817827	0.82703235446521	0.897898532196409	1239	hypothetical protein	NA	K07729	NA	              Carbohydrate metabolism	               00030 Pentose phosphate pathway	COG1476	K
LFTS_00506	572.612788045067	0.0510439345505546	0.233703073875631	0.218413620771281	0.827106853873603	0.897898532196409	1572	maltose alpha-D-glucosyltransferase/ alpha-amylase	NA	K16146	 Carbohydrate metabolism	              Carbohydrate metabolism	               00500 Starch and sucrose metabolism	COG3281	G
LFTS_01221	205.779707838053	-0.0425631377841255	0.196298933341354	-0.216828166407356	0.82834226048032	0.898847166981264	246	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00112	117.194907245428	0.0518294112104619	0.240264629086464	0.21571802477763	0.829207550257181	0.899393529641951	912	DNA-binding transcriptional regulator%2C LysR family	NA	K11921	NA	              Glycan biosynthesis and metabolism	               00514 Other types of O-glycan biosynthesis	COG0583	K
LFTS_00825	270.762108659965	0.0407125556985488	0.189458129945341	0.214889462438453	0.829853500738494	0.899701614843392	387	2-iminobutanoate/2-iminopropanoate deaminase	NA	K07567	NA	NA	NA	NA	
LFTS_02385	360.838955988503	-0.0444299614427073	0.207400936866119	-0.214222568682935	0.830373497318124	0.89987293562897	768	phospholipid/cholesterol/gamma-HCH transport system permease protein	NA	K02066	 Membrane transport	              Membrane transport	               02010 ABC transporters	COG0767	M
LFTS_02266	528.05639092115	-0.0426752911927233	0.201365389645852	-0.211929623396442	0.832161939353161	0.901350919912333	636	glutamine amidotransferase	NA	K02501	 Overview; Amino acid metabolism	              Overview	               01230 Biosynthesis of amino acids	COG0118	E
LFTS_01089	28.7963168983585	0.0725337237584291	0.343516714301319	0.211150493523892	0.832769840191612	0.901350919912333	1137	ERF superfamily protein	NA	NA	NA	NA	NA	NA	NA
LFTS_02403	1782.45979836343	0.0383271023566825	0.181875000230337	0.210733208567109	0.833095459764685	0.901350919912333	1935	penicillin-binding protein 2	NA	K05515	 Drug resistance; Glycan biosynthesis and metabolism	              Glycan biosynthesis and metabolism	               00550 Peptidoglycan biosynthesis	COG0768	DM
LFTS_01919	710.965540668195	-0.0309407183066847	0.146906446856793	-0.210615115733118	0.833187616234329	0.901350919912333	1317	dihydroorotase	NA	K01465	 Nucleotide metabolism	              Nucleotide metabolism	               00240 Pyrimidine metabolism	COG0044;COG0418	F
LFTS_01481	349.17772787313	-0.0472687031399532	0.225060512530539	-0.210026639540063	0.833646881365012	0.901455479370778	504	putative transposase	NA	K07496	NA	              Carbohydrate metabolism	               00500 Starch and sucrose metabolism	COG0675	X
LFTS_00980	56.7323534364175	0.0590070780236221	0.284264146270974	0.207578334438891	0.835558222496835	0.902840160896792	999	type IV secretion system protein VirB11	NA	K03196	 Infectious diseases; Membrane transport	              Membrane transport	               03070 Bacterial secretion system	COG0630	U
LFTS_01549	1084.10019911874	-0.0350351296032406	0.168879801471256	-0.20745600893665	0.835653745061753	0.902840160896792	2838	FAD/FMN-containing dehydrogenase	NA	K00102	 Carbohydrate metabolism	              Carbohydrate metabolism	               00620 Pyruvate metabolism	NA	
LFTS_00186	295.083776140261	-0.0381171538651051	0.184317690690067	-0.20680138581597	0.83616497382284	0.902880500311381	186	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_02088	21.5730542226549	0.0822817317226692	0.398500974027861	0.206478119466068	0.836417454632787	0.902880500311381	381	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01326	759.232579697684	0.0332200132653368	0.161996531430138	0.205066200936921	0.837520402986113	0.903678698708107	705	serine O-acetyltransferase	NA	K00640	 Energy metabolism; Amino acid metabolism; Overview; Cellular community - prokaryotes	              Overview	               01200 Carbon metabolism	COG1045	E
LFTS_00490	357.814480364084	-0.0351838959648301	0.173253214168528	-0.203077883049291	0.839074158307982	0.904962411086179	552	dTDP-4-dehydrorhamnose 3%2C5-epimerase	Extracellular polysaccharide production and export	K01790	 Biosynthesis of other secondary metabolites; Metabolism of terpenoids and polyketides	              Metabolism of terpenoids and polyketides	               00523 Polyketide sugar unit biosynthesis	COG1898	M
LFTS_02072	214.348337319478	-0.0837487305627224	0.418018211698552	-0.200347085889924	0.841209139745827	0.906871605120609	3129	multidrug efflux pump	NA	K03296	NA	              Membrane transport	               02010 ABC transporters	COG0841	V
LFTS_01082	34.1542042041005	-0.0672728606470974	0.338609115784476	-0.198674097982396	0.842517686915751	0.907888586767472	696	hypothetical protein	NA	K06871	NA	              Metabolism of cofactors and vitamins	               00730 Thiamine metabolism	COG0641	O
LFTS_01078	27.4398779671385	0.0689345678807111	0.347962913362343	0.198108951366687	0.842959821458162	0.907971454135611	651	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01400	636.579365470243	-0.0304860833777907	0.155150256866617	-0.19649392784441	0.844223584909544	0.908938861881822	1668	sulfate-transporting ATPase	NA	K06020	NA	              Transport and catabolism	               04144 Endocytosis	NA	
LFTS_01571	408.864458191093	0.0337682575978993	0.173326681258177	0.194824347600587	0.845530460875584	0.909372768770979	756	precorrin-2/cobalt-factor-2 C20-methyltransferase	NA	K03394	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00860 Porphyrin and chlorophyll metabolism	COG2243	H
LFTS_01912	11256.8649531477	-0.0352270738044212	0.18093005012302	-0.194699961562323	0.845627842004123	0.909372768770979	324	iron-sulfur cluster insertion protein	NA	K15724	NA	              Nucleotide metabolism	               00240 Pyrimidine metabolism	COG0316	O
LFTS_01539	736.718523439394	-0.027007493824654	0.138800951137617	-0.19457715241358	0.845723990908489	0.909372768770979	1902	Citrate transporter	NA	K14445	NA	              Lipid metabolism	               00561 Glycerolipid metabolism	COG0471	G
LFTS_01235	242.909441399752	-0.0401345197630827	0.208049771543413	-0.19290826164021	0.847030814711853	0.910384178717539	369	Glyoxalase-like domain protein	NA	K08234	NA	              Signal transduction	               02020 Two-component system	COG0346	Q
LFTS_00995	504.695310837012	0.0292746696114644	0.152803187280144	0.191584155622312	0.848067954585249	0.911104984917429	441	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00277	345.337495844705	-0.0352066882846234	0.184221340706061	-0.191110802633873	0.84843878434749	0.911109640556311	1257	putative arabinose efflux permease%2C MFS family	NA	K05820	NA	              Carbohydrate metabolism	               00520 Amino sugar and nucleotide sugar metabolism	COG0477	GEPR
LFTS_00640	33.7600344557846	0.064410370845454	0.345382205906124	0.186490125269977	0.852060421920445	0.914603717139131	786	putative DNA primase/helicase	NA	K02316	 Replication and repair	              Replication and repair	               03030 DNA replication	COG0358	L
LFTS_01279	166.043841341208	-0.0362049573326885	0.196168739845675	-0.184560278876088	0.853573943501333	0.915518743705621	714	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01524	612.97042838134	0.0282479953055931	0.153201975755055	0.184384014412171	0.853712209473222	0.915518743705621	417	nucleoside diphosphate kinase	NA	K00940	 Nucleotide metabolism; Signal transduction	              Nucleotide metabolism	               00230 Purine metabolism	COG0105	F
LFTS_02090	54.5566576463302	-0.0524341689394673	0.284976662084491	-0.183994606982664	0.854017685701261	0.915518743705621	840	Peptidase C39 family protein	NA	K06992	NA	              Metabolism of cofactors and vitamins	               00770 Pantothenate and CoA biosynthesis	COG3271	R
LFTS_02021	29.3665778973417	-0.0653263302299916	0.360087615490145	-0.181417875594168	0.856039588983409	0.917290697505498	324	hypothetical protein	NA	K07733	NA	              Overview	               01230 Biosynthesis of amino acids	COG3311	KX
LFTS_00664	1024.78185086006	0.0367680391013318	0.204323477892484	0.179950143177767	0.857191709118561	0.918129508344999	1035	4-hydroxythreonine-4-phosphate dehydrogenase	NA	K00097	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00750 Vitamin B6 metabolism	COG1995	H
LFTS_02116	106.922154898068	-0.0422074461648579	0.235511653036058	-0.179215956496198	0.857768135089678	0.918351241960784	480	DNA-binding transcriptional regulator%2C MarR family	NA	K15973	NA	              Amino acid metabolism	               00270 Cysteine and methionine metabolism	COG1846	K
LFTS_01871	180.140971904517	0.0429304400773601	0.242786467661415	0.176823858804314	0.859646747733627	0.918941873241029	171	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01296	546.744639224074	0.0282534064000352	0.160402008411945	0.176141225909558	0.860182993626031	0.918941873241029	966	putative dehydrogenase	NA	K03810	NA	              Glycan biosynthesis and metabolism	               00540 Lipopolysaccharide biosynthesis	COG0673	R
LFTS_01256	61.0211278775758	-0.059597194718783	0.339139360419658	-0.175730692671698	0.860505521255226	0.918941873241029	264	transcriptional regulator%2C y4mF family	NA	K15773	NA	              Overview	               01210 2-Oxocarboxylic acid metabolism	COG1396	K
LFTS_00362	132.102545081881	-0.0373759291005956	0.213085483625421	-0.175403450599657	0.860762629433432	0.918941873241029	888	branched-chain amino acid aminotransferase	NA	K02619	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00790 Folate biosynthesis	COG0115	EH
LFTS_02285	995.660137212408	-0.0331032208335951	0.189277104015439	-0.174892895819533	0.861163792556062	0.918941873241029	654	phosphate transport system protein	NA	K02039	NA	              Overview	               01200 Carbon metabolism	COG0704	P
LFTS_02512	1028.63531916776	-0.0241275414688757	0.137964701080315	-0.174881989957925	0.861172362114829	0.918941873241029	1137	cobalt-precorrin 5A acetaldehyde-lyase	NA	K02189	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00860 Porphyrin and chlorophyll metabolism	COG2073	H
LFTS_02211	242.497990810056	-0.0458097968960176	0.262000631610351	-0.174846131532027	0.861200538902278	0.918941873241029	255	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01705	4533.68830204703	-0.0319812906729792	0.184401734802729	-0.173432699574071	0.862311323997526	0.918941873241029	2934	transaldolase	NA	K13810	 Carbohydrate metabolism; Overview	              Overview	               01200 Carbon metabolism	NA	
LFTS_01762	75.2141912623721	0.0444664329541157	0.256454623159094	0.173389086951771	0.862345602540498	0.918941873241029	402	PIN domain nuclease%2C a component of toxin-antitoxin system (PIN domain)	NA	K07062	NA	              Amino acid metabolism	               00260 Glycine, serine and threonine metabolism	COG1487	R
LFTS_01544	533.753850002386	0.0343674920076278	0.198258053612716	0.17334726827674	0.862378471324592	0.918941873241029	846	ketopantoate hydroxymethyltransferase	NA	K00606	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00770 Pantothenate and CoA biosynthesis	COG0413	H
LFTS_01953	487.012566462905	0.028474079838062	0.164269309231416	0.173337794937391	0.862385917245101	0.918941873241029	825	indole-3-glycerol phosphate synthase	NA	K01609	 Overview; Amino acid metabolism	              Overview	               01230 Biosynthesis of amino acids	COG0134	E
LFTS_01375	562.95849288698	-0.0248596872839233	0.144725179469431	-0.171771680470945	0.863617030283095	0.919239481836594	1341	hypothetical protein	NA	K08509	 Transport and catabolism; Folding, sorting and degradation	              Folding, sorting and degradation	               04130 SNARE interactions in vesicular transport	NA	
LFTS_01393	1062.45210781604	-0.0228730812639961	0.133278066718802	-0.171619245590162	0.863736876149914	0.919239481836594	2589	starch phosphorylase	NA	K00688	 Endocrine system; Endocrine and metabolic diseases; Cellular community - prokaryotes; Carbohydrate metabolism	              Carbohydrate metabolism	               00500 Starch and sucrose metabolism	COG0058	G
LFTS_01015	12.5593777713468	-0.07393021557997	0.430900628680094	-0.171571380172798	0.863774509078956	0.919239481836594	165	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00617	664.598922267524	-0.0293749809308361	0.173303738437414	-0.169499984222466	0.865403384769556	0.920578868009036	789	hypothetical protein	NA	K01243	 Amino acid metabolism; Overview	              Overview	               01230 Biosynthesis of amino acids	COG0775	F
LFTS_01430	39.4068198562065	0.0541837737399014	0.321719327414797	0.168419392690205	0.866253352850682	0.921088894434044	1479	sulfate permease%2C SulP family	NA	K03321	NA	              Metabolism of cofactors and vitamins	               00860 Porphyrin and chlorophyll metabolism	COG0659	P
LFTS_00149	914.95091910648	-0.0249305319988105	0.15153822756785	-0.164516455015604	0.869324594005596	0.923959358998679	1284	Tetratricopeptide repeat-containing protein	NA	K02656	NA	              Folding, sorting and degradation	               04122 Sulfur relay system	COG3063	NW
LFTS_02147	1052.41606316064	-0.0320781947759374	0.197626119259736	-0.162317586845784	0.871055766029556	0.925225371138908	1734	methyl-accepting chemotaxis protein	Chemotaxis	K03406	 Signal transduction; Cell motility	              Signal transduction	               02020 Two-component system	COG0840	NT
LFTS_01161	21.8581557007161	-0.0608411495987952	0.37542798625896	-0.162058109213064	0.871260094061216	0.925225371138908	1131	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01344	280.143451453037	0.0282305830088281	0.177784129876945	0.158791355720942	0.87383325953444	0.927561692229982	1071	ferrochelatase	NA	K01772	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00860 Porphyrin and chlorophyll metabolism	COG0276	H
LFTS_01247	109.994295058796	0.0364117540205294	0.230048005609619	0.15827893801574	0.87423700395815	0.927594191993155	567	TolB amino-terminal domain-containing protein	putative pel operon	K07337	NA	              Translation	               00970 Aminoacyl-tRNA biosynthesis	COG3417	M
LFTS_00971	228.080822730058	-0.0295407631851185	0.190047398614363	-0.15543892418681	0.876475299995826	0.929528733111174	1452	type IV secretion system protein VirB10	NA	K03195	 Membrane transport	              Membrane transport	               03070 Bacterial secretion system	COG2948	U
LFTS_01321	761.538759878248	0.0284458087212842	0.183501463358224	0.155016794965572	0.876808076888859	0.929528733111174	1416	adenosylmethionine-8-amino-7-oxononanoate aminotransferase	NA	K00833	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00780 Biotin metabolism	COG0161	H
LFTS_01352	3506.54217338549	-0.0243858252443545	0.157900900799771	-0.15443753088703	0.877264763249186	0.929616454150672	1200	alanine-synthesizing transaminase	NA	K14261	NA	              Overview	               01230 Biosynthesis of amino acids	COG0436	E
LFTS_00037	321.21810797673	-0.0285589610395245	0.186839419881857	-0.152852974268402	0.878514221109772	0.930543823467785	435	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01552	441.694178956413	0.0250730347780342	0.164608922637608	0.152318807366435	0.878935491864287	0.930593540363976	333	hypothetical protein	NA	K09780	NA	              Overview	               01230 Biosynthesis of amino acids	COG2350	R
LFTS_00973	176.383899999893	0.0319082823815088	0.210975461375003	0.151241676039247	0.879785075668041	0.931096508348552	1077	type IV secretion system protein VirB9	NA	K03204	 Membrane transport	              Membrane transport	               03070 Bacterial secretion system	COG3504	U
LFTS_02414	2301.3900045815	-0.0207795255891422	0.138649828172627	-0.149870546996066	0.880866749319596	0.931844569705751	2070	hypothetical protein	NA	K06888	NA	              Membrane transport	               03070 Bacterial secretion system	COG1331	R
LFTS_02280	960.572164695221	0.0267162037300096	0.179849969320732	0.148547168681279	0.881910963613602	0.932510050787659	1008	fructose-1%2C6-bisphosphatase I	NA	K03841	 Carbohydrate metabolism; Overview; Signal transduction; Energy metabolism; Endocrine system	              Overview	               01200 Carbon metabolism	COG0158	G
LFTS_01594	591.981775722059	-0.0234390922985001	0.158241188248487	-0.148122575152137	0.882246033569016	0.932510050787659	639	thiamine-phosphate pyrophosphorylase	NA	K00788	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00730 Thiamine metabolism	COG0352	H
LFTS_02089	24.9689242290897	0.0576801108078188	0.396660894743192	0.145414159984594	0.884383885439889	0.934372434850643	741	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01033	39.2691914890092	0.0454371307711139	0.316103548339967	0.143741286707249	0.885704767640978	0.93537045554608	666	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01258	5.42575952712191	0.0612032637110527	0.430181307221536	0.142273182687443	0.886864228140901	0.93602105323172	150	hypothetical protein	NA	K07473	NA	              Overview	               01210 2-Oxocarboxylic acid metabolism	COG3077	V
LFTS_01924	600.847136260774	0.0204366407922521	0.144254089224018	0.141671136687953	0.887339774531523	0.93602105323172	522	tRNA threonylcarbamoyladenosine biosynthesis protein TsaE	NA	K06925	NA	              Metabolism of cofactors and vitamins	               00860 Porphyrin and chlorophyll metabolism	COG0802	J
LFTS_01492	654.868331985951	-0.0200731141724568	0.142383325118468	-0.140979388954115	0.887886224937762	0.93602105323172	1365	adenylate cyclase	NA	K01768	 Cell growth and death; Aging; Cellular community - prokaryotes; Nucleotide metabolism	              Nucleotide metabolism	               00230 Purine metabolism	COG2114	T
LFTS_01244	17.2773492225614	0.0557711736339219	0.397744270729462	0.140218672494359	0.888487219135062	0.93602105323172	903	hypothetical protein	putative pel operon	K05384	 Energy metabolism	              Energy metabolism	               00196 Photosynthesis - antenna proteins	NA	
LFTS_00680	1515.73245526905	-0.0190795081268055	0.136131797615774	-0.140154677018638	0.888537780860929	0.93602105323172	912	farnesyl-diphosphate synthase	NA	K13789	 Metabolism of terpenoids and polyketides	              Metabolism of terpenoids and polyketides	               00900 Terpenoid backbone biosynthesis	COG0142	H
LFTS_01210	184.580595162243	-0.0389499643295538	0.278572267230819	-0.139819963834665	0.888802239381166	0.93602105323172	186	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_02326	71.1587849912394	-0.037407524509815	0.267914599595906	-0.139624807928484	0.888956438728918	0.93602105323172	2901	iron complex outermembrane recepter protein	NA	K02014	NA	              Glycan biosynthesis and metabolism	               00540 Lipopolysaccharide biosynthesis	COG1629	P
LFTS_01354	1239.29681239981	0.0214015831314928	0.15430672666961	0.138695075667805	0.889691109538152	0.936086304374625	1332	homoserine dehydrogenase	NA	K00003	 Amino acid metabolism; Overview	              Overview	               01230 Biosynthesis of amino acids	COG0460	E
LFTS_00969	148.361261383023	0.0309752122187214	0.223646936708978	0.138500498484484	0.88984487567961	0.936086304374625	606	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01159	3.28875797363109	-0.0568403363285867	0.411537914416489	-0.138116888717725	0.890148038431864	0.936086304374625	240	ORF6N domain-containing protein	NA	K00373	 Signal transduction	              Signal transduction	               02020 Two-component system	COG2180	CPO
LFTS_02073	144.34181717818	0.0464541994865308	0.338005493830719	0.137436226139555	0.890685998396361	0.936255979709663	1158	membrane fusion protein%2C multidrug efflux system	NA	K03585	 Drug resistance	              Drug resistance	               01501 beta-Lactam resistance	COG0845	MV
LFTS_01429	12.4821550053034	-0.0568167200393764	0.416770800011023	-0.136326057482611	0.891563525286962	0.9367823008721	864	Nucleotide-binding universal stress protein%2C UspA family	NA	K06149	NA	              Overview	               01230 Biosynthesis of amino acids	COG0589	T
LFTS_01978	1127.03793411003	-0.0268160790670947	0.198813109486239	-0.134880839278613	0.89270608913956	0.937586538910412	996	homoserine kinase	NA	K00872	 Overview; Amino acid metabolism	              Overview	               01230 Biosynthesis of amino acids	COG0083	E
LFTS_00573	5787.8457304	-0.0189080107842631	0.143210541272085	-0.132029462470502	0.89496098805292	0.939109861324374	1428	PilZ domain-containing protein	c-di-GMP effector proteins; Extracellular polysaccharide production and export	K02481	NA	              Nucleotide metabolism	               00230 Purine metabolism	COG2204	T
LFTS_01186	27.8733488480529	0.0470699174176043	0.356523584519309	0.132024694750748	0.894964759132135	0.939109861324374	630	response regulator receiver and ANTAR domain protein	NA	K07183	NA	              Signal transduction	               02020 Two-component system	COG3707	TK
LFTS_00012	153.754302279796	0.026542758384136	0.202732933964796	0.130924748461171	0.895834836752554	0.939109861324374	288	hypothetical protein	NA	K05663	 Membrane transport	              Membrane transport	               02010 ABC transporters	NA	
LFTS_02240	342.894917409998	-0.0241868082809996	0.185144670618828	-0.130637345380548	0.896062198533024	0.939109861324374	99	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_02071	434.200678003323	-0.0560603367920163	0.430876956462091	-0.130107530586748	0.896481352220847	0.939109861324374	1503	efflux transporter%2C outer membrane factor (OMF) lipoprotein%2C NodT family	Copper/silver resistance	K07796	 Signal transduction	              Signal transduction	               02020 Two-component system	COG1538	M
LFTS_01857	58819.7167159967	-0.0248482915072275	0.191241235145501	-0.12993166190504	0.896620494039109	0.939109861324374	1383	cytochrome c oxidase cbb3-type subunit 1	Cytochrome cbb3 oxidase	K00404	 Energy metabolism; Signal transduction	              Energy metabolism	               00190 Oxidative phosphorylation	COG3278	C
LFTS_02430	438.650653738317	0.0200190732716915	0.154344588809983	0.129703758492871	0.896800808843147	0.939109861324374	201	hypothetical protein	NA	K16263	NA	              Amino acid metabolism	               00360 Phenylalanine metabolism	COG0531	E
LFTS_01179	7.78166600577747	0.0554640278556299	0.433842183666616	0.127843787311957	0.898272597091266	0.939987840479289	210	nitrogen fixation protein NifT	Nitrogenase genes	K02593	NA	              Overview	               01210 2-Oxocarboxylic acid metabolism	NA	
LFTS_01913	4047.95559417637	0.0217836366009647	0.17059977574219	0.127688541829528	0.898395458157196	0.939987840479289	198	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00159	464.442244828775	0.0194055655911381	0.153908097978815	0.126085409708651	0.899664316661677	0.940919432570858	369	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00978	68.1053387254044	-0.0331071790585295	0.264019948778387	-0.125396505876604	0.900209654188808	0.941093860518662	336	type IV secretion system protein VirB3	NA	K03198	 Membrane transport	              Membrane transport	               03070 Bacterial secretion system	COG3702	U
LFTS_00446	920.285941826849	-0.0176543498703436	0.142164675850722	-0.124182394569529	0.901170861429772	0.941702716063226	1293	putative arabinose efflux permease%2C MFS family	NA	K08153	NA	              Glycan biosynthesis and metabolism	               00540 Lipopolysaccharide biosynthesis	COG0477	GEPR
LFTS_01743	343.389246869739	0.0240384115568217	0.197863795889793	0.121489691677657	0.903303179075424	0.94336611398496	636	DNA-3-methyladenine glycosylase	NA	K03652	 Replication and repair	              Replication and repair	               03410 Base excision repair	COG2094	L
LFTS_00079	498.842718065787	-0.0248591322997025	0.205084817482907	-0.121213908493126	0.903521607963874	0.94336611398496	1203	putative arabinose efflux permease%2C MFS family	NA	K08153	NA	              Xenobiotics biodegradation and metabolism	               00364 Fluorobenzoate degradation	COG0477	GEPR
LFTS_01869	1167.94019962656	0.0168008028435601	0.13973799265247	0.12023074415663	0.904300364102188	0.943412449039748	1521	Signal transduction histidine kinase	NA	K02484	NA	              Metabolism of terpenoids and polyketides	               00900 Terpenoid backbone biosynthesis	COG0642	T
LFTS_00024	1045.4412449838	0.0266401171011979	0.221632168196989	0.120199686344808	0.904324966235607	0.943412449039748	1431	HD domain-containing protein	NA	K07814	NA	              Cell growth and death	               04112 Cell cycle - Caulobacter	COG3437	T
LFTS_01080	42.1480244301766	0.0402290817119028	0.338400309336379	0.11888015643601	0.905370303132583	0.943782210289588	708	Methyltransferase domain-containing protein	NA	K00568	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00130 Ubiquinone and other terpenoid-quinone biosynthesis	COG2227	H
LFTS_01064	85.800812632668	-0.0299705171450403	0.252290151762917	-0.118793844847358	0.905438685253688	0.943782210289588	1263	YqaJ-like viral recombinase domain protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00669	1580.21770058184	0.0163493839382247	0.138289050555289	0.118226163767667	0.905888459645344	0.943855285280103	1689	ribonuclease J	NA	K12574	 Folding, sorting and degradation	              Folding, sorting and degradation	               03018 RNA degradation	COG0595	J
LFTS_01508	256.779317898077	0.0218567064445764	0.187398877106219	0.116632003254683	0.907151675861995	0.944504134451287	708	general secretion pathway protein J	NA	K02459	 Cellular community - prokaryotes; Membrane transport	              Membrane transport	               03070 Bacterial secretion system	COG2165	NUW
LFTS_01788	106.72055981777	0.0281845235461217	0.242484077121869	0.116232471346795	0.907468302739936	0.944504134451287	984	Transposase	NA	K07497	NA	              Carbohydrate metabolism	               00500 Starch and sucrose metabolism	COG2801	X
LFTS_01765	141.401124749303	-0.0267840495732794	0.230893097957686	-0.116001949864209	0.907650996461836	0.944504134451287	255	Plasmid stability protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01781	1248.83393963925	0.0216234820876084	0.1889969576404	0.114411799838338	0.908911360500822	0.945419933977006	1176	CDP-6-deoxy-D-xylo-4-hexulose-3-dehydrase	NA	K12452	 Carbohydrate metabolism	              Carbohydrate metabolism	               00520 Amino sugar and nucleotide sugar metabolism	COG0399	M
LFTS_01328	269.969153764405	-0.0207878781587184	0.184178577954343	-0.112868056587295	0.910135161614777	0.946296951808589	1641	Dolichyl-phosphate-mannose-protein mannosyltransferase	Lipopolysaccharide synthesis	K07264	 Drug resistance	              Drug resistance	               01503 Cationic antimicrobial peptide (CAMP) resistance	COG1807	M
LFTS_01305	721.696684796026	0.0154685912530571	0.138389123248461	0.111776062236373	0.911000968129009	0.946801173398293	1116	heptosyltransferase-1	Lipopolysaccharide synthesis	K02841	 Glycan biosynthesis and metabolism	              Glycan biosynthesis and metabolism	               00540 Lipopolysaccharide biosynthesis	COG0859	M
LFTS_01014	37.3662038022907	0.0357829358712217	0.323816782585861	0.110503648345446	0.912009956630087	0.947453720092936	219	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_02423	1572.56665889312	-0.0240849173035044	0.221134950811211	-0.108915018703065	0.913269894309571	0.94836631464227	1092	RND family efflux transporter%2C MFP subunit	Cadmium/cobalt/zinc resistance	K15727	NA	              Signal transduction	               02020 Two-component system	COG0845	MV
LFTS_00979	66.0517852396267	0.0300704547197906	0.284181661105226	0.105814198575805	0.915729771203155	0.950523679002523	330	TrbC/VIRB2 family protein	NA	K03197	 Infectious diseases; Membrane transport	              Membrane transport	               03070 Bacterial secretion system	COG3838	U
LFTS_02445	1098.20356915682	-0.0152603568537918	0.150752598427473	-0.101227819705765	0.91936961321053	0.953530877752372	1425	glutamyl-tRNA synthetase	NA	K09698	 Translation	              Translation	               00970 Aminoacyl-tRNA biosynthesis	COG0008	J
LFTS_01782	735.786973444136	-0.0163909466345281	0.161970544078889	-0.101197083258205	0.91939401205649	0.953530877752372	744	D-glycero-alpha-D-manno-heptose 1-phosphate guanylyltransferase	Lipopolysaccharide synthesis	K15669	 Glycan biosynthesis and metabolism	              Glycan biosynthesis and metabolism	               00540 Lipopolysaccharide biosynthesis	COG1208	JM
LFTS_02316	286.091419783583	0.0182289880640485	0.182036268727649	0.100139319441454	0.920233719802381	0.954003764565771	1755	NADH-quinone oxidoreductase subunit L	NADH dehydrogenase	K05577	 Energy metabolism	              Energy metabolism	               00190 Oxidative phosphorylation	COG1009	CP
LFTS_00724	3701.21546584069	-0.0137937686535031	0.139097414918301	-0.0991662473497792	0.921006273440855	0.954406667684021	1668	general secretion pathway protein D	NA	K02453	 Cellular community - prokaryotes; Membrane transport	              Membrane transport	               03070 Bacterial secretion system	COG1450	U
LFTS_00006	287.674177120605	0.016796363404511	0.174307009161414	0.096360803190404	0.923234021733579	0.956316574179032	492	7-carboxy-7-deazaguanine synthase	NA	K10026	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00790 Folate biosynthesis	COG0602	R
LFTS_01230	127.043111926407	-0.0197729679656142	0.212361266058318	-0.0931100493636358	0.925816133883177	0.958342564364523	267	Acetyltransferase (GNAT) family protein	NA	K09994	 Metabolism of other amino acids	              Metabolism of other amino acids	               00440 Phosphonate and phosphinate metabolism	COG0454	KR
LFTS_00144	633.162873076154	0.0148791979354338	0.160115673744314	0.0929278039275164	0.925960916976502	0.958342564364523	1005	anthranilate phosphoribosyltransferase	NA	K00766	 Overview; Amino acid metabolism	              Overview	               01230 Biosynthesis of amino acids	COG0547	E
LFTS_00039	461.36883457517	0.0153906885303243	0.166776164806615	0.0922835019510765	0.926472795967012	0.958473312848103	669	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01162	3.54558681545697	-0.0367790225213737	0.404464005065398	-0.0909327457097867	0.927546030656152	0.959184455994673	876	nitrogenase iron protein NifH	Nitrogenase genes	K02588	 Energy metabolism; Xenobiotics biodegradation and metabolism	              Energy metabolism	               00910 Nitrogen metabolism	COG1348	P
LFTS_01759	113.459634996369	0.0224709453211913	0.250688287993357	0.0896369970095562	0.928575683369579	0.959713794305347	447	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01136	132.371727659949	-0.0212400812932691	0.23780564921	-0.0893169752856146	0.928830003659962	0.959713794305347	549	CRISPR-associated protein%2C Cse2 family	NA	NA	NA	NA	NA	NA	NA
LFTS_00607	970.586669341391	-0.0113344394879942	0.128636771524258	-0.0881119710459837	0.929787681868907	0.960304186591651	1173	cell division protein FtsZ	NA	K03531	 Cell growth and death	              Cell growth and death	               04112 Cell cycle - Caulobacter	COG0206	D
LFTS_01790	275.086540573125	-0.0160138020360798	0.182895640587459	-0.0875570461091557	0.930228743244664	0.960360737419533	132	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01902	779.767042334169	0.0115001195424673	0.136653035846187	0.0841556096522548	0.932932711299416	0.962752478327251	1551	GMP synthase (glutamine-hydrolysing)	NA	K01951	 Xenobiotics biodegradation and metabolism; Nucleotide metabolism	              Nucleotide metabolism	               00230 Purine metabolism	COG0518;COG0519	F
LFTS_01045	5.65064624856943	0.035253906737877	0.432295144791777	0.0815505498098013	0.935004125778639	0.964366593406469	156	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01131	168.500446529161	0.0161024854547827	0.198275060622149	0.0812128636060237	0.935272669631133	0.964366593406469	2340	type IV secretion system protein VirD4	NA	K03205	 Membrane transport	              Membrane transport	               03070 Bacterial secretion system	COG3505	U
LFTS_02386	1569.44018452312	-0.0141857370066239	0.177780213925163	-0.0797936772232446	0.936401353135591	0.964743926656935	1221	alanine racemase	NA	K01775	 Metabolism of other amino acids; Drug resistance	              Metabolism of other amino acids	               00473 D-Alanine metabolism	COG0787	M
LFTS_01460	409.868125357997	-0.01315825815268	0.164938364116314	-0.0797768198028254	0.93641476066902	0.964743926656935	2559	putative ABC transport system permease protein	NA	K02004	NA	              Folding, sorting and degradation	               04130 SNARE interactions in vesicular transport	COG0577;COG3127	VQ
LFTS_01038	35.2311064056149	-0.029551294156439	0.378476802583745	-0.0780795387054144	0.937764783245456	0.965734569655429	345	hypothetical protein	NA	K00149	 Amino acid metabolism; Metabolism of other amino acids; Carbohydrate metabolism; Lipid metabolism	              Carbohydrate metabolism	               00010 Glycolysis / Gluconeogenesis	NA	
LFTS_00164	655.554126260004	-0.0116144815871444	0.149827195965943	-0.0775191814294147	0.938210532612737	0.965793533778577	621	hypothetical protein	NA	K07285	NA	              Signal transduction	               02020 Two-component system	COG3065	M
LFTS_00311	6.46876840042103	-0.0331745113336563	0.433834973440155	-0.0764680428380275	0.939046737632383	0.966254217613454	339	nitrogen regulatory protein P-II family protein	Nitrate/nitrite regulation	K04751	 Signal transduction	              Signal transduction	               02020 Two-component system	COG0347	TE
LFTS_00038	189.07292145128	-0.0164989425429304	0.223837741785688	-0.0737093861442154	0.941241630045146	0.968111995156075	606	multiple antibiotic resistance protein	NA	K05595	NA	              Membrane transport	               02010 ABC transporters	COG2095	E
LFTS_00466	608.802784493906	-0.0109061623926769	0.14966152933747	-0.0728721832588299	0.941907829618794	0.968396552701539	1263	Fe-S oxidoreductase	NA	K00113	 Lipid metabolism	              Lipid metabolism	               00564 Glycerophospholipid metabolism	COG0247	C
LFTS_00318	501.908615348469	-0.0137432634365819	0.190925126293715	-0.071982476604151	0.942615853315032	0.96872385752012	453	thioredoxin	Oxidative stress response	K03672	NA	              Signal transduction	               02020 Two-component system	COG0526	O
LFTS_00684	464.481983931291	-0.0103827863609783	0.148500068116114	-0.069917721201716	0.944259148167167	0.969612947526843	342	divalent cation tolerance protein	Copper resistance	K03926	NA	              Folding, sorting and degradation	               03060 Protein export	COG1324	P
LFTS_01931	509.820902659962	-0.0104335520669537	0.149231219628103	-0.0699153440744841	0.944261040210171	0.969612947526843	1089	SAM-dependent methyltransferase%2C MidA family	NA	NA	NA	NA	NA	NA	NA
LFTS_00898	795.373659809563	-0.00990633415485307	0.143444246430655	-0.0690605193401192	0.944941446965954	0.969910998000562	837	protein TonB	NA	K03832	NA	              Metabolism of cofactors and vitamins	               00790 Folate biosynthesis	COG0810	M
LFTS_00867	2259.25067447786	-0.00943316747108567	0.138420009128786	-0.0681488719041267	0.945667126600532	0.970191325790287	2715	valyl-tRNA synthetase	NA	K01873	 Translation	              Translation	               00970 Aminoacyl-tRNA biosynthesis	COG0525	J
LFTS_00709	625.479669629717	0.00962027906008065	0.142024219212427	0.06773689102766	0.945995081945155	0.970191325790287	3108	PAS domain S-box-containing protein/diguanylate cyclase (GGDEF) domain-containing protein	Genes encoding proteins with EAL and GGDEF domains	K14051	 Cellular community - prokaryotes	              Cellular community - prokaryotes	               02024 Quorum sensing	COG2199;COG2200;COG2202	T
LFTS_01630	307.995770344887	0.0117544308359469	0.178393882227154	0.0658903247644988	0.947465143563712	0.971298287381191	1290	Major Facilitator Superfamily protein	NA	K08217	NA	              Carbohydrate metabolism	               00630 Glyoxylate and dicarboxylate metabolism	COG0477	GEPR
LFTS_01975	20.7674556736731	0.0238422930909563	0.375896553147446	0.0634278045151536	0.949425847020821	0.972907112816884	132	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_02216	41.3349481472642	0.0206795328289502	0.33515504470293	0.0617013921043018	0.950800631344806	0.973803956045703	225	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_02059	241.335510341115	0.0114795958664098	0.188061508413379	0.0610417089773438	0.951325992008263	0.973803956045703	2925	iron complex outermembrane recepter protein	NA	K02014	NA	              Cell growth and death	               04112 Cell cycle - Caulobacter	COG1629	P
LFTS_02086	51.1993754958581	-0.0189557204065538	0.313831137885377	-0.0604010186314817	0.951836247389916	0.973803956045703	1566	OmpA family protein	NA	K03640	NA	              Carbohydrate metabolism	               00520 Amino sugar and nucleotide sugar metabolism	COG2885	M
LFTS_02186	272.439026805162	0.0124768647981345	0.206780984259868	0.0603385501949949	0.951885999247671	0.973803956045703	954	squalene synthase HpnC	NA	K02291	 Metabolism of terpenoids and polyketides	              Metabolism of terpenoids and polyketides	               00906 Carotenoid biosynthesis	COG1562	I
LFTS_01602	682.233681507829	0.0147446824585667	0.246280620294706	0.0598694385328526	0.952259620734957	0.973803956045703	207	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_02262	548.883842083248	-0.00930884656011419	0.159701927315162	-0.0582888805201691	0.953518524516152	0.974690399649323	357	histidine triad (HIT) family protein	NA	K02503	NA	              Overview	               01230 Biosynthesis of amino acids	COG0537	FGR
LFTS_01111	52.6243029565268	0.018802634449576	0.341933041210637	0.0549892294204853	0.956147044487885	0.976975566213269	1005	hypothetical protein	NA	K02314	 Replication and repair; Cell growth and death	              Replication and repair	               03030 DNA replication	COG0305	L
LFTS_00439	262.499173783658	-0.0127818236296708	0.236306991297517	-0.0540899088913461	0.956863532017136	0.977305973950124	1605	cytochrome d ubiquinol oxidase subunit I	Cytochrome bd	K00425	 Energy metabolism; Signal transduction	              Energy metabolism	               00190 Oxidative phosphorylation	COG1271	C
LFTS_01721	763.135142834672	0.00985614326931349	0.189422593530944	0.052032564255348	0.958502746025463	0.97807587646844	552	EamA-like transporter family protein	Lipopolysaccharide synthesis	K12962	 Drug resistance	              Drug resistance	               01503 Cationic antimicrobial peptide (CAMP) resistance	COG0697	GER
LFTS_01849	2405.9065831279	0.00647914926957537	0.125170591932972	0.0517625519662389	0.958717894730254	0.97807587646844	1197	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00972	167.949631407547	0.010977839523063	0.213539054203815	0.0514090481668286	0.958999574914244	0.97807587646844	573	hypothetical protein	NA	K01317	NA	              Membrane transport	               03070 Bacterial secretion system	NA	
LFTS_00291	295.807054822008	-0.010292991176206	0.201157818071056	-0.0511687354481552	0.959191064694311	0.97807587646844	627	Holliday junction DNA helicase subunit RuvA	NA	K03550	 Replication and repair	              Replication and repair	               03440 Homologous recombination	COG0632	L
LFTS_00298	1754.29229335785	-0.00825420040643507	0.163087195521631	-0.0506121917176524	0.95963454769175	0.978126890349196	672	phosphoribosylformylglycinamidine synthase	NA	NA	NA	NA	NA	NA	NA
LFTS_00929	1022.39778195154	0.00646519118055698	0.131669899474925	0.0491015122388559	0.960838398270586	0.97895256479536	1788	arginyl-tRNA synthetase	NA	K01887	 Translation	              Translation	               00970 Aminoacyl-tRNA biosynthesis	COG0018	J
LFTS_00687	1824.10348887284	0.00593433373673511	0.122522783633994	0.0484345324251075	0.961369938693917	0.979092858497779	372	NADH dehydrogenase subunit A	NADH dehydrogenase	K00330	 Energy metabolism	              Energy metabolism	               00190 Oxidative phosphorylation	COG0838	C
LFTS_02136	140.665084124552	0.0117959672279482	0.255536203674594	0.0461616282089307	0.963181426106185	0.980536046396386	1563	Bacterial Ig-like domain (group 3)	NA	K01361	NA	              Translation	               03010 Ribosome	COG1404	O
LFTS_01184	10.1038948464951	0.0197049750132726	0.431588267017668	0.0456568830043425	0.963583730324125	0.980544066142356	327	nitrogen regulatory protein P-II family protein	Nitrate/nitrite regulation	K02589	NA	              Signal transduction	               02020 Two-component system	COG0347	TE
LFTS_01391	1041.73653676381	0.00698255641551312	0.156557105929516	0.0446006993681703	0.964425585200983	0.980999183637333	1386	dihydrolipoamide dehydrogenase	NA	K00382	 Carbohydrate metabolism; Amino acid metabolism; Overview	              Overview	               01200 Carbon metabolism	COG1249	C
LFTS_01223	48.4171311773958	0.0130412330558338	0.304494397624189	0.0428291395755972	0.965837735273407	0.981690227944464	240	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_02193	1032.89128321255	0.00589655056339649	0.137906353666728	0.0427576424625541	0.965894729506098	0.981690227944464	1611	hypothetical protein	NA	K11274	NA	              Carbohydrate metabolism	               00630 Glyoxylate and dicarboxylate metabolism	NA	
LFTS_02207	2632.70262295302	-0.00540965670210815	0.140900042626527	-0.0383935774700021	0.969373881644811	0.984618660333699	4875	putative helicase	NA	K01153	NA	              Glycan biosynthesis and metabolism	               00550 Peptidoglycan biosynthesis	COG0610	V
LFTS_01600	4111.99706531288	0.0137631577295194	0.360765334354515	0.0381498897452122	0.969568173973007	0.984618660333699	1053	hypothetical protein	NA	K06115	NA	              Cellular community - prokaryotes	               02024 Quorum sensing	NA	
LFTS_01982	1698.02511789643	-0.00585198693974322	0.164527924616066	-0.0355683508036652	0.971626544745517	0.985732843763696	798	proteasome beta subunit	NA	K03433	 Folding, sorting and degradation	              Folding, sorting and degradation	               03050 Proteasome	COG0638	O
LFTS_01542	794.271014853587	0.00594304905424622	0.170825035362488	0.0347902697144781	0.972246979579112	0.985732843763696	885	methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase	NA	K01491	 Metabolism of cofactors and vitamins; Energy metabolism; Overview	              Overview	               01200 Carbon metabolism	COG0190	H
LFTS_01601	2470.96711615578	0.0128104137140406	0.368627883803968	0.0347516134206849	0.972277804199706	0.985732843763696	855	hypothetical protein	NA	K07114	NA	              Cellular community - prokaryotes	               02024 Quorum sensing	COG2304	R
LFTS_02019	291.930548143388	0.00620502148916761	0.180521400386454	0.0343727750609298	0.972579892992926	0.985732843763696	723	Helix-turn-helix domain protein	NA	NA	NA	NA	NA	NA	NA
LFTS_02001	219.990626249421	0.00667011565365542	0.194534921712656	0.0342874975605033	0.972647894510196	0.985732843763696	708	YbbR-like protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00883	855.813362749718	0.00469618886754241	0.159286758236081	0.0294826068378021	0.976479690644561	0.989212922144408	564	putative arylsulfatase	NA	K07177	 Cellular community - prokaryotes	              Cellular community - prokaryotes	               02024 Quorum sensing	COG3480	T
LFTS_02247	604.983707688926	-0.00451024819596437	0.157835936961459	-0.028575546753118	0.977203114982586	0.989252903039249	897	Oligoribonuclease NrnB or cAMP/cGMP phosphodiesterase%2C DHH superfamily	NA	K07097	NA	              Carbohydrate metabolism	               00520 Amino sugar and nucleotide sugar metabolism	COG2404	JT
LFTS_01853	145.036504278154	-0.00593992072687908	0.20889291547325	-0.0284352425903104	0.977315016035557	0.989252903039249	774	Threonine/homoserine efflux transporter RhtA	NA	K15269	NA	              Folding, sorting and degradation	               03060 Protein export	COG0697	GER
LFTS_01896	288.181158967251	0.00503006607442599	0.18022942273505	0.0279092392246106	0.977734539479439	0.989274751789127	480	Acetyltransferase (GNAT) family protein	NA	K03789	NA	              Replication and repair	               03030 DNA replication	COG0456	J
LFTS_01058	14.0219845812416	-0.0113747229268353	0.415045890922651	-0.0274059403444501	0.978135960319904	0.989278273944378	261	hypothetical protein	NA	K07319	NA	              Energy metabolism	               00190 Oxidative phosphorylation	COG0863	L
LFTS_00566	154.056651054177	-0.00556128862014383	0.218475640529373	-0.0254549596772833	0.979692073804941	0.990446833885577	1026	UDP-glucuronate 4-epimerase	Extracellular polysaccharide production and export	K08679	 Carbohydrate metabolism	              Carbohydrate metabolism	               00520 Amino sugar and nucleotide sugar metabolism	COG0451	M
LFTS_00866	927.730725817776	0.00325886975300069	0.130572279054655	0.0249583585167919	0.980088178342123	0.990446833885577	1026	hypothetical protein	NA	K07082	NA	              Translation	               00970 Aminoacyl-tRNA biosynthesis	COG1559	D
LFTS_02281	232.417166987657	-0.00452557236601308	0.189951005711477	-0.0238249455382569	0.980992242032766	0.990957624418309	159	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00295	388.973510445872	0.00402154419478173	0.173447026029648	0.023186008355625	0.981501899323271	0.991069748869883	1641	HAMP domain-containing protein	NA	K02482	NA	              Signal transduction	               02020 Two-component system	COG0642	T
LFTS_01862	534.193062873532	-0.00416956393823695	0.187654240422328	-0.0222193963155487	0.982272945387254	0.991142325066213	636	undecaprenyl-diphosphatase	NA	K01096	 Lipid metabolism	              Lipid metabolism	               00564 Glycerophospholipid metabolism	COG0671	I
LFTS_02023	62.2626642116891	0.00647223478273791	0.292910609538781	0.0220962797931052	0.982371154047928	0.991142325066213	804	plasmid and phage iteron-binding protein	NA	NA	NA	NA	NA	NA	NA
LFTS_02525	1084.2651081145	-0.00340382537574167	0.159359895742234	-0.0213593599562049	0.982958992220005	0.991333085054334	1689	hopanoid C-3 methylase HpnR	NA	K04034	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00860 Porphyrin and chlorophyll metabolism	COG1032	R
LFTS_02033	3.76014078427021	0.00830895692718889	0.41271796613322	0.0201322879278458	0.983937843318886	0.991917874489355	195	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00784	8575.01908620308	-0.00287858501937258	0.152967532837806	-0.0188182744793615	0.984986075477675	0.992572105244224	1389	hydroxymethylpyrimidine synthase	NA	K03147	 Metabolism of cofactors and vitamins	              Metabolism of cofactors and vitamins	               00730 Thiamine metabolism	COG0422	H
LFTS_02486	1655.52683538208	-0.0026491861423304	0.147212215567548	-0.0179956950727015	0.985642287690413	0.99283092674164	1563	phosphoenolpyruvate carboxylase	Reductive TCA cycle carbon dioxide fixation	K01595	 Energy metabolism; Overview; Carbohydrate metabolism	              Overview	               01200 Carbon metabolism	COG2352;COG1892	CG
LFTS_02521	202.925800185112	0.00333183505409005	0.1938863031536	0.0171844787377812	0.986289444535256	0.993080420864579	966	Permease of the drug/metabolite transporter (DMT) superfamily protein	NA	K03298	NA	              Metabolism of cofactors and vitamins	               00860 Porphyrin and chlorophyll metabolism	COG0697	GER
LFTS_02246	430.921096009443	-0.00240832103981824	0.154527647504669	-0.0155850495280818	0.987565432984041	0.993962617975031	738	ribonuclease PH	NA	K00989	NA	              Carbohydrate metabolism	               00520 Amino sugar and nucleotide sugar metabolism	COG0689	J
LFTS_02223	2.62482814475908	0.00535258775571444	0.382656483927973	0.0139879708838854	0.988839577943531	0.99484224636488	1035	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00383	25.8129230709039	0.00473108052332836	0.377412060395299	0.012535583834743	0.98999831314391	0.995605099707023	924	putative DNA primase/helicase	NA	K02316	 Replication and repair	              Replication and repair	               03030 DNA replication	COG0358	L
LFTS_00637	39.3327195273802	-0.00365669006024042	0.316050626816042	-0.0115699503496596	0.990768721202812	0.99597696761431	261	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01050	5.48460273836964	0.00448457312684192	0.43040004279781	0.0104195461917011	0.991686555390886	0.996496676112264	138	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_01851	67.2031557083593	-0.00285985368924485	0.299581446202372	-0.00954616424180346	0.992383378619587	0.996793971413452	1542	MFS transporter%2C DHA2 family%2C multidrug resistance protein	NA	K03446	NA	              Folding, sorting and degradation	               03060 Protein export	COG0477	GEPR
LFTS_00310	19.5863210121424	0.00306230781637975	0.401510809653457	0.0076269623201996	0.993914623517232	0.997921158102586	1473	ammonium transporter%2C Amt family	Ammonia & glutamate conversion to glutamine	K03320	NA	              Signal transduction	               02020 Two-component system	COG0004	P
LFTS_01116	31.9497010670924	0.00244603658809776	0.342898638991206	0.00713341002254748	0.994308410547106	0.997921158102586	525	hypothetical protein	NA	K12080	NA	              Signal transduction	               02020 Two-component system	COG3451	U
LFTS_00718	192.389964650046	-0.00138785948468641	0.225042090769733	-0.00616711069444558	0.995079388783302	0.998214417124277	591	Type II secretion system (T2SS)%2C protein M	NA	K02462	 Cellular community - prokaryotes; Membrane transport	              Membrane transport	               03070 Bacterial secretion system	COG3149	U
LFTS_00639	65.0423630573022	-0.00153676956048967	0.26676928925515	-0.00576066894649118	0.995403676609446	0.998214417124277	987	AAA domain-containing protein	NA	K07505	NA	              Replication and repair	               03030 DNA replication	COG3598	L
LFTS_00632	436.767441372042	0.00104294699962978	0.199807773535729	0.00521975187038099	0.995835259483364	0.998244538336953	588	Terminase small subunit	NA	K07474	NA	              Replication and repair	               03030 DNA replication	COG3728	X
LFTS_01272	440.985456915031	0.000745225706939549	0.186810885410138	0.00398919851647524	0.996817088535714	0.998825990366701	333	hypothetical protein	NA	NA	NA	NA	NA	NA	NA
LFTS_00165	887.892171304743	0.000438904766256904	0.157326887379088	0.00278976323480765	0.997774093873941	0.999045884524331	1377	Outer membrane protein TolC	NA	K15725	NA	              Signal transduction	               02020 Two-component system	COG1538	M
LFTS_00405	1857.05496155853	-0.000255147373056583	0.118412300344596	-0.00215473706966311	0.998280769889893	0.999045884524331	2655	PAS domain S-box-containing protein/diguanylate cyclase (GGDEF) domain-containing protein	Genes encoding proteins with EAL and GGDEF domains	K14051	 Cellular community - prokaryotes	              Cellular community - prokaryotes	               02024 Quorum sensing	COG2199;COG2200;COG2202	T
LFTS_00315	214.900354396976	-0.000372004004127716	0.209802214894124	-0.00177311762087663	0.998585257567127	0.999045884524331	762	Ni/Fe-hydrogenase 1 B-type cytochrome subunit	NA	K03620	 Signal transduction	              Signal transduction	               02020 Two-component system	COG1969	C
LFTS_00562	188.350618305643	0.000333128989460486	0.196018752212361	0.00169947510480826	0.998644015705134	0.999045884524331	1116	diguanylate cyclase (GGDEF) domain-containing protein	Putative diguanylate cyclases (GGDEF domain-containing proteins)	K13590	 Cell growth and death	              Cell growth and death	               04112 Cell cycle - Caulobacter	COG2199	T
LFTS_02439	1243.88154679138	-0.000118434990710674	0.16601683680692	-0.0007133914426307	0.999430796030397	0.999430796030397	537	regulatory protein%2C Fis family	NA	K03557	 Cellular community - prokaryotes	              Cellular community - prokaryotes	               05111 Biofilm formation - Vibrio cholerae	COG2901	K