Investigations

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These investigations reveal that Synechocystis has neither an ED pathway nor a glucose dehydrogenase/glucokinase (GHD/GK) bypass. It rather contains a promiscuous aldolase EDA that prefers KDPG as substrate but also decarboxylates oxaloacetate (OAA) and cleaves 2-keto-4-hydroxyglutarate (KHG). In addition, the synthesis of KDPG from pyruvate and GAP is catalyzed with very low efficiency.

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