Kinetics Minireviews

Minireviews about each enzyme in the mitochindrial beta-oxidation model on which the final parameter choices (fixed-parameter model) and parameter sampling distributions (ensemble) were based.

DOI: 10.15490/fairdomhub.1.assay.2137.1

Zenodo URL: None

Created at: 3rd Mar 2024 at 08:13

Contents

Parameter Search SOP

No description specified

  • Parameter search SOP.pdf

CPT1

Carnitine palmitoyltransferase 1 (EC 2.3.1.21)

  • 1, CPT1.pdf

Equilibrium constants

The theory, calculations, and conditions that went into estimating the Keqs.

  • 0, Theory - Estimating the equilibrium constants.pdf

CACT

Carnitine acylcarnitine translocase (UniProt: O43772)

  • 2, CACT.pdf

CPT2

Carnitine palmitoyltransferase 2 (EC 2.3.1.21)

  • 3, CPT2.pdf

CrAT

Carnitine acetyltransferase (EC 2.3.1.7)

  • 4, CrAT.pdf

SCAD

Short-chain acyl-CoA dehydrogenase (EC 1.3.99.2)

  • 5, SCAD.pdf

MCAD

Medium-chain acyl-CoA dehydrogenase (EC 1.3.99.3)

  • 6, MCAD.pdf

VLCAD

Very long-chain acyl-CoA dehydrogenase (EC 1.3.8.9)

  • 7, VLCAD.pdf

CROT

Crotonase / Enoyl-CoA hydratase (EC 4.2.1.17)

  • 8, CROT.pdf

MSCHAD

Medium-/short-chain hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35)

  • 9, MSCHAD.pdf

MCKAT

Medium-chain ketoacyl-CoA thiolase (EC 2.3.1.16)

  • 10, MCKAT.pdf

MTP

Mitochondrial trifunctional protein (UniProt: P40939)

  • 11, MTP.pdf

ACOT

Acyl-CoA thioesterases (EC 3.1.2.1. and EC 3.1.2.2)

  • 12, ACOT.pdf

Carnitine

L-carnitine as conserved moiety

  • 13.1, CarMAT and CarCYT.pdf

CoA

CoA as conserved moiety

  • 13.2, CoAMAT and CoACYT.pdf

Acetyl-CoA (mito)

Acetyl-CoA in the mitochondrion as constant metabolite

  • 13.3, AcetylCoAMAT.pdf

NADH and NAD+

NADH and NAD+ (Nicotinamide adinine dinucleotide) as constant values.

  • 13.4, NAD and NADH.pdf

ETF

Oxidised and reduced electron transferring flavoprotein as constant values.

  • 13.5, ETF.pdf

Compartment volumes

Volume per mg mitochondrial protein of mitochondrion and cytosol.

  • 13.6, Compartment Volumes.pdf
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Citation
Odendaal, C., Bakker, B., Kiyuna, L. A., Van Eunen, K., Jager, E., & Abegaz, F. (2024). Kinetics Minireviews. FAIRDOMHub. https://doi.org/10.15490/FAIRDOMHUB.1.ASSAY.2137.1
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Created: 3rd Mar 2024 at 08:13

Last updated: 3rd Mar 2024 at 08:13

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