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Arnau Montagud1
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COVID-19 Disease Map1
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Disease Maps1
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Investigation visible to you, out of a total of 1
Multiscale and multicellular simulation of SARS-CoV-2 infection uncover points of intervention to evade apoptosis.
Summary:
Our framework enables the simulation of the dynamics of signaling pathways that include the relevant players in SARS-CoV-2 infection, at the level of the individual cell and of the cell population. These different players encompass the virus, epithelial and immune cells. The model focuses on apoptosis and suggests two knock out alterations that force apoptosis of the ...
