Alignments of various alpha-tubulin and beta-tubulin sequences from dinitroaniline-sensitive and dinitroaniline-resistant species. Sequences were retrieved from UniProt with the identifiers listed below and subjected to a multiple sequence alignment using ClustalOmega (ebi.ac.uk/Tools/msa/clustalo/; ClustalOmega webserver, last accessed 16-02-23):
alpha-tubulin:
- [dinitroaniline sensitive] T. cruzi - Q27352; T. brucei brucei - Q4GYY5; L. infantum - ...
Submitter: Ina Poehner
Biological problem addressed: Model Analysis Type
Investigation: Antiparasitic dinitroaniline-ether phospholipid...
Clustal Omega multiple sequence alignment result for selected beta-tubulins in FASTA format with gaps. Species and corresponding Uniprot identifiers can be found in the FASTA file.
The following species (Uniprot ID, dinitroaniline-sensitive/resistant) were considered:
- Trypanosoma cruzi (Q8STF3, sensitive)
- Trypanosoma brucei brucei (Q4GYY6, sensitive)
- Leishmania infantum (A4HZJ3, sensitive)
- Leishmania donovani (I3W8N7, sensitive)
- Leishmania major (Q4QBZ6, sensitive)
- Toxoplasma gondii ...
Creators: Ina Poehner, Rebecca Wade
Submitter: Ina Poehner
DownloadClustal Omega multiple sequence alignment result for selected alpha-tubulins in FASTA format with gaps. Species and corresponding Uniprot identifiers can be found in the FASTA file.
The following species (Uniprot ID, dinitroaniline-sensitive/resistant) were considered:
- Trypanosoma cruzi (Q27352, sensitive)
- Trypanosoma brucei brucei (Q4GYY5, sensitive)
- Leishmania infantum (E9AGJ8, sensitive)
- Leishmania donovani (I3W8N6, sensitive)
- Leishmania major (Q4QGC5, sensitive)
- Toxoplasma gondii ...
Creators: Ina Poehner, Rebecca Wade
Submitter: Ina Poehner
