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The aim of the exposure was to study the effects of activation of peroxisome proliferator-activated receptors (PPARs) in Atlantic cod (Gadus morhua), by injecting the fish with the compounds WY-14,643 and GW501516. Using luciferase reporter assay in vitro, we have shown that WY-14,643 activate Atlantic cod Ppara1 and Ppara2, while GW501516 activate Ppara1, Ppara2, and Pparb. The experimental set-up was as follows: Immature cod were injected at day 0 and day 4 with either high dose (40 mg/kg ...

Creators: None

Submitter: Marta Eide

Untargeted lipidomics analysis was performed on plasma and liver samples of four male fish from each group (n = 4) at Per Bruheim’s lab at NTNU, Norway, using Liquid Chromatography Hybrid Quadrupole Mass Spectrometry (UPLC-HDMS).

Normalisation: The fraction of each lipid compound among all measured lipids in every sample was calculated and was used in the downstream analysis.

Creators: None

Submitter: Marta Eide

No description specified

Creators: None

Submitter: Marta Eide

No description specified

Creators: None

Submitter: Marta Eide

No description specified

Creators: None

Submitter: Marta Eide

Biometric data from in vivo II experiment

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