Investigations

Patients subjected to extended liver resection ((e)PHx) have a high risk to experience postoperative liver dysfunction or even liver failure, especially in case of preexisting liver disease. Our research group QuaLiPerF aims to enhance the understanding of the quantitative and spatial relationship between hepatic perfusion and function in healthy, steatotic and regenerating livers after surgery using a systems medicine approach. This project will focus on assessing the impact of perfusion ...

Within the overarching goal of the research unit QuaLiPerF to gain a data-integrated, multi-scale understanding of the interplay between hepatic perfusion and function and its recovery after extended hepatectomy (ePHx), this subproject (P6) is devoted to experimental MRI investigations in rats. This subproject aims to establish a comprehensive MR imaging toolbox for small animal imaging at 9.4T and to provide MRI-based spatially resolved, multi-parametric quantitative in vivo information on liver ...