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Abstract (Expand)

Systems Biology has a mission that puts it at odds with traditional paradigms of physics and molecular biology, such as the simplicity requested by Occam's razor and minimum energy/maximal efficiency. … By referring to biochemical experiments on control and regulation, and on flux balancing in yeast, we show that these paradigms are inapt. Systems Biology does not quite converge with biology either: Although it certainly requires accurate 'stamp collecting', it discovers quantitative laws. Systems Biology is a science of its own, discovering own fundamental principles, some of which we identify here.

Authors: , Catherine Winder, , Evangelos Simeonidis, Malgorzata Adamczyk, , Frank J Bruggeman, Warwick Dunn

Date Published: 6th Nov 2009

Publication Type: Not specified

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