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The Lactate dehydrogenases (LDH) are key metabolic enzymes in lactic acid bacteria (LAB). The LDH ( E.C. 1.1.1.27) catalyzes the reaction of pyruvate and NADH into lactate and NAD+.We have carried out an experimental and computational study of the effects of fructose-1,6-bisphosphate (FBP), phosphate (Pi) and ionic strength (NaCl concentration) on 3 LDHs from 3 LABs studied at pH 6 and pH 7.
Submitter: Silvio Hering
Investigation: Investigation of glycolysis and pyruvate branch...
Assays: Kinetics of L-lactate dehydrogenase from S. pyogenes, E. faecalis, and L...
