Data files

Absorption at 340 nm measured over time in assays performed to determine the IC50 of fruc-1,6-BP for various PGMs as well as calculations perfomed to determine the specific activity [%] normalized to the activity in absence of fruc-1,6-BP

AUC of measured EIC of glc-1,6-BP for each reaction supernatant measured for fig 6b as well as the calculated normalized AUC (normalized to the control).

Data depicted in fig S1

Raw data of absorption at 340 nm during the enzyme assays performed for fig 5 as well as calculations to generate specific activities (inpresence and absence of 100 µM fruc-1,6-BP) from raw data.

Data depicted in fig S2

Raw data of absorption at 340 nm during the enzyme assays performed for fig 2 and 3 as well as calculations to generate specific activities from raw data.

Raw data of absorption at 340 nm during the enzyme assays performed for fig 4 as well as calculations to generate specific activities from raw data.

Raw data of absorption at 340 nm during the enzyme assays performed for fig 5 as well as calculations to generate specific activities and fold changes from raw data.

Raw data of absorption at 340 nm during the enzyme assays performed for fig 6b as well as calculations to generate specific activities and fold changes from raw data.

phylogenetic tree data depicted in fig 1a

phylogenetic tree data depicted in fig 1b

Specific activites of PGM enzymes with and without 40 µM glc-1,6-BP/ 100 µM fruc-1,6-BP.

Specific activites of PGM enzymes with and without 40 µM glc-1,6-BP/ 100 µM fruc-1,6-BP.

Proteinsequences used to generate the phylogenetic trees of fig 1

Michaelis-Menten kinetic of SynPGM1 in absence and presence of the effectors glucose-1,6-bisphosphate and fructose-1,6-bisphosphate.