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MS Proteomics raw data H80 vs Miltefosine on L. infantum parasites

Giulia Malpezzi PhD raw data

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L. infantum promastigotes were administered with EC10 and EC50 concentrations of H80 and Miltefosine. Cells were fractionated into soluble (cyto), insoluble (membranes), and mitochondiral lysates, and analysed through LC-MS/MS Proteomics.

Creators: Giulia Malpezzi, Lorenzo Tagliazucchi, Maria Paola Costi

Submitter: Giulia Malpezzi

DOI: 10.15490/fairdomhub.1.datafile.8048.1

Investigations: No Investigations

Studies: No Studies

Assays: No Assays

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Created: 28th Oct 2025 at 10:18, Last updated: 28th Oct 2025 at 10:37

SUPPLEMENTARY INFORMATION to Pyrazolo piperidinone derivatives downregulate TEAD transcription and modulate the down-stream effectors of the Hippo Pathway to halt colorectal cancer cell growth

Mass spectrometry proteomics for biomarker discovery

No description specified

Creator: Lorenzo Tagliazucchi

Submitter: Lorenzo Tagliazucchi

Investigations: No Investigations

Studies: No Studies

Assays: No Assays

Created: 23rd Jul 2024 at 10:00

rawData_figure 5_Enhanced Anticancer Effect of Thymidylate Synthase Dimer Disrupters Promoting Intracellular Accumulation

Enhanced Anticancer Effect of Thymidylate Synthase Dimer Disrupters Promoting Intracellular Accumulation

Raw data of Figure 5, main text

Creator: Lorenzo Tagliazucchi

Submitter: Lorenzo Tagliazucchi

DOI: 10.15490/fairdomhub.1.datafile.7127.1

Investigations: No Investigations

Studies: No Studies

Assays: No Assays

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Created: 19th Feb 2024 at 10:14

RawData_figure4_Enhanced Anticancer Effect of Thymidylate Synthase Dimer Disrupters Promoting Intracellular Accumulation

Enhanced Anticancer Effect of Thymidylate Synthase Dimer Disrupters Promoting Intracellular Accumulation

Raw data of Figure 4, main text

Creator: Lorenzo Tagliazucchi

Submitter: Lorenzo Tagliazucchi

DOI: 10.15490/fairdomhub.1.datafile.7126.1

Investigations: No Investigations

Studies: No Studies

Assays: No Assays

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Created: 19th Feb 2024 at 10:12

RawData_figure3_Enhanced Anticancer Effect of Thymidylate Synthase Dimer Disrupters Promoting Intracellular Accumulation

Enhanced Anticancer Effect of Thymidylate Synthase Dimer Disrupters Promoting Intracellular Accumulation

Raw data of Figure 3, main text

Creator: Lorenzo Tagliazucchi

Submitter: Lorenzo Tagliazucchi

DOI: 10.15490/fairdomhub.1.datafile.7125.1

Investigations: No Investigations

Studies: No Studies

Assays: No Assays

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Created: 19th Feb 2024 at 10:08, Last updated: 19th Feb 2024 at 10:08

Datasheet_figure 2_ from Enhanced Anticancer Effect of Thymidylate Synthase Dimer Disrupters Promoting Intracellular Accumulation

Enhanced Anticancer Effect of Thymidylate Synthase Dimer Disrupters Promoting Intracellular Accumulation

raw data of Figure 2

Creator: Lorenzo Tagliazucchi

Submitter: Lorenzo Tagliazucchi

DOI: 10.15490/fairdomhub.1.datafile.7124.1

Investigations: No Investigations

Studies: No Studies

Assays: No Assays

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Created: 19th Feb 2024 at 10:02, Last updated: 19th Feb 2024 at 10:04

LFQ differential analysis of Sb(III), Paromomycin and Miltefosine resistant L infantum strains infecting THP-1 human monocytes vs non-resistant (ctrl) samples

MS identification of L infantum proteins related to their drug resistance patterns for new drug targets identification and ecotoxicological evaluations of their environmental and interspecies impact

No description specified

Creator: Lorenzo Tagliazucchi

Submitter: Lorenzo Tagliazucchi

Investigations: No Investigations

Studies: No Studies

Assays: No Assays

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Created: 20th Oct 2023 at 13:25, Last updated: 20th Oct 2023 at 13:29

LFQ differential analysis of Sb(III), Paromomycin and Miltefosine resistant L infantum strains infecting THP-1 human monocytes vs non-resistant (ctrl) samples

MS identification of L infantum proteins related to their drug resistance patterns for new drug targets identification and ecotoxicological evaluations of their environmental and interspecies impact

No description specified

Creator: Lorenzo Tagliazucchi

Submitter: Lorenzo Tagliazucchi

Investigations: No Investigations

Studies: No Studies

Assays: No Assays

Created: 20th Oct 2023 at 13:25

Supplementary Information 2 associated with the manuscript entitled " Label free Mass spectrometry proteomics reveals different pathways modulated in THP-1 cells infected with therapeutic failure and drug resistance Leishmania infantum clinical isolates"

No description specified

Creator: Lorenzo Tagliazucchi

Submitter: Lorenzo Tagliazucchi

Investigations: No Investigations

Studies: No Studies

Assays: No Assays

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Created: 3rd Jan 2023 at 02:19

No description specified

Creator: Lorenzo Tagliazucchi

Submitter: Lorenzo Tagliazucchi

Investigations: No Investigations

Studies: No Studies

Assays: No Assays

Created: 3rd Jan 2023 at 02:19

No description specified

Creator: Lorenzo Tagliazucchi

Submitter: Lorenzo Tagliazucchi

Investigations: No Investigations

Studies: No Studies

Assays: No Assays

Created: 3rd Jan 2023 at 02:18

Label free Mass spectrometry proteomics reveals different pathways modulated in THP-1 cells infected with therapeutic failure and drug resistance Leishmania infantum clinical isolates

No description specified

Creators: None

Submitter: Lorenzo Tagliazucchi

Investigations: No Investigations

Studies: No Studies

Assays: No Assays

Created: 17th Nov 2022 at 11:21

Label free Mass spectrometry proteomics reveals different pathways modulated in THP-1 cells infected with therapeutic failure and drug resistance Leishmania infantum clinical isolates

No description specified

Creators: None

Submitter: Lorenzo Tagliazucchi

Investigations: No Investigations

Studies: No Studies

Assays: No Assays

Created: 17th Nov 2022 at 11:21

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