Documents

This file contains Violin plots for mitochondrial gene transcripts (%mtRNA), cardiac marker (Tnnt2), and pace-maker marker (Hcn4) for identified cell clusters in iSABS and sinoatrial node region (results obtained from a data reanalysis of Goodyer et al.).

This file contains several Scatter plots illustrating the correlation of %mtDNA and (a) Tnnt2 (b) Hcn4 (c) total number of gene transcripts per cell In Tnnt2 positive cells and (d) total number of gene transcripts per cell In Hcn4 positive cells.

Graphical abstract for the manuscript "Quality control in scRNA-Seq can discriminate pacemaker cells – the mtDNA bias" by Anne-Marie Galow#, Sophie Kussauer, Markus Wolfien, Robert David*, and Andreas Hoeflich#*

This file contains a UMAP plot generated for the Goodyer dataset illustrating the various cell populations and their proportions as well as the original t-SNE plot of the respective data published by Goodyer et al. in 2019 (doi: 10.1161/CIRCRESAHA.118.314578).

This file contains a UMAP plot for the iSABs dataset illustrating the various cell populations and their proportions.

This file contains a detailed description of the underlying experimental procedure and the computational analysis.