Glucose metabolism in Plasmodium falciparum infected erythrocytes
DownloadThe investigation entails the construction and validation of a detailed mathematical model for glycolysis erythrocytes infected with the malaria parasite Plasmodium falciparum in the blood stage form.
DOI: 10.15490/fairdomhub.1.investigation.604.1
Zenodo URL: None
Created at: 18th Aug 2023 at 09:14
Validation of model for malaria-infected erythrocytes
This study includes the experimental data for model validation and the model predictions of that data set.
Steady-state
No description specified
Flux vs parasitaemia
No description specified
Flux vs external glucose
No description specified
Stage specific fluxes
No description specified
Analysis of model for malaria-infected erythrocytes
This study includes the experimental data for model validation and the model predictions of that data set.
Inhibition of glycolytic flux
Inhibition of lactate flux glycolytic inhibitors
Glycolytic flux inhibition data (erythrocytes)
No description specified
- Validation-GlycFluxInhibition-dutoit1.xlsx
Inhibition of glycolytic flux by glucose transport inhibitor (iRBC)
No description specified
- CytInh-dutoit1.nb
Validation of lactate flux inhibition by glucose transport inhibitor
No description specified
- LACfluxValidation_Inhibition-SEEK.nb
Glycolytic target analysis in malaria infected erythrocytes
No description specified
- TargetAnalysis-dutoit1.nb
Metabolic control analysis
No description specified
Intra-erythrocytic malaria parasite volumes
No description specified
Malaria parasite volume determinations
Determinations of parasite volumes in a well-synchronised, infected culture treated with a cytosolic stain, using fluorescence microscopy. Diameters used to calculate parasite volume, assuming a spherical parasite cell.
Malaria parasite volumes determined using microscopy
Volumes in fL, time in hours.
- ParasiteVolumes.csv
Analysis of malaria parasite volumes per stage
No description specified
- parasiteVolumeDetermination.nb
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Created: 18th Aug 2023 at 09:14
Last updated: 18th Aug 2023 at 09:15
