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Molecular Systems Biology1
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Jacky Snoep1
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Jacky Snoep1
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C A mutated stem cell with a strong inactivation of the sensing of y has a growth advantage (differentiates less), and therefore, it invades the stem- cell population. As a result, both the stem-cell pool and the number of terminally differentiated cells increase.
SED-ML simulation https://jjj.bio.vu.nl/models/experiments/karin2017_fig4c/simulate
Submitter: Jacky Snoep
Investigation: Karin et al (2017) Molecular Systems Biology
Assays: Biphasic control can provide mutant resistance to stem-cell homeostatic ...
