Studies
What is a Study?Filters
Query
Created At
Updated At
Project
Molecular Systems Biology1
Submitter
Jacky Snoep1
Creator
Jacky Snoep1
1
Study visible to you, out of a total of 1
Mathematical simulation of a tamoxifen-induced conditional knock-in of a sixfold activating GCK mutant in beta cells. (C) The percentage of beta cells with mutated GCK increases to ~25% after 3 days, but then decreases and is eliminated after a few weeks. (D) Glucose levels initially decrease after the tamoxifen injection, but return to normal after a few weeks. Insets: Experimental results of Tornovsky-Babeay et al (2014).
SED-ML simulation https://jjj.bio.vu.nl/models/experiments/karin2017_fig2/simulate ...
Submitter: Jacky Snoep
Investigation: Karin et al (2017) Molecular Systems Biology
Assays: Frequency-dependent selection of mutant pancreatic beta cells.
