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Mathematica notebook for simulation of HSD11B1 inhibition in human adipose tissue.

Steroid biosynthesis

HSD11B1 inhibition by AZD4017 and the effect on cortisone and 11KA4 metabolism was simulated in Mathematica. Figure 6 of the manuscript is reproduced in the notebook.

Creator: Jacky Snoep

Submitter: Jacky Snoep

Model type: Ordinary differential equations (ODE)

Model format: Mathematica

Environment: Mathematica

Organism: Not specified

Investigations: Effect of 11BHSD inhibition on 11-ketotestoster...

Studies: Inhibition of HSD11B1 in adipose tissue

Assays: Simulation of HSD11B1 inhibition in human adipo...

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Created: 24th Feb 2024 at 14:45

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