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A Mathematical Model of Metabolism and Regulation Provides a Systems-Level View of the Oxygen Response of Escherichia coli

SUMO

The model describes the catabolism of Escherichia coli and its regulation. The metabolic reactions are modeled by the thermokinetic model formalism. The model is simplified by assuming rapid equilibrium of many reactions. Regulation is modeled by phenomenological laws describing the activation or repression of enzymes and genes in dependence of metabolic signals. The model is intended to describe the behavior of E. coli in a chemostat culture in depedence on the oxygen supply.

The model is described ...

Creators: Michael Ederer, David Knies

Submitter: Michael Ederer

Model type: Ordinary differential equations (ODE)

Model format: Mathematica

Environment: Not specified

Organism: Escherichia coli

Investigations: Steady state studies for different oxygen avail...

Studies: The Escherichia coli steady state response to o...

Assays: Steady State Oxygen Response of E. coli WT and ...

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Created: 26th Oct 2009 at 14:48, Last updated: 18th Mar 2014 at 12:34

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