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Excel spreadsheet with 72h time points for metabolism of cortisone or 11KA4 in human subcutaneous or omental adipose tissue in presence or absence of AZD4017 inhibitor.

Transcriptome sequences merged from de novo assembly and IsoSeq sequence data.

Table with InterPro annotations, matches to Pcitri.v1 genome and differential expression between mated and virgin P.citri females for the transcripts in the consolidated P. citri transcriptome.

HSD11B1 was inhibited by CBX and the effect on the conversion of cortisone and 11KA4 in HSD11B1/AKR1C3 incubations was followed.

Raw data of Figure 5, main text

Raw data of Figure 4, main text

Raw data of Figure 3, main text

raw data of Figure 2

Metabolite profiles after 24h incubation with different ratios of HSD11B1 and AKR1C3 transfected HEK293 cells.

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  1. Genome of P. vulgatus ATCC 8482
  2. Identified proteins with peptide counts
  3. BioCyc-predicted biosynthesis of amino acids including identified proteins
  4. BioCyc-predicted biosynthesis of nucleotides including identified proteins
  5. BioCyc-predicted biosynthesis of fatty acids and cell wall including identified proteins
  6. Metabolites of the intracellular metabolome
  7. CoAs of the metabolome
  8. Metabolites of the extracellular metabolome

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