Principal Cell_Parametric ODE Equations

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R200	AKT1_p + RPS6KA3	AKT1_p \|RPS6KA3	AKT1_p + RPS6KA3 → AKT1_p \|RPS6KA3	V(200) = K(200,1) * [AKT1_p] * [RPS6KA3] -K(200,2) * [AKT1_p \|RPS6KA3];
R201	AKT1_p \|RPS6KA3	AKT1_p + RPS6KA3_p	AKT1_p \|RPS6KA3 → AKT1_p + RPS6KA3_p	V(201) = K(201,1) * [AKT1_p \|RPS6KA3];
R202	RPS6KA3 + RPS6KA3_p	RPS6KA3_p \|RPS6KA3	RPS6KA3 + RPS6KA3_p → RPS6KA3_p \|RPS6KA3	V(202) = K(202,1) * [RPS6KA3_p] * [RPS6KA3] -K(202,2) * [RPS6KA3_p \|RPS6KA3];
R203	RPS6KA3_p \|RPS6KA3	RPS6KA3_p + RPS6KA3_p	RPS6KA3_p \|RPS6KA3 → RPS6KA3_p + RPS6KA3_p	V(203) = K(203,1) * [RPS6KA3_p \|RPS6KA3];
R204	EP300 + PRKAA1	PRKAA1 \|EP300	EP300 + PRKAA1 → PRKAA1 \|EP300	V(204) = K(204,1) * [PRKAA1] * [EP300] -K(204,2) * [PRKAA1 \|EP300];
R205	PRKAA1 \|EP300	EP300_p + PRKAA1	PRKAA1 \|EP300 → EP300_p + PRKAA1	V(205) = K(205,1) * [PRKAA1 \|EP300];
R206	HDAC4 + PRKAA1	PRKAA1 \|HDAC4	HDAC4 + PRKAA1 → PRKAA1 \|HDAC4	V(206) = K(206,1) * [PRKAA1] * [HDAC4] -K(206,2) * [PRKAA1 \|HDAC4];
R207	PRKAA1 \|HDAC4	HDAC4_p + PRKAA1	PRKAA1 \|HDAC4 → HDAC4_p + PRKAA1	V(207) = K(207,1) * [PRKAA1 \|HDAC4];
R208	AKT1_p + CTNNB1	AKT1_p \|CTNNB1	AKT1_p + CTNNB1 → AKT1_p \|CTNNB1	V(208) = K(208,1) * [AKT1_p] * [CTNNB1] -K(208,2) * [AKT1_p \|CTNNB1];
R209	AKT1_p \|CTNNB1	AKT1_p + CTNNB1_p	AKT1_p \|CTNNB1 → AKT1_p + CTNNB1_p	V(209) = K(209,1) * [AKT1_p \|CTNNB1];
R210	AKT1_p + STK4	AKT1_p \|STK4	AKT1_p + STK4 → AKT1_p \|STK4	V(210) = K(210,1) * [AKT1_p] * [STK4] -K(210,2) * [AKT1_p \|STK4];
R211	AKT1_p \|STK4	AKT1_p + STK4_p	AKT1_p \|STK4 → AKT1_p + STK4_p	V(211) = K(211,1) * [AKT1_p \|STK4];
R212	NR4A1 + RPS6KA3_p	RPS6KA3_p \|NR4A1	NR4A1 + RPS6KA3_p → RPS6KA3_p \|NR4A1	V(212) = K(212,1) * [RPS6KA3_p] * [NR4A1] -K(212,2) * [RPS6KA3_p \|NR4A1];
R213	RPS6KA3_p \|NR4A1	NR4A1_p + RPS6KA3_p	RPS6KA3_p \|NR4A1 → NR4A1_p + RPS6KA3_p	V(213) = K(213,1) * [RPS6KA3_p \|NR4A1];
R214	PRKAA1 + SIRT1	PRKAA1 \|SIRT1	PRKAA1 + SIRT1 → PRKAA1 \|SIRT1	V(214) = K(214,1) * [PRKAA1] * [SIRT1] -K(214,2) * [PRKAA1 \|SIRT1];
R215	PRKAA1 \|SIRT1	PRKAA1 + SIRT1_p	PRKAA1 \|SIRT1 → PRKAA1 + SIRT1_p	V(215) = K(215,1) * [PRKAA1 \|SIRT1];
R216	ROCK1 + TP53	ROCK1 \|TP53	ROCK1 + TP53 → ROCK1 \|TP53	V(216) = K(216,1) * [ROCK1] * [TP53] -K(216,2) * [ROCK1 \|TP53];
R217	ROCK1 \|TP53	ROCK1 + TP53_p	ROCK1 \|TP53 → ROCK1 + TP53_p	V(217) = K(217,1) * [ROCK1 \|TP53];
R218	MAPK1 + MAPK1_p	MAPK1_p \|MAPK1	MAPK1 + MAPK1_p → MAPK1_p \|MAPK1	V(218) = K(218,1) * [MAPK1_p] * [MAPK1] -K(218,2) * [MAPK1_p \|MAPK1];
R219	MAPK1_p \|MAPK1	MAPK1_p + MAPK1_p	MAPK1_p \|MAPK1 → MAPK1_p + MAPK1_p	V(219) = K(219,1) * [MAPK1_p \|MAPK1];
R220	MAPK9_p + SMAD3	MAPK9_p \|SMAD3	MAPK9_p + SMAD3 → MAPK9_p \|SMAD3	V(220) = K(220,1) * [MAPK9_p] * [SMAD3] -K(220,2) * [MAPK9_p \|SMAD3];
R221	MAPK9_p \|SMAD3	MAPK9_p + SMAD3_p	MAPK9_p \|SMAD3 → MAPK9_p + SMAD3_p	V(221) = K(221,1) * [MAPK9_p \|SMAD3];
R222	CDH1 + SRC_p	SRC_p \|CDH1	CDH1 + SRC_p → SRC_p \|CDH1	V(222) = K(222,1) * [SRC_p] * [CDH1] -K(222,2) * [SRC_p \|CDH1];
R223	SRC_p \|CDH1	CDH1_p + SRC_p	SRC_p \|CDH1 → CDH1_p + SRC_p	V(223) = K(223,1) * [SRC_p \|CDH1];
R224	PRKAA1 + TSC2	PRKAA1 \|TSC2	PRKAA1 + TSC2 → PRKAA1 \|TSC2	V(224) = K(224,1) * [PRKAA1] * [TSC2] -K(224,2) * [PRKAA1 \|TSC2];
R225	PRKAA1 \|TSC2	PRKAA1 + TSC2_p	PRKAA1 \|TSC2 → PRKAA1 + TSC2_p	V(225) = K(225,1) * [PRKAA1 \|TSC2];
R226	MAPK1_p + ZFP36	MAPK1_p \|ZFP36	MAPK1_p + ZFP36 → MAPK1_p \|ZFP36	V(226) = K(226,1) * [MAPK1_p] * [ZFP36] -K(226,2) * [MAPK1_p \|ZFP36];
R227	MAPK1_p \|ZFP36	MAPK1_p + ZFP36_p	MAPK1_p \|ZFP36 → MAPK1_p + ZFP36_p	V(227) = K(227,1) * [MAPK1_p \|ZFP36];
R228	MAPK1_p + RCAN1	MAPK1_p \|RCAN1	MAPK1_p + RCAN1 → MAPK1_p \|RCAN1	V(228) = K(228,1) * [MAPK1_p] * [RCAN1] -K(228,2) * [MAPK1_p \|RCAN1];
R229	MAPK1_p \|RCAN1	MAPK1_p + RCAN1_p	MAPK1_p \|RCAN1 → MAPK1_p + RCAN1_p	V(229) = K(229,1) * [MAPK1_p \|RCAN1];
R230	EGFR + JAK2_p	JAK2_p \|EGFR	EGFR + JAK2_p → JAK2_p \|EGFR	V(230) = K(230,1) * [JAK2_p] * [EGFR] -K(230,2) * [JAK2_p \|EGFR];
R231	JAK2_p \|EGFR	EGFR_p + JAK2_p	JAK2_p \|EGFR → EGFR_p + JAK2_p	V(231) = K(231,1) * [JAK2_p \|EGFR];
R232	EGFR + PKN1_p	PKN1_p \|EGFR	EGFR + PKN1_p → PKN1_p \|EGFR	V(232) = K(232,1) * [PKN1_p] * [EGFR] -K(232,2) * [PKN1_p \|EGFR];
R233	PKN1_p \|EGFR	EGFR_p + PKN1_p	PKN1_p \|EGFR → EGFR_p + PKN1_p	V(233) = K(233,1) * [PKN1_p \|EGFR];
R234	AKT1_p + MAP3K5	AKT1_p \|MAP3K5	AKT1_p + MAP3K5 → AKT1_p \|MAP3K5	V(234) = K(234,1) * [AKT1_p] * [MAP3K5] -K(234,2) * [AKT1_p \|MAP3K5];
R235	AKT1_p \|MAP3K5	AKT1_p + MAP3K5_p	AKT1_p \|MAP3K5 → AKT1_p + MAP3K5_p	V(235) = K(235,1) * [AKT1_p \|MAP3K5];
R236	AKT1_p + PARK7	AKT1_p \|PARK7	AKT1_p + PARK7 → AKT1_p \|PARK7	V(236) = K(236,1) * [AKT1_p] * [PARK7] -K(236,2) * [AKT1_p \|PARK7];
R237	AKT1_p \|PARK7	AKT1_p + PARK7_p	AKT1_p \|PARK7 → AKT1_p + PARK7_p	V(237) = K(237,1) * [AKT1_p \|PARK7];
R238	SGK1 + SP1	SGK1 \|SP1	SGK1 + SP1 → SGK1 \|SP1	V(238) = K(238,1) * [SGK1] * [SP1] -K(238,2) * [SGK1 \|SP1];
R239	SGK1 \|SP1	SGK1 + SP1_p	SGK1 \|SP1 → SGK1 + SP1_p	V(239) = K(239,1) * [SGK1 \|SP1];
R240	HIPK2 + PRKAA1	PRKAA1 \|HIPK2	HIPK2 + PRKAA1 → PRKAA1 \|HIPK2	V(240) = K(240,1) * [PRKAA1] * [HIPK2] -K(240,2) * [PRKAA1 \|HIPK2];
R241	PRKAA1 \|HIPK2	HIPK2_p + PRKAA1	PRKAA1 \|HIPK2 → HIPK2_p + PRKAA1	V(241) = K(241,1) * [PRKAA1 \|HIPK2];
R242	PROM1 + SRC_p	SRC_p \|PROM1	PROM1 + SRC_p → SRC_p \|PROM1	V(242) = K(242,1) * [SRC_p] * [PROM1] -K(242,2) * [SRC_p \|PROM1];
R243	SRC_p \|PROM1	PROM1_p + SRC_p	SRC_p \|PROM1 → PROM1_p + SRC_p	V(243) = K(243,1) * [SRC_p \|PROM1];
R244	CTNNB1 + SRC_p	SRC_p \|CTNNB1	CTNNB1 + SRC_p → SRC_p \|CTNNB1	V(244) = K(244,1) * [SRC_p] * [CTNNB1] -K(244,2) * [SRC_p \|CTNNB1];
R245	SRC_p \|CTNNB1	CTNNB1_p + SRC_p	SRC_p \|CTNNB1 → CTNNB1_p + SRC_p	V(245) = K(245,1) * [SRC_p \|CTNNB1];
R246	INSR_p + IRS2	INSR_p \|IRS2	INSR_p + IRS2 → INSR_p \|IRS2	V(246) = K(246,1) * [INSR_p] * [IRS2] -K(246,2) * [INSR_p \|IRS2];
R247	INSR_p \|IRS2	INSR_p + IRS2_p	INSR_p \|IRS2 → INSR_p + IRS2_p	V(247) = K(247,1) * [INSR_p \|IRS2];
R248	MAPK1 + SGK1	SGK1 \|MAPK1	MAPK1 + SGK1 → SGK1 \|MAPK1	V(248) = K(248,1) * [SGK1] * [MAPK1] -K(248,2) * [SGK1 \|MAPK1];
R249	SGK1 \|MAPK1	MAPK1_p + SGK1	SGK1 \|MAPK1 → MAPK1_p + SGK1	V(249) = K(249,1) * [SGK1 \|MAPK1];
R250	GHR + JAK2_p	JAK2_p \|GHR	GHR + JAK2_p → JAK2_p \|GHR	V(250) = K(250,1) * [JAK2_p] * [GHR] -K(250,2) * [JAK2_p \|GHR];
R251	JAK2_p \|GHR	GHR_p + JAK2_p	JAK2_p \|GHR → GHR_p + JAK2_p	V(251) = K(251,1) * [JAK2_p \|GHR];
R252	DDIT3 + PRKAA1	PRKAA1 \|DDIT3	DDIT3 + PRKAA1 → PRKAA1 \|DDIT3	V(252) = K(252,1) * [PRKAA1] * [DDIT3] -K(252,2) * [PRKAA1 \|DDIT3];
R253	PRKAA1 \|DDIT3	DDIT3_p + PRKAA1	PRKAA1 \|DDIT3 → DDIT3_p + PRKAA1	V(253) = K(253,1) * [PRKAA1 \|DDIT3];
R254	RPS6KA3_p + TP53	RPS6KA3_p \|TP53	RPS6KA3_p + TP53 → RPS6KA3_p \|TP53	V(254) = K(254,1) * [RPS6KA3_p] * [TP53] -K(254,2) * [RPS6KA3_p \|TP53];
R255	RPS6KA3_p \|TP53	RPS6KA3_p + TP53_p	RPS6KA3_p \|TP53 → RPS6KA3_p + TP53_p	V(255) = K(255,1) * [RPS6KA3_p \|TP53];
R256	EP300 + HIPK2_p	HIPK2_p \|EP300	EP300 + HIPK2_p → HIPK2_p \|EP300	V(256) = K(256,1) * [HIPK2_p] * [EP300] -K(256,2) * [HIPK2_p \|EP300];
R257	HIPK2_p \|EP300	EP300_p + HIPK2_p	HIPK2_p \|EP300 → EP300_p + HIPK2_p	V(257) = K(257,1) * [HIPK2_p \|EP300];
R258	NR3C1 + SGK1	SGK1 \|NR3C1	NR3C1 + SGK1 → SGK1 \|NR3C1	V(258) = K(258,1) * [SGK1] * [NR3C1] -K(258,2) * [SGK1 \|NR3C1];
R259	SGK1 \|NR3C1	NR3C1_p + SGK1	SGK1 \|NR3C1 → NR3C1_p + SGK1	V(259) = K(259,1) * [SGK1 \|NR3C1];
R260	JAK2_p + LEPR	JAK2_p \|LEPR	JAK2_p + LEPR → JAK2_p \|LEPR	V(260) = K(260,1) * [JAK2_p] * [LEPR] -K(260,2) * [JAK2_p \|LEPR];
R261	JAK2_p \|LEPR	JAK2_p + LEPR_p	JAK2_p \|LEPR → JAK2_p + LEPR_p	V(261) = K(261,1) * [JAK2_p \|LEPR];
R262	AKT1 + AKT1_p	AKT1_p \|AKT1	AKT1 + AKT1_p → AKT1_p \|AKT1	V(262) = K(262,1) * [AKT1_p] * [AKT1] -K(262,2) * [AKT1_p \|AKT1];
R263	AKT1_p \|AKT1	AKT1_p + AKT1_p	AKT1_p \|AKT1 → AKT1_p + AKT1_p	V(263) = K(263,1) * [AKT1_p \|AKT1];
R264	INSR_p + PTPN6	INSR_p \|PTPN6	INSR_p + PTPN6 → INSR_p \|PTPN6	V(264) = K(264,1) * [INSR_p] * [PTPN6] -K(264,2) * [INSR_p \|PTPN6];
R265	INSR_p \|PTPN6	INSR_p + PTPN6_p	INSR_p \|PTPN6 → INSR_p + PTPN6_p	V(265) = K(265,1) * [INSR_p \|PTPN6];
R266	EGFR_p + STAT1	EGFR_p \|STAT1	EGFR_p + STAT1 → EGFR_p \|STAT1	V(266) = K(266,1) * [EGFR_p] * [STAT1] -K(266,2) * [EGFR_p \|STAT1];
R267	EGFR_p \|STAT1	EGFR_p + STAT1_p	EGFR_p \|STAT1 → EGFR_p + STAT1_p	V(267) = K(267,1) * [EGFR_p \|STAT1];
R268	INSR_p + PTEN	INSR_p \|PTEN	INSR_p + PTEN → INSR_p \|PTEN	V(268) = K(268,1) * [INSR_p] * [PTEN] -K(268,2) * [INSR_p \|PTEN];
R269	INSR_p \|PTEN	INSR_p + PTEN_p	INSR_p \|PTEN → INSR_p + PTEN_p	V(269) = K(269,1) * [INSR_p \|PTEN];
R270	INSR_p + PIK3R1	INSR_p \|PIK3R1	INSR_p + PIK3R1 → INSR_p \|PIK3R1	V(270) = K(270,1) * [INSR_p] * [PIK3R1] -K(270,2) * [INSR_p \|PIK3R1];
R271	INSR_p \|PIK3R1	INSR_p + PIK3R1_p	INSR_p \|PIK3R1 → INSR_p + PIK3R1_p	V(271) = K(271,1) * [INSR_p \|PIK3R1];
R272	AKT1 + PIK3CA	PIK3CA \|AKT1	AKT1 + PIK3CA → PIK3CA \|AKT1	V(272) = K(272,1) * [PIK3CA] * [AKT1] -K(272,2) * [PIK3CA \|AKT1];
R273	PIK3CA \|AKT1	AKT1_p + PIK3CA	PIK3CA \|AKT1 → AKT1_p + PIK3CA	V(273) = K(273,1) * [PIK3CA \|AKT1];
R274	CDKN1B + SRC_p	SRC_p \|CDKN1B	CDKN1B + SRC_p → SRC_p \|CDKN1B	V(274) = K(274,1) * [SRC_p] * [CDKN1B] -K(274,2) * [SRC_p \|CDKN1B];
R275	SRC_p \|CDKN1B	CDKN1B_p + SRC_p	SRC_p \|CDKN1B → CDKN1B_p + SRC_p	V(275) = K(275,1) * [SRC_p \|CDKN1B];
R276	AKT1_p + CREB1	AKT1_p \|CREB1	AKT1_p + CREB1 → AKT1_p \|CREB1	V(276) = K(276,1) * [AKT1_p] * [CREB1] -K(276,2) * [AKT1_p \|CREB1];
R277	AKT1_p \|CREB1	AKT1_p + CREB1_p	AKT1_p \|CREB1 → AKT1_p + CREB1_p	V(277) = K(277,1) * [AKT1_p \|CREB1];
R278	AKT1_p + MAPK1	AKT1_p \|MAPK1	AKT1_p + MAPK1 → AKT1_p \|MAPK1	V(278) = K(278,1) * [AKT1_p] * [MAPK1] -K(278,2) * [AKT1_p \|MAPK1];
R279	AKT1_p \|MAPK1	AKT1_p + MAPK1_p	AKT1_p \|MAPK1 → AKT1_p + MAPK1_p	V(279) = K(279,1) * [AKT1_p \|MAPK1];
R280	EGFR_p + PARP1	EGFR_p \|PARP1	EGFR_p + PARP1 → EGFR_p \|PARP1	V(280) = K(280,1) * [EGFR_p] * [PARP1] -K(280,2) * [EGFR_p \|PARP1];
R281	EGFR_p \|PARP1	EGFR_p + PARP1_p	EGFR_p \|PARP1 → EGFR_p + PARP1_p	V(281) = K(281,1) * [EGFR_p \|PARP1];
R282	SIRT1 + STK4_p	STK4_p \|SIRT1	SIRT1 + STK4_p → STK4_p \|SIRT1	V(282) = K(282,1) * [STK4_p] * [SIRT1] -K(282,2) * [STK4_p \|SIRT1];
R283	STK4_p \|SIRT1	SIRT1_p + STK4_p	STK4_p \|SIRT1 → SIRT1_p + STK4_p	V(283) = K(283,1) * [STK4_p \|SIRT1];
R284	IKBKB_p + TP53	IKBKB_p \|TP53	IKBKB_p + TP53 → IKBKB_p \|TP53	V(284) = K(284,1) * [IKBKB_p] * [TP53] -K(284,2) * [IKBKB_p \|TP53];
R285	IKBKB_p \|TP53	IKBKB_p + TP53_p	IKBKB_p \|TP53 → IKBKB_p + TP53_p	V(285) = K(285,1) * [IKBKB_p \|TP53];
R286	HIPK2 + SRC_p	SRC_p \|HIPK2	HIPK2 + SRC_p → SRC_p \|HIPK2	V(286) = K(286,1) * [SRC_p] * [HIPK2] -K(286,2) * [SRC_p \|HIPK2];
R287	SRC_p \|HIPK2	HIPK2_p + SRC_p	SRC_p \|HIPK2 → HIPK2_p + SRC_p	V(287) = K(287,1) * [SRC_p \|HIPK2];
R288	ATR + TP53	ATR \|TP53	ATR + TP53 → ATR \|TP53	V(288) = K(288,1) * [ATR] * [TP53] -K(288,2) * [ATR \|TP53];
R289	ATR \|TP53	ATR + TP53_p	ATR \|TP53 → ATR + TP53_p	V(289) = K(289,1) * [ATR \|TP53];
R290	SOCS1 + SRC_p	SRC_p \|SOCS1	SOCS1 + SRC_p → SRC_p \|SOCS1	V(290) = K(290,1) * [SRC_p] * [SOCS1] -K(290,2) * [SRC_p \|SOCS1];
R291	SRC_p \|SOCS1	SOCS1_p + SRC_p	SRC_p \|SOCS1 → SOCS1_p + SRC_p	V(291) = K(291,1) * [SRC_p \|SOCS1];
R292	ATR + CREB1	ATR \|CREB1	ATR + CREB1 → ATR \|CREB1	V(292) = K(292,1) * [ATR] * [CREB1] -K(292,2) * [ATR \|CREB1];
R293	ATR \|CREB1	ATR + CREB1_p	ATR \|CREB1 → ATR + CREB1_p	V(293) = K(293,1) * [ATR \|CREB1];
R294	EGFR_p + TLR3	EGFR_p \|TLR3	EGFR_p + TLR3 → EGFR_p \|TLR3	V(294) = K(294,1) * [EGFR_p] * [TLR3] -K(294,2) * [EGFR_p \|TLR3];
R295	EGFR_p \|TLR3	EGFR_p + TLR3_p	EGFR_p \|TLR3 → EGFR_p + TLR3_p	V(295) = K(295,1) * [EGFR_p \|TLR3];
R296	RPS6KA3_p + TSC2	RPS6KA3_p \|TSC2	RPS6KA3_p + TSC2 → RPS6KA3_p \|TSC2	V(296) = K(296,1) * [RPS6KA3_p] * [TSC2] -K(296,2) * [RPS6KA3_p \|TSC2];
R297	RPS6KA3_p \|TSC2	RPS6KA3_p + TSC2_p	RPS6KA3_p \|TSC2 → RPS6KA3_p + TSC2_p	V(297) = K(297,1) * [RPS6KA3_p \|TSC2];
R298	MAPK1_p + TP53	MAPK1_p \|TP53	MAPK1_p + TP53 → MAPK1_p \|TP53	V(298) = K(298,1) * [MAPK1_p] * [TP53] -K(298,2) * [MAPK1_p \|TP53];
R299	MAPK1_p \|TP53	MAPK1_p + TP53_p	MAPK1_p \|TP53 → MAPK1_p + TP53_p	V(299) = K(299,1) * [MAPK1_p \|TP53];
R300	CDKN1B + HIPK2_p	HIPK2_p \|CDKN1B	CDKN1B + HIPK2_p → HIPK2_p \|CDKN1B	V(300) = K(300,1) * [HIPK2_p] * [CDKN1B] -K(300,2) * [HIPK2_p \|CDKN1B];
R301	HIPK2_p \|CDKN1B	CDKN1B_p + HIPK2_p	HIPK2_p \|CDKN1B → CDKN1B_p + HIPK2_p	V(301) = K(301,1) * [HIPK2_p \|CDKN1B];
R302	HIPK2_p + TP53	HIPK2_p \|TP53	HIPK2_p + TP53 → HIPK2_p \|TP53	V(302) = K(302,1) * [HIPK2_p] * [TP53] -K(302,2) * [HIPK2_p \|TP53];
R303	HIPK2_p \|TP53	HIPK2_p + TP53_p	HIPK2_p \|TP53 → HIPK2_p + TP53_p	V(303) = K(303,1) * [HIPK2_p \|TP53];
R304	PRKAA1 + PRKAA1	PRKAA1 \|PRKAA1	PRKAA1 + PRKAA1 → PRKAA1 \|PRKAA1	V(304) = K(304,1) * [PRKAA1] * [PRKAA1] -K(304,2) * [PRKAA1 \|PRKAA1];
R305	PRKAA1 \|PRKAA1	PRKAA1 + PRKAA1_p	PRKAA1 \|PRKAA1 → PRKAA1 + PRKAA1_p	V(305) = K(305,1) * [PRKAA1 \|PRKAA1];
R306	SGK1 + STAT1	SGK1 \|STAT1	SGK1 + STAT1 → SGK1 \|STAT1	V(306) = K(306,1) * [SGK1] * [STAT1] -K(306,2) * [SGK1 \|STAT1];
R307	SGK1 \|STAT1	SGK1 + STAT1_p	SGK1 \|STAT1 → SGK1 + STAT1_p	V(307) = K(307,1) * [SGK1 \|STAT1];
R308	IKBKB_p + TRIM23	IKBKB_p \|TRIM23	IKBKB_p + TRIM23 → IKBKB_p \|TRIM23	V(308) = K(308,1) * [IKBKB_p] * [TRIM23] -K(308,2) * [IKBKB_p \|TRIM23];
R309	IKBKB_p \|TRIM23	IKBKB_p + TRIM23_p	IKBKB_p \|TRIM23 → IKBKB_p + TRIM23_p	V(309) = K(309,1) * [IKBKB_p \|TRIM23];
R310	MAPK9_p + SRC	MAPK9_p \|SRC	MAPK9_p + SRC → MAPK9_p \|SRC	V(310) = K(310,1) * [MAPK9_p] * [SRC] -K(310,2) * [MAPK9_p \|SRC];
R311	MAPK9_p \|SRC	MAPK9_p + SRC_p	MAPK9_p \|SRC → MAPK9_p + SRC_p	V(311) = K(311,1) * [MAPK9_p \|SRC];
R312	ENG + SRC_p	SRC_p \|ENG	ENG + SRC_p → SRC_p \|ENG	V(312) = K(312,1) * [SRC_p] * [ENG] -K(312,2) * [SRC_p \|ENG];
R313	SRC_p \|ENG	ENG_p + SRC_p	SRC_p \|ENG → ENG_p + SRC_p	V(313) = K(313,1) * [SRC_p \|ENG];
R314	CDKN1A + MAP3K5_p	MAP3K5_p \|CDKN1A	CDKN1A + MAP3K5_p → MAP3K5_p \|CDKN1A	V(314) = K(314,1) * [MAP3K5_p] * [CDKN1A] -K(314,2) * [MAP3K5_p \|CDKN1A];
R315	MAP3K5_p \|CDKN1A	CDKN1A_p + MAP3K5_p	MAP3K5_p \|CDKN1A → CDKN1A_p + MAP3K5_p	V(315) = K(315,1) * [MAP3K5_p \|CDKN1A];
R316	CTNNB1 + EGFR_p	EGFR_p \|CTNNB1	CTNNB1 + EGFR_p → EGFR_p \|CTNNB1	V(316) = K(316,1) * [EGFR_p] * [CTNNB1] -K(316,2) * [EGFR_p \|CTNNB1];
R317	EGFR_p \|CTNNB1	CTNNB1_p + EGFR_p	EGFR_p \|CTNNB1 → CTNNB1_p + EGFR_p	V(317) = K(317,1) * [EGFR_p \|CTNNB1];
R318	SMAD3 + SRC_p	SRC_p \|SMAD3	SMAD3 + SRC_p → SRC_p \|SMAD3	V(318) = K(318,1) * [SRC_p] * [SMAD3] -K(318,2) * [SRC_p \|SMAD3];
R319	SRC_p \|SMAD3	SMAD3_p + SRC_p	SRC_p \|SMAD3 → SMAD3_p + SRC_p	V(319) = K(319,1) * [SRC_p \|SMAD3];
R320	PIK3C3 + SRC_p	SRC_p \|PIK3C3	PIK3C3 + SRC_p → SRC_p \|PIK3C3	V(320) = K(320,1) * [SRC_p] * [PIK3C3] -K(320,2) * [SRC_p \|PIK3C3];
R321	SRC_p \|PIK3C3	PIK3C3_p + SRC_p	SRC_p \|PIK3C3 → PIK3C3_p + SRC_p	V(321) = K(321,1) * [SRC_p \|PIK3C3];
R322	HIPK2_p + MDM2	HIPK2_p \|MDM2	HIPK2_p + MDM2 → HIPK2_p \|MDM2	V(322) = K(322,1) * [HIPK2_p] * [MDM2] -K(322,2) * [HIPK2_p \|MDM2];
R323	HIPK2_p \|MDM2	HIPK2_p + MDM2_p	HIPK2_p \|MDM2 → HIPK2_p + MDM2_p	V(323) = K(323,1) * [HIPK2_p \|MDM2];
R324	EP300 + ROCK2	ROCK2 \|EP300	EP300 + ROCK2 → ROCK2 \|EP300	V(324) = K(324,1) * [ROCK2] * [EP300] -K(324,2) * [ROCK2 \|EP300];
R325	ROCK2 \|EP300	EP300_p + ROCK2	ROCK2 \|EP300 → EP300_p + ROCK2	V(325) = K(325,1) * [ROCK2 \|EP300];
R326	CASP9 + SRC_p	SRC_p \|CASP9	CASP9 + SRC_p → SRC_p \|CASP9	V(326) = K(326,1) * [SRC_p] * [CASP9] -K(326,2) * [SRC_p \|CASP9];
R327	SRC_p \|CASP9	CASP9_p + SRC_p	SRC_p \|CASP9 → CASP9_p + SRC_p	V(327) = K(327,1) * [SRC_p \|CASP9];
R328	MAPK1_p + NR4A1	MAPK1_p \|NR4A1	MAPK1_p + NR4A1 → MAPK1_p \|NR4A1	V(328) = K(328,1) * [MAPK1_p] * [NR4A1] -K(328,2) * [MAPK1_p \|NR4A1];
R329	MAPK1_p \|NR4A1	MAPK1_p + NR4A1_p	MAPK1_p \|NR4A1 → MAPK1_p + NR4A1_p	V(329) = K(329,1) * [MAPK1_p \|NR4A1];
R330	PTPN6 + SRC_p	SRC_p \|PTPN6	PTPN6 + SRC_p → SRC_p \|PTPN6	V(330) = K(330,1) * [SRC_p] * [PTPN6] -K(330,2) * [SRC_p \|PTPN6];
R331	SRC_p \|PTPN6	PTPN6_p + SRC_p	SRC_p \|PTPN6 → PTPN6_p + SRC_p	V(331) = K(331,1) * [SRC_p \|PTPN6];
R332	ABCA1 + EGFR_p	EGFR_p \|ABCA1	ABCA1 + EGFR_p → EGFR_p \|ABCA1	V(332) = K(332,1) * [EGFR_p] * [ABCA1] -K(332,2) * [EGFR_p \|ABCA1];
R333	EGFR_p \|ABCA1	ABCA1_p + EGFR_p	EGFR_p \|ABCA1 → ABCA1_p + EGFR_p	V(333) = K(333,1) * [EGFR_p \|ABCA1];
R334	MAPK1_p + TXNIP	MAPK1_p \|TXNIP	MAPK1_p + TXNIP → MAPK1_p \|TXNIP	V(334) = K(334,1) * [MAPK1_p] * [TXNIP] -K(334,2) * [MAPK1_p \|TXNIP];
R335	MAPK1_p \|TXNIP	MAPK1_p + TXNIP_p	MAPK1_p \|TXNIP → MAPK1_p + TXNIP_p	V(335) = K(335,1) * [MAPK1_p \|TXNIP];
R336	EGFR_p + PKM	EGFR_p \|PKM	EGFR_p + PKM → EGFR_p \|PKM	V(336) = K(336,1) * [EGFR_p] * [PKM] -K(336,2) * [EGFR_p \|PKM];
R337	EGFR_p \|PKM	EGFR_p + PKM_p	EGFR_p \|PKM → EGFR_p + PKM_p	V(337) = K(337,1) * [EGFR_p \|PKM];
R338	PIK3CA + PIK3R1	PIK3CA \|PIK3R1	PIK3CA + PIK3R1 → PIK3CA \|PIK3R1	V(338) = K(338,1) * [PIK3CA] * [PIK3R1] -K(338,2) * [PIK3CA \|PIK3R1];
R339	PIK3CA \|PIK3R1	PIK3CA + PIK3R1_p	PIK3CA \|PIK3R1 → PIK3CA + PIK3R1_p	V(339) = K(339,1) * [PIK3CA \|PIK3R1];
R340	CDKN1B + PRKAA1	PRKAA1 \|CDKN1B	CDKN1B + PRKAA1 → PRKAA1 \|CDKN1B	V(340) = K(340,1) * [PRKAA1] * [CDKN1B] -K(340,2) * [PRKAA1 \|CDKN1B];
R341	PRKAA1 \|CDKN1B	CDKN1B_p + PRKAA1	PRKAA1 \|CDKN1B → CDKN1B_p + PRKAA1	V(341) = K(341,1) * [PRKAA1 \|CDKN1B];
R342	CREB1 + HIPK2_p	HIPK2_p \|CREB1	CREB1 + HIPK2_p → HIPK2_p \|CREB1	V(342) = K(342,1) * [HIPK2_p] * [CREB1] -K(342,2) * [HIPK2_p \|CREB1];
R343	HIPK2_p \|CREB1	CREB1_p + HIPK2_p	HIPK2_p \|CREB1 → CREB1_p + HIPK2_p	V(343) = K(343,1) * [HIPK2_p \|CREB1];
R344	PRKAA1 + TP53	PRKAA1 \|TP53	PRKAA1 + TP53 → PRKAA1 \|TP53	V(344) = K(344,1) * [PRKAA1] * [TP53] -K(344,2) * [PRKAA1 \|TP53];
R345	PRKAA1 \|TP53	PRKAA1 + TP53_p	PRKAA1 \|TP53 → PRKAA1 + TP53_p	V(345) = K(345,1) * [PRKAA1 \|TP53];
R346	JAK2_p + PTPN6_p	PTPN6_p \|JAK2_p	JAK2_p + PTPN6_p → PTPN6_p \|JAK2_p	V(346) = K(346,1) * [PTPN6_p] * [JAK2_p] -K(346,2) * [PTPN6_p \|JAK2_p];
R347	PTPN6_p \|JAK2_p	JAK2 + PTPN6_p	PTPN6_p \|JAK2_p → JAK2 + PTPN6_p	V(347) = K(347,1) * [PTPN6_p \|JAK2_p];
R348	EGFR_p + PTPN6_p	PTPN6_p \|EGFR_p	EGFR_p + PTPN6_p → PTPN6_p \|EGFR_p	V(348) = K(348,1) * [PTPN6_p] * [EGFR_p] -K(348,2) * [PTPN6_p \|EGFR_p];
R349	PTPN6_p \|EGFR_p	EGFR + PTPN6_p	PTPN6_p \|EGFR_p → EGFR + PTPN6_p	V(349) = K(349,1) * [PTPN6_p \|EGFR_p];
R350	PTEN_p + RPS6KB1_p	PTEN_p \|RPS6KB1_p	PTEN_p + RPS6KB1_p → PTEN_p \|RPS6KB1_p	V(350) = K(350,1) * [PTEN_p] * [RPS6KB1_p] -K(350,2) * [PTEN_p \|RPS6KB1_p];
R351	PTEN_p \|RPS6KB1_p	PTEN_p + RPS6KB1	PTEN_p \|RPS6KB1_p → PTEN_p + RPS6KB1	V(351) = K(351,1) * [PTEN_p \|RPS6KB1_p];
R352	DUSP1_p + MAPK9_p	DUSP1_p \|MAPK9_p	DUSP1_p + MAPK9_p → DUSP1_p \|MAPK9_p	V(352) = K(352,1) * [DUSP1_p] * [MAPK9_p] -K(352,2) * [DUSP1_p \|MAPK9_p];
R353	DUSP1_p \|MAPK9_p	DUSP1_p + MAPK9	DUSP1_p \|MAPK9_p → DUSP1_p + MAPK9	V(353) = K(353,1) * [DUSP1_p \|MAPK9_p];
R354	PTEN_p + SRC_p	PTEN_p \|SRC_p	PTEN_p + SRC_p → PTEN_p \|SRC_p	V(354) = K(354,1) * [PTEN_p] * [SRC_p] -K(354,2) * [PTEN_p \|SRC_p];
R355	PTEN_p \|SRC_p	PTEN_p + SRC	PTEN_p \|SRC_p → PTEN_p + SRC	V(355) = K(355,1) * [PTEN_p \|SRC_p];
R356	PKM_p + PTPN6_p	PTPN6_p \|PKM_p	PKM_p + PTPN6_p → PTPN6_p \|PKM_p	V(356) = K(356,1) * [PTPN6_p] * [PKM_p] -K(356,2) * [PTPN6_p \|PKM_p];
R357	PTPN6_p \|PKM_p	PKM + PTPN6_p	PTPN6_p \|PKM_p → PKM + PTPN6_p	V(357) = K(357,1) * [PTPN6_p \|PKM_p];
R358	INSR_p + PTPN6_p	PTPN6_p \|INSR_p	INSR_p + PTPN6_p → PTPN6_p \|INSR_p	V(358) = K(358,1) * [PTPN6_p] * [INSR_p] -K(358,2) * [PTPN6_p \|INSR_p];
R359	PTPN6_p \|INSR_p	INSR + PTPN6_p	PTPN6_p \|INSR_p → INSR + PTPN6_p	V(359) = K(359,1) * [PTPN6_p \|INSR_p];
R360	DUSP1_p + MAPK1_p	DUSP1_p \|MAPK1_p	DUSP1_p + MAPK1_p → DUSP1_p \|MAPK1_p	V(360) = K(360,1) * [DUSP1_p] * [MAPK1_p] -K(360,2) * [DUSP1_p \|MAPK1_p];
R361	DUSP1_p \|MAPK1_p	DUSP1_p + MAPK1	DUSP1_p \|MAPK1_p → DUSP1_p + MAPK1	V(361) = K(361,1) * [DUSP1_p \|MAPK1_p];
R362	PTPN6_p + SRC_p	PTPN6_p \|SRC_p	PTPN6_p + SRC_p → PTPN6_p \|SRC_p	V(362) = K(362,1) * [PTPN6_p] * [SRC_p] -K(362,2) * [PTPN6_p \|SRC_p];
R363	PTPN6_p \|SRC_p	PTPN6_p + SRC	PTPN6_p \|SRC_p → PTPN6_p + SRC	V(363) = K(363,1) * [PTPN6_p \|SRC_p];
R364	JAK1_p + PTPN6_p	PTPN6_p \|JAK1_p	JAK1_p + PTPN6_p → PTPN6_p \|JAK1_p	V(364) = K(364,1) * [PTPN6_p] * [JAK1_p] -K(364,2) * [PTPN6_p \|JAK1_p];
R365	PTPN6_p \|JAK1_p	JAK1 + PTPN6_p	PTPN6_p \|JAK1_p → JAK1 + PTPN6_p	V(365) = K(365,1) * [PTPN6_p \|JAK1_p];
R366	PTEN_p + SP1_p	PTEN_p \|SP1_p	PTEN_p + SP1_p → PTEN_p \|SP1_p	V(366) = K(366,1) * [PTEN_p] * [SP1_p] -K(366,2) * [PTEN_p \|SP1_p];
R367	PTEN_p \|SP1_p	PTEN_p + SP1	PTEN_p \|SP1_p → PTEN_p + SP1	V(367) = K(367,1) * [PTEN_p \|SP1_p];
R368	PTEN_p + PTEN_p	PTEN_p \|PTEN_p	PTEN_p + PTEN_p → PTEN_p \|PTEN_p	V(368) = K(368,1) * [PTEN_p] * [PTEN_p] -K(368,2) * [PTEN_p \|PTEN_p];
R369	PTEN_p \|PTEN_p	PTEN + PTEN_p	PTEN_p \|PTEN_p → PTEN + PTEN_p	V(369) = K(369,1) * [PTEN_p \|PTEN_p];
R370	CREB1_p + PTEN_p	PTEN_p \|CREB1_p	CREB1_p + PTEN_p → PTEN_p \|CREB1_p	V(370) = K(370,1) * [PTEN_p] * [CREB1_p] -K(370,2) * [PTEN_p \|CREB1_p];
R371	PTEN_p \|CREB1_p	CREB1 + PTEN_p	PTEN_p \|CREB1_p → CREB1 + PTEN_p	V(371) = K(371,1) * [PTEN_p \|CREB1_p];
R372	DUSP1_p + JUN_p	DUSP1_p \|JUN_p	DUSP1_p + JUN_p → DUSP1_p \|JUN_p	V(372) = K(372,1) * [DUSP1_p] * [JUN_p] -K(372,2) * [DUSP1_p \|JUN_p];
R373	DUSP1_p \|JUN_p	DUSP1_p + JUN	DUSP1_p \|JUN_p → DUSP1_p + JUN	V(373) = K(373,1) * [DUSP1_p \|JUN_p];
R374	CTNNB1_p + PTPN6_p	PTPN6_p \|CTNNB1_p	CTNNB1_p + PTPN6_p → PTPN6_p \|CTNNB1_p	V(374) = K(374,1) * [PTPN6_p] * [CTNNB1_p] -K(374,2) * [PTPN6_p \|CTNNB1_p];
R375	PTPN6_p \|CTNNB1_p	CTNNB1 + PTPN6_p	PTPN6_p \|CTNNB1_p → CTNNB1 + PTPN6_p	V(375) = K(375,1) * [PTPN6_p \|CTNNB1_p];
R376	IRF1 + MDM2_p	MDM2_p \|IRF1	IRF1 + MDM2_p → MDM2_p \|IRF1	V(376) = K(376,1) * [MDM2_p] * [IRF1] -K(376,2) * [MDM2_p \|IRF1];
R377	MDM2_p \|IRF1	IRF1_u + MDM2_p	MDM2_p \|IRF1 → IRF1_u + MDM2_p	V(377) = K(377,1) * [MDM2_p \|IRF1];
R378	LDLR + MYLIP	MYLIP \|LDLR	LDLR + MYLIP → MYLIP \|LDLR	V(378) = K(378,1) * [MYLIP] * [LDLR] -K(378,2) * [MYLIP \|LDLR];
R379	MYLIP \|LDLR	LDLR_u + MYLIP	MYLIP \|LDLR → LDLR_u + MYLIP	V(379) = K(379,1) * [MYLIP \|LDLR];
R380	MYLIP + VLDLR	MYLIP \|VLDLR	MYLIP + VLDLR → MYLIP \|VLDLR	V(380) = K(380,1) * [MYLIP] * [VLDLR] -K(380,2) * [MYLIP \|VLDLR];
R381	MYLIP \|VLDLR	MYLIP + VLDLR_u	MYLIP \|VLDLR → MYLIP + VLDLR_u	V(381) = K(381,1) * [MYLIP \|VLDLR];
R382	HIF1A + MDM2_p	MDM2_p \|HIF1A	HIF1A + MDM2_p → MDM2_p \|HIF1A	V(382) = K(382,1) * [MDM2_p] * [HIF1A] -K(382,2) * [MDM2_p \|HIF1A];
R383	MDM2_p \|HIF1A	HIF1A_u + MDM2_p	MDM2_p \|HIF1A → HIF1A_u + MDM2_p	V(383) = K(383,1) * [MDM2_p \|HIF1A];
R384	MDM2_p + NOTCH1	MDM2_p \|NOTCH1	MDM2_p + NOTCH1 → MDM2_p \|NOTCH1	V(384) = K(384,1) * [MDM2_p] * [NOTCH1] -K(384,2) * [MDM2_p \|NOTCH1];
R385	MDM2_p \|NOTCH1	MDM2_p + NOTCH1_u	MDM2_p \|NOTCH1 → MDM2_p + NOTCH1_u	V(385) = K(385,1) * [MDM2_p \|NOTCH1];
R386	HIF1A + RNF7	RNF7 \|HIF1A	HIF1A + RNF7 → RNF7 \|HIF1A	V(386) = K(386,1) * [RNF7] * [HIF1A] -K(386,2) * [RNF7 \|HIF1A];
R387	RNF7 \|HIF1A	HIF1A_u + RNF7	RNF7 \|HIF1A → HIF1A_u + RNF7	V(387) = K(387,1) * [RNF7 \|HIF1A];
R388	MDM2_p + NUMB	MDM2_p \|NUMB	MDM2_p + NUMB → MDM2_p \|NUMB	V(388) = K(388,1) * [MDM2_p] * [NUMB] -K(388,2) * [MDM2_p \|NUMB];
R389	MDM2_p \|NUMB	MDM2_p + NUMB_u	MDM2_p \|NUMB → MDM2_p + NUMB_u	V(389) = K(389,1) * [MDM2_p \|NUMB];
R390	DEPTOR + RNF7	RNF7 \|DEPTOR	DEPTOR + RNF7 → RNF7 \|DEPTOR	V(390) = K(390,1) * [RNF7] * [DEPTOR] -K(390,2) * [RNF7 \|DEPTOR];
R391	RNF7 \|DEPTOR	DEPTOR_u + RNF7	RNF7 \|DEPTOR → DEPTOR_u + RNF7	V(391) = K(391,1) * [RNF7 \|DEPTOR];
R392	JAK2 + SOCS1	SOCS1 \|JAK2	JAK2 + SOCS1 → SOCS1 \|JAK2	V(392) = K(392,1) * [SOCS1] * [JAK2] -K(392,2) * [SOCS1 \|JAK2];
R393	SOCS1 \|JAK2	JAK2_u + SOCS1	SOCS1 \|JAK2 → JAK2_u + SOCS1	V(393) = K(393,1) * [SOCS1 \|JAK2];
R394	CDKN1B + RNF7	RNF7 \|CDKN1B	CDKN1B + RNF7 → RNF7 \|CDKN1B	V(394) = K(394,1) * [RNF7] * [CDKN1B] -K(394,2) * [RNF7 \|CDKN1B];
R395	RNF7 \|CDKN1B	CDKN1B_u + RNF7	RNF7 \|CDKN1B → CDKN1B_u + RNF7	V(395) = K(395,1) * [RNF7 \|CDKN1B];
R396	MDM2_p + TP53	MDM2_p \|TP53	MDM2_p + TP53 → MDM2_p \|TP53	V(396) = K(396,1) * [MDM2_p] * [TP53] -K(396,2) * [MDM2_p \|TP53];
R397	MDM2_p \|TP53	MDM2_p + TP53_u	MDM2_p \|TP53 → MDM2_p + TP53_u	V(397) = K(397,1) * [MDM2_p \|TP53];
R398	MDM2_p + PPARG	MDM2_p \|PPARG	MDM2_p + PPARG → MDM2_p \|PPARG	V(398) = K(398,1) * [MDM2_p] * [PPARG] -K(398,2) * [MDM2_p \|PPARG];
R399	MDM2_p \|PPARG	MDM2_p + PPARG_u	MDM2_p \|PPARG → MDM2_p + PPARG_u	V(399) = K(399,1) * [MDM2_p \|PPARG];

R200	AKT1_p + RPS6KA3	AKT1_p \|RPS6KA3	AKT1_p + RPS6KA3 → AKT1_p \|RPS6KA3	V(200) = K(200,1) * [AKT1_p] * [RPS6KA3] -K(200,2) * [AKT1_p \|RPS6KA3];
R201	AKT1_p \|RPS6KA3	AKT1_p + RPS6KA3_p	AKT1_p \|RPS6KA3 → AKT1_p + RPS6KA3_p	V(201) = K(201,1) * [AKT1_p \|RPS6KA3];
R202	RPS6KA3 + RPS6KA3_p	RPS6KA3_p \|RPS6KA3	RPS6KA3 + RPS6KA3_p → RPS6KA3_p \|RPS6KA3	V(202) = K(202,1) * [RPS6KA3_p] * [RPS6KA3] -K(202,2) * [RPS6KA3_p \|RPS6KA3];
R203	RPS6KA3_p \|RPS6KA3	RPS6KA3_p + RPS6KA3_p	RPS6KA3_p \|RPS6KA3 → RPS6KA3_p + RPS6KA3_p	V(203) = K(203,1) * [RPS6KA3_p \|RPS6KA3];
R204	EP300 + PRKAA1	PRKAA1 \|EP300	EP300 + PRKAA1 → PRKAA1 \|EP300	V(204) = K(204,1) * [PRKAA1] * [EP300] -K(204,2) * [PRKAA1 \|EP300];
R205	PRKAA1 \|EP300	EP300_p + PRKAA1	PRKAA1 \|EP300 → EP300_p + PRKAA1	V(205) = K(205,1) * [PRKAA1 \|EP300];
R206	HDAC4 + PRKAA1	PRKAA1 \|HDAC4	HDAC4 + PRKAA1 → PRKAA1 \|HDAC4	V(206) = K(206,1) * [PRKAA1] * [HDAC4] -K(206,2) * [PRKAA1 \|HDAC4];
R207	PRKAA1 \|HDAC4	HDAC4_p + PRKAA1	PRKAA1 \|HDAC4 → HDAC4_p + PRKAA1	V(207) = K(207,1) * [PRKAA1 \|HDAC4];
R208	AKT1_p + CTNNB1	AKT1_p \|CTNNB1	AKT1_p + CTNNB1 → AKT1_p \|CTNNB1	V(208) = K(208,1) * [AKT1_p] * [CTNNB1] -K(208,2) * [AKT1_p \|CTNNB1];
R209	AKT1_p \|CTNNB1	AKT1_p + CTNNB1_p	AKT1_p \|CTNNB1 → AKT1_p + CTNNB1_p	V(209) = K(209,1) * [AKT1_p \|CTNNB1];
R210	AKT1_p + STK4	AKT1_p \|STK4	AKT1_p + STK4 → AKT1_p \|STK4	V(210) = K(210,1) * [AKT1_p] * [STK4] -K(210,2) * [AKT1_p \|STK4];
R211	AKT1_p \|STK4	AKT1_p + STK4_p	AKT1_p \|STK4 → AKT1_p + STK4_p	V(211) = K(211,1) * [AKT1_p \|STK4];
R212	NR4A1 + RPS6KA3_p	RPS6KA3_p \|NR4A1	NR4A1 + RPS6KA3_p → RPS6KA3_p \|NR4A1	V(212) = K(212,1) * [RPS6KA3_p] * [NR4A1] -K(212,2) * [RPS6KA3_p \|NR4A1];
R213	RPS6KA3_p \|NR4A1	NR4A1_p + RPS6KA3_p	RPS6KA3_p \|NR4A1 → NR4A1_p + RPS6KA3_p	V(213) = K(213,1) * [RPS6KA3_p \|NR4A1];
R214	PRKAA1 + SIRT1	PRKAA1 \|SIRT1	PRKAA1 + SIRT1 → PRKAA1 \|SIRT1	V(214) = K(214,1) * [PRKAA1] * [SIRT1] -K(214,2) * [PRKAA1 \|SIRT1];
R215	PRKAA1 \|SIRT1	PRKAA1 + SIRT1_p	PRKAA1 \|SIRT1 → PRKAA1 + SIRT1_p	V(215) = K(215,1) * [PRKAA1 \|SIRT1];
R216	ROCK1 + TP53	ROCK1 \|TP53	ROCK1 + TP53 → ROCK1 \|TP53	V(216) = K(216,1) * [ROCK1] * [TP53] -K(216,2) * [ROCK1 \|TP53];
R217	ROCK1 \|TP53	ROCK1 + TP53_p	ROCK1 \|TP53 → ROCK1 + TP53_p	V(217) = K(217,1) * [ROCK1 \|TP53];
R218	MAPK1 + MAPK1_p	MAPK1_p \|MAPK1	MAPK1 + MAPK1_p → MAPK1_p \|MAPK1	V(218) = K(218,1) * [MAPK1_p] * [MAPK1] -K(218,2) * [MAPK1_p \|MAPK1];
R219	MAPK1_p \|MAPK1	MAPK1_p + MAPK1_p	MAPK1_p \|MAPK1 → MAPK1_p + MAPK1_p	V(219) = K(219,1) * [MAPK1_p \|MAPK1];
R220	MAPK9_p + SMAD3	MAPK9_p \|SMAD3	MAPK9_p + SMAD3 → MAPK9_p \|SMAD3	V(220) = K(220,1) * [MAPK9_p] * [SMAD3] -K(220,2) * [MAPK9_p \|SMAD3];
R221	MAPK9_p \|SMAD3	MAPK9_p + SMAD3_p	MAPK9_p \|SMAD3 → MAPK9_p + SMAD3_p	V(221) = K(221,1) * [MAPK9_p \|SMAD3];
R222	CDH1 + SRC_p	SRC_p \|CDH1	CDH1 + SRC_p → SRC_p \|CDH1	V(222) = K(222,1) * [SRC_p] * [CDH1] -K(222,2) * [SRC_p \|CDH1];
R223	SRC_p \|CDH1	CDH1_p + SRC_p	SRC_p \|CDH1 → CDH1_p + SRC_p	V(223) = K(223,1) * [SRC_p \|CDH1];
R224	PRKAA1 + TSC2	PRKAA1 \|TSC2	PRKAA1 + TSC2 → PRKAA1 \|TSC2	V(224) = K(224,1) * [PRKAA1] * [TSC2] -K(224,2) * [PRKAA1 \|TSC2];
R225	PRKAA1 \|TSC2	PRKAA1 + TSC2_p	PRKAA1 \|TSC2 → PRKAA1 + TSC2_p	V(225) = K(225,1) * [PRKAA1 \|TSC2];
R226	MAPK1_p + ZFP36	MAPK1_p \|ZFP36	MAPK1_p + ZFP36 → MAPK1_p \|ZFP36	V(226) = K(226,1) * [MAPK1_p] * [ZFP36] -K(226,2) * [MAPK1_p \|ZFP36];
R227	MAPK1_p \|ZFP36	MAPK1_p + ZFP36_p	MAPK1_p \|ZFP36 → MAPK1_p + ZFP36_p	V(227) = K(227,1) * [MAPK1_p \|ZFP36];
R228	MAPK1_p + RCAN1	MAPK1_p \|RCAN1	MAPK1_p + RCAN1 → MAPK1_p \|RCAN1	V(228) = K(228,1) * [MAPK1_p] * [RCAN1] -K(228,2) * [MAPK1_p \|RCAN1];
R229	MAPK1_p \|RCAN1	MAPK1_p + RCAN1_p	MAPK1_p \|RCAN1 → MAPK1_p + RCAN1_p	V(229) = K(229,1) * [MAPK1_p \|RCAN1];
R230	EGFR + JAK2_p	JAK2_p \|EGFR	EGFR + JAK2_p → JAK2_p \|EGFR	V(230) = K(230,1) * [JAK2_p] * [EGFR] -K(230,2) * [JAK2_p \|EGFR];
R231	JAK2_p \|EGFR	EGFR_p + JAK2_p	JAK2_p \|EGFR → EGFR_p + JAK2_p	V(231) = K(231,1) * [JAK2_p \|EGFR];
R232	EGFR + PKN1_p	PKN1_p \|EGFR	EGFR + PKN1_p → PKN1_p \|EGFR	V(232) = K(232,1) * [PKN1_p] * [EGFR] -K(232,2) * [PKN1_p \|EGFR];
R233	PKN1_p \|EGFR	EGFR_p + PKN1_p	PKN1_p \|EGFR → EGFR_p + PKN1_p	V(233) = K(233,1) * [PKN1_p \|EGFR];
R234	AKT1_p + MAP3K5	AKT1_p \|MAP3K5	AKT1_p + MAP3K5 → AKT1_p \|MAP3K5	V(234) = K(234,1) * [AKT1_p] * [MAP3K5] -K(234,2) * [AKT1_p \|MAP3K5];
R235	AKT1_p \|MAP3K5	AKT1_p + MAP3K5_p	AKT1_p \|MAP3K5 → AKT1_p + MAP3K5_p	V(235) = K(235,1) * [AKT1_p \|MAP3K5];
R236	AKT1_p + PARK7	AKT1_p \|PARK7	AKT1_p + PARK7 → AKT1_p \|PARK7	V(236) = K(236,1) * [AKT1_p] * [PARK7] -K(236,2) * [AKT1_p \|PARK7];
R237	AKT1_p \|PARK7	AKT1_p + PARK7_p	AKT1_p \|PARK7 → AKT1_p + PARK7_p	V(237) = K(237,1) * [AKT1_p \|PARK7];
R238	SGK1 + SP1	SGK1 \|SP1	SGK1 + SP1 → SGK1 \|SP1	V(238) = K(238,1) * [SGK1] * [SP1] -K(238,2) * [SGK1 \|SP1];
R239	SGK1 \|SP1	SGK1 + SP1_p	SGK1 \|SP1 → SGK1 + SP1_p	V(239) = K(239,1) * [SGK1 \|SP1];
R240	HIPK2 + PRKAA1	PRKAA1 \|HIPK2	HIPK2 + PRKAA1 → PRKAA1 \|HIPK2	V(240) = K(240,1) * [PRKAA1] * [HIPK2] -K(240,2) * [PRKAA1 \|HIPK2];
R241	PRKAA1 \|HIPK2	HIPK2_p + PRKAA1	PRKAA1 \|HIPK2 → HIPK2_p + PRKAA1	V(241) = K(241,1) * [PRKAA1 \|HIPK2];
R242	PROM1 + SRC_p	SRC_p \|PROM1	PROM1 + SRC_p → SRC_p \|PROM1	V(242) = K(242,1) * [SRC_p] * [PROM1] -K(242,2) * [SRC_p \|PROM1];
R243	SRC_p \|PROM1	PROM1_p + SRC_p	SRC_p \|PROM1 → PROM1_p + SRC_p	V(243) = K(243,1) * [SRC_p \|PROM1];
R244	CTNNB1 + SRC_p	SRC_p \|CTNNB1	CTNNB1 + SRC_p → SRC_p \|CTNNB1	V(244) = K(244,1) * [SRC_p] * [CTNNB1] -K(244,2) * [SRC_p \|CTNNB1];
R245	SRC_p \|CTNNB1	CTNNB1_p + SRC_p	SRC_p \|CTNNB1 → CTNNB1_p + SRC_p	V(245) = K(245,1) * [SRC_p \|CTNNB1];
R246	INSR_p + IRS2	INSR_p \|IRS2	INSR_p + IRS2 → INSR_p \|IRS2	V(246) = K(246,1) * [INSR_p] * [IRS2] -K(246,2) * [INSR_p \|IRS2];
R247	INSR_p \|IRS2	INSR_p + IRS2_p	INSR_p \|IRS2 → INSR_p + IRS2_p	V(247) = K(247,1) * [INSR_p \|IRS2];
R248	MAPK1 + SGK1	SGK1 \|MAPK1	MAPK1 + SGK1 → SGK1 \|MAPK1	V(248) = K(248,1) * [SGK1] * [MAPK1] -K(248,2) * [SGK1 \|MAPK1];
R249	SGK1 \|MAPK1	MAPK1_p + SGK1	SGK1 \|MAPK1 → MAPK1_p + SGK1	V(249) = K(249,1) * [SGK1 \|MAPK1];
R250	GHR + JAK2_p	JAK2_p \|GHR	GHR + JAK2_p → JAK2_p \|GHR	V(250) = K(250,1) * [JAK2_p] * [GHR] -K(250,2) * [JAK2_p \|GHR];
R251	JAK2_p \|GHR	GHR_p + JAK2_p	JAK2_p \|GHR → GHR_p + JAK2_p	V(251) = K(251,1) * [JAK2_p \|GHR];
R252	DDIT3 + PRKAA1	PRKAA1 \|DDIT3	DDIT3 + PRKAA1 → PRKAA1 \|DDIT3	V(252) = K(252,1) * [PRKAA1] * [DDIT3] -K(252,2) * [PRKAA1 \|DDIT3];
R253	PRKAA1 \|DDIT3	DDIT3_p + PRKAA1	PRKAA1 \|DDIT3 → DDIT3_p + PRKAA1	V(253) = K(253,1) * [PRKAA1 \|DDIT3];
R254	RPS6KA3_p + TP53	RPS6KA3_p \|TP53	RPS6KA3_p + TP53 → RPS6KA3_p \|TP53	V(254) = K(254,1) * [RPS6KA3_p] * [TP53] -K(254,2) * [RPS6KA3_p \|TP53];
R255	RPS6KA3_p \|TP53	RPS6KA3_p + TP53_p	RPS6KA3_p \|TP53 → RPS6KA3_p + TP53_p	V(255) = K(255,1) * [RPS6KA3_p \|TP53];
R256	EP300 + HIPK2_p	HIPK2_p \|EP300	EP300 + HIPK2_p → HIPK2_p \|EP300	V(256) = K(256,1) * [HIPK2_p] * [EP300] -K(256,2) * [HIPK2_p \|EP300];
R257	HIPK2_p \|EP300	EP300_p + HIPK2_p	HIPK2_p \|EP300 → EP300_p + HIPK2_p	V(257) = K(257,1) * [HIPK2_p \|EP300];
R258	NR3C1 + SGK1	SGK1 \|NR3C1	NR3C1 + SGK1 → SGK1 \|NR3C1	V(258) = K(258,1) * [SGK1] * [NR3C1] -K(258,2) * [SGK1 \|NR3C1];
R259	SGK1 \|NR3C1	NR3C1_p + SGK1	SGK1 \|NR3C1 → NR3C1_p + SGK1	V(259) = K(259,1) * [SGK1 \|NR3C1];
R260	JAK2_p + LEPR	JAK2_p \|LEPR	JAK2_p + LEPR → JAK2_p \|LEPR	V(260) = K(260,1) * [JAK2_p] * [LEPR] -K(260,2) * [JAK2_p \|LEPR];
R261	JAK2_p \|LEPR	JAK2_p + LEPR_p	JAK2_p \|LEPR → JAK2_p + LEPR_p	V(261) = K(261,1) * [JAK2_p \|LEPR];
R262	AKT1 + AKT1_p	AKT1_p \|AKT1	AKT1 + AKT1_p → AKT1_p \|AKT1	V(262) = K(262,1) * [AKT1_p] * [AKT1] -K(262,2) * [AKT1_p \|AKT1];
R263	AKT1_p \|AKT1	AKT1_p + AKT1_p	AKT1_p \|AKT1 → AKT1_p + AKT1_p	V(263) = K(263,1) * [AKT1_p \|AKT1];
R264	INSR_p + PTPN6	INSR_p \|PTPN6	INSR_p + PTPN6 → INSR_p \|PTPN6	V(264) = K(264,1) * [INSR_p] * [PTPN6] -K(264,2) * [INSR_p \|PTPN6];
R265	INSR_p \|PTPN6	INSR_p + PTPN6_p	INSR_p \|PTPN6 → INSR_p + PTPN6_p	V(265) = K(265,1) * [INSR_p \|PTPN6];
R266	EGFR_p + STAT1	EGFR_p \|STAT1	EGFR_p + STAT1 → EGFR_p \|STAT1	V(266) = K(266,1) * [EGFR_p] * [STAT1] -K(266,2) * [EGFR_p \|STAT1];
R267	EGFR_p \|STAT1	EGFR_p + STAT1_p	EGFR_p \|STAT1 → EGFR_p + STAT1_p	V(267) = K(267,1) * [EGFR_p \|STAT1];
R268	INSR_p + PTEN	INSR_p \|PTEN	INSR_p + PTEN → INSR_p \|PTEN	V(268) = K(268,1) * [INSR_p] * [PTEN] -K(268,2) * [INSR_p \|PTEN];
R269	INSR_p \|PTEN	INSR_p + PTEN_p	INSR_p \|PTEN → INSR_p + PTEN_p	V(269) = K(269,1) * [INSR_p \|PTEN];
R270	INSR_p + PIK3R1	INSR_p \|PIK3R1	INSR_p + PIK3R1 → INSR_p \|PIK3R1	V(270) = K(270,1) * [INSR_p] * [PIK3R1] -K(270,2) * [INSR_p \|PIK3R1];
R271	INSR_p \|PIK3R1	INSR_p + PIK3R1_p	INSR_p \|PIK3R1 → INSR_p + PIK3R1_p	V(271) = K(271,1) * [INSR_p \|PIK3R1];
R272	AKT1 + PIK3CA	PIK3CA \|AKT1	AKT1 + PIK3CA → PIK3CA \|AKT1	V(272) = K(272,1) * [PIK3CA] * [AKT1] -K(272,2) * [PIK3CA \|AKT1];
R273	PIK3CA \|AKT1	AKT1_p + PIK3CA	PIK3CA \|AKT1 → AKT1_p + PIK3CA	V(273) = K(273,1) * [PIK3CA \|AKT1];
R274	CDKN1B + SRC_p	SRC_p \|CDKN1B	CDKN1B + SRC_p → SRC_p \|CDKN1B	V(274) = K(274,1) * [SRC_p] * [CDKN1B] -K(274,2) * [SRC_p \|CDKN1B];
R275	SRC_p \|CDKN1B	CDKN1B_p + SRC_p	SRC_p \|CDKN1B → CDKN1B_p + SRC_p	V(275) = K(275,1) * [SRC_p \|CDKN1B];
R276	AKT1_p + CREB1	AKT1_p \|CREB1	AKT1_p + CREB1 → AKT1_p \|CREB1	V(276) = K(276,1) * [AKT1_p] * [CREB1] -K(276,2) * [AKT1_p \|CREB1];
R277	AKT1_p \|CREB1	AKT1_p + CREB1_p	AKT1_p \|CREB1 → AKT1_p + CREB1_p	V(277) = K(277,1) * [AKT1_p \|CREB1];
R278	AKT1_p + MAPK1	AKT1_p \|MAPK1	AKT1_p + MAPK1 → AKT1_p \|MAPK1	V(278) = K(278,1) * [AKT1_p] * [MAPK1] -K(278,2) * [AKT1_p \|MAPK1];
R279	AKT1_p \|MAPK1	AKT1_p + MAPK1_p	AKT1_p \|MAPK1 → AKT1_p + MAPK1_p	V(279) = K(279,1) * [AKT1_p \|MAPK1];
R280	EGFR_p + PARP1	EGFR_p \|PARP1	EGFR_p + PARP1 → EGFR_p \|PARP1	V(280) = K(280,1) * [EGFR_p] * [PARP1] -K(280,2) * [EGFR_p \|PARP1];
R281	EGFR_p \|PARP1	EGFR_p + PARP1_p	EGFR_p \|PARP1 → EGFR_p + PARP1_p	V(281) = K(281,1) * [EGFR_p \|PARP1];
R282	SIRT1 + STK4_p	STK4_p \|SIRT1	SIRT1 + STK4_p → STK4_p \|SIRT1	V(282) = K(282,1) * [STK4_p] * [SIRT1] -K(282,2) * [STK4_p \|SIRT1];
R283	STK4_p \|SIRT1	SIRT1_p + STK4_p	STK4_p \|SIRT1 → SIRT1_p + STK4_p	V(283) = K(283,1) * [STK4_p \|SIRT1];
R284	IKBKB_p + TP53	IKBKB_p \|TP53	IKBKB_p + TP53 → IKBKB_p \|TP53	V(284) = K(284,1) * [IKBKB_p] * [TP53] -K(284,2) * [IKBKB_p \|TP53];
R285	IKBKB_p \|TP53	IKBKB_p + TP53_p	IKBKB_p \|TP53 → IKBKB_p + TP53_p	V(285) = K(285,1) * [IKBKB_p \|TP53];
R286	HIPK2 + SRC_p	SRC_p \|HIPK2	HIPK2 + SRC_p → SRC_p \|HIPK2	V(286) = K(286,1) * [SRC_p] * [HIPK2] -K(286,2) * [SRC_p \|HIPK2];
R287	SRC_p \|HIPK2	HIPK2_p + SRC_p	SRC_p \|HIPK2 → HIPK2_p + SRC_p	V(287) = K(287,1) * [SRC_p \|HIPK2];
R288	ATR + TP53	ATR \|TP53	ATR + TP53 → ATR \|TP53	V(288) = K(288,1) * [ATR] * [TP53] -K(288,2) * [ATR \|TP53];
R289	ATR \|TP53	ATR + TP53_p	ATR \|TP53 → ATR + TP53_p	V(289) = K(289,1) * [ATR \|TP53];
R290	SOCS1 + SRC_p	SRC_p \|SOCS1	SOCS1 + SRC_p → SRC_p \|SOCS1	V(290) = K(290,1) * [SRC_p] * [SOCS1] -K(290,2) * [SRC_p \|SOCS1];
R291	SRC_p \|SOCS1	SOCS1_p + SRC_p	SRC_p \|SOCS1 → SOCS1_p + SRC_p	V(291) = K(291,1) * [SRC_p \|SOCS1];
R292	ATR + CREB1	ATR \|CREB1	ATR + CREB1 → ATR \|CREB1	V(292) = K(292,1) * [ATR] * [CREB1] -K(292,2) * [ATR \|CREB1];
R293	ATR \|CREB1	ATR + CREB1_p	ATR \|CREB1 → ATR + CREB1_p	V(293) = K(293,1) * [ATR \|CREB1];
R294	EGFR_p + TLR3	EGFR_p \|TLR3	EGFR_p + TLR3 → EGFR_p \|TLR3	V(294) = K(294,1) * [EGFR_p] * [TLR3] -K(294,2) * [EGFR_p \|TLR3];
R295	EGFR_p \|TLR3	EGFR_p + TLR3_p	EGFR_p \|TLR3 → EGFR_p + TLR3_p	V(295) = K(295,1) * [EGFR_p \|TLR3];
R296	RPS6KA3_p + TSC2	RPS6KA3_p \|TSC2	RPS6KA3_p + TSC2 → RPS6KA3_p \|TSC2	V(296) = K(296,1) * [RPS6KA3_p] * [TSC2] -K(296,2) * [RPS6KA3_p \|TSC2];
R297	RPS6KA3_p \|TSC2	RPS6KA3_p + TSC2_p	RPS6KA3_p \|TSC2 → RPS6KA3_p + TSC2_p	V(297) = K(297,1) * [RPS6KA3_p \|TSC2];
R298	MAPK1_p + TP53	MAPK1_p \|TP53	MAPK1_p + TP53 → MAPK1_p \|TP53	V(298) = K(298,1) * [MAPK1_p] * [TP53] -K(298,2) * [MAPK1_p \|TP53];
R299	MAPK1_p \|TP53	MAPK1_p + TP53_p	MAPK1_p \|TP53 → MAPK1_p + TP53_p	V(299) = K(299,1) * [MAPK1_p \|TP53];
R300	CDKN1B + HIPK2_p	HIPK2_p \|CDKN1B	CDKN1B + HIPK2_p → HIPK2_p \|CDKN1B	V(300) = K(300,1) * [HIPK2_p] * [CDKN1B] -K(300,2) * [HIPK2_p \|CDKN1B];
R301	HIPK2_p \|CDKN1B	CDKN1B_p + HIPK2_p	HIPK2_p \|CDKN1B → CDKN1B_p + HIPK2_p	V(301) = K(301,1) * [HIPK2_p \|CDKN1B];
R302	HIPK2_p + TP53	HIPK2_p \|TP53	HIPK2_p + TP53 → HIPK2_p \|TP53	V(302) = K(302,1) * [HIPK2_p] * [TP53] -K(302,2) * [HIPK2_p \|TP53];
R303	HIPK2_p \|TP53	HIPK2_p + TP53_p	HIPK2_p \|TP53 → HIPK2_p + TP53_p	V(303) = K(303,1) * [HIPK2_p \|TP53];
R304	PRKAA1 + PRKAA1	PRKAA1 \|PRKAA1	PRKAA1 + PRKAA1 → PRKAA1 \|PRKAA1	V(304) = K(304,1) * [PRKAA1] * [PRKAA1] -K(304,2) * [PRKAA1 \|PRKAA1];
R305	PRKAA1 \|PRKAA1	PRKAA1 + PRKAA1_p	PRKAA1 \|PRKAA1 → PRKAA1 + PRKAA1_p	V(305) = K(305,1) * [PRKAA1 \|PRKAA1];
R306	SGK1 + STAT1	SGK1 \|STAT1	SGK1 + STAT1 → SGK1 \|STAT1	V(306) = K(306,1) * [SGK1] * [STAT1] -K(306,2) * [SGK1 \|STAT1];
R307	SGK1 \|STAT1	SGK1 + STAT1_p	SGK1 \|STAT1 → SGK1 + STAT1_p	V(307) = K(307,1) * [SGK1 \|STAT1];
R308	IKBKB_p + TRIM23	IKBKB_p \|TRIM23	IKBKB_p + TRIM23 → IKBKB_p \|TRIM23	V(308) = K(308,1) * [IKBKB_p] * [TRIM23] -K(308,2) * [IKBKB_p \|TRIM23];
R309	IKBKB_p \|TRIM23	IKBKB_p + TRIM23_p	IKBKB_p \|TRIM23 → IKBKB_p + TRIM23_p	V(309) = K(309,1) * [IKBKB_p \|TRIM23];
R310	MAPK9_p + SRC	MAPK9_p \|SRC	MAPK9_p + SRC → MAPK9_p \|SRC	V(310) = K(310,1) * [MAPK9_p] * [SRC] -K(310,2) * [MAPK9_p \|SRC];
R311	MAPK9_p \|SRC	MAPK9_p + SRC_p	MAPK9_p \|SRC → MAPK9_p + SRC_p	V(311) = K(311,1) * [MAPK9_p \|SRC];
R312	ENG + SRC_p	SRC_p \|ENG	ENG + SRC_p → SRC_p \|ENG	V(312) = K(312,1) * [SRC_p] * [ENG] -K(312,2) * [SRC_p \|ENG];
R313	SRC_p \|ENG	ENG_p + SRC_p	SRC_p \|ENG → ENG_p + SRC_p	V(313) = K(313,1) * [SRC_p \|ENG];
R314	CDKN1A + MAP3K5_p	MAP3K5_p \|CDKN1A	CDKN1A + MAP3K5_p → MAP3K5_p \|CDKN1A	V(314) = K(314,1) * [MAP3K5_p] * [CDKN1A] -K(314,2) * [MAP3K5_p \|CDKN1A];
R315	MAP3K5_p \|CDKN1A	CDKN1A_p + MAP3K5_p	MAP3K5_p \|CDKN1A → CDKN1A_p + MAP3K5_p	V(315) = K(315,1) * [MAP3K5_p \|CDKN1A];
R316	CTNNB1 + EGFR_p	EGFR_p \|CTNNB1	CTNNB1 + EGFR_p → EGFR_p \|CTNNB1	V(316) = K(316,1) * [EGFR_p] * [CTNNB1] -K(316,2) * [EGFR_p \|CTNNB1];
R317	EGFR_p \|CTNNB1	CTNNB1_p + EGFR_p	EGFR_p \|CTNNB1 → CTNNB1_p + EGFR_p	V(317) = K(317,1) * [EGFR_p \|CTNNB1];
R318	SMAD3 + SRC_p	SRC_p \|SMAD3	SMAD3 + SRC_p → SRC_p \|SMAD3	V(318) = K(318,1) * [SRC_p] * [SMAD3] -K(318,2) * [SRC_p \|SMAD3];
R319	SRC_p \|SMAD3	SMAD3_p + SRC_p	SRC_p \|SMAD3 → SMAD3_p + SRC_p	V(319) = K(319,1) * [SRC_p \|SMAD3];
R320	PIK3C3 + SRC_p	SRC_p \|PIK3C3	PIK3C3 + SRC_p → SRC_p \|PIK3C3	V(320) = K(320,1) * [SRC_p] * [PIK3C3] -K(320,2) * [SRC_p \|PIK3C3];
R321	SRC_p \|PIK3C3	PIK3C3_p + SRC_p	SRC_p \|PIK3C3 → PIK3C3_p + SRC_p	V(321) = K(321,1) * [SRC_p \|PIK3C3];
R322	HIPK2_p + MDM2	HIPK2_p \|MDM2	HIPK2_p + MDM2 → HIPK2_p \|MDM2	V(322) = K(322,1) * [HIPK2_p] * [MDM2] -K(322,2) * [HIPK2_p \|MDM2];
R323	HIPK2_p \|MDM2	HIPK2_p + MDM2_p	HIPK2_p \|MDM2 → HIPK2_p + MDM2_p	V(323) = K(323,1) * [HIPK2_p \|MDM2];
R324	EP300 + ROCK2	ROCK2 \|EP300	EP300 + ROCK2 → ROCK2 \|EP300	V(324) = K(324,1) * [ROCK2] * [EP300] -K(324,2) * [ROCK2 \|EP300];
R325	ROCK2 \|EP300	EP300_p + ROCK2	ROCK2 \|EP300 → EP300_p + ROCK2	V(325) = K(325,1) * [ROCK2 \|EP300];
R326	CASP9 + SRC_p	SRC_p \|CASP9	CASP9 + SRC_p → SRC_p \|CASP9	V(326) = K(326,1) * [SRC_p] * [CASP9] -K(326,2) * [SRC_p \|CASP9];
R327	SRC_p \|CASP9	CASP9_p + SRC_p	SRC_p \|CASP9 → CASP9_p + SRC_p	V(327) = K(327,1) * [SRC_p \|CASP9];
R328	MAPK1_p + NR4A1	MAPK1_p \|NR4A1	MAPK1_p + NR4A1 → MAPK1_p \|NR4A1	V(328) = K(328,1) * [MAPK1_p] * [NR4A1] -K(328,2) * [MAPK1_p \|NR4A1];
R329	MAPK1_p \|NR4A1	MAPK1_p + NR4A1_p	MAPK1_p \|NR4A1 → MAPK1_p + NR4A1_p	V(329) = K(329,1) * [MAPK1_p \|NR4A1];
R330	PTPN6 + SRC_p	SRC_p \|PTPN6	PTPN6 + SRC_p → SRC_p \|PTPN6	V(330) = K(330,1) * [SRC_p] * [PTPN6] -K(330,2) * [SRC_p \|PTPN6];
R331	SRC_p \|PTPN6	PTPN6_p + SRC_p	SRC_p \|PTPN6 → PTPN6_p + SRC_p	V(331) = K(331,1) * [SRC_p \|PTPN6];
R332	ABCA1 + EGFR_p	EGFR_p \|ABCA1	ABCA1 + EGFR_p → EGFR_p \|ABCA1	V(332) = K(332,1) * [EGFR_p] * [ABCA1] -K(332,2) * [EGFR_p \|ABCA1];
R333	EGFR_p \|ABCA1	ABCA1_p + EGFR_p	EGFR_p \|ABCA1 → ABCA1_p + EGFR_p	V(333) = K(333,1) * [EGFR_p \|ABCA1];
R334	MAPK1_p + TXNIP	MAPK1_p \|TXNIP	MAPK1_p + TXNIP → MAPK1_p \|TXNIP	V(334) = K(334,1) * [MAPK1_p] * [TXNIP] -K(334,2) * [MAPK1_p \|TXNIP];
R335	MAPK1_p \|TXNIP	MAPK1_p + TXNIP_p	MAPK1_p \|TXNIP → MAPK1_p + TXNIP_p	V(335) = K(335,1) * [MAPK1_p \|TXNIP];
R336	EGFR_p + PKM	EGFR_p \|PKM	EGFR_p + PKM → EGFR_p \|PKM	V(336) = K(336,1) * [EGFR_p] * [PKM] -K(336,2) * [EGFR_p \|PKM];
R337	EGFR_p \|PKM	EGFR_p + PKM_p	EGFR_p \|PKM → EGFR_p + PKM_p	V(337) = K(337,1) * [EGFR_p \|PKM];
R338	PIK3CA + PIK3R1	PIK3CA \|PIK3R1	PIK3CA + PIK3R1 → PIK3CA \|PIK3R1	V(338) = K(338,1) * [PIK3CA] * [PIK3R1] -K(338,2) * [PIK3CA \|PIK3R1];
R339	PIK3CA \|PIK3R1	PIK3CA + PIK3R1_p	PIK3CA \|PIK3R1 → PIK3CA + PIK3R1_p	V(339) = K(339,1) * [PIK3CA \|PIK3R1];
R340	CDKN1B + PRKAA1	PRKAA1 \|CDKN1B	CDKN1B + PRKAA1 → PRKAA1 \|CDKN1B	V(340) = K(340,1) * [PRKAA1] * [CDKN1B] -K(340,2) * [PRKAA1 \|CDKN1B];
R341	PRKAA1 \|CDKN1B	CDKN1B_p + PRKAA1	PRKAA1 \|CDKN1B → CDKN1B_p + PRKAA1	V(341) = K(341,1) * [PRKAA1 \|CDKN1B];
R342	CREB1 + HIPK2_p	HIPK2_p \|CREB1	CREB1 + HIPK2_p → HIPK2_p \|CREB1	V(342) = K(342,1) * [HIPK2_p] * [CREB1] -K(342,2) * [HIPK2_p \|CREB1];
R343	HIPK2_p \|CREB1	CREB1_p + HIPK2_p	HIPK2_p \|CREB1 → CREB1_p + HIPK2_p	V(343) = K(343,1) * [HIPK2_p \|CREB1];
R344	PRKAA1 + TP53	PRKAA1 \|TP53	PRKAA1 + TP53 → PRKAA1 \|TP53	V(344) = K(344,1) * [PRKAA1] * [TP53] -K(344,2) * [PRKAA1 \|TP53];
R345	PRKAA1 \|TP53	PRKAA1 + TP53_p	PRKAA1 \|TP53 → PRKAA1 + TP53_p	V(345) = K(345,1) * [PRKAA1 \|TP53];
R346	JAK2_p + PTPN6_p	PTPN6_p \|JAK2_p	JAK2_p + PTPN6_p → PTPN6_p \|JAK2_p	V(346) = K(346,1) * [PTPN6_p] * [JAK2_p] -K(346,2) * [PTPN6_p \|JAK2_p];
R347	PTPN6_p \|JAK2_p	JAK2 + PTPN6_p	PTPN6_p \|JAK2_p → JAK2 + PTPN6_p	V(347) = K(347,1) * [PTPN6_p \|JAK2_p];
R348	EGFR_p + PTPN6_p	PTPN6_p \|EGFR_p	EGFR_p + PTPN6_p → PTPN6_p \|EGFR_p	V(348) = K(348,1) * [PTPN6_p] * [EGFR_p] -K(348,2) * [PTPN6_p \|EGFR_p];
R349	PTPN6_p \|EGFR_p	EGFR + PTPN6_p	PTPN6_p \|EGFR_p → EGFR + PTPN6_p	V(349) = K(349,1) * [PTPN6_p \|EGFR_p];
R350	PTEN_p + RPS6KB1_p	PTEN_p \|RPS6KB1_p	PTEN_p + RPS6KB1_p → PTEN_p \|RPS6KB1_p	V(350) = K(350,1) * [PTEN_p] * [RPS6KB1_p] -K(350,2) * [PTEN_p \|RPS6KB1_p];
R351	PTEN_p \|RPS6KB1_p	PTEN_p + RPS6KB1	PTEN_p \|RPS6KB1_p → PTEN_p + RPS6KB1	V(351) = K(351,1) * [PTEN_p \|RPS6KB1_p];
R352	DUSP1_p + MAPK9_p	DUSP1_p \|MAPK9_p	DUSP1_p + MAPK9_p → DUSP1_p \|MAPK9_p	V(352) = K(352,1) * [DUSP1_p] * [MAPK9_p] -K(352,2) * [DUSP1_p \|MAPK9_p];
R353	DUSP1_p \|MAPK9_p	DUSP1_p + MAPK9	DUSP1_p \|MAPK9_p → DUSP1_p + MAPK9	V(353) = K(353,1) * [DUSP1_p \|MAPK9_p];
R354	PTEN_p + SRC_p	PTEN_p \|SRC_p	PTEN_p + SRC_p → PTEN_p \|SRC_p	V(354) = K(354,1) * [PTEN_p] * [SRC_p] -K(354,2) * [PTEN_p \|SRC_p];
R355	PTEN_p \|SRC_p	PTEN_p + SRC	PTEN_p \|SRC_p → PTEN_p + SRC	V(355) = K(355,1) * [PTEN_p \|SRC_p];
R356	PKM_p + PTPN6_p	PTPN6_p \|PKM_p	PKM_p + PTPN6_p → PTPN6_p \|PKM_p	V(356) = K(356,1) * [PTPN6_p] * [PKM_p] -K(356,2) * [PTPN6_p \|PKM_p];
R357	PTPN6_p \|PKM_p	PKM + PTPN6_p	PTPN6_p \|PKM_p → PKM + PTPN6_p	V(357) = K(357,1) * [PTPN6_p \|PKM_p];
R358	INSR_p + PTPN6_p	PTPN6_p \|INSR_p	INSR_p + PTPN6_p → PTPN6_p \|INSR_p	V(358) = K(358,1) * [PTPN6_p] * [INSR_p] -K(358,2) * [PTPN6_p \|INSR_p];
R359	PTPN6_p \|INSR_p	INSR + PTPN6_p	PTPN6_p \|INSR_p → INSR + PTPN6_p	V(359) = K(359,1) * [PTPN6_p \|INSR_p];
R360	DUSP1_p + MAPK1_p	DUSP1_p \|MAPK1_p	DUSP1_p + MAPK1_p → DUSP1_p \|MAPK1_p	V(360) = K(360,1) * [DUSP1_p] * [MAPK1_p] -K(360,2) * [DUSP1_p \|MAPK1_p];
R361	DUSP1_p \|MAPK1_p	DUSP1_p + MAPK1	DUSP1_p \|MAPK1_p → DUSP1_p + MAPK1	V(361) = K(361,1) * [DUSP1_p \|MAPK1_p];
R362	PTPN6_p + SRC_p	PTPN6_p \|SRC_p	PTPN6_p + SRC_p → PTPN6_p \|SRC_p	V(362) = K(362,1) * [PTPN6_p] * [SRC_p] -K(362,2) * [PTPN6_p \|SRC_p];
R363	PTPN6_p \|SRC_p	PTPN6_p + SRC	PTPN6_p \|SRC_p → PTPN6_p + SRC	V(363) = K(363,1) * [PTPN6_p \|SRC_p];
R364	JAK1_p + PTPN6_p	PTPN6_p \|JAK1_p	JAK1_p + PTPN6_p → PTPN6_p \|JAK1_p	V(364) = K(364,1) * [PTPN6_p] * [JAK1_p] -K(364,2) * [PTPN6_p \|JAK1_p];
R365	PTPN6_p \|JAK1_p	JAK1 + PTPN6_p	PTPN6_p \|JAK1_p → JAK1 + PTPN6_p	V(365) = K(365,1) * [PTPN6_p \|JAK1_p];
R366	PTEN_p + SP1_p	PTEN_p \|SP1_p	PTEN_p + SP1_p → PTEN_p \|SP1_p	V(366) = K(366,1) * [PTEN_p] * [SP1_p] -K(366,2) * [PTEN_p \|SP1_p];
R367	PTEN_p \|SP1_p	PTEN_p + SP1	PTEN_p \|SP1_p → PTEN_p + SP1	V(367) = K(367,1) * [PTEN_p \|SP1_p];
R368	PTEN_p + PTEN_p	PTEN_p \|PTEN_p	PTEN_p + PTEN_p → PTEN_p \|PTEN_p	V(368) = K(368,1) * [PTEN_p] * [PTEN_p] -K(368,2) * [PTEN_p \|PTEN_p];
R369	PTEN_p \|PTEN_p	PTEN + PTEN_p	PTEN_p \|PTEN_p → PTEN + PTEN_p	V(369) = K(369,1) * [PTEN_p \|PTEN_p];
R370	CREB1_p + PTEN_p	PTEN_p \|CREB1_p	CREB1_p + PTEN_p → PTEN_p \|CREB1_p	V(370) = K(370,1) * [PTEN_p] * [CREB1_p] -K(370,2) * [PTEN_p \|CREB1_p];
R371	PTEN_p \|CREB1_p	CREB1 + PTEN_p	PTEN_p \|CREB1_p → CREB1 + PTEN_p	V(371) = K(371,1) * [PTEN_p \|CREB1_p];
R372	DUSP1_p + JUN_p	DUSP1_p \|JUN_p	DUSP1_p + JUN_p → DUSP1_p \|JUN_p	V(372) = K(372,1) * [DUSP1_p] * [JUN_p] -K(372,2) * [DUSP1_p \|JUN_p];
R373	DUSP1_p \|JUN_p	DUSP1_p + JUN	DUSP1_p \|JUN_p → DUSP1_p + JUN	V(373) = K(373,1) * [DUSP1_p \|JUN_p];
R374	CTNNB1_p + PTPN6_p	PTPN6_p \|CTNNB1_p	CTNNB1_p + PTPN6_p → PTPN6_p \|CTNNB1_p	V(374) = K(374,1) * [PTPN6_p] * [CTNNB1_p] -K(374,2) * [PTPN6_p \|CTNNB1_p];
R375	PTPN6_p \|CTNNB1_p	CTNNB1 + PTPN6_p	PTPN6_p \|CTNNB1_p → CTNNB1 + PTPN6_p	V(375) = K(375,1) * [PTPN6_p \|CTNNB1_p];
R376	IRF1 + MDM2_p	MDM2_p \|IRF1	IRF1 + MDM2_p → MDM2_p \|IRF1	V(376) = K(376,1) * [MDM2_p] * [IRF1] -K(376,2) * [MDM2_p \|IRF1];
R377	MDM2_p \|IRF1	IRF1_u + MDM2_p	MDM2_p \|IRF1 → IRF1_u + MDM2_p	V(377) = K(377,1) * [MDM2_p \|IRF1];
R378	LDLR + MYLIP	MYLIP \|LDLR	LDLR + MYLIP → MYLIP \|LDLR	V(378) = K(378,1) * [MYLIP] * [LDLR] -K(378,2) * [MYLIP \|LDLR];
R379	MYLIP \|LDLR	LDLR_u + MYLIP	MYLIP \|LDLR → LDLR_u + MYLIP	V(379) = K(379,1) * [MYLIP \|LDLR];
R380	MYLIP + VLDLR	MYLIP \|VLDLR	MYLIP + VLDLR → MYLIP \|VLDLR	V(380) = K(380,1) * [MYLIP] * [VLDLR] -K(380,2) * [MYLIP \|VLDLR];
R381	MYLIP \|VLDLR	MYLIP + VLDLR_u	MYLIP \|VLDLR → MYLIP + VLDLR_u	V(381) = K(381,1) * [MYLIP \|VLDLR];
R382	HIF1A + MDM2_p	MDM2_p \|HIF1A	HIF1A + MDM2_p → MDM2_p \|HIF1A	V(382) = K(382,1) * [MDM2_p] * [HIF1A] -K(382,2) * [MDM2_p \|HIF1A];
R383	MDM2_p \|HIF1A	HIF1A_u + MDM2_p	MDM2_p \|HIF1A → HIF1A_u + MDM2_p	V(383) = K(383,1) * [MDM2_p \|HIF1A];
R384	MDM2_p + NOTCH1	MDM2_p \|NOTCH1	MDM2_p + NOTCH1 → MDM2_p \|NOTCH1	V(384) = K(384,1) * [MDM2_p] * [NOTCH1] -K(384,2) * [MDM2_p \|NOTCH1];
R385	MDM2_p \|NOTCH1	MDM2_p + NOTCH1_u	MDM2_p \|NOTCH1 → MDM2_p + NOTCH1_u	V(385) = K(385,1) * [MDM2_p \|NOTCH1];
R386	HIF1A + RNF7	RNF7 \|HIF1A	HIF1A + RNF7 → RNF7 \|HIF1A	V(386) = K(386,1) * [RNF7] * [HIF1A] -K(386,2) * [RNF7 \|HIF1A];
R387	RNF7 \|HIF1A	HIF1A_u + RNF7	RNF7 \|HIF1A → HIF1A_u + RNF7	V(387) = K(387,1) * [RNF7 \|HIF1A];
R388	MDM2_p + NUMB	MDM2_p \|NUMB	MDM2_p + NUMB → MDM2_p \|NUMB	V(388) = K(388,1) * [MDM2_p] * [NUMB] -K(388,2) * [MDM2_p \|NUMB];
R389	MDM2_p \|NUMB	MDM2_p + NUMB_u	MDM2_p \|NUMB → MDM2_p + NUMB_u	V(389) = K(389,1) * [MDM2_p \|NUMB];
R390	DEPTOR + RNF7	RNF7 \|DEPTOR	DEPTOR + RNF7 → RNF7 \|DEPTOR	V(390) = K(390,1) * [RNF7] * [DEPTOR] -K(390,2) * [RNF7 \|DEPTOR];
R391	RNF7 \|DEPTOR	DEPTOR_u + RNF7	RNF7 \|DEPTOR → DEPTOR_u + RNF7	V(391) = K(391,1) * [RNF7 \|DEPTOR];
R392	JAK2 + SOCS1	SOCS1 \|JAK2	JAK2 + SOCS1 → SOCS1 \|JAK2	V(392) = K(392,1) * [SOCS1] * [JAK2] -K(392,2) * [SOCS1 \|JAK2];
R393	SOCS1 \|JAK2	JAK2_u + SOCS1	SOCS1 \|JAK2 → JAK2_u + SOCS1	V(393) = K(393,1) * [SOCS1 \|JAK2];
R394	CDKN1B + RNF7	RNF7 \|CDKN1B	CDKN1B + RNF7 → RNF7 \|CDKN1B	V(394) = K(394,1) * [RNF7] * [CDKN1B] -K(394,2) * [RNF7 \|CDKN1B];
R395	RNF7 \|CDKN1B	CDKN1B_u + RNF7	RNF7 \|CDKN1B → CDKN1B_u + RNF7	V(395) = K(395,1) * [RNF7 \|CDKN1B];
R396	MDM2_p + TP53	MDM2_p \|TP53	MDM2_p + TP53 → MDM2_p \|TP53	V(396) = K(396,1) * [MDM2_p] * [TP53] -K(396,2) * [MDM2_p \|TP53];
R397	MDM2_p \|TP53	MDM2_p + TP53_u	MDM2_p \|TP53 → MDM2_p + TP53_u	V(397) = K(397,1) * [MDM2_p \|TP53];
R398	MDM2_p + PPARG	MDM2_p \|PPARG	MDM2_p + PPARG → MDM2_p \|PPARG	V(398) = K(398,1) * [MDM2_p] * [PPARG] -K(398,2) * [MDM2_p \|PPARG];
R399	MDM2_p \|PPARG	MDM2_p + PPARG_u	MDM2_p \|PPARG → MDM2_p + PPARG_u	V(399) = K(399,1) * [MDM2_p \|PPARG];