Pericyte Cell_Parametric ODE Equations

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Reaction ID	Reactants	Products	Original Text	ODE Equations
R1	SMAD2_p + SMAD4_p	SIGNOR-C8	SMAD2_p + SMAD4_p → SIGNOR-C8	V(1) = K(1,1) * [SMAD2_p] * [SMAD4_p] -K(1,2) * [SIGNOR-C8];
R2	JUN_p + SMAD4_p	SIGNOR-C10	JUN_p + SMAD4_p → SIGNOR-C10	V(2) = K(2,1) * [SMAD4_p] * [JUN_p] -K(2,2) * [SIGNOR-C10];
R3	SP1_p + STAT3_p	SIGNOR-C74	SP1_p + STAT3_p → SIGNOR-C74	V(3) = K(3,1) * [STAT3_p] * [SP1_p] -K(3,2) * [SIGNOR-C74];
R4	STAT1_p + STAT3_p	SIGNOR-C118	STAT1_p + STAT3_p → SIGNOR-C118	V(4) = K(4,1) * [STAT1_p] * [STAT3_p] -K(4,2) * [SIGNOR-C118];
R5	JAK1_p + SIGNOR-C118	SIGNOR-C120	JAK1_p + SIGNOR-C118 → SIGNOR-C120	V(5) = K(5,1) * [SIGNOR-C118] * [JAK1_p] -K(5,2) * [SIGNOR-C120];
R6	FOS_p + FOS_p + FOS_p + FOS_p + JUN_p + JUN_p + JUN_p + JUN_p	SIGNOR-C154	FOS_p + FOS_p + FOS_p + FOS_p + JUN_p + JUN_p + JUN_p + JUN_p → SIGNOR-C154	V(6) = K(6,1) * [FOS_p] * [JUN_p] * [JUN_p] * [FOS_p] * [JUN_p] * [FOS_p] * [FOS_p] * [JUN_p] -K(6,2) * [SIGNOR-C154];
R7	PIK3CA_u + PIK3R1_p	SIGNOR-C156	PIK3CA_u + PIK3R1_p → SIGNOR-C156	V(7) = K(7,1) * [PIK3R1_p] * [PIK3CA_u] -K(7,2) * [SIGNOR-C156];
R8	EP300 + MAPK1_p	MAPK1_p \|EP300	EP300 + MAPK1_p → MAPK1_p \|EP300	V(8) = K(8,1) * [MAPK1_p] * [EP300] -K(8,2) * [MAPK1_p \|EP300];
R9	MAPK1_p \|EP300	EP300_p + MAPK1_p	MAPK1_p \|EP300 → EP300_p + MAPK1_p	V(9) = K(9,1) * [MAPK1_p \|EP300];
R10	HIF1A + MAPK1_p	MAPK1_p \|HIF1A	HIF1A + MAPK1_p → MAPK1_p \|HIF1A	V(10) = K(10,1) * [MAPK1_p] * [HIF1A] -K(10,2) * [MAPK1_p \|HIF1A];
R11	MAPK1_p \|HIF1A	HIF1A_p + MAPK1_p	MAPK1_p \|HIF1A → HIF1A_p + MAPK1_p	V(11) = K(11,1) * [MAPK1_p \|HIF1A];
R12	MAPK1_p + NR3C1	MAPK1_p \|NR3C1	MAPK1_p + NR3C1 → MAPK1_p \|NR3C1	V(12) = K(12,1) * [MAPK1_p] * [NR3C1] -K(12,2) * [MAPK1_p \|NR3C1];
R13	MAPK1_p \|NR3C1	MAPK1_p + NR3C1_p	MAPK1_p \|NR3C1 → MAPK1_p + NR3C1_p	V(13) = K(13,1) * [MAPK1_p \|NR3C1];
R14	MAPK1_p + PRDX6	MAPK1_p \|PRDX6	MAPK1_p + PRDX6 → MAPK1_p \|PRDX6	V(14) = K(14,1) * [MAPK1_p] * [PRDX6] -K(14,2) * [MAPK1_p \|PRDX6];
R15	MAPK1_p \|PRDX6	MAPK1_p + PRDX6_p	MAPK1_p \|PRDX6 → MAPK1_p + PRDX6_p	V(15) = K(15,1) * [MAPK1_p \|PRDX6];
R16	KIT_p + PTPN11	KIT_p \|PTPN11	KIT_p + PTPN11 → KIT_p \|PTPN11	V(16) = K(16,1) * [KIT_p] * [PTPN11] -K(16,2) * [KIT_p \|PTPN11];
R17	KIT_p \|PTPN11	KIT_p + PTPN11_p	KIT_p \|PTPN11 → KIT_p + PTPN11_p	V(17) = K(17,1) * [KIT_p \|PTPN11];
R18	EGFR + EGFR_p	EGFR_p \|EGFR	EGFR + EGFR_p → EGFR_p \|EGFR	V(18) = K(18,1) * [EGFR_p] * [EGFR] -K(18,2) * [EGFR_p \|EGFR];
R19	EGFR_p \|EGFR	EGFR_p + EGFR_p	EGFR_p \|EGFR → EGFR_p + EGFR_p	V(19) = K(19,1) * [EGFR_p \|EGFR];
R20	CDKN1B + MAPK1_p	MAPK1_p \|CDKN1B	CDKN1B + MAPK1_p → MAPK1_p \|CDKN1B	V(20) = K(20,1) * [MAPK1_p] * [CDKN1B] -K(20,2) * [MAPK1_p \|CDKN1B];
R21	MAPK1_p \|CDKN1B	CDKN1B_p + MAPK1_p	MAPK1_p \|CDKN1B → CDKN1B_p + MAPK1_p	V(21) = K(21,1) * [MAPK1_p \|CDKN1B];
R22	MAPK1_p + SMAD4	MAPK1_p \|SMAD4	MAPK1_p + SMAD4 → MAPK1_p \|SMAD4	V(22) = K(22,1) * [MAPK1_p] * [SMAD4] -K(22,2) * [MAPK1_p \|SMAD4];
R23	MAPK1_p \|SMAD4	MAPK1_p + SMAD4_p	MAPK1_p \|SMAD4 → MAPK1_p + SMAD4_p	V(23) = K(23,1) * [MAPK1_p \|SMAD4];
R24	JUN + MAPK1_p	MAPK1_p \|JUN	JUN + MAPK1_p → MAPK1_p \|JUN	V(24) = K(24,1) * [MAPK1_p] * [JUN] -K(24,2) * [MAPK1_p \|JUN];
R25	MAPK1_p \|JUN	JUN_p + MAPK1_p	MAPK1_p \|JUN → JUN_p + MAPK1_p	V(25) = K(25,1) * [MAPK1_p \|JUN];
R26	FOS + MAPK1_p	MAPK1_p \|FOS	FOS + MAPK1_p → MAPK1_p \|FOS	V(26) = K(26,1) * [MAPK1_p] * [FOS] -K(26,2) * [MAPK1_p \|FOS];
R27	MAPK1_p \|FOS	FOS_p + MAPK1_p	MAPK1_p \|FOS → FOS_p + MAPK1_p	V(27) = K(27,1) * [MAPK1_p \|FOS];
R28	KDR + KDR_p	KDR_p \|KDR	KDR + KDR_p → KDR_p \|KDR	V(28) = K(28,1) * [KDR_p] * [KDR] -K(28,2) * [KDR_p \|KDR];
R29	KDR_p \|KDR	KDR_p + KDR_p	KDR_p \|KDR → KDR_p + KDR_p	V(29) = K(29,1) * [KDR_p \|KDR];
R30	BCL2 + MAPK8_p	MAPK8_p \|BCL2	BCL2 + MAPK8_p → MAPK8_p \|BCL2	V(30) = K(30,1) * [MAPK8_p] * [BCL2] -K(30,2) * [MAPK8_p \|BCL2];
R31	MAPK8_p \|BCL2	BCL2_p + MAPK8_p	MAPK8_p \|BCL2 → BCL2_p + MAPK8_p	V(31) = K(31,1) * [MAPK8_p \|BCL2];
R32	MAPK1_p + SMAD2	MAPK1_p \|SMAD2	MAPK1_p + SMAD2 → MAPK1_p \|SMAD2	V(32) = K(32,1) * [MAPK1_p] * [SMAD2] -K(32,2) * [MAPK1_p \|SMAD2];
R33	MAPK1_p \|SMAD2	MAPK1_p + SMAD2_p	MAPK1_p \|SMAD2 → MAPK1_p + SMAD2_p	V(33) = K(33,1) * [MAPK1_p \|SMAD2];
R34	CTNNB1 + KIT_p	KIT_p \|CTNNB1	CTNNB1 + KIT_p → KIT_p \|CTNNB1	V(34) = K(34,1) * [KIT_p] * [CTNNB1] -K(34,2) * [KIT_p \|CTNNB1];
R35	KIT_p \|CTNNB1	CTNNB1_p + KIT_p	KIT_p \|CTNNB1 → CTNNB1_p + KIT_p	V(35) = K(35,1) * [KIT_p \|CTNNB1];
R36	MAPK1_p + RORA	MAPK1_p \|RORA	MAPK1_p + RORA → MAPK1_p \|RORA	V(36) = K(36,1) * [MAPK1_p] * [RORA] -K(36,2) * [MAPK1_p \|RORA];
R37	MAPK1_p \|RORA	MAPK1_p + RORA_p	MAPK1_p \|RORA → MAPK1_p + RORA_p	V(37) = K(37,1) * [MAPK1_p \|RORA];
R38	JUN + MAPK9_p	MAPK9_p \|JUN	JUN + MAPK9_p → MAPK9_p \|JUN	V(38) = K(38,1) * [MAPK9_p] * [JUN] -K(38,2) * [MAPK9_p \|JUN];
R39	MAPK9_p \|JUN	JUN_p + MAPK9_p	MAPK9_p \|JUN → JUN_p + MAPK9_p	V(39) = K(39,1) * [MAPK9_p \|JUN];
R40	BCL2 + MAPK1_p	MAPK1_p \|BCL2	BCL2 + MAPK1_p → MAPK1_p \|BCL2	V(40) = K(40,1) * [MAPK1_p] * [BCL2] -K(40,2) * [MAPK1_p \|BCL2];
R41	MAPK1_p \|BCL2	BCL2_p + MAPK1_p	MAPK1_p \|BCL2 → BCL2_p + MAPK1_p	V(41) = K(41,1) * [MAPK1_p \|BCL2];
R42	MAPK1_p + SREBF1	MAPK1_p \|SREBF1	MAPK1_p + SREBF1 → MAPK1_p \|SREBF1	V(42) = K(42,1) * [MAPK1_p] * [SREBF1] -K(42,2) * [MAPK1_p \|SREBF1];
R43	MAPK1_p \|SREBF1	MAPK1_p + SREBF1_p	MAPK1_p \|SREBF1 → MAPK1_p + SREBF1_p	V(43) = K(43,1) * [MAPK1_p \|SREBF1];
R44	JAK1_p + STAT1	JAK1_p \|STAT1	JAK1_p + STAT1 → JAK1_p \|STAT1	V(44) = K(44,1) * [JAK1_p] * [STAT1] -K(44,2) * [JAK1_p \|STAT1];
R45	JAK1_p \|STAT1	JAK1_p + STAT1_p	JAK1_p \|STAT1 → JAK1_p + STAT1_p	V(45) = K(45,1) * [JAK1_p \|STAT1];
R46	DUSP1 + MAPK1_p	MAPK1_p \|DUSP1	DUSP1 + MAPK1_p → MAPK1_p \|DUSP1	V(46) = K(46,1) * [MAPK1_p] * [DUSP1] -K(46,2) * [MAPK1_p \|DUSP1];
R47	MAPK1_p \|DUSP1	DUSP1_p + MAPK1_p	MAPK1_p \|DUSP1 → DUSP1_p + MAPK1_p	V(47) = K(47,1) * [MAPK1_p \|DUSP1];
R48	MAPK1_p + NR3C2	MAPK1_p \|NR3C2	MAPK1_p + NR3C2 → MAPK1_p \|NR3C2	V(48) = K(48,1) * [MAPK1_p] * [NR3C2] -K(48,2) * [MAPK1_p \|NR3C2];
R49	MAPK1_p \|NR3C2	MAPK1_p + NR3C2_p	MAPK1_p \|NR3C2 → MAPK1_p + NR3C2_p	V(49) = K(49,1) * [MAPK1_p \|NR3C2];
R50	MAPK8_p + MAPK9	MAPK8_p \|MAPK9	MAPK8_p + MAPK9 → MAPK8_p \|MAPK9	V(50) = K(50,1) * [MAPK8_p] * [MAPK9] -K(50,2) * [MAPK8_p \|MAPK9];
R51	MAPK8_p \|MAPK9	MAPK8_p + MAPK9_p	MAPK8_p \|MAPK9 → MAPK8_p + MAPK9_p	V(51) = K(51,1) * [MAPK8_p \|MAPK9];
R52	MAPK1_p + TSC2	MAPK1_p \|TSC2	MAPK1_p + TSC2 → MAPK1_p \|TSC2	V(52) = K(52,1) * [MAPK1_p] * [TSC2] -K(52,2) * [MAPK1_p \|TSC2];
R53	MAPK1_p \|TSC2	MAPK1_p + TSC2_p	MAPK1_p \|TSC2 → MAPK1_p + TSC2_p	V(53) = K(53,1) * [MAPK1_p \|TSC2];
R54	KIT + KIT_p	KIT_p \|KIT	KIT + KIT_p → KIT_p \|KIT	V(54) = K(54,1) * [KIT_p] * [KIT] -K(54,2) * [KIT_p \|KIT];
R55	KIT_p \|KIT	KIT_p + KIT_p	KIT_p \|KIT → KIT_p + KIT_p	V(55) = K(55,1) * [KIT_p \|KIT];
R56	MAPK1_p + RHOA	MAPK1_p \|RHOA	MAPK1_p + RHOA → MAPK1_p \|RHOA	V(56) = K(56,1) * [MAPK1_p] * [RHOA] -K(56,2) * [MAPK1_p \|RHOA];
R57	MAPK1_p \|RHOA	MAPK1_p + RHOA_p	MAPK1_p \|RHOA → MAPK1_p + RHOA_p	V(57) = K(57,1) * [MAPK1_p \|RHOA];
R58	ATR + PARP1	ATR \|PARP1	ATR + PARP1 → ATR \|PARP1	V(58) = K(58,1) * [ATR] * [PARP1] -K(58,2) * [ATR \|PARP1];
R59	ATR \|PARP1	ATR + PARP1_p	ATR \|PARP1 → ATR + PARP1_p	V(59) = K(59,1) * [ATR \|PARP1];
R60	MAPK8_p + NR3C1	MAPK8_p \|NR3C1	MAPK8_p + NR3C1 → MAPK8_p \|NR3C1	V(60) = K(60,1) * [MAPK8_p] * [NR3C1] -K(60,2) * [MAPK8_p \|NR3C1];
R61	MAPK8_p \|NR3C1	MAPK8_p + NR3C1_p	MAPK8_p \|NR3C1 → MAPK8_p + NR3C1_p	V(61) = K(61,1) * [MAPK8_p \|NR3C1];
R62	MAPK1_p + PPARG	MAPK1_p \|PPARG	MAPK1_p + PPARG → MAPK1_p \|PPARG	V(62) = K(62,1) * [MAPK1_p] * [PPARG] -K(62,2) * [MAPK1_p \|PPARG];
R63	MAPK1_p \|PPARG	MAPK1_p + PPARG_p	MAPK1_p \|PPARG → MAPK1_p + PPARG_p	V(63) = K(63,1) * [MAPK1_p \|PPARG];
R64	MAPK1_p + TFEB	MAPK1_p \|TFEB	MAPK1_p + TFEB → MAPK1_p \|TFEB	V(64) = K(64,1) * [MAPK1_p] * [TFEB] -K(64,2) * [MAPK1_p \|TFEB];
R65	MAPK1_p \|TFEB	MAPK1_p + TFEB_p	MAPK1_p \|TFEB → MAPK1_p + TFEB_p	V(65) = K(65,1) * [MAPK1_p \|TFEB];
R66	ATR + MDM2	ATR \|MDM2	ATR + MDM2 → ATR \|MDM2	V(66) = K(66,1) * [ATR] * [MDM2] -K(66,2) * [ATR \|MDM2];
R67	ATR \|MDM2	ATR + MDM2_p	ATR \|MDM2 → ATR + MDM2_p	V(67) = K(67,1) * [ATR \|MDM2];
R68	MAPK1_p + SIGNOR-C154	MAPK1_p \|SIGNOR-C154	MAPK1_p + SIGNOR-C154 → MAPK1_p \|SIGNOR-C154	V(68) = K(68,1) * [MAPK1_p] * [SIGNOR-C154] -K(68,2) * [MAPK1_p \|SIGNOR-C154];
R69	MAPK1_p \|SIGNOR-C154	MAPK1_p + SIGNOR-C154_p	MAPK1_p \|SIGNOR-C154 → MAPK1_p + SIGNOR-C154_p	V(69) = K(69,1) * [MAPK1_p \|SIGNOR-C154];
R70	CTNNB1 + MAPK8_p	MAPK8_p \|CTNNB1	CTNNB1 + MAPK8_p → MAPK8_p \|CTNNB1	V(70) = K(70,1) * [MAPK8_p] * [CTNNB1] -K(70,2) * [MAPK8_p \|CTNNB1];
R71	MAPK8_p \|CTNNB1	CTNNB1_p + MAPK8_p	MAPK8_p \|CTNNB1 → CTNNB1_p + MAPK8_p	V(71) = K(71,1) * [MAPK8_p \|CTNNB1];
R72	HIPK2 + HIPK2_p	HIPK2_p \|HIPK2	HIPK2 + HIPK2_p → HIPK2_p \|HIPK2	V(72) = K(72,1) * [HIPK2_p] * [HIPK2] -K(72,2) * [HIPK2_p \|HIPK2];
R73	HIPK2_p \|HIPK2	HIPK2_p + HIPK2_p	HIPK2_p \|HIPK2 → HIPK2_p + HIPK2_p	V(73) = K(73,1) * [HIPK2_p \|HIPK2];
R74	MAPK8_p + PKM	MAPK8_p \|PKM	MAPK8_p + PKM → MAPK8_p \|PKM	V(74) = K(74,1) * [MAPK8_p] * [PKM] -K(74,2) * [MAPK8_p \|PKM];
R75	MAPK8_p \|PKM	MAPK8_p + PKM_p	MAPK8_p \|PKM → MAPK8_p + PKM_p	V(75) = K(75,1) * [MAPK8_p \|PKM];
R76	EGFR + MAPK1_p	MAPK1_p \|EGFR	EGFR + MAPK1_p → MAPK1_p \|EGFR	V(76) = K(76,1) * [MAPK1_p] * [EGFR] -K(76,2) * [MAPK1_p \|EGFR];
R77	MAPK1_p \|EGFR	EGFR_p + MAPK1_p	MAPK1_p \|EGFR → EGFR_p + MAPK1_p	V(77) = K(77,1) * [MAPK1_p \|EGFR];
R78	MAPK8_p + STAT6	MAPK8_p \|STAT6	MAPK8_p + STAT6 → MAPK8_p \|STAT6	V(78) = K(78,1) * [MAPK8_p] * [STAT6] -K(78,2) * [MAPK8_p \|STAT6];
R79	MAPK8_p \|STAT6	MAPK8_p + STAT6_p	MAPK8_p \|STAT6 → MAPK8_p + STAT6_p	V(79) = K(79,1) * [MAPK8_p \|STAT6];
R80	DNMT1 + PRKAA1	PRKAA1 \|DNMT1	DNMT1 + PRKAA1 → PRKAA1 \|DNMT1	V(80) = K(80,1) * [PRKAA1] * [DNMT1] -K(80,2) * [PRKAA1 \|DNMT1];
R81	PRKAA1 \|DNMT1	DNMT1_p + PRKAA1	PRKAA1 \|DNMT1 → DNMT1_p + PRKAA1	V(81) = K(81,1) * [PRKAA1 \|DNMT1];
R82	TEK + TEK_p	TEK_p \|TEK	TEK + TEK_p → TEK_p \|TEK	V(82) = K(82,1) * [TEK_p] * [TEK] -K(82,2) * [TEK_p \|TEK];
R83	TEK_p \|TEK	TEK_p + TEK_p	TEK_p \|TEK → TEK_p + TEK_p	V(83) = K(83,1) * [TEK_p \|TEK];
R84	MAPK8_p + PPARG	MAPK8_p \|PPARG	MAPK8_p + PPARG → MAPK8_p \|PPARG	V(84) = K(84,1) * [MAPK8_p] * [PPARG] -K(84,2) * [MAPK8_p \|PPARG];
R85	MAPK8_p \|PPARG	MAPK8_p + PPARG_p	MAPK8_p \|PPARG → MAPK8_p + PPARG_p	V(85) = K(85,1) * [MAPK8_p \|PPARG];
R86	MAPK1_p + SP1	MAPK1_p \|SP1	MAPK1_p + SP1 → MAPK1_p \|SP1	V(86) = K(86,1) * [MAPK1_p] * [SP1] -K(86,2) * [MAPK1_p \|SP1];
R87	MAPK1_p \|SP1	MAPK1_p + SP1_p	MAPK1_p \|SP1 → MAPK1_p + SP1_p	V(87) = K(87,1) * [MAPK1_p \|SP1];
R88	CDKN1A + MAPK8_p	MAPK8_p \|CDKN1A	CDKN1A + MAPK8_p → MAPK8_p \|CDKN1A	V(88) = K(88,1) * [MAPK8_p] * [CDKN1A] -K(88,2) * [MAPK8_p \|CDKN1A];
R89	MAPK8_p \|CDKN1A	CDKN1A_p + MAPK8_p	MAPK8_p \|CDKN1A → CDKN1A_p + MAPK8_p	V(89) = K(89,1) * [MAPK8_p \|CDKN1A];
R90	CDKN1A + MAPK1_p	MAPK1_p \|CDKN1A	CDKN1A + MAPK1_p → MAPK1_p \|CDKN1A	V(90) = K(90,1) * [MAPK1_p] * [CDKN1A] -K(90,2) * [MAPK1_p \|CDKN1A];
R91	MAPK1_p \|CDKN1A	CDKN1A_p + MAPK1_p	MAPK1_p \|CDKN1A → CDKN1A_p + MAPK1_p	V(91) = K(91,1) * [MAPK1_p \|CDKN1A];
R92	JUN + MAPK8_p	MAPK8_p \|JUN	JUN + MAPK8_p → MAPK8_p \|JUN	V(92) = K(92,1) * [MAPK8_p] * [JUN] -K(92,2) * [MAPK8_p \|JUN];
R93	MAPK8_p \|JUN	JUN_p + MAPK8_p	MAPK8_p \|JUN → JUN_p + MAPK8_p	V(93) = K(93,1) * [MAPK8_p \|JUN];
R94	JAK1_p + STAT3	JAK1_p \|STAT3	JAK1_p + STAT3 → JAK1_p \|STAT3	V(94) = K(94,1) * [JAK1_p] * [STAT3] -K(94,2) * [JAK1_p \|STAT3];
R95	JAK1_p \|STAT3	JAK1_p + STAT3_p	JAK1_p \|STAT3 → JAK1_p + STAT3_p	V(95) = K(95,1) * [JAK1_p \|STAT3];
R96	MAPK1_p + PARP1	MAPK1_p \|PARP1	MAPK1_p + PARP1 → MAPK1_p \|PARP1	V(96) = K(96,1) * [MAPK1_p] * [PARP1] -K(96,2) * [MAPK1_p \|PARP1];
R97	MAPK1_p \|PARP1	MAPK1_p + PARP1_p	MAPK1_p \|PARP1 → MAPK1_p + PARP1_p	V(97) = K(97,1) * [MAPK1_p \|PARP1];
R98	EGFR_p + SIGNOR-C120	EGFR_p \|SIGNOR-C120	EGFR_p + SIGNOR-C120 → EGFR_p \|SIGNOR-C120	V(98) = K(98,1) * [EGFR_p] * [SIGNOR-C120] -K(98,2) * [EGFR_p \|SIGNOR-C120];
R99	EGFR_p \|SIGNOR-C120	EGFR_p + SIGNOR-C120_p	EGFR_p \|SIGNOR-C120 → EGFR_p + SIGNOR-C120_p	V(99) = K(99,1) * [EGFR_p \|SIGNOR-C120];
R100	MAPK8_p + SP1	MAPK8_p \|SP1	MAPK8_p + SP1 → MAPK8_p \|SP1	V(100) = K(100,1) * [MAPK8_p] * [SP1] -K(100,2) * [MAPK8_p \|SP1];
R101	MAPK8_p \|SP1	MAPK8_p + SP1_p	MAPK8_p \|SP1 → MAPK8_p + SP1_p	V(101) = K(101,1) * [MAPK8_p \|SP1];
R102	EGFR_p + PPARG	EGFR_p \|PPARG	EGFR_p + PPARG → EGFR_p \|PPARG	V(102) = K(102,1) * [EGFR_p] * [PPARG] -K(102,2) * [EGFR_p \|PPARG];
R103	EGFR_p \|PPARG	EGFR_p + PPARG_p	EGFR_p \|PPARG → EGFR_p + PPARG_p	V(103) = K(103,1) * [EGFR_p \|PPARG];
R104	CASP9 + MAPK1_p	MAPK1_p \|CASP9	CASP9 + MAPK1_p → MAPK1_p \|CASP9	V(104) = K(104,1) * [MAPK1_p] * [CASP9] -K(104,2) * [MAPK1_p \|CASP9];
R105	MAPK1_p \|CASP9	CASP9_p + MAPK1_p	MAPK1_p \|CASP9 → CASP9_p + MAPK1_p	V(105) = K(105,1) * [MAPK1_p \|CASP9];
R106	JAK1_p + STAT6	JAK1_p \|STAT6	JAK1_p + STAT6 → JAK1_p \|STAT6	V(106) = K(106,1) * [JAK1_p] * [STAT6] -K(106,2) * [JAK1_p \|STAT6];
R107	JAK1_p \|STAT6	JAK1_p + STAT6_p	JAK1_p \|STAT6 → JAK1_p + STAT6_p	V(107) = K(107,1) * [JAK1_p \|STAT6];
R108	KIT_p + STAT1	KIT_p \|STAT1	KIT_p + STAT1 → KIT_p \|STAT1	V(108) = K(108,1) * [KIT_p] * [STAT1] -K(108,2) * [KIT_p \|STAT1];
R109	KIT_p \|STAT1	KIT_p + STAT1_p	KIT_p \|STAT1 → KIT_p + STAT1_p	V(109) = K(109,1) * [KIT_p \|STAT1];
R110	EP300 + PRKAA1	PRKAA1 \|EP300	EP300 + PRKAA1 → PRKAA1 \|EP300	V(110) = K(110,1) * [PRKAA1] * [EP300] -K(110,2) * [PRKAA1 \|EP300];
R111	PRKAA1 \|EP300	EP300_p + PRKAA1	PRKAA1 \|EP300 → EP300_p + PRKAA1	V(111) = K(111,1) * [PRKAA1 \|EP300];
R112	MAP4K2 + MAP4K2_p	MAP4K2_p \|MAP4K2	MAP4K2 + MAP4K2_p → MAP4K2_p \|MAP4K2	V(112) = K(112,1) * [MAP4K2_p] * [MAP4K2] -K(112,2) * [MAP4K2_p \|MAP4K2];
R113	MAP4K2_p \|MAP4K2	MAP4K2_p + MAP4K2_p	MAP4K2_p \|MAP4K2 → MAP4K2_p + MAP4K2_p	V(113) = K(113,1) * [MAP4K2_p \|MAP4K2];
R114	PRKAA1 + SREBF1	PRKAA1 \|SREBF1	PRKAA1 + SREBF1 → PRKAA1 \|SREBF1	V(114) = K(114,1) * [PRKAA1] * [SREBF1] -K(114,2) * [PRKAA1 \|SREBF1];
R115	PRKAA1 \|SREBF1	PRKAA1 + SREBF1_p	PRKAA1 \|SREBF1 → PRKAA1 + SREBF1_p	V(115) = K(115,1) * [PRKAA1 \|SREBF1];
R116	JUNB + MAPK8_p	MAPK8_p \|JUNB	JUNB + MAPK8_p → MAPK8_p \|JUNB	V(116) = K(116,1) * [MAPK8_p] * [JUNB] -K(116,2) * [MAPK8_p \|JUNB];
R117	MAPK8_p \|JUNB	JUNB_p + MAPK8_p	MAPK8_p \|JUNB → JUNB_p + MAPK8_p	V(117) = K(117,1) * [MAPK8_p \|JUNB];
R118	MAPK1 + MAPK1_p	MAPK1_p \|MAPK1	MAPK1 + MAPK1_p → MAPK1_p \|MAPK1	V(118) = K(118,1) * [MAPK1_p] * [MAPK1] -K(118,2) * [MAPK1_p \|MAPK1];
R119	MAPK1_p \|MAPK1	MAPK1_p + MAPK1_p	MAPK1_p \|MAPK1 → MAPK1_p + MAPK1_p	V(119) = K(119,1) * [MAPK1_p \|MAPK1];
R120	PRKAA1 + TSC2	PRKAA1 \|TSC2	PRKAA1 + TSC2 → PRKAA1 \|TSC2	V(120) = K(120,1) * [PRKAA1] * [TSC2] -K(120,2) * [PRKAA1 \|TSC2];
R121	PRKAA1 \|TSC2	PRKAA1 + TSC2_p	PRKAA1 \|TSC2 → PRKAA1 + TSC2_p	V(121) = K(121,1) * [PRKAA1 \|TSC2];
R122	LYN + LYN_p	LYN_p \|LYN	LYN + LYN_p → LYN_p \|LYN	V(122) = K(122,1) * [LYN_p] * [LYN] -K(122,2) * [LYN_p \|LYN];
R123	LYN_p \|LYN	LYN_p + LYN_p	LYN_p \|LYN → LYN_p + LYN_p	V(123) = K(123,1) * [LYN_p \|LYN];
R124	MAPK1_p + ZFP36	MAPK1_p \|ZFP36	MAPK1_p + ZFP36 → MAPK1_p \|ZFP36	V(124) = K(124,1) * [MAPK1_p] * [ZFP36] -K(124,2) * [MAPK1_p \|ZFP36];
R125	MAPK1_p \|ZFP36	MAPK1_p + ZFP36_p	MAPK1_p \|ZFP36 → MAPK1_p + ZFP36_p	V(125) = K(125,1) * [MAPK1_p \|ZFP36];
R126	HIPK2 + PRKAA1	PRKAA1 \|HIPK2	HIPK2 + PRKAA1 → PRKAA1 \|HIPK2	V(126) = K(126,1) * [PRKAA1] * [HIPK2] -K(126,2) * [PRKAA1 \|HIPK2];
R127	PRKAA1 \|HIPK2	HIPK2_p + PRKAA1	PRKAA1 \|HIPK2 → HIPK2_p + PRKAA1	V(127) = K(127,1) * [PRKAA1 \|HIPK2];
R128	MAPK8_p + SIGNOR-C154	MAPK8_p \|SIGNOR-C154	MAPK8_p + SIGNOR-C154 → MAPK8_p \|SIGNOR-C154	V(128) = K(128,1) * [MAPK8_p] * [SIGNOR-C154] -K(128,2) * [MAPK8_p \|SIGNOR-C154];
R129	MAPK8_p \|SIGNOR-C154	MAPK8_p + SIGNOR-C154_p	MAPK8_p \|SIGNOR-C154 → MAPK8_p + SIGNOR-C154_p	V(129) = K(129,1) * [MAPK8_p \|SIGNOR-C154];
R130	EP300 + HIPK2_p	HIPK2_p \|EP300	EP300 + HIPK2_p → HIPK2_p \|EP300	V(130) = K(130,1) * [HIPK2_p] * [EP300] -K(130,2) * [HIPK2_p \|EP300];
R131	HIPK2_p \|EP300	EP300_p + HIPK2_p	HIPK2_p \|EP300 → EP300_p + HIPK2_p	V(131) = K(131,1) * [HIPK2_p \|EP300];
R132	AR + MAPK1_p	MAPK1_p \|AR	AR + MAPK1_p → MAPK1_p \|AR	V(132) = K(132,1) * [MAPK1_p] * [AR] -K(132,2) * [MAPK1_p \|AR];
R133	MAPK1_p \|AR	AR_p + MAPK1_p	MAPK1_p \|AR → AR_p + MAPK1_p	V(133) = K(133,1) * [MAPK1_p \|AR];
R134	PKM_p + STAT3	PKM_p \|STAT3	PKM_p + STAT3 → PKM_p \|STAT3	V(134) = K(134,1) * [PKM_p] * [STAT3] -K(134,2) * [PKM_p \|STAT3];
R135	PKM_p \|STAT3	PKM_p + STAT3_p	PKM_p \|STAT3 → PKM_p + STAT3_p	V(135) = K(135,1) * [PKM_p \|STAT3];
R136	JAK1_p + PTPN11	JAK1_p \|PTPN11	JAK1_p + PTPN11 → JAK1_p \|PTPN11	V(136) = K(136,1) * [JAK1_p] * [PTPN11] -K(136,2) * [JAK1_p \|PTPN11];
R137	JAK1_p \|PTPN11	JAK1_p + PTPN11_p	JAK1_p \|PTPN11 → JAK1_p + PTPN11_p	V(137) = K(137,1) * [JAK1_p \|PTPN11];
R138	EGFR_p + STAT1	EGFR_p \|STAT1	EGFR_p + STAT1 → EGFR_p \|STAT1	V(138) = K(138,1) * [EGFR_p] * [STAT1] -K(138,2) * [EGFR_p \|STAT1];
R139	EGFR_p \|STAT1	EGFR_p + STAT1_p	EGFR_p \|STAT1 → EGFR_p + STAT1_p	V(139) = K(139,1) * [EGFR_p \|STAT1];
R140	MFF + PRKAA1	PRKAA1 \|MFF	MFF + PRKAA1 → PRKAA1 \|MFF	V(140) = K(140,1) * [PRKAA1] * [MFF] -K(140,2) * [PRKAA1 \|MFF];
R141	PRKAA1 \|MFF	MFF_p + PRKAA1	PRKAA1 \|MFF → MFF_p + PRKAA1	V(141) = K(141,1) * [PRKAA1 \|MFF];
R142	MAPK8_p + STAT3	MAPK8_p \|STAT3	MAPK8_p + STAT3 → MAPK8_p \|STAT3	V(142) = K(142,1) * [MAPK8_p] * [STAT3] -K(142,2) * [MAPK8_p \|STAT3];
R143	MAPK8_p \|STAT3	MAPK8_p + STAT3_p	MAPK8_p \|STAT3 → MAPK8_p + STAT3_p	V(143) = K(143,1) * [MAPK8_p \|STAT3];
R144	EGFR_p + PARP1	EGFR_p \|PARP1	EGFR_p + PARP1 → EGFR_p \|PARP1	V(144) = K(144,1) * [EGFR_p] * [PARP1] -K(144,2) * [EGFR_p \|PARP1];
R145	EGFR_p \|PARP1	EGFR_p + PARP1_p	EGFR_p \|PARP1 → EGFR_p + PARP1_p	V(145) = K(145,1) * [EGFR_p \|PARP1];
R146	KIT_p + SIGNOR-C156	KIT_p \|SIGNOR-C156	KIT_p + SIGNOR-C156 → KIT_p \|SIGNOR-C156	V(146) = K(146,1) * [KIT_p] * [SIGNOR-C156] -K(146,2) * [KIT_p \|SIGNOR-C156];
R147	KIT_p \|SIGNOR-C156	KIT_p + SIGNOR-C156_p	KIT_p \|SIGNOR-C156 → KIT_p + SIGNOR-C156_p	V(147) = K(147,1) * [KIT_p \|SIGNOR-C156];
R148	MAPK8_p + STAT1	MAPK8_p \|STAT1	MAPK8_p + STAT1 → MAPK8_p \|STAT1	V(148) = K(148,1) * [MAPK8_p] * [STAT1] -K(148,2) * [MAPK8_p \|STAT1];
R149	MAPK8_p \|STAT1	MAPK8_p + STAT1_p	MAPK8_p \|STAT1 → MAPK8_p + STAT1_p	V(149) = K(149,1) * [MAPK8_p \|STAT1];
R150	CDKN1B + LYN_p	LYN_p \|CDKN1B	CDKN1B + LYN_p → LYN_p \|CDKN1B	V(150) = K(150,1) * [LYN_p] * [CDKN1B] -K(150,2) * [LYN_p \|CDKN1B];
R151	LYN_p \|CDKN1B	CDKN1B_p + LYN_p	LYN_p \|CDKN1B → CDKN1B_p + LYN_p	V(151) = K(151,1) * [LYN_p \|CDKN1B];
R152	MAPK8_p + NR4A1	MAPK8_p \|NR4A1	MAPK8_p + NR4A1 → MAPK8_p \|NR4A1	V(152) = K(152,1) * [MAPK8_p] * [NR4A1] -K(152,2) * [MAPK8_p \|NR4A1];
R153	MAPK8_p \|NR4A1	MAPK8_p + NR4A1_p	MAPK8_p \|NR4A1 → MAPK8_p + NR4A1_p	V(153) = K(153,1) * [MAPK8_p \|NR4A1];
R154	ATR + CREB1	ATR \|CREB1	ATR + CREB1 → ATR \|CREB1	V(154) = K(154,1) * [ATR] * [CREB1] -K(154,2) * [ATR \|CREB1];
R155	ATR \|CREB1	ATR + CREB1_p	ATR \|CREB1 → ATR + CREB1_p	V(155) = K(155,1) * [ATR \|CREB1];
R156	AGO2 + EGFR_p	EGFR_p \|AGO2	AGO2 + EGFR_p → EGFR_p \|AGO2	V(156) = K(156,1) * [EGFR_p] * [AGO2] -K(156,2) * [EGFR_p \|AGO2];
R157	EGFR_p \|AGO2	AGO2_p + EGFR_p	EGFR_p \|AGO2 → AGO2_p + EGFR_p	V(157) = K(157,1) * [EGFR_p \|AGO2];
R158	EGFR_p + LYN	EGFR_p \|LYN	EGFR_p + LYN → EGFR_p \|LYN	V(158) = K(158,1) * [EGFR_p] * [LYN] -K(158,2) * [EGFR_p \|LYN];
R159	EGFR_p \|LYN	EGFR_p + LYN_p	EGFR_p \|LYN → EGFR_p + LYN_p	V(159) = K(159,1) * [EGFR_p \|LYN];
R160	ANXA1 + EGFR_p	EGFR_p \|ANXA1	ANXA1 + EGFR_p → EGFR_p \|ANXA1	V(160) = K(160,1) * [EGFR_p] * [ANXA1] -K(160,2) * [EGFR_p \|ANXA1];
R161	EGFR_p \|ANXA1	ANXA1_p + EGFR_p	EGFR_p \|ANXA1 → ANXA1_p + EGFR_p	V(161) = K(161,1) * [EGFR_p \|ANXA1];
R162	CTNNB1 + MAPK9_p	MAPK9_p \|CTNNB1	CTNNB1 + MAPK9_p → MAPK9_p \|CTNNB1	V(162) = K(162,1) * [MAPK9_p] * [CTNNB1] -K(162,2) * [MAPK9_p \|CTNNB1];
R163	MAPK9_p \|CTNNB1	CTNNB1_p + MAPK9_p	MAPK9_p \|CTNNB1 → CTNNB1_p + MAPK9_p	V(163) = K(163,1) * [MAPK9_p \|CTNNB1];
R164	EGFR_p + STAT3	EGFR_p \|STAT3	EGFR_p + STAT3 → EGFR_p \|STAT3	V(164) = K(164,1) * [EGFR_p] * [STAT3] -K(164,2) * [EGFR_p \|STAT3];
R165	EGFR_p \|STAT3	EGFR_p + STAT3_p	EGFR_p \|STAT3 → EGFR_p + STAT3_p	V(165) = K(165,1) * [EGFR_p \|STAT3];
R166	LYN_p + STAT3	LYN_p \|STAT3	LYN_p + STAT3 → LYN_p \|STAT3	V(166) = K(166,1) * [LYN_p] * [STAT3] -K(166,2) * [LYN_p \|STAT3];
R167	LYN_p \|STAT3	LYN_p + STAT3_p	LYN_p \|STAT3 → LYN_p + STAT3_p	V(167) = K(167,1) * [LYN_p \|STAT3];
R168	NFE2L2 + PRKAA1	PRKAA1 \|NFE2L2	NFE2L2 + PRKAA1 → PRKAA1 \|NFE2L2	V(168) = K(168,1) * [PRKAA1] * [NFE2L2] -K(168,2) * [PRKAA1 \|NFE2L2];
R169	PRKAA1 \|NFE2L2	NFE2L2_p + PRKAA1	PRKAA1 \|NFE2L2 → NFE2L2_p + PRKAA1	V(169) = K(169,1) * [PRKAA1 \|NFE2L2];
R170	CDKN1B + HIPK2_p	HIPK2_p \|CDKN1B	CDKN1B + HIPK2_p → HIPK2_p \|CDKN1B	V(170) = K(170,1) * [HIPK2_p] * [CDKN1B] -K(170,2) * [HIPK2_p \|CDKN1B];
R171	HIPK2_p \|CDKN1B	CDKN1B_p + HIPK2_p	HIPK2_p \|CDKN1B → CDKN1B_p + HIPK2_p	V(171) = K(171,1) * [HIPK2_p \|CDKN1B];
R172	PRKAA1 + PRKAA1	PRKAA1 \|PRKAA1	PRKAA1 + PRKAA1 → PRKAA1 \|PRKAA1	V(172) = K(172,1) * [PRKAA1] * [PRKAA1] -K(172,2) * [PRKAA1 \|PRKAA1];
R173	PRKAA1 \|PRKAA1	PRKAA1 + PRKAA1_p	PRKAA1 \|PRKAA1 → PRKAA1 + PRKAA1_p	V(173) = K(173,1) * [PRKAA1 \|PRKAA1];
R174	LEPR + STAT3	LEPR \|STAT3	LEPR + STAT3 → LEPR \|STAT3	V(174) = K(174,1) * [LEPR] * [STAT3] -K(174,2) * [LEPR \|STAT3];
R175	LEPR \|STAT3	LEPR + STAT3_p	LEPR \|STAT3 → LEPR + STAT3_p	V(175) = K(175,1) * [LEPR \|STAT3];
R176	LYN_p + SOCS1	LYN_p \|SOCS1	LYN_p + SOCS1 → LYN_p \|SOCS1	V(176) = K(176,1) * [LYN_p] * [SOCS1] -K(176,2) * [LYN_p \|SOCS1];
R177	LYN_p \|SOCS1	LYN_p + SOCS1_p	LYN_p \|SOCS1 → LYN_p + SOCS1_p	V(177) = K(177,1) * [LYN_p \|SOCS1];
R178	STAT1 + TEK_p	TEK_p \|STAT1	STAT1 + TEK_p → TEK_p \|STAT1	V(178) = K(178,1) * [TEK_p] * [STAT1] -K(178,2) * [TEK_p \|STAT1];
R179	TEK_p \|STAT1	STAT1_p + TEK_p	TEK_p \|STAT1 → STAT1_p + TEK_p	V(179) = K(179,1) * [TEK_p \|STAT1];
R180	EGFR + LYN_p	LYN_p \|EGFR	EGFR + LYN_p → LYN_p \|EGFR	V(180) = K(180,1) * [LYN_p] * [EGFR] -K(180,2) * [LYN_p \|EGFR];
R181	LYN_p \|EGFR	EGFR_p + LYN_p	LYN_p \|EGFR → EGFR_p + LYN_p	V(181) = K(181,1) * [LYN_p \|EGFR];
R182	CTNNB1 + EGFR_p	EGFR_p \|CTNNB1	CTNNB1 + EGFR_p → EGFR_p \|CTNNB1	V(182) = K(182,1) * [EGFR_p] * [CTNNB1] -K(182,2) * [EGFR_p \|CTNNB1];
R183	EGFR_p \|CTNNB1	CTNNB1_p + EGFR_p	EGFR_p \|CTNNB1 → CTNNB1_p + EGFR_p	V(183) = K(183,1) * [EGFR_p \|CTNNB1];
R184	EGFR_p + PTPN11	EGFR_p \|PTPN11	EGFR_p + PTPN11 → EGFR_p \|PTPN11	V(184) = K(184,1) * [EGFR_p] * [PTPN11] -K(184,2) * [EGFR_p \|PTPN11];
R185	EGFR_p \|PTPN11	EGFR_p + PTPN11_p	EGFR_p \|PTPN11 → EGFR_p + PTPN11_p	V(185) = K(185,1) * [EGFR_p \|PTPN11];
R186	HIPK2_p + MDM2	HIPK2_p \|MDM2	HIPK2_p + MDM2 → HIPK2_p \|MDM2	V(186) = K(186,1) * [HIPK2_p] * [MDM2] -K(186,2) * [HIPK2_p \|MDM2];
R187	HIPK2_p \|MDM2	HIPK2_p + MDM2_p	HIPK2_p \|MDM2 → HIPK2_p + MDM2_p	V(187) = K(187,1) * [HIPK2_p \|MDM2];
R188	EP300 + ROCK2	ROCK2 \|EP300	EP300 + ROCK2 → ROCK2 \|EP300	V(188) = K(188,1) * [ROCK2] * [EP300] -K(188,2) * [ROCK2 \|EP300];
R189	ROCK2 \|EP300	EP300_p + ROCK2	ROCK2 \|EP300 → EP300_p + ROCK2	V(189) = K(189,1) * [ROCK2 \|EP300];
R190	MAPK1_p + STAT3	MAPK1_p \|STAT3	MAPK1_p + STAT3 → MAPK1_p \|STAT3	V(190) = K(190,1) * [MAPK1_p] * [STAT3] -K(190,2) * [MAPK1_p \|STAT3];
R191	MAPK1_p \|STAT3	MAPK1_p + STAT3_p	MAPK1_p \|STAT3 → MAPK1_p + STAT3_p	V(191) = K(191,1) * [MAPK1_p \|STAT3];
R192	MAPK6 + MAPK6_p	MAPK6_p \|MAPK6	MAPK6 + MAPK6_p → MAPK6_p \|MAPK6	V(192) = K(192,1) * [MAPK6_p] * [MAPK6] -K(192,2) * [MAPK6_p \|MAPK6];
R193	MAPK6_p \|MAPK6	MAPK6_p + MAPK6_p	MAPK6_p \|MAPK6 → MAPK6_p + MAPK6_p	V(193) = K(193,1) * [MAPK6_p \|MAPK6];
R194	MAPK1_p + NR4A1	MAPK1_p \|NR4A1	MAPK1_p + NR4A1 → MAPK1_p \|NR4A1	V(194) = K(194,1) * [MAPK1_p] * [NR4A1] -K(194,2) * [MAPK1_p \|NR4A1];
R195	MAPK1_p \|NR4A1	MAPK1_p + NR4A1_p	MAPK1_p \|NR4A1 → MAPK1_p + NR4A1_p	V(195) = K(195,1) * [MAPK1_p \|NR4A1];
R196	ABCA1 + EGFR_p	EGFR_p \|ABCA1	ABCA1 + EGFR_p → EGFR_p \|ABCA1	V(196) = K(196,1) * [EGFR_p] * [ABCA1] -K(196,2) * [EGFR_p \|ABCA1];
R197	EGFR_p \|ABCA1	ABCA1_p + EGFR_p	EGFR_p \|ABCA1 → ABCA1_p + EGFR_p	V(197) = K(197,1) * [EGFR_p \|ABCA1];
R198	MAPK9_p + STAT3	MAPK9_p \|STAT3	MAPK9_p + STAT3 → MAPK9_p \|STAT3	V(198) = K(198,1) * [MAPK9_p] * [STAT3] -K(198,2) * [MAPK9_p \|STAT3];
R199	MAPK9_p \|STAT3	MAPK9_p + STAT3_p	MAPK9_p \|STAT3 → MAPK9_p + STAT3_p	V(199) = K(199,1) * [MAPK9_p \|STAT3];

Reaction ID	Reactants	Products	Original Text	ODE Equations
R1	SMAD2_p + SMAD4_p	SIGNOR-C8	SMAD2_p + SMAD4_p → SIGNOR-C8	V(1) = K(1,1) * [SMAD2_p] * [SMAD4_p] -K(1,2) * [SIGNOR-C8];
R2	JUN_p + SMAD4_p	SIGNOR-C10	JUN_p + SMAD4_p → SIGNOR-C10	V(2) = K(2,1) * [SMAD4_p] * [JUN_p] -K(2,2) * [SIGNOR-C10];
R3	SP1_p + STAT3_p	SIGNOR-C74	SP1_p + STAT3_p → SIGNOR-C74	V(3) = K(3,1) * [STAT3_p] * [SP1_p] -K(3,2) * [SIGNOR-C74];
R4	STAT1_p + STAT3_p	SIGNOR-C118	STAT1_p + STAT3_p → SIGNOR-C118	V(4) = K(4,1) * [STAT1_p] * [STAT3_p] -K(4,2) * [SIGNOR-C118];
R5	JAK1_p + SIGNOR-C118	SIGNOR-C120	JAK1_p + SIGNOR-C118 → SIGNOR-C120	V(5) = K(5,1) * [SIGNOR-C118] * [JAK1_p] -K(5,2) * [SIGNOR-C120];
R6	FOS_p + FOS_p + FOS_p + FOS_p + JUN_p + JUN_p + JUN_p + JUN_p	SIGNOR-C154	FOS_p + FOS_p + FOS_p + FOS_p + JUN_p + JUN_p + JUN_p + JUN_p → SIGNOR-C154	V(6) = K(6,1) * [FOS_p] * [JUN_p] * [JUN_p] * [FOS_p] * [JUN_p] * [FOS_p] * [FOS_p] * [JUN_p] -K(6,2) * [SIGNOR-C154];
R7	PIK3CA_u + PIK3R1_p	SIGNOR-C156	PIK3CA_u + PIK3R1_p → SIGNOR-C156	V(7) = K(7,1) * [PIK3R1_p] * [PIK3CA_u] -K(7,2) * [SIGNOR-C156];
R8	EP300 + MAPK1_p	MAPK1_p \|EP300	EP300 + MAPK1_p → MAPK1_p \|EP300	V(8) = K(8,1) * [MAPK1_p] * [EP300] -K(8,2) * [MAPK1_p \|EP300];
R9	MAPK1_p \|EP300	EP300_p + MAPK1_p	MAPK1_p \|EP300 → EP300_p + MAPK1_p	V(9) = K(9,1) * [MAPK1_p \|EP300];
R10	HIF1A + MAPK1_p	MAPK1_p \|HIF1A	HIF1A + MAPK1_p → MAPK1_p \|HIF1A	V(10) = K(10,1) * [MAPK1_p] * [HIF1A] -K(10,2) * [MAPK1_p \|HIF1A];
R11	MAPK1_p \|HIF1A	HIF1A_p + MAPK1_p	MAPK1_p \|HIF1A → HIF1A_p + MAPK1_p	V(11) = K(11,1) * [MAPK1_p \|HIF1A];
R12	MAPK1_p + NR3C1	MAPK1_p \|NR3C1	MAPK1_p + NR3C1 → MAPK1_p \|NR3C1	V(12) = K(12,1) * [MAPK1_p] * [NR3C1] -K(12,2) * [MAPK1_p \|NR3C1];
R13	MAPK1_p \|NR3C1	MAPK1_p + NR3C1_p	MAPK1_p \|NR3C1 → MAPK1_p + NR3C1_p	V(13) = K(13,1) * [MAPK1_p \|NR3C1];
R14	MAPK1_p + PRDX6	MAPK1_p \|PRDX6	MAPK1_p + PRDX6 → MAPK1_p \|PRDX6	V(14) = K(14,1) * [MAPK1_p] * [PRDX6] -K(14,2) * [MAPK1_p \|PRDX6];
R15	MAPK1_p \|PRDX6	MAPK1_p + PRDX6_p	MAPK1_p \|PRDX6 → MAPK1_p + PRDX6_p	V(15) = K(15,1) * [MAPK1_p \|PRDX6];
R16	KIT_p + PTPN11	KIT_p \|PTPN11	KIT_p + PTPN11 → KIT_p \|PTPN11	V(16) = K(16,1) * [KIT_p] * [PTPN11] -K(16,2) * [KIT_p \|PTPN11];
R17	KIT_p \|PTPN11	KIT_p + PTPN11_p	KIT_p \|PTPN11 → KIT_p + PTPN11_p	V(17) = K(17,1) * [KIT_p \|PTPN11];
R18	EGFR + EGFR_p	EGFR_p \|EGFR	EGFR + EGFR_p → EGFR_p \|EGFR	V(18) = K(18,1) * [EGFR_p] * [EGFR] -K(18,2) * [EGFR_p \|EGFR];
R19	EGFR_p \|EGFR	EGFR_p + EGFR_p	EGFR_p \|EGFR → EGFR_p + EGFR_p	V(19) = K(19,1) * [EGFR_p \|EGFR];
R20	CDKN1B + MAPK1_p	MAPK1_p \|CDKN1B	CDKN1B + MAPK1_p → MAPK1_p \|CDKN1B	V(20) = K(20,1) * [MAPK1_p] * [CDKN1B] -K(20,2) * [MAPK1_p \|CDKN1B];
R21	MAPK1_p \|CDKN1B	CDKN1B_p + MAPK1_p	MAPK1_p \|CDKN1B → CDKN1B_p + MAPK1_p	V(21) = K(21,1) * [MAPK1_p \|CDKN1B];
R22	MAPK1_p + SMAD4	MAPK1_p \|SMAD4	MAPK1_p + SMAD4 → MAPK1_p \|SMAD4	V(22) = K(22,1) * [MAPK1_p] * [SMAD4] -K(22,2) * [MAPK1_p \|SMAD4];
R23	MAPK1_p \|SMAD4	MAPK1_p + SMAD4_p	MAPK1_p \|SMAD4 → MAPK1_p + SMAD4_p	V(23) = K(23,1) * [MAPK1_p \|SMAD4];
R24	JUN + MAPK1_p	MAPK1_p \|JUN	JUN + MAPK1_p → MAPK1_p \|JUN	V(24) = K(24,1) * [MAPK1_p] * [JUN] -K(24,2) * [MAPK1_p \|JUN];
R25	MAPK1_p \|JUN	JUN_p + MAPK1_p	MAPK1_p \|JUN → JUN_p + MAPK1_p	V(25) = K(25,1) * [MAPK1_p \|JUN];
R26	FOS + MAPK1_p	MAPK1_p \|FOS	FOS + MAPK1_p → MAPK1_p \|FOS	V(26) = K(26,1) * [MAPK1_p] * [FOS] -K(26,2) * [MAPK1_p \|FOS];
R27	MAPK1_p \|FOS	FOS_p + MAPK1_p	MAPK1_p \|FOS → FOS_p + MAPK1_p	V(27) = K(27,1) * [MAPK1_p \|FOS];
R28	KDR + KDR_p	KDR_p \|KDR	KDR + KDR_p → KDR_p \|KDR	V(28) = K(28,1) * [KDR_p] * [KDR] -K(28,2) * [KDR_p \|KDR];
R29	KDR_p \|KDR	KDR_p + KDR_p	KDR_p \|KDR → KDR_p + KDR_p	V(29) = K(29,1) * [KDR_p \|KDR];
R30	BCL2 + MAPK8_p	MAPK8_p \|BCL2	BCL2 + MAPK8_p → MAPK8_p \|BCL2	V(30) = K(30,1) * [MAPK8_p] * [BCL2] -K(30,2) * [MAPK8_p \|BCL2];
R31	MAPK8_p \|BCL2	BCL2_p + MAPK8_p	MAPK8_p \|BCL2 → BCL2_p + MAPK8_p	V(31) = K(31,1) * [MAPK8_p \|BCL2];
R32	MAPK1_p + SMAD2	MAPK1_p \|SMAD2	MAPK1_p + SMAD2 → MAPK1_p \|SMAD2	V(32) = K(32,1) * [MAPK1_p] * [SMAD2] -K(32,2) * [MAPK1_p \|SMAD2];
R33	MAPK1_p \|SMAD2	MAPK1_p + SMAD2_p	MAPK1_p \|SMAD2 → MAPK1_p + SMAD2_p	V(33) = K(33,1) * [MAPK1_p \|SMAD2];
R34	CTNNB1 + KIT_p	KIT_p \|CTNNB1	CTNNB1 + KIT_p → KIT_p \|CTNNB1	V(34) = K(34,1) * [KIT_p] * [CTNNB1] -K(34,2) * [KIT_p \|CTNNB1];
R35	KIT_p \|CTNNB1	CTNNB1_p + KIT_p	KIT_p \|CTNNB1 → CTNNB1_p + KIT_p	V(35) = K(35,1) * [KIT_p \|CTNNB1];
R36	MAPK1_p + RORA	MAPK1_p \|RORA	MAPK1_p + RORA → MAPK1_p \|RORA	V(36) = K(36,1) * [MAPK1_p] * [RORA] -K(36,2) * [MAPK1_p \|RORA];
R37	MAPK1_p \|RORA	MAPK1_p + RORA_p	MAPK1_p \|RORA → MAPK1_p + RORA_p	V(37) = K(37,1) * [MAPK1_p \|RORA];
R38	JUN + MAPK9_p	MAPK9_p \|JUN	JUN + MAPK9_p → MAPK9_p \|JUN	V(38) = K(38,1) * [MAPK9_p] * [JUN] -K(38,2) * [MAPK9_p \|JUN];
R39	MAPK9_p \|JUN	JUN_p + MAPK9_p	MAPK9_p \|JUN → JUN_p + MAPK9_p	V(39) = K(39,1) * [MAPK9_p \|JUN];
R40	BCL2 + MAPK1_p	MAPK1_p \|BCL2	BCL2 + MAPK1_p → MAPK1_p \|BCL2	V(40) = K(40,1) * [MAPK1_p] * [BCL2] -K(40,2) * [MAPK1_p \|BCL2];
R41	MAPK1_p \|BCL2	BCL2_p + MAPK1_p	MAPK1_p \|BCL2 → BCL2_p + MAPK1_p	V(41) = K(41,1) * [MAPK1_p \|BCL2];
R42	MAPK1_p + SREBF1	MAPK1_p \|SREBF1	MAPK1_p + SREBF1 → MAPK1_p \|SREBF1	V(42) = K(42,1) * [MAPK1_p] * [SREBF1] -K(42,2) * [MAPK1_p \|SREBF1];
R43	MAPK1_p \|SREBF1	MAPK1_p + SREBF1_p	MAPK1_p \|SREBF1 → MAPK1_p + SREBF1_p	V(43) = K(43,1) * [MAPK1_p \|SREBF1];
R44	JAK1_p + STAT1	JAK1_p \|STAT1	JAK1_p + STAT1 → JAK1_p \|STAT1	V(44) = K(44,1) * [JAK1_p] * [STAT1] -K(44,2) * [JAK1_p \|STAT1];
R45	JAK1_p \|STAT1	JAK1_p + STAT1_p	JAK1_p \|STAT1 → JAK1_p + STAT1_p	V(45) = K(45,1) * [JAK1_p \|STAT1];
R46	DUSP1 + MAPK1_p	MAPK1_p \|DUSP1	DUSP1 + MAPK1_p → MAPK1_p \|DUSP1	V(46) = K(46,1) * [MAPK1_p] * [DUSP1] -K(46,2) * [MAPK1_p \|DUSP1];
R47	MAPK1_p \|DUSP1	DUSP1_p + MAPK1_p	MAPK1_p \|DUSP1 → DUSP1_p + MAPK1_p	V(47) = K(47,1) * [MAPK1_p \|DUSP1];
R48	MAPK1_p + NR3C2	MAPK1_p \|NR3C2	MAPK1_p + NR3C2 → MAPK1_p \|NR3C2	V(48) = K(48,1) * [MAPK1_p] * [NR3C2] -K(48,2) * [MAPK1_p \|NR3C2];
R49	MAPK1_p \|NR3C2	MAPK1_p + NR3C2_p	MAPK1_p \|NR3C2 → MAPK1_p + NR3C2_p	V(49) = K(49,1) * [MAPK1_p \|NR3C2];
R50	MAPK8_p + MAPK9	MAPK8_p \|MAPK9	MAPK8_p + MAPK9 → MAPK8_p \|MAPK9	V(50) = K(50,1) * [MAPK8_p] * [MAPK9] -K(50,2) * [MAPK8_p \|MAPK9];
R51	MAPK8_p \|MAPK9	MAPK8_p + MAPK9_p	MAPK8_p \|MAPK9 → MAPK8_p + MAPK9_p	V(51) = K(51,1) * [MAPK8_p \|MAPK9];
R52	MAPK1_p + TSC2	MAPK1_p \|TSC2	MAPK1_p + TSC2 → MAPK1_p \|TSC2	V(52) = K(52,1) * [MAPK1_p] * [TSC2] -K(52,2) * [MAPK1_p \|TSC2];
R53	MAPK1_p \|TSC2	MAPK1_p + TSC2_p	MAPK1_p \|TSC2 → MAPK1_p + TSC2_p	V(53) = K(53,1) * [MAPK1_p \|TSC2];
R54	KIT + KIT_p	KIT_p \|KIT	KIT + KIT_p → KIT_p \|KIT	V(54) = K(54,1) * [KIT_p] * [KIT] -K(54,2) * [KIT_p \|KIT];
R55	KIT_p \|KIT	KIT_p + KIT_p	KIT_p \|KIT → KIT_p + KIT_p	V(55) = K(55,1) * [KIT_p \|KIT];
R56	MAPK1_p + RHOA	MAPK1_p \|RHOA	MAPK1_p + RHOA → MAPK1_p \|RHOA	V(56) = K(56,1) * [MAPK1_p] * [RHOA] -K(56,2) * [MAPK1_p \|RHOA];
R57	MAPK1_p \|RHOA	MAPK1_p + RHOA_p	MAPK1_p \|RHOA → MAPK1_p + RHOA_p	V(57) = K(57,1) * [MAPK1_p \|RHOA];
R58	ATR + PARP1	ATR \|PARP1	ATR + PARP1 → ATR \|PARP1	V(58) = K(58,1) * [ATR] * [PARP1] -K(58,2) * [ATR \|PARP1];
R59	ATR \|PARP1	ATR + PARP1_p	ATR \|PARP1 → ATR + PARP1_p	V(59) = K(59,1) * [ATR \|PARP1];
R60	MAPK8_p + NR3C1	MAPK8_p \|NR3C1	MAPK8_p + NR3C1 → MAPK8_p \|NR3C1	V(60) = K(60,1) * [MAPK8_p] * [NR3C1] -K(60,2) * [MAPK8_p \|NR3C1];
R61	MAPK8_p \|NR3C1	MAPK8_p + NR3C1_p	MAPK8_p \|NR3C1 → MAPK8_p + NR3C1_p	V(61) = K(61,1) * [MAPK8_p \|NR3C1];
R62	MAPK1_p + PPARG	MAPK1_p \|PPARG	MAPK1_p + PPARG → MAPK1_p \|PPARG	V(62) = K(62,1) * [MAPK1_p] * [PPARG] -K(62,2) * [MAPK1_p \|PPARG];
R63	MAPK1_p \|PPARG	MAPK1_p + PPARG_p	MAPK1_p \|PPARG → MAPK1_p + PPARG_p	V(63) = K(63,1) * [MAPK1_p \|PPARG];
R64	MAPK1_p + TFEB	MAPK1_p \|TFEB	MAPK1_p + TFEB → MAPK1_p \|TFEB	V(64) = K(64,1) * [MAPK1_p] * [TFEB] -K(64,2) * [MAPK1_p \|TFEB];
R65	MAPK1_p \|TFEB	MAPK1_p + TFEB_p	MAPK1_p \|TFEB → MAPK1_p + TFEB_p	V(65) = K(65,1) * [MAPK1_p \|TFEB];
R66	ATR + MDM2	ATR \|MDM2	ATR + MDM2 → ATR \|MDM2	V(66) = K(66,1) * [ATR] * [MDM2] -K(66,2) * [ATR \|MDM2];
R67	ATR \|MDM2	ATR + MDM2_p	ATR \|MDM2 → ATR + MDM2_p	V(67) = K(67,1) * [ATR \|MDM2];
R68	MAPK1_p + SIGNOR-C154	MAPK1_p \|SIGNOR-C154	MAPK1_p + SIGNOR-C154 → MAPK1_p \|SIGNOR-C154	V(68) = K(68,1) * [MAPK1_p] * [SIGNOR-C154] -K(68,2) * [MAPK1_p \|SIGNOR-C154];
R69	MAPK1_p \|SIGNOR-C154	MAPK1_p + SIGNOR-C154_p	MAPK1_p \|SIGNOR-C154 → MAPK1_p + SIGNOR-C154_p	V(69) = K(69,1) * [MAPK1_p \|SIGNOR-C154];
R70	CTNNB1 + MAPK8_p	MAPK8_p \|CTNNB1	CTNNB1 + MAPK8_p → MAPK8_p \|CTNNB1	V(70) = K(70,1) * [MAPK8_p] * [CTNNB1] -K(70,2) * [MAPK8_p \|CTNNB1];
R71	MAPK8_p \|CTNNB1	CTNNB1_p + MAPK8_p	MAPK8_p \|CTNNB1 → CTNNB1_p + MAPK8_p	V(71) = K(71,1) * [MAPK8_p \|CTNNB1];
R72	HIPK2 + HIPK2_p	HIPK2_p \|HIPK2	HIPK2 + HIPK2_p → HIPK2_p \|HIPK2	V(72) = K(72,1) * [HIPK2_p] * [HIPK2] -K(72,2) * [HIPK2_p \|HIPK2];
R73	HIPK2_p \|HIPK2	HIPK2_p + HIPK2_p	HIPK2_p \|HIPK2 → HIPK2_p + HIPK2_p	V(73) = K(73,1) * [HIPK2_p \|HIPK2];
R74	MAPK8_p + PKM	MAPK8_p \|PKM	MAPK8_p + PKM → MAPK8_p \|PKM	V(74) = K(74,1) * [MAPK8_p] * [PKM] -K(74,2) * [MAPK8_p \|PKM];
R75	MAPK8_p \|PKM	MAPK8_p + PKM_p	MAPK8_p \|PKM → MAPK8_p + PKM_p	V(75) = K(75,1) * [MAPK8_p \|PKM];
R76	EGFR + MAPK1_p	MAPK1_p \|EGFR	EGFR + MAPK1_p → MAPK1_p \|EGFR	V(76) = K(76,1) * [MAPK1_p] * [EGFR] -K(76,2) * [MAPK1_p \|EGFR];
R77	MAPK1_p \|EGFR	EGFR_p + MAPK1_p	MAPK1_p \|EGFR → EGFR_p + MAPK1_p	V(77) = K(77,1) * [MAPK1_p \|EGFR];
R78	MAPK8_p + STAT6	MAPK8_p \|STAT6	MAPK8_p + STAT6 → MAPK8_p \|STAT6	V(78) = K(78,1) * [MAPK8_p] * [STAT6] -K(78,2) * [MAPK8_p \|STAT6];
R79	MAPK8_p \|STAT6	MAPK8_p + STAT6_p	MAPK8_p \|STAT6 → MAPK8_p + STAT6_p	V(79) = K(79,1) * [MAPK8_p \|STAT6];
R80	DNMT1 + PRKAA1	PRKAA1 \|DNMT1	DNMT1 + PRKAA1 → PRKAA1 \|DNMT1	V(80) = K(80,1) * [PRKAA1] * [DNMT1] -K(80,2) * [PRKAA1 \|DNMT1];
R81	PRKAA1 \|DNMT1	DNMT1_p + PRKAA1	PRKAA1 \|DNMT1 → DNMT1_p + PRKAA1	V(81) = K(81,1) * [PRKAA1 \|DNMT1];
R82	TEK + TEK_p	TEK_p \|TEK	TEK + TEK_p → TEK_p \|TEK	V(82) = K(82,1) * [TEK_p] * [TEK] -K(82,2) * [TEK_p \|TEK];
R83	TEK_p \|TEK	TEK_p + TEK_p	TEK_p \|TEK → TEK_p + TEK_p	V(83) = K(83,1) * [TEK_p \|TEK];
R84	MAPK8_p + PPARG	MAPK8_p \|PPARG	MAPK8_p + PPARG → MAPK8_p \|PPARG	V(84) = K(84,1) * [MAPK8_p] * [PPARG] -K(84,2) * [MAPK8_p \|PPARG];
R85	MAPK8_p \|PPARG	MAPK8_p + PPARG_p	MAPK8_p \|PPARG → MAPK8_p + PPARG_p	V(85) = K(85,1) * [MAPK8_p \|PPARG];
R86	MAPK1_p + SP1	MAPK1_p \|SP1	MAPK1_p + SP1 → MAPK1_p \|SP1	V(86) = K(86,1) * [MAPK1_p] * [SP1] -K(86,2) * [MAPK1_p \|SP1];
R87	MAPK1_p \|SP1	MAPK1_p + SP1_p	MAPK1_p \|SP1 → MAPK1_p + SP1_p	V(87) = K(87,1) * [MAPK1_p \|SP1];
R88	CDKN1A + MAPK8_p	MAPK8_p \|CDKN1A	CDKN1A + MAPK8_p → MAPK8_p \|CDKN1A	V(88) = K(88,1) * [MAPK8_p] * [CDKN1A] -K(88,2) * [MAPK8_p \|CDKN1A];
R89	MAPK8_p \|CDKN1A	CDKN1A_p + MAPK8_p	MAPK8_p \|CDKN1A → CDKN1A_p + MAPK8_p	V(89) = K(89,1) * [MAPK8_p \|CDKN1A];
R90	CDKN1A + MAPK1_p	MAPK1_p \|CDKN1A	CDKN1A + MAPK1_p → MAPK1_p \|CDKN1A	V(90) = K(90,1) * [MAPK1_p] * [CDKN1A] -K(90,2) * [MAPK1_p \|CDKN1A];
R91	MAPK1_p \|CDKN1A	CDKN1A_p + MAPK1_p	MAPK1_p \|CDKN1A → CDKN1A_p + MAPK1_p	V(91) = K(91,1) * [MAPK1_p \|CDKN1A];
R92	JUN + MAPK8_p	MAPK8_p \|JUN	JUN + MAPK8_p → MAPK8_p \|JUN	V(92) = K(92,1) * [MAPK8_p] * [JUN] -K(92,2) * [MAPK8_p \|JUN];
R93	MAPK8_p \|JUN	JUN_p + MAPK8_p	MAPK8_p \|JUN → JUN_p + MAPK8_p	V(93) = K(93,1) * [MAPK8_p \|JUN];
R94	JAK1_p + STAT3	JAK1_p \|STAT3	JAK1_p + STAT3 → JAK1_p \|STAT3	V(94) = K(94,1) * [JAK1_p] * [STAT3] -K(94,2) * [JAK1_p \|STAT3];
R95	JAK1_p \|STAT3	JAK1_p + STAT3_p	JAK1_p \|STAT3 → JAK1_p + STAT3_p	V(95) = K(95,1) * [JAK1_p \|STAT3];
R96	MAPK1_p + PARP1	MAPK1_p \|PARP1	MAPK1_p + PARP1 → MAPK1_p \|PARP1	V(96) = K(96,1) * [MAPK1_p] * [PARP1] -K(96,2) * [MAPK1_p \|PARP1];
R97	MAPK1_p \|PARP1	MAPK1_p + PARP1_p	MAPK1_p \|PARP1 → MAPK1_p + PARP1_p	V(97) = K(97,1) * [MAPK1_p \|PARP1];
R98	EGFR_p + SIGNOR-C120	EGFR_p \|SIGNOR-C120	EGFR_p + SIGNOR-C120 → EGFR_p \|SIGNOR-C120	V(98) = K(98,1) * [EGFR_p] * [SIGNOR-C120] -K(98,2) * [EGFR_p \|SIGNOR-C120];
R99	EGFR_p \|SIGNOR-C120	EGFR_p + SIGNOR-C120_p	EGFR_p \|SIGNOR-C120 → EGFR_p + SIGNOR-C120_p	V(99) = K(99,1) * [EGFR_p \|SIGNOR-C120];
R100	MAPK8_p + SP1	MAPK8_p \|SP1	MAPK8_p + SP1 → MAPK8_p \|SP1	V(100) = K(100,1) * [MAPK8_p] * [SP1] -K(100,2) * [MAPK8_p \|SP1];
R101	MAPK8_p \|SP1	MAPK8_p + SP1_p	MAPK8_p \|SP1 → MAPK8_p + SP1_p	V(101) = K(101,1) * [MAPK8_p \|SP1];
R102	EGFR_p + PPARG	EGFR_p \|PPARG	EGFR_p + PPARG → EGFR_p \|PPARG	V(102) = K(102,1) * [EGFR_p] * [PPARG] -K(102,2) * [EGFR_p \|PPARG];
R103	EGFR_p \|PPARG	EGFR_p + PPARG_p	EGFR_p \|PPARG → EGFR_p + PPARG_p	V(103) = K(103,1) * [EGFR_p \|PPARG];
R104	CASP9 + MAPK1_p	MAPK1_p \|CASP9	CASP9 + MAPK1_p → MAPK1_p \|CASP9	V(104) = K(104,1) * [MAPK1_p] * [CASP9] -K(104,2) * [MAPK1_p \|CASP9];
R105	MAPK1_p \|CASP9	CASP9_p + MAPK1_p	MAPK1_p \|CASP9 → CASP9_p + MAPK1_p	V(105) = K(105,1) * [MAPK1_p \|CASP9];
R106	JAK1_p + STAT6	JAK1_p \|STAT6	JAK1_p + STAT6 → JAK1_p \|STAT6	V(106) = K(106,1) * [JAK1_p] * [STAT6] -K(106,2) * [JAK1_p \|STAT6];
R107	JAK1_p \|STAT6	JAK1_p + STAT6_p	JAK1_p \|STAT6 → JAK1_p + STAT6_p	V(107) = K(107,1) * [JAK1_p \|STAT6];
R108	KIT_p + STAT1	KIT_p \|STAT1	KIT_p + STAT1 → KIT_p \|STAT1	V(108) = K(108,1) * [KIT_p] * [STAT1] -K(108,2) * [KIT_p \|STAT1];
R109	KIT_p \|STAT1	KIT_p + STAT1_p	KIT_p \|STAT1 → KIT_p + STAT1_p	V(109) = K(109,1) * [KIT_p \|STAT1];
R110	EP300 + PRKAA1	PRKAA1 \|EP300	EP300 + PRKAA1 → PRKAA1 \|EP300	V(110) = K(110,1) * [PRKAA1] * [EP300] -K(110,2) * [PRKAA1 \|EP300];
R111	PRKAA1 \|EP300	EP300_p + PRKAA1	PRKAA1 \|EP300 → EP300_p + PRKAA1	V(111) = K(111,1) * [PRKAA1 \|EP300];
R112	MAP4K2 + MAP4K2_p	MAP4K2_p \|MAP4K2	MAP4K2 + MAP4K2_p → MAP4K2_p \|MAP4K2	V(112) = K(112,1) * [MAP4K2_p] * [MAP4K2] -K(112,2) * [MAP4K2_p \|MAP4K2];
R113	MAP4K2_p \|MAP4K2	MAP4K2_p + MAP4K2_p	MAP4K2_p \|MAP4K2 → MAP4K2_p + MAP4K2_p	V(113) = K(113,1) * [MAP4K2_p \|MAP4K2];
R114	PRKAA1 + SREBF1	PRKAA1 \|SREBF1	PRKAA1 + SREBF1 → PRKAA1 \|SREBF1	V(114) = K(114,1) * [PRKAA1] * [SREBF1] -K(114,2) * [PRKAA1 \|SREBF1];
R115	PRKAA1 \|SREBF1	PRKAA1 + SREBF1_p	PRKAA1 \|SREBF1 → PRKAA1 + SREBF1_p	V(115) = K(115,1) * [PRKAA1 \|SREBF1];
R116	JUNB + MAPK8_p	MAPK8_p \|JUNB	JUNB + MAPK8_p → MAPK8_p \|JUNB	V(116) = K(116,1) * [MAPK8_p] * [JUNB] -K(116,2) * [MAPK8_p \|JUNB];
R117	MAPK8_p \|JUNB	JUNB_p + MAPK8_p	MAPK8_p \|JUNB → JUNB_p + MAPK8_p	V(117) = K(117,1) * [MAPK8_p \|JUNB];
R118	MAPK1 + MAPK1_p	MAPK1_p \|MAPK1	MAPK1 + MAPK1_p → MAPK1_p \|MAPK1	V(118) = K(118,1) * [MAPK1_p] * [MAPK1] -K(118,2) * [MAPK1_p \|MAPK1];
R119	MAPK1_p \|MAPK1	MAPK1_p + MAPK1_p	MAPK1_p \|MAPK1 → MAPK1_p + MAPK1_p	V(119) = K(119,1) * [MAPK1_p \|MAPK1];
R120	PRKAA1 + TSC2	PRKAA1 \|TSC2	PRKAA1 + TSC2 → PRKAA1 \|TSC2	V(120) = K(120,1) * [PRKAA1] * [TSC2] -K(120,2) * [PRKAA1 \|TSC2];
R121	PRKAA1 \|TSC2	PRKAA1 + TSC2_p	PRKAA1 \|TSC2 → PRKAA1 + TSC2_p	V(121) = K(121,1) * [PRKAA1 \|TSC2];
R122	LYN + LYN_p	LYN_p \|LYN	LYN + LYN_p → LYN_p \|LYN	V(122) = K(122,1) * [LYN_p] * [LYN] -K(122,2) * [LYN_p \|LYN];
R123	LYN_p \|LYN	LYN_p + LYN_p	LYN_p \|LYN → LYN_p + LYN_p	V(123) = K(123,1) * [LYN_p \|LYN];
R124	MAPK1_p + ZFP36	MAPK1_p \|ZFP36	MAPK1_p + ZFP36 → MAPK1_p \|ZFP36	V(124) = K(124,1) * [MAPK1_p] * [ZFP36] -K(124,2) * [MAPK1_p \|ZFP36];
R125	MAPK1_p \|ZFP36	MAPK1_p + ZFP36_p	MAPK1_p \|ZFP36 → MAPK1_p + ZFP36_p	V(125) = K(125,1) * [MAPK1_p \|ZFP36];
R126	HIPK2 + PRKAA1	PRKAA1 \|HIPK2	HIPK2 + PRKAA1 → PRKAA1 \|HIPK2	V(126) = K(126,1) * [PRKAA1] * [HIPK2] -K(126,2) * [PRKAA1 \|HIPK2];
R127	PRKAA1 \|HIPK2	HIPK2_p + PRKAA1	PRKAA1 \|HIPK2 → HIPK2_p + PRKAA1	V(127) = K(127,1) * [PRKAA1 \|HIPK2];
R128	MAPK8_p + SIGNOR-C154	MAPK8_p \|SIGNOR-C154	MAPK8_p + SIGNOR-C154 → MAPK8_p \|SIGNOR-C154	V(128) = K(128,1) * [MAPK8_p] * [SIGNOR-C154] -K(128,2) * [MAPK8_p \|SIGNOR-C154];
R129	MAPK8_p \|SIGNOR-C154	MAPK8_p + SIGNOR-C154_p	MAPK8_p \|SIGNOR-C154 → MAPK8_p + SIGNOR-C154_p	V(129) = K(129,1) * [MAPK8_p \|SIGNOR-C154];
R130	EP300 + HIPK2_p	HIPK2_p \|EP300	EP300 + HIPK2_p → HIPK2_p \|EP300	V(130) = K(130,1) * [HIPK2_p] * [EP300] -K(130,2) * [HIPK2_p \|EP300];
R131	HIPK2_p \|EP300	EP300_p + HIPK2_p	HIPK2_p \|EP300 → EP300_p + HIPK2_p	V(131) = K(131,1) * [HIPK2_p \|EP300];
R132	AR + MAPK1_p	MAPK1_p \|AR	AR + MAPK1_p → MAPK1_p \|AR	V(132) = K(132,1) * [MAPK1_p] * [AR] -K(132,2) * [MAPK1_p \|AR];
R133	MAPK1_p \|AR	AR_p + MAPK1_p	MAPK1_p \|AR → AR_p + MAPK1_p	V(133) = K(133,1) * [MAPK1_p \|AR];
R134	PKM_p + STAT3	PKM_p \|STAT3	PKM_p + STAT3 → PKM_p \|STAT3	V(134) = K(134,1) * [PKM_p] * [STAT3] -K(134,2) * [PKM_p \|STAT3];
R135	PKM_p \|STAT3	PKM_p + STAT3_p	PKM_p \|STAT3 → PKM_p + STAT3_p	V(135) = K(135,1) * [PKM_p \|STAT3];
R136	JAK1_p + PTPN11	JAK1_p \|PTPN11	JAK1_p + PTPN11 → JAK1_p \|PTPN11	V(136) = K(136,1) * [JAK1_p] * [PTPN11] -K(136,2) * [JAK1_p \|PTPN11];
R137	JAK1_p \|PTPN11	JAK1_p + PTPN11_p	JAK1_p \|PTPN11 → JAK1_p + PTPN11_p	V(137) = K(137,1) * [JAK1_p \|PTPN11];
R138	EGFR_p + STAT1	EGFR_p \|STAT1	EGFR_p + STAT1 → EGFR_p \|STAT1	V(138) = K(138,1) * [EGFR_p] * [STAT1] -K(138,2) * [EGFR_p \|STAT1];
R139	EGFR_p \|STAT1	EGFR_p + STAT1_p	EGFR_p \|STAT1 → EGFR_p + STAT1_p	V(139) = K(139,1) * [EGFR_p \|STAT1];
R140	MFF + PRKAA1	PRKAA1 \|MFF	MFF + PRKAA1 → PRKAA1 \|MFF	V(140) = K(140,1) * [PRKAA1] * [MFF] -K(140,2) * [PRKAA1 \|MFF];
R141	PRKAA1 \|MFF	MFF_p + PRKAA1	PRKAA1 \|MFF → MFF_p + PRKAA1	V(141) = K(141,1) * [PRKAA1 \|MFF];
R142	MAPK8_p + STAT3	MAPK8_p \|STAT3	MAPK8_p + STAT3 → MAPK8_p \|STAT3	V(142) = K(142,1) * [MAPK8_p] * [STAT3] -K(142,2) * [MAPK8_p \|STAT3];
R143	MAPK8_p \|STAT3	MAPK8_p + STAT3_p	MAPK8_p \|STAT3 → MAPK8_p + STAT3_p	V(143) = K(143,1) * [MAPK8_p \|STAT3];
R144	EGFR_p + PARP1	EGFR_p \|PARP1	EGFR_p + PARP1 → EGFR_p \|PARP1	V(144) = K(144,1) * [EGFR_p] * [PARP1] -K(144,2) * [EGFR_p \|PARP1];
R145	EGFR_p \|PARP1	EGFR_p + PARP1_p	EGFR_p \|PARP1 → EGFR_p + PARP1_p	V(145) = K(145,1) * [EGFR_p \|PARP1];
R146	KIT_p + SIGNOR-C156	KIT_p \|SIGNOR-C156	KIT_p + SIGNOR-C156 → KIT_p \|SIGNOR-C156	V(146) = K(146,1) * [KIT_p] * [SIGNOR-C156] -K(146,2) * [KIT_p \|SIGNOR-C156];
R147	KIT_p \|SIGNOR-C156	KIT_p + SIGNOR-C156_p	KIT_p \|SIGNOR-C156 → KIT_p + SIGNOR-C156_p	V(147) = K(147,1) * [KIT_p \|SIGNOR-C156];
R148	MAPK8_p + STAT1	MAPK8_p \|STAT1	MAPK8_p + STAT1 → MAPK8_p \|STAT1	V(148) = K(148,1) * [MAPK8_p] * [STAT1] -K(148,2) * [MAPK8_p \|STAT1];
R149	MAPK8_p \|STAT1	MAPK8_p + STAT1_p	MAPK8_p \|STAT1 → MAPK8_p + STAT1_p	V(149) = K(149,1) * [MAPK8_p \|STAT1];
R150	CDKN1B + LYN_p	LYN_p \|CDKN1B	CDKN1B + LYN_p → LYN_p \|CDKN1B	V(150) = K(150,1) * [LYN_p] * [CDKN1B] -K(150,2) * [LYN_p \|CDKN1B];
R151	LYN_p \|CDKN1B	CDKN1B_p + LYN_p	LYN_p \|CDKN1B → CDKN1B_p + LYN_p	V(151) = K(151,1) * [LYN_p \|CDKN1B];
R152	MAPK8_p + NR4A1	MAPK8_p \|NR4A1	MAPK8_p + NR4A1 → MAPK8_p \|NR4A1	V(152) = K(152,1) * [MAPK8_p] * [NR4A1] -K(152,2) * [MAPK8_p \|NR4A1];
R153	MAPK8_p \|NR4A1	MAPK8_p + NR4A1_p	MAPK8_p \|NR4A1 → MAPK8_p + NR4A1_p	V(153) = K(153,1) * [MAPK8_p \|NR4A1];
R154	ATR + CREB1	ATR \|CREB1	ATR + CREB1 → ATR \|CREB1	V(154) = K(154,1) * [ATR] * [CREB1] -K(154,2) * [ATR \|CREB1];
R155	ATR \|CREB1	ATR + CREB1_p	ATR \|CREB1 → ATR + CREB1_p	V(155) = K(155,1) * [ATR \|CREB1];
R156	AGO2 + EGFR_p	EGFR_p \|AGO2	AGO2 + EGFR_p → EGFR_p \|AGO2	V(156) = K(156,1) * [EGFR_p] * [AGO2] -K(156,2) * [EGFR_p \|AGO2];
R157	EGFR_p \|AGO2	AGO2_p + EGFR_p	EGFR_p \|AGO2 → AGO2_p + EGFR_p	V(157) = K(157,1) * [EGFR_p \|AGO2];
R158	EGFR_p + LYN	EGFR_p \|LYN	EGFR_p + LYN → EGFR_p \|LYN	V(158) = K(158,1) * [EGFR_p] * [LYN] -K(158,2) * [EGFR_p \|LYN];
R159	EGFR_p \|LYN	EGFR_p + LYN_p	EGFR_p \|LYN → EGFR_p + LYN_p	V(159) = K(159,1) * [EGFR_p \|LYN];
R160	ANXA1 + EGFR_p	EGFR_p \|ANXA1	ANXA1 + EGFR_p → EGFR_p \|ANXA1	V(160) = K(160,1) * [EGFR_p] * [ANXA1] -K(160,2) * [EGFR_p \|ANXA1];
R161	EGFR_p \|ANXA1	ANXA1_p + EGFR_p	EGFR_p \|ANXA1 → ANXA1_p + EGFR_p	V(161) = K(161,1) * [EGFR_p \|ANXA1];
R162	CTNNB1 + MAPK9_p	MAPK9_p \|CTNNB1	CTNNB1 + MAPK9_p → MAPK9_p \|CTNNB1	V(162) = K(162,1) * [MAPK9_p] * [CTNNB1] -K(162,2) * [MAPK9_p \|CTNNB1];
R163	MAPK9_p \|CTNNB1	CTNNB1_p + MAPK9_p	MAPK9_p \|CTNNB1 → CTNNB1_p + MAPK9_p	V(163) = K(163,1) * [MAPK9_p \|CTNNB1];
R164	EGFR_p + STAT3	EGFR_p \|STAT3	EGFR_p + STAT3 → EGFR_p \|STAT3	V(164) = K(164,1) * [EGFR_p] * [STAT3] -K(164,2) * [EGFR_p \|STAT3];
R165	EGFR_p \|STAT3	EGFR_p + STAT3_p	EGFR_p \|STAT3 → EGFR_p + STAT3_p	V(165) = K(165,1) * [EGFR_p \|STAT3];
R166	LYN_p + STAT3	LYN_p \|STAT3	LYN_p + STAT3 → LYN_p \|STAT3	V(166) = K(166,1) * [LYN_p] * [STAT3] -K(166,2) * [LYN_p \|STAT3];
R167	LYN_p \|STAT3	LYN_p + STAT3_p	LYN_p \|STAT3 → LYN_p + STAT3_p	V(167) = K(167,1) * [LYN_p \|STAT3];
R168	NFE2L2 + PRKAA1	PRKAA1 \|NFE2L2	NFE2L2 + PRKAA1 → PRKAA1 \|NFE2L2	V(168) = K(168,1) * [PRKAA1] * [NFE2L2] -K(168,2) * [PRKAA1 \|NFE2L2];
R169	PRKAA1 \|NFE2L2	NFE2L2_p + PRKAA1	PRKAA1 \|NFE2L2 → NFE2L2_p + PRKAA1	V(169) = K(169,1) * [PRKAA1 \|NFE2L2];
R170	CDKN1B + HIPK2_p	HIPK2_p \|CDKN1B	CDKN1B + HIPK2_p → HIPK2_p \|CDKN1B	V(170) = K(170,1) * [HIPK2_p] * [CDKN1B] -K(170,2) * [HIPK2_p \|CDKN1B];
R171	HIPK2_p \|CDKN1B	CDKN1B_p + HIPK2_p	HIPK2_p \|CDKN1B → CDKN1B_p + HIPK2_p	V(171) = K(171,1) * [HIPK2_p \|CDKN1B];
R172	PRKAA1 + PRKAA1	PRKAA1 \|PRKAA1	PRKAA1 + PRKAA1 → PRKAA1 \|PRKAA1	V(172) = K(172,1) * [PRKAA1] * [PRKAA1] -K(172,2) * [PRKAA1 \|PRKAA1];
R173	PRKAA1 \|PRKAA1	PRKAA1 + PRKAA1_p	PRKAA1 \|PRKAA1 → PRKAA1 + PRKAA1_p	V(173) = K(173,1) * [PRKAA1 \|PRKAA1];
R174	LEPR + STAT3	LEPR \|STAT3	LEPR + STAT3 → LEPR \|STAT3	V(174) = K(174,1) * [LEPR] * [STAT3] -K(174,2) * [LEPR \|STAT3];
R175	LEPR \|STAT3	LEPR + STAT3_p	LEPR \|STAT3 → LEPR + STAT3_p	V(175) = K(175,1) * [LEPR \|STAT3];
R176	LYN_p + SOCS1	LYN_p \|SOCS1	LYN_p + SOCS1 → LYN_p \|SOCS1	V(176) = K(176,1) * [LYN_p] * [SOCS1] -K(176,2) * [LYN_p \|SOCS1];
R177	LYN_p \|SOCS1	LYN_p + SOCS1_p	LYN_p \|SOCS1 → LYN_p + SOCS1_p	V(177) = K(177,1) * [LYN_p \|SOCS1];
R178	STAT1 + TEK_p	TEK_p \|STAT1	STAT1 + TEK_p → TEK_p \|STAT1	V(178) = K(178,1) * [TEK_p] * [STAT1] -K(178,2) * [TEK_p \|STAT1];
R179	TEK_p \|STAT1	STAT1_p + TEK_p	TEK_p \|STAT1 → STAT1_p + TEK_p	V(179) = K(179,1) * [TEK_p \|STAT1];
R180	EGFR + LYN_p	LYN_p \|EGFR	EGFR + LYN_p → LYN_p \|EGFR	V(180) = K(180,1) * [LYN_p] * [EGFR] -K(180,2) * [LYN_p \|EGFR];
R181	LYN_p \|EGFR	EGFR_p + LYN_p	LYN_p \|EGFR → EGFR_p + LYN_p	V(181) = K(181,1) * [LYN_p \|EGFR];
R182	CTNNB1 + EGFR_p	EGFR_p \|CTNNB1	CTNNB1 + EGFR_p → EGFR_p \|CTNNB1	V(182) = K(182,1) * [EGFR_p] * [CTNNB1] -K(182,2) * [EGFR_p \|CTNNB1];
R183	EGFR_p \|CTNNB1	CTNNB1_p + EGFR_p	EGFR_p \|CTNNB1 → CTNNB1_p + EGFR_p	V(183) = K(183,1) * [EGFR_p \|CTNNB1];
R184	EGFR_p + PTPN11	EGFR_p \|PTPN11	EGFR_p + PTPN11 → EGFR_p \|PTPN11	V(184) = K(184,1) * [EGFR_p] * [PTPN11] -K(184,2) * [EGFR_p \|PTPN11];
R185	EGFR_p \|PTPN11	EGFR_p + PTPN11_p	EGFR_p \|PTPN11 → EGFR_p + PTPN11_p	V(185) = K(185,1) * [EGFR_p \|PTPN11];
R186	HIPK2_p + MDM2	HIPK2_p \|MDM2	HIPK2_p + MDM2 → HIPK2_p \|MDM2	V(186) = K(186,1) * [HIPK2_p] * [MDM2] -K(186,2) * [HIPK2_p \|MDM2];
R187	HIPK2_p \|MDM2	HIPK2_p + MDM2_p	HIPK2_p \|MDM2 → HIPK2_p + MDM2_p	V(187) = K(187,1) * [HIPK2_p \|MDM2];
R188	EP300 + ROCK2	ROCK2 \|EP300	EP300 + ROCK2 → ROCK2 \|EP300	V(188) = K(188,1) * [ROCK2] * [EP300] -K(188,2) * [ROCK2 \|EP300];
R189	ROCK2 \|EP300	EP300_p + ROCK2	ROCK2 \|EP300 → EP300_p + ROCK2	V(189) = K(189,1) * [ROCK2 \|EP300];
R190	MAPK1_p + STAT3	MAPK1_p \|STAT3	MAPK1_p + STAT3 → MAPK1_p \|STAT3	V(190) = K(190,1) * [MAPK1_p] * [STAT3] -K(190,2) * [MAPK1_p \|STAT3];
R191	MAPK1_p \|STAT3	MAPK1_p + STAT3_p	MAPK1_p \|STAT3 → MAPK1_p + STAT3_p	V(191) = K(191,1) * [MAPK1_p \|STAT3];
R192	MAPK6 + MAPK6_p	MAPK6_p \|MAPK6	MAPK6 + MAPK6_p → MAPK6_p \|MAPK6	V(192) = K(192,1) * [MAPK6_p] * [MAPK6] -K(192,2) * [MAPK6_p \|MAPK6];
R193	MAPK6_p \|MAPK6	MAPK6_p + MAPK6_p	MAPK6_p \|MAPK6 → MAPK6_p + MAPK6_p	V(193) = K(193,1) * [MAPK6_p \|MAPK6];
R194	MAPK1_p + NR4A1	MAPK1_p \|NR4A1	MAPK1_p + NR4A1 → MAPK1_p \|NR4A1	V(194) = K(194,1) * [MAPK1_p] * [NR4A1] -K(194,2) * [MAPK1_p \|NR4A1];
R195	MAPK1_p \|NR4A1	MAPK1_p + NR4A1_p	MAPK1_p \|NR4A1 → MAPK1_p + NR4A1_p	V(195) = K(195,1) * [MAPK1_p \|NR4A1];
R196	ABCA1 + EGFR_p	EGFR_p \|ABCA1	ABCA1 + EGFR_p → EGFR_p \|ABCA1	V(196) = K(196,1) * [EGFR_p] * [ABCA1] -K(196,2) * [EGFR_p \|ABCA1];
R197	EGFR_p \|ABCA1	ABCA1_p + EGFR_p	EGFR_p \|ABCA1 → ABCA1_p + EGFR_p	V(197) = K(197,1) * [EGFR_p \|ABCA1];
R198	MAPK9_p + STAT3	MAPK9_p \|STAT3	MAPK9_p + STAT3 → MAPK9_p \|STAT3	V(198) = K(198,1) * [MAPK9_p] * [STAT3] -K(198,2) * [MAPK9_p \|STAT3];
R199	MAPK9_p \|STAT3	MAPK9_p + STAT3_p	MAPK9_p \|STAT3 → MAPK9_p + STAT3_p	V(199) = K(199,1) * [MAPK9_p \|STAT3];