Monocyte Derived Cell_Parametric ODE Equations

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Reaction ID	Reactants	Products	Original Text	ODE Equations
R1	SP1_p + STAT3_p	SIGNOR-C74	SP1_p + STAT3_p → SIGNOR-C74	V(1) = K(1,1) * [STAT3_p] * [SP1_p] -K(1,2) * [SIGNOR-C74];
R2	STAT1_p + STAT3_p	SIGNOR-C118	STAT1_p + STAT3_p → SIGNOR-C118	V(2) = K(2,1) * [STAT1_p] * [STAT3_p] -K(2,2) * [SIGNOR-C118];
R3	JAK1_p + SIGNOR-C118_p	SIGNOR-C120	JAK1_p + SIGNOR-C118_p → SIGNOR-C120	V(3) = K(3,1) * [SIGNOR-C118_p] * [JAK1_p] -K(3,2) * [SIGNOR-C120];
R4	FOS_p + FOS_p + FOS_p + FOS_p + JUN_p + JUN_p + JUN_p + JUN_p	SIGNOR-C154	FOS_p + FOS_p + FOS_p + FOS_p + JUN_p + JUN_p + JUN_p + JUN_p → SIGNOR-C154	V(4) = K(4,1) * [FOS_p] * [JUN_p] * [JUN_p] * [FOS_p] * [JUN_p] * [FOS_p] * [FOS_p] * [JUN_p] -K(4,2) * [SIGNOR-C154];
R5	PIK3CA + PIK3R1_p	SIGNOR-C156	PIK3CA + PIK3R1_p → SIGNOR-C156	V(5) = K(5,1) * [PIK3R1_p] * [PIK3CA] -K(5,2) * [SIGNOR-C156];
R6	SMAD2 + TGFBR1	TGFBR1 \|SMAD2	SMAD2 + TGFBR1 → TGFBR1 \|SMAD2	V(6) = K(6,1) * [TGFBR1] * [SMAD2] -K(6,2) * [TGFBR1 \|SMAD2];
R7	TGFBR1 \|SMAD2	SMAD2_p + TGFBR1	TGFBR1 \|SMAD2 → SMAD2_p + TGFBR1	V(7) = K(7,1) * [TGFBR1 \|SMAD2];
R8	EP300 + MAPK1_p	MAPK1_p \|EP300	EP300 + MAPK1_p → MAPK1_p \|EP300	V(8) = K(8,1) * [MAPK1_p] * [EP300] -K(8,2) * [MAPK1_p \|EP300];
R9	MAPK1_p \|EP300	EP300_p + MAPK1_p	MAPK1_p \|EP300 → EP300_p + MAPK1_p	V(9) = K(9,1) * [MAPK1_p \|EP300];
R10	HIF1A + MAPK1_p	MAPK1_p \|HIF1A	HIF1A + MAPK1_p → MAPK1_p \|HIF1A	V(10) = K(10,1) * [MAPK1_p] * [HIF1A] -K(10,2) * [MAPK1_p \|HIF1A];
R11	MAPK1_p \|HIF1A	HIF1A_p + MAPK1_p	MAPK1_p \|HIF1A → HIF1A_p + MAPK1_p	V(11) = K(11,1) * [MAPK1_p \|HIF1A];
R12	MAPK1_p + RPS6KA3	MAPK1_p \|RPS6KA3	MAPK1_p + RPS6KA3 → MAPK1_p \|RPS6KA3	V(12) = K(12,1) * [MAPK1_p] * [RPS6KA3] -K(12,2) * [MAPK1_p \|RPS6KA3];
R13	MAPK1_p \|RPS6KA3	MAPK1_p + RPS6KA3_p	MAPK1_p \|RPS6KA3 → MAPK1_p + RPS6KA3_p	V(13) = K(13,1) * [MAPK1_p \|RPS6KA3];
R14	MAPK1_p + PRDX6	MAPK1_p \|PRDX6	MAPK1_p + PRDX6 → MAPK1_p \|PRDX6	V(14) = K(14,1) * [MAPK1_p] * [PRDX6] -K(14,2) * [MAPK1_p \|PRDX6];
R15	MAPK1_p \|PRDX6	MAPK1_p + PRDX6_p	MAPK1_p \|PRDX6 → MAPK1_p + PRDX6_p	V(15) = K(15,1) * [MAPK1_p \|PRDX6];
R16	FYN_p + STK11	FYN_p \|STK11	FYN_p + STK11 → FYN_p \|STK11	V(16) = K(16,1) * [FYN_p] * [STK11] -K(16,2) * [FYN_p \|STK11];
R17	FYN_p \|STK11	FYN_p + STK11_p	FYN_p \|STK11 → FYN_p + STK11_p	V(17) = K(17,1) * [FYN_p \|STK11];
R18	JAK2_p + STAT5A	JAK2_p \|STAT5A	JAK2_p + STAT5A → JAK2_p \|STAT5A	V(18) = K(18,1) * [JAK2_p] * [STAT5A] -K(18,2) * [JAK2_p \|STAT5A];
R19	JAK2_p \|STAT5A	JAK2_p + STAT5A_p	JAK2_p \|STAT5A → JAK2_p + STAT5A_p	V(19) = K(19,1) * [JAK2_p \|STAT5A];
R20	AKT1_p + MDM2	AKT1_p \|MDM2	AKT1_p + MDM2 → AKT1_p \|MDM2	V(20) = K(20,1) * [AKT1_p] * [MDM2] -K(20,2) * [AKT1_p \|MDM2];
R21	AKT1_p \|MDM2	AKT1_p + MDM2_p	AKT1_p \|MDM2 → AKT1_p + MDM2_p	V(21) = K(21,1) * [AKT1_p \|MDM2];
R22	CTLA4 + JAK2_p	JAK2_p \|CTLA4	CTLA4 + JAK2_p → JAK2_p \|CTLA4	V(22) = K(22,1) * [JAK2_p] * [CTLA4] -K(22,2) * [JAK2_p \|CTLA4];
R23	JAK2_p \|CTLA4	CTLA4_p + JAK2_p	JAK2_p \|CTLA4 → CTLA4_p + JAK2_p	V(23) = K(23,1) * [JAK2_p \|CTLA4];
R24	IKBKB + IKBKB_p	IKBKB_p \|IKBKB	IKBKB + IKBKB_p → IKBKB_p \|IKBKB	V(24) = K(24,1) * [IKBKB_p] * [IKBKB] -K(24,2) * [IKBKB_p \|IKBKB];
R25	IKBKB_p \|IKBKB	IKBKB_p + IKBKB_p	IKBKB_p \|IKBKB → IKBKB_p + IKBKB_p	V(25) = K(25,1) * [IKBKB_p \|IKBKB];
R26	JAK2 + JAK2_p	JAK2_p \|JAK2	JAK2 + JAK2_p → JAK2_p \|JAK2	V(26) = K(26,1) * [JAK2_p] * [JAK2] -K(26,2) * [JAK2_p \|JAK2];
R27	JAK2_p \|JAK2	JAK2_p + JAK2_p	JAK2_p \|JAK2 → JAK2_p + JAK2_p	V(27) = K(27,1) * [JAK2_p \|JAK2];
R28	DNM1L + ROCK1	ROCK1 \|DNM1L	DNM1L + ROCK1 → ROCK1 \|DNM1L	V(28) = K(28,1) * [ROCK1] * [DNM1L] -K(28,2) * [ROCK1 \|DNM1L];
R29	ROCK1 \|DNM1L	DNM1L_p + ROCK1	ROCK1 \|DNM1L → DNM1L_p + ROCK1	V(29) = K(29,1) * [ROCK1 \|DNM1L];
R30	MAPK1_p + STK11	MAPK1_p \|STK11	MAPK1_p + STK11 → MAPK1_p \|STK11	V(30) = K(30,1) * [MAPK1_p] * [STK11] -K(30,2) * [MAPK1_p \|STK11];
R31	MAPK1_p \|STK11	MAPK1_p + STK11_p	MAPK1_p \|STK11 → MAPK1_p + STK11_p	V(31) = K(31,1) * [MAPK1_p \|STK11];
R32	JUN + MAPK1_p	MAPK1_p \|JUN	JUN + MAPK1_p → MAPK1_p \|JUN	V(32) = K(32,1) * [MAPK1_p] * [JUN] -K(32,2) * [MAPK1_p \|JUN];
R33	MAPK1_p \|JUN	JUN_p + MAPK1_p	MAPK1_p \|JUN → JUN_p + MAPK1_p	V(33) = K(33,1) * [MAPK1_p \|JUN];
R34	BTK + SIGNOR-C156_p	SIGNOR-C156_p \|BTK	BTK + SIGNOR-C156_p → SIGNOR-C156_p \|BTK	V(34) = K(34,1) * [SIGNOR-C156_p] * [BTK] -K(34,2) * [SIGNOR-C156_p \|BTK];
R35	SIGNOR-C156_p \|BTK	BTK_p + SIGNOR-C156_p	SIGNOR-C156_p \|BTK → BTK_p + SIGNOR-C156_p	V(35) = K(35,1) * [SIGNOR-C156_p \|BTK];
R36	IKBKB + PDPK1_p	PDPK1_p \|IKBKB	IKBKB + PDPK1_p → PDPK1_p \|IKBKB	V(36) = K(36,1) * [PDPK1_p] * [IKBKB] -K(36,2) * [PDPK1_p \|IKBKB];
R37	PDPK1_p \|IKBKB	IKBKB_p + PDPK1_p	PDPK1_p \|IKBKB → IKBKB_p + PDPK1_p	V(37) = K(37,1) * [PDPK1_p \|IKBKB];
R38	CTLA4 + FYN_p	FYN_p \|CTLA4	CTLA4 + FYN_p → FYN_p \|CTLA4	V(38) = K(38,1) * [FYN_p] * [CTLA4] -K(38,2) * [FYN_p \|CTLA4];
R39	FYN_p \|CTLA4	CTLA4_p + FYN_p	FYN_p \|CTLA4 → CTLA4_p + FYN_p	V(39) = K(39,1) * [FYN_p \|CTLA4];
R40	AKT1_p + NR4A1	AKT1_p \|NR4A1	AKT1_p + NR4A1 → AKT1_p \|NR4A1	V(40) = K(40,1) * [AKT1_p] * [NR4A1] -K(40,2) * [AKT1_p \|NR4A1];
R41	AKT1_p \|NR4A1	AKT1_p + NR4A1_p	AKT1_p \|NR4A1 → AKT1_p + NR4A1_p	V(41) = K(41,1) * [AKT1_p \|NR4A1];
R42	JAK2_p + MAP3K5	JAK2_p \|MAP3K5	JAK2_p + MAP3K5 → JAK2_p \|MAP3K5	V(42) = K(42,1) * [JAK2_p] * [MAP3K5] -K(42,2) * [JAK2_p \|MAP3K5];
R43	JAK2_p \|MAP3K5	JAK2_p + MAP3K5_p	JAK2_p \|MAP3K5 → JAK2_p + MAP3K5_p	V(43) = K(43,1) * [JAK2_p \|MAP3K5];
R44	FOS + MAPK1_p	MAPK1_p \|FOS	FOS + MAPK1_p → MAPK1_p \|FOS	V(44) = K(44,1) * [MAPK1_p] * [FOS] -K(44,2) * [MAPK1_p \|FOS];
R45	MAPK1_p \|FOS	FOS_p + MAPK1_p	MAPK1_p \|FOS → FOS_p + MAPK1_p	V(45) = K(45,1) * [MAPK1_p \|FOS];
R46	STK11 + STK11_p	STK11_p \|STK11	STK11 + STK11_p → STK11_p \|STK11	V(46) = K(46,1) * [STK11_p] * [STK11] -K(46,2) * [STK11_p \|STK11];
R47	STK11_p \|STK11	STK11_p + STK11_p	STK11_p \|STK11 → STK11_p + STK11_p	V(47) = K(47,1) * [STK11_p \|STK11];
R48	CTNNB1 + JAK3_p	JAK3_p \|CTNNB1	CTNNB1 + JAK3_p → JAK3_p \|CTNNB1	V(48) = K(48,1) * [JAK3_p] * [CTNNB1] -K(48,2) * [JAK3_p \|CTNNB1];
R49	JAK3_p \|CTNNB1	CTNNB1_p + JAK3_p	JAK3_p \|CTNNB1 → CTNNB1_p + JAK3_p	V(49) = K(49,1) * [JAK3_p \|CTNNB1];
R50	FYN_p + PTPN6	FYN_p \|PTPN6	FYN_p + PTPN6 → FYN_p \|PTPN6	V(50) = K(50,1) * [FYN_p] * [PTPN6] -K(50,2) * [FYN_p \|PTPN6];
R51	FYN_p \|PTPN6	FYN_p + PTPN6_p	FYN_p \|PTPN6 → FYN_p + PTPN6_p	V(51) = K(51,1) * [FYN_p \|PTPN6];
R52	MAPK9_p + TP53	MAPK9_p \|TP53	MAPK9_p + TP53 → MAPK9_p \|TP53	V(52) = K(52,1) * [MAPK9_p] * [TP53] -K(52,2) * [MAPK9_p \|TP53];
R53	MAPK9_p \|TP53	MAPK9_p + TP53_p	MAPK9_p \|TP53 → MAPK9_p + TP53_p	V(53) = K(53,1) * [MAPK9_p \|TP53];
R54	MAPK1_p + SMAD2	MAPK1_p \|SMAD2	MAPK1_p + SMAD2 → MAPK1_p \|SMAD2	V(54) = K(54,1) * [MAPK1_p] * [SMAD2] -K(54,2) * [MAPK1_p \|SMAD2];
R55	MAPK1_p \|SMAD2	MAPK1_p + SMAD2_p	MAPK1_p \|SMAD2 → MAPK1_p + SMAD2_p	V(55) = K(55,1) * [MAPK1_p \|SMAD2];
R56	CTNNB1 + KIT_p	KIT_p \|CTNNB1	CTNNB1 + KIT_p → KIT_p \|CTNNB1	V(56) = K(56,1) * [KIT_p] * [CTNNB1] -K(56,2) * [KIT_p \|CTNNB1];
R57	KIT_p \|CTNNB1	CTNNB1_p + KIT_p	KIT_p \|CTNNB1 → CTNNB1_p + KIT_p	V(57) = K(57,1) * [KIT_p \|CTNNB1];
R58	JUN + MAPK9_p	MAPK9_p \|JUN	JUN + MAPK9_p → MAPK9_p \|JUN	V(58) = K(58,1) * [MAPK9_p] * [JUN] -K(58,2) * [MAPK9_p \|JUN];
R59	MAPK9_p \|JUN	JUN_p + MAPK9_p	MAPK9_p \|JUN → JUN_p + MAPK9_p	V(59) = K(59,1) * [MAPK9_p \|JUN];
R60	BCL2 + MAPK1_p	MAPK1_p \|BCL2	BCL2 + MAPK1_p → MAPK1_p \|BCL2	V(60) = K(60,1) * [MAPK1_p] * [BCL2] -K(60,2) * [MAPK1_p \|BCL2];
R61	MAPK1_p \|BCL2	BCL2_p + MAPK1_p	MAPK1_p \|BCL2 → BCL2_p + MAPK1_p	V(61) = K(61,1) * [MAPK1_p \|BCL2];
R62	INSR + INSR_p	INSR_p \|INSR	INSR + INSR_p → INSR_p \|INSR	V(62) = K(62,1) * [INSR_p] * [INSR] -K(62,2) * [INSR_p \|INSR];
R63	INSR_p \|INSR	INSR_p + INSR_p	INSR_p \|INSR → INSR_p + INSR_p	V(63) = K(63,1) * [INSR_p \|INSR];
R64	AKT1_p + BAD	AKT1_p \|BAD	AKT1_p + BAD → AKT1_p \|BAD	V(64) = K(64,1) * [AKT1_p] * [BAD] -K(64,2) * [AKT1_p \|BAD];
R65	AKT1_p \|BAD	AKT1_p + BAD_p	AKT1_p \|BAD → AKT1_p + BAD_p	V(65) = K(65,1) * [AKT1_p \|BAD];
R66	MAPK1_p + NCF1	MAPK1_p \|NCF1	MAPK1_p + NCF1 → MAPK1_p \|NCF1	V(66) = K(66,1) * [MAPK1_p] * [NCF1] -K(66,2) * [MAPK1_p \|NCF1];
R67	MAPK1_p \|NCF1	MAPK1_p + NCF1_p	MAPK1_p \|NCF1 → MAPK1_p + NCF1_p	V(67) = K(67,1) * [MAPK1_p \|NCF1];
R68	JAK1_p + STAT1	JAK1_p \|STAT1	JAK1_p + STAT1 → JAK1_p \|STAT1	V(68) = K(68,1) * [JAK1_p] * [STAT1] -K(68,2) * [JAK1_p \|STAT1];
R69	JAK1_p \|STAT1	JAK1_p + STAT1_p	JAK1_p \|STAT1 → JAK1_p + STAT1_p	V(69) = K(69,1) * [JAK1_p \|STAT1];
R70	DUSP1 + MAPK1_p	MAPK1_p \|DUSP1	DUSP1 + MAPK1_p → MAPK1_p \|DUSP1	V(70) = K(70,1) * [MAPK1_p] * [DUSP1] -K(70,2) * [MAPK1_p \|DUSP1];
R71	MAPK1_p \|DUSP1	DUSP1_p + MAPK1_p	MAPK1_p \|DUSP1 → DUSP1_p + MAPK1_p	V(71) = K(71,1) * [MAPK1_p \|DUSP1];
R72	AKT1_p + NCF1	AKT1_p \|NCF1	AKT1_p + NCF1 → AKT1_p \|NCF1	V(72) = K(72,1) * [AKT1_p] * [NCF1] -K(72,2) * [AKT1_p \|NCF1];
R73	AKT1_p \|NCF1	AKT1_p + NCF1_p	AKT1_p \|NCF1 → AKT1_p + NCF1_p	V(73) = K(73,1) * [AKT1_p \|NCF1];
R74	PKN1 + PKN1_p	PKN1_p \|PKN1	PKN1 + PKN1_p → PKN1_p \|PKN1	V(74) = K(74,1) * [PKN1_p] * [PKN1] -K(74,2) * [PKN1_p \|PKN1];
R75	PKN1_p \|PKN1	PKN1_p + PKN1_p	PKN1_p \|PKN1 → PKN1_p + PKN1_p	V(75) = K(75,1) * [PKN1_p \|PKN1];
R76	AKT1_p + CDKN1A	AKT1_p \|CDKN1A	AKT1_p + CDKN1A → AKT1_p \|CDKN1A	V(76) = K(76,1) * [AKT1_p] * [CDKN1A] -K(76,2) * [AKT1_p \|CDKN1A];
R77	AKT1_p \|CDKN1A	AKT1_p + CDKN1A_p	AKT1_p \|CDKN1A → AKT1_p + CDKN1A_p	V(77) = K(77,1) * [AKT1_p \|CDKN1A];
R78	JAK3_p + STAT5A	JAK3_p \|STAT5A	JAK3_p + STAT5A → JAK3_p \|STAT5A	V(78) = K(78,1) * [JAK3_p] * [STAT5A] -K(78,2) * [JAK3_p \|STAT5A];
R79	JAK3_p \|STAT5A	JAK3_p + STAT5A_p	JAK3_p \|STAT5A → JAK3_p + STAT5A_p	V(79) = K(79,1) * [JAK3_p \|STAT5A];
R80	JAK1 + JAK3_p	JAK3_p \|JAK1	JAK1 + JAK3_p → JAK3_p \|JAK1	V(80) = K(80,1) * [JAK3_p] * [JAK1] -K(80,2) * [JAK3_p \|JAK1];
R81	JAK3_p \|JAK1	JAK1_p + JAK3_p	JAK3_p \|JAK1 → JAK1_p + JAK3_p	V(81) = K(81,1) * [JAK3_p \|JAK1];
R82	KIT + KIT_p	KIT_p \|KIT	KIT + KIT_p → KIT_p \|KIT	V(82) = K(82,1) * [KIT_p] * [KIT] -K(82,2) * [KIT_p \|KIT];
R83	KIT_p \|KIT	KIT_p + KIT_p	KIT_p \|KIT → KIT_p + KIT_p	V(83) = K(83,1) * [KIT_p \|KIT];
R84	INSR_p + SIGNOR-C156	INSR_p \|SIGNOR-C156	INSR_p + SIGNOR-C156 → INSR_p \|SIGNOR-C156	V(84) = K(84,1) * [INSR_p] * [SIGNOR-C156] -K(84,2) * [INSR_p \|SIGNOR-C156];
R85	INSR_p \|SIGNOR-C156	INSR_p + SIGNOR-C156_p	INSR_p \|SIGNOR-C156 → INSR_p + SIGNOR-C156_p	V(85) = K(85,1) * [INSR_p \|SIGNOR-C156];
R86	MAPK1_p + RHOA	MAPK1_p \|RHOA	MAPK1_p + RHOA → MAPK1_p \|RHOA	V(86) = K(86,1) * [MAPK1_p] * [RHOA] -K(86,2) * [MAPK1_p \|RHOA];
R87	MAPK1_p \|RHOA	MAPK1_p + RHOA_p	MAPK1_p \|RHOA → MAPK1_p + RHOA_p	V(87) = K(87,1) * [MAPK1_p \|RHOA];
R88	EPOR + JAK2_p	JAK2_p \|EPOR	EPOR + JAK2_p → JAK2_p \|EPOR	V(88) = K(88,1) * [JAK2_p] * [EPOR] -K(88,2) * [JAK2_p \|EPOR];
R89	JAK2_p \|EPOR	EPOR_p + JAK2_p	JAK2_p \|EPOR → EPOR_p + JAK2_p	V(89) = K(89,1) * [JAK2_p \|EPOR];
R90	AKT1_p + PPARGC1A	AKT1_p \|PPARGC1A	AKT1_p + PPARGC1A → AKT1_p \|PPARGC1A	V(90) = K(90,1) * [AKT1_p] * [PPARGC1A] -K(90,2) * [AKT1_p \|PPARGC1A];
R91	AKT1_p \|PPARGC1A	AKT1_p + PPARGC1A_p	AKT1_p \|PPARGC1A → AKT1_p + PPARGC1A_p	V(91) = K(91,1) * [AKT1_p \|PPARGC1A];
R92	ATR + PARP1	ATR \|PARP1	ATR + PARP1 → ATR \|PARP1	V(92) = K(92,1) * [ATR] * [PARP1] -K(92,2) * [ATR \|PARP1];
R93	ATR \|PARP1	ATR + PARP1_p	ATR \|PARP1 → ATR + PARP1_p	V(93) = K(93,1) * [ATR \|PARP1];
R94	JAK2_p + STAT1	JAK2_p \|STAT1	JAK2_p + STAT1 → JAK2_p \|STAT1	V(94) = K(94,1) * [JAK2_p] * [STAT1] -K(94,2) * [JAK2_p \|STAT1];
R95	JAK2_p \|STAT1	JAK2_p + STAT1_p	JAK2_p \|STAT1 → JAK2_p + STAT1_p	V(95) = K(95,1) * [JAK2_p \|STAT1];
R96	MAPK1_p + TFEB	MAPK1_p \|TFEB	MAPK1_p + TFEB → MAPK1_p \|TFEB	V(96) = K(96,1) * [MAPK1_p] * [TFEB] -K(96,2) * [MAPK1_p \|TFEB];
R97	MAPK1_p \|TFEB	MAPK1_p + TFEB_p	MAPK1_p \|TFEB → MAPK1_p + TFEB_p	V(97) = K(97,1) * [MAPK1_p \|TFEB];
R98	PDPK1_p + SGK1	PDPK1_p \|SGK1	PDPK1_p + SGK1 → PDPK1_p \|SGK1	V(98) = K(98,1) * [PDPK1_p] * [SGK1] -K(98,2) * [PDPK1_p \|SGK1];
R99	PDPK1_p \|SGK1	PDPK1_p + SGK1_p	PDPK1_p \|SGK1 → PDPK1_p + SGK1_p	V(99) = K(99,1) * [PDPK1_p \|SGK1];
R100	ERN1 + ERN1_p	ERN1_p \|ERN1	ERN1 + ERN1_p → ERN1_p \|ERN1	V(100) = K(100,1) * [ERN1_p] * [ERN1] -K(100,2) * [ERN1_p \|ERN1];
R101	ERN1_p \|ERN1	ERN1_p + ERN1_p	ERN1_p \|ERN1 → ERN1_p + ERN1_p	V(101) = K(101,1) * [ERN1_p \|ERN1];
R102	DEPTOR + RPS6KA3_p	RPS6KA3_p \|DEPTOR	DEPTOR + RPS6KA3_p → RPS6KA3_p \|DEPTOR	V(102) = K(102,1) * [RPS6KA3_p] * [DEPTOR] -K(102,2) * [RPS6KA3_p \|DEPTOR];
R103	RPS6KA3_p \|DEPTOR	DEPTOR_p + RPS6KA3_p	RPS6KA3_p \|DEPTOR → DEPTOR_p + RPS6KA3_p	V(103) = K(103,1) * [RPS6KA3_p \|DEPTOR];
R104	MAP3K5 + RPS6KA3_p	RPS6KA3_p \|MAP3K5	MAP3K5 + RPS6KA3_p → RPS6KA3_p \|MAP3K5	V(104) = K(104,1) * [RPS6KA3_p] * [MAP3K5] -K(104,2) * [RPS6KA3_p \|MAP3K5];
R105	RPS6KA3_p \|MAP3K5	MAP3K5_p + RPS6KA3_p	RPS6KA3_p \|MAP3K5 → MAP3K5_p + RPS6KA3_p	V(105) = K(105,1) * [RPS6KA3_p \|MAP3K5];
R106	ATR + MDM2	ATR \|MDM2	ATR + MDM2 → ATR \|MDM2	V(106) = K(106,1) * [ATR] * [MDM2] -K(106,2) * [ATR \|MDM2];
R107	ATR \|MDM2	ATR + MDM2_p	ATR \|MDM2 → ATR + MDM2_p	V(107) = K(107,1) * [ATR \|MDM2];
R108	MAPK1_p + SIGNOR-C154	MAPK1_p \|SIGNOR-C154	MAPK1_p + SIGNOR-C154 → MAPK1_p \|SIGNOR-C154	V(108) = K(108,1) * [MAPK1_p] * [SIGNOR-C154] -K(108,2) * [MAPK1_p \|SIGNOR-C154];
R109	MAPK1_p \|SIGNOR-C154	MAPK1_p + SIGNOR-C154_p	MAPK1_p \|SIGNOR-C154 → MAPK1_p + SIGNOR-C154_p	V(109) = K(109,1) * [MAPK1_p \|SIGNOR-C154];
R110	BAD + RPS6KA3_p	RPS6KA3_p \|BAD	BAD + RPS6KA3_p → RPS6KA3_p \|BAD	V(110) = K(110,1) * [RPS6KA3_p] * [BAD] -K(110,2) * [RPS6KA3_p \|BAD];
R111	RPS6KA3_p \|BAD	BAD_p + RPS6KA3_p	RPS6KA3_p \|BAD → BAD_p + RPS6KA3_p	V(111) = K(111,1) * [RPS6KA3_p \|BAD];
R112	CTNNB1 + MAPK9_p	MAPK9_p \|CTNNB1	CTNNB1 + MAPK9_p → MAPK9_p \|CTNNB1	V(112) = K(112,1) * [MAPK9_p] * [CTNNB1] -K(112,2) * [MAPK9_p \|CTNNB1];
R113	MAPK9_p \|CTNNB1	CTNNB1_p + MAPK9_p	MAPK9_p \|CTNNB1 → CTNNB1_p + MAPK9_p	V(113) = K(113,1) * [MAPK9_p \|CTNNB1];
R114	PINK1 + UBC	PINK1 \|UBC	PINK1 + UBC → PINK1 \|UBC	V(114) = K(114,1) * [PINK1] * [UBC] -K(114,2) * [PINK1 \|UBC];
R115	PINK1 \|UBC	PINK1 + UBC_p	PINK1 \|UBC → PINK1 + UBC_p	V(115) = K(115,1) * [PINK1 \|UBC];
R116	AKT1_p + RAC1	AKT1_p \|RAC1	AKT1_p + RAC1 → AKT1_p \|RAC1	V(116) = K(116,1) * [AKT1_p] * [RAC1] -K(116,2) * [AKT1_p \|RAC1];
R117	AKT1_p \|RAC1	AKT1_p + RAC1_p	AKT1_p \|RAC1 → AKT1_p + RAC1_p	V(117) = K(117,1) * [AKT1_p \|RAC1];
R118	AKT1 + PDPK1_p	PDPK1_p \|AKT1	AKT1 + PDPK1_p → PDPK1_p \|AKT1	V(118) = K(118,1) * [PDPK1_p] * [AKT1] -K(118,2) * [PDPK1_p \|AKT1];
R119	PDPK1_p \|AKT1	AKT1_p + PDPK1_p	PDPK1_p \|AKT1 → AKT1_p + PDPK1_p	V(119) = K(119,1) * [PDPK1_p \|AKT1];
R120	STK4 + STK4_p	STK4_p \|STK4	STK4 + STK4_p → STK4_p \|STK4	V(120) = K(120,1) * [STK4_p] * [STK4] -K(120,2) * [STK4_p \|STK4];
R121	STK4_p \|STK4	STK4_p + STK4_p	STK4_p \|STK4 → STK4_p + STK4_p	V(121) = K(121,1) * [STK4_p \|STK4];
R122	PTEN + STK11_p	STK11_p \|PTEN	PTEN + STK11_p → STK11_p \|PTEN	V(122) = K(122,1) * [STK11_p] * [PTEN] -K(122,2) * [STK11_p \|PTEN];
R123	STK11_p \|PTEN	PTEN_p + STK11_p	STK11_p \|PTEN → PTEN_p + STK11_p	V(123) = K(123,1) * [STK11_p \|PTEN];
R124	HIPK2 + HIPK2_p	HIPK2_p \|HIPK2	HIPK2 + HIPK2_p → HIPK2_p \|HIPK2	V(124) = K(124,1) * [HIPK2_p] * [HIPK2] -K(124,2) * [HIPK2_p \|HIPK2];
R125	HIPK2_p \|HIPK2	HIPK2_p + HIPK2_p	HIPK2_p \|HIPK2 → HIPK2_p + HIPK2_p	V(125) = K(125,1) * [HIPK2_p \|HIPK2];
R126	BECN1 + JAK2_p	JAK2_p \|BECN1	BECN1 + JAK2_p → JAK2_p \|BECN1	V(126) = K(126,1) * [JAK2_p] * [BECN1] -K(126,2) * [JAK2_p \|BECN1];
R127	JAK2_p \|BECN1	BECN1_p + JAK2_p	JAK2_p \|BECN1 → BECN1_p + JAK2_p	V(127) = K(127,1) * [JAK2_p \|BECN1];
R128	PDPK1 + PDPK1_p	PDPK1_p \|PDPK1	PDPK1 + PDPK1_p → PDPK1_p \|PDPK1	V(128) = K(128,1) * [PDPK1_p] * [PDPK1] -K(128,2) * [PDPK1_p \|PDPK1];
R129	PDPK1_p \|PDPK1	PDPK1_p + PDPK1_p	PDPK1_p \|PDPK1 → PDPK1_p + PDPK1_p	V(129) = K(129,1) * [PDPK1_p \|PDPK1];
R130	AKT1_p + EP300	AKT1_p \|EP300	AKT1_p + EP300 → AKT1_p \|EP300	V(130) = K(130,1) * [AKT1_p] * [EP300] -K(130,2) * [AKT1_p \|EP300];
R131	AKT1_p \|EP300	AKT1_p + EP300_p	AKT1_p \|EP300 → AKT1_p + EP300_p	V(131) = K(131,1) * [AKT1_p \|EP300];
R132	FYN + FYN_p	FYN_p \|FYN	FYN + FYN_p → FYN_p \|FYN	V(132) = K(132,1) * [FYN_p] * [FYN] -K(132,2) * [FYN_p \|FYN];
R133	FYN_p \|FYN	FYN_p + FYN_p	FYN_p \|FYN → FYN_p + FYN_p	V(133) = K(133,1) * [FYN_p \|FYN];
R134	IRAK1 + IRAK1_p	IRAK1_p \|IRAK1	IRAK1 + IRAK1_p → IRAK1_p \|IRAK1	V(134) = K(134,1) * [IRAK1_p] * [IRAK1] -K(134,2) * [IRAK1_p \|IRAK1];
R135	IRAK1_p \|IRAK1	IRAK1_p + IRAK1_p	IRAK1_p \|IRAK1 → IRAK1_p + IRAK1_p	V(135) = K(135,1) * [IRAK1_p \|IRAK1];
R136	BAD + SIGNOR-C156_p	SIGNOR-C156_p \|BAD	BAD + SIGNOR-C156_p → SIGNOR-C156_p \|BAD	V(136) = K(136,1) * [SIGNOR-C156_p] * [BAD] -K(136,2) * [SIGNOR-C156_p \|BAD];
R137	SIGNOR-C156_p \|BAD	BAD_p + SIGNOR-C156_p	SIGNOR-C156_p \|BAD → BAD_p + SIGNOR-C156_p	V(137) = K(137,1) * [SIGNOR-C156_p \|BAD];
R138	MAP3K5 + MAP3K5_p	MAP3K5_p \|MAP3K5	MAP3K5 + MAP3K5_p → MAP3K5_p \|MAP3K5	V(138) = K(138,1) * [MAP3K5_p] * [MAP3K5] -K(138,2) * [MAP3K5_p \|MAP3K5];
R139	MAP3K5_p \|MAP3K5	MAP3K5_p + MAP3K5_p	MAP3K5_p \|MAP3K5 → MAP3K5_p + MAP3K5_p	V(139) = K(139,1) * [MAP3K5_p \|MAP3K5];
R140	IKBKB_p + NFKB1	IKBKB_p \|NFKB1	IKBKB_p + NFKB1 → IKBKB_p \|NFKB1	V(140) = K(140,1) * [IKBKB_p] * [NFKB1] -K(140,2) * [IKBKB_p \|NFKB1];
R141	IKBKB_p \|NFKB1	IKBKB_p + NFKB1_p	IKBKB_p \|NFKB1 → IKBKB_p + NFKB1_p	V(141) = K(141,1) * [IKBKB_p \|NFKB1];
R142	AKT1 + ILK_p	ILK_p \|AKT1	AKT1 + ILK_p → ILK_p \|AKT1	V(142) = K(142,1) * [ILK_p] * [AKT1] -K(142,2) * [ILK_p \|AKT1];
R143	ILK_p \|AKT1	AKT1_p + ILK_p	ILK_p \|AKT1 → AKT1_p + ILK_p	V(143) = K(143,1) * [ILK_p \|AKT1];
R144	AKT1_p + BTK	AKT1_p \|BTK	AKT1_p + BTK → AKT1_p \|BTK	V(144) = K(144,1) * [AKT1_p] * [BTK] -K(144,2) * [AKT1_p \|BTK];
R145	AKT1_p \|BTK	AKT1_p + BTK_p	AKT1_p \|BTK → AKT1_p + BTK_p	V(145) = K(145,1) * [AKT1_p \|BTK];
R146	MAPK1_p + SP1	MAPK1_p \|SP1	MAPK1_p + SP1 → MAPK1_p \|SP1	V(146) = K(146,1) * [MAPK1_p] * [SP1] -K(146,2) * [MAPK1_p \|SP1];
R147	MAPK1_p \|SP1	MAPK1_p + SP1_p	MAPK1_p \|SP1 → MAPK1_p + SP1_p	V(147) = K(147,1) * [MAPK1_p \|SP1];
R148	PTEN + ROCK1	ROCK1 \|PTEN	PTEN + ROCK1 → ROCK1 \|PTEN	V(148) = K(148,1) * [ROCK1] * [PTEN] -K(148,2) * [ROCK1 \|PTEN];
R149	ROCK1 \|PTEN	PTEN_p + ROCK1	ROCK1 \|PTEN → PTEN_p + ROCK1	V(149) = K(149,1) * [ROCK1 \|PTEN];
R150	MAPK1_p + STAT5A	MAPK1_p \|STAT5A	MAPK1_p + STAT5A → MAPK1_p \|STAT5A	V(150) = K(150,1) * [MAPK1_p] * [STAT5A] -K(150,2) * [MAPK1_p \|STAT5A];
R151	MAPK1_p \|STAT5A	MAPK1_p + STAT5A_p	MAPK1_p \|STAT5A → MAPK1_p + STAT5A_p	V(151) = K(151,1) * [MAPK1_p \|STAT5A];
R152	BAD + MAPK1_p	MAPK1_p \|BAD	BAD + MAPK1_p → MAPK1_p \|BAD	V(152) = K(152,1) * [MAPK1_p] * [BAD] -K(152,2) * [MAPK1_p \|BAD];
R153	MAPK1_p \|BAD	BAD_p + MAPK1_p	MAPK1_p \|BAD → BAD_p + MAPK1_p	V(153) = K(153,1) * [MAPK1_p \|BAD];
R154	PDPK1_p + RPS6KA3	PDPK1_p \|RPS6KA3	PDPK1_p + RPS6KA3 → PDPK1_p \|RPS6KA3	V(154) = K(154,1) * [PDPK1_p] * [RPS6KA3] -K(154,2) * [PDPK1_p \|RPS6KA3];
R155	PDPK1_p \|RPS6KA3	PDPK1_p + RPS6KA3_p	PDPK1_p \|RPS6KA3 → PDPK1_p + RPS6KA3_p	V(155) = K(155,1) * [PDPK1_p \|RPS6KA3];
R156	CDKN1A + MAPK1_p	MAPK1_p \|CDKN1A	CDKN1A + MAPK1_p → MAPK1_p \|CDKN1A	V(156) = K(156,1) * [MAPK1_p] * [CDKN1A] -K(156,2) * [MAPK1_p \|CDKN1A];
R157	MAPK1_p \|CDKN1A	CDKN1A_p + MAPK1_p	MAPK1_p \|CDKN1A → CDKN1A_p + MAPK1_p	V(157) = K(157,1) * [MAPK1_p \|CDKN1A];
R158	AKT1S1 + AKT1_p	AKT1_p \|AKT1S1	AKT1S1 + AKT1_p → AKT1_p \|AKT1S1	V(158) = K(158,1) * [AKT1_p] * [AKT1S1] -K(158,2) * [AKT1_p \|AKT1S1];
R159	AKT1_p \|AKT1S1	AKT1S1_p + AKT1_p	AKT1_p \|AKT1S1 → AKT1S1_p + AKT1_p	V(159) = K(159,1) * [AKT1_p \|AKT1S1];
R160	JAK3 + JAK3_p	JAK3_p \|JAK3	JAK3 + JAK3_p → JAK3_p \|JAK3	V(160) = K(160,1) * [JAK3_p] * [JAK3] -K(160,2) * [JAK3_p \|JAK3];
R161	JAK3_p \|JAK3	JAK3_p + JAK3_p	JAK3_p \|JAK3 → JAK3_p + JAK3_p	V(161) = K(161,1) * [JAK3_p \|JAK3];
R162	IL6R + JAK2	IL6R \|JAK2	IL6R + JAK2 → IL6R \|JAK2	V(162) = K(162,1) * [IL6R] * [JAK2] -K(162,2) * [IL6R \|JAK2];
R163	IL6R \|JAK2	IL6R + JAK2_p	IL6R \|JAK2 → IL6R + JAK2_p	V(163) = K(163,1) * [IL6R \|JAK2];
R164	JAK2 + MAPK1_p	MAPK1_p \|JAK2	JAK2 + MAPK1_p → MAPK1_p \|JAK2	V(164) = K(164,1) * [MAPK1_p] * [JAK2] -K(164,2) * [MAPK1_p \|JAK2];
R165	MAPK1_p \|JAK2	JAK2_p + MAPK1_p	MAPK1_p \|JAK2 → JAK2_p + MAPK1_p	V(165) = K(165,1) * [MAPK1_p \|JAK2];
R166	JAK1_p + STAT3	JAK1_p \|STAT3	JAK1_p + STAT3 → JAK1_p \|STAT3	V(166) = K(166,1) * [JAK1_p] * [STAT3] -K(166,2) * [JAK1_p \|STAT3];
R167	JAK1_p \|STAT3	JAK1_p + STAT3_p	JAK1_p \|STAT3 → JAK1_p + STAT3_p	V(167) = K(167,1) * [JAK1_p \|STAT3];
R168	MAPK1_p + PARP1	MAPK1_p \|PARP1	MAPK1_p + PARP1 → MAPK1_p \|PARP1	V(168) = K(168,1) * [MAPK1_p] * [PARP1] -K(168,2) * [MAPK1_p \|PARP1];
R169	MAPK1_p \|PARP1	MAPK1_p + PARP1_p	MAPK1_p \|PARP1 → MAPK1_p + PARP1_p	V(169) = K(169,1) * [MAPK1_p \|PARP1];
R170	FYN_p + PTGS2	FYN_p \|PTGS2	FYN_p + PTGS2 → FYN_p \|PTGS2	V(170) = K(170,1) * [FYN_p] * [PTGS2] -K(170,2) * [FYN_p \|PTGS2];
R171	FYN_p \|PTGS2	FYN_p + PTGS2_p	FYN_p \|PTGS2 → FYN_p + PTGS2_p	V(171) = K(171,1) * [FYN_p \|PTGS2];
R172	PIK3CA + STK4_p	STK4_p \|PIK3CA	PIK3CA + STK4_p → STK4_p \|PIK3CA	V(172) = K(172,1) * [STK4_p] * [PIK3CA] -K(172,2) * [STK4_p \|PIK3CA];
R173	STK4_p \|PIK3CA	PIK3CA_p + STK4_p	STK4_p \|PIK3CA → PIK3CA_p + STK4_p	V(173) = K(173,1) * [STK4_p \|PIK3CA];
R174	AKT1 + SIGNOR-C156_p	SIGNOR-C156_p \|AKT1	AKT1 + SIGNOR-C156_p → SIGNOR-C156_p \|AKT1	V(174) = K(174,1) * [SIGNOR-C156_p] * [AKT1] -K(174,2) * [SIGNOR-C156_p \|AKT1];
R175	SIGNOR-C156_p \|AKT1	AKT1_p + SIGNOR-C156_p	SIGNOR-C156_p \|AKT1 → AKT1_p + SIGNOR-C156_p	V(175) = K(175,1) * [SIGNOR-C156_p \|AKT1];
R176	BTK_p + STAT3	BTK_p \|STAT3	BTK_p + STAT3 → BTK_p \|STAT3	V(176) = K(176,1) * [BTK_p] * [STAT3] -K(176,2) * [BTK_p \|STAT3];
R177	BTK_p \|STAT3	BTK_p + STAT3_p	BTK_p \|STAT3 → BTK_p + STAT3_p	V(177) = K(177,1) * [BTK_p \|STAT3];
R178	IRF3 + STK4_p	STK4_p \|IRF3	IRF3 + STK4_p → STK4_p \|IRF3	V(178) = K(178,1) * [STK4_p] * [IRF3] -K(178,2) * [STK4_p \|IRF3];
R179	STK4_p \|IRF3	IRF3_p + STK4_p	STK4_p \|IRF3 → IRF3_p + STK4_p	V(179) = K(179,1) * [STK4_p \|IRF3];
R180	FOS + RPS6KA3_p	RPS6KA3_p \|FOS	FOS + RPS6KA3_p → RPS6KA3_p \|FOS	V(180) = K(180,1) * [RPS6KA3_p] * [FOS] -K(180,2) * [RPS6KA3_p \|FOS];
R181	RPS6KA3_p \|FOS	FOS_p + RPS6KA3_p	RPS6KA3_p \|FOS → FOS_p + RPS6KA3_p	V(181) = K(181,1) * [RPS6KA3_p \|FOS];
R182	AKT1_p + RPS6KA3	AKT1_p \|RPS6KA3	AKT1_p + RPS6KA3 → AKT1_p \|RPS6KA3	V(182) = K(182,1) * [AKT1_p] * [RPS6KA3] -K(182,2) * [AKT1_p \|RPS6KA3];
R183	AKT1_p \|RPS6KA3	AKT1_p + RPS6KA3_p	AKT1_p \|RPS6KA3 → AKT1_p + RPS6KA3_p	V(183) = K(183,1) * [AKT1_p \|RPS6KA3];
R184	KIT_p + STAT1	KIT_p \|STAT1	KIT_p + STAT1 → KIT_p \|STAT1	V(184) = K(184,1) * [KIT_p] * [STAT1] -K(184,2) * [KIT_p \|STAT1];
R185	KIT_p \|STAT1	KIT_p + STAT1_p	KIT_p \|STAT1 → KIT_p + STAT1_p	V(185) = K(185,1) * [KIT_p \|STAT1];
R186	AKT1_p + DNMT1	AKT1_p \|DNMT1	AKT1_p + DNMT1 → AKT1_p \|DNMT1	V(186) = K(186,1) * [AKT1_p] * [DNMT1] -K(186,2) * [AKT1_p \|DNMT1];
R187	AKT1_p \|DNMT1	AKT1_p + DNMT1_p	AKT1_p \|DNMT1 → AKT1_p + DNMT1_p	V(187) = K(187,1) * [AKT1_p \|DNMT1];
R188	SIRT1 + STK11_p	STK11_p \|SIRT1	SIRT1 + STK11_p → STK11_p \|SIRT1	V(188) = K(188,1) * [STK11_p] * [SIRT1] -K(188,2) * [STK11_p \|SIRT1];
R189	STK11_p \|SIRT1	SIRT1_p + STK11_p	STK11_p \|SIRT1 → SIRT1_p + STK11_p	V(189) = K(189,1) * [STK11_p \|SIRT1];
R190	RPS6KA3 + RPS6KA3_p	RPS6KA3_p \|RPS6KA3	RPS6KA3 + RPS6KA3_p → RPS6KA3_p \|RPS6KA3	V(190) = K(190,1) * [RPS6KA3_p] * [RPS6KA3] -K(190,2) * [RPS6KA3_p \|RPS6KA3];
R191	RPS6KA3_p \|RPS6KA3	RPS6KA3_p + RPS6KA3_p	RPS6KA3_p \|RPS6KA3 → RPS6KA3_p + RPS6KA3_p	V(191) = K(191,1) * [RPS6KA3_p \|RPS6KA3];
R192	AKT1_p + CTNNB1	AKT1_p \|CTNNB1	AKT1_p + CTNNB1 → AKT1_p \|CTNNB1	V(192) = K(192,1) * [AKT1_p] * [CTNNB1] -K(192,2) * [AKT1_p \|CTNNB1];
R193	AKT1_p \|CTNNB1	AKT1_p + CTNNB1_p	AKT1_p \|CTNNB1 → AKT1_p + CTNNB1_p	V(193) = K(193,1) * [AKT1_p \|CTNNB1];
R194	AKT1_p + STK4	AKT1_p \|STK4	AKT1_p + STK4 → AKT1_p \|STK4	V(194) = K(194,1) * [AKT1_p] * [STK4] -K(194,2) * [AKT1_p \|STK4];
R195	AKT1_p \|STK4	AKT1_p + STK4_p	AKT1_p \|STK4 → AKT1_p + STK4_p	V(195) = K(195,1) * [AKT1_p \|STK4];
R196	NR4A1 + RPS6KA3_p	RPS6KA3_p \|NR4A1	NR4A1 + RPS6KA3_p → RPS6KA3_p \|NR4A1	V(196) = K(196,1) * [RPS6KA3_p] * [NR4A1] -K(196,2) * [RPS6KA3_p \|NR4A1];
R197	RPS6KA3_p \|NR4A1	NR4A1_p + RPS6KA3_p	RPS6KA3_p \|NR4A1 → NR4A1_p + RPS6KA3_p	V(197) = K(197,1) * [RPS6KA3_p \|NR4A1];
R198	AKT1_p + IRAK1	AKT1_p \|IRAK1	AKT1_p + IRAK1 → AKT1_p \|IRAK1	V(198) = K(198,1) * [AKT1_p] * [IRAK1] -K(198,2) * [AKT1_p \|IRAK1];
R199	AKT1_p \|IRAK1	AKT1_p + IRAK1_p	AKT1_p \|IRAK1 → AKT1_p + IRAK1_p	V(199) = K(199,1) * [AKT1_p \|IRAK1];

Reaction ID	Reactants	Products	Original Text	ODE Equations
R1	SP1_p + STAT3_p	SIGNOR-C74	SP1_p + STAT3_p → SIGNOR-C74	V(1) = K(1,1) * [STAT3_p] * [SP1_p] -K(1,2) * [SIGNOR-C74];
R2	STAT1_p + STAT3_p	SIGNOR-C118	STAT1_p + STAT3_p → SIGNOR-C118	V(2) = K(2,1) * [STAT1_p] * [STAT3_p] -K(2,2) * [SIGNOR-C118];
R3	JAK1_p + SIGNOR-C118_p	SIGNOR-C120	JAK1_p + SIGNOR-C118_p → SIGNOR-C120	V(3) = K(3,1) * [SIGNOR-C118_p] * [JAK1_p] -K(3,2) * [SIGNOR-C120];
R4	FOS_p + FOS_p + FOS_p + FOS_p + JUN_p + JUN_p + JUN_p + JUN_p	SIGNOR-C154	FOS_p + FOS_p + FOS_p + FOS_p + JUN_p + JUN_p + JUN_p + JUN_p → SIGNOR-C154	V(4) = K(4,1) * [FOS_p] * [JUN_p] * [JUN_p] * [FOS_p] * [JUN_p] * [FOS_p] * [FOS_p] * [JUN_p] -K(4,2) * [SIGNOR-C154];
R5	PIK3CA + PIK3R1_p	SIGNOR-C156	PIK3CA + PIK3R1_p → SIGNOR-C156	V(5) = K(5,1) * [PIK3R1_p] * [PIK3CA] -K(5,2) * [SIGNOR-C156];
R6	SMAD2 + TGFBR1	TGFBR1 \|SMAD2	SMAD2 + TGFBR1 → TGFBR1 \|SMAD2	V(6) = K(6,1) * [TGFBR1] * [SMAD2] -K(6,2) * [TGFBR1 \|SMAD2];
R7	TGFBR1 \|SMAD2	SMAD2_p + TGFBR1	TGFBR1 \|SMAD2 → SMAD2_p + TGFBR1	V(7) = K(7,1) * [TGFBR1 \|SMAD2];
R8	EP300 + MAPK1_p	MAPK1_p \|EP300	EP300 + MAPK1_p → MAPK1_p \|EP300	V(8) = K(8,1) * [MAPK1_p] * [EP300] -K(8,2) * [MAPK1_p \|EP300];
R9	MAPK1_p \|EP300	EP300_p + MAPK1_p	MAPK1_p \|EP300 → EP300_p + MAPK1_p	V(9) = K(9,1) * [MAPK1_p \|EP300];
R10	HIF1A + MAPK1_p	MAPK1_p \|HIF1A	HIF1A + MAPK1_p → MAPK1_p \|HIF1A	V(10) = K(10,1) * [MAPK1_p] * [HIF1A] -K(10,2) * [MAPK1_p \|HIF1A];
R11	MAPK1_p \|HIF1A	HIF1A_p + MAPK1_p	MAPK1_p \|HIF1A → HIF1A_p + MAPK1_p	V(11) = K(11,1) * [MAPK1_p \|HIF1A];
R12	MAPK1_p + RPS6KA3	MAPK1_p \|RPS6KA3	MAPK1_p + RPS6KA3 → MAPK1_p \|RPS6KA3	V(12) = K(12,1) * [MAPK1_p] * [RPS6KA3] -K(12,2) * [MAPK1_p \|RPS6KA3];
R13	MAPK1_p \|RPS6KA3	MAPK1_p + RPS6KA3_p	MAPK1_p \|RPS6KA3 → MAPK1_p + RPS6KA3_p	V(13) = K(13,1) * [MAPK1_p \|RPS6KA3];
R14	MAPK1_p + PRDX6	MAPK1_p \|PRDX6	MAPK1_p + PRDX6 → MAPK1_p \|PRDX6	V(14) = K(14,1) * [MAPK1_p] * [PRDX6] -K(14,2) * [MAPK1_p \|PRDX6];
R15	MAPK1_p \|PRDX6	MAPK1_p + PRDX6_p	MAPK1_p \|PRDX6 → MAPK1_p + PRDX6_p	V(15) = K(15,1) * [MAPK1_p \|PRDX6];
R16	FYN_p + STK11	FYN_p \|STK11	FYN_p + STK11 → FYN_p \|STK11	V(16) = K(16,1) * [FYN_p] * [STK11] -K(16,2) * [FYN_p \|STK11];
R17	FYN_p \|STK11	FYN_p + STK11_p	FYN_p \|STK11 → FYN_p + STK11_p	V(17) = K(17,1) * [FYN_p \|STK11];
R18	JAK2_p + STAT5A	JAK2_p \|STAT5A	JAK2_p + STAT5A → JAK2_p \|STAT5A	V(18) = K(18,1) * [JAK2_p] * [STAT5A] -K(18,2) * [JAK2_p \|STAT5A];
R19	JAK2_p \|STAT5A	JAK2_p + STAT5A_p	JAK2_p \|STAT5A → JAK2_p + STAT5A_p	V(19) = K(19,1) * [JAK2_p \|STAT5A];
R20	AKT1_p + MDM2	AKT1_p \|MDM2	AKT1_p + MDM2 → AKT1_p \|MDM2	V(20) = K(20,1) * [AKT1_p] * [MDM2] -K(20,2) * [AKT1_p \|MDM2];
R21	AKT1_p \|MDM2	AKT1_p + MDM2_p	AKT1_p \|MDM2 → AKT1_p + MDM2_p	V(21) = K(21,1) * [AKT1_p \|MDM2];
R22	CTLA4 + JAK2_p	JAK2_p \|CTLA4	CTLA4 + JAK2_p → JAK2_p \|CTLA4	V(22) = K(22,1) * [JAK2_p] * [CTLA4] -K(22,2) * [JAK2_p \|CTLA4];
R23	JAK2_p \|CTLA4	CTLA4_p + JAK2_p	JAK2_p \|CTLA4 → CTLA4_p + JAK2_p	V(23) = K(23,1) * [JAK2_p \|CTLA4];
R24	IKBKB + IKBKB_p	IKBKB_p \|IKBKB	IKBKB + IKBKB_p → IKBKB_p \|IKBKB	V(24) = K(24,1) * [IKBKB_p] * [IKBKB] -K(24,2) * [IKBKB_p \|IKBKB];
R25	IKBKB_p \|IKBKB	IKBKB_p + IKBKB_p	IKBKB_p \|IKBKB → IKBKB_p + IKBKB_p	V(25) = K(25,1) * [IKBKB_p \|IKBKB];
R26	JAK2 + JAK2_p	JAK2_p \|JAK2	JAK2 + JAK2_p → JAK2_p \|JAK2	V(26) = K(26,1) * [JAK2_p] * [JAK2] -K(26,2) * [JAK2_p \|JAK2];
R27	JAK2_p \|JAK2	JAK2_p + JAK2_p	JAK2_p \|JAK2 → JAK2_p + JAK2_p	V(27) = K(27,1) * [JAK2_p \|JAK2];
R28	DNM1L + ROCK1	ROCK1 \|DNM1L	DNM1L + ROCK1 → ROCK1 \|DNM1L	V(28) = K(28,1) * [ROCK1] * [DNM1L] -K(28,2) * [ROCK1 \|DNM1L];
R29	ROCK1 \|DNM1L	DNM1L_p + ROCK1	ROCK1 \|DNM1L → DNM1L_p + ROCK1	V(29) = K(29,1) * [ROCK1 \|DNM1L];
R30	MAPK1_p + STK11	MAPK1_p \|STK11	MAPK1_p + STK11 → MAPK1_p \|STK11	V(30) = K(30,1) * [MAPK1_p] * [STK11] -K(30,2) * [MAPK1_p \|STK11];
R31	MAPK1_p \|STK11	MAPK1_p + STK11_p	MAPK1_p \|STK11 → MAPK1_p + STK11_p	V(31) = K(31,1) * [MAPK1_p \|STK11];
R32	JUN + MAPK1_p	MAPK1_p \|JUN	JUN + MAPK1_p → MAPK1_p \|JUN	V(32) = K(32,1) * [MAPK1_p] * [JUN] -K(32,2) * [MAPK1_p \|JUN];
R33	MAPK1_p \|JUN	JUN_p + MAPK1_p	MAPK1_p \|JUN → JUN_p + MAPK1_p	V(33) = K(33,1) * [MAPK1_p \|JUN];
R34	BTK + SIGNOR-C156_p	SIGNOR-C156_p \|BTK	BTK + SIGNOR-C156_p → SIGNOR-C156_p \|BTK	V(34) = K(34,1) * [SIGNOR-C156_p] * [BTK] -K(34,2) * [SIGNOR-C156_p \|BTK];
R35	SIGNOR-C156_p \|BTK	BTK_p + SIGNOR-C156_p	SIGNOR-C156_p \|BTK → BTK_p + SIGNOR-C156_p	V(35) = K(35,1) * [SIGNOR-C156_p \|BTK];
R36	IKBKB + PDPK1_p	PDPK1_p \|IKBKB	IKBKB + PDPK1_p → PDPK1_p \|IKBKB	V(36) = K(36,1) * [PDPK1_p] * [IKBKB] -K(36,2) * [PDPK1_p \|IKBKB];
R37	PDPK1_p \|IKBKB	IKBKB_p + PDPK1_p	PDPK1_p \|IKBKB → IKBKB_p + PDPK1_p	V(37) = K(37,1) * [PDPK1_p \|IKBKB];
R38	CTLA4 + FYN_p	FYN_p \|CTLA4	CTLA4 + FYN_p → FYN_p \|CTLA4	V(38) = K(38,1) * [FYN_p] * [CTLA4] -K(38,2) * [FYN_p \|CTLA4];
R39	FYN_p \|CTLA4	CTLA4_p + FYN_p	FYN_p \|CTLA4 → CTLA4_p + FYN_p	V(39) = K(39,1) * [FYN_p \|CTLA4];
R40	AKT1_p + NR4A1	AKT1_p \|NR4A1	AKT1_p + NR4A1 → AKT1_p \|NR4A1	V(40) = K(40,1) * [AKT1_p] * [NR4A1] -K(40,2) * [AKT1_p \|NR4A1];
R41	AKT1_p \|NR4A1	AKT1_p + NR4A1_p	AKT1_p \|NR4A1 → AKT1_p + NR4A1_p	V(41) = K(41,1) * [AKT1_p \|NR4A1];
R42	JAK2_p + MAP3K5	JAK2_p \|MAP3K5	JAK2_p + MAP3K5 → JAK2_p \|MAP3K5	V(42) = K(42,1) * [JAK2_p] * [MAP3K5] -K(42,2) * [JAK2_p \|MAP3K5];
R43	JAK2_p \|MAP3K5	JAK2_p + MAP3K5_p	JAK2_p \|MAP3K5 → JAK2_p + MAP3K5_p	V(43) = K(43,1) * [JAK2_p \|MAP3K5];
R44	FOS + MAPK1_p	MAPK1_p \|FOS	FOS + MAPK1_p → MAPK1_p \|FOS	V(44) = K(44,1) * [MAPK1_p] * [FOS] -K(44,2) * [MAPK1_p \|FOS];
R45	MAPK1_p \|FOS	FOS_p + MAPK1_p	MAPK1_p \|FOS → FOS_p + MAPK1_p	V(45) = K(45,1) * [MAPK1_p \|FOS];
R46	STK11 + STK11_p	STK11_p \|STK11	STK11 + STK11_p → STK11_p \|STK11	V(46) = K(46,1) * [STK11_p] * [STK11] -K(46,2) * [STK11_p \|STK11];
R47	STK11_p \|STK11	STK11_p + STK11_p	STK11_p \|STK11 → STK11_p + STK11_p	V(47) = K(47,1) * [STK11_p \|STK11];
R48	CTNNB1 + JAK3_p	JAK3_p \|CTNNB1	CTNNB1 + JAK3_p → JAK3_p \|CTNNB1	V(48) = K(48,1) * [JAK3_p] * [CTNNB1] -K(48,2) * [JAK3_p \|CTNNB1];
R49	JAK3_p \|CTNNB1	CTNNB1_p + JAK3_p	JAK3_p \|CTNNB1 → CTNNB1_p + JAK3_p	V(49) = K(49,1) * [JAK3_p \|CTNNB1];
R50	FYN_p + PTPN6	FYN_p \|PTPN6	FYN_p + PTPN6 → FYN_p \|PTPN6	V(50) = K(50,1) * [FYN_p] * [PTPN6] -K(50,2) * [FYN_p \|PTPN6];
R51	FYN_p \|PTPN6	FYN_p + PTPN6_p	FYN_p \|PTPN6 → FYN_p + PTPN6_p	V(51) = K(51,1) * [FYN_p \|PTPN6];
R52	MAPK9_p + TP53	MAPK9_p \|TP53	MAPK9_p + TP53 → MAPK9_p \|TP53	V(52) = K(52,1) * [MAPK9_p] * [TP53] -K(52,2) * [MAPK9_p \|TP53];
R53	MAPK9_p \|TP53	MAPK9_p + TP53_p	MAPK9_p \|TP53 → MAPK9_p + TP53_p	V(53) = K(53,1) * [MAPK9_p \|TP53];
R54	MAPK1_p + SMAD2	MAPK1_p \|SMAD2	MAPK1_p + SMAD2 → MAPK1_p \|SMAD2	V(54) = K(54,1) * [MAPK1_p] * [SMAD2] -K(54,2) * [MAPK1_p \|SMAD2];
R55	MAPK1_p \|SMAD2	MAPK1_p + SMAD2_p	MAPK1_p \|SMAD2 → MAPK1_p + SMAD2_p	V(55) = K(55,1) * [MAPK1_p \|SMAD2];
R56	CTNNB1 + KIT_p	KIT_p \|CTNNB1	CTNNB1 + KIT_p → KIT_p \|CTNNB1	V(56) = K(56,1) * [KIT_p] * [CTNNB1] -K(56,2) * [KIT_p \|CTNNB1];
R57	KIT_p \|CTNNB1	CTNNB1_p + KIT_p	KIT_p \|CTNNB1 → CTNNB1_p + KIT_p	V(57) = K(57,1) * [KIT_p \|CTNNB1];
R58	JUN + MAPK9_p	MAPK9_p \|JUN	JUN + MAPK9_p → MAPK9_p \|JUN	V(58) = K(58,1) * [MAPK9_p] * [JUN] -K(58,2) * [MAPK9_p \|JUN];
R59	MAPK9_p \|JUN	JUN_p + MAPK9_p	MAPK9_p \|JUN → JUN_p + MAPK9_p	V(59) = K(59,1) * [MAPK9_p \|JUN];
R60	BCL2 + MAPK1_p	MAPK1_p \|BCL2	BCL2 + MAPK1_p → MAPK1_p \|BCL2	V(60) = K(60,1) * [MAPK1_p] * [BCL2] -K(60,2) * [MAPK1_p \|BCL2];
R61	MAPK1_p \|BCL2	BCL2_p + MAPK1_p	MAPK1_p \|BCL2 → BCL2_p + MAPK1_p	V(61) = K(61,1) * [MAPK1_p \|BCL2];
R62	INSR + INSR_p	INSR_p \|INSR	INSR + INSR_p → INSR_p \|INSR	V(62) = K(62,1) * [INSR_p] * [INSR] -K(62,2) * [INSR_p \|INSR];
R63	INSR_p \|INSR	INSR_p + INSR_p	INSR_p \|INSR → INSR_p + INSR_p	V(63) = K(63,1) * [INSR_p \|INSR];
R64	AKT1_p + BAD	AKT1_p \|BAD	AKT1_p + BAD → AKT1_p \|BAD	V(64) = K(64,1) * [AKT1_p] * [BAD] -K(64,2) * [AKT1_p \|BAD];
R65	AKT1_p \|BAD	AKT1_p + BAD_p	AKT1_p \|BAD → AKT1_p + BAD_p	V(65) = K(65,1) * [AKT1_p \|BAD];
R66	MAPK1_p + NCF1	MAPK1_p \|NCF1	MAPK1_p + NCF1 → MAPK1_p \|NCF1	V(66) = K(66,1) * [MAPK1_p] * [NCF1] -K(66,2) * [MAPK1_p \|NCF1];
R67	MAPK1_p \|NCF1	MAPK1_p + NCF1_p	MAPK1_p \|NCF1 → MAPK1_p + NCF1_p	V(67) = K(67,1) * [MAPK1_p \|NCF1];
R68	JAK1_p + STAT1	JAK1_p \|STAT1	JAK1_p + STAT1 → JAK1_p \|STAT1	V(68) = K(68,1) * [JAK1_p] * [STAT1] -K(68,2) * [JAK1_p \|STAT1];
R69	JAK1_p \|STAT1	JAK1_p + STAT1_p	JAK1_p \|STAT1 → JAK1_p + STAT1_p	V(69) = K(69,1) * [JAK1_p \|STAT1];
R70	DUSP1 + MAPK1_p	MAPK1_p \|DUSP1	DUSP1 + MAPK1_p → MAPK1_p \|DUSP1	V(70) = K(70,1) * [MAPK1_p] * [DUSP1] -K(70,2) * [MAPK1_p \|DUSP1];
R71	MAPK1_p \|DUSP1	DUSP1_p + MAPK1_p	MAPK1_p \|DUSP1 → DUSP1_p + MAPK1_p	V(71) = K(71,1) * [MAPK1_p \|DUSP1];
R72	AKT1_p + NCF1	AKT1_p \|NCF1	AKT1_p + NCF1 → AKT1_p \|NCF1	V(72) = K(72,1) * [AKT1_p] * [NCF1] -K(72,2) * [AKT1_p \|NCF1];
R73	AKT1_p \|NCF1	AKT1_p + NCF1_p	AKT1_p \|NCF1 → AKT1_p + NCF1_p	V(73) = K(73,1) * [AKT1_p \|NCF1];
R74	PKN1 + PKN1_p	PKN1_p \|PKN1	PKN1 + PKN1_p → PKN1_p \|PKN1	V(74) = K(74,1) * [PKN1_p] * [PKN1] -K(74,2) * [PKN1_p \|PKN1];
R75	PKN1_p \|PKN1	PKN1_p + PKN1_p	PKN1_p \|PKN1 → PKN1_p + PKN1_p	V(75) = K(75,1) * [PKN1_p \|PKN1];
R76	AKT1_p + CDKN1A	AKT1_p \|CDKN1A	AKT1_p + CDKN1A → AKT1_p \|CDKN1A	V(76) = K(76,1) * [AKT1_p] * [CDKN1A] -K(76,2) * [AKT1_p \|CDKN1A];
R77	AKT1_p \|CDKN1A	AKT1_p + CDKN1A_p	AKT1_p \|CDKN1A → AKT1_p + CDKN1A_p	V(77) = K(77,1) * [AKT1_p \|CDKN1A];
R78	JAK3_p + STAT5A	JAK3_p \|STAT5A	JAK3_p + STAT5A → JAK3_p \|STAT5A	V(78) = K(78,1) * [JAK3_p] * [STAT5A] -K(78,2) * [JAK3_p \|STAT5A];
R79	JAK3_p \|STAT5A	JAK3_p + STAT5A_p	JAK3_p \|STAT5A → JAK3_p + STAT5A_p	V(79) = K(79,1) * [JAK3_p \|STAT5A];
R80	JAK1 + JAK3_p	JAK3_p \|JAK1	JAK1 + JAK3_p → JAK3_p \|JAK1	V(80) = K(80,1) * [JAK3_p] * [JAK1] -K(80,2) * [JAK3_p \|JAK1];
R81	JAK3_p \|JAK1	JAK1_p + JAK3_p	JAK3_p \|JAK1 → JAK1_p + JAK3_p	V(81) = K(81,1) * [JAK3_p \|JAK1];
R82	KIT + KIT_p	KIT_p \|KIT	KIT + KIT_p → KIT_p \|KIT	V(82) = K(82,1) * [KIT_p] * [KIT] -K(82,2) * [KIT_p \|KIT];
R83	KIT_p \|KIT	KIT_p + KIT_p	KIT_p \|KIT → KIT_p + KIT_p	V(83) = K(83,1) * [KIT_p \|KIT];
R84	INSR_p + SIGNOR-C156	INSR_p \|SIGNOR-C156	INSR_p + SIGNOR-C156 → INSR_p \|SIGNOR-C156	V(84) = K(84,1) * [INSR_p] * [SIGNOR-C156] -K(84,2) * [INSR_p \|SIGNOR-C156];
R85	INSR_p \|SIGNOR-C156	INSR_p + SIGNOR-C156_p	INSR_p \|SIGNOR-C156 → INSR_p + SIGNOR-C156_p	V(85) = K(85,1) * [INSR_p \|SIGNOR-C156];
R86	MAPK1_p + RHOA	MAPK1_p \|RHOA	MAPK1_p + RHOA → MAPK1_p \|RHOA	V(86) = K(86,1) * [MAPK1_p] * [RHOA] -K(86,2) * [MAPK1_p \|RHOA];
R87	MAPK1_p \|RHOA	MAPK1_p + RHOA_p	MAPK1_p \|RHOA → MAPK1_p + RHOA_p	V(87) = K(87,1) * [MAPK1_p \|RHOA];
R88	EPOR + JAK2_p	JAK2_p \|EPOR	EPOR + JAK2_p → JAK2_p \|EPOR	V(88) = K(88,1) * [JAK2_p] * [EPOR] -K(88,2) * [JAK2_p \|EPOR];
R89	JAK2_p \|EPOR	EPOR_p + JAK2_p	JAK2_p \|EPOR → EPOR_p + JAK2_p	V(89) = K(89,1) * [JAK2_p \|EPOR];
R90	AKT1_p + PPARGC1A	AKT1_p \|PPARGC1A	AKT1_p + PPARGC1A → AKT1_p \|PPARGC1A	V(90) = K(90,1) * [AKT1_p] * [PPARGC1A] -K(90,2) * [AKT1_p \|PPARGC1A];
R91	AKT1_p \|PPARGC1A	AKT1_p + PPARGC1A_p	AKT1_p \|PPARGC1A → AKT1_p + PPARGC1A_p	V(91) = K(91,1) * [AKT1_p \|PPARGC1A];
R92	ATR + PARP1	ATR \|PARP1	ATR + PARP1 → ATR \|PARP1	V(92) = K(92,1) * [ATR] * [PARP1] -K(92,2) * [ATR \|PARP1];
R93	ATR \|PARP1	ATR + PARP1_p	ATR \|PARP1 → ATR + PARP1_p	V(93) = K(93,1) * [ATR \|PARP1];
R94	JAK2_p + STAT1	JAK2_p \|STAT1	JAK2_p + STAT1 → JAK2_p \|STAT1	V(94) = K(94,1) * [JAK2_p] * [STAT1] -K(94,2) * [JAK2_p \|STAT1];
R95	JAK2_p \|STAT1	JAK2_p + STAT1_p	JAK2_p \|STAT1 → JAK2_p + STAT1_p	V(95) = K(95,1) * [JAK2_p \|STAT1];
R96	MAPK1_p + TFEB	MAPK1_p \|TFEB	MAPK1_p + TFEB → MAPK1_p \|TFEB	V(96) = K(96,1) * [MAPK1_p] * [TFEB] -K(96,2) * [MAPK1_p \|TFEB];
R97	MAPK1_p \|TFEB	MAPK1_p + TFEB_p	MAPK1_p \|TFEB → MAPK1_p + TFEB_p	V(97) = K(97,1) * [MAPK1_p \|TFEB];
R98	PDPK1_p + SGK1	PDPK1_p \|SGK1	PDPK1_p + SGK1 → PDPK1_p \|SGK1	V(98) = K(98,1) * [PDPK1_p] * [SGK1] -K(98,2) * [PDPK1_p \|SGK1];
R99	PDPK1_p \|SGK1	PDPK1_p + SGK1_p	PDPK1_p \|SGK1 → PDPK1_p + SGK1_p	V(99) = K(99,1) * [PDPK1_p \|SGK1];
R100	ERN1 + ERN1_p	ERN1_p \|ERN1	ERN1 + ERN1_p → ERN1_p \|ERN1	V(100) = K(100,1) * [ERN1_p] * [ERN1] -K(100,2) * [ERN1_p \|ERN1];
R101	ERN1_p \|ERN1	ERN1_p + ERN1_p	ERN1_p \|ERN1 → ERN1_p + ERN1_p	V(101) = K(101,1) * [ERN1_p \|ERN1];
R102	DEPTOR + RPS6KA3_p	RPS6KA3_p \|DEPTOR	DEPTOR + RPS6KA3_p → RPS6KA3_p \|DEPTOR	V(102) = K(102,1) * [RPS6KA3_p] * [DEPTOR] -K(102,2) * [RPS6KA3_p \|DEPTOR];
R103	RPS6KA3_p \|DEPTOR	DEPTOR_p + RPS6KA3_p	RPS6KA3_p \|DEPTOR → DEPTOR_p + RPS6KA3_p	V(103) = K(103,1) * [RPS6KA3_p \|DEPTOR];
R104	MAP3K5 + RPS6KA3_p	RPS6KA3_p \|MAP3K5	MAP3K5 + RPS6KA3_p → RPS6KA3_p \|MAP3K5	V(104) = K(104,1) * [RPS6KA3_p] * [MAP3K5] -K(104,2) * [RPS6KA3_p \|MAP3K5];
R105	RPS6KA3_p \|MAP3K5	MAP3K5_p + RPS6KA3_p	RPS6KA3_p \|MAP3K5 → MAP3K5_p + RPS6KA3_p	V(105) = K(105,1) * [RPS6KA3_p \|MAP3K5];
R106	ATR + MDM2	ATR \|MDM2	ATR + MDM2 → ATR \|MDM2	V(106) = K(106,1) * [ATR] * [MDM2] -K(106,2) * [ATR \|MDM2];
R107	ATR \|MDM2	ATR + MDM2_p	ATR \|MDM2 → ATR + MDM2_p	V(107) = K(107,1) * [ATR \|MDM2];
R108	MAPK1_p + SIGNOR-C154	MAPK1_p \|SIGNOR-C154	MAPK1_p + SIGNOR-C154 → MAPK1_p \|SIGNOR-C154	V(108) = K(108,1) * [MAPK1_p] * [SIGNOR-C154] -K(108,2) * [MAPK1_p \|SIGNOR-C154];
R109	MAPK1_p \|SIGNOR-C154	MAPK1_p + SIGNOR-C154_p	MAPK1_p \|SIGNOR-C154 → MAPK1_p + SIGNOR-C154_p	V(109) = K(109,1) * [MAPK1_p \|SIGNOR-C154];
R110	BAD + RPS6KA3_p	RPS6KA3_p \|BAD	BAD + RPS6KA3_p → RPS6KA3_p \|BAD	V(110) = K(110,1) * [RPS6KA3_p] * [BAD] -K(110,2) * [RPS6KA3_p \|BAD];
R111	RPS6KA3_p \|BAD	BAD_p + RPS6KA3_p	RPS6KA3_p \|BAD → BAD_p + RPS6KA3_p	V(111) = K(111,1) * [RPS6KA3_p \|BAD];
R112	CTNNB1 + MAPK9_p	MAPK9_p \|CTNNB1	CTNNB1 + MAPK9_p → MAPK9_p \|CTNNB1	V(112) = K(112,1) * [MAPK9_p] * [CTNNB1] -K(112,2) * [MAPK9_p \|CTNNB1];
R113	MAPK9_p \|CTNNB1	CTNNB1_p + MAPK9_p	MAPK9_p \|CTNNB1 → CTNNB1_p + MAPK9_p	V(113) = K(113,1) * [MAPK9_p \|CTNNB1];
R114	PINK1 + UBC	PINK1 \|UBC	PINK1 + UBC → PINK1 \|UBC	V(114) = K(114,1) * [PINK1] * [UBC] -K(114,2) * [PINK1 \|UBC];
R115	PINK1 \|UBC	PINK1 + UBC_p	PINK1 \|UBC → PINK1 + UBC_p	V(115) = K(115,1) * [PINK1 \|UBC];
R116	AKT1_p + RAC1	AKT1_p \|RAC1	AKT1_p + RAC1 → AKT1_p \|RAC1	V(116) = K(116,1) * [AKT1_p] * [RAC1] -K(116,2) * [AKT1_p \|RAC1];
R117	AKT1_p \|RAC1	AKT1_p + RAC1_p	AKT1_p \|RAC1 → AKT1_p + RAC1_p	V(117) = K(117,1) * [AKT1_p \|RAC1];
R118	AKT1 + PDPK1_p	PDPK1_p \|AKT1	AKT1 + PDPK1_p → PDPK1_p \|AKT1	V(118) = K(118,1) * [PDPK1_p] * [AKT1] -K(118,2) * [PDPK1_p \|AKT1];
R119	PDPK1_p \|AKT1	AKT1_p + PDPK1_p	PDPK1_p \|AKT1 → AKT1_p + PDPK1_p	V(119) = K(119,1) * [PDPK1_p \|AKT1];
R120	STK4 + STK4_p	STK4_p \|STK4	STK4 + STK4_p → STK4_p \|STK4	V(120) = K(120,1) * [STK4_p] * [STK4] -K(120,2) * [STK4_p \|STK4];
R121	STK4_p \|STK4	STK4_p + STK4_p	STK4_p \|STK4 → STK4_p + STK4_p	V(121) = K(121,1) * [STK4_p \|STK4];
R122	PTEN + STK11_p	STK11_p \|PTEN	PTEN + STK11_p → STK11_p \|PTEN	V(122) = K(122,1) * [STK11_p] * [PTEN] -K(122,2) * [STK11_p \|PTEN];
R123	STK11_p \|PTEN	PTEN_p + STK11_p	STK11_p \|PTEN → PTEN_p + STK11_p	V(123) = K(123,1) * [STK11_p \|PTEN];
R124	HIPK2 + HIPK2_p	HIPK2_p \|HIPK2	HIPK2 + HIPK2_p → HIPK2_p \|HIPK2	V(124) = K(124,1) * [HIPK2_p] * [HIPK2] -K(124,2) * [HIPK2_p \|HIPK2];
R125	HIPK2_p \|HIPK2	HIPK2_p + HIPK2_p	HIPK2_p \|HIPK2 → HIPK2_p + HIPK2_p	V(125) = K(125,1) * [HIPK2_p \|HIPK2];
R126	BECN1 + JAK2_p	JAK2_p \|BECN1	BECN1 + JAK2_p → JAK2_p \|BECN1	V(126) = K(126,1) * [JAK2_p] * [BECN1] -K(126,2) * [JAK2_p \|BECN1];
R127	JAK2_p \|BECN1	BECN1_p + JAK2_p	JAK2_p \|BECN1 → BECN1_p + JAK2_p	V(127) = K(127,1) * [JAK2_p \|BECN1];
R128	PDPK1 + PDPK1_p	PDPK1_p \|PDPK1	PDPK1 + PDPK1_p → PDPK1_p \|PDPK1	V(128) = K(128,1) * [PDPK1_p] * [PDPK1] -K(128,2) * [PDPK1_p \|PDPK1];
R129	PDPK1_p \|PDPK1	PDPK1_p + PDPK1_p	PDPK1_p \|PDPK1 → PDPK1_p + PDPK1_p	V(129) = K(129,1) * [PDPK1_p \|PDPK1];
R130	AKT1_p + EP300	AKT1_p \|EP300	AKT1_p + EP300 → AKT1_p \|EP300	V(130) = K(130,1) * [AKT1_p] * [EP300] -K(130,2) * [AKT1_p \|EP300];
R131	AKT1_p \|EP300	AKT1_p + EP300_p	AKT1_p \|EP300 → AKT1_p + EP300_p	V(131) = K(131,1) * [AKT1_p \|EP300];
R132	FYN + FYN_p	FYN_p \|FYN	FYN + FYN_p → FYN_p \|FYN	V(132) = K(132,1) * [FYN_p] * [FYN] -K(132,2) * [FYN_p \|FYN];
R133	FYN_p \|FYN	FYN_p + FYN_p	FYN_p \|FYN → FYN_p + FYN_p	V(133) = K(133,1) * [FYN_p \|FYN];
R134	IRAK1 + IRAK1_p	IRAK1_p \|IRAK1	IRAK1 + IRAK1_p → IRAK1_p \|IRAK1	V(134) = K(134,1) * [IRAK1_p] * [IRAK1] -K(134,2) * [IRAK1_p \|IRAK1];
R135	IRAK1_p \|IRAK1	IRAK1_p + IRAK1_p	IRAK1_p \|IRAK1 → IRAK1_p + IRAK1_p	V(135) = K(135,1) * [IRAK1_p \|IRAK1];
R136	BAD + SIGNOR-C156_p	SIGNOR-C156_p \|BAD	BAD + SIGNOR-C156_p → SIGNOR-C156_p \|BAD	V(136) = K(136,1) * [SIGNOR-C156_p] * [BAD] -K(136,2) * [SIGNOR-C156_p \|BAD];
R137	SIGNOR-C156_p \|BAD	BAD_p + SIGNOR-C156_p	SIGNOR-C156_p \|BAD → BAD_p + SIGNOR-C156_p	V(137) = K(137,1) * [SIGNOR-C156_p \|BAD];
R138	MAP3K5 + MAP3K5_p	MAP3K5_p \|MAP3K5	MAP3K5 + MAP3K5_p → MAP3K5_p \|MAP3K5	V(138) = K(138,1) * [MAP3K5_p] * [MAP3K5] -K(138,2) * [MAP3K5_p \|MAP3K5];
R139	MAP3K5_p \|MAP3K5	MAP3K5_p + MAP3K5_p	MAP3K5_p \|MAP3K5 → MAP3K5_p + MAP3K5_p	V(139) = K(139,1) * [MAP3K5_p \|MAP3K5];
R140	IKBKB_p + NFKB1	IKBKB_p \|NFKB1	IKBKB_p + NFKB1 → IKBKB_p \|NFKB1	V(140) = K(140,1) * [IKBKB_p] * [NFKB1] -K(140,2) * [IKBKB_p \|NFKB1];
R141	IKBKB_p \|NFKB1	IKBKB_p + NFKB1_p	IKBKB_p \|NFKB1 → IKBKB_p + NFKB1_p	V(141) = K(141,1) * [IKBKB_p \|NFKB1];
R142	AKT1 + ILK_p	ILK_p \|AKT1	AKT1 + ILK_p → ILK_p \|AKT1	V(142) = K(142,1) * [ILK_p] * [AKT1] -K(142,2) * [ILK_p \|AKT1];
R143	ILK_p \|AKT1	AKT1_p + ILK_p	ILK_p \|AKT1 → AKT1_p + ILK_p	V(143) = K(143,1) * [ILK_p \|AKT1];
R144	AKT1_p + BTK	AKT1_p \|BTK	AKT1_p + BTK → AKT1_p \|BTK	V(144) = K(144,1) * [AKT1_p] * [BTK] -K(144,2) * [AKT1_p \|BTK];
R145	AKT1_p \|BTK	AKT1_p + BTK_p	AKT1_p \|BTK → AKT1_p + BTK_p	V(145) = K(145,1) * [AKT1_p \|BTK];
R146	MAPK1_p + SP1	MAPK1_p \|SP1	MAPK1_p + SP1 → MAPK1_p \|SP1	V(146) = K(146,1) * [MAPK1_p] * [SP1] -K(146,2) * [MAPK1_p \|SP1];
R147	MAPK1_p \|SP1	MAPK1_p + SP1_p	MAPK1_p \|SP1 → MAPK1_p + SP1_p	V(147) = K(147,1) * [MAPK1_p \|SP1];
R148	PTEN + ROCK1	ROCK1 \|PTEN	PTEN + ROCK1 → ROCK1 \|PTEN	V(148) = K(148,1) * [ROCK1] * [PTEN] -K(148,2) * [ROCK1 \|PTEN];
R149	ROCK1 \|PTEN	PTEN_p + ROCK1	ROCK1 \|PTEN → PTEN_p + ROCK1	V(149) = K(149,1) * [ROCK1 \|PTEN];
R150	MAPK1_p + STAT5A	MAPK1_p \|STAT5A	MAPK1_p + STAT5A → MAPK1_p \|STAT5A	V(150) = K(150,1) * [MAPK1_p] * [STAT5A] -K(150,2) * [MAPK1_p \|STAT5A];
R151	MAPK1_p \|STAT5A	MAPK1_p + STAT5A_p	MAPK1_p \|STAT5A → MAPK1_p + STAT5A_p	V(151) = K(151,1) * [MAPK1_p \|STAT5A];
R152	BAD + MAPK1_p	MAPK1_p \|BAD	BAD + MAPK1_p → MAPK1_p \|BAD	V(152) = K(152,1) * [MAPK1_p] * [BAD] -K(152,2) * [MAPK1_p \|BAD];
R153	MAPK1_p \|BAD	BAD_p + MAPK1_p	MAPK1_p \|BAD → BAD_p + MAPK1_p	V(153) = K(153,1) * [MAPK1_p \|BAD];
R154	PDPK1_p + RPS6KA3	PDPK1_p \|RPS6KA3	PDPK1_p + RPS6KA3 → PDPK1_p \|RPS6KA3	V(154) = K(154,1) * [PDPK1_p] * [RPS6KA3] -K(154,2) * [PDPK1_p \|RPS6KA3];
R155	PDPK1_p \|RPS6KA3	PDPK1_p + RPS6KA3_p	PDPK1_p \|RPS6KA3 → PDPK1_p + RPS6KA3_p	V(155) = K(155,1) * [PDPK1_p \|RPS6KA3];
R156	CDKN1A + MAPK1_p	MAPK1_p \|CDKN1A	CDKN1A + MAPK1_p → MAPK1_p \|CDKN1A	V(156) = K(156,1) * [MAPK1_p] * [CDKN1A] -K(156,2) * [MAPK1_p \|CDKN1A];
R157	MAPK1_p \|CDKN1A	CDKN1A_p + MAPK1_p	MAPK1_p \|CDKN1A → CDKN1A_p + MAPK1_p	V(157) = K(157,1) * [MAPK1_p \|CDKN1A];
R158	AKT1S1 + AKT1_p	AKT1_p \|AKT1S1	AKT1S1 + AKT1_p → AKT1_p \|AKT1S1	V(158) = K(158,1) * [AKT1_p] * [AKT1S1] -K(158,2) * [AKT1_p \|AKT1S1];
R159	AKT1_p \|AKT1S1	AKT1S1_p + AKT1_p	AKT1_p \|AKT1S1 → AKT1S1_p + AKT1_p	V(159) = K(159,1) * [AKT1_p \|AKT1S1];
R160	JAK3 + JAK3_p	JAK3_p \|JAK3	JAK3 + JAK3_p → JAK3_p \|JAK3	V(160) = K(160,1) * [JAK3_p] * [JAK3] -K(160,2) * [JAK3_p \|JAK3];
R161	JAK3_p \|JAK3	JAK3_p + JAK3_p	JAK3_p \|JAK3 → JAK3_p + JAK3_p	V(161) = K(161,1) * [JAK3_p \|JAK3];
R162	IL6R + JAK2	IL6R \|JAK2	IL6R + JAK2 → IL6R \|JAK2	V(162) = K(162,1) * [IL6R] * [JAK2] -K(162,2) * [IL6R \|JAK2];
R163	IL6R \|JAK2	IL6R + JAK2_p	IL6R \|JAK2 → IL6R + JAK2_p	V(163) = K(163,1) * [IL6R \|JAK2];
R164	JAK2 + MAPK1_p	MAPK1_p \|JAK2	JAK2 + MAPK1_p → MAPK1_p \|JAK2	V(164) = K(164,1) * [MAPK1_p] * [JAK2] -K(164,2) * [MAPK1_p \|JAK2];
R165	MAPK1_p \|JAK2	JAK2_p + MAPK1_p	MAPK1_p \|JAK2 → JAK2_p + MAPK1_p	V(165) = K(165,1) * [MAPK1_p \|JAK2];
R166	JAK1_p + STAT3	JAK1_p \|STAT3	JAK1_p + STAT3 → JAK1_p \|STAT3	V(166) = K(166,1) * [JAK1_p] * [STAT3] -K(166,2) * [JAK1_p \|STAT3];
R167	JAK1_p \|STAT3	JAK1_p + STAT3_p	JAK1_p \|STAT3 → JAK1_p + STAT3_p	V(167) = K(167,1) * [JAK1_p \|STAT3];
R168	MAPK1_p + PARP1	MAPK1_p \|PARP1	MAPK1_p + PARP1 → MAPK1_p \|PARP1	V(168) = K(168,1) * [MAPK1_p] * [PARP1] -K(168,2) * [MAPK1_p \|PARP1];
R169	MAPK1_p \|PARP1	MAPK1_p + PARP1_p	MAPK1_p \|PARP1 → MAPK1_p + PARP1_p	V(169) = K(169,1) * [MAPK1_p \|PARP1];
R170	FYN_p + PTGS2	FYN_p \|PTGS2	FYN_p + PTGS2 → FYN_p \|PTGS2	V(170) = K(170,1) * [FYN_p] * [PTGS2] -K(170,2) * [FYN_p \|PTGS2];
R171	FYN_p \|PTGS2	FYN_p + PTGS2_p	FYN_p \|PTGS2 → FYN_p + PTGS2_p	V(171) = K(171,1) * [FYN_p \|PTGS2];
R172	PIK3CA + STK4_p	STK4_p \|PIK3CA	PIK3CA + STK4_p → STK4_p \|PIK3CA	V(172) = K(172,1) * [STK4_p] * [PIK3CA] -K(172,2) * [STK4_p \|PIK3CA];
R173	STK4_p \|PIK3CA	PIK3CA_p + STK4_p	STK4_p \|PIK3CA → PIK3CA_p + STK4_p	V(173) = K(173,1) * [STK4_p \|PIK3CA];
R174	AKT1 + SIGNOR-C156_p	SIGNOR-C156_p \|AKT1	AKT1 + SIGNOR-C156_p → SIGNOR-C156_p \|AKT1	V(174) = K(174,1) * [SIGNOR-C156_p] * [AKT1] -K(174,2) * [SIGNOR-C156_p \|AKT1];
R175	SIGNOR-C156_p \|AKT1	AKT1_p + SIGNOR-C156_p	SIGNOR-C156_p \|AKT1 → AKT1_p + SIGNOR-C156_p	V(175) = K(175,1) * [SIGNOR-C156_p \|AKT1];
R176	BTK_p + STAT3	BTK_p \|STAT3	BTK_p + STAT3 → BTK_p \|STAT3	V(176) = K(176,1) * [BTK_p] * [STAT3] -K(176,2) * [BTK_p \|STAT3];
R177	BTK_p \|STAT3	BTK_p + STAT3_p	BTK_p \|STAT3 → BTK_p + STAT3_p	V(177) = K(177,1) * [BTK_p \|STAT3];
R178	IRF3 + STK4_p	STK4_p \|IRF3	IRF3 + STK4_p → STK4_p \|IRF3	V(178) = K(178,1) * [STK4_p] * [IRF3] -K(178,2) * [STK4_p \|IRF3];
R179	STK4_p \|IRF3	IRF3_p + STK4_p	STK4_p \|IRF3 → IRF3_p + STK4_p	V(179) = K(179,1) * [STK4_p \|IRF3];
R180	FOS + RPS6KA3_p	RPS6KA3_p \|FOS	FOS + RPS6KA3_p → RPS6KA3_p \|FOS	V(180) = K(180,1) * [RPS6KA3_p] * [FOS] -K(180,2) * [RPS6KA3_p \|FOS];
R181	RPS6KA3_p \|FOS	FOS_p + RPS6KA3_p	RPS6KA3_p \|FOS → FOS_p + RPS6KA3_p	V(181) = K(181,1) * [RPS6KA3_p \|FOS];
R182	AKT1_p + RPS6KA3	AKT1_p \|RPS6KA3	AKT1_p + RPS6KA3 → AKT1_p \|RPS6KA3	V(182) = K(182,1) * [AKT1_p] * [RPS6KA3] -K(182,2) * [AKT1_p \|RPS6KA3];
R183	AKT1_p \|RPS6KA3	AKT1_p + RPS6KA3_p	AKT1_p \|RPS6KA3 → AKT1_p + RPS6KA3_p	V(183) = K(183,1) * [AKT1_p \|RPS6KA3];
R184	KIT_p + STAT1	KIT_p \|STAT1	KIT_p + STAT1 → KIT_p \|STAT1	V(184) = K(184,1) * [KIT_p] * [STAT1] -K(184,2) * [KIT_p \|STAT1];
R185	KIT_p \|STAT1	KIT_p + STAT1_p	KIT_p \|STAT1 → KIT_p + STAT1_p	V(185) = K(185,1) * [KIT_p \|STAT1];
R186	AKT1_p + DNMT1	AKT1_p \|DNMT1	AKT1_p + DNMT1 → AKT1_p \|DNMT1	V(186) = K(186,1) * [AKT1_p] * [DNMT1] -K(186,2) * [AKT1_p \|DNMT1];
R187	AKT1_p \|DNMT1	AKT1_p + DNMT1_p	AKT1_p \|DNMT1 → AKT1_p + DNMT1_p	V(187) = K(187,1) * [AKT1_p \|DNMT1];
R188	SIRT1 + STK11_p	STK11_p \|SIRT1	SIRT1 + STK11_p → STK11_p \|SIRT1	V(188) = K(188,1) * [STK11_p] * [SIRT1] -K(188,2) * [STK11_p \|SIRT1];
R189	STK11_p \|SIRT1	SIRT1_p + STK11_p	STK11_p \|SIRT1 → SIRT1_p + STK11_p	V(189) = K(189,1) * [STK11_p \|SIRT1];
R190	RPS6KA3 + RPS6KA3_p	RPS6KA3_p \|RPS6KA3	RPS6KA3 + RPS6KA3_p → RPS6KA3_p \|RPS6KA3	V(190) = K(190,1) * [RPS6KA3_p] * [RPS6KA3] -K(190,2) * [RPS6KA3_p \|RPS6KA3];
R191	RPS6KA3_p \|RPS6KA3	RPS6KA3_p + RPS6KA3_p	RPS6KA3_p \|RPS6KA3 → RPS6KA3_p + RPS6KA3_p	V(191) = K(191,1) * [RPS6KA3_p \|RPS6KA3];
R192	AKT1_p + CTNNB1	AKT1_p \|CTNNB1	AKT1_p + CTNNB1 → AKT1_p \|CTNNB1	V(192) = K(192,1) * [AKT1_p] * [CTNNB1] -K(192,2) * [AKT1_p \|CTNNB1];
R193	AKT1_p \|CTNNB1	AKT1_p + CTNNB1_p	AKT1_p \|CTNNB1 → AKT1_p + CTNNB1_p	V(193) = K(193,1) * [AKT1_p \|CTNNB1];
R194	AKT1_p + STK4	AKT1_p \|STK4	AKT1_p + STK4 → AKT1_p \|STK4	V(194) = K(194,1) * [AKT1_p] * [STK4] -K(194,2) * [AKT1_p \|STK4];
R195	AKT1_p \|STK4	AKT1_p + STK4_p	AKT1_p \|STK4 → AKT1_p + STK4_p	V(195) = K(195,1) * [AKT1_p \|STK4];
R196	NR4A1 + RPS6KA3_p	RPS6KA3_p \|NR4A1	NR4A1 + RPS6KA3_p → RPS6KA3_p \|NR4A1	V(196) = K(196,1) * [RPS6KA3_p] * [NR4A1] -K(196,2) * [RPS6KA3_p \|NR4A1];
R197	RPS6KA3_p \|NR4A1	NR4A1_p + RPS6KA3_p	RPS6KA3_p \|NR4A1 → NR4A1_p + RPS6KA3_p	V(197) = K(197,1) * [RPS6KA3_p \|NR4A1];
R198	AKT1_p + IRAK1	AKT1_p \|IRAK1	AKT1_p + IRAK1 → AKT1_p \|IRAK1	V(198) = K(198,1) * [AKT1_p] * [IRAK1] -K(198,2) * [AKT1_p \|IRAK1];
R199	AKT1_p \|IRAK1	AKT1_p + IRAK1_p	AKT1_p \|IRAK1 → AKT1_p + IRAK1_p	V(199) = K(199,1) * [AKT1_p \|IRAK1];