Fibroblast Cell_Parametric ODE Equations

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Reaction ID	Reactants	Products	Original Text	ODE Equations
R1	JUN_p + SMAD4_p	SIGNOR-C10	JUN_p + SMAD4_p → SIGNOR-C10	V(1) = K(1,1) * [SMAD4_p] * [JUN_p] -K(1,2) * [SIGNOR-C10];
R2	SP1_p + STAT3_p	SIGNOR-C74	SP1_p + STAT3_p → SIGNOR-C74	V(2) = K(2,1) * [STAT3_p] * [SP1_p] -K(2,2) * [SIGNOR-C74];
R3	STAT1_p + STAT3_p	SIGNOR-C118	STAT1_p + STAT3_p → SIGNOR-C118	V(3) = K(3,1) * [STAT1_p] * [STAT3_p] -K(3,2) * [SIGNOR-C118];
R4	JAK1 + SIGNOR-C118	SIGNOR-C120	JAK1 + SIGNOR-C118 → SIGNOR-C120	V(4) = K(4,1) * [SIGNOR-C118] * [JAK1] -K(4,2) * [SIGNOR-C120];
R5	FOS_p + FOS_p + FOS_p + FOS_p + JUN_p + JUN_p + JUN_p + JUN_p	SIGNOR-C154	FOS_p + FOS_p + FOS_p + FOS_p + JUN_p + JUN_p + JUN_p + JUN_p → SIGNOR-C154	V(5) = K(5,1) * [FOS_p] * [JUN_p] * [JUN_p] * [FOS_p] * [JUN_p] * [FOS_p] * [FOS_p] * [JUN_p] -K(5,2) * [SIGNOR-C154];
R6	PIK3CA + PIK3R1_p	SIGNOR-C156	PIK3CA + PIK3R1_p → SIGNOR-C156	V(6) = K(6,1) * [PIK3R1_p] * [PIK3CA] -K(6,2) * [SIGNOR-C156];
R7	EP300 + MAPK1_p	MAPK1_p \|EP300	EP300 + MAPK1_p → MAPK1_p \|EP300	V(7) = K(7,1) * [MAPK1_p] * [EP300] -K(7,2) * [MAPK1_p \|EP300];
R8	MAPK1_p \|EP300	EP300_p + MAPK1_p	MAPK1_p \|EP300 → EP300_p + MAPK1_p	V(8) = K(8,1) * [MAPK1_p \|EP300];
R9	HIF1A + MAPK1_p	MAPK1_p \|HIF1A	HIF1A + MAPK1_p → MAPK1_p \|HIF1A	V(9) = K(9,1) * [MAPK1_p] * [HIF1A] -K(9,2) * [MAPK1_p \|HIF1A];
R10	MAPK1_p \|HIF1A	HIF1A_p + MAPK1_p	MAPK1_p \|HIF1A → HIF1A_p + MAPK1_p	V(10) = K(10,1) * [MAPK1_p \|HIF1A];
R11	MAPK1_p + NR3C1	MAPK1_p \|NR3C1	MAPK1_p + NR3C1 → MAPK1_p \|NR3C1	V(11) = K(11,1) * [MAPK1_p] * [NR3C1] -K(11,2) * [MAPK1_p \|NR3C1];
R12	MAPK1_p \|NR3C1	MAPK1_p + NR3C1_p	MAPK1_p \|NR3C1 → MAPK1_p + NR3C1_p	V(12) = K(12,1) * [MAPK1_p \|NR3C1];
R13	MAPK1_p + RPS6KA3	MAPK1_p \|RPS6KA3	MAPK1_p + RPS6KA3 → MAPK1_p \|RPS6KA3	V(13) = K(13,1) * [MAPK1_p] * [RPS6KA3] -K(13,2) * [MAPK1_p \|RPS6KA3];
R14	MAPK1_p \|RPS6KA3	MAPK1_p + RPS6KA3_p	MAPK1_p \|RPS6KA3 → MAPK1_p + RPS6KA3_p	V(14) = K(14,1) * [MAPK1_p \|RPS6KA3];
R15	MAPK1_p + PRDX6	MAPK1_p \|PRDX6	MAPK1_p + PRDX6 → MAPK1_p \|PRDX6	V(15) = K(15,1) * [MAPK1_p] * [PRDX6] -K(15,2) * [MAPK1_p \|PRDX6];
R16	MAPK1_p \|PRDX6	MAPK1_p + PRDX6_p	MAPK1_p \|PRDX6 → MAPK1_p + PRDX6_p	V(16) = K(16,1) * [MAPK1_p \|PRDX6];
R17	CTNNB1 + PRKCA_p	PRKCA_p \|CTNNB1	CTNNB1 + PRKCA_p → PRKCA_p \|CTNNB1	V(17) = K(17,1) * [PRKCA_p] * [CTNNB1] -K(17,2) * [PRKCA_p \|CTNNB1];
R18	PRKCA_p \|CTNNB1	CTNNB1_p + PRKCA_p	PRKCA_p \|CTNNB1 → CTNNB1_p + PRKCA_p	V(18) = K(18,1) * [PRKCA_p \|CTNNB1];
R19	AKT1_p + MDM2	AKT1_p \|MDM2	AKT1_p + MDM2 → AKT1_p \|MDM2	V(19) = K(19,1) * [AKT1_p] * [MDM2] -K(19,2) * [AKT1_p \|MDM2];
R20	AKT1_p \|MDM2	AKT1_p + MDM2_p	AKT1_p \|MDM2 → AKT1_p + MDM2_p	V(20) = K(20,1) * [AKT1_p \|MDM2];
R21	AKT1_p + PRKAA1	AKT1_p \|PRKAA1	AKT1_p + PRKAA1 → AKT1_p \|PRKAA1	V(21) = K(21,1) * [AKT1_p] * [PRKAA1] -K(21,2) * [AKT1_p \|PRKAA1];
R22	AKT1_p \|PRKAA1	AKT1_p + PRKAA1_p	AKT1_p \|PRKAA1 → AKT1_p + PRKAA1_p	V(22) = K(22,1) * [AKT1_p \|PRKAA1];
R23	EGFR + EGFR_p	EGFR_p \|EGFR	EGFR + EGFR_p → EGFR_p \|EGFR	V(23) = K(23,1) * [EGFR_p] * [EGFR] -K(23,2) * [EGFR_p \|EGFR];
R24	EGFR_p \|EGFR	EGFR_p + EGFR_p	EGFR_p \|EGFR → EGFR_p + EGFR_p	V(24) = K(24,1) * [EGFR_p \|EGFR];
R25	PRKCA_p + VIM	PRKCA_p \|VIM	PRKCA_p + VIM → PRKCA_p \|VIM	V(25) = K(25,1) * [PRKCA_p] * [VIM] -K(25,2) * [PRKCA_p \|VIM];
R26	PRKCA_p \|VIM	PRKCA_p + VIM_p	PRKCA_p \|VIM → PRKCA_p + VIM_p	V(26) = K(26,1) * [PRKCA_p \|VIM];
R27	CDKN1B + MAPK1_p	MAPK1_p \|CDKN1B	CDKN1B + MAPK1_p → MAPK1_p \|CDKN1B	V(27) = K(27,1) * [MAPK1_p] * [CDKN1B] -K(27,2) * [MAPK1_p \|CDKN1B];
R28	MAPK1_p \|CDKN1B	CDKN1B_p + MAPK1_p	MAPK1_p \|CDKN1B → CDKN1B_p + MAPK1_p	V(28) = K(28,1) * [MAPK1_p \|CDKN1B];
R29	MAPK1_p + SMAD4	MAPK1_p \|SMAD4	MAPK1_p + SMAD4 → MAPK1_p \|SMAD4	V(29) = K(29,1) * [MAPK1_p] * [SMAD4] -K(29,2) * [MAPK1_p \|SMAD4];
R30	MAPK1_p \|SMAD4	MAPK1_p + SMAD4_p	MAPK1_p \|SMAD4 → MAPK1_p + SMAD4_p	V(30) = K(30,1) * [MAPK1_p \|SMAD4];
R31	ESR1 + MAPK1_p	MAPK1_p \|ESR1	ESR1 + MAPK1_p → MAPK1_p \|ESR1	V(31) = K(31,1) * [MAPK1_p] * [ESR1] -K(31,2) * [MAPK1_p \|ESR1];
R32	MAPK1_p \|ESR1	ESR1_p + MAPK1_p	MAPK1_p \|ESR1 → ESR1_p + MAPK1_p	V(32) = K(32,1) * [MAPK1_p \|ESR1];
R33	DNM1L + ROCK1	ROCK1 \|DNM1L	DNM1L + ROCK1 → ROCK1 \|DNM1L	V(33) = K(33,1) * [ROCK1] * [DNM1L] -K(33,2) * [ROCK1 \|DNM1L];
R34	ROCK1 \|DNM1L	DNM1L_p + ROCK1	ROCK1 \|DNM1L → DNM1L_p + ROCK1	V(34) = K(34,1) * [ROCK1 \|DNM1L];
R35	MAPK1_p + STK11	MAPK1_p \|STK11	MAPK1_p + STK11 → MAPK1_p \|STK11	V(35) = K(35,1) * [MAPK1_p] * [STK11] -K(35,2) * [MAPK1_p \|STK11];
R36	MAPK1_p \|STK11	MAPK1_p + STK11_p	MAPK1_p \|STK11 → MAPK1_p + STK11_p	V(36) = K(36,1) * [MAPK1_p \|STK11];
R37	JUN + MAPK1_p	MAPK1_p \|JUN	JUN + MAPK1_p → MAPK1_p \|JUN	V(37) = K(37,1) * [MAPK1_p] * [JUN] -K(37,2) * [MAPK1_p \|JUN];
R38	MAPK1_p \|JUN	JUN_p + MAPK1_p	MAPK1_p \|JUN → JUN_p + MAPK1_p	V(38) = K(38,1) * [MAPK1_p \|JUN];
R39	AKT1_p + NR4A1	AKT1_p \|NR4A1	AKT1_p + NR4A1 → AKT1_p \|NR4A1	V(39) = K(39,1) * [AKT1_p] * [NR4A1] -K(39,2) * [AKT1_p \|NR4A1];
R40	AKT1_p \|NR4A1	AKT1_p + NR4A1_p	AKT1_p \|NR4A1 → AKT1_p + NR4A1_p	V(40) = K(40,1) * [AKT1_p \|NR4A1];
R41	FOS + MAPK1_p	MAPK1_p \|FOS	FOS + MAPK1_p → MAPK1_p \|FOS	V(41) = K(41,1) * [MAPK1_p] * [FOS] -K(41,2) * [MAPK1_p \|FOS];
R42	MAPK1_p \|FOS	FOS_p + MAPK1_p	MAPK1_p \|FOS → FOS_p + MAPK1_p	V(42) = K(42,1) * [MAPK1_p \|FOS];
R43	EGFR + PRKCA_p	PRKCA_p \|EGFR	EGFR + PRKCA_p → PRKCA_p \|EGFR	V(43) = K(43,1) * [PRKCA_p] * [EGFR] -K(43,2) * [PRKCA_p \|EGFR];
R44	PRKCA_p \|EGFR	EGFR_p + PRKCA_p	PRKCA_p \|EGFR → EGFR_p + PRKCA_p	V(44) = K(44,1) * [PRKCA_p \|EGFR];
R45	STK11 + STK11_p	STK11_p \|STK11	STK11 + STK11_p → STK11_p \|STK11	V(45) = K(45,1) * [STK11_p] * [STK11] -K(45,2) * [STK11_p \|STK11];
R46	STK11_p \|STK11	STK11_p + STK11_p	STK11_p \|STK11 → STK11_p + STK11_p	V(46) = K(46,1) * [STK11_p \|STK11];
R47	AKT1_p + AR	AKT1_p \|AR	AKT1_p + AR → AKT1_p \|AR	V(47) = K(47,1) * [AKT1_p] * [AR] -K(47,2) * [AKT1_p \|AR];
R48	AKT1_p \|AR	AKT1_p + AR_p	AKT1_p \|AR → AKT1_p + AR_p	V(48) = K(48,1) * [AKT1_p \|AR];
R49	F3 + PRKCA_p	PRKCA_p \|F3	F3 + PRKCA_p → PRKCA_p \|F3	V(49) = K(49,1) * [PRKCA_p] * [F3] -K(49,2) * [PRKCA_p \|F3];
R50	PRKCA_p \|F3	F3_p + PRKCA_p	PRKCA_p \|F3 → F3_p + PRKCA_p	V(50) = K(50,1) * [PRKCA_p \|F3];
R51	MAPK1_p + RORA	MAPK1_p \|RORA	MAPK1_p + RORA → MAPK1_p \|RORA	V(51) = K(51,1) * [MAPK1_p] * [RORA] -K(51,2) * [MAPK1_p \|RORA];
R52	MAPK1_p \|RORA	MAPK1_p + RORA_p	MAPK1_p \|RORA → MAPK1_p + RORA_p	V(52) = K(52,1) * [MAPK1_p \|RORA];
R53	BCL2 + MAPK1_p	MAPK1_p \|BCL2	BCL2 + MAPK1_p → MAPK1_p \|BCL2	V(53) = K(53,1) * [MAPK1_p] * [BCL2] -K(53,2) * [MAPK1_p \|BCL2];
R54	MAPK1_p \|BCL2	BCL2_p + MAPK1_p	MAPK1_p \|BCL2 → BCL2_p + MAPK1_p	V(54) = K(54,1) * [MAPK1_p \|BCL2];
R55	INSR + INSR_p	INSR_p \|INSR	INSR + INSR_p → INSR_p \|INSR	V(55) = K(55,1) * [INSR_p] * [INSR] -K(55,2) * [INSR_p \|INSR];
R56	INSR_p \|INSR	INSR_p + INSR_p	INSR_p \|INSR → INSR_p + INSR_p	V(56) = K(56,1) * [INSR_p \|INSR];
R57	AKT1_p + BAD	AKT1_p \|BAD	AKT1_p + BAD → AKT1_p \|BAD	V(57) = K(57,1) * [AKT1_p] * [BAD] -K(57,2) * [AKT1_p \|BAD];
R58	AKT1_p \|BAD	AKT1_p + BAD_p	AKT1_p \|BAD → AKT1_p + BAD_p	V(58) = K(58,1) * [AKT1_p \|BAD];
R59	JAK1 + STAT1	JAK1 \|STAT1	JAK1 + STAT1 → JAK1 \|STAT1	V(59) = K(59,1) * [JAK1] * [STAT1] -K(59,2) * [JAK1 \|STAT1];
R60	JAK1 \|STAT1	JAK1 + STAT1_p	JAK1 \|STAT1 → JAK1 + STAT1_p	V(60) = K(60,1) * [JAK1 \|STAT1];
R61	DUSP1 + MAPK1_p	MAPK1_p \|DUSP1	DUSP1 + MAPK1_p → MAPK1_p \|DUSP1	V(61) = K(61,1) * [MAPK1_p] * [DUSP1] -K(61,2) * [MAPK1_p \|DUSP1];
R62	MAPK1_p \|DUSP1	DUSP1_p + MAPK1_p	MAPK1_p \|DUSP1 → DUSP1_p + MAPK1_p	V(62) = K(62,1) * [MAPK1_p \|DUSP1];
R63	AKT1_p + HSPB1	AKT1_p \|HSPB1	AKT1_p + HSPB1 → AKT1_p \|HSPB1	V(63) = K(63,1) * [AKT1_p] * [HSPB1] -K(63,2) * [AKT1_p \|HSPB1];
R64	AKT1_p \|HSPB1	AKT1_p + HSPB1_p	AKT1_p \|HSPB1 → AKT1_p + HSPB1_p	V(64) = K(64,1) * [AKT1_p \|HSPB1];
R65	HMGN1 + RPS6KA3_p	RPS6KA3_p \|HMGN1	HMGN1 + RPS6KA3_p → RPS6KA3_p \|HMGN1	V(65) = K(65,1) * [RPS6KA3_p] * [HMGN1] -K(65,2) * [RPS6KA3_p \|HMGN1];
R66	RPS6KA3_p \|HMGN1	HMGN1_p + RPS6KA3_p	RPS6KA3_p \|HMGN1 → HMGN1_p + RPS6KA3_p	V(66) = K(66,1) * [RPS6KA3_p \|HMGN1];
R67	PKN1 + PKN1_p	PKN1_p \|PKN1	PKN1 + PKN1_p → PKN1_p \|PKN1	V(67) = K(67,1) * [PKN1_p] * [PKN1] -K(67,2) * [PKN1_p \|PKN1];
R68	PKN1_p \|PKN1	PKN1_p + PKN1_p	PKN1_p \|PKN1 → PKN1_p + PKN1_p	V(68) = K(68,1) * [PKN1_p \|PKN1];
R69	AKT1_p + CDKN1A	AKT1_p \|CDKN1A	AKT1_p + CDKN1A → AKT1_p \|CDKN1A	V(69) = K(69,1) * [AKT1_p] * [CDKN1A] -K(69,2) * [AKT1_p \|CDKN1A];
R70	AKT1_p \|CDKN1A	AKT1_p + CDKN1A_p	AKT1_p \|CDKN1A → AKT1_p + CDKN1A_p	V(70) = K(70,1) * [AKT1_p \|CDKN1A];
R71	AQP1 + PRKCA_p	PRKCA_p \|AQP1	AQP1 + PRKCA_p → PRKCA_p \|AQP1	V(71) = K(71,1) * [PRKCA_p] * [AQP1] -K(71,2) * [PRKCA_p \|AQP1];
R72	PRKCA_p \|AQP1	AQP1_p + PRKCA_p	PRKCA_p \|AQP1 → AQP1_p + PRKCA_p	V(72) = K(72,1) * [PRKCA_p \|AQP1];
R73	AKT1_p + ESR1	AKT1_p \|ESR1	AKT1_p + ESR1 → AKT1_p \|ESR1	V(73) = K(73,1) * [AKT1_p] * [ESR1] -K(73,2) * [AKT1_p \|ESR1];
R74	AKT1_p \|ESR1	AKT1_p + ESR1_p	AKT1_p \|ESR1 → AKT1_p + ESR1_p	V(74) = K(74,1) * [AKT1_p \|ESR1];
R75	MAPK1_p + TSC2	MAPK1_p \|TSC2	MAPK1_p + TSC2 → MAPK1_p \|TSC2	V(75) = K(75,1) * [MAPK1_p] * [TSC2] -K(75,2) * [MAPK1_p \|TSC2];
R76	MAPK1_p \|TSC2	MAPK1_p + TSC2_p	MAPK1_p \|TSC2 → MAPK1_p + TSC2_p	V(76) = K(76,1) * [MAPK1_p \|TSC2];
R77	INSR_p + SIGNOR-C156	INSR_p \|SIGNOR-C156	INSR_p + SIGNOR-C156 → INSR_p \|SIGNOR-C156	V(77) = K(77,1) * [INSR_p] * [SIGNOR-C156] -K(77,2) * [INSR_p \|SIGNOR-C156];
R78	INSR_p \|SIGNOR-C156	INSR_p + SIGNOR-C156_p	INSR_p \|SIGNOR-C156 → INSR_p + SIGNOR-C156_p	V(78) = K(78,1) * [INSR_p \|SIGNOR-C156];
R79	MAPK1_p + RHOA	MAPK1_p \|RHOA	MAPK1_p + RHOA → MAPK1_p \|RHOA	V(79) = K(79,1) * [MAPK1_p] * [RHOA] -K(79,2) * [MAPK1_p \|RHOA];
R80	MAPK1_p \|RHOA	MAPK1_p + RHOA_p	MAPK1_p \|RHOA → MAPK1_p + RHOA_p	V(80) = K(80,1) * [MAPK1_p \|RHOA];
R81	CALM1 + EGFR_p	EGFR_p \|CALM1	CALM1 + EGFR_p → EGFR_p \|CALM1	V(81) = K(81,1) * [EGFR_p] * [CALM1] -K(81,2) * [EGFR_p \|CALM1];
R82	EGFR_p \|CALM1	CALM1_p + EGFR_p	EGFR_p \|CALM1 → CALM1_p + EGFR_p	V(82) = K(82,1) * [EGFR_p \|CALM1];
R83	PRKCA + PRKCA_p	PRKCA_p \|PRKCA	PRKCA + PRKCA_p → PRKCA_p \|PRKCA	V(83) = K(83,1) * [PRKCA_p] * [PRKCA] -K(83,2) * [PRKCA_p \|PRKCA];
R84	PRKCA_p \|PRKCA	PRKCA_p + PRKCA_p	PRKCA_p \|PRKCA → PRKCA_p + PRKCA_p	V(84) = K(84,1) * [PRKCA_p \|PRKCA];
R85	HMGN1 + PRKCA_p	PRKCA_p \|HMGN1	HMGN1 + PRKCA_p → PRKCA_p \|HMGN1	V(85) = K(85,1) * [PRKCA_p] * [HMGN1] -K(85,2) * [PRKCA_p \|HMGN1];
R86	PRKCA_p \|HMGN1	HMGN1_p + PRKCA_p	PRKCA_p \|HMGN1 → HMGN1_p + PRKCA_p	V(86) = K(86,1) * [PRKCA_p \|HMGN1];
R87	CALM1 + INSR_p	INSR_p \|CALM1	CALM1 + INSR_p → INSR_p \|CALM1	V(87) = K(87,1) * [INSR_p] * [CALM1] -K(87,2) * [INSR_p \|CALM1];
R88	INSR_p \|CALM1	CALM1_p + INSR_p	INSR_p \|CALM1 → CALM1_p + INSR_p	V(88) = K(88,1) * [INSR_p \|CALM1];
R89	CDKN1A + PRKCA_p	PRKCA_p \|CDKN1A	CDKN1A + PRKCA_p → PRKCA_p \|CDKN1A	V(89) = K(89,1) * [PRKCA_p] * [CDKN1A] -K(89,2) * [PRKCA_p \|CDKN1A];
R90	PRKCA_p \|CDKN1A	CDKN1A_p + PRKCA_p	PRKCA_p \|CDKN1A → CDKN1A_p + PRKCA_p	V(90) = K(90,1) * [PRKCA_p \|CDKN1A];
R91	ERN1 + ERN1_p	ERN1_p \|ERN1	ERN1 + ERN1_p → ERN1_p \|ERN1	V(91) = K(91,1) * [ERN1_p] * [ERN1] -K(91,2) * [ERN1_p \|ERN1];
R92	ERN1_p \|ERN1	ERN1_p + ERN1_p	ERN1_p \|ERN1 → ERN1_p + ERN1_p	V(92) = K(92,1) * [ERN1_p \|ERN1];
R93	DEPTOR + RPS6KA3_p	RPS6KA3_p \|DEPTOR	DEPTOR + RPS6KA3_p → RPS6KA3_p \|DEPTOR	V(93) = K(93,1) * [RPS6KA3_p] * [DEPTOR] -K(93,2) * [RPS6KA3_p \|DEPTOR];
R94	RPS6KA3_p \|DEPTOR	DEPTOR_p + RPS6KA3_p	RPS6KA3_p \|DEPTOR → DEPTOR_p + RPS6KA3_p	V(94) = K(94,1) * [RPS6KA3_p \|DEPTOR];
R95	AKT1_p + CDKN1B	AKT1_p \|CDKN1B	AKT1_p + CDKN1B → AKT1_p \|CDKN1B	V(95) = K(95,1) * [AKT1_p] * [CDKN1B] -K(95,2) * [AKT1_p \|CDKN1B];
R96	AKT1_p \|CDKN1B	AKT1_p + CDKN1B_p	AKT1_p \|CDKN1B → AKT1_p + CDKN1B_p	V(96) = K(96,1) * [AKT1_p \|CDKN1B];
R97	ATR + MDM2	ATR \|MDM2	ATR + MDM2 → ATR \|MDM2	V(97) = K(97,1) * [ATR] * [MDM2] -K(97,2) * [ATR \|MDM2];
R98	ATR \|MDM2	ATR + MDM2_p	ATR \|MDM2 → ATR + MDM2_p	V(98) = K(98,1) * [ATR \|MDM2];
R99	MAPK1_p + SIGNOR-C154	MAPK1_p \|SIGNOR-C154	MAPK1_p + SIGNOR-C154 → MAPK1_p \|SIGNOR-C154	V(99) = K(99,1) * [MAPK1_p] * [SIGNOR-C154] -K(99,2) * [MAPK1_p \|SIGNOR-C154];
R100	MAPK1_p \|SIGNOR-C154	MAPK1_p + SIGNOR-C154_p	MAPK1_p \|SIGNOR-C154 → MAPK1_p + SIGNOR-C154_p	V(100) = K(100,1) * [MAPK1_p \|SIGNOR-C154];
R101	BAD + RPS6KA3_p	RPS6KA3_p \|BAD	BAD + RPS6KA3_p → RPS6KA3_p \|BAD	V(101) = K(101,1) * [RPS6KA3_p] * [BAD] -K(101,2) * [RPS6KA3_p \|BAD];
R102	RPS6KA3_p \|BAD	BAD_p + RPS6KA3_p	RPS6KA3_p \|BAD → BAD_p + RPS6KA3_p	V(102) = K(102,1) * [RPS6KA3_p \|BAD];
R103	AKT1_p + RAC1	AKT1_p \|RAC1	AKT1_p + RAC1 → AKT1_p \|RAC1	V(103) = K(103,1) * [AKT1_p] * [RAC1] -K(103,2) * [AKT1_p \|RAC1];
R104	AKT1_p \|RAC1	AKT1_p + RAC1_p	AKT1_p \|RAC1 → AKT1_p + RAC1_p	V(104) = K(104,1) * [AKT1_p \|RAC1];
R105	PTEN + STK11_p	STK11_p \|PTEN	PTEN + STK11_p → STK11_p \|PTEN	V(105) = K(105,1) * [STK11_p] * [PTEN] -K(105,2) * [STK11_p \|PTEN];
R106	STK11_p \|PTEN	PTEN_p + STK11_p	STK11_p \|PTEN → PTEN_p + STK11_p	V(106) = K(106,1) * [STK11_p \|PTEN];
R107	HIPK2 + HIPK2_p	HIPK2_p \|HIPK2	HIPK2 + HIPK2_p → HIPK2_p \|HIPK2	V(107) = K(107,1) * [HIPK2_p] * [HIPK2] -K(107,2) * [HIPK2_p \|HIPK2];
R108	HIPK2_p \|HIPK2	HIPK2_p + HIPK2_p	HIPK2_p \|HIPK2 → HIPK2_p + HIPK2_p	V(108) = K(108,1) * [HIPK2_p \|HIPK2];
R109	CDKN1B + SGK1	SGK1 \|CDKN1B	CDKN1B + SGK1 → SGK1 \|CDKN1B	V(109) = K(109,1) * [SGK1] * [CDKN1B] -K(109,2) * [SGK1 \|CDKN1B];
R110	SGK1 \|CDKN1B	CDKN1B_p + SGK1	SGK1 \|CDKN1B → CDKN1B_p + SGK1	V(110) = K(110,1) * [SGK1 \|CDKN1B];
R111	CREB1 + RPS6KA3_p	RPS6KA3_p \|CREB1	CREB1 + RPS6KA3_p → RPS6KA3_p \|CREB1	V(111) = K(111,1) * [RPS6KA3_p] * [CREB1] -K(111,2) * [RPS6KA3_p \|CREB1];
R112	RPS6KA3_p \|CREB1	CREB1_p + RPS6KA3_p	RPS6KA3_p \|CREB1 → CREB1_p + RPS6KA3_p	V(112) = K(112,1) * [RPS6KA3_p \|CREB1];
R113	AKT1_p + TSC2	AKT1_p \|TSC2	AKT1_p + TSC2 → AKT1_p \|TSC2	V(113) = K(113,1) * [AKT1_p] * [TSC2] -K(113,2) * [AKT1_p \|TSC2];
R114	AKT1_p \|TSC2	AKT1_p + TSC2_p	AKT1_p \|TSC2 → AKT1_p + TSC2_p	V(114) = K(114,1) * [AKT1_p \|TSC2];
R115	PRKAA1 + PRKCA_p	PRKCA_p \|PRKAA1	PRKAA1 + PRKCA_p → PRKCA_p \|PRKAA1	V(115) = K(115,1) * [PRKCA_p] * [PRKAA1] -K(115,2) * [PRKCA_p \|PRKAA1];
R116	PRKCA_p \|PRKAA1	PRKAA1_p + PRKCA_p	PRKCA_p \|PRKAA1 → PRKAA1_p + PRKCA_p	V(116) = K(116,1) * [PRKCA_p \|PRKAA1];
R117	AKT1_p + EP300	AKT1_p \|EP300	AKT1_p + EP300 → AKT1_p \|EP300	V(117) = K(117,1) * [AKT1_p] * [EP300] -K(117,2) * [AKT1_p \|EP300];
R118	AKT1_p \|EP300	AKT1_p + EP300_p	AKT1_p \|EP300 → AKT1_p + EP300_p	V(118) = K(118,1) * [AKT1_p \|EP300];
R119	EGFR + MAPK1_p	MAPK1_p \|EGFR	EGFR + MAPK1_p → MAPK1_p \|EGFR	V(119) = K(119,1) * [MAPK1_p] * [EGFR] -K(119,2) * [MAPK1_p \|EGFR];
R120	MAPK1_p \|EGFR	EGFR_p + MAPK1_p	MAPK1_p \|EGFR → EGFR_p + MAPK1_p	V(120) = K(120,1) * [MAPK1_p \|EGFR];
R121	INSR + PRKCA_p	PRKCA_p \|INSR	INSR + PRKCA_p → PRKCA_p \|INSR	V(121) = K(121,1) * [PRKCA_p] * [INSR] -K(121,2) * [PRKCA_p \|INSR];
R122	PRKCA_p \|INSR	INSR_p + PRKCA_p	PRKCA_p \|INSR → INSR_p + PRKCA_p	V(122) = K(122,1) * [PRKCA_p \|INSR];
R123	BAD + SIGNOR-C156_p	SIGNOR-C156_p \|BAD	BAD + SIGNOR-C156_p → SIGNOR-C156_p \|BAD	V(123) = K(123,1) * [SIGNOR-C156_p] * [BAD] -K(123,2) * [SIGNOR-C156_p \|BAD];
R124	SIGNOR-C156_p \|BAD	BAD_p + SIGNOR-C156_p	SIGNOR-C156_p \|BAD → BAD_p + SIGNOR-C156_p	V(124) = K(124,1) * [SIGNOR-C156_p \|BAD];
R125	AKT1_p + VIM	AKT1_p \|VIM	AKT1_p + VIM → AKT1_p \|VIM	V(125) = K(125,1) * [AKT1_p] * [VIM] -K(125,2) * [AKT1_p \|VIM];
R126	AKT1_p \|VIM	AKT1_p + VIM_p	AKT1_p \|VIM → AKT1_p + VIM_p	V(126) = K(126,1) * [AKT1_p \|VIM];
R127	AXL + AXL_p	AXL_p \|AXL	AXL + AXL_p → AXL_p \|AXL	V(127) = K(127,1) * [AXL_p] * [AXL] -K(127,2) * [AXL_p \|AXL];
R128	AXL_p \|AXL	AXL_p + AXL_p	AXL_p \|AXL → AXL_p + AXL_p	V(128) = K(128,1) * [AXL_p \|AXL];
R129	DNMT1 + PRKAA1_p	PRKAA1_p \|DNMT1	DNMT1 + PRKAA1_p → PRKAA1_p \|DNMT1	V(129) = K(129,1) * [PRKAA1_p] * [DNMT1] -K(129,2) * [PRKAA1_p \|DNMT1];
R130	PRKAA1_p \|DNMT1	DNMT1_p + PRKAA1_p	PRKAA1_p \|DNMT1 → DNMT1_p + PRKAA1_p	V(130) = K(130,1) * [PRKAA1_p \|DNMT1];
R131	AKT1 + ILK_p	ILK_p \|AKT1	AKT1 + ILK_p → ILK_p \|AKT1	V(131) = K(131,1) * [ILK_p] * [AKT1] -K(131,2) * [ILK_p \|AKT1];
R132	ILK_p \|AKT1	AKT1_p + ILK_p	ILK_p \|AKT1 → AKT1_p + ILK_p	V(132) = K(132,1) * [ILK_p \|AKT1];
R133	MAPK1_p + SP1	MAPK1_p \|SP1	MAPK1_p + SP1 → MAPK1_p \|SP1	V(133) = K(133,1) * [MAPK1_p] * [SP1] -K(133,2) * [MAPK1_p \|SP1];
R134	MAPK1_p \|SP1	MAPK1_p + SP1_p	MAPK1_p \|SP1 → MAPK1_p + SP1_p	V(134) = K(134,1) * [MAPK1_p \|SP1];
R135	PTEN + ROCK1	ROCK1 \|PTEN	PTEN + ROCK1 → ROCK1 \|PTEN	V(135) = K(135,1) * [ROCK1] * [PTEN] -K(135,2) * [ROCK1 \|PTEN];
R136	ROCK1 \|PTEN	PTEN_p + ROCK1	ROCK1 \|PTEN → PTEN_p + ROCK1	V(136) = K(136,1) * [ROCK1 \|PTEN];
R137	BAD + MAPK1_p	MAPK1_p \|BAD	BAD + MAPK1_p → MAPK1_p \|BAD	V(137) = K(137,1) * [MAPK1_p] * [BAD] -K(137,2) * [MAPK1_p \|BAD];
R138	MAPK1_p \|BAD	BAD_p + MAPK1_p	MAPK1_p \|BAD → BAD_p + MAPK1_p	V(138) = K(138,1) * [MAPK1_p \|BAD];
R139	CDKN1A + MAPK1_p	MAPK1_p \|CDKN1A	CDKN1A + MAPK1_p → MAPK1_p \|CDKN1A	V(139) = K(139,1) * [MAPK1_p] * [CDKN1A] -K(139,2) * [MAPK1_p \|CDKN1A];
R140	MAPK1_p \|CDKN1A	CDKN1A_p + MAPK1_p	MAPK1_p \|CDKN1A → CDKN1A_p + MAPK1_p	V(140) = K(140,1) * [MAPK1_p \|CDKN1A];
R141	JAK1 + STAT3	JAK1 \|STAT3	JAK1 + STAT3 → JAK1 \|STAT3	V(141) = K(141,1) * [JAK1] * [STAT3] -K(141,2) * [JAK1 \|STAT3];
R142	JAK1 \|STAT3	JAK1 + STAT3_p	JAK1 \|STAT3 → JAK1 + STAT3_p	V(142) = K(142,1) * [JAK1 \|STAT3];
R143	AKT1_p + NR3C1	AKT1_p \|NR3C1	AKT1_p + NR3C1 → AKT1_p \|NR3C1	V(143) = K(143,1) * [AKT1_p] * [NR3C1] -K(143,2) * [AKT1_p \|NR3C1];
R144	AKT1_p \|NR3C1	AKT1_p + NR3C1_p	AKT1_p \|NR3C1 → AKT1_p + NR3C1_p	V(144) = K(144,1) * [AKT1_p \|NR3C1];
R145	HES1 + PRKCA_p	PRKCA_p \|HES1	HES1 + PRKCA_p → PRKCA_p \|HES1	V(145) = K(145,1) * [PRKCA_p] * [HES1] -K(145,2) * [PRKCA_p \|HES1];
R146	PRKCA_p \|HES1	HES1_p + PRKCA_p	PRKCA_p \|HES1 → HES1_p + PRKCA_p	V(146) = K(146,1) * [PRKCA_p \|HES1];
R147	EGFR_p + SIGNOR-C120	EGFR_p \|SIGNOR-C120	EGFR_p + SIGNOR-C120 → EGFR_p \|SIGNOR-C120	V(147) = K(147,1) * [EGFR_p] * [SIGNOR-C120] -K(147,2) * [EGFR_p \|SIGNOR-C120];
R148	EGFR_p \|SIGNOR-C120	EGFR_p + SIGNOR-C120_p	EGFR_p \|SIGNOR-C120 → EGFR_p + SIGNOR-C120_p	V(148) = K(148,1) * [EGFR_p \|SIGNOR-C120];
R149	SMAD4 + STK11_p	STK11_p \|SMAD4	SMAD4 + STK11_p → STK11_p \|SMAD4	V(149) = K(149,1) * [STK11_p] * [SMAD4] -K(149,2) * [STK11_p \|SMAD4];
R150	STK11_p \|SMAD4	SMAD4_p + STK11_p	STK11_p \|SMAD4 → SMAD4_p + STK11_p	V(150) = K(150,1) * [STK11_p \|SMAD4];
R151	ANXA1 + PRKCA_p	PRKCA_p \|ANXA1	ANXA1 + PRKCA_p → PRKCA_p \|ANXA1	V(151) = K(151,1) * [PRKCA_p] * [ANXA1] -K(151,2) * [PRKCA_p \|ANXA1];
R152	PRKCA_p \|ANXA1	ANXA1_p + PRKCA_p	PRKCA_p \|ANXA1 → ANXA1_p + PRKCA_p	V(152) = K(152,1) * [PRKCA_p \|ANXA1];
R153	AXL_p + EGFR	AXL_p \|EGFR	AXL_p + EGFR → AXL_p \|EGFR	V(153) = K(153,1) * [AXL_p] * [EGFR] -K(153,2) * [AXL_p \|EGFR];
R154	AXL_p \|EGFR	AXL_p + EGFR_p	AXL_p \|EGFR → AXL_p + EGFR_p	V(154) = K(154,1) * [AXL_p \|EGFR];
R155	JAK1 + STAT6	JAK1 \|STAT6	JAK1 + STAT6 → JAK1 \|STAT6	V(155) = K(155,1) * [JAK1] * [STAT6] -K(155,2) * [JAK1 \|STAT6];
R156	JAK1 \|STAT6	JAK1 + STAT6_p	JAK1 \|STAT6 → JAK1 + STAT6_p	V(156) = K(156,1) * [JAK1 \|STAT6];
R157	SGK1 + TSC2	SGK1 \|TSC2	SGK1 + TSC2 → SGK1 \|TSC2	V(157) = K(157,1) * [SGK1] * [TSC2] -K(157,2) * [SGK1 \|TSC2];
R158	SGK1 \|TSC2	SGK1 + TSC2_p	SGK1 \|TSC2 → SGK1 + TSC2_p	V(158) = K(158,1) * [SGK1 \|TSC2];
R159	AKT1_p + YAP1	AKT1_p \|YAP1	AKT1_p + YAP1 → AKT1_p \|YAP1	V(159) = K(159,1) * [AKT1_p] * [YAP1] -K(159,2) * [AKT1_p \|YAP1];
R160	AKT1_p \|YAP1	AKT1_p + YAP1_p	AKT1_p \|YAP1 → AKT1_p + YAP1_p	V(160) = K(160,1) * [AKT1_p \|YAP1];
R161	AKT1 + SIGNOR-C156_p	SIGNOR-C156_p \|AKT1	AKT1 + SIGNOR-C156_p → SIGNOR-C156_p \|AKT1	V(161) = K(161,1) * [SIGNOR-C156_p] * [AKT1] -K(161,2) * [SIGNOR-C156_p \|AKT1];
R162	SIGNOR-C156_p \|AKT1	AKT1_p + SIGNOR-C156_p	SIGNOR-C156_p \|AKT1 → AKT1_p + SIGNOR-C156_p	V(162) = K(162,1) * [SIGNOR-C156_p \|AKT1];
R163	FOS + RPS6KA3_p	RPS6KA3_p \|FOS	FOS + RPS6KA3_p → RPS6KA3_p \|FOS	V(163) = K(163,1) * [RPS6KA3_p] * [FOS] -K(163,2) * [RPS6KA3_p \|FOS];
R164	RPS6KA3_p \|FOS	FOS_p + RPS6KA3_p	RPS6KA3_p \|FOS → FOS_p + RPS6KA3_p	V(164) = K(164,1) * [RPS6KA3_p \|FOS];
R165	AKT1_p + RPS6KA3	AKT1_p \|RPS6KA3	AKT1_p + RPS6KA3 → AKT1_p \|RPS6KA3	V(165) = K(165,1) * [AKT1_p] * [RPS6KA3] -K(165,2) * [AKT1_p \|RPS6KA3];
R166	AKT1_p \|RPS6KA3	AKT1_p + RPS6KA3_p	AKT1_p \|RPS6KA3 → AKT1_p + RPS6KA3_p	V(166) = K(166,1) * [AKT1_p \|RPS6KA3];
R167	AKT1_p + DNMT1	AKT1_p \|DNMT1	AKT1_p + DNMT1 → AKT1_p \|DNMT1	V(167) = K(167,1) * [AKT1_p] * [DNMT1] -K(167,2) * [AKT1_p \|DNMT1];
R168	AKT1_p \|DNMT1	AKT1_p + DNMT1_p	AKT1_p \|DNMT1 → AKT1_p + DNMT1_p	V(168) = K(168,1) * [AKT1_p \|DNMT1];
R169	RPS6KA3 + RPS6KA3_p	RPS6KA3_p \|RPS6KA3	RPS6KA3 + RPS6KA3_p → RPS6KA3_p \|RPS6KA3	V(169) = K(169,1) * [RPS6KA3_p] * [RPS6KA3] -K(169,2) * [RPS6KA3_p \|RPS6KA3];
R170	RPS6KA3_p \|RPS6KA3	RPS6KA3_p + RPS6KA3_p	RPS6KA3_p \|RPS6KA3 → RPS6KA3_p + RPS6KA3_p	V(170) = K(170,1) * [RPS6KA3_p \|RPS6KA3];
R171	EP300 + PRKAA1_p	PRKAA1_p \|EP300	EP300 + PRKAA1_p → PRKAA1_p \|EP300	V(171) = K(171,1) * [PRKAA1_p] * [EP300] -K(171,2) * [PRKAA1_p \|EP300];
R172	PRKAA1_p \|EP300	EP300_p + PRKAA1_p	PRKAA1_p \|EP300 → EP300_p + PRKAA1_p	V(172) = K(172,1) * [PRKAA1_p \|EP300];
R173	HIPK2_p + MECP2	HIPK2_p \|MECP2	HIPK2_p + MECP2 → HIPK2_p \|MECP2	V(173) = K(173,1) * [HIPK2_p] * [MECP2] -K(173,2) * [HIPK2_p \|MECP2];
R174	HIPK2_p \|MECP2	HIPK2_p + MECP2_p	HIPK2_p \|MECP2 → HIPK2_p + MECP2_p	V(174) = K(174,1) * [HIPK2_p \|MECP2];
R175	AKT1_p + CTNNB1	AKT1_p \|CTNNB1	AKT1_p + CTNNB1 → AKT1_p \|CTNNB1	V(175) = K(175,1) * [AKT1_p] * [CTNNB1] -K(175,2) * [AKT1_p \|CTNNB1];
R176	AKT1_p \|CTNNB1	AKT1_p + CTNNB1_p	AKT1_p \|CTNNB1 → AKT1_p + CTNNB1_p	V(176) = K(176,1) * [AKT1_p \|CTNNB1];
R177	CYBA + PRKCA_p	PRKCA_p \|CYBA	CYBA + PRKCA_p → PRKCA_p \|CYBA	V(177) = K(177,1) * [PRKCA_p] * [CYBA] -K(177,2) * [PRKCA_p \|CYBA];
R178	PRKCA_p \|CYBA	CYBA_p + PRKCA_p	PRKCA_p \|CYBA → CYBA_p + PRKCA_p	V(178) = K(178,1) * [PRKCA_p \|CYBA];
R179	ESR1 + RPS6KA3_p	RPS6KA3_p \|ESR1	ESR1 + RPS6KA3_p → RPS6KA3_p \|ESR1	V(179) = K(179,1) * [RPS6KA3_p] * [ESR1] -K(179,2) * [RPS6KA3_p \|ESR1];
R180	RPS6KA3_p \|ESR1	ESR1_p + RPS6KA3_p	RPS6KA3_p \|ESR1 → ESR1_p + RPS6KA3_p	V(180) = K(180,1) * [RPS6KA3_p \|ESR1];
R181	NR4A1 + RPS6KA3_p	RPS6KA3_p \|NR4A1	NR4A1 + RPS6KA3_p → RPS6KA3_p \|NR4A1	V(181) = K(181,1) * [RPS6KA3_p] * [NR4A1] -K(181,2) * [RPS6KA3_p \|NR4A1];
R182	RPS6KA3_p \|NR4A1	NR4A1_p + RPS6KA3_p	RPS6KA3_p \|NR4A1 → NR4A1_p + RPS6KA3_p	V(182) = K(182,1) * [RPS6KA3_p \|NR4A1];
R183	BAD + PRKCA_p	PRKCA_p \|BAD	BAD + PRKCA_p → PRKCA_p \|BAD	V(183) = K(183,1) * [PRKCA_p] * [BAD] -K(183,2) * [PRKCA_p \|BAD];
R184	PRKCA_p \|BAD	BAD_p + PRKCA_p	PRKCA_p \|BAD → BAD_p + PRKCA_p	V(184) = K(184,1) * [PRKCA_p \|BAD];
R185	STK11_p + YAP1	STK11_p \|YAP1	STK11_p + YAP1 → STK11_p \|YAP1	V(185) = K(185,1) * [STK11_p] * [YAP1] -K(185,2) * [STK11_p \|YAP1];
R186	STK11_p \|YAP1	STK11_p + YAP1_p	STK11_p \|YAP1 → STK11_p + YAP1_p	V(186) = K(186,1) * [STK11_p \|YAP1];
R187	MAPK1 + MAPK1_p	MAPK1_p \|MAPK1	MAPK1 + MAPK1_p → MAPK1_p \|MAPK1	V(187) = K(187,1) * [MAPK1_p] * [MAPK1] -K(187,2) * [MAPK1_p \|MAPK1];
R188	MAPK1_p \|MAPK1	MAPK1_p + MAPK1_p	MAPK1_p \|MAPK1 → MAPK1_p + MAPK1_p	V(188) = K(188,1) * [MAPK1_p \|MAPK1];
R189	PRKAA1_p + TSC2	PRKAA1_p \|TSC2	PRKAA1_p + TSC2 → PRKAA1_p \|TSC2	V(189) = K(189,1) * [PRKAA1_p] * [TSC2] -K(189,2) * [PRKAA1_p \|TSC2];
R190	PRKAA1_p \|TSC2	PRKAA1_p + TSC2_p	PRKAA1_p \|TSC2 → PRKAA1_p + TSC2_p	V(190) = K(190,1) * [PRKAA1_p \|TSC2];
R191	MAPK1_p + ZFP36	MAPK1_p \|ZFP36	MAPK1_p + ZFP36 → MAPK1_p \|ZFP36	V(191) = K(191,1) * [MAPK1_p] * [ZFP36] -K(191,2) * [MAPK1_p \|ZFP36];
R192	MAPK1_p \|ZFP36	MAPK1_p + ZFP36_p	MAPK1_p \|ZFP36 → MAPK1_p + ZFP36_p	V(192) = K(192,1) * [MAPK1_p \|ZFP36];
R193	MAPK1_p + RCAN1	MAPK1_p \|RCAN1	MAPK1_p + RCAN1 → MAPK1_p \|RCAN1	V(193) = K(193,1) * [MAPK1_p] * [RCAN1] -K(193,2) * [MAPK1_p \|RCAN1];
R194	MAPK1_p \|RCAN1	MAPK1_p + RCAN1_p	MAPK1_p \|RCAN1 → MAPK1_p + RCAN1_p	V(194) = K(194,1) * [MAPK1_p \|RCAN1];
R195	EGFR + PKN1_p	PKN1_p \|EGFR	EGFR + PKN1_p → PKN1_p \|EGFR	V(195) = K(195,1) * [PKN1_p] * [EGFR] -K(195,2) * [PKN1_p \|EGFR];
R196	PKN1_p \|EGFR	EGFR_p + PKN1_p	PKN1_p \|EGFR → EGFR_p + PKN1_p	V(196) = K(196,1) * [PKN1_p \|EGFR];
R197	AEBP1 + MAPK1_p	MAPK1_p \|AEBP1	AEBP1 + MAPK1_p → MAPK1_p \|AEBP1	V(197) = K(197,1) * [MAPK1_p] * [AEBP1] -K(197,2) * [MAPK1_p \|AEBP1];
R198	MAPK1_p \|AEBP1	AEBP1_p + MAPK1_p	MAPK1_p \|AEBP1 → AEBP1_p + MAPK1_p	V(198) = K(198,1) * [MAPK1_p \|AEBP1];
R199	EGFR_p + ESR1	EGFR_p \|ESR1	EGFR_p + ESR1 → EGFR_p \|ESR1	V(199) = K(199,1) * [EGFR_p] * [ESR1] -K(199,2) * [EGFR_p \|ESR1];

Reaction ID	Reactants	Products	Original Text	ODE Equations
R1	JUN_p + SMAD4_p	SIGNOR-C10	JUN_p + SMAD4_p → SIGNOR-C10	V(1) = K(1,1) * [SMAD4_p] * [JUN_p] -K(1,2) * [SIGNOR-C10];
R2	SP1_p + STAT3_p	SIGNOR-C74	SP1_p + STAT3_p → SIGNOR-C74	V(2) = K(2,1) * [STAT3_p] * [SP1_p] -K(2,2) * [SIGNOR-C74];
R3	STAT1_p + STAT3_p	SIGNOR-C118	STAT1_p + STAT3_p → SIGNOR-C118	V(3) = K(3,1) * [STAT1_p] * [STAT3_p] -K(3,2) * [SIGNOR-C118];
R4	JAK1 + SIGNOR-C118	SIGNOR-C120	JAK1 + SIGNOR-C118 → SIGNOR-C120	V(4) = K(4,1) * [SIGNOR-C118] * [JAK1] -K(4,2) * [SIGNOR-C120];
R5	FOS_p + FOS_p + FOS_p + FOS_p + JUN_p + JUN_p + JUN_p + JUN_p	SIGNOR-C154	FOS_p + FOS_p + FOS_p + FOS_p + JUN_p + JUN_p + JUN_p + JUN_p → SIGNOR-C154	V(5) = K(5,1) * [FOS_p] * [JUN_p] * [JUN_p] * [FOS_p] * [JUN_p] * [FOS_p] * [FOS_p] * [JUN_p] -K(5,2) * [SIGNOR-C154];
R6	PIK3CA + PIK3R1_p	SIGNOR-C156	PIK3CA + PIK3R1_p → SIGNOR-C156	V(6) = K(6,1) * [PIK3R1_p] * [PIK3CA] -K(6,2) * [SIGNOR-C156];
R7	EP300 + MAPK1_p	MAPK1_p \|EP300	EP300 + MAPK1_p → MAPK1_p \|EP300	V(7) = K(7,1) * [MAPK1_p] * [EP300] -K(7,2) * [MAPK1_p \|EP300];
R8	MAPK1_p \|EP300	EP300_p + MAPK1_p	MAPK1_p \|EP300 → EP300_p + MAPK1_p	V(8) = K(8,1) * [MAPK1_p \|EP300];
R9	HIF1A + MAPK1_p	MAPK1_p \|HIF1A	HIF1A + MAPK1_p → MAPK1_p \|HIF1A	V(9) = K(9,1) * [MAPK1_p] * [HIF1A] -K(9,2) * [MAPK1_p \|HIF1A];
R10	MAPK1_p \|HIF1A	HIF1A_p + MAPK1_p	MAPK1_p \|HIF1A → HIF1A_p + MAPK1_p	V(10) = K(10,1) * [MAPK1_p \|HIF1A];
R11	MAPK1_p + NR3C1	MAPK1_p \|NR3C1	MAPK1_p + NR3C1 → MAPK1_p \|NR3C1	V(11) = K(11,1) * [MAPK1_p] * [NR3C1] -K(11,2) * [MAPK1_p \|NR3C1];
R12	MAPK1_p \|NR3C1	MAPK1_p + NR3C1_p	MAPK1_p \|NR3C1 → MAPK1_p + NR3C1_p	V(12) = K(12,1) * [MAPK1_p \|NR3C1];
R13	MAPK1_p + RPS6KA3	MAPK1_p \|RPS6KA3	MAPK1_p + RPS6KA3 → MAPK1_p \|RPS6KA3	V(13) = K(13,1) * [MAPK1_p] * [RPS6KA3] -K(13,2) * [MAPK1_p \|RPS6KA3];
R14	MAPK1_p \|RPS6KA3	MAPK1_p + RPS6KA3_p	MAPK1_p \|RPS6KA3 → MAPK1_p + RPS6KA3_p	V(14) = K(14,1) * [MAPK1_p \|RPS6KA3];
R15	MAPK1_p + PRDX6	MAPK1_p \|PRDX6	MAPK1_p + PRDX6 → MAPK1_p \|PRDX6	V(15) = K(15,1) * [MAPK1_p] * [PRDX6] -K(15,2) * [MAPK1_p \|PRDX6];
R16	MAPK1_p \|PRDX6	MAPK1_p + PRDX6_p	MAPK1_p \|PRDX6 → MAPK1_p + PRDX6_p	V(16) = K(16,1) * [MAPK1_p \|PRDX6];
R17	CTNNB1 + PRKCA_p	PRKCA_p \|CTNNB1	CTNNB1 + PRKCA_p → PRKCA_p \|CTNNB1	V(17) = K(17,1) * [PRKCA_p] * [CTNNB1] -K(17,2) * [PRKCA_p \|CTNNB1];
R18	PRKCA_p \|CTNNB1	CTNNB1_p + PRKCA_p	PRKCA_p \|CTNNB1 → CTNNB1_p + PRKCA_p	V(18) = K(18,1) * [PRKCA_p \|CTNNB1];
R19	AKT1_p + MDM2	AKT1_p \|MDM2	AKT1_p + MDM2 → AKT1_p \|MDM2	V(19) = K(19,1) * [AKT1_p] * [MDM2] -K(19,2) * [AKT1_p \|MDM2];
R20	AKT1_p \|MDM2	AKT1_p + MDM2_p	AKT1_p \|MDM2 → AKT1_p + MDM2_p	V(20) = K(20,1) * [AKT1_p \|MDM2];
R21	AKT1_p + PRKAA1	AKT1_p \|PRKAA1	AKT1_p + PRKAA1 → AKT1_p \|PRKAA1	V(21) = K(21,1) * [AKT1_p] * [PRKAA1] -K(21,2) * [AKT1_p \|PRKAA1];
R22	AKT1_p \|PRKAA1	AKT1_p + PRKAA1_p	AKT1_p \|PRKAA1 → AKT1_p + PRKAA1_p	V(22) = K(22,1) * [AKT1_p \|PRKAA1];
R23	EGFR + EGFR_p	EGFR_p \|EGFR	EGFR + EGFR_p → EGFR_p \|EGFR	V(23) = K(23,1) * [EGFR_p] * [EGFR] -K(23,2) * [EGFR_p \|EGFR];
R24	EGFR_p \|EGFR	EGFR_p + EGFR_p	EGFR_p \|EGFR → EGFR_p + EGFR_p	V(24) = K(24,1) * [EGFR_p \|EGFR];
R25	PRKCA_p + VIM	PRKCA_p \|VIM	PRKCA_p + VIM → PRKCA_p \|VIM	V(25) = K(25,1) * [PRKCA_p] * [VIM] -K(25,2) * [PRKCA_p \|VIM];
R26	PRKCA_p \|VIM	PRKCA_p + VIM_p	PRKCA_p \|VIM → PRKCA_p + VIM_p	V(26) = K(26,1) * [PRKCA_p \|VIM];
R27	CDKN1B + MAPK1_p	MAPK1_p \|CDKN1B	CDKN1B + MAPK1_p → MAPK1_p \|CDKN1B	V(27) = K(27,1) * [MAPK1_p] * [CDKN1B] -K(27,2) * [MAPK1_p \|CDKN1B];
R28	MAPK1_p \|CDKN1B	CDKN1B_p + MAPK1_p	MAPK1_p \|CDKN1B → CDKN1B_p + MAPK1_p	V(28) = K(28,1) * [MAPK1_p \|CDKN1B];
R29	MAPK1_p + SMAD4	MAPK1_p \|SMAD4	MAPK1_p + SMAD4 → MAPK1_p \|SMAD4	V(29) = K(29,1) * [MAPK1_p] * [SMAD4] -K(29,2) * [MAPK1_p \|SMAD4];
R30	MAPK1_p \|SMAD4	MAPK1_p + SMAD4_p	MAPK1_p \|SMAD4 → MAPK1_p + SMAD4_p	V(30) = K(30,1) * [MAPK1_p \|SMAD4];
R31	ESR1 + MAPK1_p	MAPK1_p \|ESR1	ESR1 + MAPK1_p → MAPK1_p \|ESR1	V(31) = K(31,1) * [MAPK1_p] * [ESR1] -K(31,2) * [MAPK1_p \|ESR1];
R32	MAPK1_p \|ESR1	ESR1_p + MAPK1_p	MAPK1_p \|ESR1 → ESR1_p + MAPK1_p	V(32) = K(32,1) * [MAPK1_p \|ESR1];
R33	DNM1L + ROCK1	ROCK1 \|DNM1L	DNM1L + ROCK1 → ROCK1 \|DNM1L	V(33) = K(33,1) * [ROCK1] * [DNM1L] -K(33,2) * [ROCK1 \|DNM1L];
R34	ROCK1 \|DNM1L	DNM1L_p + ROCK1	ROCK1 \|DNM1L → DNM1L_p + ROCK1	V(34) = K(34,1) * [ROCK1 \|DNM1L];
R35	MAPK1_p + STK11	MAPK1_p \|STK11	MAPK1_p + STK11 → MAPK1_p \|STK11	V(35) = K(35,1) * [MAPK1_p] * [STK11] -K(35,2) * [MAPK1_p \|STK11];
R36	MAPK1_p \|STK11	MAPK1_p + STK11_p	MAPK1_p \|STK11 → MAPK1_p + STK11_p	V(36) = K(36,1) * [MAPK1_p \|STK11];
R37	JUN + MAPK1_p	MAPK1_p \|JUN	JUN + MAPK1_p → MAPK1_p \|JUN	V(37) = K(37,1) * [MAPK1_p] * [JUN] -K(37,2) * [MAPK1_p \|JUN];
R38	MAPK1_p \|JUN	JUN_p + MAPK1_p	MAPK1_p \|JUN → JUN_p + MAPK1_p	V(38) = K(38,1) * [MAPK1_p \|JUN];
R39	AKT1_p + NR4A1	AKT1_p \|NR4A1	AKT1_p + NR4A1 → AKT1_p \|NR4A1	V(39) = K(39,1) * [AKT1_p] * [NR4A1] -K(39,2) * [AKT1_p \|NR4A1];
R40	AKT1_p \|NR4A1	AKT1_p + NR4A1_p	AKT1_p \|NR4A1 → AKT1_p + NR4A1_p	V(40) = K(40,1) * [AKT1_p \|NR4A1];
R41	FOS + MAPK1_p	MAPK1_p \|FOS	FOS + MAPK1_p → MAPK1_p \|FOS	V(41) = K(41,1) * [MAPK1_p] * [FOS] -K(41,2) * [MAPK1_p \|FOS];
R42	MAPK1_p \|FOS	FOS_p + MAPK1_p	MAPK1_p \|FOS → FOS_p + MAPK1_p	V(42) = K(42,1) * [MAPK1_p \|FOS];
R43	EGFR + PRKCA_p	PRKCA_p \|EGFR	EGFR + PRKCA_p → PRKCA_p \|EGFR	V(43) = K(43,1) * [PRKCA_p] * [EGFR] -K(43,2) * [PRKCA_p \|EGFR];
R44	PRKCA_p \|EGFR	EGFR_p + PRKCA_p	PRKCA_p \|EGFR → EGFR_p + PRKCA_p	V(44) = K(44,1) * [PRKCA_p \|EGFR];
R45	STK11 + STK11_p	STK11_p \|STK11	STK11 + STK11_p → STK11_p \|STK11	V(45) = K(45,1) * [STK11_p] * [STK11] -K(45,2) * [STK11_p \|STK11];
R46	STK11_p \|STK11	STK11_p + STK11_p	STK11_p \|STK11 → STK11_p + STK11_p	V(46) = K(46,1) * [STK11_p \|STK11];
R47	AKT1_p + AR	AKT1_p \|AR	AKT1_p + AR → AKT1_p \|AR	V(47) = K(47,1) * [AKT1_p] * [AR] -K(47,2) * [AKT1_p \|AR];
R48	AKT1_p \|AR	AKT1_p + AR_p	AKT1_p \|AR → AKT1_p + AR_p	V(48) = K(48,1) * [AKT1_p \|AR];
R49	F3 + PRKCA_p	PRKCA_p \|F3	F3 + PRKCA_p → PRKCA_p \|F3	V(49) = K(49,1) * [PRKCA_p] * [F3] -K(49,2) * [PRKCA_p \|F3];
R50	PRKCA_p \|F3	F3_p + PRKCA_p	PRKCA_p \|F3 → F3_p + PRKCA_p	V(50) = K(50,1) * [PRKCA_p \|F3];
R51	MAPK1_p + RORA	MAPK1_p \|RORA	MAPK1_p + RORA → MAPK1_p \|RORA	V(51) = K(51,1) * [MAPK1_p] * [RORA] -K(51,2) * [MAPK1_p \|RORA];
R52	MAPK1_p \|RORA	MAPK1_p + RORA_p	MAPK1_p \|RORA → MAPK1_p + RORA_p	V(52) = K(52,1) * [MAPK1_p \|RORA];
R53	BCL2 + MAPK1_p	MAPK1_p \|BCL2	BCL2 + MAPK1_p → MAPK1_p \|BCL2	V(53) = K(53,1) * [MAPK1_p] * [BCL2] -K(53,2) * [MAPK1_p \|BCL2];
R54	MAPK1_p \|BCL2	BCL2_p + MAPK1_p	MAPK1_p \|BCL2 → BCL2_p + MAPK1_p	V(54) = K(54,1) * [MAPK1_p \|BCL2];
R55	INSR + INSR_p	INSR_p \|INSR	INSR + INSR_p → INSR_p \|INSR	V(55) = K(55,1) * [INSR_p] * [INSR] -K(55,2) * [INSR_p \|INSR];
R56	INSR_p \|INSR	INSR_p + INSR_p	INSR_p \|INSR → INSR_p + INSR_p	V(56) = K(56,1) * [INSR_p \|INSR];
R57	AKT1_p + BAD	AKT1_p \|BAD	AKT1_p + BAD → AKT1_p \|BAD	V(57) = K(57,1) * [AKT1_p] * [BAD] -K(57,2) * [AKT1_p \|BAD];
R58	AKT1_p \|BAD	AKT1_p + BAD_p	AKT1_p \|BAD → AKT1_p + BAD_p	V(58) = K(58,1) * [AKT1_p \|BAD];
R59	JAK1 + STAT1	JAK1 \|STAT1	JAK1 + STAT1 → JAK1 \|STAT1	V(59) = K(59,1) * [JAK1] * [STAT1] -K(59,2) * [JAK1 \|STAT1];
R60	JAK1 \|STAT1	JAK1 + STAT1_p	JAK1 \|STAT1 → JAK1 + STAT1_p	V(60) = K(60,1) * [JAK1 \|STAT1];
R61	DUSP1 + MAPK1_p	MAPK1_p \|DUSP1	DUSP1 + MAPK1_p → MAPK1_p \|DUSP1	V(61) = K(61,1) * [MAPK1_p] * [DUSP1] -K(61,2) * [MAPK1_p \|DUSP1];
R62	MAPK1_p \|DUSP1	DUSP1_p + MAPK1_p	MAPK1_p \|DUSP1 → DUSP1_p + MAPK1_p	V(62) = K(62,1) * [MAPK1_p \|DUSP1];
R63	AKT1_p + HSPB1	AKT1_p \|HSPB1	AKT1_p + HSPB1 → AKT1_p \|HSPB1	V(63) = K(63,1) * [AKT1_p] * [HSPB1] -K(63,2) * [AKT1_p \|HSPB1];
R64	AKT1_p \|HSPB1	AKT1_p + HSPB1_p	AKT1_p \|HSPB1 → AKT1_p + HSPB1_p	V(64) = K(64,1) * [AKT1_p \|HSPB1];
R65	HMGN1 + RPS6KA3_p	RPS6KA3_p \|HMGN1	HMGN1 + RPS6KA3_p → RPS6KA3_p \|HMGN1	V(65) = K(65,1) * [RPS6KA3_p] * [HMGN1] -K(65,2) * [RPS6KA3_p \|HMGN1];
R66	RPS6KA3_p \|HMGN1	HMGN1_p + RPS6KA3_p	RPS6KA3_p \|HMGN1 → HMGN1_p + RPS6KA3_p	V(66) = K(66,1) * [RPS6KA3_p \|HMGN1];
R67	PKN1 + PKN1_p	PKN1_p \|PKN1	PKN1 + PKN1_p → PKN1_p \|PKN1	V(67) = K(67,1) * [PKN1_p] * [PKN1] -K(67,2) * [PKN1_p \|PKN1];
R68	PKN1_p \|PKN1	PKN1_p + PKN1_p	PKN1_p \|PKN1 → PKN1_p + PKN1_p	V(68) = K(68,1) * [PKN1_p \|PKN1];
R69	AKT1_p + CDKN1A	AKT1_p \|CDKN1A	AKT1_p + CDKN1A → AKT1_p \|CDKN1A	V(69) = K(69,1) * [AKT1_p] * [CDKN1A] -K(69,2) * [AKT1_p \|CDKN1A];
R70	AKT1_p \|CDKN1A	AKT1_p + CDKN1A_p	AKT1_p \|CDKN1A → AKT1_p + CDKN1A_p	V(70) = K(70,1) * [AKT1_p \|CDKN1A];
R71	AQP1 + PRKCA_p	PRKCA_p \|AQP1	AQP1 + PRKCA_p → PRKCA_p \|AQP1	V(71) = K(71,1) * [PRKCA_p] * [AQP1] -K(71,2) * [PRKCA_p \|AQP1];
R72	PRKCA_p \|AQP1	AQP1_p + PRKCA_p	PRKCA_p \|AQP1 → AQP1_p + PRKCA_p	V(72) = K(72,1) * [PRKCA_p \|AQP1];
R73	AKT1_p + ESR1	AKT1_p \|ESR1	AKT1_p + ESR1 → AKT1_p \|ESR1	V(73) = K(73,1) * [AKT1_p] * [ESR1] -K(73,2) * [AKT1_p \|ESR1];
R74	AKT1_p \|ESR1	AKT1_p + ESR1_p	AKT1_p \|ESR1 → AKT1_p + ESR1_p	V(74) = K(74,1) * [AKT1_p \|ESR1];
R75	MAPK1_p + TSC2	MAPK1_p \|TSC2	MAPK1_p + TSC2 → MAPK1_p \|TSC2	V(75) = K(75,1) * [MAPK1_p] * [TSC2] -K(75,2) * [MAPK1_p \|TSC2];
R76	MAPK1_p \|TSC2	MAPK1_p + TSC2_p	MAPK1_p \|TSC2 → MAPK1_p + TSC2_p	V(76) = K(76,1) * [MAPK1_p \|TSC2];
R77	INSR_p + SIGNOR-C156	INSR_p \|SIGNOR-C156	INSR_p + SIGNOR-C156 → INSR_p \|SIGNOR-C156	V(77) = K(77,1) * [INSR_p] * [SIGNOR-C156] -K(77,2) * [INSR_p \|SIGNOR-C156];
R78	INSR_p \|SIGNOR-C156	INSR_p + SIGNOR-C156_p	INSR_p \|SIGNOR-C156 → INSR_p + SIGNOR-C156_p	V(78) = K(78,1) * [INSR_p \|SIGNOR-C156];
R79	MAPK1_p + RHOA	MAPK1_p \|RHOA	MAPK1_p + RHOA → MAPK1_p \|RHOA	V(79) = K(79,1) * [MAPK1_p] * [RHOA] -K(79,2) * [MAPK1_p \|RHOA];
R80	MAPK1_p \|RHOA	MAPK1_p + RHOA_p	MAPK1_p \|RHOA → MAPK1_p + RHOA_p	V(80) = K(80,1) * [MAPK1_p \|RHOA];
R81	CALM1 + EGFR_p	EGFR_p \|CALM1	CALM1 + EGFR_p → EGFR_p \|CALM1	V(81) = K(81,1) * [EGFR_p] * [CALM1] -K(81,2) * [EGFR_p \|CALM1];
R82	EGFR_p \|CALM1	CALM1_p + EGFR_p	EGFR_p \|CALM1 → CALM1_p + EGFR_p	V(82) = K(82,1) * [EGFR_p \|CALM1];
R83	PRKCA + PRKCA_p	PRKCA_p \|PRKCA	PRKCA + PRKCA_p → PRKCA_p \|PRKCA	V(83) = K(83,1) * [PRKCA_p] * [PRKCA] -K(83,2) * [PRKCA_p \|PRKCA];
R84	PRKCA_p \|PRKCA	PRKCA_p + PRKCA_p	PRKCA_p \|PRKCA → PRKCA_p + PRKCA_p	V(84) = K(84,1) * [PRKCA_p \|PRKCA];
R85	HMGN1 + PRKCA_p	PRKCA_p \|HMGN1	HMGN1 + PRKCA_p → PRKCA_p \|HMGN1	V(85) = K(85,1) * [PRKCA_p] * [HMGN1] -K(85,2) * [PRKCA_p \|HMGN1];
R86	PRKCA_p \|HMGN1	HMGN1_p + PRKCA_p	PRKCA_p \|HMGN1 → HMGN1_p + PRKCA_p	V(86) = K(86,1) * [PRKCA_p \|HMGN1];
R87	CALM1 + INSR_p	INSR_p \|CALM1	CALM1 + INSR_p → INSR_p \|CALM1	V(87) = K(87,1) * [INSR_p] * [CALM1] -K(87,2) * [INSR_p \|CALM1];
R88	INSR_p \|CALM1	CALM1_p + INSR_p	INSR_p \|CALM1 → CALM1_p + INSR_p	V(88) = K(88,1) * [INSR_p \|CALM1];
R89	CDKN1A + PRKCA_p	PRKCA_p \|CDKN1A	CDKN1A + PRKCA_p → PRKCA_p \|CDKN1A	V(89) = K(89,1) * [PRKCA_p] * [CDKN1A] -K(89,2) * [PRKCA_p \|CDKN1A];
R90	PRKCA_p \|CDKN1A	CDKN1A_p + PRKCA_p	PRKCA_p \|CDKN1A → CDKN1A_p + PRKCA_p	V(90) = K(90,1) * [PRKCA_p \|CDKN1A];
R91	ERN1 + ERN1_p	ERN1_p \|ERN1	ERN1 + ERN1_p → ERN1_p \|ERN1	V(91) = K(91,1) * [ERN1_p] * [ERN1] -K(91,2) * [ERN1_p \|ERN1];
R92	ERN1_p \|ERN1	ERN1_p + ERN1_p	ERN1_p \|ERN1 → ERN1_p + ERN1_p	V(92) = K(92,1) * [ERN1_p \|ERN1];
R93	DEPTOR + RPS6KA3_p	RPS6KA3_p \|DEPTOR	DEPTOR + RPS6KA3_p → RPS6KA3_p \|DEPTOR	V(93) = K(93,1) * [RPS6KA3_p] * [DEPTOR] -K(93,2) * [RPS6KA3_p \|DEPTOR];
R94	RPS6KA3_p \|DEPTOR	DEPTOR_p + RPS6KA3_p	RPS6KA3_p \|DEPTOR → DEPTOR_p + RPS6KA3_p	V(94) = K(94,1) * [RPS6KA3_p \|DEPTOR];
R95	AKT1_p + CDKN1B	AKT1_p \|CDKN1B	AKT1_p + CDKN1B → AKT1_p \|CDKN1B	V(95) = K(95,1) * [AKT1_p] * [CDKN1B] -K(95,2) * [AKT1_p \|CDKN1B];
R96	AKT1_p \|CDKN1B	AKT1_p + CDKN1B_p	AKT1_p \|CDKN1B → AKT1_p + CDKN1B_p	V(96) = K(96,1) * [AKT1_p \|CDKN1B];
R97	ATR + MDM2	ATR \|MDM2	ATR + MDM2 → ATR \|MDM2	V(97) = K(97,1) * [ATR] * [MDM2] -K(97,2) * [ATR \|MDM2];
R98	ATR \|MDM2	ATR + MDM2_p	ATR \|MDM2 → ATR + MDM2_p	V(98) = K(98,1) * [ATR \|MDM2];
R99	MAPK1_p + SIGNOR-C154	MAPK1_p \|SIGNOR-C154	MAPK1_p + SIGNOR-C154 → MAPK1_p \|SIGNOR-C154	V(99) = K(99,1) * [MAPK1_p] * [SIGNOR-C154] -K(99,2) * [MAPK1_p \|SIGNOR-C154];
R100	MAPK1_p \|SIGNOR-C154	MAPK1_p + SIGNOR-C154_p	MAPK1_p \|SIGNOR-C154 → MAPK1_p + SIGNOR-C154_p	V(100) = K(100,1) * [MAPK1_p \|SIGNOR-C154];
R101	BAD + RPS6KA3_p	RPS6KA3_p \|BAD	BAD + RPS6KA3_p → RPS6KA3_p \|BAD	V(101) = K(101,1) * [RPS6KA3_p] * [BAD] -K(101,2) * [RPS6KA3_p \|BAD];
R102	RPS6KA3_p \|BAD	BAD_p + RPS6KA3_p	RPS6KA3_p \|BAD → BAD_p + RPS6KA3_p	V(102) = K(102,1) * [RPS6KA3_p \|BAD];
R103	AKT1_p + RAC1	AKT1_p \|RAC1	AKT1_p + RAC1 → AKT1_p \|RAC1	V(103) = K(103,1) * [AKT1_p] * [RAC1] -K(103,2) * [AKT1_p \|RAC1];
R104	AKT1_p \|RAC1	AKT1_p + RAC1_p	AKT1_p \|RAC1 → AKT1_p + RAC1_p	V(104) = K(104,1) * [AKT1_p \|RAC1];
R105	PTEN + STK11_p	STK11_p \|PTEN	PTEN + STK11_p → STK11_p \|PTEN	V(105) = K(105,1) * [STK11_p] * [PTEN] -K(105,2) * [STK11_p \|PTEN];
R106	STK11_p \|PTEN	PTEN_p + STK11_p	STK11_p \|PTEN → PTEN_p + STK11_p	V(106) = K(106,1) * [STK11_p \|PTEN];
R107	HIPK2 + HIPK2_p	HIPK2_p \|HIPK2	HIPK2 + HIPK2_p → HIPK2_p \|HIPK2	V(107) = K(107,1) * [HIPK2_p] * [HIPK2] -K(107,2) * [HIPK2_p \|HIPK2];
R108	HIPK2_p \|HIPK2	HIPK2_p + HIPK2_p	HIPK2_p \|HIPK2 → HIPK2_p + HIPK2_p	V(108) = K(108,1) * [HIPK2_p \|HIPK2];
R109	CDKN1B + SGK1	SGK1 \|CDKN1B	CDKN1B + SGK1 → SGK1 \|CDKN1B	V(109) = K(109,1) * [SGK1] * [CDKN1B] -K(109,2) * [SGK1 \|CDKN1B];
R110	SGK1 \|CDKN1B	CDKN1B_p + SGK1	SGK1 \|CDKN1B → CDKN1B_p + SGK1	V(110) = K(110,1) * [SGK1 \|CDKN1B];
R111	CREB1 + RPS6KA3_p	RPS6KA3_p \|CREB1	CREB1 + RPS6KA3_p → RPS6KA3_p \|CREB1	V(111) = K(111,1) * [RPS6KA3_p] * [CREB1] -K(111,2) * [RPS6KA3_p \|CREB1];
R112	RPS6KA3_p \|CREB1	CREB1_p + RPS6KA3_p	RPS6KA3_p \|CREB1 → CREB1_p + RPS6KA3_p	V(112) = K(112,1) * [RPS6KA3_p \|CREB1];
R113	AKT1_p + TSC2	AKT1_p \|TSC2	AKT1_p + TSC2 → AKT1_p \|TSC2	V(113) = K(113,1) * [AKT1_p] * [TSC2] -K(113,2) * [AKT1_p \|TSC2];
R114	AKT1_p \|TSC2	AKT1_p + TSC2_p	AKT1_p \|TSC2 → AKT1_p + TSC2_p	V(114) = K(114,1) * [AKT1_p \|TSC2];
R115	PRKAA1 + PRKCA_p	PRKCA_p \|PRKAA1	PRKAA1 + PRKCA_p → PRKCA_p \|PRKAA1	V(115) = K(115,1) * [PRKCA_p] * [PRKAA1] -K(115,2) * [PRKCA_p \|PRKAA1];
R116	PRKCA_p \|PRKAA1	PRKAA1_p + PRKCA_p	PRKCA_p \|PRKAA1 → PRKAA1_p + PRKCA_p	V(116) = K(116,1) * [PRKCA_p \|PRKAA1];
R117	AKT1_p + EP300	AKT1_p \|EP300	AKT1_p + EP300 → AKT1_p \|EP300	V(117) = K(117,1) * [AKT1_p] * [EP300] -K(117,2) * [AKT1_p \|EP300];
R118	AKT1_p \|EP300	AKT1_p + EP300_p	AKT1_p \|EP300 → AKT1_p + EP300_p	V(118) = K(118,1) * [AKT1_p \|EP300];
R119	EGFR + MAPK1_p	MAPK1_p \|EGFR	EGFR + MAPK1_p → MAPK1_p \|EGFR	V(119) = K(119,1) * [MAPK1_p] * [EGFR] -K(119,2) * [MAPK1_p \|EGFR];
R120	MAPK1_p \|EGFR	EGFR_p + MAPK1_p	MAPK1_p \|EGFR → EGFR_p + MAPK1_p	V(120) = K(120,1) * [MAPK1_p \|EGFR];
R121	INSR + PRKCA_p	PRKCA_p \|INSR	INSR + PRKCA_p → PRKCA_p \|INSR	V(121) = K(121,1) * [PRKCA_p] * [INSR] -K(121,2) * [PRKCA_p \|INSR];
R122	PRKCA_p \|INSR	INSR_p + PRKCA_p	PRKCA_p \|INSR → INSR_p + PRKCA_p	V(122) = K(122,1) * [PRKCA_p \|INSR];
R123	BAD + SIGNOR-C156_p	SIGNOR-C156_p \|BAD	BAD + SIGNOR-C156_p → SIGNOR-C156_p \|BAD	V(123) = K(123,1) * [SIGNOR-C156_p] * [BAD] -K(123,2) * [SIGNOR-C156_p \|BAD];
R124	SIGNOR-C156_p \|BAD	BAD_p + SIGNOR-C156_p	SIGNOR-C156_p \|BAD → BAD_p + SIGNOR-C156_p	V(124) = K(124,1) * [SIGNOR-C156_p \|BAD];
R125	AKT1_p + VIM	AKT1_p \|VIM	AKT1_p + VIM → AKT1_p \|VIM	V(125) = K(125,1) * [AKT1_p] * [VIM] -K(125,2) * [AKT1_p \|VIM];
R126	AKT1_p \|VIM	AKT1_p + VIM_p	AKT1_p \|VIM → AKT1_p + VIM_p	V(126) = K(126,1) * [AKT1_p \|VIM];
R127	AXL + AXL_p	AXL_p \|AXL	AXL + AXL_p → AXL_p \|AXL	V(127) = K(127,1) * [AXL_p] * [AXL] -K(127,2) * [AXL_p \|AXL];
R128	AXL_p \|AXL	AXL_p + AXL_p	AXL_p \|AXL → AXL_p + AXL_p	V(128) = K(128,1) * [AXL_p \|AXL];
R129	DNMT1 + PRKAA1_p	PRKAA1_p \|DNMT1	DNMT1 + PRKAA1_p → PRKAA1_p \|DNMT1	V(129) = K(129,1) * [PRKAA1_p] * [DNMT1] -K(129,2) * [PRKAA1_p \|DNMT1];
R130	PRKAA1_p \|DNMT1	DNMT1_p + PRKAA1_p	PRKAA1_p \|DNMT1 → DNMT1_p + PRKAA1_p	V(130) = K(130,1) * [PRKAA1_p \|DNMT1];
R131	AKT1 + ILK_p	ILK_p \|AKT1	AKT1 + ILK_p → ILK_p \|AKT1	V(131) = K(131,1) * [ILK_p] * [AKT1] -K(131,2) * [ILK_p \|AKT1];
R132	ILK_p \|AKT1	AKT1_p + ILK_p	ILK_p \|AKT1 → AKT1_p + ILK_p	V(132) = K(132,1) * [ILK_p \|AKT1];
R133	MAPK1_p + SP1	MAPK1_p \|SP1	MAPK1_p + SP1 → MAPK1_p \|SP1	V(133) = K(133,1) * [MAPK1_p] * [SP1] -K(133,2) * [MAPK1_p \|SP1];
R134	MAPK1_p \|SP1	MAPK1_p + SP1_p	MAPK1_p \|SP1 → MAPK1_p + SP1_p	V(134) = K(134,1) * [MAPK1_p \|SP1];
R135	PTEN + ROCK1	ROCK1 \|PTEN	PTEN + ROCK1 → ROCK1 \|PTEN	V(135) = K(135,1) * [ROCK1] * [PTEN] -K(135,2) * [ROCK1 \|PTEN];
R136	ROCK1 \|PTEN	PTEN_p + ROCK1	ROCK1 \|PTEN → PTEN_p + ROCK1	V(136) = K(136,1) * [ROCK1 \|PTEN];
R137	BAD + MAPK1_p	MAPK1_p \|BAD	BAD + MAPK1_p → MAPK1_p \|BAD	V(137) = K(137,1) * [MAPK1_p] * [BAD] -K(137,2) * [MAPK1_p \|BAD];
R138	MAPK1_p \|BAD	BAD_p + MAPK1_p	MAPK1_p \|BAD → BAD_p + MAPK1_p	V(138) = K(138,1) * [MAPK1_p \|BAD];
R139	CDKN1A + MAPK1_p	MAPK1_p \|CDKN1A	CDKN1A + MAPK1_p → MAPK1_p \|CDKN1A	V(139) = K(139,1) * [MAPK1_p] * [CDKN1A] -K(139,2) * [MAPK1_p \|CDKN1A];
R140	MAPK1_p \|CDKN1A	CDKN1A_p + MAPK1_p	MAPK1_p \|CDKN1A → CDKN1A_p + MAPK1_p	V(140) = K(140,1) * [MAPK1_p \|CDKN1A];
R141	JAK1 + STAT3	JAK1 \|STAT3	JAK1 + STAT3 → JAK1 \|STAT3	V(141) = K(141,1) * [JAK1] * [STAT3] -K(141,2) * [JAK1 \|STAT3];
R142	JAK1 \|STAT3	JAK1 + STAT3_p	JAK1 \|STAT3 → JAK1 + STAT3_p	V(142) = K(142,1) * [JAK1 \|STAT3];
R143	AKT1_p + NR3C1	AKT1_p \|NR3C1	AKT1_p + NR3C1 → AKT1_p \|NR3C1	V(143) = K(143,1) * [AKT1_p] * [NR3C1] -K(143,2) * [AKT1_p \|NR3C1];
R144	AKT1_p \|NR3C1	AKT1_p + NR3C1_p	AKT1_p \|NR3C1 → AKT1_p + NR3C1_p	V(144) = K(144,1) * [AKT1_p \|NR3C1];
R145	HES1 + PRKCA_p	PRKCA_p \|HES1	HES1 + PRKCA_p → PRKCA_p \|HES1	V(145) = K(145,1) * [PRKCA_p] * [HES1] -K(145,2) * [PRKCA_p \|HES1];
R146	PRKCA_p \|HES1	HES1_p + PRKCA_p	PRKCA_p \|HES1 → HES1_p + PRKCA_p	V(146) = K(146,1) * [PRKCA_p \|HES1];
R147	EGFR_p + SIGNOR-C120	EGFR_p \|SIGNOR-C120	EGFR_p + SIGNOR-C120 → EGFR_p \|SIGNOR-C120	V(147) = K(147,1) * [EGFR_p] * [SIGNOR-C120] -K(147,2) * [EGFR_p \|SIGNOR-C120];
R148	EGFR_p \|SIGNOR-C120	EGFR_p + SIGNOR-C120_p	EGFR_p \|SIGNOR-C120 → EGFR_p + SIGNOR-C120_p	V(148) = K(148,1) * [EGFR_p \|SIGNOR-C120];
R149	SMAD4 + STK11_p	STK11_p \|SMAD4	SMAD4 + STK11_p → STK11_p \|SMAD4	V(149) = K(149,1) * [STK11_p] * [SMAD4] -K(149,2) * [STK11_p \|SMAD4];
R150	STK11_p \|SMAD4	SMAD4_p + STK11_p	STK11_p \|SMAD4 → SMAD4_p + STK11_p	V(150) = K(150,1) * [STK11_p \|SMAD4];
R151	ANXA1 + PRKCA_p	PRKCA_p \|ANXA1	ANXA1 + PRKCA_p → PRKCA_p \|ANXA1	V(151) = K(151,1) * [PRKCA_p] * [ANXA1] -K(151,2) * [PRKCA_p \|ANXA1];
R152	PRKCA_p \|ANXA1	ANXA1_p + PRKCA_p	PRKCA_p \|ANXA1 → ANXA1_p + PRKCA_p	V(152) = K(152,1) * [PRKCA_p \|ANXA1];
R153	AXL_p + EGFR	AXL_p \|EGFR	AXL_p + EGFR → AXL_p \|EGFR	V(153) = K(153,1) * [AXL_p] * [EGFR] -K(153,2) * [AXL_p \|EGFR];
R154	AXL_p \|EGFR	AXL_p + EGFR_p	AXL_p \|EGFR → AXL_p + EGFR_p	V(154) = K(154,1) * [AXL_p \|EGFR];
R155	JAK1 + STAT6	JAK1 \|STAT6	JAK1 + STAT6 → JAK1 \|STAT6	V(155) = K(155,1) * [JAK1] * [STAT6] -K(155,2) * [JAK1 \|STAT6];
R156	JAK1 \|STAT6	JAK1 + STAT6_p	JAK1 \|STAT6 → JAK1 + STAT6_p	V(156) = K(156,1) * [JAK1 \|STAT6];
R157	SGK1 + TSC2	SGK1 \|TSC2	SGK1 + TSC2 → SGK1 \|TSC2	V(157) = K(157,1) * [SGK1] * [TSC2] -K(157,2) * [SGK1 \|TSC2];
R158	SGK1 \|TSC2	SGK1 + TSC2_p	SGK1 \|TSC2 → SGK1 + TSC2_p	V(158) = K(158,1) * [SGK1 \|TSC2];
R159	AKT1_p + YAP1	AKT1_p \|YAP1	AKT1_p + YAP1 → AKT1_p \|YAP1	V(159) = K(159,1) * [AKT1_p] * [YAP1] -K(159,2) * [AKT1_p \|YAP1];
R160	AKT1_p \|YAP1	AKT1_p + YAP1_p	AKT1_p \|YAP1 → AKT1_p + YAP1_p	V(160) = K(160,1) * [AKT1_p \|YAP1];
R161	AKT1 + SIGNOR-C156_p	SIGNOR-C156_p \|AKT1	AKT1 + SIGNOR-C156_p → SIGNOR-C156_p \|AKT1	V(161) = K(161,1) * [SIGNOR-C156_p] * [AKT1] -K(161,2) * [SIGNOR-C156_p \|AKT1];
R162	SIGNOR-C156_p \|AKT1	AKT1_p + SIGNOR-C156_p	SIGNOR-C156_p \|AKT1 → AKT1_p + SIGNOR-C156_p	V(162) = K(162,1) * [SIGNOR-C156_p \|AKT1];
R163	FOS + RPS6KA3_p	RPS6KA3_p \|FOS	FOS + RPS6KA3_p → RPS6KA3_p \|FOS	V(163) = K(163,1) * [RPS6KA3_p] * [FOS] -K(163,2) * [RPS6KA3_p \|FOS];
R164	RPS6KA3_p \|FOS	FOS_p + RPS6KA3_p	RPS6KA3_p \|FOS → FOS_p + RPS6KA3_p	V(164) = K(164,1) * [RPS6KA3_p \|FOS];
R165	AKT1_p + RPS6KA3	AKT1_p \|RPS6KA3	AKT1_p + RPS6KA3 → AKT1_p \|RPS6KA3	V(165) = K(165,1) * [AKT1_p] * [RPS6KA3] -K(165,2) * [AKT1_p \|RPS6KA3];
R166	AKT1_p \|RPS6KA3	AKT1_p + RPS6KA3_p	AKT1_p \|RPS6KA3 → AKT1_p + RPS6KA3_p	V(166) = K(166,1) * [AKT1_p \|RPS6KA3];
R167	AKT1_p + DNMT1	AKT1_p \|DNMT1	AKT1_p + DNMT1 → AKT1_p \|DNMT1	V(167) = K(167,1) * [AKT1_p] * [DNMT1] -K(167,2) * [AKT1_p \|DNMT1];
R168	AKT1_p \|DNMT1	AKT1_p + DNMT1_p	AKT1_p \|DNMT1 → AKT1_p + DNMT1_p	V(168) = K(168,1) * [AKT1_p \|DNMT1];
R169	RPS6KA3 + RPS6KA3_p	RPS6KA3_p \|RPS6KA3	RPS6KA3 + RPS6KA3_p → RPS6KA3_p \|RPS6KA3	V(169) = K(169,1) * [RPS6KA3_p] * [RPS6KA3] -K(169,2) * [RPS6KA3_p \|RPS6KA3];
R170	RPS6KA3_p \|RPS6KA3	RPS6KA3_p + RPS6KA3_p	RPS6KA3_p \|RPS6KA3 → RPS6KA3_p + RPS6KA3_p	V(170) = K(170,1) * [RPS6KA3_p \|RPS6KA3];
R171	EP300 + PRKAA1_p	PRKAA1_p \|EP300	EP300 + PRKAA1_p → PRKAA1_p \|EP300	V(171) = K(171,1) * [PRKAA1_p] * [EP300] -K(171,2) * [PRKAA1_p \|EP300];
R172	PRKAA1_p \|EP300	EP300_p + PRKAA1_p	PRKAA1_p \|EP300 → EP300_p + PRKAA1_p	V(172) = K(172,1) * [PRKAA1_p \|EP300];
R173	HIPK2_p + MECP2	HIPK2_p \|MECP2	HIPK2_p + MECP2 → HIPK2_p \|MECP2	V(173) = K(173,1) * [HIPK2_p] * [MECP2] -K(173,2) * [HIPK2_p \|MECP2];
R174	HIPK2_p \|MECP2	HIPK2_p + MECP2_p	HIPK2_p \|MECP2 → HIPK2_p + MECP2_p	V(174) = K(174,1) * [HIPK2_p \|MECP2];
R175	AKT1_p + CTNNB1	AKT1_p \|CTNNB1	AKT1_p + CTNNB1 → AKT1_p \|CTNNB1	V(175) = K(175,1) * [AKT1_p] * [CTNNB1] -K(175,2) * [AKT1_p \|CTNNB1];
R176	AKT1_p \|CTNNB1	AKT1_p + CTNNB1_p	AKT1_p \|CTNNB1 → AKT1_p + CTNNB1_p	V(176) = K(176,1) * [AKT1_p \|CTNNB1];
R177	CYBA + PRKCA_p	PRKCA_p \|CYBA	CYBA + PRKCA_p → PRKCA_p \|CYBA	V(177) = K(177,1) * [PRKCA_p] * [CYBA] -K(177,2) * [PRKCA_p \|CYBA];
R178	PRKCA_p \|CYBA	CYBA_p + PRKCA_p	PRKCA_p \|CYBA → CYBA_p + PRKCA_p	V(178) = K(178,1) * [PRKCA_p \|CYBA];
R179	ESR1 + RPS6KA3_p	RPS6KA3_p \|ESR1	ESR1 + RPS6KA3_p → RPS6KA3_p \|ESR1	V(179) = K(179,1) * [RPS6KA3_p] * [ESR1] -K(179,2) * [RPS6KA3_p \|ESR1];
R180	RPS6KA3_p \|ESR1	ESR1_p + RPS6KA3_p	RPS6KA3_p \|ESR1 → ESR1_p + RPS6KA3_p	V(180) = K(180,1) * [RPS6KA3_p \|ESR1];
R181	NR4A1 + RPS6KA3_p	RPS6KA3_p \|NR4A1	NR4A1 + RPS6KA3_p → RPS6KA3_p \|NR4A1	V(181) = K(181,1) * [RPS6KA3_p] * [NR4A1] -K(181,2) * [RPS6KA3_p \|NR4A1];
R182	RPS6KA3_p \|NR4A1	NR4A1_p + RPS6KA3_p	RPS6KA3_p \|NR4A1 → NR4A1_p + RPS6KA3_p	V(182) = K(182,1) * [RPS6KA3_p \|NR4A1];
R183	BAD + PRKCA_p	PRKCA_p \|BAD	BAD + PRKCA_p → PRKCA_p \|BAD	V(183) = K(183,1) * [PRKCA_p] * [BAD] -K(183,2) * [PRKCA_p \|BAD];
R184	PRKCA_p \|BAD	BAD_p + PRKCA_p	PRKCA_p \|BAD → BAD_p + PRKCA_p	V(184) = K(184,1) * [PRKCA_p \|BAD];
R185	STK11_p + YAP1	STK11_p \|YAP1	STK11_p + YAP1 → STK11_p \|YAP1	V(185) = K(185,1) * [STK11_p] * [YAP1] -K(185,2) * [STK11_p \|YAP1];
R186	STK11_p \|YAP1	STK11_p + YAP1_p	STK11_p \|YAP1 → STK11_p + YAP1_p	V(186) = K(186,1) * [STK11_p \|YAP1];
R187	MAPK1 + MAPK1_p	MAPK1_p \|MAPK1	MAPK1 + MAPK1_p → MAPK1_p \|MAPK1	V(187) = K(187,1) * [MAPK1_p] * [MAPK1] -K(187,2) * [MAPK1_p \|MAPK1];
R188	MAPK1_p \|MAPK1	MAPK1_p + MAPK1_p	MAPK1_p \|MAPK1 → MAPK1_p + MAPK1_p	V(188) = K(188,1) * [MAPK1_p \|MAPK1];
R189	PRKAA1_p + TSC2	PRKAA1_p \|TSC2	PRKAA1_p + TSC2 → PRKAA1_p \|TSC2	V(189) = K(189,1) * [PRKAA1_p] * [TSC2] -K(189,2) * [PRKAA1_p \|TSC2];
R190	PRKAA1_p \|TSC2	PRKAA1_p + TSC2_p	PRKAA1_p \|TSC2 → PRKAA1_p + TSC2_p	V(190) = K(190,1) * [PRKAA1_p \|TSC2];
R191	MAPK1_p + ZFP36	MAPK1_p \|ZFP36	MAPK1_p + ZFP36 → MAPK1_p \|ZFP36	V(191) = K(191,1) * [MAPK1_p] * [ZFP36] -K(191,2) * [MAPK1_p \|ZFP36];
R192	MAPK1_p \|ZFP36	MAPK1_p + ZFP36_p	MAPK1_p \|ZFP36 → MAPK1_p + ZFP36_p	V(192) = K(192,1) * [MAPK1_p \|ZFP36];
R193	MAPK1_p + RCAN1	MAPK1_p \|RCAN1	MAPK1_p + RCAN1 → MAPK1_p \|RCAN1	V(193) = K(193,1) * [MAPK1_p] * [RCAN1] -K(193,2) * [MAPK1_p \|RCAN1];
R194	MAPK1_p \|RCAN1	MAPK1_p + RCAN1_p	MAPK1_p \|RCAN1 → MAPK1_p + RCAN1_p	V(194) = K(194,1) * [MAPK1_p \|RCAN1];
R195	EGFR + PKN1_p	PKN1_p \|EGFR	EGFR + PKN1_p → PKN1_p \|EGFR	V(195) = K(195,1) * [PKN1_p] * [EGFR] -K(195,2) * [PKN1_p \|EGFR];
R196	PKN1_p \|EGFR	EGFR_p + PKN1_p	PKN1_p \|EGFR → EGFR_p + PKN1_p	V(196) = K(196,1) * [PKN1_p \|EGFR];
R197	AEBP1 + MAPK1_p	MAPK1_p \|AEBP1	AEBP1 + MAPK1_p → MAPK1_p \|AEBP1	V(197) = K(197,1) * [MAPK1_p] * [AEBP1] -K(197,2) * [MAPK1_p \|AEBP1];
R198	MAPK1_p \|AEBP1	AEBP1_p + MAPK1_p	MAPK1_p \|AEBP1 → AEBP1_p + MAPK1_p	V(198) = K(198,1) * [MAPK1_p \|AEBP1];
R199	EGFR_p + ESR1	EGFR_p \|ESR1	EGFR_p + ESR1 → EGFR_p \|ESR1	V(199) = K(199,1) * [EGFR_p] * [ESR1] -K(199,2) * [EGFR_p \|ESR1];