ConnectingTubule_SPADANReactionsTable

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Reaction ID	Reactants	Products	Original Text	ODE Equations
R1	SMAD3_p + SMAD4_p	SIGNOR-C9	SMAD3_p + SMAD4_p → SIGNOR-C9	V(1) = K(1,1) * [SMAD4_p] * [SMAD3_p] -K(1,2) * [SIGNOR-C9];
R2	JUN_p + SMAD4_p	SIGNOR-C10	JUN_p + SMAD4_p → SIGNOR-C10	V(2) = K(2,1) * [SMAD4_p] * [JUN_p] -K(2,2) * [SIGNOR-C10];
R3	SMAD1 + SMAD1 + SMAD4_p	SIGNOR-C85	SMAD1 + SMAD1 + SMAD4_p → SIGNOR-C85	V(3) = K(3,1) * [SMAD4_p] * [SMAD1] * [SMAD1] -K(3,2) * [SIGNOR-C85];
R4	JUN_p + SMAD3_p	SIGNOR-C86	JUN_p + SMAD3_p → SIGNOR-C86	V(4) = K(4,1) * [JUN_p] * [SMAD3_p] -K(4,2) * [SIGNOR-C86];
R5	FOS_p + FOS_p + FOS_p + FOS_p + JUN_p + JUN_p + JUN_p + JUN_p	SIGNOR-C154	FOS_p + FOS_p + FOS_p + FOS_p + JUN_p + JUN_p + JUN_p + JUN_p → SIGNOR-C154	V(5) = K(5,1) * [FOS_p] * [JUN_p] * [JUN_p] * [FOS_p] * [JUN_p] * [FOS_p] * [FOS_p] * [JUN_p] -K(5,2) * [SIGNOR-C154];
R6	HIF1A + MAPK1_p	MAPK1_p \|HIF1A	HIF1A + MAPK1_p → MAPK1_p \|HIF1A	V(6) = K(6,1) * [MAPK1_p] * [HIF1A] -K(6,2) * [MAPK1_p \|HIF1A];
R7	MAPK1_p \|HIF1A	HIF1A_p + MAPK1_p	MAPK1_p \|HIF1A → HIF1A_p + MAPK1_p	V(7) = K(7,1) * [MAPK1_p \|HIF1A];
R8	MAPK1_p + NR3C1	MAPK1_p \|NR3C1	MAPK1_p + NR3C1 → MAPK1_p \|NR3C1	V(8) = K(8,1) * [MAPK1_p] * [NR3C1] -K(8,2) * [MAPK1_p \|NR3C1];
R9	MAPK1_p \|NR3C1	MAPK1_p + NR3C1_p	MAPK1_p \|NR3C1 → MAPK1_p + NR3C1_p	V(9) = K(9,1) * [MAPK1_p \|NR3C1];
R10	MAPK1_p + RPS6KA3	MAPK1_p \|RPS6KA3	MAPK1_p + RPS6KA3 → MAPK1_p \|RPS6KA3	V(10) = K(10,1) * [MAPK1_p] * [RPS6KA3] -K(10,2) * [MAPK1_p \|RPS6KA3];
R11	MAPK1_p \|RPS6KA3	MAPK1_p + RPS6KA3_p	MAPK1_p \|RPS6KA3 → MAPK1_p + RPS6KA3_p	V(11) = K(11,1) * [MAPK1_p \|RPS6KA3];
R12	AKT1_p + FOXO1	AKT1_p \|FOXO1	AKT1_p + FOXO1 → AKT1_p \|FOXO1	V(12) = K(12,1) * [AKT1_p] * [FOXO1] -K(12,2) * [AKT1_p \|FOXO1];
R13	AKT1_p \|FOXO1	AKT1_p + FOXO1_p	AKT1_p \|FOXO1 → AKT1_p + FOXO1_p	V(13) = K(13,1) * [AKT1_p \|FOXO1];
R14	RPS6KA3 + SRC_p	SRC_p \|RPS6KA3	RPS6KA3 + SRC_p → SRC_p \|RPS6KA3	V(14) = K(14,1) * [SRC_p] * [RPS6KA3] -K(14,2) * [SRC_p \|RPS6KA3];
R15	SRC_p \|RPS6KA3	RPS6KA3_p + SRC_p	SRC_p \|RPS6KA3 → RPS6KA3_p + SRC_p	V(15) = K(15,1) * [SRC_p \|RPS6KA3];
R16	MAPK1_p + SMAD1	MAPK1_p \|SMAD1	MAPK1_p + SMAD1 → MAPK1_p \|SMAD1	V(16) = K(16,1) * [MAPK1_p] * [SMAD1] -K(16,2) * [MAPK1_p \|SMAD1];
R17	MAPK1_p \|SMAD1	MAPK1_p + SMAD1_p	MAPK1_p \|SMAD1 → MAPK1_p + SMAD1_p	V(17) = K(17,1) * [MAPK1_p \|SMAD1];
R18	SRC_p + TP53	SRC_p \|TP53	SRC_p + TP53 → SRC_p \|TP53	V(18) = K(18,1) * [SRC_p] * [TP53] -K(18,2) * [SRC_p \|TP53];
R19	SRC_p \|TP53	SRC_p + TP53_p	SRC_p \|TP53 → SRC_p + TP53_p	V(19) = K(19,1) * [SRC_p \|TP53];
R20	AKT1_p + PRKAA1	AKT1_p \|PRKAA1	AKT1_p + PRKAA1 → AKT1_p \|PRKAA1	V(20) = K(20,1) * [AKT1_p] * [PRKAA1] -K(20,2) * [AKT1_p \|PRKAA1];
R21	AKT1_p \|PRKAA1	AKT1_p + PRKAA1_p	AKT1_p \|PRKAA1 → AKT1_p + PRKAA1_p	V(21) = K(21,1) * [AKT1_p \|PRKAA1];
R22	EGFR + EGFR_p	EGFR_p \|EGFR	EGFR + EGFR_p → EGFR_p \|EGFR	V(22) = K(22,1) * [EGFR_p] * [EGFR] -K(22,2) * [EGFR_p \|EGFR];
R23	EGFR_p \|EGFR	EGFR_p + EGFR_p	EGFR_p \|EGFR → EGFR_p + EGFR_p	V(23) = K(23,1) * [EGFR_p \|EGFR];
R24	JAK2 + JAK2_p	JAK2_p \|JAK2	JAK2 + JAK2_p → JAK2_p \|JAK2	V(24) = K(24,1) * [JAK2_p] * [JAK2] -K(24,2) * [JAK2_p \|JAK2];
R25	JAK2_p \|JAK2	JAK2_p + JAK2_p	JAK2_p \|JAK2 → JAK2_p + JAK2_p	V(25) = K(25,1) * [JAK2_p \|JAK2];
R26	CDKN1B + MAPK1_p	MAPK1_p \|CDKN1B	CDKN1B + MAPK1_p → MAPK1_p \|CDKN1B	V(26) = K(26,1) * [MAPK1_p] * [CDKN1B] -K(26,2) * [MAPK1_p \|CDKN1B];
R27	MAPK1_p \|CDKN1B	CDKN1B_p + MAPK1_p	MAPK1_p \|CDKN1B → CDKN1B_p + MAPK1_p	V(27) = K(27,1) * [MAPK1_p \|CDKN1B];
R28	MAPK1_p + SMAD4	MAPK1_p \|SMAD4	MAPK1_p + SMAD4 → MAPK1_p \|SMAD4	V(28) = K(28,1) * [MAPK1_p] * [SMAD4] -K(28,2) * [MAPK1_p \|SMAD4];
R29	MAPK1_p \|SMAD4	MAPK1_p + SMAD4_p	MAPK1_p \|SMAD4 → MAPK1_p + SMAD4_p	V(29) = K(29,1) * [MAPK1_p \|SMAD4];
R30	JUN + MAPK1_p	MAPK1_p \|JUN	JUN + MAPK1_p → MAPK1_p \|JUN	V(30) = K(30,1) * [MAPK1_p] * [JUN] -K(30,2) * [MAPK1_p \|JUN];
R31	MAPK1_p \|JUN	JUN_p + MAPK1_p	MAPK1_p \|JUN → JUN_p + MAPK1_p	V(31) = K(31,1) * [MAPK1_p \|JUN];
R32	AKT1_p + NR4A1	AKT1_p \|NR4A1	AKT1_p + NR4A1 → AKT1_p \|NR4A1	V(32) = K(32,1) * [AKT1_p] * [NR4A1] -K(32,2) * [AKT1_p \|NR4A1];
R33	AKT1_p \|NR4A1	AKT1_p + NR4A1_p	AKT1_p \|NR4A1 → AKT1_p + NR4A1_p	V(33) = K(33,1) * [AKT1_p \|NR4A1];
R34	JAK2_p + MAP3K5	JAK2_p \|MAP3K5	JAK2_p + MAP3K5 → JAK2_p \|MAP3K5	V(34) = K(34,1) * [JAK2_p] * [MAP3K5] -K(34,2) * [JAK2_p \|MAP3K5];
R35	JAK2_p \|MAP3K5	JAK2_p + MAP3K5_p	JAK2_p \|MAP3K5 → JAK2_p + MAP3K5_p	V(35) = K(35,1) * [JAK2_p \|MAP3K5];
R36	FOS + MAPK1_p	MAPK1_p \|FOS	FOS + MAPK1_p → MAPK1_p \|FOS	V(36) = K(36,1) * [MAPK1_p] * [FOS] -K(36,2) * [MAPK1_p \|FOS];
R37	MAPK1_p \|FOS	FOS_p + MAPK1_p	MAPK1_p \|FOS → FOS_p + MAPK1_p	V(37) = K(37,1) * [MAPK1_p \|FOS];
R38	SRC + SRC_p	SRC_p \|SRC	SRC + SRC_p → SRC_p \|SRC	V(38) = K(38,1) * [SRC_p] * [SRC] -K(38,2) * [SRC_p \|SRC];
R39	SRC_p \|SRC	SRC_p + SRC_p	SRC_p \|SRC → SRC_p + SRC_p	V(39) = K(39,1) * [SRC_p \|SRC];
R40	SRC_p + TLR3	SRC_p \|TLR3	SRC_p + TLR3 → SRC_p \|TLR3	V(40) = K(40,1) * [SRC_p] * [TLR3] -K(40,2) * [SRC_p \|TLR3];
R41	SRC_p \|TLR3	SRC_p + TLR3_p	SRC_p \|TLR3 → SRC_p + TLR3_p	V(41) = K(41,1) * [SRC_p \|TLR3];
R42	CTNNB1 + KIT_p	KIT_p \|CTNNB1	CTNNB1 + KIT_p → KIT_p \|CTNNB1	V(42) = K(42,1) * [KIT_p] * [CTNNB1] -K(42,2) * [KIT_p \|CTNNB1];
R43	KIT_p \|CTNNB1	CTNNB1_p + KIT_p	KIT_p \|CTNNB1 → CTNNB1_p + KIT_p	V(43) = K(43,1) * [KIT_p \|CTNNB1];
R44	JAK1_p + STAT1	JAK1_p \|STAT1	JAK1_p + STAT1 → JAK1_p \|STAT1	V(44) = K(44,1) * [JAK1_p] * [STAT1] -K(44,2) * [JAK1_p \|STAT1];
R45	JAK1_p \|STAT1	JAK1_p + STAT1_p	JAK1_p \|STAT1 → JAK1_p + STAT1_p	V(45) = K(45,1) * [JAK1_p \|STAT1];
R46	DUSP1 + MAPK1_p	MAPK1_p \|DUSP1	DUSP1 + MAPK1_p → MAPK1_p \|DUSP1	V(46) = K(46,1) * [MAPK1_p] * [DUSP1] -K(46,2) * [MAPK1_p \|DUSP1];
R47	MAPK1_p \|DUSP1	DUSP1_p + MAPK1_p	MAPK1_p \|DUSP1 → DUSP1_p + MAPK1_p	V(47) = K(47,1) * [MAPK1_p \|DUSP1];
R48	AKT1_p + HSPB1	AKT1_p \|HSPB1	AKT1_p + HSPB1 → AKT1_p \|HSPB1	V(48) = K(48,1) * [AKT1_p] * [HSPB1] -K(48,2) * [AKT1_p \|HSPB1];
R49	AKT1_p \|HSPB1	AKT1_p + HSPB1_p	AKT1_p \|HSPB1 → AKT1_p + HSPB1_p	V(49) = K(49,1) * [AKT1_p \|HSPB1];
R50	PKN1 + PKN1_p	PKN1_p \|PKN1	PKN1 + PKN1_p → PKN1_p \|PKN1	V(50) = K(50,1) * [PKN1_p] * [PKN1] -K(50,2) * [PKN1_p \|PKN1];
R51	PKN1_p \|PKN1	PKN1_p + PKN1_p	PKN1_p \|PKN1 → PKN1_p + PKN1_p	V(51) = K(51,1) * [PKN1_p \|PKN1];
R52	AKT1_p + CDKN1A	AKT1_p \|CDKN1A	AKT1_p + CDKN1A → AKT1_p \|CDKN1A	V(52) = K(52,1) * [AKT1_p] * [CDKN1A] -K(52,2) * [AKT1_p \|CDKN1A];
R53	AKT1_p \|CDKN1A	AKT1_p + CDKN1A_p	AKT1_p \|CDKN1A → AKT1_p + CDKN1A_p	V(53) = K(53,1) * [AKT1_p \|CDKN1A];
R54	AKT1 + SRC_p	SRC_p \|AKT1	AKT1 + SRC_p → SRC_p \|AKT1	V(54) = K(54,1) * [SRC_p] * [AKT1] -K(54,2) * [SRC_p \|AKT1];
R55	SRC_p \|AKT1	AKT1_p + SRC_p	SRC_p \|AKT1 → AKT1_p + SRC_p	V(55) = K(55,1) * [SRC_p \|AKT1];
R56	EIF2AK3 + JAK1_p	JAK1_p \|EIF2AK3	EIF2AK3 + JAK1_p → JAK1_p \|EIF2AK3	V(56) = K(56,1) * [JAK1_p] * [EIF2AK3] -K(56,2) * [JAK1_p \|EIF2AK3];
R57	JAK1_p \|EIF2AK3	EIF2AK3_p + JAK1_p	JAK1_p \|EIF2AK3 → EIF2AK3_p + JAK1_p	V(57) = K(57,1) * [JAK1_p \|EIF2AK3];
R58	MAPK1_p + SPHK1	MAPK1_p \|SPHK1	MAPK1_p + SPHK1 → MAPK1_p \|SPHK1	V(58) = K(58,1) * [MAPK1_p] * [SPHK1] -K(58,2) * [MAPK1_p \|SPHK1];
R59	MAPK1_p \|SPHK1	MAPK1_p + SPHK1_p	MAPK1_p \|SPHK1 → MAPK1_p + SPHK1_p	V(59) = K(59,1) * [MAPK1_p \|SPHK1];
R60	KIT + KIT_p	KIT_p \|KIT	KIT + KIT_p → KIT_p \|KIT	V(60) = K(60,1) * [KIT_p] * [KIT] -K(60,2) * [KIT_p \|KIT];
R61	KIT_p \|KIT	KIT_p + KIT_p	KIT_p \|KIT → KIT_p + KIT_p	V(61) = K(61,1) * [KIT_p \|KIT];
R62	MAPK1_p + RHOA	MAPK1_p \|RHOA	MAPK1_p + RHOA → MAPK1_p \|RHOA	V(62) = K(62,1) * [MAPK1_p] * [RHOA] -K(62,2) * [MAPK1_p \|RHOA];
R63	MAPK1_p \|RHOA	MAPK1_p + RHOA_p	MAPK1_p \|RHOA → MAPK1_p + RHOA_p	V(63) = K(63,1) * [MAPK1_p \|RHOA];
R64	EPOR + JAK2_p	JAK2_p \|EPOR	EPOR + JAK2_p → JAK2_p \|EPOR	V(64) = K(64,1) * [JAK2_p] * [EPOR] -K(64,2) * [JAK2_p \|EPOR];
R65	JAK2_p \|EPOR	EPOR_p + JAK2_p	JAK2_p \|EPOR → EPOR_p + JAK2_p	V(65) = K(65,1) * [JAK2_p \|EPOR];
R66	FOXO1 + MAPK1_p	MAPK1_p \|FOXO1	FOXO1 + MAPK1_p → MAPK1_p \|FOXO1	V(66) = K(66,1) * [MAPK1_p] * [FOXO1] -K(66,2) * [MAPK1_p \|FOXO1];
R67	MAPK1_p \|FOXO1	FOXO1_p + MAPK1_p	MAPK1_p \|FOXO1 → FOXO1_p + MAPK1_p	V(67) = K(67,1) * [MAPK1_p \|FOXO1];
R68	JAK2_p + STAT1	JAK2_p \|STAT1	JAK2_p + STAT1 → JAK2_p \|STAT1	V(68) = K(68,1) * [JAK2_p] * [STAT1] -K(68,2) * [JAK2_p \|STAT1];
R69	JAK2_p \|STAT1	JAK2_p + STAT1_p	JAK2_p \|STAT1 → JAK2_p + STAT1_p	V(69) = K(69,1) * [JAK2_p \|STAT1];
R70	EGFR + SRC_p	SRC_p \|EGFR	EGFR + SRC_p → SRC_p \|EGFR	V(70) = K(70,1) * [SRC_p] * [EGFR] -K(70,2) * [SRC_p \|EGFR];
R71	SRC_p \|EGFR	EGFR_p + SRC_p	SRC_p \|EGFR → EGFR_p + SRC_p	V(71) = K(71,1) * [SRC_p \|EGFR];
R72	SRC_p + STAT1	SRC_p \|STAT1	SRC_p + STAT1 → SRC_p \|STAT1	V(72) = K(72,1) * [SRC_p] * [STAT1] -K(72,2) * [SRC_p \|STAT1];
R73	SRC_p \|STAT1	SRC_p + STAT1_p	SRC_p \|STAT1 → SRC_p + STAT1_p	V(73) = K(73,1) * [SRC_p \|STAT1];
R74	MAPK1_p + SMAD3	MAPK1_p \|SMAD3	MAPK1_p + SMAD3 → MAPK1_p \|SMAD3	V(74) = K(74,1) * [MAPK1_p] * [SMAD3] -K(74,2) * [MAPK1_p \|SMAD3];
R75	MAPK1_p \|SMAD3	MAPK1_p + SMAD3_p	MAPK1_p \|SMAD3 → MAPK1_p + SMAD3_p	V(75) = K(75,1) * [MAPK1_p \|SMAD3];
R76	ERN1 + ERN1_p	ERN1_p \|ERN1	ERN1 + ERN1_p → ERN1_p \|ERN1	V(76) = K(76,1) * [ERN1_p] * [ERN1] -K(76,2) * [ERN1_p \|ERN1];
R77	ERN1_p \|ERN1	ERN1_p + ERN1_p	ERN1_p \|ERN1 → ERN1_p + ERN1_p	V(77) = K(77,1) * [ERN1_p \|ERN1];
R78	DEPTOR + RPS6KA3_p	RPS6KA3_p \|DEPTOR	DEPTOR + RPS6KA3_p → RPS6KA3_p \|DEPTOR	V(78) = K(78,1) * [RPS6KA3_p] * [DEPTOR] -K(78,2) * [RPS6KA3_p \|DEPTOR];
R79	RPS6KA3_p \|DEPTOR	DEPTOR_p + RPS6KA3_p	RPS6KA3_p \|DEPTOR → DEPTOR_p + RPS6KA3_p	V(79) = K(79,1) * [RPS6KA3_p \|DEPTOR];
R80	MAP3K5 + RPS6KA3_p	RPS6KA3_p \|MAP3K5	MAP3K5 + RPS6KA3_p → RPS6KA3_p \|MAP3K5	V(80) = K(80,1) * [RPS6KA3_p] * [MAP3K5] -K(80,2) * [RPS6KA3_p \|MAP3K5];
R81	RPS6KA3_p \|MAP3K5	MAP3K5_p + RPS6KA3_p	RPS6KA3_p \|MAP3K5 → MAP3K5_p + RPS6KA3_p	V(81) = K(81,1) * [RPS6KA3_p \|MAP3K5];
R82	AKT1_p + CDKN1B	AKT1_p \|CDKN1B	AKT1_p + CDKN1B → AKT1_p \|CDKN1B	V(82) = K(82,1) * [AKT1_p] * [CDKN1B] -K(82,2) * [AKT1_p \|CDKN1B];
R83	AKT1_p \|CDKN1B	AKT1_p + CDKN1B_p	AKT1_p \|CDKN1B → AKT1_p + CDKN1B_p	V(83) = K(83,1) * [AKT1_p \|CDKN1B];
R84	IGF1R + SRC_p	SRC_p \|IGF1R	IGF1R + SRC_p → SRC_p \|IGF1R	V(84) = K(84,1) * [SRC_p] * [IGF1R] -K(84,2) * [SRC_p \|IGF1R];
R85	SRC_p \|IGF1R	IGF1R_p + SRC_p	SRC_p \|IGF1R → IGF1R_p + SRC_p	V(85) = K(85,1) * [SRC_p \|IGF1R];
R86	MAPK1_p + SIGNOR-C154	MAPK1_p \|SIGNOR-C154	MAPK1_p + SIGNOR-C154 → MAPK1_p \|SIGNOR-C154	V(86) = K(86,1) * [MAPK1_p] * [SIGNOR-C154] -K(86,2) * [MAPK1_p \|SIGNOR-C154];
R87	MAPK1_p \|SIGNOR-C154	MAPK1_p + SIGNOR-C154_p	MAPK1_p \|SIGNOR-C154 → MAPK1_p + SIGNOR-C154_p	V(87) = K(87,1) * [MAPK1_p \|SIGNOR-C154];
R88	IGF1R + IGF1R_p	IGF1R_p \|IGF1R	IGF1R + IGF1R_p → IGF1R_p \|IGF1R	V(88) = K(88,1) * [IGF1R_p] * [IGF1R] -K(88,2) * [IGF1R_p \|IGF1R];
R89	IGF1R_p \|IGF1R	IGF1R_p + IGF1R_p	IGF1R_p \|IGF1R → IGF1R_p + IGF1R_p	V(89) = K(89,1) * [IGF1R_p \|IGF1R];
R90	FOXO1 + SGK1	SGK1 \|FOXO1	FOXO1 + SGK1 → SGK1 \|FOXO1	V(90) = K(90,1) * [SGK1] * [FOXO1] -K(90,2) * [SGK1 \|FOXO1];
R91	SGK1 \|FOXO1	FOXO1_p + SGK1	SGK1 \|FOXO1 → FOXO1_p + SGK1	V(91) = K(91,1) * [SGK1 \|FOXO1];
R92	CDKN1B + SGK1	SGK1 \|CDKN1B	CDKN1B + SGK1 → SGK1 \|CDKN1B	V(92) = K(92,1) * [SGK1] * [CDKN1B] -K(92,2) * [SGK1 \|CDKN1B];
R93	SGK1 \|CDKN1B	CDKN1B_p + SGK1	SGK1 \|CDKN1B → CDKN1B_p + SGK1	V(93) = K(93,1) * [SGK1 \|CDKN1B];
R94	CREB1 + RPS6KA3_p	RPS6KA3_p \|CREB1	CREB1 + RPS6KA3_p → RPS6KA3_p \|CREB1	V(94) = K(94,1) * [RPS6KA3_p] * [CREB1] -K(94,2) * [RPS6KA3_p \|CREB1];
R95	RPS6KA3_p \|CREB1	CREB1_p + RPS6KA3_p	RPS6KA3_p \|CREB1 → CREB1_p + RPS6KA3_p	V(95) = K(95,1) * [RPS6KA3_p \|CREB1];
R96	EGFR + MAPK1_p	MAPK1_p \|EGFR	EGFR + MAPK1_p → MAPK1_p \|EGFR	V(96) = K(96,1) * [MAPK1_p] * [EGFR] -K(96,2) * [MAPK1_p \|EGFR];
R97	MAPK1_p \|EGFR	EGFR_p + MAPK1_p	MAPK1_p \|EGFR → EGFR_p + MAPK1_p	V(97) = K(97,1) * [MAPK1_p \|EGFR];
R98	PTEN + SRC_p	SRC_p \|PTEN	PTEN + SRC_p → SRC_p \|PTEN	V(98) = K(98,1) * [SRC_p] * [PTEN] -K(98,2) * [SRC_p \|PTEN];
R99	SRC_p \|PTEN	PTEN_p + SRC_p	SRC_p \|PTEN → PTEN_p + SRC_p	V(99) = K(99,1) * [SRC_p \|PTEN];
R100	EIF2AK3 + EIF2AK3_p	EIF2AK3_p \|EIF2AK3	EIF2AK3 + EIF2AK3_p → EIF2AK3_p \|EIF2AK3	V(100) = K(100,1) * [EIF2AK3_p] * [EIF2AK3] -K(100,2) * [EIF2AK3_p \|EIF2AK3];
R101	EIF2AK3_p \|EIF2AK3	EIF2AK3_p + EIF2AK3_p	EIF2AK3_p \|EIF2AK3 → EIF2AK3_p + EIF2AK3_p	V(101) = K(101,1) * [EIF2AK3_p \|EIF2AK3];
R102	MAP3K5 + MAP3K5_p	MAP3K5_p \|MAP3K5	MAP3K5 + MAP3K5_p → MAP3K5_p \|MAP3K5	V(102) = K(102,1) * [MAP3K5_p] * [MAP3K5] -K(102,2) * [MAP3K5_p \|MAP3K5];
R103	MAP3K5_p \|MAP3K5	MAP3K5_p + MAP3K5_p	MAP3K5_p \|MAP3K5 → MAP3K5_p + MAP3K5_p	V(103) = K(103,1) * [MAP3K5_p \|MAP3K5];
R104	AKT1_p + VIM	AKT1_p \|VIM	AKT1_p + VIM → AKT1_p \|VIM	V(104) = K(104,1) * [AKT1_p] * [VIM] -K(104,2) * [AKT1_p \|VIM];
R105	AKT1_p \|VIM	AKT1_p + VIM_p	AKT1_p \|VIM → AKT1_p + VIM_p	V(105) = K(105,1) * [AKT1_p \|VIM];
R106	AKT1 + ILK_p	ILK_p \|AKT1	AKT1 + ILK_p → ILK_p \|AKT1	V(106) = K(106,1) * [ILK_p] * [AKT1] -K(106,2) * [ILK_p \|AKT1];
R107	ILK_p \|AKT1	AKT1_p + ILK_p	ILK_p \|AKT1 → AKT1_p + ILK_p	V(107) = K(107,1) * [ILK_p \|AKT1];
R108	MAPK1_p + SP1	MAPK1_p \|SP1	MAPK1_p + SP1 → MAPK1_p \|SP1	V(108) = K(108,1) * [MAPK1_p] * [SP1] -K(108,2) * [MAPK1_p \|SP1];
R109	MAPK1_p \|SP1	MAPK1_p + SP1_p	MAPK1_p \|SP1 → MAPK1_p + SP1_p	V(109) = K(109,1) * [MAPK1_p \|SP1];
R110	PTEN + ROCK1	ROCK1 \|PTEN	PTEN + ROCK1 → ROCK1 \|PTEN	V(110) = K(110,1) * [ROCK1] * [PTEN] -K(110,2) * [ROCK1 \|PTEN];
R111	ROCK1 \|PTEN	PTEN_p + ROCK1	ROCK1 \|PTEN → PTEN_p + ROCK1	V(111) = K(111,1) * [ROCK1 \|PTEN];
R112	CDKN1A + MAPK1_p	MAPK1_p \|CDKN1A	CDKN1A + MAPK1_p → MAPK1_p \|CDKN1A	V(112) = K(112,1) * [MAPK1_p] * [CDKN1A] -K(112,2) * [MAPK1_p \|CDKN1A];
R113	MAPK1_p \|CDKN1A	CDKN1A_p + MAPK1_p	MAPK1_p \|CDKN1A → CDKN1A_p + MAPK1_p	V(113) = K(113,1) * [MAPK1_p \|CDKN1A];
R114	FOXO1 + PRKAA1	PRKAA1 \|FOXO1	FOXO1 + PRKAA1 → PRKAA1 \|FOXO1	V(114) = K(114,1) * [PRKAA1] * [FOXO1] -K(114,2) * [PRKAA1 \|FOXO1];
R115	PRKAA1 \|FOXO1	FOXO1_p + PRKAA1	PRKAA1 \|FOXO1 → FOXO1_p + PRKAA1	V(115) = K(115,1) * [PRKAA1 \|FOXO1];
R116	JAK2 + MAPK1_p	MAPK1_p \|JAK2	JAK2 + MAPK1_p → MAPK1_p \|JAK2	V(116) = K(116,1) * [MAPK1_p] * [JAK2] -K(116,2) * [MAPK1_p \|JAK2];
R117	MAPK1_p \|JAK2	JAK2_p + MAPK1_p	MAPK1_p \|JAK2 → JAK2_p + MAPK1_p	V(117) = K(117,1) * [MAPK1_p \|JAK2];
R118	IGF1R_p + PCNA	IGF1R_p \|PCNA	IGF1R_p + PCNA → IGF1R_p \|PCNA	V(118) = K(118,1) * [IGF1R_p] * [PCNA] -K(118,2) * [IGF1R_p \|PCNA];
R119	IGF1R_p \|PCNA	IGF1R_p + PCNA_p	IGF1R_p \|PCNA → IGF1R_p + PCNA_p	V(119) = K(119,1) * [IGF1R_p \|PCNA];
R120	AKT1_p + CASP9	AKT1_p \|CASP9	AKT1_p + CASP9 → AKT1_p \|CASP9	V(120) = K(120,1) * [AKT1_p] * [CASP9] -K(120,2) * [AKT1_p \|CASP9];
R121	AKT1_p \|CASP9	AKT1_p + CASP9_p	AKT1_p \|CASP9 → AKT1_p + CASP9_p	V(121) = K(121,1) * [AKT1_p \|CASP9];
R122	AKT1_p + NR3C1	AKT1_p \|NR3C1	AKT1_p + NR3C1 → AKT1_p \|NR3C1	V(122) = K(122,1) * [AKT1_p] * [NR3C1] -K(122,2) * [AKT1_p \|NR3C1];
R123	AKT1_p \|NR3C1	AKT1_p + NR3C1_p	AKT1_p \|NR3C1 → AKT1_p + NR3C1_p	V(123) = K(123,1) * [AKT1_p \|NR3C1];
R124	CLTC + SRC_p	SRC_p \|CLTC	CLTC + SRC_p → SRC_p \|CLTC	V(124) = K(124,1) * [SRC_p] * [CLTC] -K(124,2) * [SRC_p \|CLTC];
R125	SRC_p \|CLTC	CLTC_p + SRC_p	SRC_p \|CLTC → CLTC_p + SRC_p	V(125) = K(125,1) * [SRC_p \|CLTC];
R126	JAK2_p + STAT6	JAK2_p \|STAT6	JAK2_p + STAT6 → JAK2_p \|STAT6	V(126) = K(126,1) * [JAK2_p] * [STAT6] -K(126,2) * [JAK2_p \|STAT6];
R127	JAK2_p \|STAT6	JAK2_p + STAT6_p	JAK2_p \|STAT6 → JAK2_p + STAT6_p	V(127) = K(127,1) * [JAK2_p \|STAT6];
R128	MAP3K14_p + NFKB2	MAP3K14_p \|NFKB2	MAP3K14_p + NFKB2 → MAP3K14_p \|NFKB2	V(128) = K(128,1) * [MAP3K14_p] * [NFKB2] -K(128,2) * [MAP3K14_p \|NFKB2];
R129	MAP3K14_p \|NFKB2	MAP3K14_p + NFKB2_p	MAP3K14_p \|NFKB2 → MAP3K14_p + NFKB2_p	V(129) = K(129,1) * [MAP3K14_p \|NFKB2];
R130	FOXO1 + PKN1_p	PKN1_p \|FOXO1	FOXO1 + PKN1_p → PKN1_p \|FOXO1	V(130) = K(130,1) * [PKN1_p] * [FOXO1] -K(130,2) * [PKN1_p \|FOXO1];
R131	PKN1_p \|FOXO1	FOXO1_p + PKN1_p	PKN1_p \|FOXO1 → FOXO1_p + PKN1_p	V(131) = K(131,1) * [PKN1_p \|FOXO1];
R132	CASP9 + MAPK1_p	MAPK1_p \|CASP9	CASP9 + MAPK1_p → MAPK1_p \|CASP9	V(132) = K(132,1) * [MAPK1_p] * [CASP9] -K(132,2) * [MAPK1_p \|CASP9];
R133	MAPK1_p \|CASP9	CASP9_p + MAPK1_p	MAPK1_p \|CASP9 → CASP9_p + MAPK1_p	V(133) = K(133,1) * [MAPK1_p \|CASP9];
R134	MAP3K14 + MAP3K14_p	MAP3K14_p \|MAP3K14	MAP3K14 + MAP3K14_p → MAP3K14_p \|MAP3K14	V(134) = K(134,1) * [MAP3K14_p] * [MAP3K14] -K(134,2) * [MAP3K14_p \|MAP3K14];
R135	MAP3K14_p \|MAP3K14	MAP3K14_p + MAP3K14_p	MAP3K14_p \|MAP3K14 → MAP3K14_p + MAP3K14_p	V(135) = K(135,1) * [MAP3K14_p \|MAP3K14];
R136	JAK1_p + STAT6	JAK1_p \|STAT6	JAK1_p + STAT6 → JAK1_p \|STAT6	V(136) = K(136,1) * [JAK1_p] * [STAT6] -K(136,2) * [JAK1_p \|STAT6];
R137	JAK1_p \|STAT6	JAK1_p + STAT6_p	JAK1_p \|STAT6 → JAK1_p + STAT6_p	V(137) = K(137,1) * [JAK1_p \|STAT6];
R138	AKT1_p + YAP1	AKT1_p \|YAP1	AKT1_p + YAP1 → AKT1_p \|YAP1	V(138) = K(138,1) * [AKT1_p] * [YAP1] -K(138,2) * [AKT1_p \|YAP1];
R139	AKT1_p \|YAP1	AKT1_p + YAP1_p	AKT1_p \|YAP1 → AKT1_p + YAP1_p	V(139) = K(139,1) * [AKT1_p \|YAP1];
R140	CDKN1B + JAK2_p	JAK2_p \|CDKN1B	CDKN1B + JAK2_p → JAK2_p \|CDKN1B	V(140) = K(140,1) * [JAK2_p] * [CDKN1B] -K(140,2) * [JAK2_p \|CDKN1B];
R141	JAK2_p \|CDKN1B	CDKN1B_p + JAK2_p	JAK2_p \|CDKN1B → CDKN1B_p + JAK2_p	V(141) = K(141,1) * [JAK2_p \|CDKN1B];
R142	SMAD1 + SMAD4	SMAD1 \|SMAD4	SMAD1 + SMAD4 → SMAD1 \|SMAD4	V(142) = K(142,1) * [SMAD1] * [SMAD4] -K(142,2) * [SMAD1 \|SMAD4];
R143	SMAD1 \|SMAD4	SMAD1 + SMAD4_p	SMAD1 \|SMAD4 → SMAD1 + SMAD4_p	V(143) = K(143,1) * [SMAD1 \|SMAD4];
R144	FOS + RPS6KA3_p	RPS6KA3_p \|FOS	FOS + RPS6KA3_p → RPS6KA3_p \|FOS	V(144) = K(144,1) * [RPS6KA3_p] * [FOS] -K(144,2) * [RPS6KA3_p \|FOS];
R145	RPS6KA3_p \|FOS	FOS_p + RPS6KA3_p	RPS6KA3_p \|FOS → FOS_p + RPS6KA3_p	V(145) = K(145,1) * [RPS6KA3_p \|FOS];
R146	AKT1_p + RPS6KA3	AKT1_p \|RPS6KA3	AKT1_p + RPS6KA3 → AKT1_p \|RPS6KA3	V(146) = K(146,1) * [AKT1_p] * [RPS6KA3] -K(146,2) * [AKT1_p \|RPS6KA3];
R147	AKT1_p \|RPS6KA3	AKT1_p + RPS6KA3_p	AKT1_p \|RPS6KA3 → AKT1_p + RPS6KA3_p	V(147) = K(147,1) * [AKT1_p \|RPS6KA3];
R148	KIT_p + STAT1	KIT_p \|STAT1	KIT_p + STAT1 → KIT_p \|STAT1	V(148) = K(148,1) * [KIT_p] * [STAT1] -K(148,2) * [KIT_p \|STAT1];
R149	KIT_p \|STAT1	KIT_p + STAT1_p	KIT_p \|STAT1 → KIT_p + STAT1_p	V(149) = K(149,1) * [KIT_p \|STAT1];
R150	RPS6KA3 + RPS6KA3_p	RPS6KA3_p \|RPS6KA3	RPS6KA3 + RPS6KA3_p → RPS6KA3_p \|RPS6KA3	V(150) = K(150,1) * [RPS6KA3_p] * [RPS6KA3] -K(150,2) * [RPS6KA3_p \|RPS6KA3];
R151	RPS6KA3_p \|RPS6KA3	RPS6KA3_p + RPS6KA3_p	RPS6KA3_p \|RPS6KA3 → RPS6KA3_p + RPS6KA3_p	V(151) = K(151,1) * [RPS6KA3_p \|RPS6KA3];
R152	AKT1_p + CTNNB1	AKT1_p \|CTNNB1	AKT1_p + CTNNB1 → AKT1_p \|CTNNB1	V(152) = K(152,1) * [AKT1_p] * [CTNNB1] -K(152,2) * [AKT1_p \|CTNNB1];
R153	AKT1_p \|CTNNB1	AKT1_p + CTNNB1_p	AKT1_p \|CTNNB1 → AKT1_p + CTNNB1_p	V(153) = K(153,1) * [AKT1_p \|CTNNB1];
R154	NR4A1 + RPS6KA3_p	RPS6KA3_p \|NR4A1	NR4A1 + RPS6KA3_p → RPS6KA3_p \|NR4A1	V(154) = K(154,1) * [RPS6KA3_p] * [NR4A1] -K(154,2) * [RPS6KA3_p \|NR4A1];
R155	RPS6KA3_p \|NR4A1	NR4A1_p + RPS6KA3_p	RPS6KA3_p \|NR4A1 → NR4A1_p + RPS6KA3_p	V(155) = K(155,1) * [RPS6KA3_p \|NR4A1];
R156	ROCK1 + TP53	ROCK1 \|TP53	ROCK1 + TP53 → ROCK1 \|TP53	V(156) = K(156,1) * [ROCK1] * [TP53] -K(156,2) * [ROCK1 \|TP53];
R157	ROCK1 \|TP53	ROCK1 + TP53_p	ROCK1 \|TP53 → ROCK1 + TP53_p	V(157) = K(157,1) * [ROCK1 \|TP53];
R158	AKT1_p + RUNX2	AKT1_p \|RUNX2	AKT1_p + RUNX2 → AKT1_p \|RUNX2	V(158) = K(158,1) * [AKT1_p] * [RUNX2] -K(158,2) * [AKT1_p \|RUNX2];
R159	AKT1_p \|RUNX2	AKT1_p + RUNX2_p	AKT1_p \|RUNX2 → AKT1_p + RUNX2_p	V(159) = K(159,1) * [AKT1_p \|RUNX2];
R160	MAPK1 + MAPK1_p	MAPK1_p \|MAPK1	MAPK1 + MAPK1_p → MAPK1_p \|MAPK1	V(160) = K(160,1) * [MAPK1_p] * [MAPK1] -K(160,2) * [MAPK1_p \|MAPK1];
R161	MAPK1_p \|MAPK1	MAPK1_p + MAPK1_p	MAPK1_p \|MAPK1 → MAPK1_p + MAPK1_p	V(161) = K(161,1) * [MAPK1_p \|MAPK1];
R162	MAPK1_p + RRAS	MAPK1_p \|RRAS	MAPK1_p + RRAS → MAPK1_p \|RRAS	V(162) = K(162,1) * [MAPK1_p] * [RRAS] -K(162,2) * [MAPK1_p \|RRAS];
R163	MAPK1_p \|RRAS	MAPK1_p + RRAS_p	MAPK1_p \|RRAS → MAPK1_p + RRAS_p	V(163) = K(163,1) * [MAPK1_p \|RRAS];
R164	CDH1 + SRC_p	SRC_p \|CDH1	CDH1 + SRC_p → SRC_p \|CDH1	V(164) = K(164,1) * [SRC_p] * [CDH1] -K(164,2) * [SRC_p \|CDH1];
R165	SRC_p \|CDH1	CDH1_p + SRC_p	SRC_p \|CDH1 → CDH1_p + SRC_p	V(165) = K(165,1) * [SRC_p \|CDH1];
R166	MAPK1_p + ZFP36	MAPK1_p \|ZFP36	MAPK1_p + ZFP36 → MAPK1_p \|ZFP36	V(166) = K(166,1) * [MAPK1_p] * [ZFP36] -K(166,2) * [MAPK1_p \|ZFP36];
R167	MAPK1_p \|ZFP36	MAPK1_p + ZFP36_p	MAPK1_p \|ZFP36 → MAPK1_p + ZFP36_p	V(167) = K(167,1) * [MAPK1_p \|ZFP36];
R168	MAPK1_p + RCAN1	MAPK1_p \|RCAN1	MAPK1_p + RCAN1 → MAPK1_p \|RCAN1	V(168) = K(168,1) * [MAPK1_p] * [RCAN1] -K(168,2) * [MAPK1_p \|RCAN1];
R169	MAPK1_p \|RCAN1	MAPK1_p + RCAN1_p	MAPK1_p \|RCAN1 → MAPK1_p + RCAN1_p	V(169) = K(169,1) * [MAPK1_p \|RCAN1];
R170	EGFR + JAK2_p	JAK2_p \|EGFR	EGFR + JAK2_p → JAK2_p \|EGFR	V(170) = K(170,1) * [JAK2_p] * [EGFR] -K(170,2) * [JAK2_p \|EGFR];
R171	JAK2_p \|EGFR	EGFR_p + JAK2_p	JAK2_p \|EGFR → EGFR_p + JAK2_p	V(171) = K(171,1) * [JAK2_p \|EGFR];
R172	EGFR + PKN1_p	PKN1_p \|EGFR	EGFR + PKN1_p → PKN1_p \|EGFR	V(172) = K(172,1) * [PKN1_p] * [EGFR] -K(172,2) * [PKN1_p \|EGFR];
R173	PKN1_p \|EGFR	EGFR_p + PKN1_p	PKN1_p \|EGFR → EGFR_p + PKN1_p	V(173) = K(173,1) * [PKN1_p \|EGFR];
R174	AKT1_p + MAP3K5	AKT1_p \|MAP3K5	AKT1_p + MAP3K5 → AKT1_p \|MAP3K5	V(174) = K(174,1) * [AKT1_p] * [MAP3K5] -K(174,2) * [AKT1_p \|MAP3K5];
R175	AKT1_p \|MAP3K5	AKT1_p + MAP3K5_p	AKT1_p \|MAP3K5 → AKT1_p + MAP3K5_p	V(175) = K(175,1) * [AKT1_p \|MAP3K5];
R176	AKT1_p + PARK7	AKT1_p \|PARK7	AKT1_p + PARK7 → AKT1_p \|PARK7	V(176) = K(176,1) * [AKT1_p] * [PARK7] -K(176,2) * [AKT1_p \|PARK7];
R177	AKT1_p \|PARK7	AKT1_p + PARK7_p	AKT1_p \|PARK7 → AKT1_p + PARK7_p	V(177) = K(177,1) * [AKT1_p \|PARK7];
R178	KIT + SRC_p	SRC_p \|KIT	KIT + SRC_p → SRC_p \|KIT	V(178) = K(178,1) * [SRC_p] * [KIT] -K(178,2) * [SRC_p \|KIT];
R179	SRC_p \|KIT	KIT_p + SRC_p	SRC_p \|KIT → KIT_p + SRC_p	V(179) = K(179,1) * [SRC_p \|KIT];
R180	SGK1 + SP1	SGK1 \|SP1	SGK1 + SP1 → SGK1 \|SP1	V(180) = K(180,1) * [SGK1] * [SP1] -K(180,2) * [SGK1 \|SP1];
R181	SGK1 \|SP1	SGK1 + SP1_p	SGK1 \|SP1 → SGK1 + SP1_p	V(181) = K(181,1) * [SGK1 \|SP1];
R182	PROM1 + SRC_p	SRC_p \|PROM1	PROM1 + SRC_p → SRC_p \|PROM1	V(182) = K(182,1) * [SRC_p] * [PROM1] -K(182,2) * [SRC_p \|PROM1];
R183	SRC_p \|PROM1	PROM1_p + SRC_p	SRC_p \|PROM1 → PROM1_p + SRC_p	V(183) = K(183,1) * [SRC_p \|PROM1];
R184	CTNNB1 + SRC_p	SRC_p \|CTNNB1	CTNNB1 + SRC_p → SRC_p \|CTNNB1	V(184) = K(184,1) * [SRC_p] * [CTNNB1] -K(184,2) * [SRC_p \|CTNNB1];
R185	SRC_p \|CTNNB1	CTNNB1_p + SRC_p	SRC_p \|CTNNB1 → CTNNB1_p + SRC_p	V(185) = K(185,1) * [SRC_p \|CTNNB1];
R186	MAPK1 + SGK1	SGK1 \|MAPK1	MAPK1 + SGK1 → SGK1 \|MAPK1	V(186) = K(186,1) * [SGK1] * [MAPK1] -K(186,2) * [SGK1 \|MAPK1];
R187	SGK1 \|MAPK1	MAPK1_p + SGK1	SGK1 \|MAPK1 → MAPK1_p + SGK1	V(187) = K(187,1) * [SGK1 \|MAPK1];
R188	GHR + JAK2_p	JAK2_p \|GHR	GHR + JAK2_p → JAK2_p \|GHR	V(188) = K(188,1) * [JAK2_p] * [GHR] -K(188,2) * [JAK2_p \|GHR];
R189	JAK2_p \|GHR	GHR_p + JAK2_p	JAK2_p \|GHR → GHR_p + JAK2_p	V(189) = K(189,1) * [JAK2_p \|GHR];
R190	DDIT3 + PRKAA1	PRKAA1 \|DDIT3	DDIT3 + PRKAA1 → PRKAA1 \|DDIT3	V(190) = K(190,1) * [PRKAA1] * [DDIT3] -K(190,2) * [PRKAA1 \|DDIT3];
R191	PRKAA1 \|DDIT3	DDIT3_p + PRKAA1	PRKAA1 \|DDIT3 → DDIT3_p + PRKAA1	V(191) = K(191,1) * [PRKAA1 \|DDIT3];
R192	RPS6KA3_p + TP53	RPS6KA3_p \|TP53	RPS6KA3_p + TP53 → RPS6KA3_p \|TP53	V(192) = K(192,1) * [RPS6KA3_p] * [TP53] -K(192,2) * [RPS6KA3_p \|TP53];
R193	RPS6KA3_p \|TP53	RPS6KA3_p + TP53_p	RPS6KA3_p \|TP53 → RPS6KA3_p + TP53_p	V(193) = K(193,1) * [RPS6KA3_p \|TP53];
R194	MYD88 + SRC_p	SRC_p \|MYD88	MYD88 + SRC_p → SRC_p \|MYD88	V(194) = K(194,1) * [SRC_p] * [MYD88] -K(194,2) * [SRC_p \|MYD88];
R195	SRC_p \|MYD88	MYD88_p + SRC_p	SRC_p \|MYD88 → MYD88_p + SRC_p	V(195) = K(195,1) * [SRC_p \|MYD88];
R196	MAPK1_p + XBP1	MAPK1_p \|XBP1	MAPK1_p + XBP1 → MAPK1_p \|XBP1	V(196) = K(196,1) * [MAPK1_p] * [XBP1] -K(196,2) * [MAPK1_p \|XBP1];
R197	MAPK1_p \|XBP1	MAPK1_p + XBP1_p	MAPK1_p \|XBP1 → MAPK1_p + XBP1_p	V(197) = K(197,1) * [MAPK1_p \|XBP1];
R198	NR3C1 + SGK1	SGK1 \|NR3C1	NR3C1 + SGK1 → SGK1 \|NR3C1	V(198) = K(198,1) * [SGK1] * [NR3C1] -K(198,2) * [SGK1 \|NR3C1];
R199	SGK1 \|NR3C1	NR3C1_p + SGK1	SGK1 \|NR3C1 → NR3C1_p + SGK1	V(199) = K(199,1) * [SGK1 \|NR3C1];

Reaction ID	Reactants	Products	Original Text	ODE Equations
R1	SMAD3_p + SMAD4_p	SIGNOR-C9	SMAD3_p + SMAD4_p → SIGNOR-C9	V(1) = K(1,1) * [SMAD4_p] * [SMAD3_p] -K(1,2) * [SIGNOR-C9];
R2	JUN_p + SMAD4_p	SIGNOR-C10	JUN_p + SMAD4_p → SIGNOR-C10	V(2) = K(2,1) * [SMAD4_p] * [JUN_p] -K(2,2) * [SIGNOR-C10];
R3	SMAD1 + SMAD1 + SMAD4_p	SIGNOR-C85	SMAD1 + SMAD1 + SMAD4_p → SIGNOR-C85	V(3) = K(3,1) * [SMAD4_p] * [SMAD1] * [SMAD1] -K(3,2) * [SIGNOR-C85];
R4	JUN_p + SMAD3_p	SIGNOR-C86	JUN_p + SMAD3_p → SIGNOR-C86	V(4) = K(4,1) * [JUN_p] * [SMAD3_p] -K(4,2) * [SIGNOR-C86];
R5	FOS_p + FOS_p + FOS_p + FOS_p + JUN_p + JUN_p + JUN_p + JUN_p	SIGNOR-C154	FOS_p + FOS_p + FOS_p + FOS_p + JUN_p + JUN_p + JUN_p + JUN_p → SIGNOR-C154	V(5) = K(5,1) * [FOS_p] * [JUN_p] * [JUN_p] * [FOS_p] * [JUN_p] * [FOS_p] * [FOS_p] * [JUN_p] -K(5,2) * [SIGNOR-C154];
R6	HIF1A + MAPK1_p	MAPK1_p \|HIF1A	HIF1A + MAPK1_p → MAPK1_p \|HIF1A	V(6) = K(6,1) * [MAPK1_p] * [HIF1A] -K(6,2) * [MAPK1_p \|HIF1A];
R7	MAPK1_p \|HIF1A	HIF1A_p + MAPK1_p	MAPK1_p \|HIF1A → HIF1A_p + MAPK1_p	V(7) = K(7,1) * [MAPK1_p \|HIF1A];
R8	MAPK1_p + NR3C1	MAPK1_p \|NR3C1	MAPK1_p + NR3C1 → MAPK1_p \|NR3C1	V(8) = K(8,1) * [MAPK1_p] * [NR3C1] -K(8,2) * [MAPK1_p \|NR3C1];
R9	MAPK1_p \|NR3C1	MAPK1_p + NR3C1_p	MAPK1_p \|NR3C1 → MAPK1_p + NR3C1_p	V(9) = K(9,1) * [MAPK1_p \|NR3C1];
R10	MAPK1_p + RPS6KA3	MAPK1_p \|RPS6KA3	MAPK1_p + RPS6KA3 → MAPK1_p \|RPS6KA3	V(10) = K(10,1) * [MAPK1_p] * [RPS6KA3] -K(10,2) * [MAPK1_p \|RPS6KA3];
R11	MAPK1_p \|RPS6KA3	MAPK1_p + RPS6KA3_p	MAPK1_p \|RPS6KA3 → MAPK1_p + RPS6KA3_p	V(11) = K(11,1) * [MAPK1_p \|RPS6KA3];
R12	AKT1_p + FOXO1	AKT1_p \|FOXO1	AKT1_p + FOXO1 → AKT1_p \|FOXO1	V(12) = K(12,1) * [AKT1_p] * [FOXO1] -K(12,2) * [AKT1_p \|FOXO1];
R13	AKT1_p \|FOXO1	AKT1_p + FOXO1_p	AKT1_p \|FOXO1 → AKT1_p + FOXO1_p	V(13) = K(13,1) * [AKT1_p \|FOXO1];
R14	RPS6KA3 + SRC_p	SRC_p \|RPS6KA3	RPS6KA3 + SRC_p → SRC_p \|RPS6KA3	V(14) = K(14,1) * [SRC_p] * [RPS6KA3] -K(14,2) * [SRC_p \|RPS6KA3];
R15	SRC_p \|RPS6KA3	RPS6KA3_p + SRC_p	SRC_p \|RPS6KA3 → RPS6KA3_p + SRC_p	V(15) = K(15,1) * [SRC_p \|RPS6KA3];
R16	MAPK1_p + SMAD1	MAPK1_p \|SMAD1	MAPK1_p + SMAD1 → MAPK1_p \|SMAD1	V(16) = K(16,1) * [MAPK1_p] * [SMAD1] -K(16,2) * [MAPK1_p \|SMAD1];
R17	MAPK1_p \|SMAD1	MAPK1_p + SMAD1_p	MAPK1_p \|SMAD1 → MAPK1_p + SMAD1_p	V(17) = K(17,1) * [MAPK1_p \|SMAD1];
R18	SRC_p + TP53	SRC_p \|TP53	SRC_p + TP53 → SRC_p \|TP53	V(18) = K(18,1) * [SRC_p] * [TP53] -K(18,2) * [SRC_p \|TP53];
R19	SRC_p \|TP53	SRC_p + TP53_p	SRC_p \|TP53 → SRC_p + TP53_p	V(19) = K(19,1) * [SRC_p \|TP53];
R20	AKT1_p + PRKAA1	AKT1_p \|PRKAA1	AKT1_p + PRKAA1 → AKT1_p \|PRKAA1	V(20) = K(20,1) * [AKT1_p] * [PRKAA1] -K(20,2) * [AKT1_p \|PRKAA1];
R21	AKT1_p \|PRKAA1	AKT1_p + PRKAA1_p	AKT1_p \|PRKAA1 → AKT1_p + PRKAA1_p	V(21) = K(21,1) * [AKT1_p \|PRKAA1];
R22	EGFR + EGFR_p	EGFR_p \|EGFR	EGFR + EGFR_p → EGFR_p \|EGFR	V(22) = K(22,1) * [EGFR_p] * [EGFR] -K(22,2) * [EGFR_p \|EGFR];
R23	EGFR_p \|EGFR	EGFR_p + EGFR_p	EGFR_p \|EGFR → EGFR_p + EGFR_p	V(23) = K(23,1) * [EGFR_p \|EGFR];
R24	JAK2 + JAK2_p	JAK2_p \|JAK2	JAK2 + JAK2_p → JAK2_p \|JAK2	V(24) = K(24,1) * [JAK2_p] * [JAK2] -K(24,2) * [JAK2_p \|JAK2];
R25	JAK2_p \|JAK2	JAK2_p + JAK2_p	JAK2_p \|JAK2 → JAK2_p + JAK2_p	V(25) = K(25,1) * [JAK2_p \|JAK2];
R26	CDKN1B + MAPK1_p	MAPK1_p \|CDKN1B	CDKN1B + MAPK1_p → MAPK1_p \|CDKN1B	V(26) = K(26,1) * [MAPK1_p] * [CDKN1B] -K(26,2) * [MAPK1_p \|CDKN1B];
R27	MAPK1_p \|CDKN1B	CDKN1B_p + MAPK1_p	MAPK1_p \|CDKN1B → CDKN1B_p + MAPK1_p	V(27) = K(27,1) * [MAPK1_p \|CDKN1B];
R28	MAPK1_p + SMAD4	MAPK1_p \|SMAD4	MAPK1_p + SMAD4 → MAPK1_p \|SMAD4	V(28) = K(28,1) * [MAPK1_p] * [SMAD4] -K(28,2) * [MAPK1_p \|SMAD4];
R29	MAPK1_p \|SMAD4	MAPK1_p + SMAD4_p	MAPK1_p \|SMAD4 → MAPK1_p + SMAD4_p	V(29) = K(29,1) * [MAPK1_p \|SMAD4];
R30	JUN + MAPK1_p	MAPK1_p \|JUN	JUN + MAPK1_p → MAPK1_p \|JUN	V(30) = K(30,1) * [MAPK1_p] * [JUN] -K(30,2) * [MAPK1_p \|JUN];
R31	MAPK1_p \|JUN	JUN_p + MAPK1_p	MAPK1_p \|JUN → JUN_p + MAPK1_p	V(31) = K(31,1) * [MAPK1_p \|JUN];
R32	AKT1_p + NR4A1	AKT1_p \|NR4A1	AKT1_p + NR4A1 → AKT1_p \|NR4A1	V(32) = K(32,1) * [AKT1_p] * [NR4A1] -K(32,2) * [AKT1_p \|NR4A1];
R33	AKT1_p \|NR4A1	AKT1_p + NR4A1_p	AKT1_p \|NR4A1 → AKT1_p + NR4A1_p	V(33) = K(33,1) * [AKT1_p \|NR4A1];
R34	JAK2_p + MAP3K5	JAK2_p \|MAP3K5	JAK2_p + MAP3K5 → JAK2_p \|MAP3K5	V(34) = K(34,1) * [JAK2_p] * [MAP3K5] -K(34,2) * [JAK2_p \|MAP3K5];
R35	JAK2_p \|MAP3K5	JAK2_p + MAP3K5_p	JAK2_p \|MAP3K5 → JAK2_p + MAP3K5_p	V(35) = K(35,1) * [JAK2_p \|MAP3K5];
R36	FOS + MAPK1_p	MAPK1_p \|FOS	FOS + MAPK1_p → MAPK1_p \|FOS	V(36) = K(36,1) * [MAPK1_p] * [FOS] -K(36,2) * [MAPK1_p \|FOS];
R37	MAPK1_p \|FOS	FOS_p + MAPK1_p	MAPK1_p \|FOS → FOS_p + MAPK1_p	V(37) = K(37,1) * [MAPK1_p \|FOS];
R38	SRC + SRC_p	SRC_p \|SRC	SRC + SRC_p → SRC_p \|SRC	V(38) = K(38,1) * [SRC_p] * [SRC] -K(38,2) * [SRC_p \|SRC];
R39	SRC_p \|SRC	SRC_p + SRC_p	SRC_p \|SRC → SRC_p + SRC_p	V(39) = K(39,1) * [SRC_p \|SRC];
R40	SRC_p + TLR3	SRC_p \|TLR3	SRC_p + TLR3 → SRC_p \|TLR3	V(40) = K(40,1) * [SRC_p] * [TLR3] -K(40,2) * [SRC_p \|TLR3];
R41	SRC_p \|TLR3	SRC_p + TLR3_p	SRC_p \|TLR3 → SRC_p + TLR3_p	V(41) = K(41,1) * [SRC_p \|TLR3];
R42	CTNNB1 + KIT_p	KIT_p \|CTNNB1	CTNNB1 + KIT_p → KIT_p \|CTNNB1	V(42) = K(42,1) * [KIT_p] * [CTNNB1] -K(42,2) * [KIT_p \|CTNNB1];
R43	KIT_p \|CTNNB1	CTNNB1_p + KIT_p	KIT_p \|CTNNB1 → CTNNB1_p + KIT_p	V(43) = K(43,1) * [KIT_p \|CTNNB1];
R44	JAK1_p + STAT1	JAK1_p \|STAT1	JAK1_p + STAT1 → JAK1_p \|STAT1	V(44) = K(44,1) * [JAK1_p] * [STAT1] -K(44,2) * [JAK1_p \|STAT1];
R45	JAK1_p \|STAT1	JAK1_p + STAT1_p	JAK1_p \|STAT1 → JAK1_p + STAT1_p	V(45) = K(45,1) * [JAK1_p \|STAT1];
R46	DUSP1 + MAPK1_p	MAPK1_p \|DUSP1	DUSP1 + MAPK1_p → MAPK1_p \|DUSP1	V(46) = K(46,1) * [MAPK1_p] * [DUSP1] -K(46,2) * [MAPK1_p \|DUSP1];
R47	MAPK1_p \|DUSP1	DUSP1_p + MAPK1_p	MAPK1_p \|DUSP1 → DUSP1_p + MAPK1_p	V(47) = K(47,1) * [MAPK1_p \|DUSP1];
R48	AKT1_p + HSPB1	AKT1_p \|HSPB1	AKT1_p + HSPB1 → AKT1_p \|HSPB1	V(48) = K(48,1) * [AKT1_p] * [HSPB1] -K(48,2) * [AKT1_p \|HSPB1];
R49	AKT1_p \|HSPB1	AKT1_p + HSPB1_p	AKT1_p \|HSPB1 → AKT1_p + HSPB1_p	V(49) = K(49,1) * [AKT1_p \|HSPB1];
R50	PKN1 + PKN1_p	PKN1_p \|PKN1	PKN1 + PKN1_p → PKN1_p \|PKN1	V(50) = K(50,1) * [PKN1_p] * [PKN1] -K(50,2) * [PKN1_p \|PKN1];
R51	PKN1_p \|PKN1	PKN1_p + PKN1_p	PKN1_p \|PKN1 → PKN1_p + PKN1_p	V(51) = K(51,1) * [PKN1_p \|PKN1];
R52	AKT1_p + CDKN1A	AKT1_p \|CDKN1A	AKT1_p + CDKN1A → AKT1_p \|CDKN1A	V(52) = K(52,1) * [AKT1_p] * [CDKN1A] -K(52,2) * [AKT1_p \|CDKN1A];
R53	AKT1_p \|CDKN1A	AKT1_p + CDKN1A_p	AKT1_p \|CDKN1A → AKT1_p + CDKN1A_p	V(53) = K(53,1) * [AKT1_p \|CDKN1A];
R54	AKT1 + SRC_p	SRC_p \|AKT1	AKT1 + SRC_p → SRC_p \|AKT1	V(54) = K(54,1) * [SRC_p] * [AKT1] -K(54,2) * [SRC_p \|AKT1];
R55	SRC_p \|AKT1	AKT1_p + SRC_p	SRC_p \|AKT1 → AKT1_p + SRC_p	V(55) = K(55,1) * [SRC_p \|AKT1];
R56	EIF2AK3 + JAK1_p	JAK1_p \|EIF2AK3	EIF2AK3 + JAK1_p → JAK1_p \|EIF2AK3	V(56) = K(56,1) * [JAK1_p] * [EIF2AK3] -K(56,2) * [JAK1_p \|EIF2AK3];
R57	JAK1_p \|EIF2AK3	EIF2AK3_p + JAK1_p	JAK1_p \|EIF2AK3 → EIF2AK3_p + JAK1_p	V(57) = K(57,1) * [JAK1_p \|EIF2AK3];
R58	MAPK1_p + SPHK1	MAPK1_p \|SPHK1	MAPK1_p + SPHK1 → MAPK1_p \|SPHK1	V(58) = K(58,1) * [MAPK1_p] * [SPHK1] -K(58,2) * [MAPK1_p \|SPHK1];
R59	MAPK1_p \|SPHK1	MAPK1_p + SPHK1_p	MAPK1_p \|SPHK1 → MAPK1_p + SPHK1_p	V(59) = K(59,1) * [MAPK1_p \|SPHK1];
R60	KIT + KIT_p	KIT_p \|KIT	KIT + KIT_p → KIT_p \|KIT	V(60) = K(60,1) * [KIT_p] * [KIT] -K(60,2) * [KIT_p \|KIT];
R61	KIT_p \|KIT	KIT_p + KIT_p	KIT_p \|KIT → KIT_p + KIT_p	V(61) = K(61,1) * [KIT_p \|KIT];
R62	MAPK1_p + RHOA	MAPK1_p \|RHOA	MAPK1_p + RHOA → MAPK1_p \|RHOA	V(62) = K(62,1) * [MAPK1_p] * [RHOA] -K(62,2) * [MAPK1_p \|RHOA];
R63	MAPK1_p \|RHOA	MAPK1_p + RHOA_p	MAPK1_p \|RHOA → MAPK1_p + RHOA_p	V(63) = K(63,1) * [MAPK1_p \|RHOA];
R64	EPOR + JAK2_p	JAK2_p \|EPOR	EPOR + JAK2_p → JAK2_p \|EPOR	V(64) = K(64,1) * [JAK2_p] * [EPOR] -K(64,2) * [JAK2_p \|EPOR];
R65	JAK2_p \|EPOR	EPOR_p + JAK2_p	JAK2_p \|EPOR → EPOR_p + JAK2_p	V(65) = K(65,1) * [JAK2_p \|EPOR];
R66	FOXO1 + MAPK1_p	MAPK1_p \|FOXO1	FOXO1 + MAPK1_p → MAPK1_p \|FOXO1	V(66) = K(66,1) * [MAPK1_p] * [FOXO1] -K(66,2) * [MAPK1_p \|FOXO1];
R67	MAPK1_p \|FOXO1	FOXO1_p + MAPK1_p	MAPK1_p \|FOXO1 → FOXO1_p + MAPK1_p	V(67) = K(67,1) * [MAPK1_p \|FOXO1];
R68	JAK2_p + STAT1	JAK2_p \|STAT1	JAK2_p + STAT1 → JAK2_p \|STAT1	V(68) = K(68,1) * [JAK2_p] * [STAT1] -K(68,2) * [JAK2_p \|STAT1];
R69	JAK2_p \|STAT1	JAK2_p + STAT1_p	JAK2_p \|STAT1 → JAK2_p + STAT1_p	V(69) = K(69,1) * [JAK2_p \|STAT1];
R70	EGFR + SRC_p	SRC_p \|EGFR	EGFR + SRC_p → SRC_p \|EGFR	V(70) = K(70,1) * [SRC_p] * [EGFR] -K(70,2) * [SRC_p \|EGFR];
R71	SRC_p \|EGFR	EGFR_p + SRC_p	SRC_p \|EGFR → EGFR_p + SRC_p	V(71) = K(71,1) * [SRC_p \|EGFR];
R72	SRC_p + STAT1	SRC_p \|STAT1	SRC_p + STAT1 → SRC_p \|STAT1	V(72) = K(72,1) * [SRC_p] * [STAT1] -K(72,2) * [SRC_p \|STAT1];
R73	SRC_p \|STAT1	SRC_p + STAT1_p	SRC_p \|STAT1 → SRC_p + STAT1_p	V(73) = K(73,1) * [SRC_p \|STAT1];
R74	MAPK1_p + SMAD3	MAPK1_p \|SMAD3	MAPK1_p + SMAD3 → MAPK1_p \|SMAD3	V(74) = K(74,1) * [MAPK1_p] * [SMAD3] -K(74,2) * [MAPK1_p \|SMAD3];
R75	MAPK1_p \|SMAD3	MAPK1_p + SMAD3_p	MAPK1_p \|SMAD3 → MAPK1_p + SMAD3_p	V(75) = K(75,1) * [MAPK1_p \|SMAD3];
R76	ERN1 + ERN1_p	ERN1_p \|ERN1	ERN1 + ERN1_p → ERN1_p \|ERN1	V(76) = K(76,1) * [ERN1_p] * [ERN1] -K(76,2) * [ERN1_p \|ERN1];
R77	ERN1_p \|ERN1	ERN1_p + ERN1_p	ERN1_p \|ERN1 → ERN1_p + ERN1_p	V(77) = K(77,1) * [ERN1_p \|ERN1];
R78	DEPTOR + RPS6KA3_p	RPS6KA3_p \|DEPTOR	DEPTOR + RPS6KA3_p → RPS6KA3_p \|DEPTOR	V(78) = K(78,1) * [RPS6KA3_p] * [DEPTOR] -K(78,2) * [RPS6KA3_p \|DEPTOR];
R79	RPS6KA3_p \|DEPTOR	DEPTOR_p + RPS6KA3_p	RPS6KA3_p \|DEPTOR → DEPTOR_p + RPS6KA3_p	V(79) = K(79,1) * [RPS6KA3_p \|DEPTOR];
R80	MAP3K5 + RPS6KA3_p	RPS6KA3_p \|MAP3K5	MAP3K5 + RPS6KA3_p → RPS6KA3_p \|MAP3K5	V(80) = K(80,1) * [RPS6KA3_p] * [MAP3K5] -K(80,2) * [RPS6KA3_p \|MAP3K5];
R81	RPS6KA3_p \|MAP3K5	MAP3K5_p + RPS6KA3_p	RPS6KA3_p \|MAP3K5 → MAP3K5_p + RPS6KA3_p	V(81) = K(81,1) * [RPS6KA3_p \|MAP3K5];
R82	AKT1_p + CDKN1B	AKT1_p \|CDKN1B	AKT1_p + CDKN1B → AKT1_p \|CDKN1B	V(82) = K(82,1) * [AKT1_p] * [CDKN1B] -K(82,2) * [AKT1_p \|CDKN1B];
R83	AKT1_p \|CDKN1B	AKT1_p + CDKN1B_p	AKT1_p \|CDKN1B → AKT1_p + CDKN1B_p	V(83) = K(83,1) * [AKT1_p \|CDKN1B];
R84	IGF1R + SRC_p	SRC_p \|IGF1R	IGF1R + SRC_p → SRC_p \|IGF1R	V(84) = K(84,1) * [SRC_p] * [IGF1R] -K(84,2) * [SRC_p \|IGF1R];
R85	SRC_p \|IGF1R	IGF1R_p + SRC_p	SRC_p \|IGF1R → IGF1R_p + SRC_p	V(85) = K(85,1) * [SRC_p \|IGF1R];
R86	MAPK1_p + SIGNOR-C154	MAPK1_p \|SIGNOR-C154	MAPK1_p + SIGNOR-C154 → MAPK1_p \|SIGNOR-C154	V(86) = K(86,1) * [MAPK1_p] * [SIGNOR-C154] -K(86,2) * [MAPK1_p \|SIGNOR-C154];
R87	MAPK1_p \|SIGNOR-C154	MAPK1_p + SIGNOR-C154_p	MAPK1_p \|SIGNOR-C154 → MAPK1_p + SIGNOR-C154_p	V(87) = K(87,1) * [MAPK1_p \|SIGNOR-C154];
R88	IGF1R + IGF1R_p	IGF1R_p \|IGF1R	IGF1R + IGF1R_p → IGF1R_p \|IGF1R	V(88) = K(88,1) * [IGF1R_p] * [IGF1R] -K(88,2) * [IGF1R_p \|IGF1R];
R89	IGF1R_p \|IGF1R	IGF1R_p + IGF1R_p	IGF1R_p \|IGF1R → IGF1R_p + IGF1R_p	V(89) = K(89,1) * [IGF1R_p \|IGF1R];
R90	FOXO1 + SGK1	SGK1 \|FOXO1	FOXO1 + SGK1 → SGK1 \|FOXO1	V(90) = K(90,1) * [SGK1] * [FOXO1] -K(90,2) * [SGK1 \|FOXO1];
R91	SGK1 \|FOXO1	FOXO1_p + SGK1	SGK1 \|FOXO1 → FOXO1_p + SGK1	V(91) = K(91,1) * [SGK1 \|FOXO1];
R92	CDKN1B + SGK1	SGK1 \|CDKN1B	CDKN1B + SGK1 → SGK1 \|CDKN1B	V(92) = K(92,1) * [SGK1] * [CDKN1B] -K(92,2) * [SGK1 \|CDKN1B];
R93	SGK1 \|CDKN1B	CDKN1B_p + SGK1	SGK1 \|CDKN1B → CDKN1B_p + SGK1	V(93) = K(93,1) * [SGK1 \|CDKN1B];
R94	CREB1 + RPS6KA3_p	RPS6KA3_p \|CREB1	CREB1 + RPS6KA3_p → RPS6KA3_p \|CREB1	V(94) = K(94,1) * [RPS6KA3_p] * [CREB1] -K(94,2) * [RPS6KA3_p \|CREB1];
R95	RPS6KA3_p \|CREB1	CREB1_p + RPS6KA3_p	RPS6KA3_p \|CREB1 → CREB1_p + RPS6KA3_p	V(95) = K(95,1) * [RPS6KA3_p \|CREB1];
R96	EGFR + MAPK1_p	MAPK1_p \|EGFR	EGFR + MAPK1_p → MAPK1_p \|EGFR	V(96) = K(96,1) * [MAPK1_p] * [EGFR] -K(96,2) * [MAPK1_p \|EGFR];
R97	MAPK1_p \|EGFR	EGFR_p + MAPK1_p	MAPK1_p \|EGFR → EGFR_p + MAPK1_p	V(97) = K(97,1) * [MAPK1_p \|EGFR];
R98	PTEN + SRC_p	SRC_p \|PTEN	PTEN + SRC_p → SRC_p \|PTEN	V(98) = K(98,1) * [SRC_p] * [PTEN] -K(98,2) * [SRC_p \|PTEN];
R99	SRC_p \|PTEN	PTEN_p + SRC_p	SRC_p \|PTEN → PTEN_p + SRC_p	V(99) = K(99,1) * [SRC_p \|PTEN];
R100	EIF2AK3 + EIF2AK3_p	EIF2AK3_p \|EIF2AK3	EIF2AK3 + EIF2AK3_p → EIF2AK3_p \|EIF2AK3	V(100) = K(100,1) * [EIF2AK3_p] * [EIF2AK3] -K(100,2) * [EIF2AK3_p \|EIF2AK3];
R101	EIF2AK3_p \|EIF2AK3	EIF2AK3_p + EIF2AK3_p	EIF2AK3_p \|EIF2AK3 → EIF2AK3_p + EIF2AK3_p	V(101) = K(101,1) * [EIF2AK3_p \|EIF2AK3];
R102	MAP3K5 + MAP3K5_p	MAP3K5_p \|MAP3K5	MAP3K5 + MAP3K5_p → MAP3K5_p \|MAP3K5	V(102) = K(102,1) * [MAP3K5_p] * [MAP3K5] -K(102,2) * [MAP3K5_p \|MAP3K5];
R103	MAP3K5_p \|MAP3K5	MAP3K5_p + MAP3K5_p	MAP3K5_p \|MAP3K5 → MAP3K5_p + MAP3K5_p	V(103) = K(103,1) * [MAP3K5_p \|MAP3K5];
R104	AKT1_p + VIM	AKT1_p \|VIM	AKT1_p + VIM → AKT1_p \|VIM	V(104) = K(104,1) * [AKT1_p] * [VIM] -K(104,2) * [AKT1_p \|VIM];
R105	AKT1_p \|VIM	AKT1_p + VIM_p	AKT1_p \|VIM → AKT1_p + VIM_p	V(105) = K(105,1) * [AKT1_p \|VIM];
R106	AKT1 + ILK_p	ILK_p \|AKT1	AKT1 + ILK_p → ILK_p \|AKT1	V(106) = K(106,1) * [ILK_p] * [AKT1] -K(106,2) * [ILK_p \|AKT1];
R107	ILK_p \|AKT1	AKT1_p + ILK_p	ILK_p \|AKT1 → AKT1_p + ILK_p	V(107) = K(107,1) * [ILK_p \|AKT1];
R108	MAPK1_p + SP1	MAPK1_p \|SP1	MAPK1_p + SP1 → MAPK1_p \|SP1	V(108) = K(108,1) * [MAPK1_p] * [SP1] -K(108,2) * [MAPK1_p \|SP1];
R109	MAPK1_p \|SP1	MAPK1_p + SP1_p	MAPK1_p \|SP1 → MAPK1_p + SP1_p	V(109) = K(109,1) * [MAPK1_p \|SP1];
R110	PTEN + ROCK1	ROCK1 \|PTEN	PTEN + ROCK1 → ROCK1 \|PTEN	V(110) = K(110,1) * [ROCK1] * [PTEN] -K(110,2) * [ROCK1 \|PTEN];
R111	ROCK1 \|PTEN	PTEN_p + ROCK1	ROCK1 \|PTEN → PTEN_p + ROCK1	V(111) = K(111,1) * [ROCK1 \|PTEN];
R112	CDKN1A + MAPK1_p	MAPK1_p \|CDKN1A	CDKN1A + MAPK1_p → MAPK1_p \|CDKN1A	V(112) = K(112,1) * [MAPK1_p] * [CDKN1A] -K(112,2) * [MAPK1_p \|CDKN1A];
R113	MAPK1_p \|CDKN1A	CDKN1A_p + MAPK1_p	MAPK1_p \|CDKN1A → CDKN1A_p + MAPK1_p	V(113) = K(113,1) * [MAPK1_p \|CDKN1A];
R114	FOXO1 + PRKAA1	PRKAA1 \|FOXO1	FOXO1 + PRKAA1 → PRKAA1 \|FOXO1	V(114) = K(114,1) * [PRKAA1] * [FOXO1] -K(114,2) * [PRKAA1 \|FOXO1];
R115	PRKAA1 \|FOXO1	FOXO1_p + PRKAA1	PRKAA1 \|FOXO1 → FOXO1_p + PRKAA1	V(115) = K(115,1) * [PRKAA1 \|FOXO1];
R116	JAK2 + MAPK1_p	MAPK1_p \|JAK2	JAK2 + MAPK1_p → MAPK1_p \|JAK2	V(116) = K(116,1) * [MAPK1_p] * [JAK2] -K(116,2) * [MAPK1_p \|JAK2];
R117	MAPK1_p \|JAK2	JAK2_p + MAPK1_p	MAPK1_p \|JAK2 → JAK2_p + MAPK1_p	V(117) = K(117,1) * [MAPK1_p \|JAK2];
R118	IGF1R_p + PCNA	IGF1R_p \|PCNA	IGF1R_p + PCNA → IGF1R_p \|PCNA	V(118) = K(118,1) * [IGF1R_p] * [PCNA] -K(118,2) * [IGF1R_p \|PCNA];
R119	IGF1R_p \|PCNA	IGF1R_p + PCNA_p	IGF1R_p \|PCNA → IGF1R_p + PCNA_p	V(119) = K(119,1) * [IGF1R_p \|PCNA];
R120	AKT1_p + CASP9	AKT1_p \|CASP9	AKT1_p + CASP9 → AKT1_p \|CASP9	V(120) = K(120,1) * [AKT1_p] * [CASP9] -K(120,2) * [AKT1_p \|CASP9];
R121	AKT1_p \|CASP9	AKT1_p + CASP9_p	AKT1_p \|CASP9 → AKT1_p + CASP9_p	V(121) = K(121,1) * [AKT1_p \|CASP9];
R122	AKT1_p + NR3C1	AKT1_p \|NR3C1	AKT1_p + NR3C1 → AKT1_p \|NR3C1	V(122) = K(122,1) * [AKT1_p] * [NR3C1] -K(122,2) * [AKT1_p \|NR3C1];
R123	AKT1_p \|NR3C1	AKT1_p + NR3C1_p	AKT1_p \|NR3C1 → AKT1_p + NR3C1_p	V(123) = K(123,1) * [AKT1_p \|NR3C1];
R124	CLTC + SRC_p	SRC_p \|CLTC	CLTC + SRC_p → SRC_p \|CLTC	V(124) = K(124,1) * [SRC_p] * [CLTC] -K(124,2) * [SRC_p \|CLTC];
R125	SRC_p \|CLTC	CLTC_p + SRC_p	SRC_p \|CLTC → CLTC_p + SRC_p	V(125) = K(125,1) * [SRC_p \|CLTC];
R126	JAK2_p + STAT6	JAK2_p \|STAT6	JAK2_p + STAT6 → JAK2_p \|STAT6	V(126) = K(126,1) * [JAK2_p] * [STAT6] -K(126,2) * [JAK2_p \|STAT6];
R127	JAK2_p \|STAT6	JAK2_p + STAT6_p	JAK2_p \|STAT6 → JAK2_p + STAT6_p	V(127) = K(127,1) * [JAK2_p \|STAT6];
R128	MAP3K14_p + NFKB2	MAP3K14_p \|NFKB2	MAP3K14_p + NFKB2 → MAP3K14_p \|NFKB2	V(128) = K(128,1) * [MAP3K14_p] * [NFKB2] -K(128,2) * [MAP3K14_p \|NFKB2];
R129	MAP3K14_p \|NFKB2	MAP3K14_p + NFKB2_p	MAP3K14_p \|NFKB2 → MAP3K14_p + NFKB2_p	V(129) = K(129,1) * [MAP3K14_p \|NFKB2];
R130	FOXO1 + PKN1_p	PKN1_p \|FOXO1	FOXO1 + PKN1_p → PKN1_p \|FOXO1	V(130) = K(130,1) * [PKN1_p] * [FOXO1] -K(130,2) * [PKN1_p \|FOXO1];
R131	PKN1_p \|FOXO1	FOXO1_p + PKN1_p	PKN1_p \|FOXO1 → FOXO1_p + PKN1_p	V(131) = K(131,1) * [PKN1_p \|FOXO1];
R132	CASP9 + MAPK1_p	MAPK1_p \|CASP9	CASP9 + MAPK1_p → MAPK1_p \|CASP9	V(132) = K(132,1) * [MAPK1_p] * [CASP9] -K(132,2) * [MAPK1_p \|CASP9];
R133	MAPK1_p \|CASP9	CASP9_p + MAPK1_p	MAPK1_p \|CASP9 → CASP9_p + MAPK1_p	V(133) = K(133,1) * [MAPK1_p \|CASP9];
R134	MAP3K14 + MAP3K14_p	MAP3K14_p \|MAP3K14	MAP3K14 + MAP3K14_p → MAP3K14_p \|MAP3K14	V(134) = K(134,1) * [MAP3K14_p] * [MAP3K14] -K(134,2) * [MAP3K14_p \|MAP3K14];
R135	MAP3K14_p \|MAP3K14	MAP3K14_p + MAP3K14_p	MAP3K14_p \|MAP3K14 → MAP3K14_p + MAP3K14_p	V(135) = K(135,1) * [MAP3K14_p \|MAP3K14];
R136	JAK1_p + STAT6	JAK1_p \|STAT6	JAK1_p + STAT6 → JAK1_p \|STAT6	V(136) = K(136,1) * [JAK1_p] * [STAT6] -K(136,2) * [JAK1_p \|STAT6];
R137	JAK1_p \|STAT6	JAK1_p + STAT6_p	JAK1_p \|STAT6 → JAK1_p + STAT6_p	V(137) = K(137,1) * [JAK1_p \|STAT6];
R138	AKT1_p + YAP1	AKT1_p \|YAP1	AKT1_p + YAP1 → AKT1_p \|YAP1	V(138) = K(138,1) * [AKT1_p] * [YAP1] -K(138,2) * [AKT1_p \|YAP1];
R139	AKT1_p \|YAP1	AKT1_p + YAP1_p	AKT1_p \|YAP1 → AKT1_p + YAP1_p	V(139) = K(139,1) * [AKT1_p \|YAP1];
R140	CDKN1B + JAK2_p	JAK2_p \|CDKN1B	CDKN1B + JAK2_p → JAK2_p \|CDKN1B	V(140) = K(140,1) * [JAK2_p] * [CDKN1B] -K(140,2) * [JAK2_p \|CDKN1B];
R141	JAK2_p \|CDKN1B	CDKN1B_p + JAK2_p	JAK2_p \|CDKN1B → CDKN1B_p + JAK2_p	V(141) = K(141,1) * [JAK2_p \|CDKN1B];
R142	SMAD1 + SMAD4	SMAD1 \|SMAD4	SMAD1 + SMAD4 → SMAD1 \|SMAD4	V(142) = K(142,1) * [SMAD1] * [SMAD4] -K(142,2) * [SMAD1 \|SMAD4];
R143	SMAD1 \|SMAD4	SMAD1 + SMAD4_p	SMAD1 \|SMAD4 → SMAD1 + SMAD4_p	V(143) = K(143,1) * [SMAD1 \|SMAD4];
R144	FOS + RPS6KA3_p	RPS6KA3_p \|FOS	FOS + RPS6KA3_p → RPS6KA3_p \|FOS	V(144) = K(144,1) * [RPS6KA3_p] * [FOS] -K(144,2) * [RPS6KA3_p \|FOS];
R145	RPS6KA3_p \|FOS	FOS_p + RPS6KA3_p	RPS6KA3_p \|FOS → FOS_p + RPS6KA3_p	V(145) = K(145,1) * [RPS6KA3_p \|FOS];
R146	AKT1_p + RPS6KA3	AKT1_p \|RPS6KA3	AKT1_p + RPS6KA3 → AKT1_p \|RPS6KA3	V(146) = K(146,1) * [AKT1_p] * [RPS6KA3] -K(146,2) * [AKT1_p \|RPS6KA3];
R147	AKT1_p \|RPS6KA3	AKT1_p + RPS6KA3_p	AKT1_p \|RPS6KA3 → AKT1_p + RPS6KA3_p	V(147) = K(147,1) * [AKT1_p \|RPS6KA3];
R148	KIT_p + STAT1	KIT_p \|STAT1	KIT_p + STAT1 → KIT_p \|STAT1	V(148) = K(148,1) * [KIT_p] * [STAT1] -K(148,2) * [KIT_p \|STAT1];
R149	KIT_p \|STAT1	KIT_p + STAT1_p	KIT_p \|STAT1 → KIT_p + STAT1_p	V(149) = K(149,1) * [KIT_p \|STAT1];
R150	RPS6KA3 + RPS6KA3_p	RPS6KA3_p \|RPS6KA3	RPS6KA3 + RPS6KA3_p → RPS6KA3_p \|RPS6KA3	V(150) = K(150,1) * [RPS6KA3_p] * [RPS6KA3] -K(150,2) * [RPS6KA3_p \|RPS6KA3];
R151	RPS6KA3_p \|RPS6KA3	RPS6KA3_p + RPS6KA3_p	RPS6KA3_p \|RPS6KA3 → RPS6KA3_p + RPS6KA3_p	V(151) = K(151,1) * [RPS6KA3_p \|RPS6KA3];
R152	AKT1_p + CTNNB1	AKT1_p \|CTNNB1	AKT1_p + CTNNB1 → AKT1_p \|CTNNB1	V(152) = K(152,1) * [AKT1_p] * [CTNNB1] -K(152,2) * [AKT1_p \|CTNNB1];
R153	AKT1_p \|CTNNB1	AKT1_p + CTNNB1_p	AKT1_p \|CTNNB1 → AKT1_p + CTNNB1_p	V(153) = K(153,1) * [AKT1_p \|CTNNB1];
R154	NR4A1 + RPS6KA3_p	RPS6KA3_p \|NR4A1	NR4A1 + RPS6KA3_p → RPS6KA3_p \|NR4A1	V(154) = K(154,1) * [RPS6KA3_p] * [NR4A1] -K(154,2) * [RPS6KA3_p \|NR4A1];
R155	RPS6KA3_p \|NR4A1	NR4A1_p + RPS6KA3_p	RPS6KA3_p \|NR4A1 → NR4A1_p + RPS6KA3_p	V(155) = K(155,1) * [RPS6KA3_p \|NR4A1];
R156	ROCK1 + TP53	ROCK1 \|TP53	ROCK1 + TP53 → ROCK1 \|TP53	V(156) = K(156,1) * [ROCK1] * [TP53] -K(156,2) * [ROCK1 \|TP53];
R157	ROCK1 \|TP53	ROCK1 + TP53_p	ROCK1 \|TP53 → ROCK1 + TP53_p	V(157) = K(157,1) * [ROCK1 \|TP53];
R158	AKT1_p + RUNX2	AKT1_p \|RUNX2	AKT1_p + RUNX2 → AKT1_p \|RUNX2	V(158) = K(158,1) * [AKT1_p] * [RUNX2] -K(158,2) * [AKT1_p \|RUNX2];
R159	AKT1_p \|RUNX2	AKT1_p + RUNX2_p	AKT1_p \|RUNX2 → AKT1_p + RUNX2_p	V(159) = K(159,1) * [AKT1_p \|RUNX2];
R160	MAPK1 + MAPK1_p	MAPK1_p \|MAPK1	MAPK1 + MAPK1_p → MAPK1_p \|MAPK1	V(160) = K(160,1) * [MAPK1_p] * [MAPK1] -K(160,2) * [MAPK1_p \|MAPK1];
R161	MAPK1_p \|MAPK1	MAPK1_p + MAPK1_p	MAPK1_p \|MAPK1 → MAPK1_p + MAPK1_p	V(161) = K(161,1) * [MAPK1_p \|MAPK1];
R162	MAPK1_p + RRAS	MAPK1_p \|RRAS	MAPK1_p + RRAS → MAPK1_p \|RRAS	V(162) = K(162,1) * [MAPK1_p] * [RRAS] -K(162,2) * [MAPK1_p \|RRAS];
R163	MAPK1_p \|RRAS	MAPK1_p + RRAS_p	MAPK1_p \|RRAS → MAPK1_p + RRAS_p	V(163) = K(163,1) * [MAPK1_p \|RRAS];
R164	CDH1 + SRC_p	SRC_p \|CDH1	CDH1 + SRC_p → SRC_p \|CDH1	V(164) = K(164,1) * [SRC_p] * [CDH1] -K(164,2) * [SRC_p \|CDH1];
R165	SRC_p \|CDH1	CDH1_p + SRC_p	SRC_p \|CDH1 → CDH1_p + SRC_p	V(165) = K(165,1) * [SRC_p \|CDH1];
R166	MAPK1_p + ZFP36	MAPK1_p \|ZFP36	MAPK1_p + ZFP36 → MAPK1_p \|ZFP36	V(166) = K(166,1) * [MAPK1_p] * [ZFP36] -K(166,2) * [MAPK1_p \|ZFP36];
R167	MAPK1_p \|ZFP36	MAPK1_p + ZFP36_p	MAPK1_p \|ZFP36 → MAPK1_p + ZFP36_p	V(167) = K(167,1) * [MAPK1_p \|ZFP36];
R168	MAPK1_p + RCAN1	MAPK1_p \|RCAN1	MAPK1_p + RCAN1 → MAPK1_p \|RCAN1	V(168) = K(168,1) * [MAPK1_p] * [RCAN1] -K(168,2) * [MAPK1_p \|RCAN1];
R169	MAPK1_p \|RCAN1	MAPK1_p + RCAN1_p	MAPK1_p \|RCAN1 → MAPK1_p + RCAN1_p	V(169) = K(169,1) * [MAPK1_p \|RCAN1];
R170	EGFR + JAK2_p	JAK2_p \|EGFR	EGFR + JAK2_p → JAK2_p \|EGFR	V(170) = K(170,1) * [JAK2_p] * [EGFR] -K(170,2) * [JAK2_p \|EGFR];
R171	JAK2_p \|EGFR	EGFR_p + JAK2_p	JAK2_p \|EGFR → EGFR_p + JAK2_p	V(171) = K(171,1) * [JAK2_p \|EGFR];
R172	EGFR + PKN1_p	PKN1_p \|EGFR	EGFR + PKN1_p → PKN1_p \|EGFR	V(172) = K(172,1) * [PKN1_p] * [EGFR] -K(172,2) * [PKN1_p \|EGFR];
R173	PKN1_p \|EGFR	EGFR_p + PKN1_p	PKN1_p \|EGFR → EGFR_p + PKN1_p	V(173) = K(173,1) * [PKN1_p \|EGFR];
R174	AKT1_p + MAP3K5	AKT1_p \|MAP3K5	AKT1_p + MAP3K5 → AKT1_p \|MAP3K5	V(174) = K(174,1) * [AKT1_p] * [MAP3K5] -K(174,2) * [AKT1_p \|MAP3K5];
R175	AKT1_p \|MAP3K5	AKT1_p + MAP3K5_p	AKT1_p \|MAP3K5 → AKT1_p + MAP3K5_p	V(175) = K(175,1) * [AKT1_p \|MAP3K5];
R176	AKT1_p + PARK7	AKT1_p \|PARK7	AKT1_p + PARK7 → AKT1_p \|PARK7	V(176) = K(176,1) * [AKT1_p] * [PARK7] -K(176,2) * [AKT1_p \|PARK7];
R177	AKT1_p \|PARK7	AKT1_p + PARK7_p	AKT1_p \|PARK7 → AKT1_p + PARK7_p	V(177) = K(177,1) * [AKT1_p \|PARK7];
R178	KIT + SRC_p	SRC_p \|KIT	KIT + SRC_p → SRC_p \|KIT	V(178) = K(178,1) * [SRC_p] * [KIT] -K(178,2) * [SRC_p \|KIT];
R179	SRC_p \|KIT	KIT_p + SRC_p	SRC_p \|KIT → KIT_p + SRC_p	V(179) = K(179,1) * [SRC_p \|KIT];
R180	SGK1 + SP1	SGK1 \|SP1	SGK1 + SP1 → SGK1 \|SP1	V(180) = K(180,1) * [SGK1] * [SP1] -K(180,2) * [SGK1 \|SP1];
R181	SGK1 \|SP1	SGK1 + SP1_p	SGK1 \|SP1 → SGK1 + SP1_p	V(181) = K(181,1) * [SGK1 \|SP1];
R182	PROM1 + SRC_p	SRC_p \|PROM1	PROM1 + SRC_p → SRC_p \|PROM1	V(182) = K(182,1) * [SRC_p] * [PROM1] -K(182,2) * [SRC_p \|PROM1];
R183	SRC_p \|PROM1	PROM1_p + SRC_p	SRC_p \|PROM1 → PROM1_p + SRC_p	V(183) = K(183,1) * [SRC_p \|PROM1];
R184	CTNNB1 + SRC_p	SRC_p \|CTNNB1	CTNNB1 + SRC_p → SRC_p \|CTNNB1	V(184) = K(184,1) * [SRC_p] * [CTNNB1] -K(184,2) * [SRC_p \|CTNNB1];
R185	SRC_p \|CTNNB1	CTNNB1_p + SRC_p	SRC_p \|CTNNB1 → CTNNB1_p + SRC_p	V(185) = K(185,1) * [SRC_p \|CTNNB1];
R186	MAPK1 + SGK1	SGK1 \|MAPK1	MAPK1 + SGK1 → SGK1 \|MAPK1	V(186) = K(186,1) * [SGK1] * [MAPK1] -K(186,2) * [SGK1 \|MAPK1];
R187	SGK1 \|MAPK1	MAPK1_p + SGK1	SGK1 \|MAPK1 → MAPK1_p + SGK1	V(187) = K(187,1) * [SGK1 \|MAPK1];
R188	GHR + JAK2_p	JAK2_p \|GHR	GHR + JAK2_p → JAK2_p \|GHR	V(188) = K(188,1) * [JAK2_p] * [GHR] -K(188,2) * [JAK2_p \|GHR];
R189	JAK2_p \|GHR	GHR_p + JAK2_p	JAK2_p \|GHR → GHR_p + JAK2_p	V(189) = K(189,1) * [JAK2_p \|GHR];
R190	DDIT3 + PRKAA1	PRKAA1 \|DDIT3	DDIT3 + PRKAA1 → PRKAA1 \|DDIT3	V(190) = K(190,1) * [PRKAA1] * [DDIT3] -K(190,2) * [PRKAA1 \|DDIT3];
R191	PRKAA1 \|DDIT3	DDIT3_p + PRKAA1	PRKAA1 \|DDIT3 → DDIT3_p + PRKAA1	V(191) = K(191,1) * [PRKAA1 \|DDIT3];
R192	RPS6KA3_p + TP53	RPS6KA3_p \|TP53	RPS6KA3_p + TP53 → RPS6KA3_p \|TP53	V(192) = K(192,1) * [RPS6KA3_p] * [TP53] -K(192,2) * [RPS6KA3_p \|TP53];
R193	RPS6KA3_p \|TP53	RPS6KA3_p + TP53_p	RPS6KA3_p \|TP53 → RPS6KA3_p + TP53_p	V(193) = K(193,1) * [RPS6KA3_p \|TP53];
R194	MYD88 + SRC_p	SRC_p \|MYD88	MYD88 + SRC_p → SRC_p \|MYD88	V(194) = K(194,1) * [SRC_p] * [MYD88] -K(194,2) * [SRC_p \|MYD88];
R195	SRC_p \|MYD88	MYD88_p + SRC_p	SRC_p \|MYD88 → MYD88_p + SRC_p	V(195) = K(195,1) * [SRC_p \|MYD88];
R196	MAPK1_p + XBP1	MAPK1_p \|XBP1	MAPK1_p + XBP1 → MAPK1_p \|XBP1	V(196) = K(196,1) * [MAPK1_p] * [XBP1] -K(196,2) * [MAPK1_p \|XBP1];
R197	MAPK1_p \|XBP1	MAPK1_p + XBP1_p	MAPK1_p \|XBP1 → MAPK1_p + XBP1_p	V(197) = K(197,1) * [MAPK1_p \|XBP1];
R198	NR3C1 + SGK1	SGK1 \|NR3C1	NR3C1 + SGK1 → SGK1 \|NR3C1	V(198) = K(198,1) * [SGK1] * [NR3C1] -K(198,2) * [SGK1 \|NR3C1];
R199	SGK1 \|NR3C1	NR3C1_p + SGK1	SGK1 \|NR3C1 → NR3C1_p + SGK1	V(199) = K(199,1) * [SGK1 \|NR3C1];