Selected Cell
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Value:
TAL_interactions
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| ENTITYA | ENTITYB | EFFECT | MECHANISM | TAX_ID | PMID | ||||
| AKT1 | FOXO1 | down-regulates | phosphorylation | 9606 | 11237865 | ||||
| PKN1 | FOXO1 | down-regulates | phosphorylation | 9606 | 12560069 | ||||
| PTPN6 | STAT6 | down-regulates | 9606 | 9852037 | |||||
| PTPN6 | INSR | down-regulates | dephosphorylation | 9606 | 10734133 | ||||
| PTPN6 | STAT3 | down-regulates | dephosphorylation | 9606 | 18508557 | ||||
| PTPN6 | INSR | down-regulates | dephosphorylation | 9606 | 10734133 | ||||
| IKBKB | CDKN2A | down-regulates | phosphorylation | 9606 | 20152798 | ||||
| DUSP1 | MAPK8 | down-regulates | dephosphorylation | 9606 | 9020184 | ||||
| PTPN6 | INSR | down-regulates | dephosphorylation | 9606 | 10734133 | ||||
| INSR | CALM1 | down-regulates | phosphorylation | 9606 | 3415247 | ||||
| AKT1 | FAS | down-regulates | 9606 | 15004527 | |||||
| JAK2 | JAK2 | down-regulates | phosphorylation | 9606 | 19364823 | ||||
| PTEN | STAT5A | down-regulates | dephosphorylation | 9606 | 20596030 | ||||
| JAK2 | EZH2 | down-regulates | phosphorylation | 9606 | 24469040 | ||||
| MAPK8 | STAT6 | down-regulates | phosphorylation | 9606 | 21123173 | ||||
| PTPN6 | INSR | down-regulates | dephosphorylation | 9606 | 10734133 | ||||
| AKT1 | HSPB1 | down-regulates | phosphorylation | 9606 | 19593530 | ||||
| PTPN6 | JAK1 | down-regulates | dephosphorylation | 9606 | 14624462 | ||||
| AKT1 | FOXO1 | down-regulates | phosphorylation | 9606 | 21798082 | ||||
| STAT6 | STAT1 | down-regulates | binding | 9606 | 10982806 | ||||
| JAK2 | JAK2 | down-regulates | phosphorylation | 9606 | 21841788 | ||||
| AKT1 | EZH2 | down-regulates | phosphorylation | 9606 | 16224021 | ||||
| IKBKB | IKBKB | down-regulates | phosphorylation | 9606 | 10195894 | ||||
| PTEN | AKT1 | down-regulates | 9606 | 19903340 | |||||
| IKBKB | IKBKB | down-regulates | phosphorylation | 9606 | 10195894 | ||||
| IKBKB | IKBKB | down-regulates | phosphorylation | 9606 | 10195894 | ||||
| IKBKB | IKBKB | down-regulates | phosphorylation | 9606 | 10195894 | ||||
| JAK2 | JAK2 | down-regulates | phosphorylation | 9606 | 15143187 | ||||
| AKT1 | BAX | down-regulates | phosphorylation | 9606 | 14766748 | ||||
| PINK1 | PTEN | down-regulates | phosphorylation | 9606 | 37940999 | ||||
| IKBKB | IKBKB | down-regulates | phosphorylation | 9606 | 10195894 | ||||
| PTEN | AKT1 | down-regulates | 9606 | 20596030 | |||||
| IKBKB | IKBKB | down-regulates | phosphorylation | 9606 | 10195894 | ||||
| IKBKB | IKBKB | down-regulates | phosphorylation | 9606 | 10195894 | ||||
| IKBKB | IKBKB | down-regulates | phosphorylation | 9606 | 10195894 | ||||
| JAK2 | JAK2 | down-regulates | phosphorylation | 9606 | 21841788 | ||||
| IKBKB | IKBKB | down-regulates | phosphorylation | 9606 | 10195894 | ||||
| FOXO1 | STAT3 | down-regulates | binding | 9606 | 25510553 | ||||
| DUSP1 | JUN | down-regulates | dephosphorylation | 9606 | 26734995 | ||||
| FBN1 | FBLN5 | down-regulates | binding | 9606 | 19570982 | ||||
| FBP1 | HIF1A | down-regulates | binding | 9606 | 30616754 | ||||
| IKBKB | IKBKB | down-regulates | phosphorylation | 9606 | 10195894 | ||||
| IKBKB | IKBKB | down-regulates | phosphorylation | 9606 | 10195894 | ||||
| IKBKB | IKBKB | down-regulates | phosphorylation | 9606 | 10195894 | ||||
| AKT1 | AKT1S1 | down-regulates | phosphorylation | 9606 | 12524439 | ||||
| TRIB3 | AKT1 | down-regulates | binding | 9606 | 12791994 | ||||
| IKBKB | IKBKB | down-regulates | phosphorylation | 9606 | 10195894 | ||||
| IKBKB | IKBKB | down-regulates | phosphorylation | 9606 | 10195894 | ||||
| PTEN | SP1 | down-regulates | dephosphorylation | 9606 | 21603612 | ||||
| PINK1 | MFN1 | down-regulates | ubiquitination | 9606 | 20871098 | ||||
| MAPK8 | MFN2 | down-regulates | phosphorylation | 9606 | 22748923 | ||||
| PINK1 | MFN2 | down-regulates | ubiquitination | 9606 | 20871098 | ||||
| CLU | IKBKB | down-regulates | binding | 9606 | 20068069 | ||||
| PTPN6 | CTNNB1 | down-regulates | dephosphorylation | 9606 | 20840866 | ||||
| PTPN6 | CTNNB1 | down-regulates | dephosphorylation | 9606 | 20840866 | ||||
| AKT1 | FOXO1 | down-regulates | phosphorylation | 9606 | 21440011 | ||||
| EGR1 | FAS | down-regulates | transcriptional regulation | 9606 | 9300687 | ||||
| TP53 | SLC2A1 | down-regulates | transcriptional regulation | 9606 | 27692180 | ||||
| F2RL1 | TXNIP | down-regulates | transcriptional regulation | 9606 | 21072196 | ||||
| MECP2 | CCND1 | down-regulates | transcriptional regulation | 9606 | 15870696 | ||||
| F2RL1 | CTSD | down-regulates | transcriptional regulation | 9606 | 21072196 | ||||
| SIRT2 | CDKN1A | down-regulates | transcriptional regulation | 9606 | 14522900 | ||||
| PDPK1 | PDPK1 | unknown | phosphorylation | 9606 | 10455013 | ||||
| PDPK1 | PDPK1 | unknown | phosphorylation | 9606 | 10455013 | ||||
| PDPK1 | PDPK1 | unknown | phosphorylation | 9606 | 10455013 | ||||
| PDPK1 | PDPK1 | unknown | phosphorylation | 9606 | 10455013 | ||||
| TGFBR1 | PIK3R1 | up-regulates | binding | 9606 | 9435577 | ||||
| IGF1R | IRS2 | up-regulates | phosphorylation | 9606 | 10471495 | ||||
| PDPK1 | AKT1 | up-regulates | phosphorylation | 9606 | 21798082 | ||||
| INSR | PTPN6 | up-regulates | phosphorylation | 9606 | 7512963 | ||||
| TGFB2 | TGFBR1 | up-regulates | binding | 9606 | 22326956 | ||||
| STAT3 | TGFB1 | up-regulates | transcriptional regulation | 9606 | 22378047 | ||||
| IGF1R | IGF1R | up-regulates | phosphorylation | 9606 | 7493944 | ||||
| MAPK8 | SP1 | up-regulates | phosphorylation | 9606 | 19245816 | ||||
| PDPK1 | PKN1 | up-regulates | phosphorylation | 9606 | 10753910 | ||||
| PDPK1 | AKT1 | up-regulates | phosphorylation | 9606 | 10226025 | ||||
| PDPK1 | SGK1 | up-regulates | phosphorylation | 9606 | 15209375 | ||||
| TLR4 | TLR4 | up-regulates | binding | 9606 | 24352680 | ||||
| TP53 | BAX | up-regulates | binding | 9606 | 16151013 | ||||
| MMP2 | TGFB1 | up-regulates | cleavage | 9606 | 10652271 | ||||
| IGF1R | PDPK1 | up-regulates | phosphorylation | 9606 | 20044479 | ||||
| TGFB1 | TGFBR1 | up-regulates | binding | 9606 | 26194464 | ||||
| ROCK2 | DPYSL2 | up-regulates | phosphorylation | 9606 | 10818093 | ||||
| PYCARD | BAX | up-regulates | relocalization | 9606 | 16964285 | ||||
| JAK2 | JAK2 | up-regulates | phosphorylation | 9606 | 20304997 | ||||
| MAPK8 | TP53 | up-regulates | phosphorylation | 9606 | 11896587 | ||||
| PDPK1 | AKT1 | up-regulates | phosphorylation | 9606 | 12167717 | ||||
| TGFB2 | TGFB2 | up-regulates | binding | 9606 | 16885528 | ||||
| PDPK1 | SGK1 | up-regulates | phosphorylation | 9606 | 10191262 | ||||
| JAK2 | STAT1 | up-regulates | phosphorylation | 9606 | 15322115 | ||||
| CCND1 | NOTCH1 | up-regulates | 9606 | 20443831 | |||||
| MAPK8 | SP1 | up-regulates | phosphorylation | 9606 | 19245816 | ||||
| MAPK8 | TP53 | up-regulates | phosphorylation | 9606 | 9724739 | ||||
| PDPK1 | AKT1 | up-regulates | phosphorylation | 9606 | 12808134 | ||||
| HIPK2 | TP53 | up-regulates | phosphorylation | 9606 | 17210684 | ||||
| ERN1 | JUN | up-regulates | 9606 | 18065414 | |||||
| PDPK1 | AKT1 | up-regulates | phosphorylation | 9606 | 10226025 | ||||
| PIK3C3 | AKT1 | up-regulates | 9606 | 10698680 | |||||
| HSP90AA1 | TGFBR1 | up-regulates | binding | 9606 | 18591668 | ||||
| PROS1 | AXL | up-regulates | binding | 9606 | 7867073 | ||||
| IGF1R | PDPK1 | up-regulates | phosphorylation | 9606 | 20643654 | ||||
| PIK3C3 | PTEN | up-regulates | binding | 9606 | 20212113 | ||||
| MAPK8 | BAX | up-regulates | 9606 | 15071501 | |||||
| MAPK8 | TP53 | up-regulates | phosphorylation | 9606 | 12531896 | ||||
| BMP4 | BMP4 | up-regulates | binding | 9606 | 11178121 | ||||
| IGF1R | PIK3R1 | up-regulates | binding | 9606 | 18595745 | ||||
| FYN | FYN | up-regulates | phosphorylation | 9606 | 22080863 | ||||
| JAK1 | STAT1 | up-regulates | phosphorylation | 9606 | 21576360 | ||||
| JAK2 | JAK2 | up-regulates | phosphorylation | 9606 | 20304997 | ||||
| PIK3C3 | AKT1 | up-regulates | relocalization | 9606 | 10698680 | ||||
| AKT1 | CTNNB1 | up-regulates | phosphorylation | 9606 | 17287208 | ||||
| TP53 | BAX | up-regulates | binding | 9606 | 14963330 | ||||
| JAK2 | STAT1 | up-regulates | phosphorylation | 9606 | 21576360 | ||||
| JAK2 | JAK2 | up-regulates | phosphorylation | 9606 | 15143187 | ||||
| IGF1R | PDPK1 | up-regulates | phosphorylation | 9606 | 20643654 | ||||
| FAS | FAS | up-regulates | binding | 9606 | 14585074 | ||||
| TGFB1 | PIK3R1 | up-regulates | binding | 9606 | 19114990 | ||||
| FAS | FAS | up-regulates | binding | 9606 | 19305384 | ||||
| IGF1R | IGF1R | up-regulates | phosphorylation | 9606 | 7493944 | ||||
| JAK1 | STAT6 | up-regulates | phosphorylation | 9606 | 9852261 | ||||
| PTEN | PTEN | up-regulates | dephosphorylation | 9606 | 22413754 | ||||
| TGFB1 | TGFBR1 | up-regulates | binding | 9606 | 22703233 | ||||
| JAK1 | STAT1 | up-regulates | phosphorylation | 9606 | 11823427 | ||||
| RHOA | MSN | up-regulates | phosphorylation | 9606 | 35267019 | ||||
| PARP1 | TP53 | up-regulates | relocalization | 9606 | 17891139 | ||||
| SMAD2 | SMAD2 | up-regulates | binding | 9606 | 9670020 | ||||
| PDPK1 | PDPK1 | up-regulates | phosphorylation | 9606 | 10455013 | ||||
| JAK2 | STAT6 | up-regulates | phosphorylation | 9606 | 18852293 | ||||
| JAK1 | STAT3 | up-regulates | phosphorylation | 9606 | 19723038 | ||||
| LEPR | STAT3 | up-regulates | binding | 9606 | 11018044 | ||||
| TLR4 | JUN | up-regulates | 9606 | 19592489 | |||||
| TGFB1 | TGFB1 | up-regulates | binding | 9606 | 16885528 | ||||
| TP53 | BAX | up-regulates | binding | 9606 | 14963330 | ||||
| JAK1 | STAT1 | up-regulates | phosphorylation | 9606 | 9020188 | ||||
| JAK2 | JAK2 | up-regulates | phosphorylation | 9606 | 15121872 | ||||
| C3 | C3 | up-regulates | cleavage | 9606 | 26806831 | ||||
| PTEN | PTEN | up-regulates | dephosphorylation | 9606 | 22413754 | ||||
| CDH3 | CTNNB1 | up-regulates | binding | 9606 | 21255999 | ||||
| JAK2 | STAT3 | up-regulates | phosphorylation | 9606 | 9575217 | ||||
| CDH6 | CTNNB1 | up-regulates | binding | 9606 | 21255999 | ||||
| LEPR | STAT3 | up-regulates | phosphorylation | 9606 | 18718905 | ||||
| JAK2 | LEPR | up-regulates | phosphorylation | 9606 | 11018044 | ||||
| TGFBR1 | SMAD2 | up-regulates | phosphorylation | 9606 | 10973958 | ||||
| TGFB1 | TGFBR1 | up-regulates | binding | 9606 | 22326956 | ||||
| MAPK8 | STAT3 | up-regulates | phosphorylation | 9606 | 23255093 | ||||
| PTEN | RAB7A | up-regulates | dephosphorylation | 9606 | 26869029 | ||||
| PDPK1 | PDPK1 | up-regulates | phosphorylation | 9606 | 11481331 | ||||
| TGFB1 | TGFBR1 | up-regulates | binding | 9606 | 22326956 | ||||
| NOTCH1 | HIF1A | up-regulates | relocalization | 9606 | 16256737 | ||||
| JAK1 | STAT6 | up-regulates | phosphorylation | 9606 | 23124025 | ||||
| HIPK2 | HIPK2 | up-regulates | phosphorylation | 9606 | 24145406 | ||||
| JAK2 | JAK2 | up-regulates | phosphorylation | 9606 | 20304997 | ||||
| PINK1 | UBC | up-regulates | phosphorylation | 9606 | 24784582 | ||||
| JAK1 | STAT3 | up-regulates | binding | 9606 | 24710148 | ||||
| JAK1 | STAT3 | up-regulates | phosphorylation | 9606 | 26260587 | ||||
| JAK2 | STAT6 | up-regulates | phosphorylation | 9606 | 9852261 | ||||
| RHOA | MAPK8 | up-regulates | binding | 9606 | 8824197 | ||||
| PTEN | PTEN | up-regulates | dephosphorylation | 9606 | 22413754 | ||||
| HIPK2 | HIPK2 | up-regulates | phosphorylation | 9606 | 24145406 | ||||
| LEPR | JAK2 | up-regulates | binding | 9606 | 18718905 | ||||
| JAK2 | JAK2 | up-regulates | phosphorylation | 9606 | 15143187 | ||||
| IGF1R | IGF1R | up-regulates | phosphorylation | 9606 | 7493944 | ||||
| HMGB1 | TLR4 | up-regulates | binding | 9606 | 20547845 | ||||
| JAK2 | STAT3 | up-regulates | phosphorylation | 9606 | 9575217 | ||||
| JAK2 | STAT5A | up-regulates | phosphorylation | 9606 | 9575217 | ||||
| STAT1 | STAT1 | up-regulates | binding | 9606 | 19041276 | ||||
| C3 | C3 | up-regulates | cleavage | 9606 | 26806831 | ||||
| JAK2 | LEPR | up-regulates | phosphorylation | 9606 | 11018044 | ||||
| TGFBR1 | RHOA | up-regulates | 9606 | 19726546 | |||||
| PDPK1 | AKT1 | up-regulates | phosphorylation | 9606 | 15718470 | ||||
| S100A9 | TLR4 | up-regulates | binding | 9606 | 28137827 | ||||
| JAK2 | JAK2 | up-regulates | phosphorylation | 9606 | 19364823 | ||||
| FBN1 | SMAD2 | up-regulates | 9606 | 17242066 | |||||
| HIPK2 | MECP2 | up-regulates | phosphorylation | 9606 | 19820693 | ||||
| BAX | BAX | up-regulates | binding | 9606 | 10629050 | ||||
| CKB | ACTB | up-regulates | relocalization | 9606 | 19333390 | ||||
| FBN1 | TGFB1 | up-regulates | binding | 9606 | 17242066 | ||||
| TP53 | FAS | up-regulates | transcriptional regulation | 9606 | 9841917 | ||||
| DDIT3 | TRIB3 | up-regulates | transcriptional regulation | 9606 | 18940792 | ||||
| TP53 | CDKN1A | up-regulates | transcriptional regulation | 9606 | 7566157 | ||||
| NOTCH1 | NOTCH1 | up-regulates | transcriptional regulation | 9606 | 16990763 | ||||
| CTNNB1 | CCND1 | up-regulates | transcriptional regulation | 9606 | 30519351 | ||||
| IKBKB | HES1 | up-regulates | transcriptional regulation | 9606 | 22056382 | ||||
| TP53 | VCAN | up-regulates | transcriptional regulation | 9606 | 12438652 | ||||
| CTNNB1 | CCND1 | up-regulates | transcriptional regulation | 9606 | 12589056 | ||||
| SP1 | TNC | up-regulates | transcriptional regulation | 9606 | 15001984 | ||||
| HIF1A | CCL2 | up-regulates | transcriptional regulation | 9606 | 17474992 | ||||
| PTEN | DUSP1 | up-regulates | transcriptional regulation | 9606 | 11494141 | ||||
| AKT1 | SLC2A1 | up-regulates | transcriptional regulation | 9606 | 8940145 | ||||
| SP1 | SOD1 | up-regulates | transcriptional regulation | 9606 | 8921911 | ||||
| STAT1 | TLR3 | up-regulates | transcriptional regulation | 9606 | 16628196 | ||||
| EGR1 | GDF15 | up-regulates | transcriptional regulation | 9606 | 17715378 | ||||
| CTNNB1 | CCND1 | up-regulates | transcriptional regulation | 9606 | 15735151 | ||||
| STAT3 | CCND1 | up-regulates | transcriptional regulation | 9606 | 16510571 | ||||
| F2RL1 | THBS1 | up-regulates | transcriptional regulation | 9606 | 21072196 | ||||
| FOXO1 | PCK1 | up-regulates | transcriptional regulation | 9606 | 22521266 | ||||
| PTEN | PINK1 | up-regulates | transcriptional regulation | 9606 | 11494141 | ||||
| STAT6 | PPARA | up-regulates | transcriptional regulation | 9606 | 20508200 | ||||
| F2RL1 | F2RL1 | up-regulates | transcriptional regulation | 9606 | 21072196 |
