Selected Cell
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Value:
Principal_Cell_interactions
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| ENTITYA | ENTITYB | EFFECT | MECHANISM | TAX_ID | PMID | ||||
| MDM2 | EP300 | down-regulates | binding | 9606 | 11070080 | ||||
| MAPK1 | SMAD1 | down-regulates | phosphorylation | 9606 | 9335504 | ||||
| MAPK1 | DUSP1 | down-regulates | phosphorylation | 9606 | 16286470 | ||||
| MAPK1 | SMAD2 | down-regulates | phosphorylation | 9606 | 10197981 | ||||
| AKT1 | FOXO1 | down-regulates | phosphorylation | 9606 | 11237865 | ||||
| SIRT1 | TP53 | down-regulates | deacetylation | 9606 | 19047049 | ||||
| SOCS1 | JAK1 | down-regulates | binding | 9606 | 11133764 | ||||
| PTPN13 | INSR | down-regulates | dephosphorylation | 9606 | 15611135 | ||||
| PKN1 | FOXO1 | down-regulates | phosphorylation | 9606 | 12560069 | ||||
| MAPK1 | PPARG | down-regulates | relocalization | 9606 | 18596912 | ||||
| PTPN6 | STAT6 | down-regulates | 9606 | 9852037 | |||||
| MAPK1 | SMAD1 | down-regulates | phosphorylation | 9606 | 9335504 | ||||
| PTPN6 | INSR | down-regulates | dephosphorylation | 9606 | 10734133 | ||||
| SRC | PTEN | down-regulates | phosphorylation | 9606 | 12869565 | ||||
| SIRT1 | EP300 | down-regulates | deacetylation | 9606 | 19047049 | ||||
| SIRT1 | NOTCH1 | down-regulates | deacetylation | 9606 | 22223095 | ||||
| SIRT1 | EP300 | down-regulates | deacetylation | 9606 | 19047049 | ||||
| PTPN6 | EGFR | down-regulates | dephosphorylation | 9606 | 9733788 | ||||
| PTPN13 | INSR | down-regulates | dephosphorylation | 9606 | 15611135 | ||||
| PTPN6 | INSR | down-regulates | dephosphorylation | 9606 | 10734133 | ||||
| PTPN6 | INSR | down-regulates | dephosphorylation | 9606 | 10734133 | ||||
| MAPK1 | SMAD1 | down-regulates | phosphorylation | 9606 | 19914161 | ||||
| MAPK1 | TSC2 | down-regulates | phosphorylation | 9606 | 15851026 | ||||
| SRC | DAG1 | down-regulates | phosphorylation | 9606 | 12795607 | ||||
| CTNNB1 | PPARG | down-regulates | 9606 | 10937998 | |||||
| HSP90AA1 | NR3C1 | down-regulates | binding | 9606 | 21511880 | ||||
| DUSP1 | MAPK1 | down-regulates | dephosphorylation | 9606 | 10617468 | ||||
| MAPK1 | DUSP1 | down-regulates | phosphorylation | 9606 | 16286470 | ||||
| MAPK1 | SMAD3 | down-regulates | phosphorylation | 9606 | 19914168 | ||||
| MAPK1 | SMAD1 | down-regulates | phosphorylation | 9606 | 19914161 | ||||
| MAPK1 | PPARG | down-regulates | phosphorylation | 9606 | 18596912 | ||||
| AKT1 | FAS | down-regulates | 9606 | 15004527 | |||||
| MAPK1 | SMAD1 | down-regulates | phosphorylation | 9606 | 19914161 | ||||
| PTPN13 | INSR | down-regulates | dephosphorylation | 9606 | 15611135 | ||||
| JAK2 | JAK2 | down-regulates | phosphorylation | 9606 | 19364823 | ||||
| MAPK1 | SMAD3 | down-regulates | phosphorylation | 9606 | 10197981 | ||||
| PRKAA1 | EP300 | down-regulates | phosphorylation | 9606 | 21940946 | ||||
| MAPK1 | SMAD1 | down-regulates | phosphorylation | 9606 | 19914168 | ||||
| MAPK1 | SMAD3 | down-regulates | phosphorylation | 9606 | 19914161 | ||||
| MAPK1 | SMAD1 | down-regulates | phosphorylation | 9606 | 9335504 | ||||
| AKT1 | SMAD3 | down-regulates | binding | 9606 | 15048128 | ||||
| JAK2 | MAP3K5 | down-regulates | phosphorylation | 9606 | 19287004 | ||||
| AKT1 | YAP1 | down-regulates | phosphorylation | 9606 | 12535517 | ||||
| PRKAA1 | TGFB1 | down-regulates | 9606 | 23324179 | |||||
| MAPK1 | SMAD1 | down-regulates | phosphorylation | 9606 | 19914168 | ||||
| PTPN6 | INSR | down-regulates | dephosphorylation | 9606 | 10734133 | ||||
| PTPN13 | INSR | down-regulates | dephosphorylation | 9606 | 15611135 | ||||
| PRKAA1 | HDAC4 | down-regulates | phosphorylation | 9606 | 21565617 | ||||
| AKT1 | CASP9 | down-regulates | phosphorylation | 9606 | 15004527 | ||||
| PTPN6 | JAK1 | down-regulates | dephosphorylation | 9606 | 14624462 | ||||
| MAPK1 | SMAD3 | down-regulates | phosphorylation | 9606 | 10197981 | ||||
| SOCS1 | JAK1 | down-regulates | binding | 9606 | 23663276 | ||||
| AKT1 | FOXO1 | down-regulates | phosphorylation | 9606 | 21798082 | ||||
| AKT1 | NR3C1 | down-regulates | phosphorylation | 9606 | 24291004 | ||||
| AKT1 | CASP9 | down-regulates | phosphorylation | 9606 | 10529400 | ||||
| RPS6KA3 | MAP3K5 | down-regulates | phosphorylation | 9606 | 23608533 | ||||
| RPS6KA3 | HMGN1 | down-regulates | phosphorylation | 9606 | 11438671 | ||||
| MAPK1 | SMAD3 | down-regulates | phosphorylation | 9606 | 19914161 | ||||
| AKT1 | MAP3K5 | down-regulates | phosphorylation | 9606 | 11154276 | ||||
| STAT6 | STAT1 | down-regulates | binding | 9606 | 10982806 | ||||
| JAK2 | JAK2 | down-regulates | phosphorylation | 9606 | 21841788 | ||||
| IKBKB | IKBKB | down-regulates | phosphorylation | 9606 | 10195894 | ||||
| PTEN | AKT1 | down-regulates | 9606 | 19903340 | |||||
| IKBKB | IKBKB | down-regulates | phosphorylation | 9606 | 10195894 | ||||
| IKBKB | IKBKB | down-regulates | phosphorylation | 9606 | 10195894 | ||||
| PKN1 | EGFR | down-regulates | phosphorylation | 9606 | 21749319 | ||||
| IKBKB | IKBKB | down-regulates | phosphorylation | 9606 | 10195894 | ||||
| JAK2 | JAK2 | down-regulates | phosphorylation | 9606 | 15143187 | ||||
| RNF7 | JUN | down-regulates | ubiquitination | 9606 | 23136067 | ||||
| MAPK1 | CASP9 | down-regulates | phosphorylation | 9606 | 12792650 | ||||
| SOCS3 | JAK1 | down-regulates | binding | 9606 | 23454976 | ||||
| IKBKB | IKBKB | down-regulates | phosphorylation | 9606 | 10195894 | ||||
| RNF7 | HIF1A | down-regulates | ubiquitination | 9606 | 23136067 | ||||
| RPS6KA3 | HMGN1 | down-regulates | phosphorylation | 9606 | 11438671 | ||||
| RPS6KA3 | MAP3K5 | down-regulates | phosphorylation | 9606 | 23608533 | ||||
| PTEN | AKT1 | down-regulates | 9606 | 20596030 | |||||
| PTEN | RPS6KB1 | down-regulates | dephosphorylation | 9606 | 19436944 | ||||
| IKBKB | IKBKB | down-regulates | phosphorylation | 9606 | 10195894 | ||||
| EGFR | PKM | down-regulates | phosphorylation | 9606 | 26759242 | ||||
| MAPK1 | SMAD3 | down-regulates | phosphorylation | 9606 | 19914161 | ||||
| IKBKB | IKBKB | down-regulates | phosphorylation | 9606 | 10195894 | ||||
| SRC | CTNNB1 | down-regulates | phosphorylation | 9606 | 11279024 | ||||
| SOCS3 | JAK2 | down-regulates | binding | 9606 | 24600449 | ||||
| AKT1 | RPS6KA3 | down-regulates | phosphorylation | 9606 | 33574926 | ||||
| IKBKB | IKBKB | down-regulates | phosphorylation | 9606 | 10195894 | ||||
| MAPK1 | SMAD3 | down-regulates | phosphorylation | 9606 | 10197981 | ||||
| PTEN | SRC | down-regulates | dephosphorylation | 9606 | 22482061 | ||||
| PTPN6 | PKM | down-regulates | dephosphorylation | 9606 | 26959741 | ||||
| MAPK1 | SMAD1 | down-regulates | phosphorylation | 9606 | 9335504 | ||||
| RPS6KA3 | MAP3K5 | down-regulates | phosphorylation | 9606 | 23608533 | ||||
| JAK2 | JAK2 | down-regulates | phosphorylation | 9606 | 21841788 | ||||
| IKBKB | IKBKB | down-regulates | phosphorylation | 9606 | 10195894 | ||||
| PPARG | PTEN | down-regulates | 9606 | 23128507 | |||||
| MAPK1 | SMAD1 | down-regulates | phosphorylation | 9606 | 19914161 | ||||
| JUN | SMAD3 | down-regulates | binding | 9606 | 10871633 | ||||
| SRC | PDCD6IP | down-regulates | phosphorylation | 9606 | 15557335 | ||||
| DUSP1 | JUN | down-regulates | dephosphorylation | 9606 | 26734995 | ||||
| IKBKB | IKBKB | down-regulates | phosphorylation | 9606 | 10195894 | ||||
| IKBKB | IKBKB | down-regulates | phosphorylation | 9606 | 10195894 | ||||
| SRC | SRC | down-regulates | phosphorylation | 9606 | 8755732 | ||||
| PTEN | PIK3CA | down-regulates | 9606 | 18794881 | |||||
| PTPN13 | SRC | down-regulates | dephosphorylation | 9606 | 19307596 | ||||
| IKBKB | IKBKB | down-regulates | phosphorylation | 9606 | 10195894 | ||||
| TRIB3 | AKT1 | down-regulates | binding | 9606 | 12791994 | ||||
| IKBKB | IKBKB | down-regulates | phosphorylation | 9606 | 10195894 | ||||
| IKBKB | IKBKB | down-regulates | phosphorylation | 9606 | 10195894 | ||||
| PTEN | SP1 | down-regulates | dephosphorylation | 9606 | 21603612 | ||||
| EGFR | ABCA1 | down-regulates | phosphorylation | 9606 | 12196520 | ||||
| SRC | ENG | down-regulates | phosphorylation | 9606 | 25070888 | ||||
| MDM2 | CDKN1A | down-regulates | binding | 9606 | 14761977 | ||||
| SRC | ENG | down-regulates | phosphorylation | 9606 | 25070888 | ||||
| MAPK1 | TXNIP | down-regulates | phosphorylation | 9606 | 31320475 | ||||
| MAPK1 | CDKN1A | down-regulates | phosphorylation | 9606 | 19364816 | ||||
| EGFR | PPARG | down-regulates | phosphorylation | 9606 | 26718225 | ||||
| MAPK1 | NR3C2 | down-regulates | phosphorylation | 9606 | 22798426 | ||||
| SRC | TP53 | down-regulates | phosphorylation | 9606 | 25071020 | ||||
| MAPK1 | NR3C2 | down-regulates | phosphorylation | 9606 | 22798426 | ||||
| EP300 | TP53 | down-regulates | polyubiquitination | 9606 | 12690203 | ||||
| MYLIP | VLDLR | down-regulates | ubiquitination | 9606 | 20427281 | ||||
| MDM2 | TP53 | down-regulates | ubiquitination | 9606 | 23150757 | ||||
| CLU | IKBKB | down-regulates | binding | 9606 | 20068069 | ||||
| MDM2 | HIF1A | down-regulates | ubiquitination | 9606 | 10640274 | ||||
| SIRT1 | TP53 | down-regulates | deacetylation | 9606 | 25280219 | ||||
| MAPK1 | NR3C2 | down-regulates | phosphorylation | 9606 | 22798426 | ||||
| PTPN6 | CTNNB1 | down-regulates | dephosphorylation | 9606 | 20840866 | ||||
| PTPN6 | CTNNB1 | down-regulates | dephosphorylation | 9606 | 20840866 | ||||
| JAK2 | MAP3K5 | down-regulates | phosphorylation | 9606 | 19287004 | ||||
| MYLIP | LDLR | down-regulates | ubiquitination | 9606 | 30896554 | ||||
| SRC | SIRT2 | down-regulates | phosphorylation | 9606 | 24996174 | ||||
| SRC | TP53 | down-regulates | phosphorylation | 9606 | 25071020 | ||||
| MAPK1 | NR3C2 | down-regulates | phosphorylation | 9606 | 22798426 | ||||
| MDM2 | TP53 | down-regulates | ubiquitination | 9606 | 10935507 | ||||
| MAPK1 | NR3C2 | down-regulates | phosphorylation | 9606 | 22798426 | ||||
| SOCS1 | JAK2 | down-regulates | ubiquitination | 9606 | 14522994 | ||||
| MAPK1 | NR3C2 | down-regulates | phosphorylation | 9606 | 22798426 | ||||
| AKT1 | FOXO1 | down-regulates | phosphorylation | 9606 | 21440011 | ||||
| MAPK1 | PPARG | down-regulates | phosphorylation | 9606 | 11733495 | ||||
| MDM2 | TP53 | down-regulates | ubiquitination | 9606 | 22337874 | ||||
| MDM2 | PPARG | down-regulates | ubiquitination | 9606 | 26718225 | ||||
| MAPK1 | CDKN1A | down-regulates | phosphorylation | 9606 | 19364816 | ||||
| SOX6 | CTNNB1 | down-regulates | binding | 9606 | 26893351 | ||||
| SOCS1 | STAT1 | down-regulates | transcriptional regulation | 9606 | 16628196 | ||||
| EGR1 | FAS | down-regulates | transcriptional regulation | 9606 | 9300687 | ||||
| TP53 | SLC2A1 | down-regulates | transcriptional regulation | 9606 | 27692180 | ||||
| F2RL1 | TXNIP | down-regulates | transcriptional regulation | 9606 | 21072196 | ||||
| PPARG | GLS | down-regulates | transcriptional regulation | 9606 | 33754076 | ||||
| NR3C1 | JUN | down-regulates | transcriptional regulation | 9606 | 8639160 | ||||
| MDM2 | CDKN1A | down-regulates | 9606 | 18292944 | |||||
| F2RL1 | CTSD | down-regulates | transcriptional regulation | 9606 | 21072196 | ||||
| PRKAA1 | CDKN1A | down-regulates | transcriptional regulation | 9606 | 19491292 | ||||
| HDAC4 | CDH1 | down-regulates | transcriptional regulation | 9606 | 25726523 | ||||
| PPARG | CTNNB1 | down-regulates | transcriptional regulation | 9606 | 20303941 | ||||
| SIRT1 | PPARG | down-regulates | transcriptional regulation | 9606 | 21633182 | ||||
| EGR1 | PPARG | down-regulates | transcriptional regulation | 9606 | 29212876 | ||||
| SIRT2 | CDKN1A | down-regulates | transcriptional regulation | 9606 | 14522900 | ||||
| SRC | PROM1 | unknown | phosphorylation | 9606 | 19296573 | ||||
| SRC | PROM1 | unknown | phosphorylation | 9606 | 19296573 | ||||
| SRC | RPS6KA3 | unknown | phosphorylation | 9606 | 18156174 | ||||
| MAPK1 | SMAD3 | unknown | phosphorylation | 9606 | 15241418 | ||||
| MAPK1 | SMAD3 | unknown | phosphorylation | 9606 | 19914168 | ||||
| MAPK1 | SMAD3 | unknown | phosphorylation | 9606 | 15241418 | ||||
| PRKAA1 | FOXO1 | up-regulates | phosphorylation | 9606 | 17900900 | ||||
| EGFR | STAT1 | up-regulates | phosphorylation | 9606 | 22693070 | ||||
| INSR | PTPN6 | up-regulates | phosphorylation | 9606 | 7512963 | ||||
| MDM2 | NOTCH1 | up-regulates | ubiquitination | 9606 | 23252402 | ||||
| SRC | SRC | up-regulates | phosphorylation | 9606 | 7578094 | ||||
| EGFR | STAT1 | up-regulates | phosphorylation | 9606 | 14967450 | ||||
| MAPK1 | SP1 | up-regulates | phosphorylation | 9606 | 11904305 | ||||
| AKT1 | MDM2 | up-regulates | phosphorylation | 9606 | 15169778 | ||||
| MAPK1 | DUSP1 | up-regulates | phosphorylation | 9606 | 10617468 | ||||
| SRC | PTPN6 | up-regulates | phosphorylation | 9606 | 14699166 | ||||
| PRKAA1 | TP53 | up-regulates | phosphorylation | 9606 | 15866171 | ||||
| SMAD1 | SMAD4 | up-regulates | binding | 9606 | 21454478 | ||||
| MAPK1 | SP1 | up-regulates | phosphorylation | 9606 | 19318349 | ||||
| MAPK1 | RPS6KB1 | up-regulates | phosphorylation | 9606 | 14967450 | ||||
| MAPK1 | RPS6KB1 | up-regulates | phosphorylation | 9606 | 19085255 | ||||
| MAPK1 | PRDX6 | up-regulates | phosphorylation | 9606 | 19140803 | ||||
| MAPK1 | SMAD4 | up-regulates | phosphorylation | 9606 | 12801888 | ||||
| NR3C1 | NR3C2 | up-regulates | 9606 | 11154266 | |||||
| MAPK1 | SMAD2 | up-regulates | phosphorylation | 9606 | 12193595 | ||||
| MAPK1 | RPS6KB1 | up-regulates | phosphorylation | 9606 | 21035469 | ||||
| MAPK1 | EP300 | up-regulates | phosphorylation | 9606 | 17623675 | ||||
| EP300 | DUSP1 | up-regulates | acetylation | 9606 | 20626350 | ||||
| SRC | CLTC | up-regulates | phosphorylation | 9606 | 10089883 | ||||
| EP300 | SMAD1 | up-regulates | binding | 9606 | 12419246 | ||||
| MAPK1 | SMAD2 | up-regulates | phosphorylation | 9606 | 12193595 | ||||
| YAP1 | SMAD1 | up-regulates | binding | 9606 | 23431053 | ||||
| MAPK1 | SP1 | up-regulates | phosphorylation | 9606 | 11904305 | ||||
| EP300 | TP53 | up-regulates | acetylation | 9606 | 11070080 | ||||
| MMP2 | TGFB1 | up-regulates | cleavage | 9606 | 10652271 | ||||
| SRC | IKBKB | up-regulates | phosphorylation | 9606 | 12645577 | ||||
| SRC | PTPN6 | up-regulates | phosphorylation | 9606 | 14699166 | ||||
| ROCK2 | DPYSL2 | up-regulates | phosphorylation | 9606 | 10818093 | ||||
| MAPK1 | SP1 | up-regulates | phosphorylation | 9606 | 11904305 | ||||
| MAP3K5 | CDKN1A | up-regulates | phosphorylation | 9606 | 17325029 | ||||
| MAPK1 | HIF1A | up-regulates | phosphorylation | 9606 | 18519666 | ||||
| MAPK1 | DUSP1 | up-regulates | phosphorylation | 9606 | 10617468 | ||||
| JAK2 | JAK2 | up-regulates | phosphorylation | 9606 | 20304997 | ||||
| MAPK1 | SMAD2 | up-regulates | phosphorylation | 9606 | 12193595 |
