Selected Cell
Cell:
Value:
PathwayEnrichmentResults_Top30
PathwayNetwork_Top30
A
B
C
D
E
F
G
H
I
J
K
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
| id | geneSet | link | size | overlap | expect | enrichmentRatio | pValue | FDR | gene_count | genes |
| AKT phosphorylates targets in the cytosol | R-HSA-198323 | http://reactome.org/PathwayBrowser/#/R-HSA-198323 | 14 | 4 | 0.0795982185160617 | 50.2523809523809 | 9.05750467294908E-7 | 6.17721818695127E-5 | 4 | AKT1;BAD;CDKN1A;MDM2 |
| Activation of BAD and translocation to mitochondria | R-HSA-111447 | http://reactome.org/PathwayBrowser/#/R-HSA-111447 | 15 | 4 | 0.0852838055529233 | 46.9022222222222 | 1.22987416517617E-6 | 7.48905518437632E-5 | 4 | AKT1;BAD;BCL2;YWHAZ |
| Apoptotic cleavage of cell adhesion proteins | R-HSA-351906 | http://reactome.org/PathwayBrowser/#/R-HSA-351906 | 11 | 2 | 0.0625414574054771 | 31.9787878787878 | 0.0016917148383395 | 0.0210538233530575 | 2 | CASP3;CTNNB1 |
| BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members | R-HSA-111453 | http://reactome.org/PathwayBrowser/#/R-HSA-111453 | 9 | 3 | 0.051170283331754 | 58.6277777777777 | 1.43262005806166E-5 | 5.31003738911985E-4 | 3 | BAD;BCL2;STAT3 |
| CLEC7A/inflammasome pathway | R-HSA-5660668 | http://reactome.org/PathwayBrowser/#/R-HSA-5660668 | 6 | 2 | 0.0341135222211693 | 58.6277777777777 | 4.69904421565692E-4 | 0.0080927983714091 | 2 | PYCARD;RELA |
| Caspase-mediated cleavage of cytoskeletal proteins | R-HSA-264870 | http://reactome.org/PathwayBrowser/#/R-HSA-264870 | 12 | 2 | 0.0682270444423386 | 29.3138888888888 | 0.0020226443361123 | 0.023459922401847 | 2 | CASP3;VIM |
| Cross-presentation of particulate exogenous antigens (phagosomes) | R-HSA-1236973 | http://reactome.org/PathwayBrowser/#/R-HSA-1236973 | 8 | 2 | 0.0454846962948924 | 43.9708333333333 | 8.7074884453131E-4 | 0.0133750160353683 | 2 | CYBA;NCF1 |
| Growth hormone receptor signaling | R-HSA-982772 | http://reactome.org/PathwayBrowser/#/R-HSA-982772 | 24 | 4 | 0.136454088884677 | 29.3138888888888 | 9.21484748128698E-6 | 4.24630133934981E-4 | 4 | PTPN6;SOCS3;STAT1;STAT3 |
| HSF1 activation | R-HSA-3371511 | http://reactome.org/PathwayBrowser/#/R-HSA-3371511 | 12 | 2 | 0.0682270444423386 | 29.3138888888888 | 0.0020226443361123 | 0.023459922401847 | 2 | HSP90AA1;VCP |
| Inflammasomes | R-HSA-622312 | http://reactome.org/PathwayBrowser/#/R-HSA-622312 | 20 | 4 | 0.113711740737231 | 35.1766666666666 | 4.27358468335636E-6 | 2.27701933910081E-4 | 4 | BCL2;PYCARD;RELA;TXN |
| InlA-mediated entry of Listeria monocytogenes into host cells | R-HSA-8876493 | http://reactome.org/PathwayBrowser/#/R-HSA-8876493 | 9 | 2 | 0.051170283331754 | 39.0851851851851 | 0.0011154410285172 | 0.0154620077530235 | 2 | CTNNB1;UBC |
| Interleukin-15 signaling | R-HSA-8983432 | http://reactome.org/PathwayBrowser/#/R-HSA-8983432 | 14 | 3 | 0.0795982185160617 | 37.6892857142857 | 6.08345162840251E-5 | 0.0016206695353791 | 3 | JAK1;JAK3;STAT3 |
| Interleukin-2 signaling | R-HSA-9020558 | http://reactome.org/PathwayBrowser/#/R-HSA-9020558 | 12 | 2 | 0.0682270444423386 | 29.3138888888888 | 0.0020226443361123 | 0.023459922401847 | 2 | JAK1;JAK3 |
| Interleukin-27 signaling | R-HSA-9020956 | http://reactome.org/PathwayBrowser/#/R-HSA-9020956 | 11 | 3 | 0.0625414574054771 | 47.9681818181818 | 2.79134431084848E-5 | 9.1523885576859E-4 | 3 | JAK1;STAT1;STAT3 |
| Interleukin-6 signaling | R-HSA-1059683 | http://reactome.org/PathwayBrowser/#/R-HSA-1059683 | 11 | 4 | 0.0625414574054771 | 63.9575757575757 | 3.02432829890619E-7 | 2.45546654744527E-5 | 4 | JAK1;SOCS3;STAT1;STAT3 |
| Interleukin-9 signaling | R-HSA-8985947 | http://reactome.org/PathwayBrowser/#/R-HSA-8985947 | 9 | 4 | 0.051170283331754 | 78.1703703703703 | 1.16460898369474E-7 | 1.16803430423502E-5 | 4 | JAK1;JAK3;STAT1;STAT3 |
| Josephin domain DUBs | R-HSA-5689877 | http://reactome.org/PathwayBrowser/#/R-HSA-5689877 | 12 | 2 | 0.0682270444423386 | 29.3138888888888 | 0.0020226443361123 | 0.023459922401847 | 2 | UBC;VCP |
| LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production | R-HSA-3134973 | http://reactome.org/PathwayBrowser/#/R-HSA-3134973 | 5 | 2 | 0.0284279351843077 | 70.3533333333333 | 3.14420538009341E-4 | 0.0057030533755949 | 2 | CTNNB1;IRF3 |
| NF-kB is activated and signals survival | R-HSA-209560 | http://reactome.org/PathwayBrowser/#/R-HSA-209560 | 13 | 3 | 0.0739126314792002 | 40.5884615384615 | 4.79926378946782E-5 | 0.001341433567384 | 3 | IRAK1;RELA;UBC |
| PI3K/AKT activation | R-HSA-198203 | http://reactome.org/PathwayBrowser/#/R-HSA-198203 | 9 | 2 | 0.051170283331754 | 39.0851851851851 | 0.0011154410285172 | 0.0154620077530235 | 2 | PIK3CA;RHOA |
| PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 | R-HSA-8849469 | http://reactome.org/PathwayBrowser/#/R-HSA-8849469 | 9 | 2 | 0.051170283331754 | 39.0851851851851 | 0.0011154410285172 | 0.0154620077530235 | 2 | AKT1;UBC |
| RHO GTPases Activate NADPH Oxidases | R-HSA-5668599 | http://reactome.org/PathwayBrowser/#/R-HSA-5668599 | 13 | 3 | 0.0739126314792002 | 40.5884615384615 | 4.79926378946782E-5 | 0.001341433567384 | 3 | CYBA;NCF1;RAC1 |
| Regulation of IFNG signaling | R-HSA-877312 | http://reactome.org/PathwayBrowser/#/R-HSA-877312 | 14 | 4 | 0.0795982185160617 | 50.2523809523809 | 9.05750467294908E-7 | 6.17721818695127E-5 | 4 | JAK1;PTPN6;SOCS3;STAT1 |
| Regulation of PTEN localization | R-HSA-8948747 | http://reactome.org/PathwayBrowser/#/R-HSA-8948747 | 9 | 2 | 0.051170283331754 | 39.0851851851851 | 0.0011154410285172 | 0.0154620077530235 | 2 | PTEN;UBC |
| Sema4D mediated inhibition of cell attachment and migration | R-HSA-416550 | http://reactome.org/PathwayBrowser/#/R-HSA-416550 | 8 | 2 | 0.0454846962948924 | 43.9708333333333 | 8.7074884453131E-4 | 0.0133750160353683 | 2 | RAC1;RHOA |
| Signaling by Leptin | R-HSA-2586552 | http://reactome.org/PathwayBrowser/#/R-HSA-2586552 | 11 | 2 | 0.0625414574054771 | 31.9787878787878 | 0.0016917148383395 | 0.0210538233530575 | 2 | SOCS3;STAT3 |
| Signaling by cytosolic FGFR1 fusion mutants | R-HSA-1839117 | http://reactome.org/PathwayBrowser/#/R-HSA-1839117 | 18 | 3 | 0.102340566663508 | 29.3138888888888 | 1.34184608475695E-4 | 0.003010325755935 | 3 | PIK3CA;STAT1;STAT3 |
| Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation | R-HSA-1474151 | http://reactome.org/PathwayBrowser/#/R-HSA-1474151 | 12 | 3 | 0.0682270444423386 | 43.9708333333333 | 3.70673494757278E-5 | 0.0011285684081449 | 3 | AKT1;CALM1;HSP90AA1 |
| The NLRP3 inflammasome | R-HSA-844456 | http://reactome.org/PathwayBrowser/#/R-HSA-844456 | 15 | 3 | 0.0852838055529233 | 35.1766666666666 | 7.57356768137373E-5 | 0.0019273034174242 | 3 | PYCARD;RELA;TXN |
| VEGFR2 mediated vascular permeability | R-HSA-5218920 | http://reactome.org/PathwayBrowser/#/R-HSA-5218920 | 29 | 5 | 0.164882024068985 | 30.3247126436781 | 5.36181854471351E-7 | 4.15540937215297E-5 | 5 | AKT1;CALM1;CTNNB1;HSP90AA1;RAC1 |
A
B
C
D
E
F
G
H
I
J
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
| Note: Edges are drawn between pathways based on their common genes, and the edge width is based on the number of those genes. | |||||||||
