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Macula_Densa_interactions
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| ENTITYA | ENTITYB | EFFECT | MECHANISM | TAX_ID | PMID | ||||
| HDAC1 | RELA | down-regulates | binding | 9606 | 17183360 | ||||
| MAPK1 | RORA | down-regulates | phosphorylation | 9606 | 17512500 | ||||
| MAPK1 | DUSP1 | down-regulates | phosphorylation | 9606 | 16286470 | ||||
| FOXO1 | PPARGC1A | down-regulates | 9606 | 20577053 | |||||
| MAPK1 | SMAD2 | down-regulates | phosphorylation | 9606 | 10197981 | ||||
| AKT1 | FOXO1 | down-regulates | phosphorylation | 9606 | 11237865 | ||||
| PTPN13 | INSR | down-regulates | dephosphorylation | 9606 | 15611135 | ||||
| CASP3 | IKBKB | down-regulates | cleavage | 9606 | 11741536 | ||||
| RPS6KB1 | HSPB1 | down-regulates | phosphorylation | 9606 | 19593530 | ||||
| PRKCZ | CASP9 | down-regulates | phosphorylation | 9606 | 16287866 | ||||
| SRC | PTEN | down-regulates | phosphorylation | 9606 | 12869565 | ||||
| PTPN13 | INSR | down-regulates | dephosphorylation | 9606 | 15611135 | ||||
| CASP3 | IKBKB | down-regulates | cleavage | 9606 | 11741536 | ||||
| RPS6KB1 | HSPB1 | down-regulates | phosphorylation | 9606 | 19593530 | ||||
| STAT1 | RELA | down-regulates | binding | 9606 | 16481475 | ||||
| INSR | CALM1 | down-regulates | phosphorylation | 9606 | 3415247 | ||||
| SRC | DAG1 | down-regulates | phosphorylation | 9606 | 12795607 | ||||
| FOXO1 | PPARGC1A | down-regulates | 9606 | 16308421 | |||||
| HSP90AA1 | NR3C1 | down-regulates | binding | 9606 | 21511880 | ||||
| DUSP1 | MAPK1 | down-regulates | dephosphorylation | 9606 | 10617468 | ||||
| MAPK1 | DUSP1 | down-regulates | phosphorylation | 9606 | 16286470 | ||||
| MAPK1 | SMAD3 | down-regulates | phosphorylation | 9606 | 19914168 | ||||
| EGFR | CALM1 | down-regulates | phosphorylation | 9606 | 7925415 | ||||
| AKT1 | FAS | down-regulates | 9606 | 15004527 | |||||
| PTPN13 | INSR | down-regulates | dephosphorylation | 9606 | 15611135 | ||||
| MAPK1 | SMAD3 | down-regulates | phosphorylation | 9606 | 10197981 | ||||
| PRKAA1 | EP300 | down-regulates | phosphorylation | 9606 | 21940946 | ||||
| MAPK1 | SMAD3 | down-regulates | phosphorylation | 9606 | 19914161 | ||||
| CASP3 | IKBKB | down-regulates | cleavage | 9606 | 11741536 | ||||
| PTEN | STAT5A | down-regulates | dephosphorylation | 9606 | 20596030 | ||||
| CASP3 | IKBKB | down-regulates | cleavage | 9606 | 11741536 | ||||
| AKT1 | SMAD3 | down-regulates | binding | 9606 | 15048128 | ||||
| RPS6KB1 | HSPB1 | down-regulates | phosphorylation | 9606 | 19593530 | ||||
| AKT1 | YAP1 | down-regulates | phosphorylation | 9606 | 12535517 | ||||
| HSPB1 | CASP3 | down-regulates | 9606 | 10544189 | |||||
| PTPN13 | INSR | down-regulates | dephosphorylation | 9606 | 15611135 | ||||
| AKT1 | CASP9 | down-regulates | phosphorylation | 9606 | 15004527 | ||||
| EGFR | CALM1 | down-regulates | phosphorylation | 9606 | 3415247 | ||||
| AKT1 | HSPB1 | down-regulates | phosphorylation | 9606 | 19593530 | ||||
| CDKN1A | PCNA | down-regulates | binding | 9606 | 22911014 | ||||
| MAPK1 | SMAD3 | down-regulates | phosphorylation | 9606 | 10197981 | ||||
| AKT1 | FOXO1 | down-regulates | phosphorylation | 9606 | 21798082 | ||||
| AKT1 | NR3C1 | down-regulates | phosphorylation | 9606 | 24291004 | ||||
| AKT1 | CASP9 | down-regulates | phosphorylation | 9606 | 10529400 | ||||
| MAPK1 | SMAD3 | down-regulates | phosphorylation | 9606 | 19914161 | ||||
| STAT6 | STAT1 | down-regulates | binding | 9606 | 10982806 | ||||
| SRC | RHOA | down-regulates | phosphorylation | 9606 | 23027962 | ||||
| SRC | RRAS | down-regulates | phosphorylation | 9606 | 11682467 | ||||
| IKBKB | IKBKB | down-regulates | phosphorylation | 9606 | 10195894 | ||||
| PTEN | AKT1 | down-regulates | 9606 | 19903340 | |||||
| IKBKB | IKBKB | down-regulates | phosphorylation | 9606 | 10195894 | ||||
| IKBKB | IKBKB | down-regulates | phosphorylation | 9606 | 10195894 | ||||
| IKBKB | IKBKB | down-regulates | phosphorylation | 9606 | 10195894 | ||||
| MAPK1 | CASP9 | down-regulates | phosphorylation | 9606 | 12792650 | ||||
| AKT1 | BAX | down-regulates | phosphorylation | 9606 | 14766748 | ||||
| PRKCZ | BAX | down-regulates | phosphorylation | 9606 | 17525161 | ||||
| STK11 | PTEN | down-regulates | phosphorylation | 9606 | 21779440 | ||||
| IKBKB | IKBKB | down-regulates | phosphorylation | 9606 | 10195894 | ||||
| MAPK1 | TFEB | down-regulates | phosphorylation | 9606 | 21617040 | ||||
| STK11 | PTEN | down-regulates | phosphorylation | 9606 | 18321849 | ||||
| MAPK1 | STK11 | down-regulates | phosphorylation | 9606 | 25846811 | ||||
| PTEN | AKT1 | down-regulates | 9606 | 20596030 | |||||
| PTEN | RPS6KB1 | down-regulates | dephosphorylation | 9606 | 19436944 | ||||
| IKBKB | IKBKB | down-regulates | phosphorylation | 9606 | 10195894 | ||||
| STK11 | PTEN | down-regulates | phosphorylation | 9606 | 21779440 | ||||
| MAPK1 | SMAD3 | down-regulates | phosphorylation | 9606 | 19914161 | ||||
| IKBKB | IKBKB | down-regulates | phosphorylation | 9606 | 10195894 | ||||
| SRC | CTNNB1 | down-regulates | phosphorylation | 9606 | 11279024 | ||||
| IKBKB | IKBKB | down-regulates | phosphorylation | 9606 | 10195894 | ||||
| MAPK1 | SMAD3 | down-regulates | phosphorylation | 9606 | 10197981 | ||||
| PTEN | SRC | down-regulates | dephosphorylation | 9606 | 22482061 | ||||
| HES1 | NR3C1 | down-regulates | 9606 | 24300895 | |||||
| IKBKB | IKBKB | down-regulates | phosphorylation | 9606 | 10195894 | ||||
| JUN | SMAD3 | down-regulates | binding | 9606 | 10871633 | ||||
| DUSP1 | JUN | down-regulates | dephosphorylation | 9606 | 26734995 | ||||
| SRC | RHOA | down-regulates | phosphorylation | 9606 | 23027962 | ||||
| FBP1 | HIF1A | down-regulates | binding | 9606 | 30616754 | ||||
| IKBKB | IKBKB | down-regulates | phosphorylation | 9606 | 10195894 | ||||
| STK11 | STK11 | down-regulates | phosphorylation | 9606 | 11430832 | ||||
| IKBKB | IKBKB | down-regulates | phosphorylation | 9606 | 10195894 | ||||
| SRC | SRC | down-regulates | phosphorylation | 9606 | 8755732 | ||||
| PTPN13 | SRC | down-regulates | dephosphorylation | 9606 | 19307596 | ||||
| AKT1 | PPARGC1A | down-regulates | phosphorylation | 9606 | 17554339 | ||||
| IKBKB | IKBKB | down-regulates | phosphorylation | 9606 | 10195894 | ||||
| IKBKB | IKBKB | down-regulates | phosphorylation | 9606 | 10195894 | ||||
| IKBKB | IKBKB | down-regulates | phosphorylation | 9606 | 10195894 | ||||
| PTEN | SP1 | down-regulates | dephosphorylation | 9606 | 21603612 | ||||
| EGFR | ABCA1 | down-regulates | phosphorylation | 9606 | 12196520 | ||||
| MAPK1 | CDKN1A | down-regulates | phosphorylation | 9606 | 19364816 | ||||
| MYLIP | VLDLR | down-regulates | ubiquitination | 9606 | 20427281 | ||||
| EP300 | PCK1 | down-regulates | acetylation | 9606 | 21726808 | ||||
| CLU | IKBKB | down-regulates | binding | 9606 | 20068069 | ||||
| EP300 | PCK1 | down-regulates | acetylation | 9606 | 21726808 | ||||
| PRKCZ | CTNNB1 | down-regulates | phosphorylation | 9606 | 25660024 | ||||
| MYLIP | LDLR | down-regulates | ubiquitination | 9606 | 30896554 | ||||
| PRKCZ | CTNNB1 | down-regulates | phosphorylation | 9606 | 25660024 | ||||
| PRKCZ | YAP1 | down-regulates | phosphorylation | 9606 | 25660024 | ||||
| EP300 | PCK1 | down-regulates | acetylation | 9606 | 21726808 | ||||
| PRKCZ | CTNNB1 | down-regulates | phosphorylation | 9606 | 25660024 | ||||
| PRKCZ | YAP1 | down-regulates | phosphorylation | 9606 | 25660024 | ||||
| AKT1 | FOXO1 | down-regulates | phosphorylation | 9606 | 21440011 | ||||
| MAPK1 | CDKN1A | down-regulates | phosphorylation | 9606 | 19364816 | ||||
| PDLIM2 | RELA | down-regulates | polyubiquitination | 9606 | 17468759 | ||||
| SOX6 | CTNNB1 | down-regulates | binding | 9606 | 26893351 | ||||
| EGR1 | FAS | down-regulates | transcriptional regulation | 9606 | 9300687 | ||||
| NR3C1 | JUN | down-regulates | transcriptional regulation | 9606 | 8639160 | ||||
| RELA | BMP4 | down-regulates | transcriptional regulation | 9606 | 17350185 | ||||
| PRKAA1 | CDKN1A | down-regulates | transcriptional regulation | 9606 | 19491292 | ||||
| HDAC1 | DNMT1 | down-regulates | transcriptional regulation | 9606 | 23242655 | ||||
| HES1 | NR3C1 | down-regulates | transcriptional regulation | 9606 | 19129776 | ||||
| NFE2L2 | GSTA1 | down-regulates | transcriptional regulation | 9606 | 22459801 | ||||
| HDAC1 | EGR1 | down-regulates | transcriptional regulation | 9606 | 21983014 | ||||
| NR3C1 | ATP1B1 | down-regulates | transcriptional regulation | 9606 | 9694812 | ||||
| DNMT1 | ESR1 | down-regulates | transcriptional regulation | 9606 | 23242655 | ||||
| HDAC1 | ESR1 | down-regulates | transcriptional regulation | 9606 | 23242655 | ||||
| SRC | PROM1 | unknown | phosphorylation | 9606 | 19296573 | ||||
| SRC | PROM1 | unknown | phosphorylation | 9606 | 19296573 | ||||
| STK11 | PTEN | unknown | phosphorylation | 9606 | 15987703 | ||||
| MAPK1 | SMAD3 | unknown | phosphorylation | 9606 | 15241418 | ||||
| MAPK1 | SMAD3 | unknown | phosphorylation | 9606 | 19914168 | ||||
| MAPK1 | SMAD3 | unknown | phosphorylation | 9606 | 15241418 | ||||
| SRC | KRT19 | unknown | phosphorylation | 9606 | 21049038 | ||||
| PRKAA1 | FOXO1 | up-regulates | phosphorylation | 9606 | 17900900 | ||||
| EGFR | STAT1 | up-regulates | phosphorylation | 9606 | 22693070 | ||||
| PRKCZ | SP1 | up-regulates | phosphorylation | 9606 | 18258854 | ||||
| MAPK1 | ESR1 | up-regulates | phosphorylation | 9606 | 18372406 | ||||
| EGF | EGFR | up-regulates | binding | 9606 | 12648462 | ||||
| SRC | SRC | up-regulates | phosphorylation | 9606 | 7578094 | ||||
| EGFR | STAT5A | up-regulates | binding | 9606 | 10358079 | ||||
| EGFR | STAT1 | up-regulates | phosphorylation | 9606 | 14967450 | ||||
| SRC | STAT5A | up-regulates | phosphorylation | 9606 | 11641791 | ||||
| MAPK1 | SP1 | up-regulates | phosphorylation | 9606 | 11904305 | ||||
| MAPK1 | DUSP1 | up-regulates | phosphorylation | 9606 | 10617468 | ||||
| AKT1 | ESR1 | up-regulates | phosphorylation | 9606 | 11108261 | ||||
| MAPK1 | ESR1 | up-regulates | phosphorylation | 9606 | 18372406 | ||||
| SRC | ESR1 | up-regulates | phosphorylation | 9606 | 9500442 | ||||
| MAPK1 | SP1 | up-regulates | phosphorylation | 9606 | 19318349 | ||||
| EGFR | ESR1 | up-regulates | phosphorylation | 9606 | 11887937 | ||||
| MAPK1 | RPS6KB1 | up-regulates | phosphorylation | 9606 | 14967450 | ||||
| MAPK1 | ESR1 | up-regulates | phosphorylation | 9606 | 12466266 | ||||
| MAPK1 | RPS6KB1 | up-regulates | phosphorylation | 9606 | 19085255 | ||||
| MAPK1 | PRDX6 | up-regulates | phosphorylation | 9606 | 19140803 | ||||
| PRKCZ | SP1 | up-regulates | phosphorylation | 9606 | 16943418 | ||||
| MAPK1 | SMAD4 | up-regulates | phosphorylation | 9606 | 12801888 | ||||
| MAPK1 | SMAD2 | up-regulates | phosphorylation | 9606 | 12193595 | ||||
| MAPK1 | RPS6KB1 | up-regulates | phosphorylation | 9606 | 21035469 | ||||
| AKT1 | ESR1 | up-regulates | phosphorylation | 9606 | 11108261 | ||||
| MAPK1 | EP300 | up-regulates | phosphorylation | 9606 | 17623675 | ||||
| EP300 | DUSP1 | up-regulates | acetylation | 9606 | 20626350 | ||||
| ILK | AKT1 | up-regulates | phosphorylation | 9606 | 9736715 | ||||
| PRKCZ | RELA | up-regulates | phosphorylation | 9606 | 17183360 | ||||
| MAPK1 | SMAD2 | up-regulates | phosphorylation | 9606 | 12193595 | ||||
| MAPK1 | SP1 | up-regulates | phosphorylation | 9606 | 11904305 | ||||
| HDAC1 | CCND1 | up-regulates | binding | 9606 | 15713663 | ||||
| MAPK1 | ESR1 | up-regulates | phosphorylation | 9606 | 17615152 | ||||
| SRC | IKBKB | up-regulates | phosphorylation | 9606 | 12645577 | ||||
| ROCK2 | DPYSL2 | up-regulates | phosphorylation | 9606 | 10818093 | ||||
| MAPK1 | SP1 | up-regulates | phosphorylation | 9606 | 11904305 | ||||
| MAPK1 | HIF1A | up-regulates | phosphorylation | 9606 | 18519666 | ||||
| PYCARD | BAX | up-regulates | relocalization | 9606 | 16964285 | ||||
| MAPK1 | DUSP1 | up-regulates | phosphorylation | 9606 | 10617468 | ||||
| SRC | ENO1 | up-regulates | phosphorylation | 9606 | 7629021 | ||||
| MAPK1 | SMAD2 | up-regulates | phosphorylation | 9606 | 12193595 | ||||
| AKT1 | ESR1 | up-regulates | phosphorylation | 9606 | 11108261 | ||||
| MAPK1 | EP300 | up-regulates | phosphorylation | 9606 | 17623675 | ||||
| PRKCZ | SP1 | up-regulates | phosphorylation | 9606 | 18258854 | ||||
| MAPK1 | STAT5A | up-regulates | phosphorylation | 9606 | 10194762 | ||||
| SRC | EGFR | up-regulates | phosphorylation | 9606 | 8845374 | ||||
| CTNNB1 | EP300 | up-regulates | binding | 9606 | 10775268 | ||||
| CCND1 | NOTCH1 | up-regulates | 9606 | 20443831 | |||||
| YAP1 | CTNNB1 | up-regulates | binding | 9606 | 23607968 | ||||
| AKT1 | DNMT1 | up-regulates | phosphorylation | 9606 | 21151116 | ||||
| EGFR | STAT5A | up-regulates | binding | 9606 | 16729043 | ||||
| SRC | IKBKB | up-regulates | phosphorylation | 9606 | 12645577 | ||||
| MAPK1 | RPS6KB1 | up-regulates | phosphorylation | 9606 | 11705993 | ||||
| RELA | SP1 | up-regulates | binding | 9606 | 10671503 | ||||
| PRKCZ | SP1 | up-regulates | phosphorylation | 9606 | 19464346 | ||||
| EGFR | PCNA | up-regulates | phosphorylation | 9606 | 17115032 | ||||
| MAPK1 | HIF1A | up-regulates | phosphorylation | 9606 | 18519666 | ||||
| MAPK1 | RPS6KB1 | up-regulates | phosphorylation | 9606 | 19085255 | ||||
| ERN1 | JUN | up-regulates | 9606 | 18065414 | |||||
| MAPK1 | RPS6KB1 | up-regulates | phosphorylation | 9606 | 15774499 | ||||
| SRC | CTNNB1 | up-regulates | phosphorylation | 9606 | 22056988 | ||||
| PIK3C3 | AKT1 | up-regulates | 9606 | 10698680 | |||||
| MAPK1 | ESR1 | up-regulates | phosphorylation | 9606 | 17615152 | ||||
| AKT1 | EP300 | up-regulates | phosphorylation | 9606 | 17964260 | ||||
| MAPK1 | ESR1 | up-regulates | phosphorylation | 9606 | 17615152 | ||||
| PRKCZ | SP1 | up-regulates | phosphorylation | 9606 | 18258854 | ||||
| MAPK1 | RPS6KB1 | up-regulates | phosphorylation | 9606 | 7545671 | ||||
| RELA | EGR1 | up-regulates | binding | 9606 | 10671503 | ||||
| MAPK1 | SMAD2 | up-regulates | phosphorylation | 9606 | 12193595 | ||||
| PIK3C3 | PTEN | up-regulates | binding | 9606 | 20212113 | ||||
| BMP4 | BMP4 | up-regulates | binding | 9606 | 11178121 | ||||
| MAPK1 | EP300 | up-regulates | phosphorylation | 9606 | 17623675 | ||||
| MAPK1 | RPS6KB1 | up-regulates | phosphorylation | 9606 | 21035469 | ||||
| JAK1 | STAT1 | up-regulates | phosphorylation | 9606 | 21576360 | ||||
| SRC | SRC | up-regulates | phosphorylation | 9606 | 12753909 | ||||
| EIF2AK3 | EIF2AK3 | up-regulates | phosphorylation | 9606 | 17998206 | ||||
| RPS6KB1 | ESR1 | up-regulates | phosphorylation | 9606 | 7838153 |
