Selected Cell
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PathwayEnrichmentResults_Top30
PathwayNetwork_Top30
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| id | geneSet | link | size | overlap | expect | enrichmentRatio | pValue | FDR | gene_count | genes |
| Activated NTRK2 signals through FYN | R-HSA-9032500 | http://reactome.org/PathwayBrowser/#/R-HSA-9032500 | 7 | 2 | 0.0689851227139202 | 28.9917582417582 | 0.0019559593949394 | 0.0165915958625458 | 2 | RAC1;SRC |
| Activated NTRK3 signals through PI3K | R-HSA-9603381 | http://reactome.org/PathwayBrowser/#/R-HSA-9603381 | 6 | 3 | 0.0591301051833601 | 50.7355769230769 | 1.82016872645185E-5 | 4.49766330231943E-4 | 3 | IRS1;PIK3R1;SRC |
| Activation of caspases through apoptosome-mediated cleavage | R-HSA-111459 | http://reactome.org/PathwayBrowser/#/R-HSA-111459 | 5 | 3 | 0.0492750876528001 | 60.8826923076923 | 9.1666071717622E-6 | 2.84164822324628E-4 | 3 | APAF1;CASP3;CASP9 |
| Activation of the AP-1 family of transcription factors | R-HSA-450341 | http://reactome.org/PathwayBrowser/#/R-HSA-450341 | 10 | 3 | 0.0985501753056003 | 30.4413461538461 | 1.06112826487647E-4 | 0.0016299312537066 | 3 | FOS;JUN;MAPK1 |
| Apoptotic cleavage of cell adhesion proteins | R-HSA-351906 | http://reactome.org/PathwayBrowser/#/R-HSA-351906 | 11 | 3 | 0.10840519283616 | 27.673951048951 | 1.44860525323808E-4 | 0.0021291999627335 | 3 | CASP3;CDH1;CTNNB1 |
| CLEC7A/inflammasome pathway | R-HSA-5660668 | http://reactome.org/PathwayBrowser/#/R-HSA-5660668 | 6 | 2 | 0.0591301051833601 | 33.8237179487179 | 0.0014061494321098 | 0.0131729933063034 | 2 | PYCARD;RELA |
| Erythropoietin activates Phosphoinositide-3-kinase (PI3K) | R-HSA-9027276 | http://reactome.org/PathwayBrowser/#/R-HSA-9027276 | 11 | 3 | 0.10840519283616 | 27.673951048951 | 1.44860525323808E-4 | 0.0021291999627335 | 3 | IRS2;JAK2;PIK3R1 |
| Erythropoietin activates Phospholipase C gamma (PLCG) | R-HSA-9027277 | http://reactome.org/PathwayBrowser/#/R-HSA-9027277 | 6 | 2 | 0.0591301051833601 | 33.8237179487179 | 0.0014061494321098 | 0.0131729933063034 | 2 | IRS2;JAK2 |
| Erythropoietin activates STAT5 | R-HSA-9027283 | http://reactome.org/PathwayBrowser/#/R-HSA-9027283 | 6 | 3 | 0.0591301051833601 | 50.7355769230769 | 1.82016872645185E-5 | 4.49766330231943E-4 | 3 | IRS2;JAK2;STAT5A |
| GAB1 signalosome | R-HSA-180292 | http://reactome.org/PathwayBrowser/#/R-HSA-180292 | 11 | 3 | 0.10840519283616 | 27.673951048951 | 1.44860525323808E-4 | 0.0021291999627335 | 3 | EGFR;PIK3R1;SRC |
| GP1b-IX-V activation signalling | R-HSA-430116 | http://reactome.org/PathwayBrowser/#/R-HSA-430116 | 12 | 3 | 0.11826021036672 | 25.3677884615384 | 1.91765097079521E-4 | 0.0026799958239392 | 3 | COL1A2;PIK3R1;SRC |
| Growth hormone receptor signaling | R-HSA-982772 | http://reactome.org/PathwayBrowser/#/R-HSA-982772 | 24 | 8 | 0.23652042073344 | 33.8237179487179 | 4.37203606651337E-11 | 1.49086429868106E-8 | 8 | IRS1;IRS2;JAK2;MAPK1;PTPN6;SOCS1;STAT1;STAT5A |
| IRS activation | R-HSA-74713 | http://reactome.org/PathwayBrowser/#/R-HSA-74713 | 5 | 3 | 0.0492750876528001 | 60.8826923076923 | 9.1666071717622E-6 | 2.84164822324628E-4 | 3 | INSR;IRS1;IRS2 |
| IkBA variant leads to EDA-ID | R-HSA-5603029 | http://reactome.org/PathwayBrowser/#/R-HSA-5603029 | 7 | 2 | 0.0689851227139202 | 28.9917582417582 | 0.0019559593949394 | 0.0165915958625458 | 2 | NFKB2;RELA |
| Inflammasomes | R-HSA-622312 | http://reactome.org/PathwayBrowser/#/R-HSA-622312 | 20 | 5 | 0.1971003506112 | 25.3677884615384 | 1.1632368943637E-6 | 4.72218786878599E-5 | 5 | BCL2;NFKB2;PYCARD;RELA;TXN |
| InlA-mediated entry of Listeria monocytogenes into host cells | R-HSA-8876493 | http://reactome.org/PathwayBrowser/#/R-HSA-8876493 | 9 | 4 | 0.0886951577750402 | 45.0982905982906 | 1.07989954878373E-6 | 4.49080178213724E-5 | 4 | CDH1;CTNNB1;SRC;UBC |
| Loss of Function of SMAD2/3 in Cancer | R-HSA-3304349 | http://reactome.org/PathwayBrowser/#/R-HSA-3304349 | 7 | 3 | 0.0689851227139202 | 43.4876373626373 | 3.16245250359115E-5 | 6.57558721783282E-4 | 3 | SMAD2;SMAD4;TGFB1 |
| PI3K/AKT activation | R-HSA-198203 | http://reactome.org/PathwayBrowser/#/R-HSA-198203 | 9 | 3 | 0.0886951577750402 | 33.8237179487179 | 7.48148384522862E-5 | 0.0012983536094508 | 3 | IRS1;IRS2;PIK3R1 |
| PTK6 Expression | R-HSA-8849473 | http://reactome.org/PathwayBrowser/#/R-HSA-8849473 | 5 | 2 | 0.0492750876528001 | 40.5884615384615 | 9.4350018382805E-4 | 0.0096327413977654 | 2 | HIF1A;NR3C1 |
| PTK6 promotes HIF1A stabilization | R-HSA-8857538 | http://reactome.org/PathwayBrowser/#/R-HSA-8857538 | 6 | 2 | 0.0591301051833601 | 33.8237179487179 | 0.0014061494321098 | 0.0131729933063034 | 2 | EGFR;HIF1A |
| RSK activation | R-HSA-444257 | http://reactome.org/PathwayBrowser/#/R-HSA-444257 | 6 | 3 | 0.0591301051833601 | 50.7355769230769 | 1.82016872645185E-5 | 4.49766330231943E-4 | 3 | MAPK1;PDPK1;RPS6KA3 |
| RUNX3 regulates CDKN1A transcription | R-HSA-8941855 | http://reactome.org/PathwayBrowser/#/R-HSA-8941855 | 7 | 4 | 0.0689851227139202 | 57.9835164835164 | 3.04570236142609E-7 | 1.62278828944734E-5 | 4 | CDKN1A;SMAD4;TGFB1;TP53 |
| Regulation of IFNG signaling | R-HSA-877312 | http://reactome.org/PathwayBrowser/#/R-HSA-877312 | 14 | 4 | 0.13797024542784 | 28.9917582417582 | 8.25932369319382E-6 | 2.72265634228573E-4 | 4 | JAK2;PTPN6;SOCS1;STAT1 |
| SMAC binds to IAPs | R-HSA-111463 | http://reactome.org/PathwayBrowser/#/R-HSA-111463 | 5 | 2 | 0.0492750876528001 | 40.5884615384615 | 9.4350018382805E-4 | 0.0096327413977654 | 2 | CASP3;CASP9 |
| SMAD2/3 Phosphorylation Motif Mutants in Cancer | R-HSA-3304356 | http://reactome.org/PathwayBrowser/#/R-HSA-3304356 | 6 | 2 | 0.0591301051833601 | 33.8237179487179 | 0.0014061494321098 | 0.0131729933063034 | 2 | SMAD2;TGFB1 |
| SOS-mediated signalling | R-HSA-112412 | http://reactome.org/PathwayBrowser/#/R-HSA-112412 | 7 | 2 | 0.0689851227139202 | 28.9917582417582 | 0.0019559593949394 | 0.0165915958625458 | 2 | IRS1;IRS2 |
| Sema4D mediated inhibition of cell attachment and migration | R-HSA-416550 | http://reactome.org/PathwayBrowser/#/R-HSA-416550 | 8 | 2 | 0.0788401402444802 | 25.3677884615384 | 0.0025912003514243 | 0.0209022460597663 | 2 | RAC1;RRAS |
| Signal attenuation | R-HSA-74749 | http://reactome.org/PathwayBrowser/#/R-HSA-74749 | 10 | 4 | 0.0985501753056003 | 40.5884615384615 | 1.78619970325755E-6 | 7.0824895210561E-5 | 4 | INSR;IRS1;IRS2;MAPK1 |
| Signaling by Leptin | R-HSA-2586552 | http://reactome.org/PathwayBrowser/#/R-HSA-2586552 | 11 | 4 | 0.10840519283616 | 36.8986013986014 | 2.78562959099559E-6 | 1.07943146651079E-4 | 4 | IRS1;IRS2;JAK2;STAT5A |
| The NLRP3 inflammasome | R-HSA-844456 | http://reactome.org/PathwayBrowser/#/R-HSA-844456 | 15 | 4 | 0.1478252629584 | 27.0589743589743 | 1.11775086250043E-5 | 3.12420527961186E-4 | 4 | NFKB2;PYCARD;RELA;TXN |
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| Note: Edges are drawn between pathways based on their common genes, and the edge width is based on the number of those genes. | |||||||||
