Selected Cell
Cell:
Value:
stat_data__min_2_Peptides
Sheet1
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B
C
D
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G
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I
J
K
L
4601
4602
4603
4604
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4800
| P58004 | P58004 | SESN2_HUMAN | Sestrin-2 (EC 1.11.1.-) (Hypoxia-induced gene) | SESN2 | cellular oxidant detoxification [GO:0098869]; cellular response to amino acid starvation [GO:0034198]; cellular response to amino acid stimulus [GO:0071230]; cellular response to glucose starvation [GO:0042149]; cellular response to leucine [GO:0071233]; cellular response to leucine starvation [GO:1990253]; cellular response to oxidative stress [GO:0034599]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; fatty acid beta-oxidation [GO:0006635]; glucose homeostasis [GO:0042593]; glucose import [GO:0046323]; mitochondrial DNA metabolic process [GO:0032042]; negative regulation of cell growth [GO:0030308]; negative regulation of TORC1 signaling [GO:1904262]; negative regulation of translation in response to endoplasmic reticulum stress [GO:1902010]; positive regulation of lipophagy [GO:1904504]; positive regulation of macroautophagy [GO:0016239]; positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of TORC1 signaling [GO:1904263]; reactive oxygen species metabolic process [GO:0072593]; regulation of gluconeogenesis [GO:0006111]; regulation of protein phosphorylation [GO:0001932]; regulation of response to reactive oxygen species [GO:1901031]; regulation of TORC1 signaling [GO:1903432]; response to glucose [GO:0009749]; response to insulin [GO:0032868]; triglyceride homeostasis [GO:0070328] | Atg1/ULK1 kinase complex [GO:1990316]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; lysosomal membrane [GO:0005765]; mitochondrion [GO:0005739]; nucleotide-activated protein kinase complex [GO:0031588]; nucleus [GO:0005634]; TORC2 complex [GO:0031932] | GDP-dissociation inhibitor activity [GO:0005092]; leucine binding [GO:0070728]; oxidoreductase activity, acting on peroxide as acceptor [GO:0016684]; peroxidase activity [GO:0004601]; PH domain binding [GO:0042731]; protein sequestering activity [GO:0140311]; protein-containing complex binding [GO:0044877]; sulfiredoxin activity [GO:0032542] | 4501.287770173205 | -0.0870659167931913 | 0.935131824839242 | 1 |
| Q86VW0 | Q86VW0 | SESD1_HUMAN | SEC14 domain and spectrin repeat-containing protein 1 (Huntingtin-interacting protein-like protein) (Protein Solo) | SESTD1 | negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel [GO:1904878] | intermediate filament cytoskeleton [GO:0045111] | phosphatidic acid binding [GO:0070300]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; phosphatidylinositol-3,5-bisphosphate binding [GO:0080025]; phosphatidylinositol-3-phosphate binding [GO:0032266]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylinositol-4-phosphate binding [GO:0070273]; phosphatidylinositol-5-phosphate binding [GO:0010314] | 5205.82175452502 | -0.246340780578412 | 0.796335667662129 | 1 |
| Q8WTS6 | Q8WTS6 | SETD7_HUMAN | Histone-lysine N-methyltransferase SETD7 (EC 2.1.1.364) (Histone H3-K4 methyltransferase SETD7) (H3-K4-HMTase SETD7) (Lysine N-methyltransferase 7) (SET domain-containing protein 7) (SET7/9) | SETD7 | chromatin organization [GO:0006325]; DNA damage response [GO:0006974]; heterochromatin organization [GO:0070828]; peptidyl-lysine dimethylation [GO:0018027]; peptidyl-lysine monomethylation [GO:0018026]; positive regulation of DNA-templated transcription [GO:0045893]; response to ethanol [GO:0045471] | chromosome [GO:0005694]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] | chromatin binding [GO:0003682]; histone H3 methyltransferase activity [GO:0140938]; histone H3K4 monomethyltransferase activity [GO:0140945]; histone methyltransferase activity [GO:0042054]; p53 binding [GO:0002039]; protein-lysine N-methyltransferase activity [GO:0016279] | 17255.2597139349 | 0.079172913519329 | 0.890209944117026 | 1 |
| Q15637 | Q15637 | SF01_HUMAN | Splicing factor 1 (Mammalian branch point-binding protein) (BBP) (mBBP) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Zinc finger protein 162) | SF1 | Leydig cell differentiation [GO:0033327]; male sex determination [GO:0030238]; mRNA 3'-splice site recognition [GO:0000389]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of smooth muscle cell proliferation [GO:0048662]; nuclear body organization [GO:0030575]; regulation of mRNA splicing, via spliceosome [GO:0048024]; regulation of steroid biosynthetic process [GO:0050810]; spliceosomal complex assembly [GO:0000245] | nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribosome [GO:0005840]; spliceosomal complex [GO:0005681]; U2AF complex [GO:0089701] | identical protein binding [GO:0042802]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; transcription corepressor activity [GO:0003714]; zinc ion binding [GO:0008270] | 34839.5694487225 | 0.0616965086820933 | 0.981620925626116 | 1 |
| Q15459 | Q15459 | SF3A1_HUMAN | Splicing factor 3A subunit 1 (SF3a120) (Spliceosome-associated protein 114) (SAP 114) | SF3A1 | mRNA 3'-splice site recognition [GO:0000389]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; U2-type prespliceosome assembly [GO:1903241] | catalytic step 2 spliceosome [GO:0071013]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spliceosomal complex [GO:0005681]; U2 snRNP [GO:0005686]; U2-type precatalytic spliceosome [GO:0071005]; U2-type prespliceosome [GO:0071004]; U2-type spliceosomal complex [GO:0005684] | RNA binding [GO:0003723] | 29086.954795463 | 0.0279739162272984 | 0.999997294151427 | 1 |
| Q15428 | Q15428 | SF3A2_HUMAN | Splicing factor 3A subunit 2 (SF3a66) (Spliceosome-associated protein 62) (SAP 62) | SF3A2 | mRNA 3'-splice site recognition [GO:0000389]; mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of neuron projection development [GO:0010976]; spliceosomal complex assembly [GO:0000245]; U2-type prespliceosome assembly [GO:1903241] | catalytic step 2 spliceosome [GO:0071013]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spliceosomal complex [GO:0005681]; U2 snRNP [GO:0005686]; U2-type precatalytic spliceosome [GO:0071005]; U2-type prespliceosome [GO:0071004]; U2-type spliceosomal complex [GO:0005684] | RNA binding [GO:0003723]; zinc ion binding [GO:0008270] | 13681.0940629493 | 0.0620085915338976 | 0.967852364467367 | 1 |
| Q12874 | Q12874 | SF3A3_HUMAN | Splicing factor 3A subunit 3 (SF3a60) (Spliceosome-associated protein 61) (SAP 61) | SF3A3 | mRNA 3'-splice site recognition [GO:0000389]; mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; RNA splicing, via transesterification reactions [GO:0000375]; U2-type prespliceosome assembly [GO:1903241] | catalytic step 2 spliceosome [GO:0071013]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spliceosomal complex [GO:0005681]; U2 snRNP [GO:0005686]; U2-type precatalytic spliceosome [GO:0071005]; U2-type spliceosomal complex [GO:0005684] | RNA binding [GO:0003723]; zinc ion binding [GO:0008270] | 14900.664745307451 | 0.0357535875190957 | 0.998662285665981 | 1 |
| O75533 | O75533 | SF3B1_HUMAN | Splicing factor 3B subunit 1 (Pre-mRNA-splicing factor SF3b 155 kDa subunit) (SF3b155) (Spliceosome-associated protein 155) (SAP 155) | SF3B1 | chromatin remodeling [GO:0006338]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription by RNA polymerase III [GO:0045945]; RNA splicing [GO:0008380]; RNA splicing, via transesterification reactions [GO:0000375]; spliceosomal complex assembly [GO:0000245]; U2-type prespliceosome assembly [GO:1903241] | B-WICH complex [GO:0110016]; catalytic step 2 spliceosome [GO:0071013]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spliceosomal complex [GO:0005681]; U11/U12 snRNP [GO:0034693]; U12-type spliceosomal complex [GO:0005689]; U2 snRNP [GO:0005686]; U2-type precatalytic spliceosome [GO:0071005]; U2-type prespliceosome [GO:0071004]; U2-type spliceosomal complex [GO:0005684] | mRNA binding [GO:0003729]; RNA binding [GO:0003723]; splicing factor binding [GO:1990935] | 12827.73351601795 | -0.148563782359632 | 0.770362210144848 | 1 |
| Q13435 | Q13435 | SF3B2_HUMAN | Splicing factor 3B subunit 2 (Pre-mRNA-splicing factor SF3b 145 kDa subunit) (SF3b145) (Spliceosome-associated protein 145) (SAP 145) | SF3B2 | mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; RNA splicing [GO:0008380]; U2-type prespliceosome assembly [GO:1903241] | catalytic step 2 spliceosome [GO:0071013]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; precatalytic spliceosome [GO:0071011]; spliceosomal complex [GO:0005681]; U12-type spliceosomal complex [GO:0005689]; U2 snRNP [GO:0005686]; U2-type precatalytic spliceosome [GO:0071005]; U2-type spliceosomal complex [GO:0005684] | RNA binding [GO:0003723] | 26489.1945679235 | 0.046779579939426 | 0.998624811168854 | 1 |
| Q9Y3B4 | Q9Y3B4 | SF3B6_HUMAN | Splicing factor 3B subunit 6 (Pre-mRNA branch site protein p14) (SF3b 14 kDa subunit) (SF3B14a) (Spliceosome-associated protein, 14-kDa) (Splicing factor 3b, subunit 6, 14kDa) | SF3B6 | blastocyst formation [GO:0001825]; mRNA splicing, via spliceosome [GO:0000398]; U2-type prespliceosome assembly [GO:1903241] | catalytic step 2 spliceosome [GO:0071013]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; precatalytic spliceosome [GO:0071011]; spliceosomal complex [GO:0005681]; U12-type spliceosomal complex [GO:0005689]; U2 snRNP [GO:0005686]; U2-type spliceosomal complex [GO:0005684] | mRNA binding [GO:0003729]; RNA binding [GO:0003723] | 25821.335449053448 | -0.101291436869348 | 0.718559502194664 | 1 |
| P23246 | P23246 | SFPQ_HUMAN | Splicing factor, proline- and glutamine-rich (100 kDa DNA-pairing protein) (hPOMp100) (DNA-binding p52/p100 complex, 100 kDa subunit) (Polypyrimidine tract-binding protein-associated-splicing factor) (PSF) (PTB-associated-splicing factor) | SFPQ | activation of innate immune response [GO:0002218]; alternative mRNA splicing, via spliceosome [GO:0000380]; chromatin remodeling [GO:0006338]; double-strand break repair via homologous recombination [GO:0000724]; innate immune response [GO:0045087]; mRNA processing [GO:0006397]; negative regulation of circadian rhythm [GO:0042754]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of circadian rhythm [GO:0042752]; regulation of DNA-templated transcription [GO:0006355]; rhythmic process [GO:0048511]; RNA splicing [GO:0008380] | chromatin [GO:0000785]; cytosol [GO:0005829]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; paraspeckles [GO:0042382]; RNA polymerase II transcription regulator complex [GO:0090575] | chromatin binding [GO:0003682]; DNA binding [GO:0003677]; histone deacetylase binding [GO:0042826]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; transcription cis-regulatory region binding [GO:0000976] | 70832.34097280765 | 0.0373072821176075 | 0.999998555691161 | 1 |
| Q9P0V3 | Q9P0V3 | SH3B4_HUMAN | SH3 domain-binding protein 4 (EH-binding protein 10) (Transferrin receptor-trafficking protein) | SH3BP4 | cellular response to amino acid stimulus [GO:0071230]; endocytosis [GO:0006897]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of GTPase activity [GO:0034260]; negative regulation of TOR signaling [GO:0032007]; positive regulation of autophagy [GO:0010508]; protein localization to lysosome [GO:0061462]; regulation of catalytic activity [GO:0050790] | clathrin-coated pit [GO:0005905]; clathrin-coated vesicle [GO:0030136]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; nucleus [GO:0005634] | GDP-dissociation inhibitor activity [GO:0005092]; identical protein binding [GO:0042802]; small GTPase binding [GO:0031267] | 6613.066272278826 | 0.0473834262119494 | 0.977187130035201 | 1 |
| Q7L8J4 | Q7L8J4 | 3BP5L_HUMAN | SH3 domain-binding protein 5-like (SH3BP-5-like) | SH3BP5L | intracellular signal transduction [GO:0035556] | cytoplasm [GO:0005737] | guanyl-nucleotide exchange factor activity [GO:0005085]; protein kinase inhibitor activity [GO:0004860] | 3820.61780690527 | -0.254685041256426 | 0.72487755785664 | 1 |
| Q96B97 | Q96B97 | SH3K1_HUMAN | SH3 domain-containing kinase-binding protein 1 (CD2-binding protein 3) (CD2BP3) (Cbl-interacting protein of 85 kDa) (Human Src family kinase-binding protein 1) (HSB-1) | SH3KBP1 | actin filament organization [GO:0007015]; apoptotic process [GO:0006915]; cell migration [GO:0016477]; cell-cell signaling [GO:0007267]; cytoskeleton organization [GO:0007010]; endocytosis [GO:0006897]; positive regulation of B cell activation [GO:0050871]; regulation of cell shape [GO:0008360] | cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic vesicle membrane [GO:0030659]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; endocytic vesicle [GO:0030139]; focal adhesion [GO:0005925]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; synapse [GO:0045202] | SH3 domain binding [GO:0017124]; ubiquitin protein ligase binding [GO:0031625] | 17356.55297091225 | -0.0537167981450211 | 0.997422279326443 | 1 |
| Q7Z6J0 | Q7Z6J0 | SH3R1_HUMAN | E3 ubiquitin-protein ligase SH3RF1 (EC 2.3.2.27) (Plenty of SH3s) (Protein POSH) (RING finger protein 142) (RING-type E3 ubiquitin transferase SH3RF1) (SH3 domain-containing RING finger protein 1) (SH3 multiple domains protein 2) | SH3RF1 | negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; neuron migration [GO:0001764]; positive regulation of JNK cascade [GO:0046330]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein autoubiquitination [GO:0051865]; protein ubiquitination [GO:0016567]; regulation of CD4-positive, alpha-beta T cell differentiation [GO:0043370]; regulation of CD8-positive, alpha-beta T cell proliferation [GO:2000564]; response to aldosterone [GO:1904044] | cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; lamellipodium [GO:0030027]; perinuclear region of cytoplasm [GO:0048471] | MAP-kinase scaffold activity [GO:0005078]; metal ion binding [GO:0046872]; ubiquitin protein ligase activity [GO:0061630] | 4080.0421026432196 | -0.0827073173559268 | 0.992188276292448 | 1 |
| Q9UQ13 | Q9UQ13 | SHOC2_HUMAN | Leucine-rich repeat protein SHOC-2 (Protein soc-2 homolog) (Protein sur-8 homolog) | SHOC2 | cellular response to growth hormone stimulus [GO:0071378]; cyclic-GMP-AMP transmembrane import across plasma membrane [GO:0140361]; fibroblast growth factor receptor signaling pathway [GO:0008543]; negative regulation of neural precursor cell proliferation [GO:2000178]; negative regulation of neuron differentiation [GO:0045665]; nerve growth factor signaling pathway [GO:0038180]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of neuron projection development [GO:0010976]; positive regulation of Ras protein signal transduction [GO:0046579]; Ras protein signal transduction [GO:0007265]; signal transduction [GO:0007165] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein phosphatase type 1 complex [GO:0000164] | protein phosphatase 1 binding [GO:0008157]; protein phosphatase binding [GO:0019903]; protein phosphatase regulator activity [GO:0019888] | 6271.204115622585 | -0.0980154648447157 | 0.840809106222772 | 1 |
| Q9UHJ6 | Q9UHJ6 | SHPK_HUMAN | Sedoheptulokinase (SHK) (EC 2.7.1.14) (Carbohydrate kinase-like protein) | SHPK | carbohydrate metabolic process [GO:0005975]; cellular response to interleukin-13 [GO:0035963]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; glycerol metabolic process [GO:0006071]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]; phosphorylation [GO:0016310]; regulation of inflammatory response [GO:0050727]; regulation of macrophage activation [GO:0043030] | cytoplasm [GO:0005737]; cytosol [GO:0005829] | ATP binding [GO:0005524]; sedoheptulokinase activity [GO:0050277] | 4933.644186840245 | -0.0383892537191812 | 0.9962172615296 | 1 |
| Q8NBJ9 | Q8NBJ9 | SIDT2_HUMAN | SID1 transmembrane family member 2 | SIDT2 | cell morphogenesis [GO:0000902]; glucose homeostasis [GO:0042593]; regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061178]; response to glucose [GO:0009749]; RNA catabolic process [GO:0006401]; RNA transport [GO:0050658]; type B pancreatic cell development [GO:0003323]; type B pancreatic cell proliferation [GO:0044342] | lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; plasma membrane [GO:0005886] | AP-1 adaptor complex binding [GO:0035650]; AP-2 adaptor complex binding [GO:0035612]; DNA binding [GO:0003677]; double-stranded RNA binding [GO:0003725]; nucleic acid transmembrane transporter activity [GO:0051032]; RNA transmembrane transporter activity [GO:0051033] | 8820.04393370781 | 0.0866803792066816 | 0.914524654556995 | 1 |
| Q9H173 | Q9H173 | SIL1_HUMAN | Nucleotide exchange factor SIL1 (BiP-associated protein) (BAP) | SIL1 | cotranslational protein targeting to membrane [GO:0006613]; intracellular protein transport [GO:0006886]; protein folding [GO:0006457] | endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615] | adenyl-nucleotide exchange factor activity [GO:0000774]; identical protein binding [GO:0042802]; unfolded protein binding [GO:0051082] | 17824.239453649003 | 0.0404998058174989 | 0.991661661768047 | 1 |
| Q96ST3 | Q96ST3 | SIN3A_HUMAN | Paired amphipathic helix protein Sin3a (Histone deacetylase complex subunit Sin3a) (Transcriptional corepressor Sin3a) | SIN3A | activation of innate immune response [GO:0002218]; cellular response to dopamine [GO:1903351]; cellular response to glucose stimulus [GO:0071333]; cellular response to tert-butyl hydroperoxide [GO:0072736]; cerebral cortex neuron differentiation [GO:0021895]; DNA replication [GO:0006260]; hematopoietic progenitor cell differentiation [GO:0002244]; heterochromatin formation [GO:0031507]; in utero embryonic development [GO:0001701]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell migration [GO:0030336]; negative regulation of circadian rhythm [GO:0042754]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of protein localization to nucleus [GO:1900181]; negative regulation of stem cell population maintenance [GO:1902455]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of stem cell population maintenance [GO:1902459]; protein localization [GO:0008104]; regulation of axon extension [GO:0030516]; regulation of hormone levels [GO:0010817]; response to methylglyoxal [GO:0051595]; rhythmic process [GO:0048511]; type I interferon-mediated signaling pathway [GO:0060337] | chromatin [GO:0000785]; histone deacetylase complex [GO:0000118]; kinetochore [GO:0000776]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; Sin3-type complex [GO:0070822]; transcription repressor complex [GO:0017053] | chromatin binding [GO:0003682]; DNA binding [GO:0003677]; RNA binding [GO:0003723]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; transcription corepressor activity [GO:0003714]; transcription regulator inhibitor activity [GO:0140416] | 1974.17300749459 | 0.065072235014319 | 0.999956791051945 | 1 |
| O60292 | O60292 | SI1L3_HUMAN | Signal-induced proliferation-associated 1-like protein 3 (SIPA1-like protein 3) (SPA-1-like protein 3) | SIPA1L3 | cytoskeleton organization [GO:0007010]; epithelial cell morphogenesis [GO:0003382]; establishment of epithelial cell polarity [GO:0090162]; eye development [GO:0001654]; hematopoietic progenitor cell differentiation [GO:0002244]; regulation of small GTPase mediated signal transduction [GO:0051056] | apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; cytoplasm [GO:0005737]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; stress fiber [GO:0001725]; tricellular tight junction [GO:0061689] | GTPase activator activity [GO:0005096] | 6470.61811346812 | -0.100065773609386 | 0.90256764538597 | 1 |
| Q8IXJ6 | Q8IXJ6 | SIR2_HUMAN | NAD-dependent protein deacetylase sirtuin-2 (EC 2.3.1.286) (NAD-dependent protein defatty-acylase sirtuin-2) (EC 2.3.1.-) (Regulatory protein SIR2 homolog 2) (SIR2-like protein 2) | SIRT2 | autophagy [GO:0006914]; cell division [GO:0051301]; cellular lipid catabolic process [GO:0044242]; cellular response to caloric restriction [GO:0061433]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to hypoxia [GO:0071456]; cellular response to oxidative stress [GO:0034599]; epigenetic regulation of gene expression [GO:0040029]; heterochromatin formation [GO:0031507]; innate immune response [GO:0045087]; meiotic cell cycle [GO:0051321]; mitotic nuclear membrane reassembly [GO:0007084]; myelination in peripheral nervous system [GO:0022011]; negative regulation of autophagy [GO:0010507]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of oligodendrocyte progenitor proliferation [GO:0070446]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of striated muscle tissue development [GO:0045843]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NLRP3 inflammasome complex assembly [GO:0044546]; peptidyl-lysine deacetylation [GO:0034983]; positive regulation of attachment of spindle microtubules to kinetochore [GO:0051987]; positive regulation of cell division [GO:0051781]; positive regulation of DNA binding [GO:0043388]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of fatty acid biosynthetic process [GO:0045723]; positive regulation of meiotic nuclear division [GO:0045836]; positive regulation of oocyte maturation [GO:1900195]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of transcription by RNA polymerase II [GO:0045944]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deacetylation [GO:0006476]; rDNA heterochromatin formation [GO:0000183]; regulation of cell cycle [GO:0051726]; regulation of exit from mitosis [GO:0007096]; regulation of myelination [GO:0031641]; regulation of phosphorylation [GO:0042325]; response to redox state [GO:0051775]; substantia nigra development [GO:0021762]; subtelomeric heterochromatin formation [GO:0031509]; tubulin deacetylation [GO:0090042] | centriole [GO:0005814]; centrosome [GO:0005813]; chromatin silencing complex [GO:0005677]; chromosome [GO:0005694]; chromosome, telomeric region [GO:0000781]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; glial cell projection [GO:0097386]; growth cone [GO:0030426]; heterochromatin [GO:0000792]; juxtaparanode region of axon [GO:0044224]; lateral loop [GO:0043219]; meiotic spindle [GO:0072687]; microtubule [GO:0005874]; midbody [GO:0030496]; mitochondrion [GO:0005739]; mitotic spindle [GO:0072686]; myelin sheath [GO:0043209]; nucleolus [GO:0005730]; nucleus [GO:0005634]; paranodal junction [GO:0033010]; paranode region of axon [GO:0033270]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; Schmidt-Lanterman incisure [GO:0043220]; spindle [GO:0005819] | chromatin binding [GO:0003682]; DNA-binding transcription factor binding [GO:0140297]; histone acetyltransferase binding [GO:0035035]; histone deacetylase activity [GO:0004407]; histone deacetylase binding [GO:0042826]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD+ binding [GO:0070403]; NAD-dependent histone deacetylase activity [GO:0017136]; NAD-dependent histone H4K16 deacetylase activity [GO:0046970]; NAD-dependent protein deacetylase activity [GO:0034979]; NAD-dependent protein demyristoylase activity [GO:0140773]; NAD-dependent protein depalmitoylase activity [GO:0140774]; protein lysine deacetylase activity [GO:0033558]; tubulin deacetylase activity [GO:0042903]; ubiquitin binding [GO:0043130]; zinc ion binding [GO:0008270] | 7301.86590789139 | -0.12246104997666 | 0.961552803488433 | 1 |
| Q9P270 | Q9P270 | SLAI2_HUMAN | SLAIN motif-containing protein 2 | SLAIN2 | cytoplasmic microtubule organization [GO:0031122]; microtubule nucleation [GO:0007020]; positive regulation of microtubule polymerization [GO:0031116] | centrosome [GO:0005813]; cytosol [GO:0005829]; microtubule cytoskeleton [GO:0015630]; microtubule plus-end [GO:0035371] | 14881.033891376199 | 0.0803380355872448 | 0.850275801784315 | 1 | |
| P55011 | P55011 | S12A2_HUMAN | Solute carrier family 12 member 2 (Basolateral Na-K-Cl symporter) (Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2) | SLC12A2 | ammonium transmembrane transport [GO:0072488]; cell volume homeostasis [GO:0006884]; cellular response to chemokine [GO:1990869]; cellular response to potassium ion [GO:0035865]; chloride ion homeostasis [GO:0055064]; chloride transmembrane transport [GO:1902476]; gamma-aminobutyric acid signaling pathway [GO:0007214]; hyperosmotic response [GO:0006972]; inorganic anion import across plasma membrane [GO:0098658]; inorganic cation import across plasma membrane [GO:0098659]; intracellular chloride ion homeostasis [GO:0030644]; intracellular potassium ion homeostasis [GO:0030007]; intracellular sodium ion homeostasis [GO:0006883]; maintenance of blood-brain barrier [GO:0035633]; monoatomic ion transport [GO:0006811]; negative regulation of vascular wound healing [GO:0061044]; positive regulation of aspartate secretion [GO:1904450]; positive regulation of cell volume [GO:0045795]; potassium ion homeostasis [GO:0055075]; potassium ion import across plasma membrane [GO:1990573]; regulation of matrix metallopeptidase secretion [GO:1904464]; regulation of spontaneous synaptic transmission [GO:0150003]; sodium ion homeostasis [GO:0055078]; sodium ion import across plasma membrane [GO:0098719]; sodium ion transmembrane transport [GO:0035725]; T cell chemotaxis [GO:0010818]; transepithelial ammonium transport [GO:0070634]; transepithelial chloride transport [GO:0030321]; transport across blood-brain barrier [GO:0150104] | apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell body [GO:0044297]; cell body membrane [GO:0044298]; cell periphery [GO:0071944]; cell projection [GO:0042995]; cell projection membrane [GO:0031253]; cytoplasmic vesicle membrane [GO:0030659]; extracellular exosome [GO:0070062]; extracellular vesicle [GO:1903561]; lateral plasma membrane [GO:0016328]; membrane [GO:0016020]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886] | ammonium transmembrane transporter activity [GO:0008519]; chloride:monoatomic cation symporter activity [GO:0015377]; Hsp90 protein binding [GO:0051879]; metal ion transmembrane transporter activity [GO:0046873]; potassium ion transmembrane transporter activity [GO:0015079]; protein kinase binding [GO:0019901]; protein-folding chaperone binding [GO:0051087]; sodium:potassium:chloride symporter activity [GO:0008511] | 7461.9425101823745 | 0.0156426587182195 | 0.999999994559813 | 1 |
| Q9UHW9 | Q9UHW9 | S12A6_HUMAN | Solute carrier family 12 member 6 (Electroneutral potassium-chloride cotransporter 3) (K-Cl cotransporter 3) | SLC12A6 | ammonium import across plasma membrane [GO:0140157]; angiogenesis [GO:0001525]; cell volume homeostasis [GO:0006884]; cellular hypotonic response [GO:0071476]; cellular hypotonic salinity response [GO:0071477]; cellular response to glucose stimulus [GO:0071333]; chemical synaptic transmission [GO:0007268]; chloride ion homeostasis [GO:0055064]; chloride transmembrane transport [GO:1902476]; monoatomic ion transport [GO:0006811]; potassium ion homeostasis [GO:0055075]; potassium ion import across plasma membrane [GO:1990573]; potassium ion transmembrane transport [GO:0071805] | axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; membrane [GO:0016020]; plasma membrane [GO:0005886]; synapse [GO:0045202] | ammonium transmembrane transporter activity [GO:0008519]; metal ion binding [GO:0046872]; potassium ion transmembrane transporter activity [GO:0015079]; potassium:chloride symporter activity [GO:0015379]; protein kinase binding [GO:0019901] | 4124.284499774595 | 0.234065055547832 | 0.804213838434336 | 1 |
| Q8N697 | Q8N697 | S15A4_HUMAN | Solute carrier family 15 member 4 (Peptide transporter 4) (Peptide/histidine transporter 1) (hPHT1) | SLC15A4 | dipeptide import across plasma membrane [GO:0140206]; histidine transport [GO:0015817]; innate immune response [GO:0045087]; L-histidine transmembrane export from vacuole [GO:0089708]; mast cell homeostasis [GO:0033023]; monoatomic ion transport [GO:0006811]; peptidoglycan transport [GO:0015835]; positive regulation of innate immune response [GO:0045089]; positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway [GO:0070430]; positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070434]; positive regulation of toll-like receptor 7 signaling pathway [GO:0034157]; positive regulation of toll-like receptor 8 signaling pathway [GO:0034161]; positive regulation of toll-like receptor 9 signaling pathway [GO:0034165]; protein transport [GO:0015031]; regulation of isotype switching to IgG isotypes [GO:0048302]; regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [GO:0070424] | early endosome membrane [GO:0031901]; endolysosome membrane [GO:0036020]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579] | dipeptide transmembrane transporter activity [GO:0071916]; L-histidine transmembrane transporter activity [GO:0005290]; peptide:proton symporter activity [GO:0015333]; peptidoglycan transmembrane transporter activity [GO:0015647] | 6477.47111810189 | -0.0845839077684464 | 0.785444332523364 | 1 |
| P53985 | P53985 | MOT1_HUMAN | Monocarboxylate transporter 1 (MCT 1) (Solute carrier family 16 member 1) | SLC16A1 | behavioral response to nutrient [GO:0051780]; carboxylic acid transmembrane transport [GO:1905039]; cellular response to organic cyclic compound [GO:0071407]; centrosome cycle [GO:0007098]; glucose homeostasis [GO:0042593]; lipid metabolic process [GO:0006629]; mevalonate transport [GO:0015728]; monocarboxylic acid transport [GO:0015718]; plasma membrane lactate transport [GO:0035879]; pyruvate catabolic process [GO:0042867]; pyruvate transmembrane transport [GO:1901475]; regulation of insulin secretion [GO:0050796]; response to food [GO:0032094]; succinate transmembrane transport [GO:0071422]; transport across blood-brain barrier [GO:0150104] | apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; centrosome [GO:0005813]; extracellular exosome [GO:0070062]; intracellular membrane-bounded organelle [GO:0043231]; lateral plasma membrane [GO:0016328]; membrane [GO:0016020]; plasma membrane [GO:0005886]; synapse [GO:0045202] | carboxylic acid transmembrane transporter activity [GO:0046943]; identical protein binding [GO:0042802]; lactate transmembrane transporter activity [GO:0015129]; lactate:proton symporter activity [GO:0015650]; mevalonate transmembrane transporter activity [GO:0015130]; monocarboxylic acid transmembrane transporter activity [GO:0008028]; organic cyclic compound binding [GO:0097159]; succinate transmembrane transporter activity [GO:0015141] | 27924.536797806948 | -7.97107455947902E-4 | 0.999999927803385 | 1 |
| Q9NRA2 | Q9NRA2 | S17A5_HUMAN | Sialin (H(+)/nitrate cotransporter) (H(+)/sialic acid cotransporter) (AST) (Membrane glycoprotein HP59) (Solute carrier family 17 member 5) (Vesicular excitatory amino acid transporter) (VEAT) | SLC17A5 | amino acid transport [GO:0006865]; monoatomic anion transport [GO:0006820]; monoatomic ion transport [GO:0006811]; response to bacterium [GO:0009617]; sialic acid transport [GO:0015739] | basolateral plasma membrane [GO:0016323]; cytosol [GO:0005829]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; membrane [GO:0016020]; plasma membrane [GO:0005886]; synaptic vesicle membrane [GO:0030672] | carbohydrate:proton symporter activity [GO:0005351]; D-glucuronate transmembrane transporter activity [GO:0042880]; sialic acid transmembrane transporter activity [GO:0015136]; sialic acid:proton symporter activity [GO:0015538] | 4267.040038854815 | -0.290268573825092 | 0.864368016289468 | 1 |
| Q9UJS0 | Q9UJS0 | S2513_HUMAN | Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial (Calcium-binding mitochondrial carrier protein Aralar2) (ARALAR-related gene 2) (ARALAR2) (Citrin) (Mitochondrial aspartate glutamate carrier 2) (Solute carrier family 25 member 13) | SLC25A13 | aspartate family amino acid metabolic process [GO:0009066]; aspartate transmembrane transport [GO:0015810]; ATP biosynthetic process [GO:0006754]; cellular respiration [GO:0045333]; gluconeogenesis [GO:0006094]; L-glutamate transmembrane transport [GO:0015813]; malate-aspartate shuttle [GO:0043490]; mitochondrial transport [GO:0006839]; response to calcium ion [GO:0051592] | mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886] | 3-sulfino-L-alanine: proton, glutamate antiporter activity [GO:0000514]; acidic amino acid transmembrane transporter activity [GO:0015172]; aspartate:glutamate, proton antiporter activity [GO:0000515]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; L-aspartate transmembrane transporter activity [GO:0015183]; L-glutamate transmembrane transporter activity [GO:0005313] | 7081.16303674424 | -0.083898520612437 | 0.935891042286769 | 1 |
| Q6NUK1 | Q6NUK1 | SCMC1_HUMAN | Mitochondrial adenyl nucleotide antiporter SLC25A24 (Mitochondrial ATP-Mg/Pi carrier protein 1) (Mitochondrial Ca(2+)-dependent solute carrier protein 1) (Short calcium-binding mitochondrial carrier protein 1) (SCaMC-1) (Solute carrier family 25 member 24) | SLC25A24 | adenine nucleotide transport [GO:0051503]; ADP transport [GO:0015866]; ATP transport [GO:0015867]; cellular response to calcium ion [GO:0071277]; cellular response to oxidative stress [GO:0034599]; mitochondrial ATP transmembrane transport [GO:1990544]; mitochondrial transport [GO:0006839] | membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739] | adenine nucleotide transmembrane transporter activity [GO:0000295]; ADP:inorganic phosphate antiporter activity [GO:0140988]; ATP transmembrane transporter activity [GO:0005347]; ATP:inorganic phosphate antiporter activity [GO:0140987]; calcium ion binding [GO:0005509] | 29020.47254937765 | -0.052907013272115 | 0.987305551973652 | 1 |
| Q6P1M0 | Q6P1M0 | S27A4_HUMAN | Long-chain fatty acid transport protein 4 (FATP-4) (Fatty acid transport protein 4) (Arachidonate--CoA ligase) (EC 6.2.1.15) (Long-chain-fatty-acid--CoA ligase) (EC 6.2.1.3) (Solute carrier family 27 member 4) (Very long-chain acyl-CoA synthetase 4) (ACSVL4) (EC 6.2.1.-) | SLC27A4 | activation of GTPase activity [GO:0090630]; establishment of localization in cell [GO:0051649]; fatty acid metabolic process [GO:0006631]; fatty acid transport [GO:0015908]; glucose import in response to insulin stimulus [GO:0044381]; lipid transport across blood-brain barrier [GO:1990379]; long-chain fatty acid import into cell [GO:0044539]; long-chain fatty acid metabolic process [GO:0001676]; long-chain fatty acid transport [GO:0015909]; medium-chain fatty acid transport [GO:0001579]; negative regulation of insulin receptor signaling pathway [GO:0046627]; positive regulation of apoptotic process [GO:0043065]; response to nutrient [GO:0007584]; skin development [GO:0043588]; transport across blood-brain barrier [GO:0150104]; very long-chain fatty acid catabolic process [GO:0042760] | brush border membrane [GO:0031526]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; microvillus [GO:0005902]; plasma membrane [GO:0005886] | arachidonate-CoA ligase activity [GO:0047676]; fatty acid transmembrane transporter activity [GO:0015245]; long-chain fatty acid transporter activity [GO:0005324]; long-chain fatty acid-CoA ligase activity [GO:0004467]; nucleotide binding [GO:0000166]; oleate transmembrane transporter activity [GO:1901480]; oleoyl-CoA ligase activity [GO:0090434]; palmitoyl-CoA ligase activity [GO:0090433]; very long-chain fatty acid-CoA ligase activity [GO:0031957] | 13325.068761210201 | -0.0220537796480724 | 0.999824801634618 | 1 |
| O95528 | O95528 | GTR10_HUMAN | Solute carrier family 2, facilitated glucose transporter member 10 (Glucose transporter type 10) (GLUT-10) | SLC2A10 | artery development [GO:0060840]; cell redox homeostasis [GO:0045454]; circulatory system development [GO:0072359]; dehydroascorbic acid transport [GO:0070837]; embryonic skeletal joint development [GO:0072498]; galactose transmembrane transport [GO:0015757]; glucose import across plasma membrane [GO:0098708]; glucose transmembrane transport [GO:1904659]; hexose transmembrane transport [GO:0008645]; negative regulation of connective tissue growth factor production [GO:0032683]; negative regulation of gene expression [GO:0010629]; negative regulation of integrin-mediated signaling pathway [GO:2001045]; negative regulation of proteoglycan biosynthetic process [GO:1902729]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; positive regulation of gene expression [GO:0010628]; positive regulation of proteoglycan biosynthetic process [GO:1902730]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; regulation of extracellular matrix organization [GO:1903053]; skin development [GO:0043588]; transport across blood-brain barrier [GO:0150104] | cytosol [GO:0005829]; endomembrane system [GO:0012505]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886] | carbohydrate:proton symporter activity [GO:0005351]; D-glucose transmembrane transporter activity [GO:0055056]; dehydroascorbic acid transmembrane transporter activity [GO:0033300]; symporter activity [GO:0015293] | 29315.15167373015 | -1.22925569320471 | 0.997155916059883 | 1 |
| Q96QE2 | Q96QE2 | MYCT_HUMAN | Proton myo-inositol cotransporter (H(+)-myo-inositol cotransporter) (Hmit) (H(+)-myo-inositol symporter) (Solute carrier family 2 member 13) | SLC2A13 | myo-inositol transport [GO:0015798]; positive regulation of amyloid-beta formation [GO:1902004]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104] | apical plasma membrane [GO:0016324]; astrocyte end-foot [GO:0097450]; cell body [GO:0044297]; cell periphery [GO:0071944]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; growth cone [GO:0030426]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; organelle membrane [GO:0031090]; plasma membrane [GO:0005886] | ATPase binding [GO:0051117]; myo-inositol transmembrane transporter activity [GO:0005365]; myo-inositol:proton symporter activity [GO:0005366]; protease binding [GO:0002020] | 7021.936320515165 | 0.050139915874447 | 0.866697169559123 | 1 |
| Q8NEW0 | Q8NEW0 | ZNT7_HUMAN | Zinc transporter 7 (ZnT-7) (Solute carrier family 30 member 7) (Znt-like transporter 2) | SLC30A7 | intracellular zinc ion homeostasis [GO:0006882]; zinc ion import into Golgi lumen [GO:1904257] | cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; Golgi apparatus [GO:0005794]; Golgi cis cisterna membrane [GO:1990674]; Golgi membrane [GO:0000139]; mitochondrion [GO:0005739]; perinuclear region of cytoplasm [GO:0048471]; sarcoplasmic reticulum membrane [GO:0033017]; vesicle [GO:0031982] | zinc ion transmembrane transporter activity [GO:0005385] | 36143.78656556525 | 0.0615421556498194 | 0.908219712966729 | 1 |
| O15431 | O15431 | COPT1_HUMAN | High affinity copper uptake protein 1 (Copper transporter 1) (hCTR1) (Solute carrier family 31 member 1) [Cleaved into: Truncated CTR1 form] | SLC31A1 | angiogenesis [GO:0001525]; copper ion import [GO:0015677]; copper ion transport [GO:0006825]; establishment of localization in cell [GO:0051649]; intracellular copper ion homeostasis [GO:0006878]; plasma membrane copper ion transport [GO:0015679]; protein complex oligomerization [GO:0051259]; silver ion transmembrane transport [GO:1902601]; vascular endothelial growth factor receptor-2 signaling pathway [GO:0036324]; xenobiotic transport [GO:0042908] | apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; early endosome membrane [GO:0031901]; intercalated disc [GO:0014704]; late endosome membrane [GO:0031902]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038] | copper ion binding [GO:0005507]; copper ion transmembrane transporter activity [GO:0005375]; identical protein binding [GO:0042802]; silver ion transmembrane transporter activity [GO:0015080]; xenobiotic transmembrane transporter activity [GO:0042910] | 21973.1487575725 | 0.0167725589079562 | 0.995089084472509 | 1 |
| Q9HBR0 | Q9HBR0 | S38AA_HUMAN | Solute carrier family 38 member 10 (Amino acid transporter SLC38A10) | SLC38A10 | amino acid transmembrane transport [GO:0003333]; bone development [GO:0060348] | Golgi apparatus [GO:0005794]; membrane [GO:0016020] | L-amino acid transmembrane transporter activity [GO:0015179] | 9710.464280728029 | -0.165851884001319 | 0.726202814399943 | 1 |
| Q92504 | Q92504 | S39A7_HUMAN | Zinc transporter SLC39A7 (Histidine-rich membrane protein Ke4) (Really interesting new gene 5 protein) (Solute carrier family 39 member 7) (Zrt-, Irt-like protein 7) (ZIP7) | SLC39A7 | B cell differentiation [GO:0030183]; intracellular zinc ion homeostasis [GO:0006882]; regulation of ferroptosis [GO:0110075]; skin epidermis development [GO:0098773]; zinc ion transmembrane transport [GO:0071577] | endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; nucleoplasm [GO:0005654] | zinc ion transmembrane transporter activity [GO:0005385] | 16505.07549683255 | 0.27778540426045 | 0.799908450605423 | 1 |
| P08195 | P08195 | 4F2_HUMAN | Amino acid transporter heavy chain SLC3A2 (4F2 cell-surface antigen heavy chain) (4F2hc) (4F2 heavy chain antigen) (Lymphocyte activation antigen 4F2 large subunit) (Solute carrier family 3 member 2) (CD antigen CD98) | SLC3A2 | amino acid transport [GO:0006865]; calcium ion transport [GO:0006816]; carbohydrate metabolic process [GO:0005975]; isoleucine transport [GO:0015818]; L-alanine import across plasma membrane [GO:1904273]; L-histidine transport [GO:1902024]; L-leucine import across plasma membrane [GO:1903801]; leucine import across plasma membrane [GO:0098713]; leucine transport [GO:0015820]; methionine transport [GO:0015821]; phenylalanine transport [GO:0015823]; proline transport [GO:0015824]; response to exogenous dsRNA [GO:0043330]; symbiont entry into host cell [GO:0046718]; thyroid hormone transport [GO:0070327]; tryptophan transport [GO:0015827]; tyrosine transport [GO:0015828]; valine transport [GO:0015829] | amino acid transport complex [GO:1990184]; anchoring junction [GO:0070161]; apical plasma membrane [GO:0016324]; apical pole of neuron [GO:0044225]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; lysosomal membrane [GO:0005765]; melanosome [GO:0042470]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; synapse [GO:0045202] | aromatic amino acid transmembrane transporter activity [GO:0015173]; cadherin binding [GO:0045296]; calcium:sodium antiporter activity [GO:0005432]; double-stranded RNA binding [GO:0003725]; exogenous protein binding [GO:0140272]; L-alanine transmembrane transporter activity [GO:0015180]; L-leucine transmembrane transporter activity [GO:0015190]; neutral L-amino acid secondary active transmembrane transporter activity [GO:0005294]; neutral L-amino acid transmembrane transporter activity [GO:0015175]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; virus receptor activity [GO:0001618] | 164389.253509362 | -0.0273444243456567 | 0.997136969230749 | 1 |
| Q9Y6R1 | Q9Y6R1 | S4A4_HUMAN | Electrogenic sodium bicarbonate cotransporter 1 (Sodium bicarbonate cotransporter) (Na(+)/HCO3(-) cotransporter) (Solute carrier family 4 member 4) (kNBC1) | SLC4A4 | bicarbonate transport [GO:0015701]; positive regulation of glycolytic process [GO:0045821]; regulation of intracellular pH [GO:0051453]; regulation of membrane potential [GO:0042391]; sodium ion export across plasma membrane [GO:0036376]; sodium ion transmembrane transport [GO:0035725]; sodium ion transport [GO:0006814]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104] | basolateral plasma membrane [GO:0016323]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; plasma membrane [GO:0005886] | identical protein binding [GO:0042802]; monoatomic anion transmembrane transporter activity [GO:0008509]; sodium:bicarbonate symporter activity [GO:0008510]; solute:inorganic anion antiporter activity [GO:0005452]; symporter activity [GO:0015293] | 6244.2153450764745 | 0.559185896617142 | 0.732177006009973 | 1 |
| P30825 | P30825 | CTR1_HUMAN | High affinity cationic amino acid transporter 1 (CAT-1) (CAT1) (Ecotropic retroviral leukemia receptor homolog) (Ecotropic retrovirus receptor homolog) (Solute carrier family 7 member 1) (System Y+ basic amino acid transporter) | SLC7A1 | amino acid import across plasma membrane [GO:0089718]; amino acid transport [GO:0006865]; L-amino acid transport [GO:0015807]; L-arginine import across plasma membrane [GO:0097638]; L-arginine transmembrane transport [GO:1903826]; L-histidine import across plasma membrane [GO:1903810]; L-ornithine transmembrane transport [GO:1903352]; lysine transport [GO:0015819]; ornithine transport [GO:0015822]; positive regulation of T cell proliferation [GO:0042102]; transport across blood-brain barrier [GO:0150104] | apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; membrane [GO:0016020]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991] | amino acid transmembrane transporter activity [GO:0015171]; basic amino acid transmembrane transporter activity [GO:0015174]; L-arginine transmembrane transporter activity [GO:0061459]; L-histidine transmembrane transporter activity [GO:0005290]; L-lysine transmembrane transporter activity [GO:0015189]; L-ornithine transmembrane transporter activity [GO:0000064]; virus receptor activity [GO:0001618] | 17814.758525310397 | 0.0981573496898119 | 0.990708084460005 | 1 |
| P32418 | P32418 | NAC1_HUMAN | Sodium/calcium exchanger 1 (Na(+)/Ca(2+)-exchange protein 1) (Solute carrier family 8 member 1) | SLC8A1 | calcium ion export [GO:1901660]; calcium ion homeostasis [GO:0055074]; calcium ion import [GO:0070509]; calcium ion import across plasma membrane [GO:0098703]; calcium ion transmembrane import into cytosol [GO:0097553]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport into cytosol [GO:0060402]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cell communication by electrical coupling involved in cardiac conduction [GO:0086064]; cellular response to caffeine [GO:0071313]; cellular response to reactive oxygen species [GO:0034614]; intracellular calcium ion homeostasis [GO:0006874]; intracellular sodium ion homeostasis [GO:0006883]; membrane depolarization during cardiac muscle cell action potential [GO:0086012]; monoatomic ion transport [GO:0006811]; muscle contraction [GO:0006936]; negative regulation of cytosolic calcium ion concentration [GO:0051481]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; positive regulation of bone mineralization [GO:0030501]; positive regulation of the force of heart contraction [GO:0098735]; regulation of cardiac conduction [GO:1903779]; regulation of cardiac muscle contraction by calcium ion signaling [GO:0010882]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling [GO:0010649]; regulation of gene expression [GO:0010468]; regulation of heart rate [GO:0002027]; regulation of the force of heart contraction [GO:0002026]; relaxation of cardiac muscle [GO:0055119]; relaxation of smooth muscle [GO:0044557]; response to muscle stretch [GO:0035994]; sodium ion export across plasma membrane [GO:0036376]; sodium ion import across plasma membrane [GO:0098719]; sodium ion transmembrane transport [GO:0035725]; vascular associated smooth muscle contraction [GO:0014829] | axon [GO:0030424]; axon terminus [GO:0043679]; cell periphery [GO:0071944]; dendrite [GO:0030425]; intercalated disc [GO:0014704]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]; sarcolemma [GO:0042383]; synapse [GO:0045202]; T-tubule [GO:0030315]; Z disc [GO:0030018] | ankyrin binding [GO:0030506]; calcium ion binding [GO:0005509]; calcium:sodium antiporter activity [GO:0005432]; calmodulin binding [GO:0005516]; cytoskeletal protein binding [GO:0008092]; transmembrane transporter binding [GO:0044325] | 4222.56797348451 | -0.130607680287571 | 0.864563266179549 | 1 |
| P19634 | P19634 | SL9A1_HUMAN | Sodium/hydrogen exchanger 1 (APNH) (Na(+)/H(+) antiporter, amiloride-sensitive) (Na(+)/H(+) exchanger 1) (NHE-1) (Solute carrier family 9 member 1) | SLC9A1 | cardiac muscle cell contraction [GO:0086003]; cardiac muscle cell differentiation [GO:0055007]; cell migration [GO:0016477]; cellular response to acidic pH [GO:0071468]; cellular response to antibiotic [GO:0071236]; cellular response to cold [GO:0070417]; cellular response to electrical stimulus [GO:0071257]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to mechanical stimulus [GO:0071260]; cellular response to organic cyclic compound [GO:0071407]; intracellular sodium ion homeostasis [GO:0006883]; maintenance of cell polarity [GO:0030011]; monoatomic ion transport [GO:0006811]; negative regulation of apoptotic process [GO:0043066]; positive regulation of action potential [GO:0045760]; positive regulation of apoptotic process [GO:0043065]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of calcium:sodium antiporter activity [GO:1903281]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of cell growth [GO:0030307]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of the force of heart contraction [GO:0098735]; positive regulation of transcription by RNA polymerase II [GO:0045944]; potassium ion transmembrane transport [GO:0071805]; protein complex oligomerization [GO:0051259]; proton transmembrane transport [GO:1902600]; regulation of cardiac muscle cell membrane potential [GO:0086036]; regulation of cardiac muscle contraction by calcium ion signaling [GO:0010882]; regulation of focal adhesion assembly [GO:0051893]; regulation of intracellular pH [GO:0051453]; regulation of pH [GO:0006885]; regulation of stress fiber assembly [GO:0051492]; regulation of the force of heart contraction by cardiac conduction [GO:0086092]; response to acidic pH [GO:0010447]; response to muscle stretch [GO:0035994]; sodium ion export across plasma membrane [GO:0036376]; sodium ion import across plasma membrane [GO:0098719]; stem cell differentiation [GO:0048863] | apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; cation-transporting ATPase complex [GO:0090533]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; intercalated disc [GO:0014704]; lamellipodium [GO:0030027]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; T-tubule [GO:0030315] | calcium-dependent protein binding [GO:0048306]; calmodulin binding [GO:0005516]; identical protein binding [GO:0042802]; ion binding [GO:0043167]; molecular adaptor activity [GO:0060090]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phospholipid binding [GO:0005543]; potassium:proton antiporter activity [GO:0015386]; protein phosphatase 2B binding [GO:0030346]; protein-macromolecule adaptor activity [GO:0030674]; sodium:proton antiporter activity [GO:0015385]; sodium:proton antiporter activity involved in regulation of cardiac muscle cell membrane potential [GO:0086040] | 7107.64825819388 | 0.0834327754398147 | 0.811883929124333 | 1 |
| Q92581 | Q92581 | SL9A6_HUMAN | Sodium/hydrogen exchanger 6 (Na(+)/H(+) exchanger 6) (NHE-6) (Solute carrier family 9 member 6) | SLC9A6 | axon extension [GO:0048675]; dendrite extension [GO:0097484]; establishment of cell polarity [GO:0030010]; monoatomic ion transport [GO:0006811]; neuron projection morphogenesis [GO:0048812]; potassium ion transmembrane transport [GO:0071805]; regulation of intracellular pH [GO:0051453]; sodium ion import across plasma membrane [GO:0098719] | early endosome membrane [GO:0031901]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; late endosome membrane [GO:0031902]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; recycling endosome membrane [GO:0055038] | identical protein binding [GO:0042802]; potassium:proton antiporter activity [GO:0015386]; sodium:proton antiporter activity [GO:0015385] | 23472.7454446541 | 0.0502266308038612 | 0.719785104913319 | 1 |
| Q96T83 | Q96T83 | SL9A7_HUMAN | Sodium/hydrogen exchanger 7 (Na(+)/H(+) exchanger 7) (NHE-7) (Solute carrier family 9 member 7) | SLC9A7 | monoatomic ion transport [GO:0006811]; potassium ion transmembrane transport [GO:0071805]; regulation of Golgi lumen acidification [GO:1905526]; regulation of intracellular pH [GO:0051453]; regulation of pH [GO:0006885]; sodium ion import across plasma membrane [GO:0098719] | Golgi membrane [GO:0000139]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; recycling endosome membrane [GO:0055038]; trans-Golgi network [GO:0005802] | potassium:proton antiporter activity [GO:0015386]; sodium:proton antiporter activity [GO:0015385] | 55911.9817930836 | -0.0891525196727284 | 0.752551619584735 | 1 |
| Q9H2G2 | Q9H2G2 | SLK_HUMAN | STE20-like serine/threonine-protein kinase (STE20-like kinase) (hSLK) (EC 2.7.11.1) (CTCL tumor antigen se20-9) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (Serine/threonine-protein kinase 2) | SLK | apoptotic process [GO:0006915]; cytoplasmic microtubule organization [GO:0031122]; protein autophosphorylation [GO:0046777]; regulation of apoptotic process [GO:0042981]; regulation of cell migration [GO:0030334]; regulation of focal adhesion assembly [GO:0051893] | cell leading edge [GO:0031252]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; perinuclear region of cytoplasm [GO:0048471] | ATP binding [GO:0005524]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] | 16040.630062946 | 0.057038529128755 | 0.999999973575899 | 1 |
| Q9NWH9 | Q9NWH9 | SLTM_HUMAN | SAFB-like transcription modulator (Modulator of estrogen-induced transcription) | SLTM | apoptotic process [GO:0006915]; regulation of mRNA processing [GO:0050684]; regulation of transcription by RNA polymerase II [GO:0006357] | nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] | RNA binding [GO:0003723]; sequence-specific DNA binding [GO:0043565] | 7858.284280386205 | 0.187545356536767 | 0.84092926221456 | 1 |
| Q13485 | Q13485 | SMAD4_HUMAN | Mothers against decapentaplegic homolog 4 (MAD homolog 4) (Mothers against DPP homolog 4) (Deletion target in pancreatic carcinoma 4) (SMAD family member 4) (SMAD 4) (Smad4) (hSMAD4) | SMAD4 | activin receptor signaling pathway [GO:0032924]; adrenal gland development [GO:0030325]; anatomical structure morphogenesis [GO:0009653]; atrioventricular canal development [GO:0036302]; atrioventricular valve formation [GO:0003190]; axon guidance [GO:0007411]; BMP signaling pathway [GO:0030509]; brainstem development [GO:0003360]; branching involved in ureteric bud morphogenesis [GO:0001658]; cardiac conduction system development [GO:0003161]; cardiac muscle hypertrophy in response to stress [GO:0014898]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to BMP stimulus [GO:0071773]; cellular response to glucose stimulus [GO:0071333]; cellular response to transforming growth factor beta stimulus [GO:0071560]; developmental growth [GO:0048589]; DNA-templated transcription [GO:0006351]; embryonic digit morphogenesis [GO:0042733]; endocardial cell differentiation [GO:0060956]; endothelial cell activation [GO:0042118]; epithelial cell migration [GO:0010631]; epithelial to mesenchymal transition [GO:0001837]; epithelial to mesenchymal transition involved in endocardial cushion formation [GO:0003198]; ERK1 and ERK2 cascade [GO:0070371]; extrinsic apoptotic signaling pathway [GO:0097191]; female gonad morphogenesis [GO:0061040]; formation of anatomical boundary [GO:0048859]; gastrulation with mouth forming second [GO:0001702]; in utero embryonic development [GO:0001701]; interleukin-6-mediated signaling pathway [GO:0070102]; intracellular iron ion homeostasis [GO:0006879]; intracellular signal transduction [GO:0035556]; left ventricular cardiac muscle tissue morphogenesis [GO:0003220]; mesendoderm development [GO:0048382]; metanephric mesenchyme morphogenesis [GO:0072133]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cardiac muscle hypertrophy [GO:0010614]; negative regulation of cardiac myofibril assembly [GO:1905305]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nephrogenic mesenchyme morphogenesis [GO:0072134]; neural crest cell differentiation [GO:0014033]; neuron fate specification [GO:0048665]; osteoblast differentiation [GO:0001649]; outflow tract septum morphogenesis [GO:0003148]; ovarian follicle development [GO:0001541]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell proliferation involved in heart valve morphogenesis [GO:0003251]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of extracellular matrix assembly [GO:1901203]; positive regulation of follicle-stimulating hormone secretion [GO:0046881]; positive regulation of gene expression [GO:0010628]; positive regulation of luteinizing hormone secretion [GO:0033686]; positive regulation of miRNA transcription [GO:1902895]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; regulation of DNA-templated transcription [GO:0006355]; regulation of hair follicle development [GO:0051797]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015]; regulation of transforming growth factor beta2 production [GO:0032909]; response to hypoxia [GO:0001666]; response to transforming growth factor beta [GO:0071559]; sebaceous gland development [GO:0048733]; secondary palate development [GO:0062009]; seminiferous tubule development [GO:0072520]; single fertilization [GO:0007338]; SMAD protein signal transduction [GO:0060395]; somite rostral/caudal axis specification [GO:0032525]; spermatogenesis [GO:0007283]; transcription by RNA polymerase II [GO:0006366]; transforming growth factor beta receptor signaling pathway [GO:0007179]; uterus development [GO:0060065]; ventricular septum morphogenesis [GO:0060412] | activin responsive factor complex [GO:0032444]; centrosome [GO:0005813]; chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; heteromeric SMAD protein complex [GO:0071144]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; SMAD protein complex [GO:0071141]; transcription regulator complex [GO:0005667] | chromatin binding [GO:0003682]; collagen binding [GO:0005518]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; filamin binding [GO:0031005]; I-SMAD binding [GO:0070411]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; R-SMAD binding [GO:0070412]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; sequence-specific DNA binding [GO:0043565]; sulfate binding [GO:0043199]; transcription cis-regulatory region binding [GO:0000976]; transcription coactivator binding [GO:0001223]; transcription corepressor binding [GO:0001222] | 4699.016069909911 | -0.13016559801137 | 0.837027663218375 | 1 |
| P28370 | P28370 | SMCA1_HUMAN | Probable global transcription activator SNF2L1 (EC 3.6.4.-) (ATP-dependent helicase SMARCA1) (Nucleosome-remodeling factor subunit SNF2L) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1) | SMARCA1 | brain development [GO:0007420]; chromatin remodeling [GO:0006338]; neuron differentiation [GO:0030182]; nucleosome organization [GO:0034728]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of DNA-templated transcription [GO:0006355] | ATPase complex [GO:1904949]; CERF complex [GO:0090537]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; NURF complex [GO:0016589] | ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-dependent chromatin remodeler activity [GO:0140658]; ATP-dependent DNA/DNA annealing activity [GO:0036310]; DNA binding [GO:0003677]; helicase activity [GO:0004386]; histone binding [GO:0042393]; nucleosome binding [GO:0031491]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629] | 15262.73307892915 | 0.131816307873313 | 0.682730525033558 | 1 |
| P51531 | P51531 | SMCA2_HUMAN | Probable global transcription activator SNF2L2 (EC 3.6.4.-) (ATP-dependent helicase SMARCA2) (BRG1-associated factor 190B) (BAF190B) (Protein brahma homolog) (hBRM) (SNF2-alpha) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2) | SMARCA2 | chromatin remodeling [GO:0006338]; negative regulation of cell differentiation [GO:0045596]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; positive regulation of cell differentiation [GO:0045597]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of double-strand break repair [GO:2000781]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of stem cell population maintenance [GO:1902459]; positive regulation of T cell differentiation [GO:0045582]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of DNA-templated transcription [GO:0006355]; regulation of G0 to G1 transition [GO:0070316]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of mitotic metaphase/anaphase transition [GO:0030071]; regulation of nucleotide-excision repair [GO:2000819]; regulation of transcription by RNA polymerase II [GO:0006357]; spermatid development [GO:0007286] | bBAF complex [GO:0140092]; brahma complex [GO:0035060]; chromatin [GO:0000785]; GBAF complex [GO:0140288]; intermediate filament cytoskeleton [GO:0045111]; intracellular membrane-bounded organelle [GO:0043231]; nBAF complex [GO:0071565]; npBAF complex [GO:0071564]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; SWI/SNF complex [GO:0016514] | ATP binding [GO:0005524]; ATP-dependent activity, acting on DNA [GO:0008094]; ATP-dependent chromatin remodeler activity [GO:0140658]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; helicase activity [GO:0004386]; histone binding [GO:0042393]; hydrolase activity [GO:0016787]; transcription cis-regulatory region binding [GO:0000976]; transcription coactivator activity [GO:0003713] | 5385.47757640447 | 0.074914307434293 | 0.983252000707193 | 1 |
| P51532 | P51532 | SMCA4_HUMAN | Transcription activator BRG1 (EC 3.6.4.-) (ATP-dependent helicase SMARCA4) (BRG1-associated factor 190A) (BAF190A) (Mitotic growth and transcription activator) (Protein BRG-1) (Protein brahma homolog 1) (SNF2-beta) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4) | SMARCA4 | chromatin remodeling [GO:0006338]; negative regulation of androgen receptor signaling pathway [GO:0060766]; negative regulation of cell differentiation [GO:0045596]; negative regulation of cell growth [GO:0030308]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; neural retina development [GO:0003407]; nucleosome disassembly [GO:0006337]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of cell differentiation [GO:0045597]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of double-strand break repair [GO:2000781]; positive regulation of glucose mediated signaling pathway [GO:1902661]; positive regulation of miRNA transcription [GO:1902895]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of stem cell population maintenance [GO:1902459]; positive regulation of T cell differentiation [GO:0045582]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of nucleolar large rRNA by RNA polymerase I [GO:1901838]; positive regulation of Wnt signaling pathway [GO:0030177]; regulation of G0 to G1 transition [GO:0070316]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of mitotic metaphase/anaphase transition [GO:0030071]; regulation of nucleotide-excision repair [GO:2000819]; regulation of transcription by RNA polymerase II [GO:0006357]; RNA polymerase I preinitiation complex assembly [GO:0001188]; transcription initiation-coupled chromatin remodeling [GO:0045815] | bBAF complex [GO:0140092]; chromatin [GO:0000785]; extracellular space [GO:0005615]; fibrillar center [GO:0001650]; GBAF complex [GO:0140288]; kinetochore [GO:0000776]; membrane [GO:0016020]; nBAF complex [GO:0071565]; npBAF complex [GO:0071564]; nuclear matrix [GO:0016363]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; RSC-type complex [GO:0016586]; SWI/SNF complex [GO:0016514] | ATP binding [GO:0005524]; ATP-dependent activity, acting on DNA [GO:0008094]; ATP-dependent chromatin remodeler activity [GO:0140658]; DNA binding [GO:0003677]; DNA polymerase binding [GO:0070182]; helicase activity [GO:0004386]; hydrolase activity [GO:0016787]; lysine-acetylated histone binding [GO:0070577]; nuclear androgen receptor binding [GO:0050681]; p53 binding [GO:0002039]; RNA binding [GO:0003723]; Tat protein binding [GO:0030957]; transcription coactivator activity [GO:0003713]; transcription coregulator binding [GO:0001221]; transcription corepressor activity [GO:0003714] | 3159.9146570785597 | -0.0742471642971047 | 0.894965929378936 | 1 |
| Q92922 | Q92922 | SMRC1_HUMAN | SWI/SNF complex subunit SMARCC1 (BRG1-associated factor 155) (BAF155) (SWI/SNF complex 155 kDa subunit) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1) | SMARCC1 | animal organ morphogenesis [GO:0009887]; chromatin remodeling [GO:0006338]; insulin receptor signaling pathway [GO:0008286]; negative regulation of cell differentiation [GO:0045596]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; nervous system development [GO:0007399]; nucleosome disassembly [GO:0006337]; positive regulation of cell differentiation [GO:0045597]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of double-strand break repair [GO:2000781]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of stem cell population maintenance [GO:1902459]; positive regulation of T cell differentiation [GO:0045582]; positive regulation of transcription by RNA polymerase II [GO:0045944]; prostate gland development [GO:0030850]; regulation of G0 to G1 transition [GO:0070316]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of mitotic metaphase/anaphase transition [GO:0030071]; regulation of nucleotide-excision repair [GO:2000819]; regulation of transcription by RNA polymerase II [GO:0006357] | brahma complex [GO:0035060]; chromatin [GO:0000785]; cytoplasm [GO:0005737]; GBAF complex [GO:0140288]; kinetochore [GO:0000776]; male germ cell nucleus [GO:0001673]; nBAF complex [GO:0071565]; npBAF complex [GO:0071564]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; RSC-type complex [GO:0016586]; SWI/SNF complex [GO:0016514]; XY body [GO:0001741] | histone binding [GO:0042393]; nucleosomal DNA binding [GO:0031492]; transcription coactivator activity [GO:0003713] | 5251.008676276185 | -0.113880125883138 | 0.978415897222061 | 1 |
| Q8TAQ2 | Q8TAQ2 | SMRC2_HUMAN | SWI/SNF complex subunit SMARCC2 (BRG1-associated factor 170) (BAF170) (SWI/SNF complex 170 kDa subunit) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2) | SMARCC2 | chromatin remodeling [GO:0006338]; negative regulation of DNA-templated transcription [GO:0045892]; nervous system development [GO:0007399]; nucleosome disassembly [GO:0006337]; positive regulation of cell differentiation [GO:0045597]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of double-strand break repair [GO:2000781]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of T cell differentiation [GO:0045582]; regulation of G0 to G1 transition [GO:0070316]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of mitotic metaphase/anaphase transition [GO:0030071]; regulation of nucleotide-excision repair [GO:2000819]; regulation of transcription by RNA polymerase II [GO:0006357] | bBAF complex [GO:0140092]; brahma complex [GO:0035060]; chromatin [GO:0000785]; kinetochore [GO:0000776]; nBAF complex [GO:0071565]; npBAF complex [GO:0071564]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; RSC-type complex [GO:0016586]; SWI/SNF complex [GO:0016514] | histone binding [GO:0042393]; nucleosomal DNA binding [GO:0031492]; transcription coactivator activity [GO:0003713] | 6705.631306014135 | -0.0764891154030298 | 0.999970151062045 | 1 |
| Q6STE5 | Q6STE5 | SMRD3_HUMAN | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 (60 kDa BRG-1/Brm-associated factor subunit C) (BRG1-associated factor 60C) (BAF60C) | SMARCD3 | cardiac right ventricle formation [GO:0003219]; chromatin remodeling [GO:0006338]; muscle cell differentiation [GO:0042692]; nervous system development [GO:0007399]; neural retina development [GO:0003407]; nucleosome disassembly [GO:0006337]; positive regulation of cell differentiation [GO:0045597]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of double-strand break repair [GO:2000781]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of smooth muscle cell differentiation [GO:0051152]; positive regulation of T cell differentiation [GO:0045582]; regulation of G0 to G1 transition [GO:0070316]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of mitotic metaphase/anaphase transition [GO:0030071]; regulation of nucleotide-excision repair [GO:2000819]; regulation of transcription by RNA polymerase II [GO:0006357]; secondary heart field specification [GO:0003139] | brahma complex [GO:0035060]; chromatin [GO:0000785]; cytoplasm [GO:0005737]; nBAF complex [GO:0071565]; npBAF complex [GO:0071564]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; SWI/SNF complex [GO:0016514] | chromatin binding [GO:0003682]; DNA-binding transcription factor binding [GO:0140297]; nuclear receptor binding [GO:0016922]; nuclear receptor coactivator activity [GO:0030374]; signaling receptor binding [GO:0005102]; transcription coactivator activity [GO:0003713]; transcription coregulator activity [GO:0003712]; transcription coregulator binding [GO:0001221] | 7313.833611950175 | -0.191782194915028 | 0.749901325046047 | 1 |
| O95347 | O95347 | SMC2_HUMAN | Structural maintenance of chromosomes protein 2 (SMC protein 2) (SMC-2) (Chromosome-associated protein E) (hCAP-E) (XCAP-E homolog) | SMC2 | cell division [GO:0051301]; kinetochore organization [GO:0051383]; meiotic chromosome condensation [GO:0010032]; meiotic chromosome segregation [GO:0045132]; mitotic chromosome condensation [GO:0007076]; positive regulation of chromosome condensation [GO:1905821]; positive regulation of chromosome segregation [GO:0051984]; positive regulation of chromosome separation [GO:1905820] | chromatin [GO:0000785]; condensed chromosome [GO:0000793]; condensed nuclear chromosome [GO:0000794]; condensin complex [GO:0000796]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nuclear chromosome [GO:0000228]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] | ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; chromatin binding [GO:0003682]; single-stranded DNA binding [GO:0003697] | 6311.4425747733 | -0.0190795889020563 | 0.999721257008929 | 1 |
| Q8ND04 | Q8ND04 | SMG8_HUMAN | Nonsense-mediated mRNA decay factor SMG8 (Amplified in breast cancer gene 2 protein) (Protein smg-8 homolog) | SMG8 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; regulation of protein kinase activity [GO:0045859] | cytosol [GO:0005829] | 7894.743125076765 | 0.00279205574974783 | 0.999999962507376 | 1 | |
| Q9H0W8 | Q9H0W8 | SMG9_HUMAN | Nonsense-mediated mRNA decay factor SMG9 | SMG9 | brain development [GO:0007420]; eye development [GO:0001654]; heart development [GO:0007507]; in utero embryonic development [GO:0001701]; negative regulation of apoptotic process [GO:0043066]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184] | cytosol [GO:0005829] | identical protein binding [GO:0042802] | 6825.6959041142745 | 0.111417816156794 | 0.660528703131353 | 1 |
| P17405 | P17405 | ASM_HUMAN | Sphingomyelin phosphodiesterase (EC 3.1.4.12) (EC 3.1.4.3) (Acid sphingomyelinase) (aSMase) [Cleaved into: Sphingomyelin phosphodiesterase, processed form] | SMPD1 | cellular response to calcium ion [GO:0071277]; cellular response to UV [GO:0034644]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glycosphingolipid catabolic process [GO:0046479]; negative regulation of MAP kinase activity [GO:0043407]; nervous system development [GO:0007399]; plasma membrane repair [GO:0001778]; positive regulation of apoptotic process [GO:0043065]; positive regulation of endocytosis [GO:0045807]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of viral entry into host cell [GO:0046598]; response to cocaine [GO:0042220]; response to interleukin-1 [GO:0070555]; response to ionizing radiation [GO:0010212]; response to tumor necrosis factor [GO:0034612]; response to type I interferon [GO:0034340]; response to virus [GO:0009615]; response to xenobiotic stimulus [GO:0009410]; signal transduction [GO:0007165]; sphingomyelin catabolic process [GO:0006685]; sphingomyelin metabolic process [GO:0006684]; symbiont entry into host cell [GO:0046718]; termination of signal transduction [GO:0023021]; wound healing [GO:0042060] | endolysosome [GO:0036019]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; lamellar body [GO:0042599]; lipid droplet [GO:0005811]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; plasma membrane [GO:0005886] | acid sphingomyelin phosphodiesterase activity [GO:0061750]; hydrolase activity, acting on glycosyl bonds [GO:0016798]; phosphatidylcholine phospholipase C activity [GO:0034480]; sphingomyelin phosphodiesterase activity [GO:0004767]; zinc ion binding [GO:0008270] | 49164.70549243 | 0.0638624318487915 | 0.738362460374808 | 1 |
| Q9HAU4 | Q9HAU4 | SMUF2_HUMAN | E3 ubiquitin-protein ligase SMURF2 (hSMURF2) (EC 2.3.2.26) (HECT-type E3 ubiquitin transferase SMURF2) (SMAD ubiquitination regulatory factor 2) (SMAD-specific E3 ubiquitin-protein ligase 2) | SMURF2 | negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of trophoblast cell migration [GO:1901165]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015]; ubiquitin-dependent protein catabolic process [GO:0006511]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane raft [GO:0045121]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ubiquitin ligase complex [GO:0000151] | identical protein binding [GO:0042802]; SMAD binding [GO:0046332]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842] | 8970.079976476885 | 0.0964075404865386 | 0.998713198652056 | 1 |
| Q9H7B4 | Q9H7B4 | SMYD3_HUMAN | Histone-lysine N-methyltransferase SMYD3 (EC 2.1.1.354) (SET and MYND domain-containing protein 3) (Zinc finger MYND domain-containing protein 1) | SMYD3 | cellular response to dexamethasone stimulus [GO:0071549]; establishment of protein localization [GO:0045184]; methylation [GO:0032259]; myotube cell development [GO:0014904]; nucleosome assembly [GO:0006334]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of transcription by RNA polymerase II [GO:0045944] | cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] | histone H3K36 dimethyltransferase activity [GO:0140954]; histone H3K4 trimethyltransferase activity [GO:0140999]; histone H4 methyltransferase activity [GO:0140939]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II complex binding [GO:0000993]; RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding [GO:0001162] | 6640.54493731946 | -0.0853626281978658 | 0.841431944534817 | 1 |
| Q6GMV2 | Q6GMV2 | SMYD5_HUMAN | Histone-lysine N-trimethyltransferase SMYD5 (EC 2.1.1.372) (Protein NN8-4AG) (Retinoic acid-induced protein 15) (SET and MYND domain-containing protein 5) ([histone H4]-lysine20 N-trimethyltransferase SMYD5) | SMYD5 | methylation [GO:0032259]; negative regulation of gene expression, epigenetic [GO:0045814]; regulation of stem cell differentiation [GO:2000736]; regulation of stem cell division [GO:2000035]; retrotransposon silencing by heterochromatin formation [GO:0141005] | histone H4K20 methyltransferase activity [GO:0042799]; histone H4K20 trimethyltransferase activity [GO:0140943]; metal ion binding [GO:0046872] | 11138.034824964448 | -0.04343100942398 | 0.939035915680236 | 1 | |
| Q7KZF4 | Q7KZF4 | SND1_HUMAN | Staphylococcal nuclease domain-containing protein 1 (EC 3.1.31.1) (100 kDa coactivator) (EBNA2 coactivator p100) (Tudor domain-containing protein 11) (p100 co-activator) | SND1 | miRNA catabolic process [GO:0010587]; mRNA catabolic process [GO:0006402]; osteoblast differentiation [GO:0001649]; regulation of cell cycle process [GO:0010564]; regulatory ncRNA-mediated gene silencing [GO:0031047] | cytosol [GO:0005829]; dense body [GO:0097433]; extracellular exosome [GO:0070062]; melanosome [GO:0042470]; membrane [GO:0016020]; nucleus [GO:0005634]; RISC complex [GO:0016442] | cadherin binding [GO:0045296]; endonuclease activity [GO:0004519]; endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters [GO:0016894]; nuclease activity [GO:0004518]; RISC complex binding [GO:1905172]; RNA binding [GO:0003723]; RNA endonuclease activity [GO:0004521]; transcription coregulator activity [GO:0003712] | 113454.63568291749 | -0.0584534727754814 | 0.999994427697535 | 1 |
| Q96DI7 | Q96DI7 | SNR40_HUMAN | U5 small nuclear ribonucleoprotein 40 kDa protein (U5 snRNP 40 kDa protein) (U5-40K) (38 kDa-splicing factor) (Prp8-binding protein) (hPRP8BP) (U5 snRNP-specific 40 kDa protein) (WD repeat-containing protein 57) | SNRNP40 | mRNA splicing, via spliceosome [GO:0000398]; RNA processing [GO:0006396]; RNA splicing [GO:0008380]; RNA splicing, via transesterification reactions [GO:0000375] | catalytic step 2 spliceosome [GO:0071013]; cytosol [GO:0005829]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; sno(s)RNA-containing ribonucleoprotein complex [GO:0005732]; U2-type catalytic step 2 spliceosome [GO:0071007]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682] | RNA binding [GO:0003723] | 11497.49182943015 | 0.0793673452699615 | 0.82954941847346 | 1 |
| P09012 | P09012 | SNRPA_HUMAN | U1 small nuclear ribonucleoprotein A (U1 snRNP A) (U1-A) (U1A) | SNRPA | mRNA splicing, via spliceosome [GO:0000398] | nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spliceosomal complex [GO:0005681]; U1 snRNP [GO:0005685]; U4/U6 x U5 tri-snRNP complex [GO:0046540] | DNA binding [GO:0003677]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; U1 snRNA binding [GO:0030619]; U1 snRNP binding [GO:1990446] | 43641.755033616 | 0.135799342351177 | 0.839108213965648 | 1 |
| Q13425 | Q13425 | SNTB2_HUMAN | Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin-3) (SNT3) (Syntrophin-like) (SNTL) | SNTB2 | cytoplasm [GO:0005737]; dystrophin-associated glycoprotein complex [GO:0016010]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; synapse [GO:0045202]; transport vesicle membrane [GO:0030658] | actin binding [GO:0003779]; calmodulin binding [GO:0005516]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198] | 17922.495832366098 | 0.00318379660847704 | 0.999999698978976 | 1 | |
| Q13573 | Q13573 | SNW1_HUMAN | SNW domain-containing protein 1 (Nuclear protein SkiP) (Nuclear receptor coactivator NCoA-62) (Ski-interacting protein) | SNW1 | cellular response to retinoic acid [GO:0071300]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; positive regulation of neurogenesis [GO:0050769]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of vitamin D receptor signaling pathway [GO:0070564]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of vitamin D receptor signaling pathway [GO:0070562]; retinoic acid receptor signaling pathway [GO:0048384] | catalytic step 2 spliceosome [GO:0071013]; nuclear body [GO:0016604]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spliceosomal complex [GO:0005681]; U2-type catalytic step 2 spliceosome [GO:0071007] | enzyme binding [GO:0019899]; Notch binding [GO:0005112]; nuclear androgen receptor binding [GO:0050681]; nuclear receptor binding [GO:0016922]; nuclear retinoic acid receptor binding [GO:0042974]; nuclear vitamin D receptor binding [GO:0042809]; RNA binding [GO:0003723]; SMAD binding [GO:0046332]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714] | 17425.3781935285 | 0.0930710015474869 | 0.922888290802782 | 1 |
| Q9UMY4 | Q9UMY4 | SNX12_HUMAN | Sorting nexin-12 | SNX12 | endocytic recycling [GO:0032456]; late endosome to Golgi transport [GO:0034499]; negative regulation of early endosome to late endosome transport [GO:2000642]; negative regulation of gene expression [GO:0010629]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein processing [GO:0010955]; negative regulation of protein transport [GO:0051224]; protein transport [GO:0015031]; regulation of endocytosis [GO:0030100] | early endosome [GO:0005769]; early endosome membrane [GO:0031901]; retromer complex [GO:0030904] | enzyme binding [GO:0019899]; phosphatidylinositol binding [GO:0035091]; phosphatidylinositol-3-phosphate binding [GO:0032266] | 31429.470123391548 | 0.0785246099548553 | 0.926259788353192 | 1 |
| O60749 | O60749 | SNX2_HUMAN | Sorting nexin-2 (Transformation-related gene 9 protein) (TRG-9) | SNX2 | early endosome to Golgi transport [GO:0034498]; intracellular protein transport [GO:0006886]; lamellipodium morphogenesis [GO:0072673]; retrograde transport, endosome to Golgi [GO:0042147] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome membrane [GO:0031901]; endosome [GO:0005768]; endosome membrane [GO:0010008]; lamellipodium [GO:0030027]; lysosome [GO:0005764]; membrane [GO:0016020]; protein-containing complex [GO:0032991]; retromer complex [GO:0030904]; retromer, tubulation complex [GO:0030905] | cadherin binding [GO:0045296]; epidermal growth factor receptor binding [GO:0005154]; identical protein binding [GO:0042802]; insulin receptor binding [GO:0005158]; leptin receptor binding [GO:1990460]; phosphatidylinositol binding [GO:0035091]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; transferrin receptor binding [GO:1990459] | 53417.7960319373 | -0.00650529574684678 | 0.999999994049137 | 1 |
| Q5VWJ9 | Q5VWJ9 | SNX30_HUMAN | Sorting nexin-30 | SNX30 | endocytic recycling [GO:0032456]; piecemeal microautophagy of the nucleus [GO:0034727]; positive regulation of autophagosome assembly [GO:2000786]; protein transport [GO:0015031]; reticulophagy [GO:0061709] | early endosome [GO:0005769]; early endosome membrane [GO:0031901]; phagophore assembly site [GO:0000407] | phosphatidylinositol binding [GO:0035091] | 10519.9658966838 | -0.0812799257803915 | 0.919370206731314 | 1 |
| Q8WV41 | Q8WV41 | SNX33_HUMAN | Sorting nexin-33 (SH3 and PX domain-containing protein 3) | SNX33 | cleavage furrow formation [GO:0036089]; endocytosis [GO:0006897]; endosomal transport [GO:0016197]; endosome organization [GO:0007032]; intracellular protein transport [GO:0006886]; macropinocytosis [GO:0044351]; mitotic cytokinesis [GO:0000281]; negative regulation of endocytosis [GO:0045806]; negative regulation of protein localization to cell surface [GO:2000009]; plasma membrane tubulation [GO:0097320]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of protein localization to cell surface [GO:2000010]; protein import [GO:0017038] | cytoplasmic vesicle [GO:0031410]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886] | identical protein binding [GO:0042802]; phosphatidylinositol binding [GO:0035091] | 8855.45860207899 | 0.102035746098951 | 0.950202287150988 | 1 |
| Q9Y5X3 | Q9Y5X3 | SNX5_HUMAN | Sorting nexin-5 | SNX5 | epidermal growth factor catabolic process [GO:0007174]; intracellular protein transport [GO:0006886]; negative regulation of blood pressure [GO:0045776]; pinocytosis [GO:0006907]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of insulin receptor signaling pathway [GO:0046628]; regulation of macroautophagy [GO:0016241]; retrograde transport, endosome to Golgi [GO:0042147] | brush border [GO:0005903]; cytoplasmic side of early endosome membrane [GO:0098559]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; endosome [GO:0005768]; intracellular membrane-bounded organelle [GO:0043231]; macropinocytic cup [GO:0070685]; perinuclear region of cytoplasm [GO:0048471]; phagocytic cup [GO:0001891]; retromer complex [GO:0030904]; retromer, tubulation complex [GO:0030905]; ruffle [GO:0001726]; tubular endosome [GO:0097422] | cadherin binding [GO:0045296]; D1 dopamine receptor binding [GO:0031748]; dynactin binding [GO:0034452]; phosphatidylinositol binding [GO:0035091]; phosphatidylinositol-3,5-bisphosphate binding [GO:0080025]; phosphatidylinositol-4-phosphate binding [GO:0070273]; phosphatidylinositol-5-phosphate binding [GO:0010314] | 21703.8888318143 | -0.0908440544303647 | 0.657866025447785 | 1 |
| Q9Y5X2 | Q9Y5X2 | SNX8_HUMAN | Sorting nexin-8 | SNX8 | early endosome to Golgi transport [GO:0034498]; intracellular protein transport [GO:0006886] | cytosol [GO:0005829]; early endosome membrane [GO:0031901]; intracellular membrane-bounded organelle [GO:0043231] | identical protein binding [GO:0042802]; phosphatidylinositol binding [GO:0035091] | 8233.893184694505 | 0.0804684387275116 | 0.657965163843578 | 1 |
| P18583 | P18583 | SON_HUMAN | Protein SON (Bax antagonist selected in saccharomyces 1) (BASS1) (Negative regulatory element-binding protein) (NRE-binding protein) (Protein DBP-5) (SON3) | SON | microtubule cytoskeleton organization [GO:0000226]; mitotic cytokinesis [GO:0000281]; mRNA processing [GO:0006397]; negative regulation of apoptotic process [GO:0043066]; regulation of cell cycle [GO:0051726]; regulation of mRNA splicing, via spliceosome [GO:0048024]; regulation of RNA splicing [GO:0043484]; RNA splicing [GO:0008380] | nuclear speck [GO:0016607] | DNA binding [GO:0003677]; RNA binding [GO:0003723] | 11973.816571094001 | -0.115710612411517 | 0.947086353816403 | 1 |
| P09486 | P09486 | SPRC_HUMAN | SPARC (Basement-membrane protein 40) (BM-40) (Osteonectin) (ON) (Secreted protein acidic and rich in cysteine) | SPARC | negative regulation of angiogenesis [GO:0016525]; negative regulation of endothelial cell proliferation [GO:0001937]; positive regulation of endothelial cell migration [GO:0010595]; regulation of cell morphogenesis [GO:0022604] | basement membrane [GO:0005604]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; endocytic vesicle lumen [GO:0071682]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; nuclear matrix [GO:0016363]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; platelet alpha granule membrane [GO:0031092] | calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; extracellular matrix binding [GO:0050840] | 210293.107858904 | -0.0718804978452632 | 0.999999999289816 | 1 |
| Q9UBP0 | Q9UBP0 | SPAST_HUMAN | Spastin (EC 5.6.1.1) (Spastic paraplegia 4 protein) | SPAST | anterograde axonal transport [GO:0008089]; axonal transport of mitochondrion [GO:0019896]; axonogenesis [GO:0007409]; cytokinetic process [GO:0032506]; cytoskeleton-dependent cytokinesis [GO:0061640]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exit from mitosis [GO:0010458]; membrane fission [GO:0090148]; metabolic process [GO:0008152]; microtubule bundle formation [GO:0001578]; microtubule severing [GO:0051013]; mitotic cytokinesis [GO:0000281]; mitotic nuclear membrane reassembly [GO:0007084]; mitotic spindle disassembly [GO:0051228]; nuclear membrane reassembly [GO:0031468]; positive regulation of cytokinesis [GO:0032467]; positive regulation of microtubule depolymerization [GO:0031117]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260] | axon [GO:0030424]; axon cytoplasm [GO:1904115]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum tubular network [GO:0071782]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; lipid droplet [GO:0005811]; microtubule [GO:0005874]; midbody [GO:0030496]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; spindle pole [GO:0000922] | alpha-tubulin binding [GO:0043014]; ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; beta-tubulin binding [GO:0048487]; isomerase activity [GO:0016853]; microtubule binding [GO:0008017]; microtubule severing ATPase activity [GO:0008568]; protein-containing complex binding [GO:0044877] | 6022.98948678972 | -0.0932906087656001 | 0.84937535013872 | 1 |
| Q8TB22 | Q8TB22 | SPT20_HUMAN | Spermatogenesis-associated protein 20 (Sperm-specific protein 411) (Ssp411) | SPATA20 | carbohydrate metabolic process [GO:0005975]; cell differentiation [GO:0030154]; spermatogenesis [GO:0007283] | extracellular region [GO:0005576] | 13366.479642061699 | -0.175082585687086 | 0.792285460467847 | 1 | |
| Q9Y6A9 | Q9Y6A9 | SPCS1_HUMAN | Signal peptidase complex subunit 1 (Microsomal signal peptidase 12 kDa subunit) (SPase 12 kDa subunit) | SPCS1 | protein targeting to ER [GO:0045047]; proteolysis [GO:0006508]; signal peptide processing [GO:0006465]; viral protein processing [GO:0019082]; virion assembly [GO:0019068] | endoplasmic reticulum membrane [GO:0005789]; signal peptidase complex [GO:0005787] | 175212.4827752335 | -0.0595602227759521 | 0.977135369635525 | 1 | |
| Q15005 | Q15005 | SPCS2_HUMAN | Signal peptidase complex subunit 2 (Microsomal signal peptidase 25 kDa subunit) (SPase 25 kDa subunit) | SPCS2 | protein targeting to ER [GO:0045047]; signal peptide processing [GO:0006465] | endoplasmic reticulum membrane [GO:0005789]; signal peptidase complex [GO:0005787] | 184421.45276979648 | 0.0522309696800253 | 0.941690184107288 | 1 | |
| P61009 | P61009 | SPCS3_HUMAN | Signal peptidase complex subunit 3 (Microsomal signal peptidase 22/23 kDa subunit) (SPC22/23) (SPase 22/23 kDa subunit) | SPCS3 | protein targeting to ER [GO:0045047]; proteolysis [GO:0006508]; signal peptide processing [GO:0006465]; viral protein processing [GO:0019082] | endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; signal peptidase complex [GO:0005787] | 148065.63704001548 | 0.0987747498144045 | 0.739116443615434 | 1 | |
| Q13813 | Q13813 | SPTN1_HUMAN | Spectrin alpha chain, non-erythrocytic 1 (Alpha-II spectrin) (Fodrin alpha chain) (Spectrin, non-erythroid alpha subunit) | SPTAN1 | actin cytoskeleton organization [GO:0030036]; actin filament capping [GO:0051693] | cell junction [GO:0030054]; cell projection [GO:0042995]; cortical actin cytoskeleton [GO:0030864]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular vesicle [GO:1903561]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; microtubule cytoskeleton [GO:0015630]; plasma membrane [GO:0005886]; specific granule lumen [GO:0035580]; spectrin [GO:0008091]; tertiary granule lumen [GO:1904724] | actin binding [GO:0003779]; actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; structural constituent of cytoskeleton [GO:0005200] | 78724.8161095894 | -0.0882691086036265 | 0.999999927125088 | 1 |
| Q01082 | Q01082 | SPTB2_HUMAN | Spectrin beta chain, non-erythrocytic 1 (Beta-II spectrin) (Fodrin beta chain) (Spectrin, non-erythroid beta chain 1) | SPTBN1 | actin cytoskeleton organization [GO:0030036]; actin filament capping [GO:0051693]; central nervous system development [GO:0007417]; central nervous system formation [GO:0021556]; Golgi to plasma membrane protein transport [GO:0043001]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; plasma membrane organization [GO:0007009]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of protein localization to plasma membrane [GO:1903078]; protein localization to plasma membrane [GO:0072659]; regulation of protein localization to plasma membrane [GO:1903076]; regulation of SMAD protein signal transduction [GO:0060390] | axolemma [GO:0030673]; cell junction [GO:0030054]; cell projection [GO:0042995]; cortical actin cytoskeleton [GO:0030864]; cuticular plate [GO:0032437]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; M band [GO:0031430]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; spectrin [GO:0008091]; spectrin-associated cytoskeleton [GO:0014731] | actin binding [GO:0003779]; actin filament binding [GO:0051015]; ankyrin binding [GO:0030506]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; GTPase binding [GO:0051020]; phospholipid binding [GO:0005543]; RNA binding [GO:0003723]; structural constituent of cytoskeleton [GO:0005200] | 93363.79823178834 | -0.0560466609841626 | 0.999999998972845 | 1 |
| Q14534 | Q14534 | ERG1_HUMAN | Squalene monooxygenase (EC 1.14.14.17) (Squalene epoxidase) (SE) | SQLE | cholesterol metabolic process [GO:0008203]; ergosterol biosynthetic process [GO:0006696]; lipid droplet formation [GO:0140042]; regulation of cell population proliferation [GO:0042127]; response to organic substance [GO:0010033]; sterol biosynthetic process [GO:0016126] | endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020] | FAD binding [GO:0071949]; squalene monooxygenase activity [GO:0004506] | 9408.164211673515 | -0.0161947055737433 | 0.999999999235719 | 1 |
| Q7Z6B7 | Q7Z6B7 | SRGP1_HUMAN | SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho GTPase-activating protein 13) | SRGAP1 | negative regulation of cell migration [GO:0030336]; signal transduction [GO:0007165] | cytoplasm [GO:0005737]; cytosol [GO:0005829] | GTPase activator activity [GO:0005096] | 8662.84248520738 | -0.0487507635434333 | 0.979126196293019 | 1 |
| P10124 | P10124 | SRGN_HUMAN | Serglycin (Hematopoietic proteoglycan core protein) (Platelet proteoglycan core protein) (P.PG) (Secretory granule proteoglycan core protein) | SRGN | apoptotic process [GO:0006915]; biomineral tissue development [GO:0031214]; granzyme-mediated programmed cell death signaling pathway [GO:0140507]; maintenance of granzyme B location in T cell secretory granule [GO:0033382]; maintenance of protease location in mast cell secretory granule [GO:0033373]; mast cell secretory granule organization [GO:0033364]; negative regulation of bone mineralization [GO:0030502]; negative regulation of cytokine production [GO:0001818]; protein processing [GO:0016485]; secretory granule organization [GO:0033363]; T cell secretory granule organization [GO:0033371] | cytolytic granule [GO:0044194]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; mast cell granule [GO:0042629]; platelet alpha granule lumen [GO:0031093]; secretory granule [GO:0030141] | 12641.987484468049 | -0.321845250106125 | 0.991680872776033 | 1 | |
| P61011 | P61011 | SRP54_HUMAN | Signal recognition particle subunit SRP54 (EC 3.6.5.4) (Signal recognition particle 54 kDa protein) | SRP54 | exocrine pancreas development [GO:0031017]; granulocyte differentiation [GO:0030851]; neutrophil chemotaxis [GO:0030593]; protein targeting to ER [GO:0045047]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]; SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition [GO:0006617]; SRP-dependent cotranslational protein targeting to membrane, translocation [GO:0006616] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; nuclear speck [GO:0016607]; nucleus [GO:0005634]; signal recognition particle, endoplasmic reticulum targeting [GO:0005786] | 7S RNA binding [GO:0008312]; ATP hydrolysis activity [GO:0016887]; endoplasmic reticulum signal peptide binding [GO:0030942]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; ribonucleoprotein complex binding [GO:0043021]; RNA binding [GO:0003723] | 32934.326427135704 | 0.0869286632010554 | 0.795794175622949 | 1 |
| Q9UHB9 | Q9UHB9 | SRP68_HUMAN | Signal recognition particle subunit SRP68 (SRP68) (Signal recognition particle 68 kDa protein) | SRP68 | response to xenobiotic stimulus [GO:0009410]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614] | cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; focal adhesion [GO:0005925]; nucleolus [GO:0005730]; ribosome [GO:0005840]; signal recognition particle [GO:0048500]; signal recognition particle, endoplasmic reticulum targeting [GO:0005786] | 7S RNA binding [GO:0008312]; endoplasmic reticulum signal peptide binding [GO:0030942]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; signal recognition particle binding [GO:0005047] | 33765.23016255681 | -0.0720197686499137 | 0.756359150304943 | 1 |
| O76094 | O76094 | SRP72_HUMAN | Signal recognition particle subunit SRP72 (SRP72) (Signal recognition particle 72 kDa protein) | SRP72 | SRP-dependent cotranslational protein targeting to membrane [GO:0006614] | cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; signal recognition particle [GO:0048500]; signal recognition particle, endoplasmic reticulum targeting [GO:0005786] | 7S RNA binding [GO:0008312]; ribosome binding [GO:0043022]; RNA binding [GO:0003723]; signal recognition particle binding [GO:0005047]; TPR domain binding [GO:0030911] | 49916.00562912105 | 0.0232938632746572 | 0.999902309231211 | 1 |
| Q8IYB3 | Q8IYB3 | SRRM1_HUMAN | Serine/arginine repetitive matrix protein 1 (SR-related nuclear matrix protein of 160 kDa) (SRm160) (Ser/Arg-related nuclear matrix protein) | SRRM1 | localization [GO:0051179]; mRNA splicing, via spliceosome [GO:0000398]; regulation of mRNA splicing, via spliceosome [GO:0048024]; RNA splicing [GO:0008380]; RNA splicing, via transesterification reactions [GO:0000375] | catalytic step 2 spliceosome [GO:0071013]; cytosol [GO:0005829]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spliceosomal complex [GO:0005681] | DNA binding [GO:0003677]; RNA binding [GO:0003723] | 25506.712341677397 | -0.0654314810311232 | 0.876425083274325 | 1 |
| Q9UQ35 | Q9UQ35 | SRRM2_HUMAN | Serine/arginine repetitive matrix protein 2 (300 kDa nuclear matrix antigen) (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (SR-related nuclear matrix protein of 300 kDa) (Ser/Arg-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (Tax-responsive enhancer element-binding protein 803) (TaxREB803) | SRRM2 | mRNA splicing, via spliceosome [GO:0000398] | Cajal body [GO:0015030]; catalytic step 2 spliceosome [GO:0071013]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; U2-type catalytic step 2 spliceosome [GO:0071007]; U2-type precatalytic spliceosome [GO:0071005] | C2H2 zinc finger domain binding [GO:0070742]; mRNA binding [GO:0003729]; RNA binding [GO:0003723] | 21856.5910664851 | -0.08496900347238 | 0.959562187281048 | 1 |
| Q9BXP5 | Q9BXP5 | SRRT_HUMAN | Serrate RNA effector molecule homolog (Arsenite-resistance protein 2) | SRRT | mRNA processing [GO:0006397]; neuronal stem cell population maintenance [GO:0097150]; positive regulation of neurogenesis [GO:0050769]; primary miRNA processing [GO:0031053]; regulation of DNA-templated transcription [GO:0006355]; response to arsenic-containing substance [GO:0046685] | cytoplasm [GO:0005737]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904] | DNA binding [GO:0003677]; mRNA cap binding complex binding [GO:0140262]; protein-macromolecule adaptor activity [GO:0030674]; RNA binding [GO:0003723] | 13528.07135535735 | 0.0109819956157521 | 0.999999998903718 | 1 |
| Q08170 | Q08170 | SRSF4_HUMAN | Serine/arginine-rich splicing factor 4 (Pre-mRNA-splicing factor SRP75) (SRP001LB) (Splicing factor, arginine/serine-rich 4) | SRSF4 | mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; response to insulin [GO:0032868]; RNA splicing [GO:0008380]; RNA splicing, via transesterification reactions [GO:0000375] | cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] | RNA binding [GO:0003723]; sequence-specific mRNA binding [GO:1990825] | 16548.90526619985 | 0.248265958681361 | 0.78432158784842 | 1 |
| Q9BYN0 | Q9BYN0 | SRXN1_HUMAN | Sulfiredoxin-1 (EC 1.8.98.2) | SRXN1 | cellular response to oxidative stress [GO:0034599]; response to oxidative stress [GO:0006979] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789] | ATP binding [GO:0005524]; oxidoreductase activity, acting on a sulfur group of donors [GO:0016667]; sulfiredoxin activity [GO:0032542] | 19141.77314823735 | -0.118634147727206 | 0.871795915519312 | 1 |
| P05455 | P05455 | LA_HUMAN | Lupus La protein (La autoantigen) (La ribonucleoprotein) (Sjoegren syndrome type B antigen) (SS-B) | SSB | histone mRNA metabolic process [GO:0008334]; IRES-dependent viral translational initiation [GO:0075522]; nuclear histone mRNA catabolic process [GO:0071045]; positive regulation of translation [GO:0045727]; protein localization to cytoplasmic stress granule [GO:1903608]; tRNA 3'-end processing [GO:0042780]; tRNA 5'-leader removal [GO:0001682]; tRNA export from nucleus [GO:0006409]; tRNA modification [GO:0006400]; tRNA processing [GO:0008033] | chromosome, telomeric region [GO:0000781]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904] | mRNA binding [GO:0003729]; poly(U) RNA binding [GO:0008266]; RNA binding [GO:0003723]; sequence-specific mRNA binding [GO:1990825]; tRNA binding [GO:0000049] | 50818.5934709268 | 0.18849689001255 | 0.748625271182431 | 1 |
| Q8TE77 | Q8TE77 | SSH3_HUMAN | Protein phosphatase Slingshot homolog 3 (EC 3.1.3.16) (EC 3.1.3.48) (SSH-like protein 3) (SSH-3L) (hSSH-3L) | SSH3 | actin cytoskeleton organization [GO:0030036]; dephosphorylation [GO:0016311]; negative regulation of actin filament polymerization [GO:0030837] | cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; nucleus [GO:0005634] | actin binding [GO:0003779]; myosin phosphatase activity [GO:0017018]; phosphoprotein phosphatase activity [GO:0004721]; protein tyrosine phosphatase activity [GO:0004725]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138] | 7464.246423633245 | 0.0661198166834663 | 0.698316014089321 | 1 |
| Q8NFI4 | Q8NFI4 | F10A5_HUMAN | Putative protein FAM10A5 (Suppression of tumorigenicity 13 pseudogene 5) | ST13P5 | chaperone cofactor-dependent protein refolding [GO:0051085] | cytoplasm [GO:0005737] | Hsp70 protein binding [GO:0030544]; protein dimerization activity [GO:0046983] | 37395.119409672145 | -0.46073193032278 | 0.894524709021104 | 1 |
| Q9NRC1 | Q9NRC1 | ST7_HUMAN | Suppressor of tumorigenicity 7 protein (Protein FAM4A1) (Protein HELG) | ST7 | extracellular matrix organization [GO:0030198]; regulation of cell differentiation [GO:0045595] | membrane [GO:0016020] | 2535.49467940844 | 0.0363631996901059 | 0.993889270711568 | 1 | |
| Q8N3U4 | Q8N3U4 | STAG2_HUMAN | Cohesin subunit SA-2 (SCC3 homolog 2) (Stromal antigen 2) | STAG2 | cell division [GO:0051301]; establishment of mitotic sister chromatid cohesion [GO:0034087]; meiotic cell cycle [GO:0051321]; mitotic spindle assembly [GO:0090307]; sister chromatid cohesion [GO:0007062] | chromatin [GO:0000785]; chromosome [GO:0005694]; chromosome, centromeric region [GO:0000775]; cohesin complex [GO:0008278]; cytosol [GO:0005829]; fibrillar center [GO:0001650]; membrane [GO:0016020]; mitotic cohesin complex [GO:0030892]; mitotic spindle pole [GO:0097431]; nuclear matrix [GO:0016363]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] | chromatin binding [GO:0003682] | 6620.000172588435 | -0.32704691496194 | 0.695592511375458 | 1 |
| Q92783 | Q92783 | STAM1_HUMAN | Signal transducing adapter molecule 1 (STAM-1) | STAM | macroautophagy [GO:0016236]; membrane fission [GO:0090148]; multivesicular body assembly [GO:0036258]; positive regulation of exosomal secretion [GO:1903543]; protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043328]; regulation of extracellular exosome assembly [GO:1903551]; signal transduction [GO:0007165] | cytosol [GO:0005829]; early endosome membrane [GO:0031901]; ESCRT-0 complex [GO:0033565]; intracellular membrane-bounded organelle [GO:0043231] | phosphatidylinositol binding [GO:0035091]; ubiquitin binding [GO:0043130]; ubiquitin-like protein ligase binding [GO:0044389] | 29948.0949389834 | 0.0463800432082918 | 0.952862734686889 | 1 |
| O75886 | O75886 | STAM2_HUMAN | Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein) | STAM2 | macroautophagy [GO:0016236]; membrane fission [GO:0090148]; multivesicular body assembly [GO:0036258]; protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043328]; signal transduction [GO:0007165] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; ESCRT-0 complex [GO:0033565]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654] | phosphatidylinositol binding [GO:0035091]; ubiquitin binding [GO:0043130] | 26434.4128452589 | 0.13509545942909 | 0.68958041402813 | 1 |
| O95630 | O95630 | STABP_HUMAN | STAM-binding protein (EC 3.4.19.-) (Associated molecule with the SH3 domain of STAM) (Endosome-associated ubiquitin isopeptidase) | STAMBP | hippocampal neuron apoptotic process [GO:0110088]; mitotic cytokinesis [GO:0000281]; negative regulation of hippocampal neuron apoptotic process [GO:0110091]; negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction [GO:0051898]; negative regulation of Ras protein signal transduction [GO:0046580]; positive regulation of cell population proliferation [GO:0008284]; protein deubiquitination [GO:0016579]; proteolysis [GO:0006508]; receptor signaling pathway via JAK-STAT [GO:0007259] | cleavage furrow [GO:0032154]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886] | deubiquitinase activity [GO:0101005]; K63-linked deubiquitinase activity [GO:0061578]; metal ion binding [GO:0046872]; metal-dependent deubiquitinase activity [GO:0140492]; protein domain specific binding [GO:0019904] | 7723.22510307375 | 0.126402405585964 | 0.748174497667972 | 1 |
| Q9Y3M8 | Q9Y3M8 | STA13_HUMAN | StAR-related lipid transfer protein 13 (46H23.2) (Deleted in liver cancer 2 protein) (DLC-2) (Rho GTPase-activating protein) (START domain-containing protein 13) (StARD13) | STARD13 | actin cytoskeleton organization [GO:0030036]; endothelial cell migration [GO:0043542]; endothelial tube lumen extension [GO:0097498]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165] | cytosol [GO:0005829]; lipid droplet [GO:0005811]; mitochondrial membrane [GO:0031966] | GTPase activator activity [GO:0005096]; lipid binding [GO:0008289] | 6975.76498639668 | -0.0321894392263083 | 0.865539047819972 | 1 |
| O95210 | O95210 | STBD1_HUMAN | Starch-binding domain-containing protein 1 (Genethonin-1) (Glycophagy cargo receptor STBD1) | STBD1 | glycogen catabolic process [GO:0005980]; glycophagy [GO:0061723]; intracellular transport [GO:0046907]; substrate localization to autophagosome [GO:0061753] | endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; ficolin-1-rich granule membrane [GO:0101003]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; phagophore assembly site membrane [GO:0034045]; plasma membrane [GO:0005886]; T-tubule [GO:0030315]; tertiary granule membrane [GO:0070821] | cargo receptor activity [GO:0038024]; enzyme binding [GO:0019899]; glycogen binding [GO:2001069]; polysaccharide binding [GO:0030247]; starch binding [GO:2001070] | 18574.9636902032 | -0.0730125164873232 | 0.67253620326138 | 1 |
| O76061 | O76061 | STC2_HUMAN | Stanniocalcin-2 (STC-2) (Stanniocalcin-related protein) (STC-related protein) (STCRP) | STC2 | cellular response to hypoxia [GO:0071456]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; endoplasmic reticulum unfolded protein response [GO:0030968]; intracellular calcium ion homeostasis [GO:0006874]; negative regulation of gene expression [GO:0010629]; negative regulation of multicellular organism growth [GO:0040015]; regulation of hormone biosynthetic process [GO:0046885]; regulation of store-operated calcium entry [GO:2001256]; response to oxidative stress [GO:0006979]; response to peptide hormone [GO:0043434]; response to vitamin D [GO:0033280] | endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; perinuclear region of cytoplasm [GO:0048471] | enzyme binding [GO:0019899]; heme binding [GO:0020037]; hormone activity [GO:0005179]; protein homodimerization activity [GO:0042803] | 4399.8900992710405 | -0.0412172080541307 | 0.961362003644332 | 1 |
| Q658P3 | Q658P3 | STEA3_HUMAN | Metalloreductase STEAP3 (EC 1.16.1.-) (Dudulin-2) (Six-transmembrane epithelial antigen of prostate 3) (Tumor suppressor-activated pathway protein 6) (hTSAP6) (pHyde) (hpHyde) | STEAP3 | apoptotic process [GO:0006915]; cell cycle [GO:0007049]; copper ion import [GO:0015677]; protein secretion [GO:0009306]; transferrin transport [GO:0033572] | cytoplasm [GO:0005737]; endosome [GO:0005768]; endosome membrane [GO:0010008]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886] | cupric reductase activity [GO:0008823]; FAD binding [GO:0071949]; ferric-chelate reductase (NADPH) activity [GO:0052851]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on metal ions, NAD or NADP as acceptor [GO:0016723] | 5557.162981760435 | -0.060091052236431 | 0.968343971141056 | 1 |
| Q9P246 | Q9P246 | STIM2_HUMAN | Stromal interaction molecule 2 | STIM2 | activation of store-operated calcium channel activity [GO:0032237]; intracellular calcium ion homeostasis [GO:0006874]; positive regulation of calcium ion transport [GO:0051928]; store-operated calcium entry [GO:0002115] | endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; plasma membrane [GO:0005886] | calcium channel regulator activity [GO:0005246]; calcium ion binding [GO:0005509]; store-operated calcium channel activity [GO:0015279] | 1279.984613178865 | 0.571016836011885 | 0.812614583988087 | 1 |
| Q86WV6 | Q86WV6 | STING_HUMAN | Stimulator of interferon genes protein (hSTING) (Endoplasmic reticulum interferon stimulator) (ERIS) (Mediator of IRF3 activation) (hMITA) (Transmembrane protein 173) | STING1 | activation of innate immune response [GO:0002218]; antiviral innate immune response [GO:0140374]; autophagosome assembly [GO:0000045]; cellular response to exogenous dsRNA [GO:0071360]; cellular response to interferon-beta [GO:0035458]; cellular response to organic cyclic compound [GO:0071407]; cGAS/STING signaling pathway [GO:0140896]; cytoplasmic pattern recognition receptor signaling pathway [GO:0002753]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; pattern recognition receptor signaling pathway [GO:0002221]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of macroautophagy [GO:0016239]; positive regulation of protein binding [GO:0032092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein complex oligomerization [GO:0051259]; protein localization to endoplasmic reticulum [GO:0070972]; regulation of inflammatory response [GO:0050727]; reticulophagy [GO:0061709] | autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; endosome [GO:0005768]; Golgi membrane [GO:0000139]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; peroxisome [GO:0005777]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; serine/threonine protein kinase complex [GO:1902554]; STING complex [GO:1990231] | 2',3'-cyclic GMP-AMP binding [GO:0061507]; cyclic-di-GMP binding [GO:0035438]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; proton channel activity [GO:0015252]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; signaling adaptor activity [GO:0035591]; ubiquitin protein ligase binding [GO:0031625] | 17844.542497819202 | -0.0864250925352029 | 0.896303327229182 | 1 |
| Q9Y6E0 | Q9Y6E0 | STK24_HUMAN | Serine/threonine-protein kinase 24 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 3) (MST-3) (STE20-like kinase MST3) [Cleaved into: Serine/threonine-protein kinase 24 36 kDa subunit (Mammalian STE20-like protein kinase 3 N-terminal) (MST3/N); Serine/threonine-protein kinase 24 12 kDa subunit (Mammalian STE20-like protein kinase 3 C-terminal) (MST3/C)] | STK24 | cellular response to oxidative stress [GO:0034599]; cellular response to starvation [GO:0009267]; execution phase of apoptosis [GO:0097194]; intrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631]; negative regulation of cell migration [GO:0030336]; positive regulation of axon regeneration [GO:0048680]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of axon regeneration [GO:0048679]; signal transduction [GO:0007165] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] | ATP binding [GO:0005524]; cadherin binding [GO:0045296]; metal ion binding [GO:0046872]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] | 18683.24774803715 | 0.0330718477755626 | 0.997244648701167 | 1 |
| O00506 | O00506 | STK25_HUMAN | Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Ste20-like kinase) (Sterile 20/oxidant stress-response kinase 1) (SOK-1) (Ste20/oxidant stress response kinase 1) | STK25 | axonogenesis [GO:0007409]; cellular response to oxidative stress [GO:0034599]; establishment of Golgi localization [GO:0051683]; establishment or maintenance of cell polarity [GO:0007163]; Golgi localization [GO:0051645]; Golgi reassembly [GO:0090168]; intrinsic apoptotic signaling pathway in response to hydrogen peroxide [GO:0036481]; positive regulation of axonogenesis [GO:0050772]; positive regulation of stress-activated MAPK cascade [GO:0032874]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; response to oxidative stress [GO:0006979]; signal transduction [GO:0007165] | cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794] | ATP binding [GO:0005524]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] | 11204.7041070727 | -0.00670383587016304 | 0.984139186816445 | 1 |
| Q9P289 | Q9P289 | STK26_HUMAN | Serine/threonine-protein kinase 26 (EC 2.7.11.1) (MST3 and SOK1-related kinase) (Mammalian STE20-like protein kinase 4) (MST-4) (STE20-like kinase MST4) (Serine/threonine-protein kinase MASK) | STK26 | apoptotic process [GO:0006915]; cellular response to oxidative stress [GO:0034599]; cellular response to starvation [GO:0009267]; intracellular signal transduction [GO:0035556]; microvillus assembly [GO:0030033]; negative regulation of cell migration [GO:0030336]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of apoptotic process [GO:0042981] | apical plasma membrane [GO:0016324]; cell periphery [GO:0071944]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle [GO:0005798]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; vesicle membrane [GO:0012506] | ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] | 4124.97803067373 | 0.0586368681106313 | 0.77822652422918 | 1 |
| Q13188 | Q13188 | STK3_HUMAN | Serine/threonine-protein kinase 3 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 2) (MST-2) (STE20-like kinase MST2) (Serine/threonine-protein kinase Krs-1) [Cleaved into: Serine/threonine-protein kinase 3 36kDa subunit (MST2/N); Serine/threonine-protein kinase 3 20kDa subunit (MST2/C)] | STK3 | apoptotic process [GO:0006915]; canonical Wnt signaling pathway [GO:0060070]; cell differentiation involved in embryonic placenta development [GO:0060706]; central nervous system development [GO:0007417]; endocardium development [GO:0003157]; epithelial cell proliferation [GO:0050673]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; hepatocyte apoptotic process [GO:0097284]; hippo signaling [GO:0035329]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of organ growth [GO:0046621]; neural tube formation [GO:0001841]; organ growth [GO:0035265]; phosphatidylinositol 3-kinase/protein kinase B signal transduction [GO:0043491]; positive regulation of apoptotic process [GO:0043065]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902043]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of JNK cascade [GO:0046330]; positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction [GO:0051897]; positive regulation of protein binding [GO:0032092]; primitive hemopoiesis [GO:0060215]; protein import into nucleus [GO:0006606]; protein localization to centrosome [GO:0071539]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; regulation of cell differentiation involved in embryonic placenta development [GO:0060800]; regulation of MAPK cascade [GO:0043408] | centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; protein-containing complex [GO:0032991] | ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activator activity [GO:0043539]; protein serine/threonine kinase activity [GO:0004674] | 8490.860797097524 | 0.0225370100198581 | 0.976179423331982 | 1 |
| P27105 | P27105 | STOM_HUMAN | Stomatin (Erythrocyte band 7 integral membrane protein) (Erythrocyte membrane protein band 7.2) (Protein 7.2b) | STOM | positive regulation by host of viral genome replication [GO:0044829]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of viral process [GO:0048524]; regulation of monoatomic ion transmembrane transport [GO:0034765] | azurophil granule membrane [GO:0035577]; blood microparticle [GO:0072562]; cytoskeleton [GO:0005856]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; melanosome [GO:0042470]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; vesicle [GO:0031982] | identical protein binding [GO:0042802]; ion channel inhibitor activity [GO:0008200]; protein homodimerization activity [GO:0042803]; RNA polymerase binding [GO:0070063] | 53761.9583705654 | -0.0447710383168818 | 0.916055110947349 | 1 |
| Q5VSL9 | Q5VSL9 | STRP1_HUMAN | Striatin-interacting protein 1 (Protein FAM40A) | STRIP1 | cortical actin cytoskeleton organization [GO:0030866]; cytoskeleton organization [GO:0007010]; regulation of cell morphogenesis [GO:0022604] | cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleus [GO:0005634] | protein kinase binding [GO:0019901]; small GTPase binding [GO:0031267] | 10567.9737178943 | -0.222197616171926 | 0.868298420107006 | 1 |
| O43815 | O43815 | STRN_HUMAN | Striatin | STRN | bicellular tight junction assembly [GO:0070830]; dendrite development [GO:0016358]; locomotory behavior [GO:0007626]; negative regulation of cell population proliferation [GO:0008285]; Wnt signaling pathway [GO:0016055] | bicellular tight junction [GO:0005923]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; FAR/SIN/STRIPAK complex [GO:0090443]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211] | armadillo repeat domain binding [GO:0070016]; calmodulin binding [GO:0005516]; nuclear estrogen receptor binding [GO:0030331]; protein phosphatase 2A binding [GO:0051721]; protein-containing complex binding [GO:0044877] | 9125.275262197345 | 0.0143758403255094 | 0.999999996589378 | 1 |
| Q13033 | Q13033 | STRN3_HUMAN | Striatin-3 (Cell cycle autoantigen SG2NA) (S/G2 antigen) | STRN3 | negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of intracellular estrogen receptor signaling pathway [GO:0033147]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to estradiol [GO:0032355] | cytoplasm [GO:0005737]; dendrite [GO:0030425]; FAR/SIN/STRIPAK complex [GO:0090443]; Golgi apparatus [GO:0005794]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991] | armadillo repeat domain binding [GO:0070016]; calmodulin binding [GO:0005516]; protein phosphatase 2A binding [GO:0051721]; protein-containing complex binding [GO:0044877]; small GTPase binding [GO:0031267] | 16710.10254774285 | 0.0200567932442524 | 0.999999999954163 | 1 |
| Q9NRL3 | Q9NRL3 | STRN4_HUMAN | Striatin-4 (Zinedin) | STRN4 | cytoplasm [GO:0005737]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; FAR/SIN/STRIPAK complex [GO:0090443]; membrane [GO:0016020] | armadillo repeat domain binding [GO:0070016]; calmodulin binding [GO:0005516]; protein phosphatase 2A binding [GO:0051721]; protein-containing complex binding [GO:0044877] | 6914.24184616817 | -0.0744616277365446 | 0.981339981510923 | 1 | |
| Q9UNE7 | Q9UNE7 | CHIP_HUMAN | E3 ubiquitin-protein ligase CHIP (EC 2.3.2.27) (Antigen NY-CO-7) (CLL-associated antigen KW-8) (Carboxy terminus of Hsp70-interacting protein) (RING-type E3 ubiquitin transferase CHIP) (STIP1 homology and U box-containing protein 1) | STUB1 | cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to misfolded protein [GO:0071218]; chaperone-mediated autophagy [GO:0061684]; DNA repair [GO:0006281]; endoplasmic reticulum unfolded protein response [GO:0030968]; ERAD pathway [GO:0036503]; ERBB2 signaling pathway [GO:0038128]; MAPK cascade [GO:0000165]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; positive regulation of chaperone-mediated protein complex assembly [GO:0090035]; positive regulation of ERAD pathway [GO:1904294]; positive regulation of mitophagy [GO:1901526]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of proteolysis [GO:0045862]; positive regulation of smooth muscle cell apoptotic process [GO:0034393]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein K63-linked ubiquitination [GO:0070534]; protein maturation [GO:0051604]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; protein stabilization [GO:0050821]; protein ubiquitination [GO:0016567]; regulation of glucocorticoid metabolic process [GO:0031943]; regulation of protein stability [GO:0031647]; response to ischemia [GO:0002931]; ubiquitin-dependent protein catabolic process [GO:0006511] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrion [GO:0005739]; nuclear inclusion body [GO:0042405]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein folding chaperone complex [GO:0101031]; ubiquitin conjugating enzyme complex [GO:0031371]; ubiquitin ligase complex [GO:0000151]; Z disc [GO:0030018] | enzyme binding [GO:0019899]; G protein-coupled receptor binding [GO:0001664]; heat shock protein binding [GO:0031072]; Hsp70 protein binding [GO:0030544]; Hsp90 protein binding [GO:0051879]; kinase binding [GO:0019900]; misfolded protein binding [GO:0051787]; protein homodimerization activity [GO:0042803]; protein-folding chaperone binding [GO:0051087]; protein-macromolecule adaptor activity [GO:0030674]; R-SMAD binding [GO:0070412]; SMAD binding [GO:0046332]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; ubiquitin-ubiquitin ligase activity [GO:0034450] | 22972.408197384 | 0.101860654331723 | 0.717618924857423 | 1 |
| O14662 | O14662 | STX16_HUMAN | Syntaxin-16 (Syn16) | STX16 | endocytic recycling [GO:0032456]; intracellular protein transport [GO:0006886]; retrograde transport, endosome to Golgi [GO:0042147]; vesicle docking [GO:0048278]; vesicle fusion [GO:0006906] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; endomembrane system [GO:0012505]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi cisterna [GO:0031985]; Golgi membrane [GO:0000139]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; SNARE complex [GO:0031201]; synaptic vesicle membrane [GO:0030672]; trans-Golgi network [GO:0005802]; trans-Golgi network membrane [GO:0032588] | SNAP receptor activity [GO:0005484]; SNARE binding [GO:0000149]; syntaxin binding [GO:0019905] | 13243.08952156575 | -0.00418449452741703 | 0.999991355906605 | 1 |
| Q9P2W9 | Q9P2W9 | STX18_HUMAN | Syntaxin-18 (Cell growth-inhibiting gene 9 protein) | STX18 | endoplasmic reticulum membrane organization [GO:0090158]; intracellular protein transport [GO:0006886]; positive regulation of ER to Golgi vesicle-mediated transport [GO:1902953]; positive regulation of organelle assembly [GO:1902117]; regulation of Golgi organization [GO:1903358]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890] | endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; Golgi membrane [GO:0000139]; SNARE complex [GO:0031201] | protein domain specific binding [GO:0019904]; SNAP receptor activity [GO:0005484] | 11633.45899448445 | 0.14775962119896 | 0.777822817842769 | 1 |
| P32856 | P32856 | STX2_HUMAN | Syntaxin-2 (Epimorphin) | STX2 | acrosome reaction [GO:0007340]; animal organ morphogenesis [GO:0009887]; cellular response to oxidative stress [GO:0034599]; cornified envelope assembly [GO:1903575]; ectoderm development [GO:0007398]; exocytosis [GO:0006887]; intracellular protein transport [GO:0006886]; signal transduction [GO:0007165]; synaptic vesicle fusion to presynaptic active zone membrane [GO:0031629]; vesicle docking [GO:0048278] | basolateral plasma membrane [GO:0016323]; endomembrane system [GO:0012505]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; plasma membrane [GO:0005886]; presynaptic active zone membrane [GO:0048787]; protein-containing complex [GO:0032991]; SNARE complex [GO:0031201]; synaptic vesicle [GO:0008021] | calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; SNAP receptor activity [GO:0005484]; SNARE binding [GO:0000149]; structural molecule activity [GO:0005198] | 12246.4524611854 | -0.143037337099065 | 0.931796418991308 | 1 |
| Q13190 | Q13190 | STX5_HUMAN | Syntaxin-5 | STX5 | early endosome to Golgi transport [GO:0034498]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi disassembly [GO:0090166]; intracellular protein transport [GO:0006886]; positive regulation of protein catabolic process [GO:0045732]; regulation of Golgi organization [GO:1903358]; retrograde transport, endosome to Golgi [GO:0042147]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; vesicle docking [GO:0048278]; vesicle fusion [GO:0006906]; vesicle fusion with Golgi apparatus [GO:0048280] | cytosol [GO:0005829]; endomembrane system [GO:0012505]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; SNARE complex [GO:0031201]; vesicle [GO:0031982] | cadherin binding [GO:0045296]; SNAP receptor activity [GO:0005484]; SNARE binding [GO:0000149] | 22529.766134439997 | 0.0811489325429828 | 0.998879918833882 | 1 |
| P61764 | P61764 | STXB1_HUMAN | Syntaxin-binding protein 1 (MUNC18-1) (N-Sec1) (Protein unc-18 homolog 1) (Unc18-1) (Protein unc-18 homolog A) (Unc-18A) (p67) | STXBP1 | axon target recognition [GO:0007412]; cellular response to type II interferon [GO:0071346]; developmental process involved in reproduction [GO:0003006]; intracellular protein transport [GO:0006886]; long-term synaptic depression [GO:0060292]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein-containing complex assembly [GO:0031333]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; neuromuscular synaptic transmission [GO:0007274]; neuron apoptotic process [GO:0051402]; neurotransmitter secretion [GO:0007269]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; positive regulation of glutamate secretion, neurotransmission [GO:1903296]; positive regulation of mast cell degranulation [GO:0043306]; positive regulation of vesicle docking [GO:0106022]; presynaptic dense core vesicle exocytosis [GO:0099525]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; regulation of acrosomal vesicle exocytosis [GO:2000367]; regulation of SNARE complex assembly [GO:0035542]; regulation of synaptic vesicle fusion to presynaptic active zone membrane [GO:0031630]; regulation of synaptic vesicle priming [GO:0010807]; response to estradiol [GO:0032355]; SNARE complex assembly [GO:0035493]; synaptic vesicle maturation [GO:0016188]; synaptic vesicle priming [GO:0016082]; vesicle docking involved in exocytosis [GO:0006904]; vesicle-mediated transport [GO:0016192] | axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extrinsic component of presynaptic membrane [GO:0098888]; glutamatergic synapse [GO:0098978]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; parallel fiber to Purkinje cell synapse [GO:0098688]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; postsynapse [GO:0098794]; presynaptic active zone cytoplasmic component [GO:0098831]; presynaptic active zone membrane [GO:0048787]; presynaptic cytosol [GO:0099523]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141] | identical protein binding [GO:0042802]; phospholipase binding [GO:0043274]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; RNA binding [GO:0003723]; SNARE binding [GO:0000149]; syntaxin binding [GO:0019905]; syntaxin-1 binding [GO:0017075] | 28024.598913702852 | 0.107039777449087 | 0.945440648227075 | 1 |
| Q9P2R7 | Q9P2R7 | SUCB1_HUMAN | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial (EC 6.2.1.5) (ATP-specific succinyl-CoA synthetase subunit beta) (A-SCS) (Succinyl-CoA synthetase beta-A chain) (SCS-betaA) | SUCLA2 | succinate metabolic process [GO:0006105]; succinyl-CoA catabolic process [GO:1901289]; succinyl-CoA metabolic process [GO:0006104]; succinyl-CoA pathway [GO:0006781]; tricarboxylic acid cycle [GO:0006099] | extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; succinate-CoA ligase complex [GO:0042709]; succinate-CoA ligase complex (ADP-forming) [GO:0009361] | ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; succinate-CoA ligase (ADP-forming) activity [GO:0004775] | 17447.3216583772 | 0.0264074808317138 | 0.987251564777497 | 1 |
| P53597 | P53597 | SUCA_HUMAN | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial (EC 6.2.1.4) (EC 6.2.1.5) (Succinyl-CoA synthetase subunit alpha) (SCS-alpha) | SUCLG1 | succinyl-CoA catabolic process [GO:1901289]; tricarboxylic acid cycle [GO:0006099] | cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; succinate-CoA ligase complex (ADP-forming) [GO:0009361]; succinate-CoA ligase complex (GDP-forming) [GO:0045244] | nucleotide binding [GO:0000166]; RNA binding [GO:0003723]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]; succinate-CoA ligase (GDP-forming) activity [GO:0004776] | 30361.33590418545 | 0.0778114775406739 | 0.919025115760006 | 1 |
| Q96I99 | Q96I99 | SUCB2_HUMAN | Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial (EC 6.2.1.4) (GTP-specific succinyl-CoA synthetase subunit beta) (G-SCS) (GTPSCS) (Succinyl-CoA synthetase beta-G chain) (SCS-betaG) | SUCLG2 | succinate metabolic process [GO:0006105]; succinyl-CoA catabolic process [GO:1901289]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099] | mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; succinate-CoA ligase complex [GO:0042709]; succinate-CoA ligase complex (GDP-forming) [GO:0045244] | ATP binding [GO:0005524]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; protein-containing complex binding [GO:0044877]; succinate-CoA ligase (GDP-forming) activity [GO:0004776] | 29461.730798608398 | -0.0178748642320678 | 0.999938229339252 | 1 |
| Q8IX01 | Q8IX01 | SUGP2_HUMAN | SURP and G-patch domain-containing protein 2 (Arginine/serine-rich-splicing factor 14) (Splicing factor, arginine/serine-rich 14) | SUGP2 | mRNA processing [GO:0006397]; RNA splicing [GO:0008380] | nuclear body [GO:0016604]; nucleoplasm [GO:0005654] | RNA binding [GO:0003723] | 4297.22670237334 | -0.19062265083253 | 0.852763692374406 | 1 |
| P63165 | P63165 | SUMO1_HUMAN | Small ubiquitin-related modifier 1 (SUMO-1) (GAP-modifying protein 1) (GMP1) (SMT3 homolog 3) (Sentrin) (Ubiquitin-homology domain protein PIC1) (Ubiquitin-like protein SMT3C) (Smt3C) (Ubiquitin-like protein UBL1) | SUMO1 | cellular response to cadmium ion [GO:0071276]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; negative regulation of action potential [GO:0045759]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of protein import into nucleus [GO:0042308]; negative regulation of transcription by transcription factor localization [GO:0010621]; PML body organization [GO:0030578]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein-containing complex assembly [GO:0031334]; protein localization to nuclear pore [GO:0090204]; protein stabilization [GO:0050821]; protein sumoylation [GO:0016925]; regulation of calcium ion transmembrane transport [GO:1903169]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of protein localization [GO:0032880]; roof of mouth development [GO:0060021] | cytosol [GO:0005829]; nuclear body [GO:0016604]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nuclear stress granule [GO:0097165]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; septin ring [GO:0005940]; XY body [GO:0001741] | enzyme binding [GO:0019899]; potassium channel regulator activity [GO:0015459]; protein tag activity [GO:0031386]; RNA binding [GO:0003723]; small protein activating enzyme binding [GO:0044388]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-specific protease binding [GO:1990381] | 36582.3078631876 | 0.173776009030873 | 0.855898114241282 | 1 |
| O94901 | O94901 | SUN1_HUMAN | SUN domain-containing protein 1 (Protein unc-84 homolog A) (Sad1/unc-84 protein-like 1) | SUN1 | centrosome localization [GO:0051642]; homologous chromosome pairing at meiosis [GO:0007129]; meiotic attachment of telomere to nuclear envelope [GO:0070197]; nuclear matrix anchoring at nuclear membrane [GO:0090292]; nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration [GO:0021817]; ossification [GO:0001503]; response to mechanical stimulus [GO:0009612]; spermatogenesis [GO:0007283] | chromosome, telomeric region [GO:0000781]; cytoplasm [GO:0005737]; intracellular membrane-bounded organelle [GO:0043231]; meiotic nuclear membrane microtubule tethering complex [GO:0034993]; nuclear envelope [GO:0005635]; nuclear inner membrane [GO:0005637]; nuclear membrane [GO:0031965] | cytoskeleton-nuclear membrane anchor activity [GO:0140444]; identical protein binding [GO:0042802]; lamin binding [GO:0005521]; protein-membrane adaptor activity [GO:0043495] | 7938.579818626515 | -0.114809362519492 | 0.893075475198644 | 1 |
| P63272 | P63272 | SPT4H_HUMAN | Transcription elongation factor SPT4 (hSPT4) (DRB sensitivity-inducing factor 14 kDa subunit) (DSIF p14) (DRB sensitivity-inducing factor small subunit) (DSIF small subunit) | SUPT4H1 | negative regulation of DNA-templated transcription, elongation [GO:0032785]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription elongation by RNA polymerase II [GO:0034244]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription elongation by RNA polymerase II [GO:0034243]; transcription elongation by RNA polymerase II [GO:0006368]; transcription elongation-coupled chromatin remodeling [GO:0140673] | DSIF complex [GO:0032044]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] | protein heterodimerization activity [GO:0046982]; RNA polymerase II complex binding [GO:0000993]; zinc ion binding [GO:0008270] | 23843.106808117052 | 0.0447196046845043 | 0.96191051693411 | 1 |
| O00267 | O00267 | SPT5H_HUMAN | Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor 160 kDa subunit) (DSIF p160) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (Tat-cotransactivator 1 protein) (Tat-CT1 protein) | SUPT5H | negative regulation of DNA-templated transcription, elongation [GO:0032785]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; positive regulation of macroautophagy [GO:0016239]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription elongation by RNA polymerase II [GO:0034243]; transcription elongation by RNA polymerase II [GO:0006368]; transcription elongation-coupled chromatin remodeling [GO:0140673] | DSIF complex [GO:0032044]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] | chromatin binding [GO:0003682]; enzyme binding [GO:0019899]; mRNA binding [GO:0003729]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723] | 6405.5873489830155 | -0.0773076047221727 | 0.836183531349117 | 1 |
| Q8IYB8 | Q8IYB8 | SUV3_HUMAN | ATP-dependent RNA helicase SUPV3L1, mitochondrial (EC 3.6.4.13) (Suppressor of var1 3-like protein 1) (SUV3-like protein 1) | SUPV3L1 | DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; mitochondrial mRNA catabolic process [GO:0000958]; mitochondrial mRNA surveillance [GO:0035946]; mitochondrial ncRNA surveillance [GO:0035945]; mitochondrial RNA 3'-end processing [GO:0000965]; mitochondrial RNA catabolic process [GO:0000957]; mitochondrial RNA surveillance [GO:2000827]; mitochondrion organization [GO:0007005]; negative regulation of apoptotic process [GO:0043066]; positive regulation of cell growth [GO:0030307]; positive regulation of mitochondrial RNA catabolic process [GO:0000962]; RNA catabolic process [GO:0006401] | mitochondrial degradosome [GO:0045025]; mitochondrial matrix [GO:0005759]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; nucleus [GO:0005634] | 3'-5' RNA helicase activity [GO:0034458]; ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; DNA binding [GO:0003677]; DNA helicase activity [GO:0003678]; double-stranded RNA binding [GO:0003725]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724] | 8907.661724964275 | -0.111837268273518 | 0.915496497374753 | 1 |
| Q15526 | Q15526 | SURF1_HUMAN | Surfeit locus protein 1 | SURF1 | aerobic respiration [GO:0009060]; Golgi organization [GO:0007030]; mitochondrial cytochrome c oxidase assembly [GO:0033617]; respiratory chain complex IV assembly [GO:0008535] | endoplasmic reticulum [GO:0005783]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; mitochondrial respirasome [GO:0005746]; mitochondrion [GO:0005739] | cytochrome-c oxidase activity [GO:0004129] | 13466.46512908785 | -0.0996650726438668 | 0.66839196717251 | 1 |
| O75683 | O75683 | SURF6_HUMAN | Surfeit locus protein 6 | SURF6 | ribosomal large subunit biogenesis [GO:0042273]; ribosomal small subunit biogenesis [GO:0042274] | chromosome [GO:0005694]; granular component [GO:0001652]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654] | DNA binding [GO:0003677]; molecular condensate scaffold activity [GO:0140693]; RNA binding [GO:0003723] | 11264.375975630599 | 0.218200380472765 | 0.849566042145316 | 1 |
| O95425 | O95425 | SVIL_HUMAN | Supervillin (Archvillin) (p205/p250) | SVIL | actin filament severing [GO:0051014]; actin polymerization or depolymerization [GO:0008154]; barbed-end actin filament capping [GO:0051016]; positive regulation of cytokinesis [GO:0032467]; skeletal muscle tissue development [GO:0007519] | actin cytoskeleton [GO:0015629]; cell projection [GO:0042995]; cleavage furrow [GO:0032154]; costamere [GO:0043034]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; microtubule minus-end [GO:0036449]; midbody [GO:0030496]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; podosome [GO:0002102] | actin filament binding [GO:0051015]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546] | 7220.954845226481 | 0.0688663759389233 | 0.99995891109135 | 1 |
| Q6ZW31 | Q6ZW31 | SYDE1_HUMAN | Rho GTPase-activating protein SYDE1 (Synapse defective protein 1 homolog 1) (Protein syd-1 homolog 1) | SYDE1 | actin cytoskeleton organization [GO:0030036]; activation of GTPase activity [GO:0090630]; cell migration [GO:0016477]; positive regulation of trophoblast cell migration [GO:1901165]; regulation of cytoskeleton organization [GO:0051493]; regulation of Ras protein signal transduction [GO:0046578]; signal transduction [GO:0007165] | synaptic membrane [GO:0097060] | GTPase activator activity [GO:0005096]; GTPase regulator activity [GO:0030695] | 1261.2800974116249 | 0.10164883718993 | 0.868994433815147 | 1 |
| Q92797 | Q92797 | SYMPK_HUMAN | Symplekin | SYMPK | cell adhesion [GO:0007155]; mRNA polyadenylation [GO:0006378]; negative regulation of protein binding [GO:0032091] | bicellular tight junction [GO:0005923]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; mRNA cleavage and polyadenylation specificity factor complex [GO:0005847]; nuclear body [GO:0016604]; nuclear stress granule [GO:0097165]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] | 3694.72455767624 | 0.442475416659027 | 0.986414347685893 | 1 | |
| O60506 | O60506 | HNRPQ_HUMAN | Heterogeneous nuclear ribonucleoprotein Q (hnRNP Q) (Glycine- and tyrosine-rich RNA-binding protein) (GRY-RBP) (NS1-associated protein 1) (Synaptotagmin-binding, cytoplasmic RNA-interacting protein) | SYNCRIP | cellular response to type II interferon [GO:0071346]; CRD-mediated mRNA stabilization [GO:0070934]; mRNA modification [GO:0016556]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900152]; negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; negative regulation of translation [GO:0017148]; osteoblast differentiation [GO:0001649]; positive regulation of cytoplasmic translation [GO:2000767]; positive regulation of DNA demethylation [GO:1901537]; RNA processing [GO:0006396]; RNA splicing [GO:0008380] | catalytic step 2 spliceosome [GO:0071013]; CRD-mediated mRNA stability complex [GO:0070937]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; GAIT complex [GO:0097452]; histone pre-mRNA 3'end processing complex [GO:0071204]; mCRD-mediated mRNA stability complex [GO:0106002]; membrane [GO:0016020]; mRNA editing complex [GO:0045293]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904] | mRNA 5'-UTR binding [GO:0048027]; RNA binding [GO:0003723] | 162605.727115521 | 0.0741230390520071 | 0.878012702880622 | 1 |
| O15056 | O15056 | SYNJ2_HUMAN | Synaptojanin-2 (EC 3.1.3.36) (Synaptic inositol 1,4,5-trisphosphate 5-phosphatase 2) | SYNJ2 | membrane organization [GO:0061024]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; synaptic vesicle endocytosis [GO:0048488] | cell projection [GO:0042995]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; membrane raft [GO:0045121]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynapse [GO:0098793] | phosphatidylinositol phosphate 4-phosphatase activity [GO:0034596]; phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity [GO:0052629]; phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity [GO:0043813]; phosphatidylinositol-3-phosphate phosphatase activity [GO:0004438]; phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity [GO:0004439]; RNA binding [GO:0003723]; SH3 domain binding [GO:0017124] | 3928.271721198215 | -0.46987625213288 | 0.669411674559273 | 1 |
| P57105 | P57105 | SYJ2B_HUMAN | Synaptojanin-2-binding protein (Mitochondrial outer membrane protein 25) | SYNJ2BP | cell-cell adhesion [GO:0098609]; chemical synaptic transmission [GO:0007268]; embryo development [GO:0009790]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; negative regulation of angiogenesis [GO:0016525]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of sprouting angiogenesis [GO:1903671]; protein targeting [GO:0006605]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of endocytosis [GO:0030100]; regulation of Notch signaling pathway [GO:0008593]; Rho protein signal transduction [GO:0007266] | basolateral plasma membrane [GO:0016323]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; postsynaptic density membrane [GO:0098839] | 9320.15695237308 | -0.208605620147144 | 0.795282763673163 | 1 | |
| Q15750 | Q15750 | TAB1_HUMAN | TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 (Mitogen-activated protein kinase kinase kinase 7-interacting protein 1) (TGF-beta-activated kinase 1-binding protein 1) (TAK1-binding protein 1) | TAB1 | aorta development [GO:0035904]; cardiac septum development [GO:0003279]; coronary vasculature development [GO:0060976]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; lung development [GO:0030324]; non-canonical NF-kappaB signal transduction [GO:0038061]; positive regulation of cGAS/STING signaling pathway [GO:0141111]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; transforming growth factor beta receptor signaling pathway [GO:0007179] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; nuclear speck [GO:0016607]; protein-containing complex [GO:0032991] | mitogen-activated protein kinase p38 binding [GO:0048273]; molecular adaptor activity [GO:0060090]; protein serine/threonine kinase activator activity [GO:0043539]; protein serine/threonine phosphatase activity [GO:0004722]; protein-containing complex binding [GO:0044877] | 10401.12561994305 | 0.0285184808656474 | 0.999402634192042 | 1 |
| Q15545 | Q15545 | TAF7_HUMAN | Transcription initiation factor TFIID subunit 7 (RNA polymerase II TBP-associated factor subunit F) (Transcription initiation factor TFIID 55 kDa subunit) (TAF(II)55) (TAFII-55) (TAFII55) | TAF7 | DNA-templated transcription initiation [GO:0006352]; intracellular estrogen receptor signaling pathway [GO:0030520]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of MHC class I biosynthetic process [GO:0045344]; negative regulation of MHC class II biosynthetic process [GO:0045347]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription initiation by RNA polymerase II [GO:0060261]; regulation of DNA repair [GO:0006282]; regulation of transcription by RNA polymerase II [GO:0006357]; RNA polymerase II preinitiation complex assembly [GO:0051123]; spermine transport [GO:0000296]; transcription by RNA polymerase II [GO:0006366]; transcription initiation at RNA polymerase II promoter [GO:0006367] | cytoplasm [GO:0005737]; male germ cell nucleus [GO:0001673]; MLL1 complex [GO:0071339]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor TFIID complex [GO:0005669]; transcription factor TFTC complex [GO:0033276]; transcription regulator complex [GO:0005667] | DNA-binding transcription factor binding [GO:0140297]; histone acetyltransferase binding [GO:0035035]; nuclear thyroid hormone receptor binding [GO:0046966]; nuclear vitamin D receptor binding [GO:0042809]; P-TEFb complex binding [GO:0106140]; protein heterodimerization activity [GO:0046982]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; TFIIH-class transcription factor complex binding [GO:0001097]; transcription cis-regulatory region binding [GO:0000976] | 12011.7594592601 | -0.134830531322296 | 0.663558311580266 | 1 |
| Q96BW9 | Q96BW9 | TAM41_HUMAN | Phosphatidate cytidylyltransferase, mitochondrial (EC 2.7.7.41) (CDP-diacylglycerol synthase) (CDP-DAG synthase) (Mitochondrial translocator assembly and maintenance protein 41 homolog) (TAM41) | TAMM41 | cardiolipin biosynthetic process [GO:0032049]; CDP-diacylglycerol biosynthetic process [GO:0016024] | extrinsic component of mitochondrial inner membrane [GO:0031314]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739] | phosphatidate cytidylyltransferase activity [GO:0004605] | 1994.746926011065 | 0.202075334519926 | 0.955792481657504 | 1 |
| Q7L7X3 | Q7L7X3 | TAOK1_HUMAN | Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Kinase from chicken homolog B) (hKFC-B) (MARK Kinase) (MARKK) (Prostate-derived sterile 20-like kinase 2) (PSK-2) (PSK2) (Prostate-derived STE20-like kinase 2) (Thousand and one amino acid protein kinase 1) (TAOK1) (hTAOK1) | TAOK1 | central nervous system neuron development [GO:0021954]; DNA damage response [GO:0006974]; DNA repair [GO:0006281]; execution phase of apoptosis [GO:0097194]; microtubule cytoskeleton organization [GO:0000226]; mitotic G2 DNA damage checkpoint signaling [GO:0007095]; negative regulation of microtubule depolymerization [GO:0007026]; neuron cellular homeostasis [GO:0070050]; phosphorylation [GO:0016310]; positive regulation of JNK cascade [GO:0046330]; positive regulation of protein acetylation [GO:1901985]; positive regulation of stress-activated MAPK cascade [GO:0032874]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cytoskeleton organization [GO:0051493]; regulation of microtubule cytoskeleton organization [GO:0070507] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microtubule cytoskeleton [GO:0015630]; perinuclear region of cytoplasm [GO:0048471] | alpha-tubulin binding [GO:0043014]; ATP binding [GO:0005524]; beta-tubulin binding [GO:0048487]; kinase activity [GO:0016301]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activator activity [GO:0043539]; protein serine/threonine kinase activity [GO:0004674]; tau protein binding [GO:0048156]; tau-protein kinase activity [GO:0050321]; transferase activity [GO:0016740] | 9938.16550153268 | 0.0220461591721541 | 0.999999999615798 | 1 |
| Q9UL54 | Q9UL54 | TAOK2_HUMAN | Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Kinase from chicken homolog C) (hKFC-C) (Prostate-derived sterile 20-like kinase 1) (PSK-1) (PSK1) (Prostate-derived STE20-like kinase 1) (Thousand and one amino acid protein kinase 2) | TAOK2 | actin cytoskeleton organization [GO:0030036]; activation of protein kinase activity [GO:0032147]; apoptotic process [GO:0006915]; axonogenesis [GO:0007409]; basal dendrite arborization [GO:0150020]; basal dendrite morphogenesis [GO:0150019]; cell migration [GO:0016477]; DNA damage response [GO:0006974]; focal adhesion assembly [GO:0048041]; mitotic G2 DNA damage checkpoint signaling [GO:0007095]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of stress-activated MAPK cascade [GO:0032874]; protein autophosphorylation [GO:0046777]; protein targeting to membrane [GO:0006612]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell growth [GO:0001558]; regulation of cell shape [GO:0008360]; stress-activated MAPK cascade [GO:0051403] | actin cytoskeleton [GO:0015629]; axon [GO:0030424]; axonal growth cone [GO:0044295]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; receptor complex [GO:0043235] | ATP binding [GO:0005524]; MAP kinase kinase kinase activity [GO:0004709]; mitogen-activated protein kinase kinase binding [GO:0031434]; neuropilin binding [GO:0038191]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activator activity [GO:0043539]; protein serine/threonine kinase activity [GO:0004674]; tau protein binding [GO:0048156]; tau-protein kinase activity [GO:0050321] | 2320.50406232739 | -0.0940584659504197 | 0.942714980431368 | 1 |
| Q9H2K8 | Q9H2K8 | TAOK3_HUMAN | Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Cutaneous T-cell lymphoma-associated antigen HD-CL-09) (CTCL-associated antigen HD-CL-09) (Dendritic cell-derived protein kinase) (JNK/SAPK-inhibitory kinase) (Jun kinase-inhibitory kinase) (Kinase from chicken homolog A) (hKFC-A) (Thousand and one amino acid protein 3) | TAOK3 | DNA damage response [GO:0006974]; DNA repair [GO:0006281]; MAPK cascade [GO:0000165]; mitotic G2 DNA damage checkpoint signaling [GO:0007095]; negative regulation of JNK cascade [GO:0046329]; neuron projection morphogenesis [GO:0048812]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of stress-activated MAPK cascade [GO:0032874]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of cytoskeleton organization [GO:0051493]; regulation of MAPK cascade [GO:0043408] | cytoplasm [GO:0005737]; plasma membrane [GO:0005886] | ATP binding [GO:0005524]; protein kinase inhibitor activity [GO:0004860]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; transferase activity [GO:0016740] | 12097.50056787965 | -0.0124648869797891 | 0.999970808070537 | 1 |
| Q03518 | Q03518 | TAP1_HUMAN | Antigen peptide transporter 1 (APT1) (EC 7.4.2.14) (ATP-binding cassette sub-family B member 2) (Peptide supply factor 1) (Peptide transporter PSF1) (PSF-1) (Peptide transporter TAP1) (Peptide transporter involved in antigen processing 1) (Really interesting new gene 4 protein) (RING4) | TAP1 | adaptive immune response [GO:0002250]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; cytosol to endoplasmic reticulum transport [GO:0046967]; defense response [GO:0006952]; oligopeptide export from mitochondrion [GO:0090374]; peptide transport [GO:0015833]; protein transport [GO:0015031]; transmembrane transport [GO:0055085] | centriolar satellite [GO:0034451]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; mitochondrial inner membrane [GO:0005743]; phagocytic vesicle membrane [GO:0030670]; TAP complex [GO:0042825] | ABC-type oligopeptide transporter activity [GO:0015421]; ABC-type peptide antigen transporter activity [GO:0015433]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; metal ion binding [GO:0046872]; MHC class I protein binding [GO:0042288]; MHC class Ib protein binding [GO:0023029]; peptide antigen binding [GO:0042605]; peptide transmembrane transporter activity [GO:1904680]; protein homodimerization activity [GO:0042803]; TAP1 binding [GO:0046978]; TAP2 binding [GO:0046979] | 7008.002299220245 | 0.150814911514586 | 0.720780229635403 | 1 |
| Q9UK61 | Q9UK61 | TASOR_HUMAN | Protein TASOR (CTCL tumor antigen se89-1) (Retinoblastoma-associated protein RAP140) (Transgene activation suppressor protein) | TASOR | anterior/posterior axis specification, embryo [GO:0008595]; mesodermal to mesenchymal transition involved in gastrulation [GO:0060809]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045869]; positive regulation of DNA methylation-dependent heterochromatin formation [GO:0090309]; protein localization to heterochromatin [GO:0097355] | heterochromatin [GO:0000792]; nucleoplasm [GO:0005654] | chromatin binding [GO:0003682]; RNA binding [GO:0003723] | 2443.325042133655 | 0.074901973944607 | 0.86752550183796 | 1 |
| Q9BXI6 | Q9BXI6 | TB10A_HUMAN | TBC1 domain family member 10A (EBP50-PDX interactor of 64 kDa) (EPI64 protein) (Rab27A-GAP-alpha) | TBC1D10A | activation of cysteine-type endopeptidase activity [GO:0097202]; positive regulation of proteolysis [GO:0045862]; retrograde transport, endosome to Golgi [GO:0042147] | cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; plasma membrane [GO:0005886] | cadherin binding [GO:0045296]; GTPase activator activity [GO:0005096]; guanyl-nucleotide exchange factor activity [GO:0005085]; PDZ domain binding [GO:0030165] | 9555.041213766764 | 0.0562464989999907 | 0.862320957611804 | 1 |
| Q9NVG8 | Q9NVG8 | TBC13_HUMAN | TBC1 domain family member 13 | TBC1D13 | intracellular protein transport [GO:0006886] | cytosol [GO:0005829]; membrane [GO:0016020] | GTPase activator activity [GO:0005096]; small GTPase binding [GO:0031267] | 14852.39876054615 | -0.0590689120463184 | 0.976119982913939 | 1 |
| Q8TC07 | Q8TC07 | TBC15_HUMAN | TBC1 domain family member 15 (GTPase-activating protein RAB7) (GAP for RAB7) (Rab7-GAP) | TBC1D15 | regulation of GTPase activity [GO:0043087] | cytoplasm [GO:0005737]; extracellular region [GO:0005576] | GTPase activator activity [GO:0005096] | 8844.90689576666 | -0.0671519358735381 | 0.998674834501368 | 1 |
| Q9HA65 | Q9HA65 | TBC17_HUMAN | TBC1 domain family member 17 | TBC1D17 | autophagy [GO:0006914]; protein transport [GO:0015031]; retrograde transport, endosome to Golgi [GO:0042147] | autophagosome [GO:0005776]; cytosol [GO:0005829]; recycling endosome [GO:0055037] | GTPase activator activity [GO:0005096] | 11192.20974527535 | -0.0198583764347774 | 0.999361638499399 | 1 |
| Q96BZ9 | Q96BZ9 | TBC20_HUMAN | TBC1 domain family member 20 | TBC1D20 | acrosome assembly [GO:0001675]; COPII-coated vesicle cargo loading [GO:0090110]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; lens fiber cell morphogenesis [GO:0070309]; lipid droplet organization [GO:0034389]; positive regulation by host of viral genome replication [GO:0044829]; positive regulation by virus of viral protein levels in host cell [GO:0046726]; positive regulation of ER to Golgi vesicle-mediated transport [GO:1902953]; positive regulation of GTPase activity [GO:0043547]; seminiferous tubule development [GO:0072520]; virion assembly [GO:0019068] | endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; Golgi membrane [GO:0000139]; nuclear membrane [GO:0031965] | GTPase activator activity [GO:0005096]; small GTPase binding [GO:0031267] | 17811.08212338675 | 0.111867114641143 | 0.876717767061303 | 1 |
| Q92609 | Q92609 | TBCD5_HUMAN | TBC1 domain family member 5 | TBC1D5 | autophagy [GO:0006914]; macroautophagy [GO:0016236]; positive regulation of receptor internalization [GO:0002092]; protein transport [GO:0015031]; response to starvation [GO:0042594]; retrograde transport, endosome to Golgi [GO:0042147] | autophagosome [GO:0005776]; cytosol [GO:0005829]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; retromer complex [GO:0030904] | AP-2 adaptor complex binding [GO:0035612]; GTPase activator activity [GO:0005096]; protein-containing complex binding [GO:0044877]; retromer complex binding [GO:1905394] | 8959.420639513235 | -0.0276735321876086 | 0.935784111607834 | 1 |
| Q0IIM8 | Q0IIM8 | TBC8B_HUMAN | TBC1 domain family member 8B | TBC1D8B | glomerular filtration [GO:0003094]; vesicle-mediated transport [GO:0016192] | cytosol [GO:0005829] | calcium ion binding [GO:0005509]; GTPase activator activity [GO:0005096] | 6927.00987339902 | -0.033551121143613 | 0.999866650908331 | 1 |
| Q66K14 | Q66K14 | TBC9B_HUMAN | TBC1 domain family member 9B | TBC1D9B | membrane [GO:0016020] | calcium ion binding [GO:0005509]; GTPase activator activity [GO:0005096] | 13218.954916841649 | -0.0219644967549814 | 0.999999689712919 | 1 | |
| Q99426 | Q99426 | TBCB_HUMAN | Tubulin-folding cofactor B (Cytoskeleton-associated protein 1) (Cytoskeleton-associated protein CKAPI) (Tubulin-specific chaperone B) | TBCB | cell differentiation [GO:0030154]; cytoplasmic microtubule organization [GO:0031122]; establishment of mitotic spindle orientation [GO:0000132]; nervous system development [GO:0007399]; post-chaperonin tubulin folding pathway [GO:0007023]; tubulin complex assembly [GO:0007021] | axon [GO:0030424]; cell cortex [GO:0005938]; cell tip [GO:0051286]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; kinetochore [GO:0000776]; microtubule associated complex [GO:0005875]; microtubule cytoskeleton [GO:0015630]; microtubule plus-end [GO:0035371]; nucleus [GO:0005634]; spindle pole [GO:0000922] | alpha-tubulin binding [GO:0043014]; microtubule plus-end binding [GO:0051010] | 29815.445026971953 | 0.0684540538659651 | 0.942385701480958 | 1 |
| Q15814 | Q15814 | TBCC_HUMAN | Tubulin-specific chaperone C (Tubulin-folding cofactor C) (CFC) | TBCC | post-chaperonin tubulin folding pathway [GO:0007023]; protein folding [GO:0006457]; tubulin complex assembly [GO:0007021] | cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; microtubule [GO:0005874]; photoreceptor connecting cilium [GO:0032391] | GTPase activity [GO:0003924]; protein-folding chaperone binding [GO:0051087]; tubulin binding [GO:0015631] | 16723.9349883052 | -0.0769494505389707 | 0.769721260949479 | 1 |
| Q15813 | Q15813 | TBCE_HUMAN | Tubulin-specific chaperone E (Tubulin-folding cofactor E) | TBCE | adult locomotory behavior [GO:0008344]; developmental growth [GO:0048589]; microtubule cytoskeleton organization [GO:0000226]; mitotic spindle organization [GO:0007052]; muscle atrophy [GO:0014889]; peripheral nervous system neuron axonogenesis [GO:0048936]; post-chaperonin tubulin folding pathway [GO:0007023]; post-embryonic development [GO:0009791]; protein folding [GO:0006457]; tubulin complex assembly [GO:0007021] | cytoplasm [GO:0005737]; microtubule [GO:0005874] | alpha-tubulin binding [GO:0043014]; protein-folding chaperone binding [GO:0051087] | 8769.175555864565 | -0.0161950846827633 | 0.999999845150758 | 1 |
| Q5QJ74 | Q5QJ74 | TBCEL_HUMAN | Tubulin-specific chaperone cofactor E-like protein (EL) (Leucine-rich repeat-containing protein 35) | TBCEL | microtubule cytoskeleton organization [GO:0000226]; post-chaperonin tubulin folding pathway [GO:0007023]; tubulin complex assembly [GO:0007021] | cytoplasm [GO:0005737]; cytoskeleton [GO:0005856] | alpha-tubulin binding [GO:0043014] | 10614.62438095425 | -0.0510220919986159 | 0.99923759735471 | 1 |
| Q9Y4P3 | Q9Y4P3 | TBL2_HUMAN | Transducin beta-like protein 2 (WS beta-transducin repeats protein) (WS-betaTRP) (Williams-Beuren syndrome chromosomal region 13 protein) | TBL2 | cellular response to glucose starvation [GO:0042149]; cellular response to hypoxia [GO:0071456]; endoplasmic reticulum unfolded protein response [GO:0030968] | endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789] | phosphoprotein binding [GO:0051219]; protein kinase binding [GO:0019901]; RNA binding [GO:0003723]; translation initiation factor binding [GO:0031369] | 29895.79549255655 | -0.0514392321279146 | 0.949820904813482 | 1 |
| Q96EI5 | Q96EI5 | TCAL4_HUMAN | Transcription elongation factor A protein-like 4 (TCEA-like protein 4) (Transcription elongation factor S-II protein-like 4) | TCEAL4 | nucleus [GO:0005634] | 5725.814243103465 | 0.262854104919723 | 0.77444361909845 | 1 | ||
| O14776 | O14776 | TCRG1_HUMAN | Transcription elongation regulator 1 (TATA box-binding protein-associated factor 2S) (Transcription factor CA150) | TCERG1 | mRNA processing [GO:0006397]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription elongation by RNA polymerase II [GO:0034244]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation by RNA polymerase II [GO:0032968]; RNA splicing [GO:0008380] | nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] | identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA polymerase binding [GO:0070063]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; transcription coactivator activity [GO:0003713]; transcription coregulator activity [GO:0003712]; transcription corepressor activity [GO:0003714]; transcription elongation factor activity [GO:0003711]; ubiquitin-like protein conjugating enzyme binding [GO:0044390] | 9026.09035766962 | -0.156695273148635 | 0.942935740185946 | 1 |
| Q9BQ70 | Q9BQ70 | TCF25_HUMAN | Ribosome quality control complex subunit TCF25 (Nuclear localized protein 1) (Transcription factor 25) (TCF-25) | TCF25 | heart development [GO:0007507]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of protein K48-linked ubiquitination [GO:0061945]; rescue of stalled ribosome [GO:0072344]; ribosome-associated ubiquitin-dependent protein catabolic process [GO:1990116] | cytosol [GO:0005829]; nucleus [GO:0005634]; RQC complex [GO:1990112] | DNA binding [GO:0003677]; transcription corepressor activity [GO:0003714] | 5498.525088266269 | -0.0796786538326356 | 0.99735595550529 | 1 |
| P17987 | P17987 | TCPA_HUMAN | T-complex protein 1 subunit alpha (TCP-1-alpha) (CCT-alpha) (Chaperonin containing T-complex polypeptide 1 subunit 1) | TCP1 | binding of sperm to zona pellucida [GO:0007339]; chaperone-mediated protein folding [GO:0061077]; positive regulation of establishment of protein localization to telomere [GO:1904851]; positive regulation of protein localization to Cajal body [GO:1904871]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomerase RNA localization to Cajal body [GO:1904874]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein folding [GO:0006457]; protein stabilization [GO:0050821]; scaRNA localization to Cajal body [GO:0090666]; tubulin complex assembly [GO:0007021] | acrosomal vesicle [GO:0001669]; cell body [GO:0044297]; centrosome [GO:0005813]; chaperonin-containing T-complex [GO:0005832]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; heterochromatin [GO:0000792]; microtubule [GO:0005874]; pericentriolar material [GO:0000242]; zona pellucida receptor complex [GO:0002199] | ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-dependent protein folding chaperone [GO:0140662]; protein folding chaperone [GO:0044183]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082] | 100012.82870233845 | 0.00826015795089815 | 0.999999999953292 | 1 |
| Q9H7E2 | Q9H7E2 | TDRD3_HUMAN | Tudor domain-containing protein 3 | TDRD3 | chromatin organization [GO:0006325]; DNA topological change [GO:0006265] | cytosol [GO:0005829]; DNA topoisomerase III-beta-TDRD3 complex [GO:0140225]; Golgi apparatus [GO:0005794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] | chromatin binding [GO:0003682]; methylated histone binding [GO:0035064]; RNA binding [GO:0003723]; transcription coactivator activity [GO:0003713] | 4975.065082702849 | -0.0954019395978107 | 0.847340807241427 | 1 |
| Q99973 | Q99973 | TEP1_HUMAN | Telomerase protein component 1 (Telomerase-associated protein 1) (Telomerase protein 1) (p240) (p80 telomerase homolog) | TEP1 | telomere maintenance via recombination [GO:0000722] | chromosome, telomeric region [GO:0000781]; cytoplasm [GO:0005737]; nuclear matrix [GO:0016363]; ribonucleoprotein complex [GO:1990904]; telomerase holoenzyme complex [GO:0005697] | ATP binding [GO:0005524]; enzyme binding [GO:0019899]; p53 binding [GO:0002039]; RNA binding [GO:0003723]; telomerase activity [GO:0003720]; telomerase RNA binding [GO:0070034] | 5695.44623499833 | -0.124624339841367 | 0.98051405015397 | 1 |
| Q9UGI8 | Q9UGI8 | TES_HUMAN | Testin (TESS) | TES | negative regulation of cell population proliferation [GO:0008285] | cell junction [GO:0030054]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991] | cadherin binding [GO:0045296]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270] | 31476.06604612905 | -0.0258785049618419 | 0.999993247011842 | 1 |
| Q9NXF1 | Q9NXF1 | TEX10_HUMAN | Testis-expressed protein 10 | TEX10 | rRNA processing [GO:0006364] | mitochondrion [GO:0005739]; MLL1 complex [GO:0071339]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] | 5226.4193836634295 | -0.0753248132265155 | 0.99492648316408 | 1 | |
| Q9Y6I9 | Q9Y6I9 | TX264_HUMAN | Testis-expressed protein 264 (Putative secreted protein Zsig11) | TEX264 | protein-DNA covalent cross-linking repair [GO:0106300]; reticulophagy [GO:0061709] | autophagosome membrane [GO:0000421]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; replication fork [GO:0005657] | signaling receptor activity [GO:0038023] | 49278.08466810985 | 0.0416279930990607 | 0.829870042583903 | 1 |
| Q12800 | Q12800 | TFCP2_HUMAN | Alpha-globin transcription factor CP2 (SAA3 enhancer factor) (Transcription factor LSF) | TFCP2 | mRNA transcription by RNA polymerase II [GO:0042789]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] | chromatin [GO:0000785]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991] | cis-regulatory region sequence-specific DNA binding [GO:0000987]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]; transcription factor binding [GO:0008134] | 9432.44970703148 | -0.169987523773677 | 0.927130037561962 | 1 |
| P37173 | P37173 | TGFR2_HUMAN | TGF-beta receptor type-2 (TGFR-2) (EC 2.7.11.30) (TGF-beta type II receptor) (Transforming growth factor-beta receptor type II) (TGF-beta receptor type II) (TbetaR-II) | TGFBR2 | activation of protein kinase activity [GO:0032147]; aorta morphogenesis [GO:0035909]; aortic valve morphogenesis [GO:0003180]; apoptotic process [GO:0006915]; artery morphogenesis [GO:0048844]; atrioventricular valve morphogenesis [GO:0003181]; blood vessel development [GO:0001568]; brain development [GO:0007420]; branching involved in blood vessel morphogenesis [GO:0001569]; bronchus morphogenesis [GO:0060434]; cardiac left ventricle morphogenesis [GO:0003214]; cellular response to growth factor stimulus [GO:0071363]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic hemopoiesis [GO:0035162]; endocardial cushion fusion [GO:0003274]; epithelial to mesenchymal transition [GO:0001837]; gastrulation [GO:0007369]; growth plate cartilage chondrocyte growth [GO:0003430]; heart development [GO:0007507]; heart looping [GO:0001947]; in utero embryonic development [GO:0001701]; inferior endocardial cushion morphogenesis [GO:1905317]; Langerhans cell differentiation [GO:0061520]; lens development in camera-type eye [GO:0002088]; lens fiber cell apoptotic process [GO:1990086]; lung lobe morphogenesis [GO:0060463]; mammary gland morphogenesis [GO:0060443]; membranous septum morphogenesis [GO:0003149]; miRNA transport [GO:1990428]; myeloid dendritic cell differentiation [GO:0043011]; Notch signaling pathway [GO:0007219]; outflow tract morphogenesis [GO:0003151]; outflow tract septum morphogenesis [GO:0003148]; phosphorylation [GO:0016310]; positive regulation of angiogenesis [GO:0045766]; positive regulation of B cell tolerance induction [GO:0002663]; positive regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000563]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation [GO:1905007]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of NK T cell differentiation [GO:0051138]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of T cell tolerance induction [GO:0002666]; positive regulation of tolerance induction to self antigen [GO:0002651]; regulation of cell population proliferation [GO:0042127]; regulation of gene expression [GO:0010468]; regulation of stem cell differentiation [GO:2000736]; regulation of stem cell proliferation [GO:0072091]; response to cholesterol [GO:0070723]; response to xenobiotic stimulus [GO:0009410]; roof of mouth development [GO:0060021]; secondary palate development [GO:0062009]; SMAD protein signal transduction [GO:0060395]; smoothened signaling pathway [GO:0007224]; trachea formation [GO:0060440]; transforming growth factor beta receptor signaling pathway [GO:0007179]; tricuspid valve morphogenesis [GO:0003186]; vasculogenesis [GO:0001570]; ventricular septum morphogenesis [GO:0060412] | caveola [GO:0005901]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; transforming growth factor beta ligand-receptor complex [GO:0070021] | activin binding [GO:0048185]; activin receptor activity [GO:0017002]; ATP binding [GO:0005524]; glycosaminoglycan binding [GO:0005539]; kinase activator activity [GO:0019209]; metal ion binding [GO:0046872]; molecular adaptor activity [GO:0060090]; SMAD binding [GO:0046332]; transforming growth factor beta binding [GO:0050431]; transforming growth factor beta receptor activity [GO:0005024]; transforming growth factor beta receptor activity, type II [GO:0005026]; transmembrane receptor protein serine/threonine kinase activity [GO:0004675]; type I transforming growth factor beta receptor binding [GO:0034713]; type III transforming growth factor beta receptor binding [GO:0034714] | 8265.059305738596 | -0.225763084653737 | 0.737293415113086 | 1 |
| Q08188 | Q08188 | TGM3_HUMAN | Protein-glutamine gamma-glutamyltransferase E (EC 2.3.2.13) (Transglutaminase E) (TG(E)) (TGE) (TGase E) (Transglutaminase-3) (TGase-3) [Cleaved into: Protein-glutamine gamma-glutamyltransferase E 50 kDa catalytic chain; Protein-glutamine gamma-glutamyltransferase E 27 kDa non-catalytic chain] | TGM3 | hair follicle morphogenesis [GO:0031069]; keratinization [GO:0031424]; keratinocyte differentiation [GO:0030216]; peptide cross-linking [GO:0018149]; protein modification process [GO:0036211] | cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; protein-containing complex [GO:0032991] | acyltransferase activity [GO:0016746]; calcium ion binding [GO:0005509]; catalytic activity [GO:0003824]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; structural molecule activity [GO:0005198] | 637.083654239364 | -1.51644139110539 | 0.666943484562739 | 1 |
| Q9NWX6 | Q9NWX6 | THG1_HUMAN | Probable tRNA(His) guanylyltransferase (EC 2.7.7.79) (Induced in high glucose-1) (IHG-1) (Interphase cytoplasmic foci protein 45) (tRNA-histidine guanylyltransferase) | THG1L | mitochondrial fusion [GO:0008053]; protein homotetramerization [GO:0051289]; response to oxidative stress [GO:0006979]; stress-induced mitochondrial fusion [GO:1990046]; tRNA modification [GO:0006400]; tRNA processing [GO:0008033] | cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; transferase complex [GO:1990234] | ATP binding [GO:0005524]; GTP binding [GO:0005525]; guanyl-nucleotide exchange factor activity [GO:0005085]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; nucleotidyltransferase activity [GO:0016779]; tRNA binding [GO:0000049]; tRNA guanylyltransferase activity [GO:0008193] | 2967.474364005365 | -0.0758385536852523 | 0.860452766889669 | 1 |
| Q96FV9 | Q96FV9 | THOC1_HUMAN | THO complex subunit 1 (Tho1) (Nuclear matrix protein p84) (p84N5) (hTREX84) | THOC1 | apoptotic process [GO:0006915]; mRNA export from nucleus [GO:0006406]; mRNA processing [GO:0006397]; regulation of DNA-templated transcription elongation [GO:0032784]; RNA splicing [GO:0008380]; signal transduction [GO:0007165] | cytoplasm [GO:0005737]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; THO complex [GO:0000347]; THO complex part of transcription export complex [GO:0000445]; transcription export complex [GO:0000346] | DNA binding [GO:0003677]; RNA binding [GO:0003723] | 6110.21252695337 | -0.0589510624357962 | 0.942944650216211 | 1 |
| Q8NI27 | Q8NI27 | THOC2_HUMAN | THO complex subunit 2 (Tho2) (hTREX120) | THOC2 | blastocyst development [GO:0001824]; cell morphogenesis [GO:0000902]; generation of neurons [GO:0048699]; mRNA export from nucleus [GO:0006406]; mRNA processing [GO:0006397]; negative regulation of neuron projection development [GO:0010977]; neuron development [GO:0048666]; poly(A)+ mRNA export from nucleus [GO:0016973]; regulation of gene expression [GO:0010468]; regulation of mRNA export from nucleus [GO:0010793]; RNA splicing [GO:0008380]; stem cell division [GO:0017145] | nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; THO complex [GO:0000347]; THO complex part of transcription export complex [GO:0000445]; transcription export complex [GO:0000346] | mRNA binding [GO:0003729] | 2680.60832222768 | 0.041461869177807 | 0.899196427577015 | 1 |
| Q86W42 | Q86W42 | THOC6_HUMAN | THO complex subunit 6 homolog (Functional spliceosome-associated protein 35) (fSAP35) (WD repeat-containing protein 58) | THOC6 | apoptotic process [GO:0006915]; central nervous system development [GO:0007417]; mRNA export from nucleus [GO:0006406]; mRNA processing [GO:0006397]; RNA splicing [GO:0008380] | nuclear body [GO:0016604]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; THO complex [GO:0000347]; THO complex part of transcription export complex [GO:0000445]; transcription export complex [GO:0000346] | RNA binding [GO:0003723] | 7244.318377289021 | -0.105045431944728 | 0.781238373802103 | 1 |
| P52888 | P52888 | THOP1_HUMAN | Thimet oligopeptidase (EC 3.4.24.15) (Endopeptidase 24.15) (MP78) | THOP1 | peptide metabolic process [GO:0006518]; protein polyubiquitination [GO:0000209]; proteolysis [GO:0006508] | cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758] | metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222] | 13711.05541985025 | -0.00708294206564967 | 0.999999966230954 | 1 |
| Q9Y2W1 | Q9Y2W1 | TR150_HUMAN | Thyroid hormone receptor-associated protein 3 (BCLAF1 and THRAP3 family member 2) (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150) | THRAP3 | circadian rhythm [GO:0007623]; mRNA processing [GO:0006397]; mRNA stabilization [GO:0048255]; nuclear-transcribed mRNA catabolic process [GO:0000956]; positive regulation of circadian rhythm [GO:0042753]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA splicing [GO:0008380] | extracellular exosome [GO:0070062]; mediator complex [GO:0016592]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] | ATP binding [GO:0005524]; DNA binding [GO:0003677]; nuclear receptor coactivator activity [GO:0030374]; nuclear thyroid hormone receptor binding [GO:0046966]; nuclear vitamin D receptor binding [GO:0042809]; phosphoprotein binding [GO:0051219]; RNA binding [GO:0003723]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; transcription coactivator activity [GO:0003713]; transcription coregulator activity [GO:0003712] | 39412.2878629179 | -0.0309410157122766 | 0.999953276576539 | 1 |
| Q9NXG2 | Q9NXG2 | THUM1_HUMAN | THUMP domain-containing protein 1 | THUMPD1 | tRNA modification [GO:0006400] | nucleoplasm [GO:0005654] | RNA binding [GO:0003723] | 12163.0782561797 | 0.0648091073911179 | 0.989354789120317 | 1 |
| Q9BV44 | Q9BV44 | THUM3_HUMAN | tRNA (guanine(6)-N2)-methyltransferase THUMP3 (EC 2.1.1.256) (THUMP domain-containing protein 3) | THUMPD3 | tRNA methylation [GO:0030488] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleolus [GO:0005730] | tRNA (guanine(6)-N2)-methyltransferase activity [GO:0160117]; tRNA (guanine(7)-N2)-methyltransferase activity [GO:0160118]; tRNA (guanine) methyltransferase activity [GO:0016423]; tRNA binding [GO:0000049] | 3959.8039259805 | -0.220435020873857 | 0.886584020635768 | 1 |
| P31483 | P31483 | TIA1_HUMAN | Cytotoxic granule associated RNA binding protein TIA1 (Nucleolysin TIA-1 isoform p40) (RNA-binding protein TIA-1) (T-cell-restricted intracellular antigen-1) (TIA-1) (p40-TIA-1) | TIA1 | apoptotic process [GO:0006915]; mRNA processing [GO:0006397]; negative regulation of cytokine production [GO:0001818]; negative regulation of translation [GO:0017148]; positive regulation of epithelial cell apoptotic process [GO:1904037]; protein localization to cytoplasmic stress granule [GO:1903608]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of mRNA splicing, via spliceosome [GO:0048024]; RNA splicing [GO:0008380]; stress granule assembly [GO:0034063] | cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; nuclear stress granule [GO:0097165]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904] | mRNA 3'-UTR AU-rich region binding [GO:0035925]; mRNA 3'-UTR binding [GO:0003730]; poly(A) binding [GO:0008143]; RNA binding [GO:0003723] | 6178.476213761175 | 0.0640330854093286 | 0.860468820398886 | 1 |
| Q01085 | Q01085 | TIAR_HUMAN | Nucleolysin TIAR (TIA-1-related protein) | TIAL1 | apoptotic process [GO:0006915]; defense response [GO:0006952]; germ cell development [GO:0007281]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of hippo signaling [GO:0035332]; positive regulation of miRNA-mediated gene silencing [GO:2000637]; positive regulation of stem cell proliferation [GO:2000648]; regulation of transcription by RNA polymerase II [GO:0006357]; stem cell division [GO:0017145]; stem cell proliferation [GO:0072089] | cytolytic granule [GO:0044194]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] | DNA binding [GO:0003677]; mRNA 3'-UTR AU-rich region binding [GO:0035925]; mRNA 3'-UTR binding [GO:0003730]; protein-RNA adaptor activity [GO:0140517]; RNA binding [GO:0003723] | 33701.687292278395 | 0.0457884439497778 | 0.950672282210277 | 1 |
| Q9NQ88 | Q9NQ88 | TIGAR_HUMAN | Fructose-2,6-bisphosphatase TIGAR (EC 3.1.3.46) (TP53-induced glycolysis and apoptosis regulator) (TP53-induced glycolysis regulatory phosphatase) | TIGAR | cardiac muscle cell apoptotic process [GO:0010659]; cellular response to cobalt ion [GO:0071279]; cellular response to hypoxia [GO:0071456]; DNA damage response [GO:0006974]; fructose 2,6-bisphosphate metabolic process [GO:0006003]; glucose catabolic process to lactate via pyruvate [GO:0019661]; glycolytic process [GO:0006096]; intestinal epithelial cell development [GO:0060576]; mitophagy [GO:0000423]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of glycolytic process [GO:0045820]; negative regulation of mitophagy [GO:1901525]; negative regulation of programmed cell death [GO:0043069]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of DNA repair [GO:0045739]; positive regulation of hexokinase activity [GO:1903301]; positive regulation of pentose-phosphate shunt [GO:1905857]; reactive oxygen species metabolic process [GO:0072593]; regulation of pentose-phosphate shunt [GO:0043456]; regulation of response to DNA damage checkpoint signaling [GO:1902153]; response to gamma radiation [GO:0010332]; response to ischemia [GO:0002931]; response to xenobiotic stimulus [GO:0009410] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; nucleus [GO:0005634] | fructose-2,6-bisphosphate 2-phosphatase activity [GO:0004331] | 39952.5175972757 | 0.0610477033626442 | 0.792978127960313 | 1 |
| Q9Y5L4 | Q9Y5L4 | TIM13_HUMAN | Mitochondrial import inner membrane translocase subunit Tim13 | TIMM13 | protein insertion into mitochondrial inner membrane [GO:0045039]; protein targeting to mitochondrion [GO:0006626]; sensory perception of sound [GO:0007605] | fibrillar center [GO:0001650]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrial intermembrane space protein transporter complex [GO:0042719]; mitochondrion [GO:0005739] | zinc ion binding [GO:0008270] | 45558.6932938593 | -0.0671158385521739 | 0.980407171133426 | 1 |
| O43615 | O43615 | TIM44_HUMAN | Mitochondrial import inner membrane translocase subunit TIM44 | TIMM44 | intracellular protein transport [GO:0006886]; protein import into mitochondrial matrix [GO:0030150]; protein targeting to mitochondrion [GO:0006626] | fibrillar center [GO:0001650]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; TIM23 mitochondrial import inner membrane translocase complex [GO:0005744] | ATP binding [GO:0005524]; protein-folding chaperone binding [GO:0051087] | 20671.62840093435 | 0.0244038570900239 | 0.999863337374037 | 1 |
| P35625 | P35625 | TIMP3_HUMAN | Metalloproteinase inhibitor 3 (Protein MIG-5) (Tissue inhibitor of metalloproteinases 3) (TIMP-3) | TIMP3 | cellular response to organic substance [GO:0071310]; negative regulation of membrane protein ectodomain proteolysis [GO:0051045]; negative regulation of metalloendopeptidase activity [GO:1904684]; response to cytokine [GO:0034097]; response to hormone [GO:0009725]; visual perception [GO:0007601] | basement membrane [GO:0005604]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; platelet dense granule lumen [GO:0031089] | metal ion binding [GO:0046872]; metalloendopeptidase inhibitor activity [GO:0008191]; protease binding [GO:0002020] | 232652.04312222148 | 0.041927491440106 | 0.803662173742092 | 1 |
| Q5JTD0 | Q5JTD0 | TJAP1_HUMAN | Tight junction-associated protein 1 (Protein incorporated later into tight junctions) (Tight junction protein 4) | TJAP1 | Golgi organization [GO:0007030] | bicellular tight junction [GO:0005923]; endosome [GO:0005768]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802] | 12045.20279845675 | 0.0817695692493511 | 0.715066879749085 | 1 | |
| Q07157 | Q07157 | ZO1_HUMAN | Tight junction protein ZO-1 (Tight junction protein 1) (Zona occludens protein 1) (Zonula occludens protein 1) | TJP1 | actin cytoskeleton organization [GO:0030036]; actomyosin structure organization [GO:0031032]; adherens junction maintenance [GO:0034334]; cell-cell adhesion [GO:0098609]; cell-cell junction assembly [GO:0007043]; cell-cell junction organization [GO:0045216]; establishment of endothelial intestinal barrier [GO:0090557]; maintenance of blood-brain barrier [GO:0035633]; negative regulation of apoptotic process [GO:0043066]; negative regulation of stress fiber assembly [GO:0051497]; positive regulation of blood-brain barrier permeability [GO:1905605]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell-cell adhesion mediated by cadherin [GO:2000049]; positive regulation of sprouting angiogenesis [GO:1903672]; protein localization to adherens junction [GO:0071896]; protein localization to bicellular tight junction [GO:1902396]; protein localization to cell-cell junction [GO:0150105]; regulation of bicellular tight junction assembly [GO:2000810]; regulation of cell junction assembly [GO:1901888]; regulation of cytoskeleton organization [GO:0051493] | adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell junction [GO:0030054]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; gap junction [GO:0005921]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; tight junction [GO:0070160] | cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; cell adhesion molecule binding [GO:0050839] | 26762.4344068037 | -0.0805680819032152 | 0.917349858745812 | 1 |
| O00142 | O00142 | KITM_HUMAN | Thymidine kinase 2, mitochondrial (EC 2.7.1.21) (2'-deoxyuridine kinase TK2) (EC 2.7.1.74) (Deoxycytidine kinase TK2) (EC 2.7.1.-) (Mt-TK) | TK2 | deoxycytidine metabolic process [GO:0046092]; DNA biosynthetic process [GO:0071897]; nucleobase-containing compound metabolic process [GO:0006139]; phosphorylation [GO:0016310]; pyrimidine nucleoside salvage [GO:0043097]; thymidine metabolic process [GO:0046104] | cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739] | ATP binding [GO:0005524]; deoxycytidine kinase activity [GO:0004137]; deoxynucleoside kinase activity [GO:0019136]; nucleoside kinase activity [GO:0019206]; thymidine kinase activity [GO:0004797] | 4546.93792888982 | -0.033482088874219 | 0.987955984907702 | 1 |
| P29401 | P29401 | TKT_HUMAN | Transketolase (TK) (EC 2.2.1.1) | TKT | glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]; regulation of growth [GO:0040008]; xylulose 5-phosphate biosynthetic process [GO:1901159] | cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; peroxisome [GO:0005777]; vesicle [GO:0031982] | calcium ion binding [GO:0005509]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; thiamine pyrophosphate binding [GO:0030976]; transketolase activity [GO:0004802] | 105911.474021826 | 0.0747952380595082 | 0.888148646452694 | 1 |
| Q04726 | Q04726 | TLE3_HUMAN | Transducin-like enhancer protein 3 (Enhancer of split groucho-like protein 3) (ESG3) | TLE3 | animal organ morphogenesis [GO:0009887]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cold-induced thermogenesis [GO:0120163]; signal transduction [GO:0007165]; Wnt signaling pathway [GO:0016055] | beta-catenin-TCF complex [GO:1990907]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription regulator complex [GO:0005667] | transcription corepressor activity [GO:0003714] | 27799.44171217645 | 0.255956544085535 | 0.769667240935556 | 1 |
| Q9Y4G6 | Q9Y4G6 | TLN2_HUMAN | Talin-2 | TLN2 | cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-cell junction assembly [GO:0007043] | actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; synapse [GO:0045202] | actin binding [GO:0003779]; actin filament binding [GO:0051015]; integrin binding [GO:0005178]; structural constituent of cytoskeleton [GO:0005200]; structural molecule activity [GO:0005198] | 3770.190212113675 | -0.210888579431278 | 0.951365764650634 | 1 |
| O15321 | O15321 | TM9S1_HUMAN | Transmembrane 9 superfamily member 1 (MP70 protein family member) (hMP70) | TM9SF1 | autophagy [GO:0006914]; protein localization to membrane [GO:0072657] | autophagosome membrane [GO:0000421]; cytoplasmic vesicle [GO:0031410]; lysosomal membrane [GO:0005765]; membrane [GO:0016020] | 26500.503780814848 | -0.0708054925952761 | 0.751385204737938 | 1 | |
| Q99805 | Q99805 | TM9S2_HUMAN | Transmembrane 9 superfamily member 2 (p76) | TM9SF2 | ceramide metabolic process [GO:0006672]; glycosphingolipid biosynthetic process [GO:0006688]; protein localization to membrane [GO:0072657]; regulation of heparan sulfate proteoglycan biosynthetic process [GO:0010908] | endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; microtubule organizing center [GO:0005815]; plasma membrane [GO:0005886] | 40328.196126140596 | 0.0144402682866002 | 0.999823259242636 | 1 | |
| Q9HD45 | Q9HD45 | TM9S3_HUMAN | Transmembrane 9 superfamily member 3 (EP70-P-iso) (SM-11044-binding protein) | TM9SF3 | protein localization to membrane [GO:0072657] | endosome [GO:0005768]; membrane [GO:0016020]; trans-Golgi network [GO:0005802] | 27992.0807248379 | -0.0652934567913221 | 0.971123162672978 | 1 | |
| Q92544 | Q92544 | TM9S4_HUMAN | Transmembrane 9 superfamily member 4 (Tumor cannibalism associated protein 1) | TM9SF4 | cell adhesion [GO:0007155]; phagocytosis [GO:0006909]; positive regulation of protein exit from endoplasmic reticulum [GO:0070863]; positive regulation of protein localization to cell surface [GO:2000010]; protein localization to membrane [GO:0072657]; regulation of intracellular pH [GO:0051453]; response to hypoxia [GO:0001666]; vacuolar proton-transporting V-type ATPase complex assembly [GO:0070072]; vacuolar transport [GO:0007034] | early endosome [GO:0005769]; Golgi apparatus [GO:0005794]; membrane [GO:0016020] | 31694.906350338948 | -0.0322665845920062 | 0.93900962505557 | 1 | |
| Q13445 | Q13445 | TMED1_HUMAN | Transmembrane emp24 domain-containing protein 1 (Interleukin-1 receptor-like 1 ligand) (Putative T1/ST2 receptor-binding protein) (p24 family protein gamma-1) (Tp24) (p24gamma1) | TMED1 | cell-cell signaling [GO:0007267]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; innate immune response [GO:0045087]; intracellular protein transport [GO:0006886]; signal transduction [GO:0007165] | COPII-coated ER to Golgi transport vesicle [GO:0030134]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886] | cargo receptor activity [GO:0038024]; signaling receptor binding [GO:0005102] | 53116.054891794105 | 0.0202436183385825 | 0.999097675599343 | 1 |
| P49755 | P49755 | TMEDA_HUMAN | Transmembrane emp24 domain-containing protein 10 (Protein TMED10) (21 kDa transmembrane-trafficking protein) (S31I125) (S31III125) (Tmp-21-I) (Transmembrane protein Tmp21) (p23) (p24 family protein delta-1) (p24delta1) (p24delta) | TMED10 | COPI coating of Golgi vesicle [GO:0048205]; COPI-coated vesicle budding [GO:0035964]; COPII vesicle coating [GO:0048208]; cytosol to ERGIC protein transport [GO:0106273]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; intracellular protein transport [GO:0006886]; positive regulation of interleukin-1 production [GO:0032732]; positive regulation of protein secretion [GO:0050714]; protein localization to ERGIC [GO:0106272]; regulated exocytosis [GO:0045055]; regulation of amyloid-beta formation [GO:1902003]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; vesicle cargo loading [GO:0035459]; vesicle targeting, to, from or within Golgi [GO:0048199] | cis-Golgi network [GO:0005801]; COPI-coated vesicle [GO:0030137]; COPII-coated ER to Golgi transport vesicle [GO:0030134]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; ER to Golgi transport vesicle membrane [GO:0012507]; gamma-secretase complex [GO:0070765]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; melanosome [GO:0042470]; membrane [GO:0016020]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; trans-Golgi network transport vesicle [GO:0030140]; transport vesicle [GO:0030133]; zymogen granule membrane [GO:0042589] | cargo receptor activity [GO:0038024]; protein transmembrane transporter activity [GO:0008320]; syntaxin binding [GO:0019905] | 528168.9320663561 | 0.0965658289553828 | 0.914911800813342 | 1 |
| Q15363 | Q15363 | TMED2_HUMAN | Transmembrane emp24 domain-containing protein 2 (Membrane protein p24A) (p24) (p24 family protein beta-1) (p24beta1) | TMED2 | allantois development [GO:1905069]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; chorion development [GO:0060717]; COPI coating of Golgi vesicle [GO:0048205]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum membrane organization [GO:0090158]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; heart looping [GO:0001947]; inflammatory response [GO:0006954]; intracellular protein transport [GO:0006886]; labyrinthine layer blood vessel development [GO:0060716]; maintenance of protein localization in organelle [GO:0072595]; maternal placenta development [GO:0001893]; multicellular organism growth [GO:0035264]; negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation [GO:1903912]; negative regulation of GTPase activity [GO:0034260]; negative regulation of protein localization to plasma membrane [GO:1903077]; negative regulation of smoothened signaling pathway [GO:0045879]; neural tube closure [GO:0001843]; PERK-mediated unfolded protein response [GO:0036499]; positive regulation of gene expression [GO:0010628]; post-anal tail morphogenesis [GO:0036342]; protein localization to plasma membrane [GO:0072659]; protein secretion [GO:0009306]; regulation of SREBP signaling pathway [GO:2000638]; somite rostral/caudal axis specification [GO:0032525]; vesicle cargo loading [GO:0035459] | COPI-coated vesicle [GO:0030137]; COPI-coated vesicle membrane [GO:0030663]; COPII-coated ER to Golgi transport vesicle [GO:0030134]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi membrane [GO:0000139]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; transport vesicle [GO:0030133]; zymogen granule membrane [GO:0042589] | cargo receptor activity [GO:0038024]; frizzled binding [GO:0005109]; smoothened binding [GO:0005119] | 157545.840355506 | 0.144705486910427 | 0.845389378028288 | 1 |
| Q9BVK6 | Q9BVK6 | TMED9_HUMAN | Transmembrane emp24 domain-containing protein 9 (GMP25) (Glycoprotein 25L2) (p24 family protein alpha-2) (p24alpha2) (p25) | TMED9 | COPI coating of Golgi vesicle [GO:0048205]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; intracellular protein transport [GO:0006886]; positive regulation of organelle organization [GO:0010638] | COPII-coated ER to Golgi transport vesicle [GO:0030134]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; synaptic vesicle [GO:0008021]; trans-Golgi network transport vesicle [GO:0030140]; transport vesicle [GO:0030133] | cargo receptor activity [GO:0038024]; syntaxin binding [GO:0019905] | 142790.047007032 | 0.0530223894402927 | 0.994879187033623 | 1 |
| Q8NE00 | Q8NE00 | TM104_HUMAN | Transmembrane protein 104 | TMEM104 | membrane [GO:0016020] | 18589.12407665325 | -0.141995610259342 | 0.683924481688657 | 1 | ||
| Q86VY9 | Q86VY9 | T200A_HUMAN | Transmembrane protein 200A | TMEM200A | membrane [GO:0016020] | 14183.883988160851 | -0.0717141880968376 | 0.850307659602633 | 1 |
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| Q15149 | |||||||||
| Q99715 | |||||||||
| P02452 | |||||||||
| P02751 | |||||||||
| P98160 | |||||||||
| P08123 | |||||||||
| P02461 | |||||||||
| P07996 | |||||||||
| Q8WWI1 | |||||||||
| P05997 | |||||||||
| P20908 | |||||||||
| Q8WUJ3 | |||||||||
| P21333 | |||||||||
| O75369 | |||||||||
| Q15063 | |||||||||
| P02786 | |||||||||
| Q12884 | |||||||||
| P12814 | |||||||||
| Q9UDY2 | |||||||||
| Q14195 | |||||||||
| Q02952 | |||||||||
| Q9NZM1 | |||||||||
| P35579 | |||||||||
| P35354 | |||||||||
| P47895 | |||||||||
| Q09666 | |||||||||
| P11717 | |||||||||
| Q14112 | |||||||||
| Q13620 | |||||||||
| P43490 | |||||||||
| Q3SY69 | |||||||||
| P17812 | |||||||||
| P21980 | |||||||||
| Q16647 | |||||||||
| P01024 | |||||||||
| Q5SW79 | |||||||||
| P06396 | |||||||||
| P12111 | |||||||||
| P35221 | |||||||||
| P12429 | |||||||||
| P78559 | |||||||||
| Q76M96 | |||||||||
| Q16881 | |||||||||
| P07093 | |||||||||
| P27487 | |||||||||
| P15144 | |||||||||
| Q9H5V8 | |||||||||
| P08729 | |||||||||
| Q04828 | |||||||||
| O94925 | |||||||||
| P08473 | |||||||||
| Q8IVL5 | |||||||||
| P35442 | |||||||||
| O60716 | |||||||||
| P08253 | |||||||||
| Q16822 | |||||||||
| Q9UJ72 | |||||||||
| Q9Y617 | |||||||||
| Q8WX93 | |||||||||
| Q32MZ4 | |||||||||
| Q6P179 | |||||||||
| P48681 | |||||||||
| O95340 | |||||||||
| P21580 | |||||||||
| Q00341 | |||||||||
| P49748 | |||||||||
| O43854 | |||||||||
| P07942 | |||||||||
| Q96KC8 | |||||||||
| Q96PD2 | |||||||||
| Q13418 | |||||||||
| Q7Z7G0 | |||||||||
| Q04446 | |||||||||
| P19022 | |||||||||
| O00469 | |||||||||
| Q8WUF5 | |||||||||
| Q14767 | |||||||||
| Q13308 | |||||||||
| P46940 | |||||||||
| Q9NZ08 | |||||||||
| O60488 | |||||||||
| P35222 | |||||||||
| Q9H4M9 | |||||||||
| Q9NZU5 | |||||||||
| Q15113 | |||||||||
| O94808 | |||||||||
| Q9UI42 | |||||||||
| Q15417 | |||||||||
| Q15582 | |||||||||
| P35908 | |||||||||
| P00750 | |||||||||
| Q9UHD8 | |||||||||
| P11047 | |||||||||
| Q8N6G6 | |||||||||
| Q05682 | |||||||||
| P17342 | |||||||||
| Q16363 | |||||||||
| Q9NR12 | |||||||||
| P05362 | |||||||||
| P00966 | |||||||||
| P05120 | |||||||||
| P15121 | |||||||||
| P04179 | |||||||||
| Q15785 | |||||||||
| O60271 | |||||||||
| Q9Y6N5 | |||||||||
| Q9P0V9 | |||||||||
| Q8IVF2 | |||||||||
| P01584 | |||||||||
| Q96AQ6 | |||||||||
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