Selected Cell
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stat_data__min_2_Peptides
Sheet1
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| Q9Y478 | Q9Y478 | AAKB1_HUMAN | 5'-AMP-activated protein kinase subunit beta-1 (AMPK subunit beta-1) (AMPKb) | PRKAB1 | cellular response to nutrient levels [GO:0031669]; fatty acid biosynthetic process [GO:0006633]; nail development [GO:0035878]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein phosphorylation [GO:0006468]; signal transduction [GO:0007165] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleotide-activated protein kinase complex [GO:0031588]; nucleus [GO:0005634] | protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901] | 12126.869861232699 | 0.0536482336129373 | 0.975159029422297 | 1 |
| O43741 | O43741 | AAKB2_HUMAN | 5'-AMP-activated protein kinase subunit beta-2 (AMPK subunit beta-2) | PRKAB2 | cellular response to nutrient levels [GO:0031669]; fatty acid biosynthetic process [GO:0006633]; positive regulation of cold-induced thermogenesis [GO:0120162]; signal transduction [GO:0007165] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleotide-activated protein kinase complex [GO:0031588]; nucleus [GO:0005634] | protein kinase binding [GO:0019901] | 11836.1078759331 | -0.00799696500020826 | 0.99976798990843 | 1 |
| P22694 | P22694 | KAPCB_HUMAN | cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11) | PRKACB | adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; high-density lipoprotein particle assembly [GO:0034380]; negative regulation of smoothened signaling pathway [GO:0045879]; negative regulation of TORC1 signaling [GO:1904262]; neural tube closure [GO:0001843]; protein kinase A signaling [GO:0010737]; protein phosphorylation [GO:0006468]; regulation of protein processing [GO:0070613]; renal water homeostasis [GO:0003091]; signal transduction [GO:0007165] | cAMP-dependent protein kinase complex [GO:0005952]; centrosome [GO:0005813]; ciliary base [GO:0097546]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886] | AMP-activated protein kinase activity [GO:0004679]; ATP binding [GO:0005524]; cAMP-dependent protein kinase activity [GO:0004691]; magnesium ion binding [GO:0000287]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; ubiquitin protein ligase binding [GO:0031625] | 20506.1412253756 | 0.0306151361768964 | 0.999760681312268 | 1 |
| Q05655 | Q05655 | KPCD_HUMAN | Protein kinase C delta type (EC 2.7.11.13) (Tyrosine-protein kinase PRKCD) (EC 2.7.10.2) (nPKC-delta) [Cleaved into: Protein kinase C delta type regulatory subunit; Protein kinase C delta type catalytic subunit (Sphingosine-dependent protein kinase-1) (SDK1)] | PRKCD | activation of protein kinase activity [GO:0032147]; apoptotic process [GO:0006915]; B cell proliferation [GO:0042100]; cell chemotaxis [GO:0060326]; cell cycle [GO:0007049]; cellular response to angiotensin [GO:1904385]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hydroperoxide [GO:0071447]; cellular response to UV [GO:0034644]; cellular senescence [GO:0090398]; defense response to bacterium [GO:0042742]; DNA damage response [GO:0006974]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immunoglobulin mediated immune response [GO:0016064]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631]; negative regulation of actin filament polymerization [GO:0030837]; negative regulation of filopodium assembly [GO:0051490]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of inflammatory response [GO:0050728]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of peptidyl-tyrosine phosphorylation [GO:0050732]; negative regulation of platelet aggregation [GO:0090331]; negative regulation of protein binding [GO:0032091]; neutrophil activation [GO:0042119]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of endodeoxyribonuclease activity [GO:0032079]; positive regulation of glucosylceramide catabolic process [GO:2000753]; positive regulation of phospholipid scramblase activity [GO:1900163]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of sphingomyelin catabolic process [GO:2000755]; positive regulation of superoxide anion generation [GO:0032930]; post-translational protein modification [GO:0043687]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of ceramide biosynthetic process [GO:2000303]; regulation of mRNA stability [GO:0043488]; regulation of signaling receptor activity [GO:0010469]; signal transduction [GO:0007165]; termination of signal transduction [GO:0023021] | azurophil granule lumen [GO:0035578]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endolysosome [GO:0036019]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; mitochondrion [GO:0005739]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886] | ATP binding [GO:0005524]; diacylglycerol-dependent serine/threonine kinase activity [GO:0004697]; diacylglycerol-dependent, calcium-independent serine/threonine kinase activity [GO:0004699]; enzyme activator activity [GO:0008047]; enzyme binding [GO:0019899]; insulin receptor substrate binding [GO:0043560]; metal ion binding [GO:0046872]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] | 3517.538826330295 | 0.0293512492924647 | 0.918747369962059 | 1 |
| P41743 | P41743 | KPCI_HUMAN | Protein kinase C iota type (EC 2.7.11.13) (Atypical protein kinase C-lambda/iota) (PRKC-lambda/iota) (aPKC-lambda/iota) (nPKC-iota) | PRKCI | actin filament organization [GO:0007015]; cell migration [GO:0016477]; cell-cell junction organization [GO:0045216]; cellular response to chemical stress [GO:0062197]; cellular response to insulin stimulus [GO:0032869]; cytoskeleton organization [GO:0007010]; establishment of apical/basal cell polarity [GO:0035089]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; eye photoreceptor cell development [GO:0042462]; Golgi vesicle budding [GO:0048194]; intracellular signal transduction [GO:0035556]; membrane organization [GO:0061024]; negative regulation of apoptotic process [GO:0043066]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of glucose import [GO:0046326]; positive regulation of neuron projection development [GO:0010976]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of protein localization to plasma membrane [GO:1903078]; protein phosphorylation [GO:0006468]; protein targeting to membrane [GO:0006612]; regulation of postsynaptic membrane neurotransmitter receptor levels [GO:0099072]; response to interleukin-1 [GO:0070555]; secretion [GO:0046903]; vesicle-mediated transport [GO:0016192] | apical plasma membrane [GO:0016324]; bicellular tight junction [GO:0005923]; brush border [GO:0005903]; cell leading edge [GO:0031252]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; Golgi membrane [GO:0000139]; intercellular bridge [GO:0045171]; microtubule cytoskeleton [GO:0015630]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PAR polarity complex [GO:0120157]; plasma membrane [GO:0005886]; Schaffer collateral - CA1 synapse [GO:0098685]; Schmidt-Lanterman incisure [GO:0043220]; tight junction [GO:0070160] | ATP binding [GO:0005524]; diacylglycerol-dependent serine/threonine kinase activity [GO:0004697]; metal ion binding [GO:0046872]; phospholipid binding [GO:0005543]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] | 13584.592988424 | -0.0330450874461178 | 0.987013200750898 | 1 |
| O14744 | O14744 | ANM5_HUMAN | Protein arginine N-methyltransferase 5 (PRMT5) (EC 2.1.1.320) (72 kDa ICln-binding protein) (Histone-arginine N-methyltransferase PRMT5) (Jak-binding protein 1) (Shk1 kinase-binding protein 1 homolog) (SKB1 homolog) (SKB1Hs) [Cleaved into: Protein arginine N-methyltransferase 5, N-terminally processed] | PRMT5 | chromatin remodeling [GO:0006338]; circadian regulation of gene expression [GO:0032922]; DNA-templated transcription termination [GO:0006353]; endothelial cell activation [GO:0042118]; Golgi ribbon formation [GO:0090161]; liver regeneration [GO:0097421]; negative regulation of cell differentiation [GO:0045596]; negative regulation of gene expression via chromosomal CpG dinucleotide methylation [GO:0044027]; peptidyl-arginine methylation [GO:0018216]; peptidyl-arginine N-methylation [GO:0035246]; positive regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:1904992]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; positive regulation of oligodendrocyte differentiation [GO:0048714]; regulation of DNA-templated transcription [GO:0006355]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of mitotic nuclear division [GO:0007088]; regulation of signal transduction by p53 class mediator [GO:1901796]; spliceosomal snRNP assembly [GO:0000387] | chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; histone methyltransferase complex [GO:0035097]; methylosome [GO:0034709]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] | E-box binding [GO:0070888]; histone arginine N-methyltransferase activity [GO:0008469]; histone H3 methyltransferase activity [GO:0140938]; histone H4R3 methyltransferase activity [GO:0044020]; histone methyltransferase activity [GO:0042054]; identical protein binding [GO:0042802]; methyl-CpG binding [GO:0008327]; methyltransferase activity [GO:0008168]; p53 binding [GO:0002039]; protein heterodimerization activity [GO:0046982]; protein-arginine N-methyltransferase activity [GO:0016274]; protein-arginine omega-N symmetric methyltransferase activity [GO:0035243]; ribonucleoprotein complex binding [GO:0043021]; transcription corepressor activity [GO:0003714] | 20038.338224893603 | -0.0509506206680109 | 0.967533497092588 | 1 |
| Q9UMS4 | Q9UMS4 | PRP19_HUMAN | Pre-mRNA-processing factor 19 (EC 2.3.2.27) (Nuclear matrix protein 200) (PRP19/PSO4 homolog) (hPso4) (RING-type E3 ubiquitin transferase PRP19) (Senescence evasion factor) | PRPF19 | DNA damage checkpoint signaling [GO:0000077]; double-strand break repair via nonhomologous end joining [GO:0006303]; lipid biosynthetic process [GO:0008610]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; proteasomal protein catabolic process [GO:0010498]; protein K63-linked ubiquitination [GO:0070534]; protein localization [GO:0008104]; protein polyubiquitination [GO:0000209]; spliceosomal complex assembly [GO:0000245]; spliceosomal tri-snRNP complex assembly [GO:0000244] | catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; lipid droplet [GO:0005811]; membrane [GO:0016020]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; Prp19 complex [GO:0000974]; site of double-strand break [GO:0035861]; spindle [GO:0005819]; spliceosomal complex [GO:0005681]; U2-type catalytic step 1 spliceosome [GO:0071006]; U2-type catalytic step 2 spliceosome [GO:0071007] | identical protein binding [GO:0042802]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; ubiquitin-ubiquitin ligase activity [GO:0034450] | 33487.97895309775 | -0.0654545472277232 | 0.942575572252526 | 1 |
| O43395 | O43395 | PRPF3_HUMAN | U4/U6 small nuclear ribonucleoprotein Prp3 (Pre-mRNA-splicing factor 3) (hPrp3) (U4/U6 snRNP 90 kDa protein) | PRPF3 | mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; RNA splicing [GO:0008380]; RNA splicing, via transesterification reactions [GO:0000375]; spliceosomal tri-snRNP complex assembly [GO:0000244] | Cajal body [GO:0015030]; cytosol [GO:0005829]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spliceosomal complex [GO:0005681]; U2-type precatalytic spliceosome [GO:0071005]; U4/U6 x U5 tri-snRNP complex [GO:0046540] | identical protein binding [GO:0042802]; RNA binding [GO:0003723] | 13887.406488187651 | 0.116682225124911 | 0.992630503416843 | 1 |
| O43172 | O43172 | PRP4_HUMAN | U4/U6 small nuclear ribonucleoprotein Prp4 (PRP4 homolog) (hPrp4) (U4/U6 snRNP 60 kDa protein) (WD splicing factor Prp4) | PRPF4 | mRNA splicing, via spliceosome [GO:0000398]; RNA processing [GO:0006396]; RNA splicing [GO:0008380]; RNA splicing, via transesterification reactions [GO:0000375] | Cajal body [GO:0015030]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spliceosomal complex [GO:0005681]; spliceosomal snRNP complex [GO:0097525]; U2-type precatalytic spliceosome [GO:0071005]; U4/U6 snRNP [GO:0071001]; U4/U6 x U5 tri-snRNP complex [GO:0046540] | U4 snRNA binding [GO:0030621]; U6 snRNA binding [GO:0017070] | 14727.896220432449 | 0.00431496510737475 | 0.999999870863179 | 1 |
| O75400 | O75400 | PR40A_HUMAN | Pre-mRNA-processing factor 40 homolog A (Fas ligand-associated factor 1) (Formin-binding protein 11) (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein 10) (HIP-10) (Huntingtin-interacting protein A) (Renal carcinoma antigen NY-REN-6) | PRPF40A | cell cycle [GO:0007049]; cell division [GO:0051301]; cell migration [GO:0016477]; cytoskeleton organization [GO:0007010]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA splicing, via spliceosome [GO:0000398]; regulation of cell shape [GO:0008360]; regulation of cytokinesis [GO:0032465] | membrane [GO:0016020]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; U1 snRNP [GO:0005685]; U2-type prespliceosome [GO:0071004] | RNA binding [GO:0003723] | 8964.25065773464 | -0.0647239778339737 | 0.979059656499119 | 1 |
| P11908 | P11908 | PRPS2_HUMAN | Ribose-phosphate pyrophosphokinase 2 (EC 2.7.6.1) (PPRibP) (Phosphoribosyl pyrophosphate synthase II) (PRS-II) | PRPS2 | 5-phosphoribose 1-diphosphate biosynthetic process [GO:0006015]; nucleobase-containing compound metabolic process [GO:0006139]; pentose-phosphate shunt [GO:0006098]; phosphorylation [GO:0016310]; purine nucleotide biosynthetic process [GO:0006164]; ribonucleoside monophosphate biosynthetic process [GO:0009156] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribose phosphate diphosphokinase complex [GO:0002189] | ATP binding [GO:0005524]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; ribose phosphate diphosphokinase activity [GO:0004749] | 9847.88084101045 | 0.0846826317328406 | 0.735993662201406 | 1 |
| O60256 | O60256 | KPRB_HUMAN | Phosphoribosyl pyrophosphate synthase-associated protein 2 (PRPP synthase-associated protein 2) (41 kDa phosphoribosypyrophosphate synthetase-associated protein) (PAP41) | PRPSAP2 | 5-phosphoribose 1-diphosphate biosynthetic process [GO:0006015]; bone development [GO:0060348]; nucleobase-containing compound metabolic process [GO:0006139]; purine nucleotide biosynthetic process [GO:0006164] | cytoplasm [GO:0005737]; ribose phosphate diphosphokinase complex [GO:0002189] | ATP binding [GO:0005524]; enzyme inhibitor activity [GO:0004857]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; ribose phosphate diphosphokinase activity [GO:0004749] | 17669.12702325875 | 0.0474207493292646 | 0.966188074713843 | 1 |
| Q96M27 | Q96M27 | PRRC1_HUMAN | Protein PRRC1 (Proline-rich and coiled-coil-containing protein 1) | PRRC1 | cytoplasm [GO:0005737]; Golgi apparatus [GO:0005794] | protein kinase A regulatory subunit binding [GO:0034237] | 46930.339526813696 | 0.107740855464307 | 0.841407205517633 | 1 | |
| P48634 | P48634 | PRC2A_HUMAN | Protein PRRC2A (HLA-B-associated transcript 2) (Large proline-rich protein BAT2) (Proline-rich and coiled-coil-containing protein 2A) (Protein G2) | PRRC2A | cell differentiation [GO:0030154] | cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] | RNA binding [GO:0003723] | 9492.63614086105 | 0.0632471108552161 | 0.997763602150975 | 1 |
| Q5JSZ5 | Q5JSZ5 | PRC2B_HUMAN | Protein PRRC2B (HLA-B-associated transcript 2-like 1) (Proline-rich coiled-coil protein 2B) | PRRC2B | cell differentiation [GO:0030154] | RNA binding [GO:0003723] | 3316.02269384054 | -0.0149497790801245 | 0.999359237431617 | 1 | |
| Q9Y520 | Q9Y520 | PRC2C_HUMAN | Protein PRRC2C (BAT2 domain-containing protein 1) (HBV X-transactivated gene 2 protein) (HBV XAg-transactivated protein 2) (HLA-B-associated transcript 2-like 2) (Proline-rich and coiled-coil-containing protein 2C) | PRRC2C | hematopoietic progenitor cell differentiation [GO:0002244]; stress granule assembly [GO:0034063] | cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; membrane [GO:0016020] | RNA binding [GO:0003723] | 13562.754337634698 | -0.0809375522631701 | 0.994969943898719 | 1 |
| P54821;Q99811 | P54821 | PRRX1_HUMAN | Paired mesoderm homeobox protein 1 (Homeobox protein PHOX1) (Paired-related homeobox protein 1) (PRX-1) | PRRX1 | artery morphogenesis [GO:0048844]; cartilage development [GO:0051216]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic limb morphogenesis [GO:0030326]; inner ear morphogenesis [GO:0042472]; mesenchymal cell proliferation [GO:0010463]; middle ear morphogenesis [GO:0042474]; neuron fate determination [GO:0048664]; neuronal stem cell population maintenance [GO:0097150]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of neuron projection regeneration [GO:0070570]; regulation of transcription by RNA polymerase II [GO:0006357]; roof of mouth development [GO:0060021]; smoothened signaling pathway [GO:0007224]; stem cell proliferation [GO:0072089] | chromatin [GO:0000785]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] | DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; HMG box domain binding [GO:0071837]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629] | 14322.551434499 | -0.15418258494338 | 0.92516566513491 | 1 |
| P07602 | P07602 | SAP_HUMAN | Prosaposin (Proactivator polypeptide) [Cleaved into: Saposin-A (Protein A); Saposin-B-Val; Saposin-B (Cerebroside sulfate activator) (CSAct) (Dispersin) (Sphingolipid activator protein 1) (SAP-1) (Sulfatide/GM1 activator); Saposin-C (A1 activator) (Co-beta-glucosidase) (Glucosylceramidase activator) (Sphingolipid activator protein 2) (SAP-2); Saposin-D (Component C) (Protein C)] | PSAP | adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; epithelial cell differentiation involved in prostate gland development [GO:0060742]; ganglioside GM1 transport to membrane [GO:1905572]; lysosomal transport [GO:0007041]; positive regulation of beta-galactosidase activity [GO:1903771]; prostate gland growth [GO:0060736]; regulation of autophagy [GO:0010506]; regulation of lipid metabolic process [GO:0019216]; sphingolipid metabolic process [GO:0006665] | azurophil granule membrane [GO:0035577]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; plasma membrane [GO:0005886] | enzyme activator activity [GO:0008047]; ganglioside GM1 binding [GO:1905573]; ganglioside GM2 binding [GO:1905574]; ganglioside GM3 binding [GO:1905575]; ganglioside GP1c binding [GO:1905577]; ganglioside GT1b binding [GO:1905576]; identical protein binding [GO:0042802]; phospholipid binding [GO:0005543]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; scaffold protein binding [GO:0097110] | 34293.045167547854 | 0.0359568883574269 | 0.997432664115654 | 1 |
| Q9NYI0 | Q9NYI0 | PSD3_HUMAN | PH and SEC7 domain-containing protein 3 (Epididymis tissue protein Li 20mP) (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6 D) (Exchange factor for ARF6 D) (Hepatocellular carcinoma-associated antigen 67) (Pleckstrin homology and SEC7 domain-containing protein 3) | PSD3 | regulation of ARF protein signal transduction [GO:0032012] | postsynaptic density [GO:0014069]; ruffle membrane [GO:0032587] | guanyl-nucleotide exchange factor activity [GO:0005085] | 6769.183484928764 | -0.150515670861986 | 0.88486764025942 | 1 |
| O75475 | O75475 | PSIP1_HUMAN | PC4 and SFRS1-interacting protein (CLL-associated antigen KW-7) (Dense fine speckles 70 kDa protein) (DFS 70) (Lens epithelium-derived growth factor) (Transcriptional coactivator p75/p52) | PSIP1 | chromatin remodeling [GO:0006338]; mRNA 5'-splice site recognition [GO:0000395]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979] | cytosol [GO:0005829]; euchromatin [GO:0000791]; heterochromatin [GO:0000792]; nuclear periphery [GO:0034399]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] | chromatin binding [GO:0003682]; DNA-binding transcription factor binding [GO:0140297]; RNA binding [GO:0003723]; supercoiled DNA binding [GO:0097100]; transcription coactivator activity [GO:0003713] | 10667.44532487865 | 0.246051436612148 | 0.744901939201016 | 1 |
| P49721 | P49721 | PSB2_HUMAN | Proteasome subunit beta type-2 (Macropain subunit C7-I) (Multicatalytic endopeptidase complex subunit C7-I) (Proteasome component C7-I) | PSMB2 | proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; response to organic cyclic compound [GO:0014070]; response to organonitrogen compound [GO:0010243] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774] | 139531.55924171052 | -0.0442387371545508 | 0.934687377717616 | 1 | |
| P28072 | P28072 | PSB6_HUMAN | Proteasome subunit beta type-6 (EC 3.4.25.1) (Macropain delta chain) (Multicatalytic endopeptidase complex delta chain) (Proteasome delta chain) (Proteasome subunit Y) | PSMB6 | proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774] | cadherin binding [GO:0045296]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298] | 79340.39463569771 | -0.0543202846719298 | 0.993331663767934 | 1 |
| Q99460 | Q99460 | PSMD1_HUMAN | 26S proteasome non-ATPase regulatory subunit 1 (26S proteasome regulatory subunit RPN2) (26S proteasome regulatory subunit S1) (26S proteasome subunit p112) | PSMD1 | proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of protein catabolic process [GO:0042176] | azurophil granule lumen [GO:0035578]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome accessory complex [GO:0022624]; proteasome complex [GO:0000502]; proteasome regulatory particle [GO:0005838]; proteasome regulatory particle, base subcomplex [GO:0008540]; proteasome storage granule [GO:0034515] | enzyme regulator activity [GO:0030234]; ubiquitin protein ligase binding [GO:0031625] | 34218.806192620104 | -0.0340546114271574 | 0.999999965211846 | 1 |
| O75832 | O75832 | PSD10_HUMAN | 26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin) (p28(GANK)) | PSMD10 | apoptotic process [GO:0006915]; cytoplasmic sequestering of NF-kappaB [GO:0007253]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of telomere capping [GO:1904355]; proteasome regulatory particle assembly [GO:0070682]; protein localization to chromosome, telomeric region [GO:0070198]; protein localization to plasma membrane [GO:0072659]; regulation of transcription by RNA polymerase II [GO:0006357] | cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; intermediate filament cytoskeleton [GO:0045111]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; proteasome complex [GO:0000502] | cytoskeletal protein binding [GO:0008092]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein-macromolecule adaptor activity [GO:0030674]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; transcription factor binding [GO:0008134]; transmembrane transporter binding [GO:0044325] | 19130.67476423225 | -0.0554923992312145 | 0.92705946522607 | 1 |
| Q15008 | Q15008 | PSMD6_HUMAN | 26S proteasome non-ATPase regulatory subunit 6 (26S proteasome regulatory subunit RPN7) (26S proteasome regulatory subunit S10) (Breast cancer-associated protein SGA-113M) (Phosphonoformate immuno-associated protein 4) (Proteasome regulatory particle subunit p44S10) (p42A) | PSMD6 | proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161] | cytosol [GO:0005829]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; proteasome accessory complex [GO:0022624]; proteasome complex [GO:0000502]; proteasome regulatory particle [GO:0005838]; secretory granule lumen [GO:0034774] | 55485.4003446583 | 0.0659769148065957 | 0.844325668824788 | 1 | |
| O95456 | O95456 | PSMG1_HUMAN | Proteasome assembly chaperone 1 (PAC-1) (Chromosome 21 leucine-rich protein) (C21-LRP) (Down syndrome critical region protein 2) | PSMG1 | cerebellar granule cell precursor proliferation [GO:0021930]; chaperone-mediated protein complex assembly [GO:0051131]; proteasome core complex assembly [GO:0080129] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein folding chaperone complex [GO:0101031] | molecular adaptor activity [GO:0060090]; proteasome binding [GO:0070628] | 22285.67484262925 | 0.197632878282677 | 0.837545026947711 | 1 |
| O95758 | O95758 | PTBP3_HUMAN | Polypyrimidine tract-binding protein 3 (Regulator of differentiation 1) (Rod1) | PTBP3 | anatomical structure morphogenesis [GO:0009653]; erythrocyte maturation [GO:0043249]; mRNA processing [GO:0006397]; negative regulation of RNA splicing [GO:0033119]; regulation of cell differentiation [GO:0045595]; regulation of RNA splicing [GO:0043484]; RNA splicing [GO:0008380] | nucleus [GO:0005634] | mRNA binding [GO:0003729]; RNA binding [GO:0003723] | 13608.7215393496 | 0.219398117062384 | 0.965249097427177 | 1 |
| Q96EY7 | Q96EY7 | PTCD3_HUMAN | Small ribosomal subunit protein mS39 (28S ribosomal protein S39, mitochondrial) (MRP-S39) (Pentatricopeptide repeat domain-containing protein 3, mitochondrial) (Transformation-related gene 15 protein) (TRG-15) | PTCD3 | mitochondrial translation [GO:0032543]; regulation of translation [GO:0006417] | cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial small ribosomal subunit [GO:0005763]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] | ribosomal small subunit binding [GO:0043024]; RNA binding [GO:0003723]; rRNA binding [GO:0019843] | 3766.5450538169453 | -0.0274241739631173 | 0.995003154174318 | 1 |
| P48651 | P48651 | PTSS1_HUMAN | Phosphatidylserine synthase 1 (PSS-1) (PtdSer synthase 1) (EC 2.7.8.29) (Serine-exchange enzyme I) | PTDSS1 | phosphatidylserine biosynthetic process [GO:0006659] | endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020] | L-serine-phosphatidylcholine phosphatidyltransferase activity [GO:0106258]; L-serine-phosphatidylethanolamine phosphatidyltransferase activity [GO:0106245]; transferase activity [GO:0016740] | 7747.991271359255 | 0.228932762674561 | 0.972006292670978 | 1 |
| Q9BVG9 | Q9BVG9 | PTSS2_HUMAN | Phosphatidylserine synthase 2 (PSS-2) (PtdSer synthase 2) (EC 2.7.8.29) (Serine-exchange enzyme II) | PTDSS2 | phosphatidylserine biosynthetic process [GO:0006659] | endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020] | CDP-diacylglycerol-serine O-phosphatidyltransferase activity [GO:0003882]; L-serine-phosphatidylethanolamine phosphatidyltransferase activity [GO:0106245]; transferase activity [GO:0016740] | 13566.3701293277 | 0.0203638491606119 | 0.950309481546126 | 1 |
| P60484 | P60484 | PTEN_HUMAN | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN (EC 3.1.3.16) (EC 3.1.3.48) (EC 3.1.3.67) (Inositol polyphosphate 3-phosphatase) (EC 3.1.3.-) (Mutated in multiple advanced cancers 1) (Phosphatase and tensin homolog) | PTEN | apoptotic process [GO:0006915]; brain morphogenesis [GO:0048854]; canonical Wnt signaling pathway [GO:0060070]; cell migration [GO:0016477]; cell motility [GO:0048870]; cellular response to electrical stimulus [GO:0071257]; central nervous system development [GO:0007417]; central nervous system myelin maintenance [GO:0032286]; central nervous system neuron axonogenesis [GO:0021955]; dendritic spine morphogenesis [GO:0060997]; dentate gyrus development [GO:0021542]; forebrain morphogenesis [GO:0048853]; heart development [GO:0007507]; learning or memory [GO:0007611]; localization [GO:0051179]; locomotor rhythm [GO:0045475]; locomotory behavior [GO:0007626]; multicellular organismal response to stress [GO:0033555]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell cycle G1/S phase transition [GO:1902807]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell size [GO:0045792]; negative regulation of cellular senescence [GO:2000773]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of dendritic spine morphogenesis [GO:0061002]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of keratinocyte migration [GO:0051548]; negative regulation of neuron projection development [GO:0010977]; negative regulation of organ growth [GO:0046621]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction [GO:0051898]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of synaptic vesicle clustering [GO:2000808]; negative regulation of vascular associated smooth muscle cell proliferation [GO:1904706]; negative regulation of wound healing, spreading of epidermal cells [GO:1903690]; neuron-neuron synaptic transmission [GO:0007270]; phosphatidylinositol 3-kinase/protein kinase B signal transduction [GO:0043491]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; postsynaptic density assembly [GO:0097107]; prepulse inhibition [GO:0060134]; presynaptic membrane assembly [GO:0097105]; protein dephosphorylation [GO:0006470]; protein stabilization [GO:0050821]; regulation of cellular component size [GO:0032535]; regulation of neuron projection development [GO:0010975]; regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction [GO:0051896]; regulation of protein stability [GO:0031647]; rhythmic synaptic transmission [GO:0060024]; social behavior [GO:0035176]; spindle assembly involved in female meiosis [GO:0007056]; synapse assembly [GO:0007416]; synapse maturation [GO:0060074] | apical plasma membrane [GO:0016324]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular region [GO:0005576]; myelin sheath adaxonal region [GO:0035749]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; postsynaptic density [GO:0014069]; Schmidt-Lanterman incisure [GO:0043220] | anaphase-promoting complex binding [GO:0010997]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase activity [GO:0030351]; inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity [GO:0051717]; lipid binding [GO:0008289]; molecular function inhibitor activity [GO:0140678]; myosin phosphatase activity [GO:0017018]; PDZ domain binding [GO:0030165]; phosphatidylinositol phosphate phosphatase activity [GO:0052866]; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity [GO:0016314]; phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity [GO:0051800]; phosphatidylinositol-3-phosphate phosphatase activity [GO:0004438]; phosphoprotein phosphatase activity [GO:0004721]; protein serine/threonine phosphatase activity [GO:0004722]; protein tyrosine phosphatase activity [GO:0004725]; ubiquitin-specific protease binding [GO:1990381] | 3205.28386324785 | -0.0762652763307154 | 0.99383146103021 | 1 |
| Q9H7Z7 | Q9H7Z7 | PGES2_HUMAN | Prostaglandin E synthase 2 (EC 5.3.99.3) (Membrane-associated prostaglandin E synthase-2) (mPGE synthase-2) (Microsomal prostaglandin E synthase 2) (mPGES-2) (Prostaglandin-H(2) E-isomerase) [Cleaved into: Prostaglandin E synthase 2 truncated form] | PTGES2 | cyclooxygenase pathway [GO:0019371]; lipid metabolic process [GO:0006629]; positive regulation of DNA-templated transcription [GO:0045893]; secretion [GO:0046903] | azurophil granule lumen [GO:0035578]; cytosol [GO:0005829]; extracellular region [GO:0005576]; Golgi membrane [GO:0000139]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471] | 12-hydroxyheptadecatrienoic acid synthase activity [GO:0036134]; DNA binding [GO:0003677]; glutathione binding [GO:0043295]; heme binding [GO:0020037]; lyase activity [GO:0016829]; prostaglandin-E synthase activity [GO:0050220] | 13460.3854780008 | 0.182163285152973 | 0.665560965532396 | 1 |
| Q9P2B2 | Q9P2B2 | FPRP_HUMAN | Prostaglandin F2 receptor negative regulator (CD9 partner 1) (CD9P-1) (Glu-Trp-Ile EWI motif-containing protein F) (EWI-F) (Prostaglandin F2-alpha receptor regulatory protein) (Prostaglandin F2-alpha receptor-associated protein) (CD antigen CD315) | PTGFRN | lipid droplet organization [GO:0034389]; myoblast fusion involved in skeletal muscle regeneration [GO:0014905] | cell surface [GO:0009986]; endoplasmic reticulum membrane [GO:0005789]; Golgi apparatus [GO:0005794] | 12334.492147234701 | 0.164475458703423 | 0.708208540882101 | 1 | |
| Q05397 | Q05397 | FAK1_HUMAN | Focal adhesion kinase 1 (FADK 1) (EC 2.7.10.2) (Focal adhesion kinase-related nonkinase) (FRNK) (Protein phosphatase 1 regulatory subunit 71) (PPP1R71) (Protein-tyrosine kinase 2) (p125FAK) (pp125FAK) | PTK2 | angiogenesis [GO:0001525]; axon guidance [GO:0007411]; cell migration [GO:0016477]; cell motility [GO:0048870]; detection of muscle stretch [GO:0035995]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; growth hormone receptor signaling pathway [GO:0060396]; heart morphogenesis [GO:0003007]; integrin-mediated signaling pathway [GO:0007229]; negative regulation of anoikis [GO:2000811]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-cell adhesion [GO:0022408]; netrin-activated signaling pathway [GO:0038007]; peptidyl-tyrosine phosphorylation [GO:0018108]; placenta development [GO:0001890]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of macrophage chemotaxis [GO:0010759]; positive regulation of macrophage proliferation [GO:0120041]; positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction [GO:0051897]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; positive regulation of wound healing [GO:0090303]; protein autophosphorylation [GO:0046777]; regulation of cell adhesion [GO:0030155]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of cytoskeleton organization [GO:0051493]; regulation of endothelial cell migration [GO:0010594]; regulation of epithelial cell migration [GO:0010632]; regulation of focal adhesion assembly [GO:0051893]; regulation of GTPase activity [GO:0043087]; regulation of osteoblast differentiation [GO:0045667]; regulation of protein phosphorylation [GO:0001932]; regulation of substrate adhesion-dependent cell spreading [GO:1900024]; signal complex assembly [GO:0007172]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vascular endothelial growth factor receptor signaling pathway [GO:0048010] | cell cortex [GO:0005938]; centrosome [GO:0005813]; ciliary basal body [GO:0036064]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; focal adhesion [GO:0005925]; intracellular membrane-bounded organelle [GO:0043231]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; stress fiber [GO:0001725] | actin binding [GO:0003779]; ATP binding [GO:0005524]; integrin binding [GO:0005178]; JUN kinase binding [GO:0008432]; molecular function activator activity [GO:0140677]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; protein tyrosine phosphatase activity [GO:0004725]; SH2 domain binding [GO:0042169] | 17941.6433501476 | -0.0204238965156119 | 0.999375201188745 | 1 |
| Q15257 | Q15257 | PTPA_HUMAN | Serine/threonine-protein phosphatase 2A activator (EC 5.2.1.8) (PP2A, subunit B', PR53 isoform) (Phosphotyrosyl phosphatase activator) (PTPA) (Serine/threonine-protein phosphatase 2A regulatory subunit 4) (Serine/threonine-protein phosphatase 2A regulatory subunit B') | PTPA | mitotic spindle organization [GO:0007052]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; negative regulation of protein dephosphorylation [GO:0035308]; positive regulation of apoptotic process [GO:0043065]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein dephosphorylation [GO:0035307]; regulation of phosphoprotein phosphatase activity [GO:0043666] | ATPase complex [GO:1904949]; calcium channel complex [GO:0034704]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein phosphatase type 2A complex [GO:0000159] | ATP binding [GO:0005524]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; protein homodimerization activity [GO:0042803]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase regulator activity [GO:0019888]; protein tyrosine phosphatase activator activity [GO:0008160]; signaling receptor binding [GO:0005102] | 59134.625398158256 | 0.0533399087872544 | 0.99704795605526 | 1 |
| P18031 | P18031 | PTN1_HUMAN | Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B) | PTPN1 | actin cytoskeleton organization [GO:0030036]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor recycling [GO:0038020]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338] | cytoplasm [GO:0005737]; cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; endosome lumen [GO:0031904]; mitochondrial crista [GO:0030061]; mitochondrial matrix [GO:0005759]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443] | cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; non-membrane spanning protein tyrosine phosphatase activity [GO:0004726]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270] | 42705.883710963506 | -0.00912607066887661 | 0.999999123264134 | 1 |
| Q06124 | Q06124 | PTN11_HUMAN | Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1D) (PTP-1D) (Protein-tyrosine phosphatase 2C) (PTP-2C) (SH-PTP2) (SHP-2) (Shp2) (SH-PTP3) | PTPN11 | atrioventricular canal development [GO:0036302]; axonogenesis [GO:0007409]; Bergmann glial cell differentiation [GO:0060020]; brain development [GO:0007420]; cellular response to epidermal growth factor stimulus [GO:0071364]; cerebellar cortex formation [GO:0021697]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage checkpoint signaling [GO:0000077]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB signaling pathway [GO:0038127]; face morphogenesis [GO:0060325]; fibroblast growth factor receptor signaling pathway [GO:0008543]; genitalia development [GO:0048806]; glucose homeostasis [GO:0042593]; heart development [GO:0007507]; homeostasis of number of cells within a tissue [GO:0048873]; hormone metabolic process [GO:0042445]; hormone-mediated signaling pathway [GO:0009755]; inner ear development [GO:0048839]; integrin-mediated signaling pathway [GO:0007229]; intestinal epithelial cell migration [GO:0061582]; megakaryocyte development [GO:0035855]; microvillus organization [GO:0032528]; multicellular organism growth [GO:0035264]; multicellular organismal reproductive process [GO:0048609]; negative regulation of cell adhesion mediated by integrin [GO:0033629]; negative regulation of chondrocyte differentiation [GO:0032331]; negative regulation of cortisol secretion [GO:0051463]; negative regulation of growth hormone secretion [GO:0060125]; negative regulation of insulin secretion [GO:0046676]; negative regulation of type I interferon production [GO:0032480]; neurotrophin TRK receptor signaling pathway [GO:0048011]; organ growth [GO:0035265]; peptidyl-tyrosine dephosphorylation [GO:0035335]; platelet formation [GO:0030220]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of glucose import [GO:0046326]; positive regulation of hormone secretion [GO:0046887]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of ossification [GO:0045778]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of tumor necrosis factor production [GO:0032760]; protein dephosphorylation [GO:0006470]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of protein export from nucleus [GO:0046825]; regulation of protein-containing complex assembly [GO:0043254]; regulation of type I interferon-mediated signaling pathway [GO:0060338]; T cell costimulation [GO:0031295]; triglyceride metabolic process [GO:0006641] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991] | cadherin binding [GO:0045296]; cell adhesion molecule binding [GO:0050839]; insulin receptor binding [GO:0005158]; molecular adaptor activity [GO:0060090]; non-membrane spanning protein tyrosine phosphatase activity [GO:0004726]; peptide hormone receptor binding [GO:0051428]; phosphoprotein phosphatase activity [GO:0004721]; phosphotyrosine residue binding [GO:0001784]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; signaling receptor complex adaptor activity [GO:0030159] | 27250.08027210265 | -0.0732022683786793 | 0.995041984053598 | 1 |
| P43378 | P43378 | PTN9_HUMAN | Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase MEG2) | PTPN9 | negative regulation of neuron projection development [GO:0010977]; peptidyl-tyrosine dephosphorylation [GO:0035335]; positive regulation of protein localization to plasma membrane [GO:1903078]; protein dephosphorylation [GO:0006470] | cytoplasm [GO:0005737]; neuron projection terminus [GO:0044306]; nucleoplasm [GO:0005654] | non-membrane spanning protein tyrosine phosphatase activity [GO:0004726]; protein tyrosine phosphatase activity [GO:0004725] | 6856.39661335071 | 0.140127207987835 | 0.800606946743969 | 1 |
| P18433 | P18433 | PTPRA_HUMAN | Receptor-type tyrosine-protein phosphatase alpha (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (EC 3.1.3.48) | PTPRA | dephosphorylation [GO:0016311]; insulin receptor signaling pathway [GO:0008286]; integrin-mediated signaling pathway [GO:0007229]; modulation of chemical synaptic transmission [GO:0050804]; regulation of focal adhesion assembly [GO:0051893] | extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; membrane [GO:0016020]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; Schaffer collateral - CA1 synapse [GO:0098685]; synaptic membrane [GO:0097060] | protein tyrosine phosphatase activity [GO:0004725]; transmembrane receptor protein tyrosine phosphatase activity [GO:0005001] | 6964.947419894135 | 0.0436847209638563 | 0.996140612154141 | 1 |
| P10586 | P10586 | PTPRF_HUMAN | Receptor-type tyrosine-protein phosphatase F (EC 3.1.3.48) (Leukocyte common antigen related) (LAR) | PTPRF | cell adhesion [GO:0007155]; cell migration [GO:0016477]; negative regulation of receptor binding [GO:1900121]; neuron projection regeneration [GO:0031102]; peptidyl-tyrosine dephosphorylation [GO:0035335]; regulation of axon regeneration [GO:0048679]; synaptic membrane adhesion [GO:0099560]; transmembrane receptor protein tyrosine phosphatase signaling pathway [GO:0007185] | extracellular exosome [GO:0070062]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; receptor complex [GO:0043235] | cell adhesion molecule binding [GO:0050839]; chondroitin sulfate proteoglycan binding [GO:0035373]; heparin binding [GO:0008201]; protein tyrosine phosphatase activity [GO:0004725]; protein-containing complex binding [GO:0044877]; transmembrane receptor protein tyrosine phosphatase activity [GO:0005001] | 9470.381600769571 | 0.0493351046111503 | 0.999989426173042 | 1 |
| Q15262 | Q15262 | PTPRK_HUMAN | Receptor-type tyrosine-protein phosphatase kappa (Protein-tyrosine phosphatase kappa) (R-PTP-kappa) (EC 3.1.3.48) | PTPRK | cell adhesion [GO:0007155]; cell migration [GO:0016477]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; focal adhesion assembly [GO:0048041]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of keratinocyte proliferation [GO:0010839]; protein dephosphorylation [GO:0006470]; protein localization to cell surface [GO:0034394]; signal transduction [GO:0007165]; transforming growth factor beta receptor signaling pathway [GO:0007179] | adherens junction [GO:0005912]; cell junction [GO:0030054]; cell surface [GO:0009986]; cell-cell junction [GO:0005911]; intracellular membrane-bounded organelle [GO:0043231]; leading edge membrane [GO:0031256]; membrane [GO:0016020]; plasma membrane [GO:0005886] | beta-catenin binding [GO:0008013]; gamma-catenin binding [GO:0045295]; protein kinase binding [GO:0019901]; protein tyrosine phosphatase activity [GO:0004725]; transmembrane receptor protein tyrosine phosphatase activity [GO:0005001] | 3335.593348076365 | -0.195793666825113 | 0.916073473594934 | 1 |
| Q13332 | Q13332 | PTPRS_HUMAN | Receptor-type tyrosine-protein phosphatase S (R-PTP-S) (EC 3.1.3.48) (Receptor-type tyrosine-protein phosphatase sigma) (R-PTP-sigma) | PTPRS | cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; corpus callosum development [GO:0022038]; establishment of endothelial intestinal barrier [GO:0090557]; hippocampus development [GO:0021766]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of axon extension [GO:0030517]; negative regulation of axon regeneration [GO:0048681]; negative regulation of collateral sprouting [GO:0048671]; negative regulation of dendritic spine development [GO:0061000]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of neuron projection development [GO:0010977]; negative regulation of toll-like receptor 9 signaling pathway [GO:0034164]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; regulation of postsynaptic density assembly [GO:0099151]; spinal cord development [GO:0021510]; synaptic membrane adhesion [GO:0099560]; trans-synaptic signaling [GO:0099537] | axon [GO:0030424]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; presynaptic membrane [GO:0042734]; receptor complex [GO:0043235]; Schaffer collateral - CA1 synapse [GO:0098685]; synaptic vesicle membrane [GO:0030672] | chondroitin sulfate binding [GO:0035374]; heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; phosphoprotein phosphatase activity [GO:0004721]; protein tyrosine phosphatase activity [GO:0004725] | 1229.048100713085 | -1.38860348417005 | 0.693548354916015 | 1 |
| Q03393 | Q03393 | PTPS_HUMAN | 6-pyruvoyl tetrahydrobiopterin synthase (PTP synthase) (PTPS) (EC 4.2.3.12) | PTS | amino acid metabolic process [GO:0006520]; central nervous system development [GO:0007417]; tetrahydrobiopterin biosynthetic process [GO:0006729] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739] | 6-carboxy-5,6,7,8-tetrahydropterin synthase activity [GO:0070497]; 6-pyruvoyltetrahydropterin synthase activity [GO:0003874]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872] | 10756.3270912384 | -0.0472534152264764 | 0.962519834455069 | 1 |
| Q9UHX1 | Q9UHX1 | PUF60_HUMAN | Poly(U)-binding-splicing factor PUF60 (60 kDa poly(U)-binding-splicing factor) (FUSE-binding protein-interacting repressor) (FBP-interacting repressor) (Ro-binding protein 1) (RoBP1) (Siah-binding protein 1) (Siah-BP1) | PUF60 | alternative mRNA splicing, via spliceosome [GO:0000380]; apoptotic process [GO:0006915]; mRNA splice site recognition [GO:0006376]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381] | catalytic step 2 spliceosome [GO:0071013]; cell junction [GO:0030054]; nucleoplasm [GO:0005654]; precatalytic spliceosome [GO:0071011] | cadherin binding [GO:0045296]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; RNA binding [GO:0003723] | 26907.8552839436 | 0.0530843684227718 | 0.954894153572835 | 1 |
| Q8TB72 | Q8TB72 | PUM2_HUMAN | Pumilio homolog 2 (Pumilio-2) | PUM2 | 3'-UTR-mediated mRNA destabilization [GO:0061158]; adipose tissue development [GO:0060612]; chromosome organization [GO:0051276]; hair follicle development [GO:0001942]; miRNA processing [GO:0035196]; mitochondrion organization [GO:0007005]; positive regulation of miRNA-mediated gene silencing [GO:2000637]; positive regulation of RIG-I signaling pathway [GO:1900246]; positive regulation of sprouting of injured axon [GO:0048687]; post-transcriptional regulation of gene expression [GO:0010608]; regulation of chromosome segregation [GO:0051983]; regulation of intracellular mRNA localization [GO:1904580]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of mRNA stability [GO:0043488]; regulation of translation [GO:0006417]; respiratory electron transport chain [GO:0022904]; skeletal system development [GO:0001501]; stress granule assembly [GO:0034063] | cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; neuronal cell body [GO:0043025]; nuclear membrane [GO:0031965]; perinuclear region of cytoplasm [GO:0048471] | lncRNA binding [GO:0106222]; miRNA binding [GO:0035198]; mRNA 3'-UTR binding [GO:0003730]; pumilio-response element binding [GO:0062104]; RNA binding [GO:0003723] | 9294.86012794897 | 0.0611931508312223 | 0.986435687529068 | 1 |
| Q9Y606 | Q9Y606 | PUS1_HUMAN | Pseudouridylate synthase 1 homolog (EC 5.4.99.-) (tRNA pseudouridine synthase 1) (EC 5.4.99.12) (tRNA pseudouridine(38-40) synthase) (tRNA pseudouridylate synthase I) (tRNA-uridine isomerase I) | PUS1 | mitochondrial tRNA pseudouridine synthesis [GO:0070902]; mRNA processing [GO:0006397]; mRNA pseudouridine synthesis [GO:1990481]; RNA splicing [GO:0008380]; tRNA pseudouridine synthesis [GO:0031119] | cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] | pseudouridine synthase activity [GO:0009982]; RNA binding [GO:0003723]; steroid receptor RNA activator RNA binding [GO:0002153]; tRNA binding [GO:0000049]; tRNA pseudouridine synthase activity [GO:0106029] | 10714.48072055195 | -0.0288622658869302 | 0.9965721627126 | 1 |
| Q96PZ0 | Q96PZ0 | PUS7_HUMAN | Pseudouridylate synthase 7 homolog (EC 5.4.99.-) | PUS7 | mRNA processing [GO:0006397]; mRNA pseudouridine synthesis [GO:1990481]; negative regulation of translation [GO:0017148]; pseudouridine synthesis [GO:0001522]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mesoderm development [GO:2000380]; RNA splicing [GO:0008380]; tRNA pseudouridine synthesis [GO:0031119] | nucleus [GO:0005634] | enzyme binding [GO:0019899]; pseudouridine synthase activity [GO:0009982]; RNA binding [GO:0003723]; tRNA pseudouridine synthase activity [GO:0106029] | 3957.9701481000548 | -0.0176492479195725 | 0.999984836674198 | 1 |
| P11216 | P11216 | PYGB_HUMAN | Glycogen phosphorylase, brain form (EC 2.4.1.1) | PYGB | glycogen catabolic process [GO:0005980] | azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020] | glycogen phosphorylase activity [GO:0008184]; linear malto-oligosaccharide phosphorylase activity [GO:0102250]; pyridoxal phosphate binding [GO:0030170]; SHG alpha-glucan phosphorylase activity [GO:0102499] | 59362.8657139594 | -0.103674783318187 | 0.971639971626068 | 1 |
| P11217 | P11217 | PYGM_HUMAN | Glycogen phosphorylase, muscle form (EC 2.4.1.1) (Myophosphorylase) | PYGM | glycogen catabolic process [GO:0005980]; glycogen metabolic process [GO:0005977] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062] | glycogen phosphorylase activity [GO:0008184]; linear malto-oligosaccharide phosphorylase activity [GO:0102250]; nucleotide binding [GO:0000166]; pyridoxal phosphate binding [GO:0030170]; SHG alpha-glucan phosphorylase activity [GO:0102499] | 62095.62874145094 | -0.00569303392213655 | 0.999999999058611 | 1 |
| Q96PU8 | Q96PU8 | QKI_HUMAN | KH domain-containing RNA-binding protein QKI (Protein quaking) (Hqk) (HqkI) | QKI | intracellular mRNA localization [GO:0008298]; long-chain fatty acid biosynthetic process [GO:0042759]; microglia differentiation [GO:0014004]; mRNA processing [GO:0006397]; mRNA stabilization [GO:0048255]; mRNA transport [GO:0051028]; myelination [GO:0042552]; myofibroblast contraction [GO:1990764]; negative regulation of 3'-UTR-mediated mRNA stabilization [GO:1905869]; negative regulation of angiogenesis [GO:0016525]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of macrophage differentiation [GO:0045650]; negative regulation of miRNA catabolic process [GO:2000626]; negative regulation of translation [GO:0017148]; negative regulation of type I interferon production [GO:0032480]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of gene expression [GO:0010628]; positive regulation of myelination [GO:0031643]; positive regulation of oligodendrocyte differentiation [GO:0048714]; regulation of astrocyte differentiation [GO:0048710]; regulation of epithelial to mesenchymal transition [GO:0010717]; regulation of macrophage differentiation [GO:0045649]; regulation of mRNA splicing, via spliceosome [GO:0048024]; RNA splicing [GO:0008380]; spermatid development [GO:0007286]; vascular associated smooth muscle cell differentiation [GO:0035886]; vasculogenesis [GO:0001570] | cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; nucleus [GO:0005634]; synapse [GO:0045202] | DNA binding [GO:0003677]; internal N(7)-methylguanine-containing RNA reader activity [GO:0160089]; miRNA binding [GO:0035198]; mRNA 3'-UTR binding [GO:0003730]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; SH3 domain binding [GO:0017124]; transcription coactivator activity [GO:0003713] | 11014.64790375275 | 0.0133329493826268 | 0.999998675152413 | 1 |
| Q5T6V5 | Q5T6V5 | QNG1_HUMAN | Queuosine 5'-phosphate N-glycosylase/hydrolase (EC 3.2.2.-) (Q-nucleotide N-glycosylase 1) (Queuine salvage protein QNG1) (Queuosine-nucleotide N-glycosylase/hydrolase) | QNG1 | nucleoside salvage [GO:0043174]; tRNA-guanine transglycosylation [GO:0101030] | hydrolase activity [GO:0016787] | 10907.4521742293 | -0.0555614920509763 | 0.995576883773046 | 1 | |
| Q9NXS2 | Q9NXS2 | QPCTL_HUMAN | Glutaminyl-peptide cyclotransferase-like protein (EC 2.3.2.5) (Golgi-resident glutaminyl-peptide cyclotransferase) (isoQC) (gQC) | QPCTL | peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase [GO:0017186] | Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; membrane [GO:0016020] | glutaminyl-peptide cyclotransferase activity [GO:0016603]; zinc ion binding [GO:0008270] | 26383.83636212805 | -0.0676228411136313 | 0.989475804488513 | 1 |
| Q2TAL8 | Q2TAL8 | QRIC1_HUMAN | Transcriptional regulator QRICH1 (Glutamine-rich protein 1) | QRICH1 | endoplasmic reticulum unfolded protein response [GO:0030968]; integrated stress response signaling [GO:0140467]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; PERK-mediated unfolded protein response [GO:0036499]; positive regulation of apoptotic process [GO:0043065]; positive regulation of DNA-templated transcription [GO:0045893]; response to endoplasmic reticulum stress [GO:0034976] | cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886] | DNA binding [GO:0003677] | 6457.784611674165 | -0.070804880987862 | 0.981843135923255 | 1 |
| Q6IQ22 | Q6IQ22 | RAB12_HUMAN | Ras-related protein Rab-12 | RAB12 | autophagy [GO:0006914]; endocytic recycling [GO:0032456]; endosome to lysosome transport [GO:0008333]; Golgi vesicle fusion to target membrane [GO:0048210]; protein catabolic process [GO:0030163]; protein localization to plasma membrane [GO:0072659]; protein secretion [GO:0009306]; Rab protein signal transduction [GO:0032482]; regulation of exocytosis [GO:0017157]; vesicle docking involved in exocytosis [GO:0006904] | autophagosome [GO:0005776]; cytosol [GO:0005829]; endosome [GO:0005768]; Golgi membrane [GO:0000139]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; synaptic vesicle [GO:0008021]; trans-Golgi network transport vesicle [GO:0030140] | GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924] | 23964.1311749695 | 0.0443959543579766 | 0.914229571418823 | 1 |
| P51153 | P51153 | RAB13_HUMAN | Ras-related protein Rab-13 (Cell growth-inhibiting gene 4 protein) | RAB13 | bicellular tight junction assembly [GO:0070830]; cellular response to insulin stimulus [GO:0032869]; cortical actin cytoskeleton organization [GO:0030866]; endocytic recycling [GO:0032456]; endosomal transport [GO:0016197]; endothelial cell chemotaxis [GO:0035767]; establishment of Sertoli cell barrier [GO:0097368]; Golgi to plasma membrane transport [GO:0006893]; Golgi vesicle fusion to target membrane [GO:0048210]; neuron projection development [GO:0031175]; protein kinase A signaling [GO:0010737]; protein localization to cell leading edge [GO:1902463]; protein localization to plasma membrane [GO:0072659]; protein secretion [GO:0009306]; regulation of exocytosis [GO:0017157]; trans-Golgi network to recycling endosome transport [GO:0044795]; vesicle docking involved in exocytosis [GO:0006904] | bicellular tight junction [GO:0005923]; cell junction [GO:0030054]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endocytic vesicle [GO:0030139]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; insulin-responsive compartment [GO:0032593]; lamellipodium [GO:0030027]; lateral plasma membrane [GO:0016328]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; recycling endosome membrane [GO:0055038]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140] | GTP binding [GO:0005525]; GTPase activity [GO:0003924] | 26773.461349161247 | -0.00688096555560806 | 0.864915868771931 | 1 |
| Q9UL26 | Q9UL26 | RB22A_HUMAN | Ras-related protein Rab-22A (Rab-22) | RAB22A | endocytosis [GO:0006897]; endosome organization [GO:0007032]; intracellular protein transport [GO:0006886]; regulation of vesicle size [GO:0097494] | actin cytoskeleton [GO:0015629]; early endosome [GO:0005769]; endomembrane system [GO:0012505]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; late endosome [GO:0005770]; phagocytic vesicle [GO:0045335]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; ruffle [GO:0001726] | GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924] | 13605.990245177349 | -0.0547621704162496 | 0.983218529245936 | 1 |
| Q969Q5 | Q969Q5 | RAB24_HUMAN | Ras-related protein Rab-24 | RAB24 | autophagy [GO:0006914]; intracellular protein transport [GO:0006886] | autophagosome [GO:0005776]; cytosol [GO:0005829]; endomembrane system [GO:0012505]; endosome [GO:0005768]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667] | GTP binding [GO:0005525]; GTPase activity [GO:0003924] | 11425.3096136128 | 0.026789551193364 | 0.996669474348063 | 1 |
| Q8WUD1 | Q8WUD1 | RAB2B_HUMAN | Ras-related protein Rab-2B (EC 3.6.5.2) | RAB2B | defense response to virus [GO:0051607]; Golgi organization [GO:0007030]; innate immune response [GO:0045087]; macroautophagy [GO:0016236]; positive regulation of exocytosis [GO:0045921]; positive regulation of type I interferon production [GO:0032481]; protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192] | acrosomal vesicle [GO:0001669]; autophagosome membrane [GO:0000421]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; plasma membrane [GO:0005886] | GTP binding [GO:0005525]; GTPase activity [GO:0003924] | 23122.499698877553 | 0.0236330182391202 | 0.992294406494348 | 1 |
| Q13637 | Q13637 | RAB32_HUMAN | Ras-related protein Rab-32 | RAB32 | antigen processing and presentation [GO:0019882]; endosome to lysosome transport [GO:0008333]; endosome to melanosome transport [GO:0035646]; intracellular protein transport [GO:0006886]; melanosome assembly [GO:1903232]; melanosome organization [GO:0032438]; mitochondrion organization [GO:0007005]; phagosome maturation [GO:0090382]; phagosome-lysosome fusion [GO:0090385]; protein localization to membrane [GO:0072657] | cytosol [GO:0005829]; early endosome [GO:0005769]; endomembrane system [GO:0012505]; endoplasmic reticulum [GO:0005783]; late endosome [GO:0005770]; lysosome [GO:0005764]; melanosome [GO:0042470]; melanosome membrane [GO:0033162]; membrane [GO:0016020]; mitochondria-associated endoplasmic reticulum membrane [GO:0044233]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; phagocytic vesicle [GO:0045335]; phagocytic vesicle membrane [GO:0030670]; trans-Golgi network [GO:0005802] | AP-1 adaptor complex binding [GO:0035650]; AP-3 adaptor complex binding [GO:0035651]; BLOC-2 complex binding [GO:0036461]; GTP binding [GO:0005525]; GTP-dependent protein binding [GO:0030742]; GTPase activity [GO:0003924] | 81515.37945396549 | 0.0368806515068214 | 0.976352438693899 | 1 |
| Q15286 | Q15286 | RAB35_HUMAN | Ras-related protein Rab-35 (GTP-binding protein RAY) (Ras-related protein Rab-1C) | RAB35 | antigen processing and presentation [GO:0019882]; cellular response to nerve growth factor stimulus [GO:1990090]; endocytic recycling [GO:0032456]; endosomal transport [GO:0016197]; mitotic cytokinesis [GO:0000281]; neuron projection development [GO:0031175]; plasma membrane to endosome transport [GO:0048227]; protein localization [GO:0008104]; protein localization to endosome [GO:0036010]; protein transport [GO:0015031]; Rab protein signal transduction [GO:0032482] | cell projection membrane [GO:0031253]; clathrin-coated endocytic vesicle [GO:0045334]; clathrin-coated endocytic vesicle membrane [GO:0030669]; clathrin-coated pit [GO:0005905]; cytosol [GO:0005829]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; intercellular bridge [GO:0045171]; melanosome [GO:0042470]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038] | GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546] | 10901.577604900449 | -0.0253431156281181 | 0.996555665439315 | 1 |
| Q15042 | Q15042 | RB3GP_HUMAN | Rab3 GTPase-activating protein catalytic subunit (RAB3 GTPase-activating protein 130 kDa subunit) (Rab3-GAP p130) (Rab3-GAP) | RAB3GAP1 | brain development [GO:0007420]; camera-type eye development [GO:0043010]; establishment of protein localization to endoplasmic reticulum membrane [GO:0097051]; excitatory postsynaptic potential [GO:0060079]; face morphogenesis [GO:0060325]; hypothalamus development [GO:0021854]; lipid droplet organization [GO:0034389]; positive regulation of autophagosome assembly [GO:2000786]; positive regulation of endoplasmic reticulum tubular network organization [GO:1903373]; positive regulation of glutamate neurotransmitter secretion in response to membrane depolarization [GO:0061646]; positive regulation of GTPase activity [GO:0043547]; positive regulation of protein lipidation [GO:1903061]; regulation of calcium ion-dependent exocytosis of neurotransmitter [GO:1903233]; regulation of GTPase activity [GO:0043087]; regulation of short-term neuronal synaptic plasticity [GO:0048172] | cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum tubular network [GO:0071782]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; lipid droplet [GO:0005811]; postsynapse [GO:0098794]; protein-containing complex [GO:0032991] | GTPase activator activity [GO:0005096]; guanyl-nucleotide exchange factor activity [GO:0005085]; small GTPase binding [GO:0031267] | 10918.7825491762 | -0.12393095386516 | 0.99171821792665 | 1 |
| Q9H2M9 | Q9H2M9 | RBGPR_HUMAN | Rab3 GTPase-activating protein non-catalytic subunit (RGAP-iso) (Rab3 GTPase-activating protein 150 kDa subunit) (Rab3-GAP p150) (Rab3-GAP150) (Rab3-GAP regulatory subunit) | RAB3GAP2 | establishment of protein localization to endoplasmic reticulum membrane [GO:0097051]; intracellular protein transport [GO:0006886]; positive regulation of autophagosome assembly [GO:2000786]; positive regulation of endoplasmic reticulum tubular network organization [GO:1903373]; positive regulation of protein lipidation [GO:1903061]; regulation of GTPase activity [GO:0043087] | cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991] | enzyme activator activity [GO:0008047]; enzyme regulator activity [GO:0030234]; GTPase activator activity [GO:0005096]; small GTPase binding [GO:0031267] | 13405.2445667587 | -0.146779437557871 | 0.857003545732938 | 1 |
| Q15276 | Q15276 | RABE1_HUMAN | Rab GTPase-binding effector protein 1 (Rabaptin-4) (Rabaptin-5) (Rabaptin-5alpha) (Renal carcinoma antigen NY-REN-17) | RABEP1 | apoptotic process [GO:0006915]; endocytosis [GO:0006897]; Golgi to plasma membrane transport [GO:0006893]; membrane fusion [GO:0061025]; protein localization to ciliary membrane [GO:1903441]; protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192] | early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endosome [GO:0005768]; intracellular membrane-bounded organelle [GO:0043231]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037] | growth factor activity [GO:0008083]; GTPase activator activity [GO:0005096]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803] | 6489.929995923734 | 0.0218288137773936 | 0.999946895218964 | 1 |
| Q5R372 | Q5R372 | RBG1L_HUMAN | Rab GTPase-activating protein 1-like | RABGAP1L | endocytosis [GO:0006897]; protein transport [GO:0015031]; regulation of protein localization [GO:0032880] | early endosome [GO:0005769]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634] | GTPase activator activity [GO:0005096]; small GTPase binding [GO:0031267] | 7109.4825037918 | -0.132303548321248 | 0.861289615748844 | 1 |
| Q9UJ41 | Q9UJ41 | RABX5_HUMAN | Rab5 GDP/GTP exchange factor (RAP1) (Rabaptin-5-associated exchange factor for Rab5) (Rabex-5) | RABGEF1 | dendritic transport [GO:0098935]; Kit signaling pathway [GO:0038109]; mast cell degranulation [GO:0043303]; mast cell migration [GO:0097531]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of Kit signaling pathway [GO:1900235]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of mast cell activation [GO:0033004]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of Ras protein signal transduction [GO:0046580]; negative regulation of receptor-mediated endocytosis [GO:0048261]; protein targeting to membrane [GO:0006612]; protein transport [GO:0015031]; Ras protein signal transduction [GO:0007265]; receptor-mediated endocytosis [GO:0006898]; regulation of Fc receptor mediated stimulatory signaling pathway [GO:0060368] | cytosol [GO:0005829]; dendrite [GO:0030425]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; nucleolus [GO:0005730]; recycling endosome [GO:0055037] | DNA binding [GO:0003677]; guanyl-nucleotide exchange factor activity [GO:0005085]; small GTPase binding [GO:0031267]; ubiquitin protein ligase activity [GO:0061630]; zinc ion binding [GO:0008270] | 13192.6957763297 | 0.0597013183103132 | 0.902498355178121 | 1 |
| Q3YEC7 | Q3YEC7 | RABL6_HUMAN | Rab-like protein 6 (GTP-binding protein Parf) (Partner of ARF) (Rab-like protein 1) (RBEL1) | RABL6 | centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634] | GTP binding [GO:0005525] | 10736.4056579784 | 0.0304102416680581 | 0.988649160575133 | 1 | |
| P15153 | P15153 | RAC2_HUMAN | Ras-related C3 botulinum toxin substrate 2 (GX) (Small G protein) (p21-Rac2) | RAC2 | actin filament organization [GO:0007015]; bone resorption [GO:0045453]; cell projection assembly [GO:0030031]; chemotaxis [GO:0006935]; cortical cytoskeleton organization [GO:0030865]; engulfment of apoptotic cell [GO:0043652]; erythrocyte enucleation [GO:0043131]; establishment or maintenance of cell polarity [GO:0007163]; G protein-coupled receptor signaling pathway [GO:0007186]; lymphocyte aggregation [GO:0071593]; mast cell proliferation [GO:0070662]; motor neuron axon guidance [GO:0008045]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of mast cell proliferation [GO:0070668]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of protein targeting to mitochondrion [GO:1903955]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360]; regulation of cell-substrate adhesion [GO:0010810]; regulation of hydrogen peroxide metabolic process [GO:0010310]; regulation of mast cell chemotaxis [GO:0060753]; regulation of mast cell degranulation [GO:0043304]; regulation of neutrophil migration [GO:1902622]; regulation of respiratory burst [GO:0060263]; regulation of T cell proliferation [GO:0042129]; respiratory burst [GO:0045730]; signal transduction [GO:0007165]; small GTPase-mediated signal transduction [GO:0007264] | cytoskeleton [GO:0005856]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; mitochondrial outer membrane [GO:0005741]; NADPH oxidase complex [GO:0043020]; nuclear envelope [GO:0005635]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886] | GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein kinase binding [GO:0019901]; protein kinase regulator activity [GO:0019887] | 153389.7308205065 | -0.0807566577619722 | 0.964698640399762 | 1 |
| P78406 | P78406 | RAE1L_HUMAN | mRNA export factor RAE1 (Rae1 protein homolog) (mRNA-associated protein mrnp 41) | RAE1 | cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to organic cyclic compound [GO:0071407]; mRNA export from nucleus [GO:0006406]; nucleocytoplasmic transport [GO:0006913]; regulation of mitotic spindle organization [GO:0060236]; RNA export from nucleus [GO:0006405]; transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery [GO:0000972] | cytoplasm [GO:0005737]; fibrillar center [GO:0001650]; mitotic spindle pole [GO:0097431]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] | microtubule binding [GO:0008017]; RNA binding [GO:0003723]; ubiquitin binding [GO:0043130] | 12976.530729645248 | -0.0644858622966918 | 0.903360568674836 | 1 |
| P11234 | P11234 | RALB_HUMAN | Ras-related protein Ral-B (EC 3.6.5.2) | RALB | apoptotic process [GO:0006915]; cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to exogenous dsRNA [GO:0071360]; cellular response to starvation [GO:0009267]; negative regulation of protein binding [GO:0032091]; positive regulation of autophagosome assembly [GO:2000786]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of protein binding [GO:0032092]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; Ras protein signal transduction [GO:0007265]; receptor internalization [GO:0031623]; regulation of exocyst assembly [GO:0001928]; regulation of exocyst localization [GO:0060178]; signal transduction [GO:0007165] | extracellular exosome [GO:0070062]; midbody [GO:0030496]; plasma membrane [GO:0005886] | ATPase binding [GO:0051117]; G protein activity [GO:0003925]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; ubiquitin protein ligase binding [GO:0031625] | 109450.06296572849 | -0.0204740401137124 | 0.99637122160111 | 1 |
| Q15311 | Q15311 | RBP1_HUMAN | RalA-binding protein 1 (RalBP1) (76 kDa Ral-interacting protein) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase) (EC 7.6.2.2, EC 7.6.2.3) (Ral-interacting protein 1) | RALBP1 | chemotaxis [GO:0006935]; doxorubicin transport [GO:1900753]; endocytosis [GO:0006897]; positive regulation of GTPase activity [GO:0043547]; positive regulation of mitochondrial fission [GO:0090141]; positive regulation of protein phosphorylation [GO:0001934]; regulation of Cdc42 protein signal transduction [GO:0032489]; regulation of GTPase activity [GO:0043087]; regulation of small GTPase mediated signal transduction [GO:0051056]; small GTPase-mediated signal transduction [GO:0007264]; transmembrane transport [GO:0055085]; xenobiotic detoxification by transmembrane export across the plasma membrane [GO:1990961] | cytosol [GO:0005829]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; spindle pole [GO:0000922] | ABC-type glutathione S-conjugate transporter activity [GO:0015431]; ABC-type xenobiotic transporter activity [GO:0008559]; ATP binding [GO:0005524]; ATPase-coupled transmembrane transporter activity [GO:0042626]; GTPase activator activity [GO:0005096]; small GTPase binding [GO:0031267]; transmembrane transporter activity [GO:0022857]; xenobiotic transmembrane transporter activity [GO:0042910] | 2339.816185760335 | 0.0884698619484606 | 0.9971259205489 | 1 |
| Q6VN20 | Q6VN20 | RBP10_HUMAN | Ran-binding protein 10 (RanBP10) | RANBP10 | cytoskeleton organization [GO:0007010] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; ubiquitin ligase complex [GO:0000151] | 5449.399982669795 | -0.0117236571974339 | 0.999113475682337 | 1 | |
| Q9H6Z4 | Q9H6Z4 | RANB3_HUMAN | Ran-binding protein 3 (RanBP3) | RANBP3 | protein export from nucleus [GO:0006611] | cytoplasm [GO:0005737]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] | GTPase activator activity [GO:0005096]; R-SMAD binding [GO:0070412]; small GTPase binding [GO:0031267] | 37604.67412045525 | 0.0286010274376931 | 0.869364463032375 | 1 |
| P61224 | P61224 | RAP1B_HUMAN | Ras-related protein Rap-1b (EC 3.6.5.2) (GTP-binding protein smg p21B) | RAP1B | calcium-ion regulated exocytosis [GO:0017156]; cell population proliferation [GO:0008283]; cellular response to cAMP [GO:0071320]; establishment of endothelial barrier [GO:0061028]; establishment of localization in cell [GO:0051649]; modification of postsynaptic structure [GO:0099010]; negative regulation of calcium ion-dependent exocytosis [GO:0045955]; negative regulation of synaptic vesicle exocytosis [GO:2000301]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of integrin activation [GO:0033625]; Rap protein signal transduction [GO:0032486]; regulation of cell junction assembly [GO:1901888]; regulation of establishment of cell polarity [GO:2000114] | azurophil granule membrane [GO:0035577]; cell-cell junction [GO:0005911]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; lipid droplet [GO:0005811]; membrane [GO:0016020]; plasma membrane [GO:0005886] | G protein activity [GO:0003925]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein-containing complex binding [GO:0044877] | 113991.068381556 | 0.17659741260932 | 0.79018186397453 | 1 |
| P10114 | P10114 | RAP2A_HUMAN | Ras-related protein Rap-2a (EC 3.6.5.2) (RbBP-30) | RAP2A | actin cytoskeleton organization [GO:0030036]; cellular response to xenobiotic stimulus [GO:0071466]; establishment of protein localization [GO:0045184]; microvillus assembly [GO:0030033]; negative regulation of cell migration [GO:0030336]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein phosphorylation [GO:0001934]; protein localization [GO:0008104]; protein localization to plasma membrane [GO:0072659]; Rap protein signal transduction [GO:0032486]; regulation of dendrite morphogenesis [GO:0048814]; regulation of JNK cascade [GO:0046328]; regulation of postsynaptic membrane neurotransmitter receptor levels [GO:0099072]; regulation of synapse assembly [GO:0051963] | cytosol [GO:0005829]; midbody [GO:0030496]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; recycling endosome membrane [GO:0055038]; Schaffer collateral - CA1 synapse [GO:0098685]; synaptic membrane [GO:0097060] | G protein activity [GO:0003925]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287] | 8451.29523672872 | 0.00883033421983375 | 0.972847739416307 | 1 |
| P61225 | P61225 | RAP2B_HUMAN | Ras-related protein Rap-2b (EC 3.6.5.2) | RAP2B | negative regulation of cell migration [GO:0030336]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; positive regulation of protein autophosphorylation [GO:0031954]; Rap protein signal transduction [GO:0032486]; regulation of protein tyrosine kinase activity [GO:0061097]; signal transduction [GO:0007165] | bicellular tight junction [GO:0005923]; cell-cell contact zone [GO:0044291]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821] | G protein activity [GO:0003925]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein domain specific binding [GO:0019904] | 39224.94584749975 | 0.0172046680794669 | 0.998938108716485 | 1 |
| P54136 | P54136 | SYRC_HUMAN | Arginine--tRNA ligase, cytoplasmic (EC 6.1.1.19) (Arginyl-tRNA synthetase) (ArgRS) | RARS1 | arginyl-tRNA aminoacylation [GO:0006420]; mitochondrial translation [GO:0032543]; tRNA aminoacylation for protein translation [GO:0006418] | aminoacyl-tRNA synthetase multienzyme complex [GO:0017101]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] | arginine binding [GO:0034618]; arginine-tRNA ligase activity [GO:0004814]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; tRNA binding [GO:0000049] | 64618.3440937495 | -0.0950589579230508 | 0.779289045332028 | 1 |
| O75884 | O75884 | RBBP9_HUMAN | Serine hydrolase RBBP9 (EC 3.-.-.-) (B5T-overexpressed gene protein) (Protein BOG) (Retinoblastoma-binding protein 10) (RBBP-10) (Retinoblastoma-binding protein 9) (RBBP-9) | RBBP9 | positive regulation of gene expression [GO:0010628]; response to nematode [GO:0009624]; type II pneumocyte differentiation [GO:0060510] | nucleoplasm [GO:0005654] | hydrolase activity [GO:0016787] | 7776.20510743418 | -0.186497962633186 | 0.93350803535407 | 1 |
| O43251 | O43251 | RFOX2_HUMAN | RNA binding protein fox-1 homolog 2 (Fox-1 homolog B) (Hexaribonucleotide-binding protein 2) (RNA-binding motif protein 9) (RNA-binding protein 9) (Repressor of tamoxifen transcriptional activity) | RBFOX2 | intracellular estrogen receptor signaling pathway [GO:0030520]; mRNA processing [GO:0006397]; negative regulation of DNA-templated transcription [GO:0045892]; nervous system development [GO:0007399]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of cell population proliferation [GO:0042127]; RNA metabolic process [GO:0016070]; RNA splicing [GO:0008380] | cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] | DNA-binding transcription factor binding [GO:0140297]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; transcription corepressor activity [GO:0003714] | 21241.964362868952 | 0.0726508721626787 | 0.923252426221991 | 1 |
| P98175 | P98175 | RBM10_HUMAN | RNA-binding protein 10 (G patch domain-containing protein 9) (RNA-binding motif protein 10) (RNA-binding protein S1-1) (S1-1) | RBM10 | 3'-UTR-mediated mRNA stabilization [GO:0070935]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular associated smooth muscle cell proliferation [GO:1904706]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; vascular associated smooth muscle cell apoptotic process [GO:1905288]; vascular associated smooth muscle cell proliferation [GO:1990874] | nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991] | identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; miRNA binding [GO:0035198]; RNA binding [GO:0003723] | 16503.67943853735 | 0.0841096997331312 | 0.937817052717594 | 1 |
| Q9NTZ6 | Q9NTZ6 | RBM12_HUMAN | RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN) | RBM12 | regulation of RNA splicing [GO:0043484] | nucleoplasm [GO:0005654]; ribonucleoprotein complex [GO:1990904] | RNA binding [GO:0003723] | 15570.56607112785 | 0.0345861482213639 | 0.995551204057343 | 1 |
| Q96PK6 | Q96PK6 | RBM14_HUMAN | RNA-binding protein 14 (Paraspeckle protein 2) (PSP2) (RNA-binding motif protein 14) (RRM-containing coactivator activator/modulator) (Synaptotagmin-interacting protein) (SYT-interacting protein) | RBM14 | activation of innate immune response [GO:0002218]; apoptotic process [GO:0006915]; centriole assembly [GO:0098534]; gastrulation [GO:0007369]; innate immune response [GO:0045087]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of centriole replication [GO:0046600]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of response to DNA integrity checkpoint signaling [GO:1902151]; response to hormone [GO:0009725]; transcription initiation-coupled chromatin remodeling [GO:0045815] | cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; transcription regulator complex [GO:0005667] | mRNA binding [GO:0003729]; nuclear receptor coactivator activity [GO:0030374]; RNA binding [GO:0003723]; splicing factor binding [GO:1990935] | 52627.7641288655 | 0.0360250364767781 | 0.999983425614641 | 1 |
| Q96T37 | Q96T37 | RBM15_HUMAN | RNA-binding protein 15 (One-twenty two protein 1) (RNA-binding motif protein 15) | RBM15 | branching involved in blood vessel morphogenesis [GO:0001569]; dosage compensation by inactivation of X chromosome [GO:0009048]; negative regulation of myeloid cell differentiation [GO:0045638]; placenta blood vessel development [GO:0060674]; positive regulation of transcription of Notch receptor target [GO:0007221]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of megakaryocyte differentiation [GO:0045652]; RNA methylation [GO:0001510]; spleen development [GO:0048536]; thrombopoietin-mediated signaling pathway [GO:0038163]; ventricular septum morphogenesis [GO:0060412] | nuclear membrane [GO:0031965]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA N6-methyladenosine methyltransferase complex [GO:0036396] | mRNA binding [GO:0003729]; RNA binding [GO:0003723] | 8051.496420298799 | -0.0537887297354288 | 0.999674140598965 | 1 |
| Q9Y4C8 | Q9Y4C8 | RBM19_HUMAN | Probable RNA-binding protein 19 (RNA-binding motif protein 19) | RBM19 | mRNA splicing, via spliceosome [GO:0000398]; positive regulation of embryonic development [GO:0040019] | chromosome [GO:0005694]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654] | mRNA binding [GO:0003729]; RNA binding [GO:0003723] | 4400.5926810032 | 0.147893193130016 | 0.952255866636425 | 1 |
| Q9NW64 | Q9NW64 | RBM22_HUMAN | Pre-mRNA-splicing factor RBM22 (RNA-binding motif protein 22) (Zinc finger CCCH domain-containing protein 16) | RBM22 | cellular response to xenobiotic stimulus [GO:0071466]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of RNA splicing [GO:0033120] | catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; Prp19 complex [GO:0000974]; U2-type catalytic step 1 spliceosome [GO:0071006]; U2-type catalytic step 2 spliceosome [GO:0071007] | calcium-dependent protein binding [GO:0048306]; metal ion binding [GO:0046872]; pre-mRNA binding [GO:0036002]; RNA binding [GO:0003723]; U6 snRNA binding [GO:0017070] | 15315.1817016043 | 0.0153993477617766 | 0.960837867385838 | 1 |
| P49756 | P49756 | RBM25_HUMAN | RNA-binding protein 25 (Arg/Glu/Asp-rich protein of 120 kDa) (RED120) (Protein S164) (RNA-binding motif protein 25) (RNA-binding region-containing protein 7) | RBM25 | mRNA processing [GO:0006397]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of apoptotic process [GO:0042981]; RNA splicing [GO:0008380] | cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; spliceosomal complex [GO:0005681] | mRNA binding [GO:0003729]; RNA binding [GO:0003723] | 11243.3851438859 | -0.0454164070180617 | 0.999994032372376 | 1 |
| Q9NW13 | Q9NW13 | RBM28_HUMAN | RNA-binding protein 28 (RNA-binding motif protein 28) | RBM28 | mRNA processing [GO:0006397]; RNA splicing [GO:0008380] | nucleolus [GO:0005730]; spliceosomal complex [GO:0005681] | mRNA binding [GO:0003729]; RNA binding [GO:0003723] | 9894.15553607406 | 0.0236944087926389 | 0.998729431351299 | 1 |
| Q9BWF3 | Q9BWF3 | RBM4_HUMAN | RNA-binding protein 4 (Lark homolog) (hLark) (RNA-binding motif protein 4) (RNA-binding motif protein 4a) | RBM4 | cap-independent translational initiation [GO:0002190]; circadian regulation of gene expression [GO:0032922]; circadian regulation of translation [GO:0097167]; enteroendocrine cell differentiation [GO:0035883]; entrainment of circadian clock by photoperiod [GO:0043153]; insulin secretion involved in cellular response to glucose stimulus [GO:0035773]; IRES-dependent translational initiation of linear mRNA [GO:0002192]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of translation [GO:0017148]; negative regulation of translation in response to stress [GO:0032055]; negative regulation of translational initiation [GO:0045947]; pancreas development [GO:0031016]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of translation [GO:0045727]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of insulin receptor signaling pathway [GO:0046626]; regulation of nucleocytoplasmic transport [GO:0046822]; response to arsenic-containing substance [GO:0046685]; RNA processing [GO:0006396] | cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471] | cyclin binding [GO:0030332]; miRNA binding [GO:0035198]; mRNA 3'-UTR binding [GO:0003730]; mRNA binding [GO:0003729]; pre-mRNA intronic binding [GO:0097157]; pre-mRNA intronic pyrimidine-rich binding [GO:0097158]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270] | 26509.212682284902 | 0.0880469146308497 | 0.952201755382178 | 1 |
| P52756 | P52756 | RBM5_HUMAN | RNA-binding protein 5 (Protein G15) (Putative tumor suppressor LUCA15) (RNA-binding motif protein 5) (Renal carcinoma antigen NY-REN-9) | RBM5 | apoptotic process [GO:0006915]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of apoptotic process [GO:0043065]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA processing [GO:0006396]; spliceosomal complex assembly [GO:0000245] | nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spliceosomal complex [GO:0005681] | DNA binding [GO:0003677]; metal ion binding [GO:0046872]; mRNA binding [GO:0003729]; RNA binding [GO:0003723] | 3227.399942025865 | 0.111456205410002 | 0.880349681331441 | 1 |
| P78332 | P78332 | RBM6_HUMAN | RNA-binding protein 6 (Lung cancer antigen NY-LU-12) (Protein G16) (RNA-binding motif protein 6) (RNA-binding protein DEF-3) | RBM6 | mRNA splicing, via spliceosome [GO:0000398]; RNA processing [GO:0006396] | nucleus [GO:0005634] | DNA binding [GO:0003677]; RNA binding [GO:0003723] | 5608.76821641312 | 0.038736111175774 | 0.854218408244666 | 1 |
| Q6XE24 | Q6XE24 | RBMS3_HUMAN | RNA-binding motif, single-stranded-interacting protein 3 | RBMS3 | defense response to tumor cell [GO:0002357]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of gene expression [GO:0010629]; positive regulation of gene expression [GO:0010628] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904] | mRNA 3'-UTR AU-rich region binding [GO:0035925]; mRNA 3'-UTR binding [GO:0003730]; poly(A) binding [GO:0008143]; poly(U) RNA binding [GO:0008266] | 13494.50042442515 | -0.133352350338879 | 0.853277373561717 | 1 |
| Q93062 | Q93062 | RBPMS_HUMAN | RNA-binding protein with multiple splicing (RBP-MS) (RBPMS) (Heart and RRM expressed sequence) (Hermes) | RBPMS | protein-containing complex assembly [GO:0065003]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; response to oxidative stress [GO:0006979]; RNA processing [GO:0006396]; SMAD protein signal transduction [GO:0060395] | cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932] | molecular adaptor activity [GO:0060090]; mRNA 3'-UTR binding [GO:0003730]; mRNA binding [GO:0003729]; mRNA CDS binding [GO:1990715]; pre-mRNA intronic binding [GO:0097157]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; transcription coactivator activity [GO:0003713] | 14360.307503638749 | 0.0696472999807004 | 0.981021728388918 | 1 |
| P18754 | P18754 | RCC1_HUMAN | Regulator of chromosome condensation (Cell cycle regulatory protein) (Chromosome condensation protein 1) | RCC1 | cell division [GO:0051301]; chromosome segregation [GO:0007059]; G1/S transition of mitotic cell cycle [GO:0000082]; mitotic nuclear membrane reassembly [GO:0007084]; mitotic spindle organization [GO:0007052]; regulation of mitotic nuclear division [GO:0007088]; spindle assembly [GO:0051225]; viral process [GO:0016032] | chromatin [GO:0000785]; chromosome [GO:0005694]; condensed nuclear chromosome [GO:0000794]; cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991] | chromatin binding [GO:0003682]; guanyl-nucleotide exchange factor activity [GO:0005085]; histone binding [GO:0042393]; nucleosomal DNA binding [GO:0031492]; nucleosome binding [GO:0031491]; protein heterodimerization activity [GO:0046982]; small GTPase binding [GO:0031267]; sulfate binding [GO:0043199] | 14749.4434762246 | -0.0506614788762609 | 0.972829029858852 | 1 |
| Q96D15 | Q96D15 | RCN3_HUMAN | Reticulocalbin-3 (EF-hand calcium-binding protein RLP49) | RCN3 | collagen biosynthetic process [GO:0032964]; ERAD pathway [GO:0036503]; lung epithelium development [GO:0060428]; phospholipid homeostasis [GO:0055091]; positive regulation of peptidase activity [GO:0010952]; protein secretion [GO:0009306]; protein transport [GO:0015031]; regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction [GO:0051896]; surfactant homeostasis [GO:0043129] | endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; intracellular membrane-bounded organelle [GO:0043231] | calcium ion binding [GO:0005509] | 303561.534167569 | 0.0683364904878574 | 0.996202625349925 | 1 |
| Q8IZV5 | Q8IZV5 | RDH10_HUMAN | Retinol dehydrogenase 10 (EC 1.1.1.300) (Short chain dehydrogenase/reductase family 16C member 4) | RDH10 | bud elongation involved in lung branching [GO:0060449]; ear development [GO:0043583]; embryonic camera-type eye development [GO:0031076]; embryonic forelimb morphogenesis [GO:0035115]; embryonic viscerocranium morphogenesis [GO:0048703]; gonad development [GO:0008406]; in utero embryonic development [GO:0001701]; metanephros development [GO:0001656]; neural crest cell development [GO:0014032]; nose development [GO:0043584]; positive regulation of retinoic acid biosynthetic process [GO:1900054]; primary lung bud formation [GO:0060431]; retinal metabolic process [GO:0042574]; retinoic acid biosynthetic process [GO:0002138]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; visual perception [GO:0007601] | cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; lipid droplet [GO:0005811]; membrane [GO:0016020] | NAD-retinol dehydrogenase activity [GO:0004745]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616] | 20697.11445149815 | 0.0451616434318154 | 0.939676391680701 | 1 |
| Q8NBN7 | Q8NBN7 | RDH13_HUMAN | Retinol dehydrogenase 13 (EC 1.1.1.300) (Short chain dehydrogenase/reductase family 7C member 3) | RDH13 | eye photoreceptor cell development [GO:0042462]; response to high light intensity [GO:0009644]; retina layer formation [GO:0010842]; retinal metabolic process [GO:0042574] | mitochondrial inner membrane [GO:0005743] | NADP-retinol dehydrogenase activity [GO:0052650] | 4864.823804489684 | 0.0381089600560172 | 0.997085878286489 | 1 |
| P35241 | P35241 | RADI_HUMAN | Radixin | RDX | apical protein localization [GO:0045176]; barbed-end actin filament capping [GO:0051016]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to thyroid hormone stimulus [GO:0097067]; establishment of endothelial barrier [GO:0061028]; establishment of protein localization to plasma membrane [GO:0061951]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of cell size [GO:0045792]; negative regulation of GTPase activity [GO:0034260]; negative regulation of homotypic cell-cell adhesion [GO:0034111]; positive regulation of cell migration [GO:0030335]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein localization to early endosome [GO:1902966]; protein kinase A signaling [GO:0010737]; protein localization to plasma membrane [GO:0072659]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; regulation of organelle assembly [GO:1902115]; regulation of Rap protein signal transduction [GO:0032487]; regulation of ruffle assembly [GO:1900027] | adherens junction [GO:0005912]; apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; cell periphery [GO:0071944]; cell tip [GO:0051286]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; midbody [GO:0030496]; plasma membrane [GO:0005886]; stereocilium base [GO:0120044]; T-tubule [GO:0030315] | actin binding [GO:0003779]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; cell adhesion molecule binding [GO:0050839]; protein kinase A binding [GO:0051018]; RNA binding [GO:0003723] | 107287.32188377151 | -0.054028284900736 | 0.999958371395791 | 1 |
| Q9P260 | Q9P260 | RELCH_HUMAN | RAB11-binding protein RELCH (LisH domain and HEAT repeat-containing protein KIAA1468) (RAB11 binding and LisH domain, coiled-coil and HEAT repeat-containing) (RAB11-binding protein containing LisH, coiled-coil, and HEAT repeats) | RELCH | intracellular cholesterol transport [GO:0032367] | recycling endosome [GO:0055037]; trans-Golgi network [GO:0005802] | 6042.83658056182 | -0.0385012001587139 | 0.999534577113909 | 1 | |
| Q96D71 | Q96D71 | REPS1_HUMAN | RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1) | REPS1 | clathrin-dependent synaptic vesicle endocytosis [GO:0150007]; endocytosis [GO:0006897]; endosomal transport [GO:0016197] | clathrin-coated pit [GO:0005905]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; intracellular vesicle [GO:0097708]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734] | calcium ion binding [GO:0005509]; molecular adaptor activity [GO:0060090]; SH3 domain binding [GO:0017124] | 4956.20024348935 | 0.162247105111727 | 0.844952490022014 | 1 |
| O15258 | O15258 | RER1_HUMAN | Protein RER1 | RER1 | positive regulation of protein localization to plasma membrane [GO:1903078]; protein retention in ER lumen [GO:0006621]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340] | cell surface [GO:0009986]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; plasma membrane [GO:0005886] | acetylcholine receptor binding [GO:0033130] | 168050.865859238 | 0.0271815335337493 | 0.999973858227524 | 1 |
| Q6NUM9 | Q6NUM9 | RETST_HUMAN | All-trans-retinol 13,14-reductase (EC 1.3.99.23) (All-trans-13,14-dihydroretinol saturase) (RetSat) (PPAR-alpha-regulated and starvation-induced gene protein) | RETSAT | retinol metabolic process [GO:0042572] | endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; nuclear membrane [GO:0031965]; nuclear outer membrane [GO:0005640] | all-trans-retinol 13,14-reductase activity [GO:0051786] | 19036.343254755848 | 0.0226496393636132 | 0.999999796196984 | 1 |
| Q9Y3B8 | Q9Y3B8 | ORN_HUMAN | Oligoribonuclease, mitochondrial (EC 3.1.15.-) (RNA exonuclease 2 homolog) (Small fragment nuclease) | REXO2 | nucleobase-containing compound metabolic process [GO:0006139]; nucleotide metabolic process [GO:0009117] | cytoplasm [GO:0005737]; focal adhesion [GO:0005925]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleus [GO:0005634] | 3'-5' exonuclease activity [GO:0008408]; 3'-5'-DNA exonuclease activity [GO:0008296]; 3'-5'-RNA exonuclease activity [GO:0000175]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676] | 45830.193355764306 | 0.103418799125934 | 0.657584384840646 | 1 |
| P35249 | P35249 | RFC4_HUMAN | Replication factor C subunit 4 (Activator 1 37 kDa subunit) (A1 37 kDa subunit) (Activator 1 subunit 4) (Replication factor C 37 kDa subunit) (RF-C 37 kDa subunit) (RFC37) | RFC4 | DNA duplex unwinding [GO:0032508]; DNA repair [GO:0006281]; DNA strand elongation involved in DNA replication [GO:0006271]; DNA-templated DNA replication [GO:0006261]; positive regulation of DNA-directed DNA polymerase activity [GO:1900264] | Ctf18 RFC-like complex [GO:0031390]; DNA replication factor C complex [GO:0005663]; Elg1 RFC-like complex [GO:0031391]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] | ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; DNA binding [GO:0003677]; DNA clamp loader activity [GO:0003689] | 3097.466202649815 | 0.314048766848629 | 0.762626635327868 | 1 |
| Q6ZTI6 | Q6ZTI6 | RFLA_HUMAN | Refilin-A (Regulator of filamin protein A) (RefilinA) | RFLNA | actin filament bundle organization [GO:0061572]; negative regulation of bone mineralization involved in bone maturation [GO:1900158]; negative regulation of chondrocyte development [GO:0061182]; skeletal system morphogenesis [GO:0048705] | actin filament bundle [GO:0032432]; cytoplasm [GO:0005737] | filamin binding [GO:0031005] | 9867.04745701639 | -0.20137886474174 | 0.682886086134781 | 1 |
| Q8TEB9 | Q8TEB9 | RHBL4_HUMAN | Rhomboid-related protein 4 (RRP4) (EC 3.4.21.105) (Rhomboid domain-containing protein 1) (Rhomboid-like protein 4) | RHBDD1 | apoptotic process [GO:0006915]; cellular response to unfolded protein [GO:0034620]; cellular response to UV [GO:0034644]; ERAD pathway [GO:0036503]; membrane protein intracellular domain proteolysis [GO:0031293]; membrane protein proteolysis [GO:0033619]; membrane protein proteolysis involved in retrograde protein transport, ER to cytosol [GO:1904211]; negative regulation of apoptotic process [GO:0043066]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein processing [GO:0010954]; positive regulation of secretion [GO:0051047]; post-translational protein modification [GO:0043687]; spermatid differentiation [GO:0048515] | endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum quality control compartment [GO:0044322]; mitochondrial membrane [GO:0031966] | endopeptidase activity [GO:0004175]; serine-type endopeptidase activity [GO:0004252] | 8308.22171647484 | -0.102635393652398 | 0.774755018354429 | 1 |
| P62745 | P62745 | RHOB_HUMAN | Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6) | RHOB | actin filament organization [GO:0007015]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; cell adhesion [GO:0007155]; cell differentiation [GO:0030154]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to ionizing radiation [GO:0071479]; endosome to lysosome transport [GO:0008333]; endothelial tube morphogenesis [GO:0061154]; intracellular protein transport [GO:0006886]; mitotic cytokinesis [GO:0000281]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell migration [GO:0030336]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of endothelial cell migration [GO:0010595]; regulation of cell migration [GO:0030334]; regulation of modification of postsynaptic structure [GO:0099159]; Rho protein signal transduction [GO:0007266]; signal transduction [GO:0007165] | cleavage furrow [GO:0032154]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; late endosome membrane [GO:0031902]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; Schaffer collateral - CA1 synapse [GO:0098685] | GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein kinase binding [GO:0019901] | 15364.8356109317 | -0.0968686145026533 | 0.866461223481918 | 1 |
| Q9NPQ8 | Q9NPQ8 | RIC8A_HUMAN | Synembryn-A (Protein Ric-8A) | RIC8A | adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; basement membrane organization [GO:0071711]; cell migration involved in gastrulation [GO:0042074]; cell-cell adhesion involved in gastrulation [GO:0070586]; G protein-coupled receptor signaling pathway [GO:0007186]; in utero embryonic development [GO:0001701]; vasculature development [GO:0001944]; visual learning [GO:0008542] | cytoplasm [GO:0005737]; plasma membrane [GO:0005886] | G-protein alpha-subunit binding [GO:0001965]; guanyl-nucleotide exchange factor activity [GO:0005085] | 23042.7516181916 | -0.0468449645080953 | 0.992453413401554 | 1 |
| Q13671 | Q13671 | RIN1_HUMAN | Ras and Rab interactor 1 (Ras inhibitor JC99) (Ras interaction/interference protein 1) | RIN1 | endocytosis [GO:0006897]; signal transduction [GO:0007165] | cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; endocytic vesicle [GO:0030139]; plasma membrane [GO:0005886] | GTPase activator activity [GO:0005096]; guanyl-nucleotide exchange factor activity [GO:0005085]; small GTPase binding [GO:0031267] | 6400.847861237549 | -0.041770339743503 | 0.999993760314347 | 1 |
| Q6NUQ1 | Q6NUQ1 | RINT1_HUMAN | RAD50-interacting protein 1 (RAD50 interactor 1) (HsRINT-1) (RINT-1) | RINT1 | endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; mitotic G2 DNA damage checkpoint signaling [GO:0007095]; protein transport [GO:0015031]; regulation of ER to Golgi vesicle-mediated transport [GO:0060628]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890] | cytosol [GO:0005829]; Dsl1/NZR complex [GO:0070939]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789] | 4080.207311988695 | 0.177578583981183 | 0.71156480279267 | 1 | |
| Q9H6W3 | Q9H6W3 | RIOX1_HUMAN | Ribosomal oxygenase 1 (60S ribosomal protein L8 histidine hydroxylase) (Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66) (EC 1.14.11.27, EC 1.14.11.79) (Myc-associated protein with JmjC domain) (Nucleolar protein 66) (hsNO66) (Ribosomal oxygenase NO66) (ROX) | RIOX1 | negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of osteoblast differentiation [GO:0045668] | nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] | 2-oxoglutarate-dependent dioxygenase activity [GO:0016706]; histone H3K36 demethylase activity [GO:0051864]; histone H3K36me/H3K36me2 demethylase activity [GO:0140680]; histone H3K4 demethylase activity [GO:0032453]; histone H3K4me/H3K4me2/H3K4me3 demethylase activity [GO:0034647]; iron ion binding [GO:0005506]; peptidyl-histidine dioxygenase activity [GO:0036139]; protein demethylase activity [GO:0140457] | 6087.1935719137 | -0.0648855571144918 | 0.736956269831255 | 1 |
| Q96TC7 | Q96TC7 | RMD3_HUMAN | Regulator of microtubule dynamics protein 3 (RMD-3) (hRMD-3) (Cerebral protein 10) (Protein FAM82A2) (Protein FAM82C) (Protein tyrosine phosphatase-interacting protein 51) (TCPTP-interacting protein 51) | RMDN3 | apoptotic process [GO:0006915]; cell differentiation [GO:0030154]; intracellular calcium ion homeostasis [GO:0006874] | cytoplasm [GO:0005737]; intercellular bridge [GO:0045171]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; mitotic spindle pole [GO:0097431]; nucleus [GO:0005634]; organelle membrane contact site [GO:0044232]; spindle microtubule [GO:0005876] | microtubule binding [GO:0008017] | 9025.355798386685 | -0.0621070901152259 | 0.739817813189599 | 1 |
| Q05823 | Q05823 | RN5A_HUMAN | 2-5A-dependent ribonuclease (2-5A-dependent RNase) (EC 3.1.26.-) (Ribonuclease 4) (Ribonuclease L) (RNase L) | RNASEL | defense response to virus [GO:0051607]; fat cell differentiation [GO:0045444]; mRNA processing [GO:0006397]; negative regulation of viral genome replication [GO:0045071]; positive regulation of glucose import [GO:0046326]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein phosphorylation [GO:0006468]; regulation of mRNA stability [GO:0043488]; RNA processing [GO:0006396]; rRNA processing [GO:0006364] | cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; nuclear matrix [GO:0016363] | ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein kinase activity [GO:0004672]; ribonucleoprotein complex binding [GO:0043021]; RNA binding [GO:0003723]; RNA endonuclease activity [GO:0004521]; RNA nuclease activity [GO:0004540]; rRNA binding [GO:0019843] | 4091.35913717538 | -0.0520122875289335 | 0.761130282189684 | 1 |
| P61587 | P61587 | RND3_HUMAN | Rho-related GTP-binding protein RhoE (Protein MemB) (Rho family GTPase 3) (Rho-related GTP-binding protein Rho8) (Rnd3) | RND3 | actin cytoskeleton organization [GO:0030036]; actin filament organization [GO:0007015]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; regulation of actin cytoskeleton organization [GO:0032956]; signal transduction [GO:0007165]; small GTPase-mediated signal transduction [GO:0007264] | cytosol [GO:0005829]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; plasma membrane [GO:0005886] | GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein kinase binding [GO:0019901] | 9132.106947150889 | 0.0826129290214406 | 0.935224525426945 | 1 |
| Q9Y3C5 | Q9Y3C5 | RNF11_HUMAN | RING finger protein 11 | RNF11 | protein autoubiquitination [GO:0051865]; ubiquitin-dependent protein catabolic process [GO:0006511] | early endosome [GO:0005769]; extracellular exosome [GO:0070062]; nucleus [GO:0005634]; recycling endosome [GO:0055037]; ubiquitin ligase complex [GO:0000151] | DNA binding [GO:0003677]; ubiquitin protein ligase activity [GO:0061630]; zinc ion binding [GO:0008270] | 12660.494155244302 | 0.0322036432711158 | 0.967818826505031 | 1 |
| Q9UBS8 | Q9UBS8 | RNF14_HUMAN | E3 ubiquitin-protein ligase RNF14 (EC 2.3.2.31) (Androgen receptor-associated protein 54) (HFB30) (RING finger protein 14) | RNF14 | androgen receptor signaling pathway [GO:0030521]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein K6-linked ubiquitination [GO:0085020]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; protein-RNA covalent cross-linking repair [GO:0160127]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]; rescue of stalled ribosome [GO:0072344]; signal transduction [GO:0007165]; ubiquitin-dependent protein catabolic process [GO:0006511] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic ribosome [GO:0022626]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ubiquitin ligase complex [GO:0000151] | nuclear androgen receptor binding [GO:0050681]; transcription coactivator activity [GO:0003713]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-like protein transferase activity [GO:0019787]; zinc ion binding [GO:0008270] | 14452.25119825705 | -0.061598103654957 | 0.817023605745447 | 1 |
| Q8ND24 | Q8ND24 | RN214_HUMAN | RING finger protein 214 | RNF214 | metal ion binding [GO:0046872]; ubiquitin-protein transferase activity [GO:0004842] | 7358.896554267365 | -0.0167407954520154 | 0.995993697307089 | 1 | ||
| Q96EP0 | Q96EP0 | RNF31_HUMAN | E3 ubiquitin-protein ligase RNF31 (EC 2.3.2.31) (HOIL-1-interacting protein) (HOIP) (RING finger protein 31) (RING-type E3 ubiquitin transferase RNF31) (Zinc in-between-RING-finger ubiquitin-associated domain protein) | RNF31 | CD40 signaling pathway [GO:0023035]; defense response to bacterium [GO:0042742]; negative regulation of necroptotic process [GO:0060546]; positive regulation of canonical NF-kappaB signal transduction [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein targeting to mitochondrion [GO:1903955]; positive regulation of xenophagy [GO:1904417]; protein linear polyubiquitination [GO:0097039]; protein polyubiquitination [GO:0000209]; T cell receptor signaling pathway [GO:0050852] | CD40 receptor complex [GO:0035631]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; LUBAC complex [GO:0071797] | identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; K63-linked polyubiquitin modification-dependent protein binding [GO:0070530]; linear polyubiquitin binding [GO:1990450]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270] | 5268.669678688065 | -0.211469869708287 | 0.785481926008085 | 1 |
| O60942 | O60942 | MCE1_HUMAN | mRNA-capping enzyme (HCAP1) (HCE) [Includes: mRNA 5'-triphosphate monophosphatase (EC 3.6.1.74) (mRNA 5'-phosphatase); mRNA guanylyltransferase (EC 2.7.7.50) (GTP--RNA guanylyltransferase) (GTase)] | RNGTT | 7-methylguanosine mRNA capping [GO:0006370]; dephosphorylation [GO:0016311]; RNA processing [GO:0006396] | nucleoplasm [GO:0005654]; nucleus [GO:0005634] | ATP binding [GO:0005524]; GTP binding [GO:0005525]; inorganic triphosphate phosphatase activity [GO:0050355]; mRNA 5'-phosphatase activity [GO:0140818]; mRNA guanylyltransferase activity [GO:0004484]; polynucleotide 5'-phosphatase activity [GO:0004651]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; RNA guanylyltransferase activity [GO:0008192] | 2417.569871972685 | -0.261960890685481 | 0.930638666047858 | 1 |
| P13489 | P13489 | RINI_HUMAN | Ribonuclease inhibitor (Placental ribonuclease inhibitor) (Placental RNase inhibitor) (Ribonuclease/angiogenin inhibitor 1) (RAI) | RNH1 | cell migration [GO:0016477]; mRNA catabolic process [GO:0006402]; regulation of angiogenesis [GO:0045765]; regulation of Arp2/3 complex-mediated actin nucleation [GO:0034315]; regulation of inflammatory response [GO:0050727] | angiogenin-PRI complex [GO:0032311]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; lamellipodium [GO:0030027]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] | ribonuclease inhibitor activity [GO:0008428] | 81965.4476747131 | 0.109329146273608 | 0.807310680380336 | 1 |
| O43148 | O43148 | MCES_HUMAN | mRNA cap guanine-N7 methyltransferase (EC 2.1.1.56) (RG7MT1) (mRNA (guanine-N(7))-methyltransferase) (mRNA cap methyltransferase) (hCMT1) (hMet) (hcm1p) | RNMT | 7-methylguanosine mRNA capping [GO:0006370]; cellular response to leukemia inhibitory factor [GO:1990830] | fibrillar center [GO:0001650]; mRNA capping enzyme complex [GO:0031533]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; receptor complex [GO:0043235] | mRNA 5'-cap (guanine-N7-)-methyltransferase activity [GO:0004482]; RNA binding [GO:0003723] | 16798.48962207795 | -0.0763797039849292 | 0.897799358349086 | 1 |
| Q9H4A4 | Q9H4A4 | AMPB_HUMAN | Aminopeptidase B (AP-B) (EC 3.4.11.6) (Arginine aminopeptidase) (Arginyl aminopeptidase) | RNPEP | proteolysis [GO:0006508] | extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886] | aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; metalloaminopeptidase activity [GO:0070006]; metalloexopeptidase activity [GO:0008235]; zinc ion binding [GO:0008270] | 34717.326450769746 | 0.0497866083534088 | 0.997365998353288 | 1 |
| P15927 | P15927 | RFA2_HUMAN | Replication protein A 32 kDa subunit (RP-A p32) (Replication factor A protein 2) (RF-A protein 2) (Replication protein A 34 kDa subunit) (RP-A p34) | RPA2 | base-excision repair [GO:0006284]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; mismatch repair [GO:0006298]; mitotic G1 DNA damage checkpoint signaling [GO:0031571]; nucleotide-excision repair [GO:0006289]; protein localization to chromosome [GO:0034502]; regulation of DNA damage checkpoint [GO:2000001]; regulation of double-strand break repair via homologous recombination [GO:0010569]; telomere maintenance [GO:0000723] | chromatin [GO:0000785]; chromosome, telomeric region [GO:0000781]; DNA replication factor A complex [GO:0005662]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; site of double-strand break [GO:0035861] | damaged DNA binding [GO:0003684]; enzyme binding [GO:0019899]; G-rich strand telomeric DNA binding [GO:0098505]; protein phosphatase binding [GO:0019903]; single-stranded DNA binding [GO:0003697]; telomeric DNA binding [GO:0042162]; ubiquitin protein ligase binding [GO:0031625] | 16697.90433190095 | 0.0963805820603679 | 0.866543826748399 | 1 |
| Q9H7B2 | Q9H7B2 | RPF2_HUMAN | Ribosome production factor 2 homolog (Brix domain-containing protein 1) (Ribosome biogenesis protein RPF2 homolog) | RPF2 | maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000463]; protein localization to nucleolus [GO:1902570]; regulation of signal transduction by p53 class mediator [GO:1901796]; ribosomal large subunit biogenesis [GO:0042273] | chromosome [GO:0005694]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654] | 5S rRNA binding [GO:0008097]; RNA binding [GO:0003723]; rRNA binding [GO:0019843] | 9045.362062600576 | 0.0166495209066308 | 0.998797664527787 | 1 |
| P27635 | P27635 | RL10_HUMAN | Large ribosomal subunit protein uL16 (60S ribosomal protein L10) (Laminin receptor homolog) (Protein QM) (Ribosomal protein L10) (Tumor suppressor QM) | RPL10 | cytoplasmic translation [GO:0002181]; embryonic brain development [GO:1990403]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of translation [GO:0006417]; translation [GO:0006412] | cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; cytosolic ribosome [GO:0022626]; endoplasmic reticulum [GO:0005783]; membrane [GO:0016020]; nucleus [GO:0005634]; protein-containing complex [GO:0032991] | RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735]; translation regulator activity [GO:0045182] | 203318.069374351 | 0.03833681771621 | 0.970722545038774 | 1 |
| P61313 | P61313 | RL15_HUMAN | Large ribosomal subunit protein eL15 (60S ribosomal protein L15) | RPL15 | cytoplasmic translation [GO:0002181]; response to ethanol [GO:0045471]; translation [GO:0006412] | A band [GO:0031672]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; cytosolic ribosome [GO:0022626]; nucleus [GO:0005634]; ribosome [GO:0005840]; synapse [GO:0045202] | cadherin binding [GO:0045296]; RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735] | 409845.468848977 | 0.0470991538279618 | 0.913326632229953 | 1 |
| Q02543 | Q02543 | RL18A_HUMAN | Large ribosomal subunit protein eL20 (60S ribosomal protein L18a) | RPL18A | cytoplasmic translation [GO:0002181]; translation [GO:0006412] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; cytosolic ribosome [GO:0022626]; membrane [GO:0016020] | RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735] | 76767.76146044841 | 0.165157740757086 | 0.994567020460128 | 1 |
| Q6P5R6 | Q6P5R6 | RL22L_HUMAN | Ribosomal protein eL22-like (60S ribosomal protein L22-like 1) (Large ribosomal subunit protein eL22-like 1) | RPL22L1 | cytoplasmic translation [GO:0002181] | ribonucleoprotein complex [GO:1990904]; ribosome [GO:0005840] | RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735] | 14443.37980091455 | 0.105645330388112 | 0.790283252782257 | 1 |
| P47914 | P47914 | RL29_HUMAN | Large ribosomal subunit protein eL29 (60S ribosomal protein L29) (Cell surface heparin-binding protein HIP) | RPL29 | cytoplasmic translation [GO:0002181]; embryo implantation [GO:0007566]; translation [GO:0006412] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; cytosolic ribosome [GO:0022626]; membrane [GO:0016020] | cadherin binding [GO:0045296]; heparin binding [GO:0008201]; RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735] | 361762.86283070897 | -0.0747225838327206 | 0.823010461098189 | 1 |
| P39023 | P39023 | RL3_HUMAN | Large ribosomal subunit protein uL3 (60S ribosomal protein L3) (HIV-1 TAR RNA-binding protein B) (TARBP-B) | RPL3 | cellular response to interleukin-4 [GO:0071353]; cytoplasmic translation [GO:0002181]; translation [GO:0006412] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; cytosolic ribosome [GO:0022626]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; nucleolus [GO:0005730]; nucleus [GO:0005634]; protein-containing complex [GO:0032991] | RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735] | 133883.051897475 | 0.0192783798663063 | 0.999866901993166 | 1 |
| P62910 | P62910 | RL32_HUMAN | Large ribosomal subunit protein eL32 (60S ribosomal protein L32) | RPL32 | cytoplasmic translation [GO:0002181]; translation [GO:0006412] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; cytosolic ribosome [GO:0022626]; membrane [GO:0016020] | RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735] | 109174.19154972001 | 0.106893411103486 | 0.855972468489754 | 1 |
| P18077 | P18077 | RL35A_HUMAN | Large ribosomal subunit protein eL33 (60S ribosomal protein L35a) (Cell growth-inhibiting gene 33 protein) | RPL35A | cytoplasmic translation [GO:0002181]; ribosomal large subunit biogenesis [GO:0042273]; rRNA processing [GO:0006364]; translation [GO:0006412] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; cytosolic ribosome [GO:0022626]; extracellular exosome [GO:0070062]; membrane [GO:0016020] | RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049] | 204068.5781014295 | 0.065625230113642 | 0.774551124920606 | 1 |
| P63173 | P63173 | RL38_HUMAN | Large ribosomal subunit protein eL38 (60S ribosomal protein L38) | RPL38 | 90S preribosome assembly [GO:0034463]; axial mesoderm development [GO:0048318]; cytoplasmic translation [GO:0002181]; middle ear morphogenesis [GO:0042474]; ossification [GO:0001503]; protein-RNA complex assembly [GO:0022618]; regulation of translation [GO:0006417]; sensory perception of sound [GO:0007605]; skeletal system development [GO:0001501]; translation [GO:0006412] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; cytosolic ribosome [GO:0022626]; eukaryotic 80S initiation complex [GO:0033291]; focal adhesion [GO:0005925]; postsynaptic density [GO:0014069] | RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735] | 209874.01634481002 | 0.203518817305151 | 0.716770088752119 | 1 |
| P36578 | P36578 | RL4_HUMAN | Large ribosomal subunit protein uL4 (60S ribosomal protein L1) (60S ribosomal protein L4) | RPL4 | cytoplasmic translation [GO:0002181]; translation [GO:0006412] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; cytosolic ribosome [GO:0022626]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; rough endoplasmic reticulum [GO:0005791] | RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735] | 199859.98946415598 | -0.00668578501106122 | 0.999999999959598 | 1 |
| P46777 | P46777 | RL5_HUMAN | Large ribosomal subunit protein uL18 (60S ribosomal protein L5) | RPL5 | cytoplasmic translation [GO:0002181]; negative regulation of protein neddylation [GO:2000435]; negative regulation of ubiquitin protein ligase activity [GO:1904667]; negative regulation of ubiquitin-dependent protein catabolic process [GO:2000059]; positive regulation of gene expression [GO:0010628]; positive regulation of translation [GO:0045727]; protein stabilization [GO:0050821]; regulation of signal transduction by p53 class mediator [GO:1901796]; ribosomal large subunit assembly [GO:0000027]; ribosomal large subunit biogenesis [GO:0042273]; rRNA processing [GO:0006364]; translation [GO:0006412] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; cytosolic ribosome [GO:0022626]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904] | 5S rRNA binding [GO:0008097]; mRNA 3'-UTR binding [GO:0003730]; mRNA 5'-UTR binding [GO:0048027]; RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735]; ubiquitin ligase inhibitor activity [GO:1990948]; ubiquitin protein ligase binding [GO:0031625] | 339675.28217285697 | 0.0480743312411788 | 0.953682061469994 | 1 |
| Q6DKI1 | Q6DKI1 | RL7L_HUMAN | Ribosomal protein uL30-like (60S ribosomal protein L7-like 1) (Large ribosomal subunit protein uL30-like 1) | RPL7L1 | blastocyst formation [GO:0001825]; maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000463] | cytosolic large ribosomal subunit [GO:0022625]; nucleolus [GO:0005730] | RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735] | 17753.8893523181 | 0.0575740295146657 | 0.897101201556482 | 1 |
| P05388 | P05388 | RLA0_HUMAN | Large ribosomal subunit protein uL10 (60S acidic ribosomal protein P0) (60S ribosomal protein L10E) | RPLP0 | cytoplasmic translation [GO:0002181]; ribosome biogenesis [GO:0042254]; translation [GO:0006412] | cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; cytosolic ribosome [GO:0022626]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]; ribonucleoprotein complex [GO:1990904] | large ribosomal subunit rRNA binding [GO:0070180]; RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735] | 269369.913894652 | 0.099844551817789 | 0.667464969664613 | 1 |
| P04844 | P04844 | RPN2_HUMAN | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 (Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 63 kDa subunit) (RIBIIR) (Ribophorin II) (RPN-II) (Ribophorin-2) | RPN2 | protein modification process [GO:0036211]; protein N-linked glycosylation [GO:0006487]; protein N-linked glycosylation via asparagine [GO:0018279] | endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; nuclear body [GO:0016604]; oligosaccharyltransferase complex [GO:0008250] | 193290.782795593 | -0.0888182732883217 | 0.994377772001078 | 1 | |
| P78345 | P78345 | RPP38_HUMAN | Ribonuclease P protein subunit p38 (RNaseP protein p38) | RPP38 | rRNA processing [GO:0006364]; tRNA 5'-leader removal [GO:0001682] | fibrillar center [GO:0001650]; multimeric ribonuclease P complex [GO:0030681]; nucleolar ribonuclease P complex [GO:0005655]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; ribonuclease MRP complex [GO:0000172] | ribonuclease P activity [GO:0004526]; ribonuclease P RNA binding [GO:0033204] | 12518.79875308325 | -0.0328791996108793 | 0.935185802671817 | 1 |
| P62244 | P62244 | RS15A_HUMAN | Small ribosomal subunit protein uS8 (40S ribosomal protein S15a) | RPS15A | cytoplasmic translation [GO:0002181]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; response to virus [GO:0009615]; ribosomal small subunit biogenesis [GO:0042274]; translation [GO:0006412] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic ribosome [GO:0022626]; cytosolic small ribosomal subunit [GO:0022627]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; small-subunit processome [GO:0032040]; synapse [GO:0045202] | RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735] | 53657.7146565696 | 0.0598758077627833 | 0.98456851872292 | 1 |
| P62249 | P62249 | RS16_HUMAN | Small ribosomal subunit protein uS9 (40S ribosomal protein S16) | RPS16 | cellular response to leukemia inhibitory factor [GO:1990830]; cytoplasmic translation [GO:0002181]; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; ribosomal small subunit biogenesis [GO:0042274]; rRNA processing [GO:0006364]; translation [GO:0006412] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic ribosome [GO:0022626]; cytosolic small ribosomal subunit [GO:0022627]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; small ribosomal subunit [GO:0015935]; small-subunit processome [GO:0032040]; synapse [GO:0045202] | RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735] | 239948.18750253198 | 0.136570229163175 | 0.755519030533247 | 1 |
| P63220 | P63220 | RS21_HUMAN | Small ribosomal subunit protein eS21 (40S ribosomal protein S21) | RPS21 | cytoplasmic translation [GO:0002181]; endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000447]; endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000461]; translation [GO:0006412] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic ribosome [GO:0022626]; cytosolic small ribosomal subunit [GO:0022627]; nucleoplasm [GO:0005654]; rough endoplasmic reticulum [GO:0005791]; small ribosomal subunit [GO:0015935]; synapse [GO:0045202] | RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735] | 117509.467668147 | -0.0354362393458036 | 0.960175773050839 | 1 |
| P42677 | P42677 | RS27_HUMAN | Small ribosomal subunit protein eS27 (40S ribosomal protein S27) (Metallopan-stimulin 1) (MPS-1) | RPS27 | cytoplasmic translation [GO:0002181]; ribosomal small subunit assembly [GO:0000028]; ribosomal small subunit biogenesis [GO:0042274]; rRNA processing [GO:0006364]; translation [GO:0006412] | cytosol [GO:0005829]; cytosolic ribosome [GO:0022626]; cytosolic small ribosomal subunit [GO:0022627]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynaptic density [GO:0014069]; ribosome [GO:0005840]; small-subunit processome [GO:0032040] | DNA binding [GO:0003677]; RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270] | 179188.061562807 | -0.0719139149918682 | 0.950771750233516 | 1 |
| P62701 | P62701 | RS4X_HUMAN | Small ribosomal subunit protein eS4, X isoform (40S ribosomal protein S4) (SCR10) (Single copy abundant mRNA protein) | RPS4X | cytoplasmic translation [GO:0002181]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of translation [GO:0045727]; ribosomal small subunit biogenesis [GO:0042274]; translation [GO:0006412] | cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; cytosolic ribosome [GO:0022626]; cytosolic small ribosomal subunit [GO:0022627]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; ribonucleoprotein complex [GO:1990904]; ribosome [GO:0005840]; small ribosomal subunit [GO:0015935]; small-subunit processome [GO:0032040]; synapse [GO:0045202] | RNA binding [GO:0003723]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735] | 101128.59590386701 | 0.0950087129144256 | 0.714238678251788 | 1 |
| P22090 | P22090 | RS4Y1_HUMAN | Small ribosomal subunit protein eS4, Y isoform 1 (40S ribosomal protein S4) | RPS4Y1 | translation [GO:0006412] | cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribosome [GO:0005840] | RNA binding [GO:0003723]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735] | 45938.06425769265 | 0.0933286686642197 | 0.733146827965523 | 1 |
| Q7L523 | Q7L523 | RRAGA_HUMAN | Ras-related GTP-binding protein A (Rag A) (RagA) (EC 3.6.5.-) (Adenovirus E3 14.7 kDa-interacting protein 1) (FIP-1) | RRAGA | apoptotic process [GO:0006915]; cellular response to amino acid starvation [GO:0034198]; cellular response to amino acid stimulus [GO:0071230]; cellular response to nutrient levels [GO:0031669]; cellular response to starvation [GO:0009267]; glucose homeostasis [GO:0042593]; intracellular signal transduction [GO:0035556]; negative regulation of autophagy [GO:0010507]; positive regulation of TOR signaling [GO:0032008]; positive regulation of TORC1 signaling [GO:1904263]; protein localization [GO:0008104]; protein localization to lysosome [GO:0061462]; protein localization to membrane [GO:0072657]; tumor necrosis factor-mediated signaling pathway [GO:0033209] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; FNIP-folliculin RagC/D GAP [GO:1990877]; Gtr1-Gtr2 GTPase complex [GO:1990131]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] | GTP binding [GO:0005525]; GTPase activity [GO:0003924]; phosphoprotein binding [GO:0051219]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein-membrane adaptor activity [GO:0043495]; ubiquitin protein ligase binding [GO:0031625] | 19667.6834752493 | -0.0210314768875498 | 0.994137335414081 | 1 |
| Q9HB90 | Q9HB90 | RRAGC_HUMAN | Ras-related GTP-binding protein C (Rag C) (RagC) (EC 3.6.5.-) (GTPase-interacting protein 2) (TIB929) | RRAGC | apoptotic process [GO:0006915]; cellular response to amino acid starvation [GO:0034198]; cellular response to amino acid stimulus [GO:0071230]; cellular response to nutrient levels [GO:0031669]; cellular response to starvation [GO:0009267]; DNA-templated transcription [GO:0006351]; negative regulation of autophagy [GO:0010507]; positive regulation of TORC1 signaling [GO:1904263]; protein localization [GO:0008104]; protein localization to lysosome [GO:0061462]; protein localization to membrane [GO:0072657]; regulation of TOR signaling [GO:0032006]; regulation of TORC1 signaling [GO:1903432]; response to amino acid [GO:0043200]; RNA splicing [GO:0008380]; small GTPase-mediated signal transduction [GO:0007264] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; FNIP-folliculin RagC/D GAP [GO:1990877]; Gtr1-Gtr2 GTPase complex [GO:1990131]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] | enzyme-substrate adaptor activity [GO:0140767]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; GTPase binding [GO:0051020]; magnesium ion binding [GO:0000287]; molecular adaptor activity [GO:0060090]; protein heterodimerization activity [GO:0046982]; protein-membrane adaptor activity [GO:0043495] | 14483.6068718809 | 0.0799359420577895 | 0.89382472902657 | 1 |
| P10301 | P10301 | RRAS_HUMAN | Ras-related protein R-Ras (EC 3.6.5.-) (p23) | RRAS | face morphogenesis [GO:0060325]; leukocyte differentiation [GO:0002521]; negative regulation of Schwann cell migration [GO:1900148]; positive regulation of angiogenesis [GO:0045766]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904906]; positive regulation of vasculogenesis [GO:2001214]; Ras protein signal transduction [GO:0007265]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction [GO:0051896]; Schwann cell migration [GO:0036135] | extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886] | GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein-containing complex binding [GO:0044877] | 125630.33059970301 | 0.109032282020589 | 0.902460228884667 | 1 |
| Q9P2E9 | Q9P2E9 | RRBP1_HUMAN | Ribosome-binding protein 1 (180 kDa ribosome receptor homolog) (RRp) (ES/130-related protein) (Ribosome receptor protein) | RRBP1 | osteoblast differentiation [GO:0001649]; protein transport [GO:0015031]; translation [GO:0006412] | endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; ribosome [GO:0005840] | RNA binding [GO:0003723]; signaling receptor activity [GO:0038023] | 405784.27994508203 | -0.0602111549250247 | 0.923699213653471 | 1 |
| P23921 | P23921 | RIR1_HUMAN | Ribonucleoside-diphosphate reductase large subunit (EC 1.17.4.1) (Ribonucleoside-diphosphate reductase subunit M1) (Ribonucleotide reductase large subunit) | RRM1 | 2'-deoxyribonucleotide biosynthetic process [GO:0009265]; cell proliferation in forebrain [GO:0021846]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA repair [GO:0006281]; DNA synthesis involved in DNA repair [GO:0000731]; male gonad development [GO:0008584]; mitochondrial DNA replication [GO:0006264]; positive regulation of G0 to G1 transition [GO:0070318]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; protein heterotetramerization [GO:0051290]; pyrimidine nucleobase metabolic process [GO:0006206]; response to ionizing radiation [GO:0010212]; retina development in camera-type eye [GO:0060041]; ribonucleoside diphosphate metabolic process [GO:0009185] | cell projection [GO:0042995]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nuclear envelope [GO:0005635]; ribonucleoside-diphosphate reductase complex [GO:0005971] | ATP binding [GO:0005524]; disordered domain specific binding [GO:0097718]; identical protein binding [GO:0042802]; ribonucleoside-diphosphate reductase activity [GO:0061731]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748] | 9612.60224447882 | -0.129410052375506 | 0.855520559925309 | 1 |
| P31350 | P31350 | RIR2_HUMAN | Ribonucleoside-diphosphate reductase subunit M2 (EC 1.17.4.1) (Ribonucleotide reductase small chain) (Ribonucleotide reductase small subunit) | RRM2 | 2'-deoxyribonucleotide biosynthetic process [GO:0009265]; blastocyst development [GO:0001824]; deoxyribonucleotide biosynthetic process [GO:0009263]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; protein heterotetramerization [GO:0051290]; ribonucleoside diphosphate metabolic process [GO:0009185] | cytosol [GO:0005829]; nucleus [GO:0005634]; ribonucleoside-diphosphate reductase complex [GO:0005971] | ferric iron binding [GO:0008199]; protein homodimerization activity [GO:0042803]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748] | 8105.426960577555 | 0.0996411743597147 | 0.90286627705601 | 1 |
| P56182 | P56182 | RRP1_HUMAN | Ribosomal RNA processing protein 1 homolog A (Novel nuclear protein 1) (NNP-1) (Nucleolar protein Nop52) (RRP1-like protein) | RRP1 | rRNA processing [GO:0006364] | chromosome [GO:0005694]; nucleolus [GO:0005730]; nucleus [GO:0005634]; preribosome, small subunit precursor [GO:0030688] | RNA binding [GO:0003723] | 13679.941836188249 | -0.0573483290771622 | 0.986496029078651 | 1 |
| Q9Y3B9 | Q9Y3B9 | RRP15_HUMAN | RRP15-like protein (Ribosomal RNA-processing protein 15) | RRP15 | maturation of 5.8S rRNA [GO:0000460]; maturation of LSU-rRNA [GO:0000470] | preribosome, large subunit precursor [GO:0030687] | 22460.7430007788 | 0.00882875134891278 | 0.841937904140679 | 1 | |
| O43818 | O43818 | U3IP2_HUMAN | U3 small nucleolar RNA-interacting protein 2 (RRP9 homolog) (U3 small nucleolar ribonucleoprotein-associated 55 kDa protein) (U3 snoRNP-associated 55 kDa protein) (U3-55K) | RRP9 | ribosomal small subunit biogenesis [GO:0042274]; rRNA processing [GO:0006364] | box C/D RNP complex [GO:0031428]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; small-subunit processome [GO:0032040] | RNA binding [GO:0003723]; snoRNA binding [GO:0030515]; U3 snoRNA binding [GO:0034511] | 17655.8294843666 | 0.0583302154401866 | 0.99717371396952 | 1 |
| Q96T23 | Q96T23 | RSF1_HUMAN | Remodeling and spacing factor 1 (Rsf-1) (HBV pX-associated protein 8) (Hepatitis B virus X-associated protein) (p325 subunit of RSF chromatin-remodeling complex) | RSF1 | chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; DNA-templated transcription initiation [GO:0006352]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-templated transcription [GO:0045892]; nucleosome assembly [GO:0006334]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of viral transcription [GO:0050434]; regulation of DNA-templated transcription [GO:0006355] | nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RSF complex [GO:0031213] | histone binding [GO:0042393]; histone octamer slider activity [GO:0140751]; metal ion binding [GO:0046872] | 5388.96337145472 | 0.0165471251550036 | 0.999976771005187 | 1 |
| O76021 | O76021 | RL1D1_HUMAN | Ribosomal L1 domain-containing protein 1 (CATX-11) (Cellular senescence-inhibited gene protein) (Protein PBK1) | RSL1D1 | maturation of LSU-rRNA [GO:0000470]; osteoblast differentiation [GO:0001649]; regulation of apoptotic process [GO:0042981]; regulation of cellular senescence [GO:2000772]; regulation of protein localization [GO:0032880] | 90S preribosome [GO:0030686]; chromosome [GO:0005694]; cytosolic large ribosomal subunit [GO:0022625]; membrane [GO:0016020]; nucleolus [GO:0005730] | cadherin binding [GO:0045296]; mRNA 3'-UTR binding [GO:0003730]; mRNA 5'-UTR binding [GO:0048027]; RNA binding [GO:0003723] | 42458.54739342535 | 0.0469072261999354 | 0.838687753390731 | 1 |
| Q15404 | Q15404 | RSU1_HUMAN | Ras suppressor protein 1 (RSP-1) (Rsu-1) | RSU1 | positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of GTPase activity [GO:0043547]; signal transduction [GO:0007165] | cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925] | 74777.15722814655 | 0.070610105437245 | 0.989181462744567 | 1 | |
| Q01196 | Q01196 | RUNX1_HUMAN | Runt-related transcription factor 1 (Acute myeloid leukemia 1 protein) (Core-binding factor subunit alpha-2) (CBF-alpha-2) (Oncogene AML-1) (Polyomavirus enhancer-binding protein 2 alpha B subunit) (PEA2-alpha B) (PEBP2-alpha B) (SL3-3 enhancer factor 1 alpha B subunit) (SL3/AKV core-binding factor alpha B subunit) | RUNX1 | cardiac muscle tissue regeneration [GO:0061026]; chondrocyte differentiation [GO:0002062]; hematopoietic stem cell proliferation [GO:0071425]; hemopoiesis [GO:0030097]; myeloid cell differentiation [GO:0030099]; myeloid leukocyte differentiation [GO:0002573]; negative regulation of CD4-positive, alpha-beta T cell differentiation [GO:0043371]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron differentiation [GO:0030182]; ossification [GO:0001503]; peripheral nervous system neuron development [GO:0048935]; positive regulation of angiogenesis [GO:0045766]; positive regulation of CD8-positive, alpha-beta T cell differentiation [GO:0043378]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of extracellular matrix organization [GO:1903055]; positive regulation of granulocyte differentiation [GO:0030854]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cardiac muscle cell proliferation [GO:0060043]; regulation of cell differentiation [GO:0045595]; regulation of connective tissue replacement [GO:1905203]; regulation of plasminogen activation [GO:0010755]; regulation of transcription by RNA polymerase II [GO:0006357] | chromatin [GO:0000785]; core-binding factor complex [GO:0016513]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] | ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription factor binding [GO:0140297]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]; transcription cis-regulatory region binding [GO:0000976]; transcription coactivator binding [GO:0001223]; transcription corepressor binding [GO:0001222] | 10829.73580161995 | 0.202921889808652 | 0.811582962998089 | 1 |
| P57060 | P57060 | RWD2B_HUMAN | RWD domain-containing protein 2B | RWDD2B | 2909.81091513899 | 0.130594152807679 | 0.839275135921099 | 1 | |||
| Q99584 | Q99584 | S10AD_HUMAN | Protein S100-A13 (S100 calcium-binding protein A13) | S100A13 | mast cell degranulation [GO:0043303]; positive regulation of canonical NF-kappaB signal transduction [GO:0043123]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokine production [GO:0001819]; positive regulation of interleukin-1 alpha production [GO:0032730]; protein transport [GO:0015031] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886] | calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; copper ion binding [GO:0005507]; fibroblast growth factor binding [GO:0017134]; lipid binding [GO:0008289]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270] | 49924.480006113445 | -0.152173938584739 | 0.811998082309964 | 1 |
| P06703 | P06703 | S10A6_HUMAN | Protein S100-A6 (Calcyclin) (Growth factor-inducible protein 2A9) (MLN 4) (Prolactin receptor-associated protein) (PRA) (S100 calcium-binding protein A6) | S100A6 | axonogenesis [GO:0007409]; positive regulation of fibroblast proliferation [GO:0048146]; signal transduction [GO:0007165] | collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; nuclear envelope [GO:0005635]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ruffle [GO:0001726] | calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; monoatomic ion transmembrane transporter activity [GO:0015075]; protein homodimerization activity [GO:0042803]; S100 protein binding [GO:0044548]; tropomyosin binding [GO:0005523]; zinc ion binding [GO:0008270] | 21972.61299504625 | 0.141576021366437 | 0.792152593954245 | 1 |
| Q9NTJ5 | Q9NTJ5 | SAC1_HUMAN | Phosphatidylinositol-3-phosphatase SAC1 (EC 3.1.3.64) (Phosphatidylinositol-4-phosphate phosphatase) (Suppressor of actin mutations 1-like protein) | SACM1L | phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856] | endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-plasma membrane contact site [GO:0140268]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139] | phosphatase activity [GO:0016791]; phosphatidylinositol phosphate 4-phosphatase activity [GO:0034596]; phosphatidylinositol-3-phosphate phosphatase activity [GO:0004438]; phosphatidylinositol-4-phosphate phosphatase activity [GO:0043812] | 23034.91353511105 | -0.0802806179057989 | 0.994293996018273 | 1 |
| Q15424 | Q15424 | SAFB1_HUMAN | Scaffold attachment factor B1 (SAF-B) (SAF-B1) (HSP27 estrogen response element-TATA box-binding protein) (HSP27 ERE-TATA-binding protein) | SAFB | chromatin organization [GO:0006325]; intracellular estrogen receptor signaling pathway [GO:0030520]; regulation of mRNA processing [GO:0050684]; regulation of transcription by RNA polymerase II [GO:0006357] | midbody [GO:0030496]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] | chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; RNA binding [GO:0003723]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565] | 14760.3092460016 | -0.0883293559353217 | 0.998417046492931 | 1 |
| Q14151 | Q14151 | SAFB2_HUMAN | Scaffold attachment factor B2 (SAF-B2) | SAFB2 | regulation of androgen receptor signaling pathway [GO:0060765]; regulation of mRNA processing [GO:0050684]; regulation of transcription by RNA polymerase II [GO:0006357]; Sertoli cell differentiation [GO:0060008] | cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; intracellular membrane-bounded organelle [GO:0043231]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] | identical protein binding [GO:0042802]; RNA binding [GO:0003723]; sequence-specific DNA binding [GO:0043565] | 17791.5856629217 | 0.00894944827908139 | 0.999780077148632 | 1 |
| Q9UPU9 | Q9UPU9 | SMAG1_HUMAN | Protein Smaug homolog 1 (Smaug 1) (hSmaug1) (Sterile alpha motif domain-containing protein 4A) (SAM domain-containing protein 4A) | SAMD4A | nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; positive regulation of translation [GO:0045727] | cell junction [GO:0030054]; cytosol [GO:0005829]; dendrite [GO:0030425]; fibrillar center [GO:0001650]; P-body [GO:0000932]; synapse [GO:0045202] | mRNA binding [GO:0003729]; RNA binding [GO:0003723]; translation repressor activity [GO:0030371] | 7799.875656183625 | -0.0388982964096447 | 0.990201141588916 | 1 |
| Q5K651 | Q5K651 | SAMD9_HUMAN | Sterile alpha motif domain-containing protein 9 (SAM domain-containing protein 9) | SAMD9 | endosomal vesicle fusion [GO:0034058]; innate immune response [GO:0045087] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231] | 3077.986579149325 | 0.0163143244083631 | 0.99999947819053 | 1 | |
| Q9Y512 | Q9Y512 | SAM50_HUMAN | Sorting and assembly machinery component 50 homolog (Transformation-related gene 3 protein) (TRG-3) | SAMM50 | cristae formation [GO:0042407]; inner mitochondrial membrane organization [GO:0007007]; mitochondrial respiratory chain complex assembly [GO:0033108]; protein insertion into mitochondrial outer membrane [GO:0045040] | extracellular exosome [GO:0070062]; membrane [GO:0016020]; MIB complex [GO:0140275]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; SAM complex [GO:0001401] | 18024.1003661205 | 0.0339721541400277 | 0.997875624170151 | 1 | |
| O00422 | O00422 | SAP18_HUMAN | Histone deacetylase complex subunit SAP18 (18 kDa Sin3-associated polypeptide) (2HOR0202) (Cell growth-inhibiting gene 38 protein) (Sin3-associated polypeptide p18) | SAP18 | mRNA processing [GO:0006397]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; positive regulation of apoptotic process [GO:0043065]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of transcription by RNA polymerase II [GO:0006357]; RNA splicing [GO:0008380] | ASAP complex [GO:0061574]; cytosol [GO:0005829]; histone deacetylase complex [GO:0000118]; nuclear body [GO:0016604]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] | RNA binding [GO:0003723]; transcription corepressor activity [GO:0003714] | 9777.13419639408 | -0.0526320339365609 | 0.998115178532911 | 1 |
| Q9UHR5 | Q9UHR5 | S30BP_HUMAN | SAP30-binding protein (Transcriptional regulator protein HCNGP) | SAP30BP | modulation by host of symbiont transcription [GO:0052472]; regulation of DNA-templated transcription [GO:0006355]; response to virus [GO:0009615] | intermediate filament cytoskeleton [GO:0045111]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] | 9283.614098666545 | 0.05836319093852 | 0.87867793358583 | 1 | |
| O43290 | O43290 | SNUT1_HUMAN | U4/U6.U5 tri-snRNP-associated protein 1 (SNU66 homolog) (hSnu66) (Squamous cell carcinoma antigen recognized by T-cells 1) (SART-1) (hSART-1) (U4/U6.U5 tri-snRNP-associated 110 kDa protein) (allergen Hom s 1) | SART1 | maturation of 5S rRNA [GO:0000481]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of cytotoxic T cell differentiation [GO:0045585]; spliceosomal snRNP assembly [GO:0000387] | Cajal body [GO:0015030]; catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; U2-type precatalytic spliceosome [GO:0071005]; U4/U6 x U5 tri-snRNP complex [GO:0046540] | RNA binding [GO:0003723] | 13739.0325894856 | 0.0328839939668573 | 0.999481067733055 | 1 |
| Q9Y3A5 | Q9Y3A5 | SBDS_HUMAN | Ribosome maturation protein SBDS (Shwachman-Bodian-Diamond syndrome protein) | SBDS | bone marrow development [GO:0048539]; bone mineralization [GO:0030282]; cytosolic ribosome assembly [GO:0042256]; hematopoietic progenitor cell differentiation [GO:0002244]; inner cell mass cell proliferation [GO:0001833]; leukocyte chemotaxis [GO:0030595]; mitotic spindle organization [GO:0007052]; rRNA processing [GO:0006364] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spindle pole [GO:0000922] | microtubule binding [GO:0008017]; ribosome binding [GO:0043022]; RNA binding [GO:0003723]; rRNA binding [GO:0019843] | 74731.3808627367 | 0.0527122309955608 | 0.956514074432079 | 1 |
| O95248 | O95248 | MTMR5_HUMAN | Myotubularin-related protein 5 (Inactive phosphatidylinositol 3-phosphatase 5) (SET-binding factor 1) (Sbf1) | SBF1 | protein dephosphorylation [GO:0006470]; spermatid development [GO:0007286] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; nuclear body [GO:0016604]; perinuclear region of cytoplasm [GO:0048471] | guanyl-nucleotide exchange factor activity [GO:0005085]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138] | 4595.299160336365 | -0.174768649685289 | 0.785155873993417 | 1 |
| Q6UWP8 | Q6UWP8 | SBSN_HUMAN | Suprabasin | SBSN | extracellular exosome [GO:0070062] | 1270.41581134624 | -0.218124600765429 | 0.975955412712035 | 1 | ||
| Q9H7N4 | Q9H7N4 | SFR19_HUMAN | Splicing factor, arginine/serine-rich 19 (SR-related C-terminal domain-associated factor 1) (SR-related and CTD-associated factor 1) (SR-related-CTD-associated factor) (SCAF) (Serine arginine-rich pre-mRNA splicing factor SR-A1) (SR-A1) | SCAF1 | mRNA processing [GO:0006397]; RNA splicing [GO:0008380]; transcription by RNA polymerase II [GO:0006366] | nucleus [GO:0005634] | protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; RNA polymerase II C-terminal domain binding [GO:0099122] | 2905.7437637275852 | -0.692143279014385 | 0.736201413140007 | 1 |
| Q99590 | Q99590 | SCAFB_HUMAN | Protein SCAF11 (CTD-associated SR protein 11) (Renal carcinoma antigen NY-REN-40) (SC35-interacting protein 1) (SR-related and CTD-associated factor 11) (SRSF2-interacting protein) (Serine/arginine-rich splicing factor 2-interacting protein) (Splicing factor, arginine/serine-rich 2-interacting protein) (Splicing regulatory protein 129) (SRrp129) | SCAF11 | mRNA processing [GO:0006397]; RNA splicing [GO:0008380]; RNA splicing, via transesterification reactions [GO:0000375]; spliceosomal complex assembly [GO:0000245] | nuclear body [GO:0016604]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654] | metal ion binding [GO:0046872]; RNA binding [GO:0003723] | 6148.013123536281 | -0.138053660428793 | 0.820042867902773 | 1 |
| Q9UPN6 | Q9UPN6 | SCAF8_HUMAN | SR-related and CTD-associated factor 8 (CDC5L complex-associated protein 7) (RNA-binding motif protein 16) | SCAF8 | mRNA polyadenylation [GO:0006378]; negative regulation of termination of RNA polymerase II transcription, poly(A)-coupled [GO:2000805]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; termination of RNA polymerase II transcription [GO:0006369] | cytoplasm [GO:0005737]; mRNA cleavage factor complex [GO:0005849]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] | mRNA binding [GO:0003729]; RNA binding [GO:0003723]; RNA polymerase core enzyme binding [GO:0043175]; RNA polymerase II C-terminal domain phosphoserine binding [GO:1990269]; RNA polymerase II complex binding [GO:0000993] | 3982.1457017580797 | 0.0215185744607027 | 0.98812306721808 | 1 |
| Q8NBX0 | Q8NBX0 | SCPDL_HUMAN | Saccharopine dehydrogenase-like oxidoreductase (EC 1.-.-.-) | SCCPDH | glycolipid biosynthetic process [GO:0009247] | extracellular region [GO:0005576]; lipid droplet [GO:0005811]; membrane [GO:0016020]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093] | oxidoreductase activity [GO:0016491] | 9290.84019753406 | -0.0857886059524589 | 0.972437214835649 | 1 |
| Q86SK9 | Q86SK9 | SCD5_HUMAN | Stearoyl-CoA desaturase 5 (EC 1.14.19.1) (Acyl-CoA-desaturase 4) (HSCD5) (Stearoyl-CoA 9-desaturase) (Stearoyl-CoA desaturase 2) | SCD5 | unsaturated fatty acid biosynthetic process [GO:0006636] | endoplasmic reticulum membrane [GO:0005789] | iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; stearoyl-CoA 9-desaturase activity [GO:0004768] | 8121.864515588824 | 0.0563804423253717 | 0.995312654242976 | 1 |
| Q9UIL1 | Q9UIL1 | SCOC_HUMAN | Short coiled-coil protein | SCOC | positive regulation of macroautophagy [GO:0016239]; regulation of protein complex stability [GO:0061635] | cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; trans-Golgi network [GO:0005802] | 14481.0629963871 | -0.0329657440793426 | 0.993411997247571 | 1 | |
| Q12765 | Q12765 | SCRN1_HUMAN | Secernin-1 | SCRN1 | exocytosis [GO:0006887]; proteolysis [GO:0006508]; regulation of synaptic vesicle cycle [GO:0098693] | cytoplasm [GO:0005737]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; presynapse [GO:0098793] | cysteine-type exopeptidase activity [GO:0070004]; dipeptidase activity [GO:0016805] | 36097.5600524361 | -0.00277097519654599 | 0.999998664334446 | 1 |
| Q0VDG4 | Q0VDG4 | SCRN3_HUMAN | Secernin-3 | SCRN3 | proteolysis [GO:0006508] | cysteine-type exopeptidase activity [GO:0070004]; dipeptidase activity [GO:0016805] | 13591.8540982216 | 0.051494704838723 | 0.930866915161391 | 1 | |
| Q96KG9 | Q96KG9 | SCYL1_HUMAN | N-terminal kinase-like protein (Coated vesicle-associated kinase of 90 kDa) (SCY1-like protein 1) (Telomerase regulation-associated protein) (Telomerase transcriptional element-interacting factor) (Teratoma-associated tyrosine kinase) | SCYL1 | inflammatory response [GO:0006954]; neuron development [GO:0048666]; protein localization [GO:0008104]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; spinal cord motor neuron differentiation [GO:0021522]; tRNA export from nucleus [GO:0006409] | centrosome [GO:0005813]; cis-Golgi network [GO:0005801]; COPI vesicle coat [GO:0030126]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; nucleus [GO:0005634] | ATP binding [GO:0005524]; cadherin binding [GO:0045296]; DNA binding [GO:0003677]; protein tyrosine kinase activity [GO:0004713] | 13601.87970255625 | 0.119840570689435 | 0.66466418591623 | 1 |
| Q6P3W7 | Q6P3W7 | SCYL2_HUMAN | SCY1-like protein 2 (Coated vesicle-associated kinase of 104 kDa) | SCYL2 | brain development [GO:0007420]; clathrin-dependent endocytosis [GO:0072583]; endosome to lysosome transport [GO:0008333]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; pyramidal neuron development [GO:0021860]; receptor internalization [GO:0031623] | clathrin-coated vesicle [GO:0030136]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794] | ATP binding [GO:0005524]; protein kinase activity [GO:0004672]; signaling receptor binding [GO:0005102] | 7353.14776603588 | 0.0281961199359546 | 0.995580861273492 | 1 |
| Q9NVU7 | Q9NVU7 | SDA1_HUMAN | Protein SDA1 homolog (Nucleolar protein 130) (SDA1 domain-containing protein 1) (hSDA) | SDAD1 | protein transport [GO:0015031]; ribosomal large subunit biogenesis [GO:0042273]; ribosomal large subunit export from nucleus [GO:0000055] | nucleolus [GO:0005730]; nucleoplasm [GO:0005654] | 4847.550286604945 | 0.0300912039455255 | 0.926249153432009 | 1 | |
| P31040 | P31040 | SDHA_HUMAN | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial (EC 1.3.5.1) (Flavoprotein subunit of complex II) (Fp) | SDHA | anaerobic respiration [GO:0009061]; mitochondrial electron transport, succinate to ubiquinone [GO:0006121]; nervous system development [GO:0007399]; proton motive force-driven mitochondrial ATP synthesis [GO:0042776]; respiratory electron transport chain [GO:0022904]; succinate metabolic process [GO:0006105]; tricarboxylic acid cycle [GO:0006099] | mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]; mitochondrion [GO:0005739]; nucleolus [GO:0005730] | electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; succinate dehydrogenase (quinone) activity [GO:0008177] | 23009.723682973403 | 0.0251241210071583 | 0.999974004053222 | 1 |
| O15027 | O15027 | SC16A_HUMAN | Protein transport protein Sec16A (SEC16 homolog A) (p250) | SEC16A | autophagy [GO:0006914]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum organization [GO:0007029]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; Golgi to plasma membrane transport [GO:0006893]; protein exit from endoplasmic reticulum [GO:0032527]; protein localization to endoplasmic reticulum exit site [GO:0070973]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; regulation of COPII vesicle coating [GO:0003400]; response to endoplasmic reticulum stress [GO:0034976]; substantia nigra development [GO:0021762] | cytosol [GO:0005829]; endoplasmic reticulum exit site [GO:0070971]; endoplasmic reticulum membrane [GO:0005789]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi membrane [GO:0000139]; organelle membrane [GO:0031090]; perinuclear region of cytoplasm [GO:0048471] | 14412.71204627005 | -0.152776375802337 | 0.935787982325998 | 1 | |
| Q15436 | Q15436 | SC23A_HUMAN | Protein transport protein Sec23A (hSec23A) (SEC23-related protein A) | SEC23A | COPII-coated vesicle cargo loading [GO:0090110]; intracellular protein transport [GO:0006886]; protein localization to plasma membrane [GO:0072659] | COPII vesicle coat [GO:0030127]; cytosol [GO:0005829]; endoplasmic reticulum exit site [GO:0070971]; endoplasmic reticulum membrane [GO:0005789]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi membrane [GO:0000139]; perinuclear region of cytoplasm [GO:0048471] | GTPase activator activity [GO:0005096]; zinc ion binding [GO:0008270] | 45514.418630915345 | -0.00283742884790907 | 0.999999999999991 | 1 |
| Q9Y6Y8 | Q9Y6Y8 | S23IP_HUMAN | SEC23-interacting protein (p125) | SEC23IP | endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; intracellular protein transport [GO:0006886] | COPII-coated ER to Golgi transport vesicle [GO:0030134]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231] | metal ion binding [GO:0046872]; phospholipase activity [GO:0004620]; RNA binding [GO:0003723] | 25092.52181649415 | -0.145531535029769 | 0.707673248268394 | 1 |
| O95486 | O95486 | SC24A_HUMAN | Protein transport protein Sec24A (SEC24-related protein A) | SEC24A | cholesterol homeostasis [GO:0042632]; COPII-coated vesicle cargo loading [GO:0090110]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intracellular protein transport [GO:0006886]; positive regulation of protein secretion [GO:0050714]; regulation of cholesterol transport [GO:0032374] | COPII vesicle coat [GO:0030127]; cytosol [GO:0005829]; endoplasmic reticulum exit site [GO:0070971]; endoplasmic reticulum membrane [GO:0005789]; ER to Golgi transport vesicle membrane [GO:0012507] | SNARE binding [GO:0000149]; zinc ion binding [GO:0008270] | 16581.73476995225 | 0.0302115925844476 | 0.99934421659034 | 1 |
| P53992 | P53992 | SC24C_HUMAN | Protein transport protein Sec24C (SEC24-related protein C) | SEC24C | COPII-coated vesicle cargo loading [GO:0090110]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; in utero embryonic development [GO:0001701]; intracellular protein transport [GO:0006886] | COPII vesicle coat [GO:0030127]; cytosol [GO:0005829]; endoplasmic reticulum exit site [GO:0070971]; endoplasmic reticulum membrane [GO:0005789]; ER to Golgi transport vesicle membrane [GO:0012507] | SNARE binding [GO:0000149]; zinc ion binding [GO:0008270] | 16894.30065494035 | -0.069926267996773 | 0.959770675200397 | 1 |
| O94855 | O94855 | SC24D_HUMAN | Protein transport protein Sec24D (SEC24-related protein D) | SEC24D | COPII-coated vesicle cargo loading [GO:0090110]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; in utero embryonic development [GO:0001701]; intracellular protein transport [GO:0006886] | COPII vesicle coat [GO:0030127]; cytosol [GO:0005829]; endoplasmic reticulum exit site [GO:0070971]; endoplasmic reticulum membrane [GO:0005789]; ER to Golgi transport vesicle membrane [GO:0012507]; intracellular membrane-bounded organelle [GO:0043231] | SNARE binding [GO:0000149]; zinc ion binding [GO:0008270] | 25668.99029970175 | -0.117691474573837 | 0.945193538829976 | 1 |
| P60468 | P60468 | SC61B_HUMAN | Protein transport protein Sec61 subunit beta | SEC61B | ERAD pathway [GO:0036503]; post-translational protein targeting to membrane, translocation [GO:0031204]; retrograde protein transport, ER to cytosol [GO:0030970]; SRP-dependent cotranslational protein targeting to membrane, translocation [GO:0006616] | cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum quality control compartment [GO:0044322]; endoplasmic reticulum Sec complex [GO:0031205]; membrane [GO:0016020]; Sec61 translocon complex [GO:0005784] | epidermal growth factor binding [GO:0048408]; ribosome binding [GO:0043022]; RNA binding [GO:0003723] | 2262330.66410025 | 0.0377502966533274 | 0.938927058924785 | 1 |
| Q9UGP8 | Q9UGP8 | SEC63_HUMAN | Translocation protein SEC63 homolog (DnaJ homolog subfamily C member 23) | SEC63 | liver development [GO:0001889]; post-translational protein targeting to endoplasmic reticulum membrane [GO:0006620]; post-translational protein targeting to membrane, translocation [GO:0031204]; protein targeting to membrane [GO:0006612]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614] | endoplasmic reticulum [GO:0005783]; membrane [GO:0016020]; Sec62/Sec63 complex [GO:0031207] | protein transmembrane transporter activity [GO:0008320]; RNA binding [GO:0003723]; signaling receptor activity [GO:0038023] | 38032.404615975654 | -0.0168197382775873 | 0.999999989603224 | 1 |
| Q96EE3 | Q96EE3 | SEH1_HUMAN | Nucleoporin SEH1 (GATOR2 complex protein SEH1) (Nup107-160 subcomplex subunit SEH1) (SEC13-like protein) | SEH1L | attachment of mitotic spindle microtubules to kinetochore [GO:0051315]; cell division [GO:0051301]; cellular response to amino acid starvation [GO:0034198]; cellular response to nutrient levels [GO:0031669]; defense response to Gram-positive bacterium [GO:0050830]; mitotic metaphase chromosome alignment [GO:0007080]; mRNA transport [GO:0051028]; negative regulation of TORC1 signaling [GO:1904262]; nuclear pore organization [GO:0006999]; nucleocytoplasmic transport [GO:0006913]; positive regulation of TOR signaling [GO:0032008]; positive regulation of TORC1 signaling [GO:1904263]; protein transport [GO:0015031]; protein-containing complex localization [GO:0031503] | cytosol [GO:0005829]; GATOR2 complex [GO:0061700]; kinetochore [GO:0000776]; lysosomal membrane [GO:0005765]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nuclear pore outer ring [GO:0031080]; Seh1-associated complex [GO:0035859] | structural molecule activity [GO:0005198] | 13376.4147535675 | -0.035222158265005 | 0.935995884186295 | 1 |
| Q9UBV2 | Q9UBV2 | SE1L1_HUMAN | Protein sel-1 homolog 1 (Suppressor of lin-12-like protein 1) (Sel-1L) | SEL1L | ERAD pathway [GO:0036503]; Notch signaling pathway [GO:0007219]; protein secretion [GO:0009306]; protein stabilization [GO:0050821]; retrograde protein transport, ER to cytosol [GO:0030970]; triglyceride metabolic process [GO:0006641] | Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; Hrd1p ubiquitin ligase complex [GO:0000836]; Hrd1p ubiquitin ligase ERAD-L complex [GO:0000839] | 16693.4018092602 | 0.187801838347936 | 0.78947162983092 | 1 | |
| Q8WWX9 | Q8WWX9 | SELM_HUMAN | Selenoprotein M (SelM) | SELENOM | adipose tissue development [GO:0060612]; corticosterone secretion [GO:0035934]; hormone metabolic process [GO:0042445]; multicellular organism growth [GO:0035264]; response to selenium ion [GO:0010269] | endoplasmic reticulum lumen [GO:0005788]; Golgi apparatus [GO:0005794]; perinuclear region of cytoplasm [GO:0048471] | oxidoreductase activity [GO:0016491] | 91901.6969471177 | -0.12096862565776 | 0.710214154384764 | 1 |
| P62341 | P62341 | SELT_HUMAN | Thioredoxin reductase-like selenoprotein T (SelT) (EC 1.8.1.9) | SELENOT | cell redox homeostasis [GO:0045454]; cellular oxidant detoxification [GO:0098869]; glucose homeostasis [GO:0042593]; insulin secretion involved in cellular response to glucose stimulus [GO:0035773]; pancreas development [GO:0031016]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of growth hormone secretion [GO:0060124]; response to glucose [GO:0009749]; selenocysteine incorporation [GO:0001514] | endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789] | selenium binding [GO:0008430]; thioredoxin-disulfide reductase (NADP) activity [GO:0004791] | 27779.82263878915 | -0.0572998529778734 | 0.927024999998544 | 1 |
| Q99985 | Q99985 | SEM3C_HUMAN | Semaphorin-3C (Semaphorin-E) (Sema E) | SEMA3C | axon guidance [GO:0007411]; blood vessel remodeling [GO:0001974]; cardiac endothelial to mesenchymal transition [GO:0140074]; cardiac right ventricle morphogenesis [GO:0003215]; dichotomous subdivision of terminal units involved in salivary gland branching [GO:0060666]; immune response [GO:0006955]; limb bud formation [GO:0060174]; negative chemotaxis [GO:0050919]; negative regulation of axon extension involved in axon guidance [GO:0048843]; neural crest cell migration [GO:0001755]; neural tube development [GO:0021915]; outflow tract septum morphogenesis [GO:0003148]; positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis [GO:1905312]; positive regulation of cell migration [GO:0030335]; post-embryonic development [GO:0009791]; pulmonary myocardium development [GO:0003350]; response to xenobiotic stimulus [GO:0009410]; semaphorin-plexin signaling pathway [GO:0071526]; somitogenesis [GO:0001756] | extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; plasma membrane [GO:0005886] | chemorepellent activity [GO:0045499]; semaphorin receptor binding [GO:0030215] | 15355.647080433351 | 0.0733011240780712 | 0.999521003414697 | 1 |
| P49903 | P49903 | SPS1_HUMAN | Selenide, water dikinase 1 (EC 2.7.9.3) (Selenium donor protein 1) (Selenophosphate synthase 1) | SEPHS1 | phosphorylation [GO:0016310]; protein modification process [GO:0036211]; selenocysteine biosynthetic process [GO:0016260] | cytoplasm [GO:0005737]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886] | ATP binding [GO:0005524]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; selenide, water dikinase activity [GO:0004756] | 14237.161422215999 | 0.0124956907345626 | 0.999994022014267 | 1 |
| Q16181 | Q16181 | SEPT7_HUMAN | Septin-7 (CDC10 protein homolog) | SEPTIN7 | cell differentiation [GO:0030154]; cilium assembly [GO:0060271]; cytoskeleton-dependent cytokinesis [GO:0061640]; positive regulation of non-motile cilium assembly [GO:1902857]; regulation of embryonic cell shape [GO:0016476]; spermatogenesis [GO:0007283] | axoneme [GO:0005930]; cell division site [GO:0032153]; cleavage furrow [GO:0032154]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; kinetochore [GO:0000776]; microtubule cytoskeleton [GO:0015630]; midbody [GO:0030496]; non-motile cilium [GO:0097730]; nucleus [GO:0005634]; septin complex [GO:0031105]; septin ring [GO:0005940]; sperm annulus [GO:0097227]; spindle [GO:0005819]; stress fiber [GO:0001725] | cadherin binding [GO:0045296]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; identical protein binding [GO:0042802]; molecular adaptor activity [GO:0060090]; structural molecule activity [GO:0005198] | 65187.9546677617 | 0.0840562307264725 | 0.995226013726267 | 1 |
| P05121 | P05121 | PAI1_HUMAN | Plasminogen activator inhibitor 1 (PAI) (PAI-1) (Endothelial plasminogen activator inhibitor) (Serpin E1) | SERPINE1 | angiogenesis [GO:0001525]; cellular response to lipopolysaccharide [GO:0071222]; defense response to Gram-negative bacterium [GO:0050829]; dentinogenesis [GO:0097187]; fibrinolysis [GO:0042730]; negative regulation of blood coagulation [GO:0030195]; negative regulation of cell adhesion mediated by integrin [GO:0033629]; negative regulation of cell migration [GO:0030336]; negative regulation of endopeptidase activity [GO:0010951]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of plasminogen activation [GO:0010757]; negative regulation of smooth muscle cell migration [GO:0014912]; negative regulation of smooth muscle cell-matrix adhesion [GO:2000098]; negative regulation of vascular wound healing [GO:0061044]; negative regulation of wound healing [GO:0061045]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood coagulation [GO:0030194]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of leukotriene production involved in inflammatory response [GO:0035491]; positive regulation of monocyte chemotaxis [GO:0090026]; positive regulation of odontoblast differentiation [GO:1901331]; positive regulation of receptor-mediated endocytosis [GO:0048260]; regulation of signaling receptor activity [GO:0010469]; replicative senescence [GO:0090399] | collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; peptidase inhibitor complex [GO:1904090]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; serine protease inhibitor complex [GO:0097180] | protease binding [GO:0002020]; serine-type endopeptidase inhibitor activity [GO:0004867]; signaling receptor binding [GO:0005102] | 309375.946050298 | -0.0364538046424171 | 0.999999755738842 | 1 |
| P50454 | P50454 | SERPH_HUMAN | Serpin H1 (47 kDa heat shock protein) (Arsenic-transactivated protein 3) (AsTP3) (Cell proliferation-inducing gene 14 protein) (Collagen-binding protein) (Colligin) (Rheumatoid arthritis-related antigen RA-A47) | SERPINH1 | chondrocyte development involved in endochondral bone morphogenesis [GO:0003433]; collagen biosynthetic process [GO:0032964]; collagen fibril organization [GO:0030199]; protein maturation [GO:0051604]; response to unfolded protein [GO:0006986] | collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; extracellular space [GO:0005615]; membrane raft [GO:0045121] | collagen binding [GO:0005518]; RNA binding [GO:0003723]; serine-type endopeptidase inhibitor activity [GO:0004867]; unfolded protein binding [GO:0051082] | 485659.9344151395 | 0.0381840046124132 | 0.999998017838941 | 1 |
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| Q15149 | |||||||||
| Q99715 | |||||||||
| P02452 | |||||||||
| P02751 | |||||||||
| P98160 | |||||||||
| P08123 | |||||||||
| P02461 | |||||||||
| P07996 | |||||||||
| Q8WWI1 | |||||||||
| P05997 | |||||||||
| P20908 | |||||||||
| Q8WUJ3 | |||||||||
| P21333 | |||||||||
| O75369 | |||||||||
| Q15063 | |||||||||
| P02786 | |||||||||
| Q12884 | |||||||||
| P12814 | |||||||||
| Q9UDY2 | |||||||||
| Q14195 | |||||||||
| Q02952 | |||||||||
| Q9NZM1 | |||||||||
| P35579 | |||||||||
| P35354 | |||||||||
| P47895 | |||||||||
| Q09666 | |||||||||
| P11717 | |||||||||
| Q14112 | |||||||||
| Q13620 | |||||||||
| P43490 | |||||||||
| Q3SY69 | |||||||||
| P17812 | |||||||||
| P21980 | |||||||||
| Q16647 | |||||||||
| P01024 | |||||||||
| Q5SW79 | |||||||||
| P06396 | |||||||||
| P12111 | |||||||||
| P35221 | |||||||||
| P12429 | |||||||||
| P78559 | |||||||||
| Q76M96 | |||||||||
| Q16881 | |||||||||
| P07093 | |||||||||
| P27487 | |||||||||
| P15144 | |||||||||
| Q9H5V8 | |||||||||
| P08729 | |||||||||
| Q04828 | |||||||||
| O94925 | |||||||||
| P08473 | |||||||||
| Q8IVL5 | |||||||||
| P35442 | |||||||||
| O60716 | |||||||||
| P08253 | |||||||||
| Q16822 | |||||||||
| Q9UJ72 | |||||||||
| Q9Y617 | |||||||||
| Q8WX93 | |||||||||
| Q32MZ4 | |||||||||
| Q6P179 | |||||||||
| P48681 | |||||||||
| O95340 | |||||||||
| P21580 | |||||||||
| Q00341 | |||||||||
| P49748 | |||||||||
| O43854 | |||||||||
| P07942 | |||||||||
| Q96KC8 | |||||||||
| Q96PD2 | |||||||||
| Q13418 | |||||||||
| Q7Z7G0 | |||||||||
| Q04446 | |||||||||
| P19022 | |||||||||
| O00469 | |||||||||
| Q8WUF5 | |||||||||
| Q14767 | |||||||||
| Q13308 | |||||||||
| P46940 | |||||||||
| Q9NZ08 | |||||||||
| O60488 | |||||||||
| P35222 | |||||||||
| Q9H4M9 | |||||||||
| Q9NZU5 | |||||||||
| Q15113 | |||||||||
| O94808 | |||||||||
| Q9UI42 | |||||||||
| Q15417 | |||||||||
| Q15582 | |||||||||
| P35908 | |||||||||
| P00750 | |||||||||
| Q9UHD8 | |||||||||
| P11047 | |||||||||
| Q8N6G6 | |||||||||
| Q05682 | |||||||||
| P17342 | |||||||||
| Q16363 | |||||||||
| Q9NR12 | |||||||||
| P05362 | |||||||||
| P00966 | |||||||||
| P05120 | |||||||||
| P15121 | |||||||||
| P04179 | |||||||||
| Q15785 | |||||||||
| O60271 | |||||||||
| Q9Y6N5 | |||||||||
| Q9P0V9 | |||||||||
| Q8IVF2 | |||||||||
| P01584 | |||||||||
| Q96AQ6 | |||||||||
| P54289 | |||||||||
| P13667 | |||||||||
| Q96HE7 | |||||||||
| P21810 | |||||||||
| Q16790 | |||||||||
| P23396 | |||||||||
| P01130 | |||||||||
| P51812 | |||||||||
| O95490 | |||||||||
| Q16222 | |||||||||
| Q7Z4N8 | |||||||||
| P08133 | |||||||||
| Q08431 | |||||||||
| P23142 | |||||||||
| Q01581 | |||||||||
| P10915 | |||||||||
| O75976 | |||||||||
| P23219 | |||||||||
| Q8IXK2 | |||||||||
| Q07954 | |||||||||
| P50225 | |||||||||
| P11413 | |||||||||
| Q5SSJ5 | |||||||||
| Q6PCE3 | |||||||||
| P05091 | |||||||||
| P49419 | |||||||||
| P41252 | |||||||||
| P50281 | |||||||||
| Q13618 | |||||||||
| Q00653 | |||||||||
| Q9BZG1 | |||||||||
| P11142 | |||||||||
| P63010 | |||||||||
| Q9UBG0 | |||||||||
| Q5GLZ8 | |||||||||
| P21266 | |||||||||
| Q9BS40 | |||||||||
| P35232 | |||||||||
| Q86VP6 | |||||||||
| P09601 | |||||||||
| Q8N8S7 | |||||||||
| Q16851 | |||||||||
| P28845 | |||||||||
| P26640 | |||||||||
| Q92626 | |||||||||
| P07686 | |||||||||
| P01583 | |||||||||
| Q96HH9 | |||||||||
| P48506 | |||||||||
| P47712 | |||||||||
| Q14314 | |||||||||
| Q53FA7 | |||||||||
| Q9H425 | |||||||||
| Q14204 | |||||||||
| P01033 | |||||||||
| Q92616 | |||||||||
| Q16666 | |||||||||
| Q99623 | |||||||||
| P23381 | |||||||||
| Q8N6Y2 | |||||||||
| P98155 | |||||||||
| P46977 | |||||||||
| Q86SQ0 | |||||||||
| Q70E73 | |||||||||
| Q6VY07 | |||||||||
| P41250 | |||||||||
| P56945 | |||||||||
| P29279 | |||||||||
| Q96C19 | |||||||||
| Q9UPN3 | |||||||||
| P26022 | |||||||||
| P00492 | |||||||||
| Q9BXS4 | |||||||||
| P50452 | |||||||||
| P05783 | |||||||||
| Q14980 | |||||||||
| Q9UBX5 | |||||||||
| O75094 | |||||||||
| Q06323 | |||||||||
| O14672 | |||||||||
| O00339 | |||||||||
| P52209 | |||||||||
| Q00325 | |||||||||
| P30044 | |||||||||
| P30740 | |||||||||
| P46734 | |||||||||
| P48307 | |||||||||
| P08648 | |||||||||
| O43175 | |||||||||
| O00116 |
