Selected Cell
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stat_data__min_2_Peptides
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| Q8TAE8 | Q8TAE8 | G45IP_HUMAN | Large ribosomal subunit protein mL64 (39S ribosomal protein L59, mitochondrial) (MRP-L59) (CKII beta-associating protein) (CR6-interacting factor 1) (CRIF1) (Growth arrest and DNA damage-inducible proteins-interacting protein 1) (Papillomavirus L2-interacting nuclear protein 1) (PLINP) (PLINP-1) (p53-responsive gene 6 protein) | GADD45GIP1 | cell cycle [GO:0007049]; mitochondrial translation [GO:0032543] | mitochondrial inner membrane [GO:0005743]; mitochondrial large ribosomal subunit [GO:0005762]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654] | 9049.80664764057 | 0.276044074141221 | 0.733013919439079 | 1 | |
| O14976 | O14976 | GAK_HUMAN | Cyclin-G-associated kinase (EC 2.7.11.1) (DnaJ homolog subfamily C member 26) | GAK | cell cycle [GO:0007049]; chaperone cofactor-dependent protein refolding [GO:0051085]; clathrin coat assembly [GO:0048268]; clathrin coat disassembly [GO:0072318]; clathrin-dependent endocytosis [GO:0072583]; endoplasmic reticulum organization [GO:0007029]; Golgi organization [GO:0007030]; Golgi to lysosome transport [GO:0090160]; intracellular transport [GO:0046907]; negative regulation of neuron projection development [GO:0010977]; phosphorylation [GO:0016310]; protein localization to Golgi apparatus [GO:0034067]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis [GO:0006898]; regulation of clathrin coat assembly [GO:1905443]; synaptic vesicle uncoating [GO:0016191] | clathrin-coated vesicle [GO:0030136]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; presynapse [GO:0098793]; vesicle [GO:0031982] | ATP binding [GO:0005524]; clathrin binding [GO:0030276]; cyclin binding [GO:0030332]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; protein-folding chaperone binding [GO:0051087] | 8048.586875110315 | -0.0647586902250477 | 0.996783661768467 | 1 |
| P54803 | P54803 | GALC_HUMAN | Galactocerebrosidase (GALCERase) (EC 3.2.1.46) (Galactocerebroside beta-galactosidase) (Galactosylceramidase) (Galactosylceramide beta-galactosidase) | GALC | galactosylceramide catabolic process [GO:0006683]; glycosphingolipid catabolic process [GO:0046479]; myelination [GO:0042552] | lysosomal lumen [GO:0043202]; lysosome [GO:0005764] | galactosylceramidase activity [GO:0004336] | 9586.16221891279 | -0.140726851444691 | 0.885790045334186 | 1 |
| P51570 | P51570 | GALK1_HUMAN | Galactokinase (EC 2.7.1.6) (Galactose kinase) | GALK1 | galactitol metabolic process [GO:0019402]; galactose catabolic process [GO:0019388]; galactose catabolic process via UDP-galactose [GO:0033499]; galactose metabolic process [GO:0006012]; glycolytic process from galactose [GO:0061623] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020] | ATP binding [GO:0005524]; galactokinase activity [GO:0004335]; galactose binding [GO:0005534]; L-arabinokinase activity [GO:0009702] | 23270.1211848093 | -0.100648966713085 | 0.875598769029237 | 1 |
| Q01415 | Q01415 | GALK2_HUMAN | N-acetylgalactosamine kinase (EC 2.7.1.157) (GalNAc kinase) (Galactokinase 2) | GALK2 | carbohydrate metabolic process [GO:0005975]; galactose metabolic process [GO:0006012] | cytosol [GO:0005829] | ATP binding [GO:0005524]; galactokinase activity [GO:0004335]; N-acetylgalactosamine kinase activity [GO:0033858] | 5379.900801055145 | 0.0235747129705001 | 0.942591382506338 | 1 |
| Q96C23 | Q96C23 | GALM_HUMAN | Galactose mutarotase (EC 5.1.3.3) (Aldose 1-epimerase) | GALM | carbohydrate metabolic process [GO:0005975]; galactose catabolic process via UDP-galactose [GO:0033499]; galactose metabolic process [GO:0006012]; glucose metabolic process [GO:0006006] | cytoplasm [GO:0005737]; extracellular exosome [GO:0070062] | aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246] | 15591.9442498342 | 0.109727103397614 | 0.763505295731367 | 1 |
| Q86SF2 | Q86SF2 | GALT7_HUMAN | N-acetylgalactosaminyltransferase 7 (EC 2.4.1.41) (Polypeptide GalNAc transferase 7) (GalNAc-T7) (pp-GaNTase 7) (Protein-UDP acetylgalactosaminyltransferase 7) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 7) | GALNT7 | carbohydrate metabolic process [GO:0005975]; O-glycan processing [GO:0016266]; protein O-linked glycosylation [GO:0006493] | extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; membrane [GO:0016020] | carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; polypeptide N-acetylgalactosaminyltransferase activity [GO:0004653] | 10409.980424828 | 0.0417369826490325 | 0.9488226281775 | 1 |
| P07902 | P07902 | GALT_HUMAN | Galactose-1-phosphate uridylyltransferase (Gal-1-P uridylyltransferase) (EC 2.7.7.12) (UDP-glucose--hexose-1-phosphate uridylyltransferase) | GALT | galactose catabolic process [GO:0019388]; galactose catabolic process via UDP-galactose [GO:0033499]; galactose metabolic process [GO:0006012]; UDP-glucose metabolic process [GO:0006011] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794] | UDP-glucose:hexose-1-phosphate uridylyltransferase activity [GO:0008108]; zinc ion binding [GO:0008270] | 9399.721879842746 | 0.0485142207264924 | 0.767260731653222 | 1 |
| Q14697 | Q14697 | GANAB_HUMAN | Neutral alpha-glucosidase AB (EC 3.2.1.207) (Alpha-glucosidase 2) (Glucosidase II subunit alpha) | GANAB | carbohydrate metabolic process [GO:0005975]; N-glycan processing [GO:0006491] | endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; glucosidase II complex [GO:0017177]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; melanosome [GO:0042470]; membrane [GO:0016020] | alpha-glucosidase activity [GO:0090599]; carbohydrate binding [GO:0030246]; glucan 1,3-alpha-glucosidase activity [GO:0033919]; RNA binding [GO:0003723] | 262015.63523358753 | -0.0519755817597548 | 0.999968414052896 | 1 |
| Q9NY12 | Q9NY12 | GAR1_HUMAN | H/ACA ribonucleoprotein complex subunit 1 (Nucleolar protein family A member 1) (snoRNP protein GAR1) | GAR1 | snoRNA guided rRNA pseudouridine synthesis [GO:0000454]; telomere maintenance via telomerase [GO:0007004] | box H/ACA scaRNP complex [GO:0072589]; box H/ACA snoRNP complex [GO:0031429]; box H/ACA telomerase RNP complex [GO:0090661]; chromosome, telomeric region [GO:0000781]; fibrillar center [GO:0001650]; nucleoplasm [GO:0005654]; telomerase holoenzyme complex [GO:0005697] | box H/ACA snoRNA binding [GO:0034513]; RNA binding [GO:0003723]; telomerase RNA binding [GO:0070034] | 30358.787614806948 | -0.00206896880570664 | 0.999859483135733 | 1 |
| P22102 | P22102 | PUR2_HUMAN | Trifunctional purine biosynthetic protein adenosine-3 [Includes: Phosphoribosylamine--glycine ligase (EC 6.3.4.13) (Glycinamide ribonucleotide synthetase) (GARS) (Phosphoribosylglycinamide synthetase); Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) (AIR synthase) (AIRS) (Phosphoribosyl-aminoimidazole synthetase); Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) (5'-phosphoribosylglycinamide transformylase) (GAR transformylase) (GART)] | GART | 'de novo' AMP biosynthetic process [GO:0044208]; 'de novo' IMP biosynthetic process [GO:0006189]; 'de novo' XMP biosynthetic process [GO:0097294]; adenine biosynthetic process [GO:0046084]; brainstem development [GO:0003360]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; glycine metabolic process [GO:0006544]; GMP biosynthetic process [GO:0006177]; purine nucleotide biosynthetic process [GO:0006164]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; response to inorganic substance [GO:0010035]; response to organic substance [GO:0010033]; tetrahydrofolate biosynthetic process [GO:0046654] | cytosol [GO:0005829]; extracellular exosome [GO:0070062] | ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylamine-glycine ligase activity [GO:0004637]; phosphoribosylformylglycinamidine cyclo-ligase activity [GO:0004641]; phosphoribosylglycinamide formyltransferase activity [GO:0004644] | 36973.2229473997 | -0.0434049675835063 | 0.999999924098881 | 1 |
| Q92908 | Q92908 | GATA6_HUMAN | Transcription factor GATA-6 (GATA-binding factor 6) | GATA6 | animal organ formation [GO:0048645]; atrioventricular canal development [GO:0036302]; atrioventricular node development [GO:0003162]; cardiac muscle cell differentiation [GO:0055007]; cardiac muscle cell proliferation [GO:0060038]; cardiac muscle hypertrophy in response to stress [GO:0014898]; cardiac vascular smooth muscle cell differentiation [GO:0060947]; cell fate commitment [GO:0045165]; cellular response to BMP stimulus [GO:0071773]; cellular response to gonadotropin stimulus [GO:0071371]; cellular response to hypoxia [GO:0071456]; club cell differentiation [GO:0060486]; endodermal cell fate determination [GO:0007493]; epithelial cell differentiation [GO:0030855]; G1 to G0 transition involved in cell differentiation [GO:0070315]; gene expression [GO:0010467]; heart contraction [GO:0060047]; in utero embryonic development [GO:0001701]; intestinal epithelial cell differentiation [GO:0060575]; liver development [GO:0001889]; lung saccule development [GO:0060430]; male gonad development [GO:0008584]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of miRNA transcription [GO:1902894]; negative regulation of sebum secreting cell proliferation [GO:1904003]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta1 production [GO:0032911]; negative regulation of transforming growth factor beta2 production [GO:0032912]; odontogenesis of dentin-containing tooth [GO:0042475]; outflow tract septum morphogenesis [GO:0003148]; pancreatic A cell differentiation [GO:0003310]; phospholipid metabolic process [GO:0006644]; positive regulation of angiogenesis [GO:0045766]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cardiac muscle myoblast proliferation [GO:0110024]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transforming growth factor beta activation [GO:1901390]; regulation of antimicrobial humoral response [GO:0002759]; response to cAMP [GO:0051591]; response to estrogen [GO:0043627]; response to growth factor [GO:0070848]; response to retinoic acid [GO:0032526]; response to toxic substance [GO:0009636]; response to xenobiotic stimulus [GO:0009410]; sebaceous gland cell differentiation [GO:0001949]; sinoatrial node development [GO:0003163]; skin epidermis development [GO:0098773]; smooth muscle cell differentiation [GO:0051145]; stem cell differentiation [GO:0048863]; tube morphogenesis [GO:0035239]; type B pancreatic cell differentiation [GO:0003309]; type II pneumocyte differentiation [GO:0060510] | chromatin [GO:0000785]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription regulator complex [GO:0005667] | chromatin binding [GO:0003682]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription factor binding [GO:0140297]; NFAT protein binding [GO:0051525]; protein kinase binding [GO:0019901]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]; transcription cis-regulatory region binding [GO:0000976]; transcription coactivator binding [GO:0001223]; zinc ion binding [GO:0008270] | 12092.18613792385 | 0.152941015500507 | 0.816823472208276 | 1 |
| A0A0B4J2D5;P0DPI2 | A0A0B4J2D5 | GAL3B_HUMAN | Putative glutamine amidotransferase-like class 1 domain-containing protein 3B, mitochondrial (Keio novel protein-I) (KNP-I) (Protein GT335) (Protein HES1) | GATD3B | mitochondrion [GO:0005739] | 29803.56053558205 | -0.00967537980564973 | 0.999279970587334 | 1 | ||
| P04062 | P04062 | GBA1_HUMAN | Lysosomal acid glucosylceramidase (Lysosomal acid GCase) (EC 3.2.1.45) (Acid beta-glucosidase) (Alglucerase) (Beta-glucocerebrosidase) (Beta-GC) (Beta-glucosylceramidase 1) (Cholesterol glucosyltransferase) (SGTase) (EC 2.4.1.-) (Cholesteryl-beta-glucosidase) (EC 3.2.1.-) (D-glucosyl-N-acylsphingosine glucohydrolase) (Glucosylceramidase beta 1) (Imiglucerase) (Lysosomal cholesterol glycosyltransferase) (Lysosomal galactosylceramidase) (EC 3.2.1.46) (Lysosomal glycosylceramidase) | GBA1 | antigen processing and presentation [GO:0019882]; autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; brain morphogenesis [GO:0048854]; cell maturation [GO:0048469]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cerebellar Purkinje cell layer formation [GO:0021694]; cholesterol metabolic process [GO:0008203]; determination of adult lifespan [GO:0008340]; establishment of skin barrier [GO:0061436]; glucosylceramide catabolic process [GO:0006680]; hematopoietic stem cell proliferation [GO:0071425]; homeostasis of number of cells [GO:0048872]; lipid glycosylation [GO:0030259]; lipid storage [GO:0019915]; lymphocyte migration [GO:0072676]; lysosome organization [GO:0007040]; microglia differentiation [GO:0014004]; microglial cell proliferation [GO:0061518]; motor behavior [GO:0061744]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein-containing complex assembly [GO:0031333]; neuromuscular process [GO:0050905]; neuron apoptotic process [GO:0051402]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein-containing complex disassembly [GO:0043243]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; pyramidal neuron differentiation [GO:0021859]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; respiratory electron transport chain [GO:0022904]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; sphingosine biosynthetic process [GO:0046512]; T cell differentiation in thymus [GO:0033077]; termination of signal transduction [GO:0023021] | endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802] | galactosylceramidase activity [GO:0004336]; glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295] | 41251.273516688496 | 0.0331686984187955 | 0.99357165830877 | 1 |
| O75600 | O75600 | KBL_HUMAN | 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial (AKB ligase) (EC 2.3.1.29) (Aminoacetone synthase) (Glycine acetyltransferase) | GCAT | amino acid metabolic process [GO:0006520]; biosynthetic process [GO:0009058]; threonine catabolic process [GO:0006567] | mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] | glycine C-acetyltransferase activity [GO:0008890]; pyridoxal phosphate binding [GO:0030170] | 9589.37010426009 | -0.270916561541548 | 0.89905379257037 | 1 |
| Q96CN9 | Q96CN9 | GCC1_HUMAN | GRIP and coiled-coil domain-containing protein 1 (Golgi coiled-coil protein 1) | GCC1 | cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; Golgi trans cisterna [GO:0000138] | small GTPase binding [GO:0031267] | 7264.998219941845 | 0.0966421585565249 | 0.695940398963386 | 1 | |
| Q8IWJ2 | Q8IWJ2 | GCC2_HUMAN | GRIP and coiled-coil domain-containing protein 2 (185 kDa Golgi coiled-coil protein) (GCC185) (CLL-associated antigen KW-11) (CTCL tumor antigen se1-1) (Ran-binding protein 2-like 4) (RanBP2L4) (Renal carcinoma antigen NY-REN-53) | GCC2 | Golgi ribbon formation [GO:0090161]; late endosome to Golgi transport [GO:0034499]; microtubule anchoring [GO:0034453]; microtubule organizing center organization [GO:0031023]; protein localization to Golgi apparatus [GO:0034067]; protein targeting to lysosome [GO:0006622]; recycling endosome to Golgi transport [GO:0071955]; regulation of protein exit from endoplasmic reticulum [GO:0070861]; retrograde transport, endosome to Golgi [GO:0042147] | cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; trans-Golgi network [GO:0005802] | identical protein binding [GO:0042802]; small GTPase binding [GO:0031267] | 4987.848217900355 | -0.0740356531554188 | 0.999999621127318 | 1 |
| Q92947 | Q92947 | GCDH_HUMAN | Glutaryl-CoA dehydrogenase, mitochondrial (GCD) (EC 1.3.8.6) | GCDH | fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; fatty-acyl-CoA biosynthetic process [GO:0046949]; tryptophan metabolic process [GO:0006568] | mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739] | fatty-acyl-CoA binding [GO:0000062]; flavin adenine dinucleotide binding [GO:0050660]; glutaryl-CoA dehydrogenase activity [GO:0004361] | 8691.11732937854 | -0.154858285115429 | 0.909854504033432 | 1 |
| Q9NXN4 | Q9NXN4 | GDAP2_HUMAN | Ganglioside-induced differentiation-associated protein 2 | GDAP2 | response to retinoic acid [GO:0032526] | lysosomal membrane [GO:0005765] | 3541.792559665465 | 0.0254389615601417 | 0.995692625937343 | 1 | |
| Q99988 | Q99988 | GDF15_HUMAN | Growth/differentiation factor 15 (GDF-15) (Macrophage inhibitory cytokine 1) (MIC-1) (NSAID-activated gene 1 protein) (NAG-1) (NSAID-regulated gene 1 protein) (NRG-1) (Placental TGF-beta) (Placental bone morphogenetic protein) (Prostate differentiation factor) | GDF15 | cell-cell signaling [GO:0007267]; cellular response to chemical stress [GO:0062197]; GDF15-GFRAL signaling pathway [GO:0160144]; negative regulation of appetite [GO:0032099]; negative regulation of growth hormone receptor signaling pathway [GO:0060400]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of multicellular organism growth [GO:0040015]; negative regulation of SMAD protein signal transduction [GO:0060392]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; positive regulation of fatty acid oxidation [GO:0046321]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction [GO:0051897]; reduction of food intake in response to dietary excess [GO:0002023]; response to metformin [GO:1901558]; signal transduction [GO:0007165]; transforming growth factor beta receptor signaling pathway [GO:0007179] | cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634] | cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; hormone activity [GO:0005179]; protein homodimerization activity [GO:0042803] | 10594.9996530233 | 0.0830207984325215 | 0.928179467915911 | 1 |
| P31150 | P31150 | GDIA_HUMAN | Rab GDP dissociation inhibitor alpha (Rab GDI alpha) (Guanosine diphosphate dissociation inhibitor 1) (GDI-1) (Oligophrenin-2) (Protein XAP-4) | GDI1 | negative regulation of axonogenesis [GO:0050771]; negative regulation of protein targeting to membrane [GO:0090315]; positive regulation of axon extension [GO:0045773]; positive regulation of toll-like receptor signaling pathway [GO:0034123]; protein transport [GO:0015031]; Rab protein signal transduction [GO:0032482]; response to calcium ion [GO:0051592]; signal transduction [GO:0007165]; vesicle-mediated transport [GO:0016192] | axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; midbody [GO:0030496]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; presynaptic cytosol [GO:0099523]; protein-containing complex [GO:0032991] | GDP-dissociation inhibitor activity [GO:0005092]; GTPase activator activity [GO:0005096]; Rab GDP-dissociation inhibitor activity [GO:0005093]; small GTPase binding [GO:0031267] | 86996.97273221126 | -0.0554277187070499 | 0.889598323100699 | 1 |
| P50395 | P50395 | GDIB_HUMAN | Rab GDP dissociation inhibitor beta (Rab GDI beta) (Guanosine diphosphate dissociation inhibitor 2) (GDI-2) | GDI2 | negative regulation of cilium assembly [GO:1902018]; negative regulation of protein localization to cilium [GO:1903565]; protein transport [GO:0015031]; signal transduction [GO:0007165]; small GTPase-mediated signal transduction [GO:0007264]; vesicle-mediated transport [GO:0016192] | azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; secretory granule lumen [GO:0034774]; synapse [GO:0045202]; vesicle [GO:0031982] | GTPase activator activity [GO:0005096]; Rab GDP-dissociation inhibitor activity [GO:0005093]; RNA binding [GO:0003723]; small GTPase binding [GO:0031267] | 126611.277057447 | -0.0510395242651902 | 0.99819352131222 | 1 |
| O14893 | O14893 | GEMI2_HUMAN | Gem-associated protein 2 (Gemin-2) (Component of gems 2) (Survival of motor neuron protein-interacting protein 1) (SMN-interacting protein 1) | GEMIN2 | mRNA processing [GO:0006397]; negative regulation of RNA binding [GO:1905215]; RNA splicing [GO:0008380]; RNA splicing, via transesterification reactions [GO:0000375]; spliceosomal complex assembly [GO:0000245]; spliceosomal snRNP assembly [GO:0000387] | cytosol [GO:0005829]; Gemini of coiled bodies [GO:0097504]; nuclear body [GO:0016604]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; SMN complex [GO:0032797]; SMN-Sm protein complex [GO:0034719]; spliceosomal complex [GO:0005681] | 9403.193925847416 | 0.803926432928865 | 0.733676687019746 | 1 | |
| P57678 | P57678 | GEMI4_HUMAN | Gem-associated protein 4 (Gemin-4) (Component of gems 4) (p97) | GEMIN4 | rRNA processing [GO:0006364]; spliceosomal snRNP assembly [GO:0000387] | Cajal body [GO:0015030]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; Gemini of coiled bodies [GO:0097504]; membrane [GO:0016020]; nuclear body [GO:0016604]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; small nuclear ribonucleoprotein complex [GO:0030532]; SMN complex [GO:0032797]; SMN-Sm protein complex [GO:0034719] | ribonucleoprotein complex binding [GO:0043021] | 4616.88022012444 | -0.148968017652717 | 0.970460189552795 | 1 |
| O43681 | O43681 | GET3_HUMAN | ATPase GET3 (EC 3.6.-.-) (Arsenical pump-driving ATPase) (Arsenite-stimulated ATPase) (Guided entry of tail-anchored proteins factor 3, ATPase) (Transmembrane domain recognition complex 40 kDa ATPase subunit) (hARSA-I) (hASNA-I) | GET3 | post-translational protein targeting to endoplasmic reticulum membrane [GO:0006620]; protein insertion into ER membrane [GO:0045048]; tail-anchored membrane protein insertion into ER membrane [GO:0071816] | cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; GET complex [GO:0043529]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654] | arsenite transmembrane transporter activity [GO:0015105]; ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; membrane insertase activity [GO:0032977]; metal ion binding [GO:0046872] | 43961.00222677135 | 0.0466374404275564 | 0.888623038284781 | 1 |
| Q9UJY5 | Q9UJY5 | GGA1_HUMAN | ADP-ribosylation factor-binding protein GGA1 (Gamma-adaptin-related protein 1) (Golgi-localized, gamma ear-containing, ARF-binding protein 1) | GGA1 | Golgi to plasma membrane protein transport [GO:0043001]; Golgi to plasma membrane transport [GO:0006893]; intracellular protein transport [GO:0006886]; positive regulation of protein catabolic process [GO:0045732]; protein catabolic process [GO:0030163]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to ciliary membrane [GO:1903441]; retrograde transport, endosome to Golgi [GO:0042147] | cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; trans-Golgi network [GO:0005802] | phosphatidylinositol binding [GO:0035091]; small GTPase binding [GO:0031267]; ubiquitin binding [GO:0043130] | 7943.13690052005 | 0.150284482899471 | 0.789492462049391 | 1 |
| Q9UJY4 | Q9UJY4 | GGA2_HUMAN | ADP-ribosylation factor-binding protein GGA2 (Gamma-adaptin-related protein 2) (Golgi-localized, gamma ear-containing, ARF-binding protein 2) (VHS domain and ear domain of gamma-adaptin) (Vear) | GGA2 | Golgi to plasma membrane protein transport [GO:0043001]; Golgi to plasma membrane transport [GO:0006893]; intracellular protein transport [GO:0006886]; protein localization to cell surface [GO:0034394] | clathrin-coated vesicle [GO:0030136]; early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; trans-Golgi network [GO:0005802] | phosphatidylinositol binding [GO:0035091]; small GTPase binding [GO:0031267]; ubiquitin binding [GO:0043130] | 7616.34274556168 | -0.376801621782713 | 0.98994081684932 | 1 |
| Q9BVM4 | Q9BVM4 | GGACT_HUMAN | Gamma-glutamylaminecyclotransferase (GGACT) (EC 4.3.2.8) (AIG2-like domain-containing protein 1) (Gamma-glutamylamine cyclotransferase) | GGACT | cellular modified amino acid catabolic process [GO:0042219] | cytosol [GO:0005829]; extracellular exosome [GO:0070062] | gamma-glutamylaminecyclotransferase activity [GO:0061929] | 10473.2449907011 | 0.113245646860636 | 0.898756253054987 | 1 |
| O75223 | O75223 | GGCT_HUMAN | Gamma-glutamylcyclotransferase (EC 4.3.2.9) (Cytochrome c-releasing factor 21) | GGCT | release of cytochrome c from mitochondria [GO:0001836] | cytosol [GO:0005829]; extracellular exosome [GO:0070062] | gamma-glutamylcyclotransferase activity [GO:0003839]; protein homodimerization activity [GO:0042803] | 37789.59309357885 | 0.00338586954256167 | 0.999999995625052 | 1 |
| P38435 | P38435 | VKGC_HUMAN | Vitamin K-dependent gamma-carboxylase (EC 4.1.1.90) (Gamma-glutamyl carboxylase) (Peptidyl-glutamate 4-carboxylase) (Vitamin K gamma glutamyl carboxylase) | GGCX | blood coagulation [GO:0007596]; protein modification process [GO:0036211]; vitamin K metabolic process [GO:0042373] | endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020] | gamma-glutamyl carboxylase activity [GO:0008488]; vitamin binding [GO:0019842] | 16834.5556929051 | -0.0361463038538976 | 0.990919960994685 | 1 |
| Q92820 | Q92820 | GGH_HUMAN | Gamma-glutamyl hydrolase (EC 3.4.19.9) (Conjugase) (GH) (Gamma-Glu-X carboxypeptidase) | GGH | tetrahydrofolylpolyglutamate metabolic process [GO:0046900] | azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; melanosome [GO:0042470]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; vacuole [GO:0005773] | exopeptidase activity [GO:0008238]; gamma-glutamyl-peptidase activity [GO:0034722]; omega peptidase activity [GO:0008242] | 87222.14386699311 | -0.0159122659934849 | 0.999998162942352 | 1 |
| Q9UJ14 | Q9UJ14 | GGT7_HUMAN | Glutathione hydrolase 7 (EC 3.4.19.13) (Gamma-glutamyltransferase 7) (GGT 7) (EC 2.3.2.2) (Gamma-glutamyltransferase-like 3) (Gamma-glutamyltransferase-like 5) (Gamma-glutamyltranspeptidase 7) [Cleaved into: Glutathione hydrolase 7 heavy chain; Glutathione hydrolase 7 light chain] | GGT7 | glutathione biosynthetic process [GO:0006750]; glutathione catabolic process [GO:0006751]; leukotriene D4 biosynthetic process [GO:1901750]; negative regulation of response to oxidative stress [GO:1902883] | plasma membrane [GO:0005886] | glutathione hydrolase activity [GO:0036374]; leukotriene C4 gamma-glutamyl transferase activity [GO:0103068] | 4383.978303059384 | 0.031264538089661 | 0.999998846311849 | 1 |
| Q6Y7W6 | Q6Y7W6 | GGYF2_HUMAN | GRB10-interacting GYF protein 2 (PERQ amino acid-rich with GYF domain-containing protein 2) (Trinucleotide repeat-containing gene 15 protein) | GIGYF2 | adult locomotory behavior [GO:0008344]; feeding behavior [GO:0007631]; homeostasis of number of cells within a tissue [GO:0048873]; insulin-like growth factor receptor signaling pathway [GO:0048009]; mitotic G1 DNA damage checkpoint signaling [GO:0031571]; mRNA destabilization [GO:0061157]; multicellular organism growth [GO:0035264]; musculoskeletal movement [GO:0050881]; negative regulation of translation [GO:0017148]; negative regulation of translational initiation [GO:0045947]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; neuromuscular process controlling balance [GO:0050885]; post-embryonic development [GO:0009791]; post-transcriptional gene silencing [GO:0016441]; rescue of stalled ribosome [GO:0072344]; spinal cord motor neuron differentiation [GO:0021522] | cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endosome [GO:0005768]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; perikaryon [GO:0043204]; protein-containing complex [GO:0032991]; proximal dendrite [GO:1990635]; vesicle [GO:0031982] | cadherin binding [GO:0045296]; molecular adaptor activity [GO:0060090]; proline-rich region binding [GO:0070064]; RNA binding [GO:0003723] | 12528.24860047575 | 0.0782479018244333 | 0.669536280813388 | 1 |
| Q9NU53 | Q9NU53 | GINM1_HUMAN | Glycoprotein integral membrane protein 1 | GINM1 | membrane [GO:0016020] | 3195.9395368894902 | -0.0303457147360606 | 0.996413961438313 | 1 | ||
| P17302 | P17302 | CXA1_HUMAN | Gap junction alpha-1 protein (Connexin-43) (Cx43) (Gap junction 43 kDa heart protein) | GJA1 | adult heart development [GO:0007512]; atrial cardiac muscle cell action potential [GO:0086014]; atrial ventricular junction remodeling [GO:0003294]; blood vessel morphogenesis [GO:0048514]; bone development [GO:0060348]; bone remodeling [GO:0046849]; cardiac conduction system development [GO:0003161]; cell communication by chemical coupling [GO:0010643]; cell communication by electrical coupling [GO:0010644]; cell communication by electrical coupling involved in cardiac conduction [GO:0086064]; cell-cell signaling [GO:0007267]; cellular response to amyloid-beta [GO:1904646]; cellular response to pH [GO:0071467]; columnar/cuboidal epithelial cell maturation [GO:0002069]; embryonic digit morphogenesis [GO:0042733]; establishment of mitotic spindle orientation [GO:0000132]; export across plasma membrane [GO:0140115]; gap junction assembly [GO:0016264]; glutamate secretion [GO:0014047]; heart development [GO:0007507]; heart looping [GO:0001947]; in utero embryonic development [GO:0001701]; lens development in camera-type eye [GO:0002088]; maintenance of blood-brain barrier [GO:0035633]; male gonad development [GO:0008584]; microtubule-based transport [GO:0099111]; milk ejection reflex [GO:0060156]; monoatomic ion transmembrane transport [GO:0034220]; negative regulation of cell growth [GO:0030308]; negative regulation of gene expression [GO:0010629]; negative regulation of gonadotropin secretion [GO:0032277]; negative regulation of trophoblast cell migration [GO:1901164]; neuroblast migration [GO:0097402]; neuron migration [GO:0001764]; osteoblast differentiation [GO:0001649]; positive regulation of canonical NF-kappaB signal transduction [GO:0043123]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; positive regulation of mesodermal cell differentiation [GO:1905772]; positive regulation of morphogenesis of an epithelium [GO:1905332]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of striated muscle tissue development [GO:0045844]; positive regulation of vascular associated smooth muscle cell proliferation [GO:1904707]; protein localization [GO:0008104]; regulation of atrial cardiac muscle cell membrane depolarization [GO:0060371]; regulation of bone mineralization [GO:0030500]; regulation of bone remodeling [GO:0046850]; regulation of ventricular cardiac muscle cell membrane depolarization [GO:0060373]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307]; signal transduction [GO:0007165]; skeletal muscle tissue regeneration [GO:0043403]; spermatogenesis [GO:0007283]; T cell proliferation [GO:0042098]; xenobiotic transport [GO:0042908] | apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell-cell contact zone [GO:0044291]; connexin complex [GO:0005922]; contractile fiber [GO:0043292]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; fascia adherens [GO:0005916]; focal adhesion [GO:0005925]; gap junction [GO:0005921]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; Golgi-associated vesicle membrane [GO:0030660]; intercalated disc [GO:0014704]; intermediate filament [GO:0005882]; intracellular membrane-bounded organelle [GO:0043231]; lateral plasma membrane [GO:0016328]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; tight junction [GO:0070160] | alpha-tubulin binding [GO:0043014]; beta-catenin binding [GO:0008013]; beta-tubulin binding [GO:0048487]; efflux transmembrane transporter activity [GO:0015562]; gap junction channel activity [GO:0005243]; gap junction channel activity involved in cardiac conduction electrical coupling [GO:0086075]; gap junction channel activity involved in cell communication by electrical coupling [GO:1903763]; gap junction hemi-channel activity [GO:0055077]; glutathione transmembrane transporter activity [GO:0034634]; monoatomic ion transmembrane transporter activity [GO:0015075]; protein tyrosine kinase binding [GO:1990782]; scaffold protein binding [GO:0097110]; signaling receptor binding [GO:0005102]; tubulin binding [GO:0015631] | 115185.35885876551 | 0.022037101430465 | 0.994862941554442 | 1 |
| P06280 | P06280 | AGAL_HUMAN | Alpha-galactosidase A (EC 3.2.1.22) (Alpha-D-galactosidase A) (Alpha-D-galactoside galactohydrolase) (Galactosylgalactosylglucosylceramidase GLA) (Melibiase) (Agalsidase) | GLA | glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; oligosaccharide metabolic process [GO:0009311] | azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764] | alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102] | 11380.304132624999 | 0.0368028905493154 | 0.991141348179051 | 1 |
| Q92896 | Q92896 | GSLG1_HUMAN | Golgi apparatus protein 1 (CFR-1) (Cysteine-rich fibroblast growth factor receptor) (E-selectin ligand 1) (ESL-1) (Golgi sialoglycoprotein MG-160) | GLG1 | bone morphogenesis [GO:0060349]; negative regulation of protein processing [GO:0010955]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; protein processing [GO:0016485]; regulation of chondrocyte differentiation [GO:0032330]; transforming growth factor beta receptor signaling pathway [GO:0007179] | extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; membrane [GO:0016020]; microtubule organizing center [GO:0005815]; plasma membrane [GO:0005886] | fibroblast growth factor binding [GO:0017134]; signaling receptor binding [GO:0005102] | 37533.839133689704 | 0.0340851557202373 | 0.999999953603074 | 1 |
| P35754 | P35754 | GLRX1_HUMAN | Glutaredoxin-1 (Thioltransferase-1) (TTase-1) | GLRX | nucleobase-containing small molecule interconversion [GO:0015949]; positive regulation of membrane potential [GO:0045838] | cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]; nucleus [GO:0005634] | glutathione disulfide oxidoreductase activity [GO:0015038]; sodium channel regulator activity [GO:0017080] | 215528.6889585035 | -0.0861497383017886 | 0.913121642360624 | 1 |
| Q49A26 | Q49A26 | GLYR1_HUMAN | Cytokine-like nuclear factor N-PAC (NPAC) (3-hydroxyisobutyrate dehydrogenase-like protein) (Glyoxylate reductase 1 homolog) (Nuclear protein NP60) (Nuclear protein of 60 kDa) (Nucleosome-destabilizing factor) (hNDF) (Putative oxidoreductase GLYR1) | GLYR1 | transcription elongation-coupled chromatin remodeling [GO:0140673]; transcription initiation-coupled chromatin remodeling [GO:0045815] | chromatin [GO:0000785]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786] | chromatin binding [GO:0003682]; chromatin-protein adaptor activity [GO:0140463]; DNA binding [GO:0003677]; histone binding [GO:0042393]; methylated histone binding [GO:0035064]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; nucleosome binding [GO:0031491]; oxidoreductase activity [GO:0016491] | 4014.03306355209 | -0.342927975752042 | 0.837217497887991 | 1 |
| P17900 | P17900 | SAP3_HUMAN | Ganglioside GM2 activator (Cerebroside sulfate activator protein) (GM2-AP) (Sphingolipid activator protein 3) (SAP-3) [Cleaved into: Ganglioside GM2 activator isoform short] | GM2A | ganglioside catabolic process [GO:0006689]; glycosphingolipid catabolic process [GO:0046479]; learning or memory [GO:0007611]; lipid storage [GO:0019915]; lipid transport [GO:0006869]; maintenance of location in cell [GO:0051651]; neuromuscular process controlling balance [GO:0050885]; oligosaccharide catabolic process [GO:0009313] | apical plasma membrane [GO:0016324]; azurophil granule lumen [GO:0035578]; basolateral plasma membrane [GO:0016323]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202] | beta-N-acetylgalactosaminidase activity [GO:0032428]; lipid transporter activity [GO:0005319]; phospholipase activator activity [GO:0016004]; sphingolipid activator protein activity [GO:0030290] | 42871.23959567175 | 0.111283474591429 | 0.818515785474938 | 1 |
| P60983 | P60983 | GMFB_HUMAN | Glia maturation factor beta (GMF-beta) | GMFB | actin filament debranching [GO:0071846]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; nervous system development [GO:0007399]; protein phosphorylation [GO:0006468] | actin binding [GO:0003779]; Arp2/3 complex binding [GO:0071933]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; protein kinase inhibitor activity [GO:0004860] | 106771.445788791 | 0.0859930679564788 | 0.821908694207362 | 1 | |
| Q9Y5P6 | Q9Y5P6 | GMPPB_HUMAN | Mannose-1-phosphate guanyltransferase beta (EC 2.7.7.13) (GDP-mannose pyrophosphorylase B) (GTP-mannose-1-phosphate guanylyltransferase beta) | GMPPB | GDP-mannose biosynthetic process [GO:0009298]; protein glycosylation [GO:0006486] | cytoplasm [GO:0005737] | GTP binding [GO:0005525]; mannose-1-phosphate guanylyltransferase (GTP) activity [GO:0004475] | 26765.353598601 | -0.0284602140966752 | 0.991515031319501 | 1 |
| P49915 | P49915 | GUAA_HUMAN | GMP synthase [glutamine-hydrolyzing] (EC 6.3.5.2) (GMP synthetase) (Glutamine amidotransferase) | GMPS | glutamine metabolic process [GO:0006541]; GMP biosynthetic process [GO:0006177]; purine nucleobase biosynthetic process [GO:0009113]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168] | cytosol [GO:0005829] | ATP binding [GO:0005524]; GMP synthase (glutamine-hydrolyzing) activity [GO:0003922]; GMP synthase activity [GO:0003921] | 16141.411954913601 | -0.0432947866987727 | 0.999467240983839 | 1 |
| P29992 | P29992 | GNA11_HUMAN | Guanine nucleotide-binding protein subunit alpha-11 (G alpha-11) (G-protein subunit alpha-11) (Guanine nucleotide-binding protein G(y) subunit alpha) | GNA11 | action potential [GO:0001508]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; cellular response to pH [GO:0071467]; cranial skeletal system development [GO:1904888]; developmental pigmentation [GO:0048066]; endothelin receptor signaling pathway [GO:0086100]; entrainment of circadian clock [GO:0009649]; G protein-coupled acetylcholine receptor signaling pathway [GO:0007213]; heart development [GO:0007507]; ion channel modulating, G protein-coupled receptor signaling pathway [GO:0099105]; ligand-gated ion channel signaling pathway [GO:1990806]; phospholipase C-activating dopamine receptor signaling pathway [GO:0060158]; phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway [GO:0007207]; phototransduction, visible light [GO:0007603]; positive regulation of insulin secretion [GO:0032024]; regulation of blood pressure [GO:0008217]; regulation of melanocyte differentiation [GO:0045634]; signal transduction [GO:0007165]; skeletal system development [GO:0001501] | cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; heterotrimeric G-protein complex [GO:0005834]; lysosomal membrane [GO:0005765]; photoreceptor outer segment [GO:0001750]; plasma membrane [GO:0005886]; synapse [GO:0045202] | enzyme regulator activity [GO:0030234]; G protein activity [GO:0003925]; G protein-coupled receptor binding [GO:0001664]; G-protein beta/gamma-subunit complex binding [GO:0031683]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; metal ion binding [GO:0046872] | 54942.854456331595 | 0.00962329488026751 | 0.999997858944284 | 1 |
| P04899 | P04899 | GNAI2_HUMAN | Guanine nucleotide-binding protein G(i) subunit alpha-2 (Adenylate cyclase-inhibiting G alpha protein) | GNAI2 | adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell population proliferation [GO:0008283]; G protein-coupled acetylcholine receptor signaling pathway [GO:0007213]; G protein-coupled adenosine receptor signaling pathway [GO:0001973]; G protein-coupled receptor signaling pathway [GO:0007186]; gamma-aminobutyric acid signaling pathway [GO:0007214]; negative regulation of adenylate cyclase activity [GO:0007194]; negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process [GO:0140199]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of calcium ion-dependent exocytosis [GO:0045955]; negative regulation of synaptic transmission [GO:0050805]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of urine volume [GO:0035810]; positive regulation of vascular associated smooth muscle cell proliferation [GO:1904707]; regulation of calcium ion transport [GO:0051924]; response to nutrient [GO:0007584]; signal transduction [GO:0007165] | cell body [GO:0044297]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; extracellular vesicle [GO:1903561]; heterotrimeric G-protein complex [GO:0005834]; membrane [GO:0016020]; midbody [GO:0030496]; neuronal dense core vesicle [GO:0098992]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; synapse [GO:0045202] | G protein-coupled receptor binding [GO:0001664]; G-protein beta/gamma-subunit complex binding [GO:0031683]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; metal ion binding [GO:0046872] | 174869.26680654398 | -0.113219874428789 | 0.942862575676081 | 1 |
| P62879 | P62879 | GBB2_HUMAN | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 (G protein subunit beta-2) (Transducin beta chain 2) | GNB2 | G protein-coupled receptor signaling pathway [GO:0007186]; regulation of potassium ion transmembrane transport [GO:1901379] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; heterotrimeric G-protein complex [GO:0005834]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; vesicle [GO:0031982] | GTPase activity [GO:0003924]; GTPase binding [GO:0051020]; protein-containing complex binding [GO:0044877]; signaling receptor complex adaptor activity [GO:0030159] | 96475.06909120156 | 0.280560085585077 | 0.97454977447996 | 1 |
| Q9Y223 | Q9Y223 | GLCNE_HUMAN | Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase (UDP-GlcNAc-2-epimerase/ManAc kinase) [Includes: UDP-N-acetylglucosamine 2-epimerase (hydrolyzing) (EC 3.2.1.183) (UDP-GlcNAc-2-epimerase) (Uridine diphosphate-N-acetylglucosamine-2-epimerase); N-acetylmannosamine kinase (EC 2.7.1.60) (ManAc kinase)] | GNE | N-acetylglucosamine biosynthetic process [GO:0006045]; N-acetylneuraminate biosynthetic process [GO:0046380]; UDP-N-acetylglucosamine metabolic process [GO:0006047] | cytosol [GO:0005829] | ATP binding [GO:0005524]; hexokinase activity [GO:0004396]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; N-acylmannosamine kinase activity [GO:0009384]; UDP-N-acetylglucosamine 2-epimerase activity [GO:0008761] | 9406.590960806374 | -0.0467649671862694 | 0.815110989365065 | 1 |
| Q92805 | Q92805 | GOGA1_HUMAN | Golgin subfamily A member 1 (Golgin-97) | GOLGA1 | acrosomal vesicle [GO:0001669]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; perinuclear region of cytoplasm [GO:0048471]; trans-Golgi network [GO:0005802] | 10219.55062791735 | 0.110091769808388 | 0.87606806775129 | 1 | ||
| Q08378 | Q08378 | GOGA3_HUMAN | Golgin subfamily A member 3 (Golgi complex-associated protein of 170 kDa) (GCP170) (Golgin-160) | GOLGA3 | cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi membrane [GO:0000139]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654] | cadherin binding [GO:0045296] | 23705.50933190075 | -0.0516765630650332 | 0.999823156890712 | 1 | |
| Q7Z5G4 | Q7Z5G4 | GOGA7_HUMAN | Golgin subfamily A member 7 (Golgi complex-associated protein of 16 kDa) | GOLGA7 | Golgi to plasma membrane protein transport [GO:0043001]; Golgi to plasma membrane transport [GO:0006893]; peptidyl-L-cysteine S-palmitoylation [GO:0018230]; protein stabilization [GO:0050821]; protein targeting to membrane [GO:0006612] | extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; palmitoyltransferase complex [GO:0002178]; tertiary granule lumen [GO:1904724] | 23093.22332707125 | -0.123464535211649 | 0.759025245839071 | 1 | |
| Q9H8Y8 | Q9H8Y8 | GORS2_HUMAN | Golgi reassembly-stacking protein 2 (GRS2) (Golgi phosphoprotein 6) (GOLPH6) (Golgi reassembly-stacking protein of 55 kDa) (GRASP55) (p59) | GORASP2 | cell differentiation [GO:0030154]; establishment of protein localization to plasma membrane [GO:0061951]; Golgi organization [GO:0007030]; organelle assembly [GO:0070925]; organelle organization [GO:0006996]; response to endoplasmic reticulum stress [GO:0034976]; spermatogenesis [GO:0007283] | cis-Golgi network [GO:0005801]; endoplasmic reticulum membrane [GO:0005789]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; membrane [GO:0016020] | 47836.84257675675 | 0.0635356412807807 | 0.884238888322098 | 1 | |
| O43292 | O43292 | GPAA1_HUMAN | Glycosylphosphatidylinositol anchor attachment 1 protein (GPI anchor attachment protein 1) (GAA1 protein homolog) (hGAA1) | GPAA1 | attachment of GPI anchor to protein [GO:0016255]; protein retention in ER lumen [GO:0006621]; protein-containing complex assembly [GO:0065003] | centrosome [GO:0005813]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; GPI-anchor transamidase complex [GO:0042765]; membrane [GO:0016020]; mitochondrion [GO:0005739] | tubulin binding [GO:0015631] | 13631.4601143515 | -0.045202127323764 | 0.986272756733468 | 1 |
| Q8IXQ4 | Q8IXQ4 | GPAM1_HUMAN | GPALPP motifs-containing protein 1 (Lipopolysaccharide-specific response protein 7) | GPALPP1 | 6040.27225995644 | 0.120150726009609 | 0.73073136836198 | 1 | |||
| Q86UL3 | Q86UL3 | GPAT4_HUMAN | Glycerol-3-phosphate acyltransferase 4 (EC 2.3.1.15) (1-acylglycerol-3-phosphate O-acyltransferase 6) (1-AGP acyltransferase 6) (1-AGPAT 6) (Acyl-CoA:glycerol-3-phosphate acyltransferase 4) (Lysophosphatidic acid acyltransferase zeta) (LPAAT-zeta) (Testis spermatogenesis apoptosis-related protein 7) (TSARG7) | GPAT4 | acyl-CoA metabolic process [GO:0006637]; CDP-diacylglycerol biosynthetic process [GO:0016024]; diacylglycerol metabolic process [GO:0046339]; fatty acid metabolic process [GO:0006631]; glandular epithelial cell maturation [GO:0002071]; lactation [GO:0007595]; lipid biosynthetic process [GO:0008610]; phosphatidic acid biosynthetic process [GO:0006654]; phosphatidylcholine biosynthetic process [GO:0006656]; regulation of multicellular organism growth [GO:0040014]; triglyceride biosynthetic process [GO:0019432] | endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020] | 1-acylglycerol-3-phosphate O-acyltransferase activity [GO:0003841]; glycerol-3-phosphate O-acyltransferase activity [GO:0004366]; sn-1-glycerol-3-phosphate C16:0-DCA-CoA acyl transferase activity [GO:0102420] | 8886.772617376195 | 0.0896044096359594 | 0.934956019585717 | 1 |
| P35052 | P35052 | GPC1_HUMAN | Glypican-1 [Cleaved into: Secreted glypican-1] | GPC1 | cell migration [GO:0016477]; heparan sulfate proteoglycan catabolic process [GO:0030200]; myelin assembly [GO:0032288]; negative regulation of fibroblast growth factor receptor signaling pathway [GO:0040037]; positive regulation of skeletal muscle cell differentiation [GO:2001016]; regulation of protein localization to membrane [GO:1905475]; Schwann cell differentiation [GO:0014037] | cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; lysosomal lumen [GO:0043202]; membrane raft [GO:0045121]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; side of membrane [GO:0098552]; synapse [GO:0045202] | copper ion binding [GO:0005507]; fibroblast growth factor binding [GO:0017134]; laminin binding [GO:0043236] | 12104.2692879778 | -0.0319417149963395 | 0.9636733188096 | 1 |
| P43304 | P43304 | GPDM_HUMAN | Glycerol-3-phosphate dehydrogenase, mitochondrial (GPD-M) (GPDH-M) (EC 1.1.5.3) (mitohondrial glycerophosphate dehydrogenase gene) (mGDH) (mtGPD) | GPD2 | glycerol catabolic process [GO:0019563]; glycerol-3-phosphate metabolic process [GO:0006072]; glycerophosphate shuttle [GO:0006127] | glycerol-3-phosphate dehydrogenase complex [GO:0009331]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739] | calcium ion binding [GO:0005509]; glycerol-3-phosphate dehydrogenase (quinone) activity [GO:0004368] | 9524.256170265118 | 0.0358867610430149 | 0.99996845834563 | 1 |
| Q9NQX3 | Q9NQX3 | GEPH_HUMAN | Gephyrin [Includes: Molybdopterin adenylyltransferase (MPT adenylyltransferase) (EC 2.7.7.75) (Domain G); Molybdopterin molybdenumtransferase (MPT Mo-transferase) (EC 2.10.1.1) (Domain E)] | GPHN | establishment of synaptic specificity at neuromuscular junction [GO:0007529]; gamma-aminobutyric acid receptor clustering [GO:0097112]; glycine receptor clustering [GO:0072579]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; molybdopterin cofactor biosynthetic process [GO:0032324]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; response to metal ion [GO:0010038] | cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendrite [GO:0030425]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; postsynaptic specialization [GO:0099572]; postsynaptic specialization membrane [GO:0099634]; synaptic membrane [GO:0097060] | ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin cofactor binding [GO:0043546]; molybdopterin molybdotransferase activity [GO:0061599]; nitrate reductase activity [GO:0008940] | 8753.89762963063 | -0.115291053385995 | 0.946545811985614 | 1 |
| Q92917 | Q92917 | GPKOW_HUMAN | G-patch domain and KOW motifs-containing protein (G-patch domain-containing protein 5) (Protein MOS2 homolog) (Protein T54) | GPKOW | mRNA splicing, via spliceosome [GO:0000398] | nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spliceosomal complex [GO:0005681] | RNA binding [GO:0003723] | 3960.245804761105 | 0.0857074064592978 | 0.973371323142239 | 1 |
| Q13098 | Q13098 | CSN1_HUMAN | COP9 signalosome complex subunit 1 (SGN1) (Signalosome subunit 1) (G protein pathway suppressor 1) (GPS-1) (JAB1-containing signalosome subunit 1) (Protein MFH) | GPS1 | JNK cascade [GO:0007254]; protein deneddylation [GO:0000338]; protein neddylation [GO:0045116]; regulation of protein neddylation [GO:2000434] | COP9 signalosome [GO:0008180]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] | GTPase inhibitor activity [GO:0005095] | 37574.70027693175 | -0.013212549783209 | 0.999900070035403 | 1 |
| Q86YR5 | Q86YR5 | GPSM1_HUMAN | G-protein-signaling modulator 1 (Activator of G-protein signaling 3) | GPSM1 | cell differentiation [GO:0030154]; establishment of mitotic spindle orientation [GO:0000132]; negative regulation of GTPase activity [GO:0034260]; negative regulation of guanyl-nucleotide exchange factor activity [GO:1905098]; nervous system development [GO:0007399]; positive regulation of macroautophagy [GO:0016239] | cell cortex [GO:0005938]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; Golgi membrane [GO:0000139]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991] | G-protein alpha-subunit binding [GO:0001965]; GDP-dissociation inhibitor activity [GO:0005092] | 6797.691793605015 | 0.00428395638957936 | 0.99999964689573 | 1 |
| P07203 | P07203 | GPX1_HUMAN | Glutathione peroxidase 1 (GPx-1) (GSHPx-1) (EC 1.11.1.9) (Cellular glutathione peroxidase) (Phospholipid-hydroperoxide glutathione peroxidase GPX1) (EC 1.11.1.12) | GPX1 | angiogenesis involved in wound healing [GO:0060055]; arachidonic acid metabolic process [GO:0019369]; biological process involved in interaction with symbiont [GO:0051702]; blood vessel endothelial cell migration [GO:0043534]; cell redox homeostasis [GO:0045454]; cellular response to glucose stimulus [GO:0071333]; cellular response to oxidative stress [GO:0034599]; endothelial cell development [GO:0001885]; epigenetic regulation of gene expression [GO:0040029]; fat cell differentiation [GO:0045444]; fibroblast proliferation [GO:0048144]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide catabolic process [GO:0042744]; intrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631]; lipoxygenase pathway [GO:0019372]; myoblast differentiation [GO:0045445]; myoblast proliferation [GO:0051450]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; neuron apoptotic process [GO:0051402]; positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction [GO:0051897]; positive regulation of supramolecular fiber organization [GO:1902905]; regulation of mammary gland epithelial cell proliferation [GO:0033599]; regulation of proteasomal protein catabolic process [GO:0061136]; response to estradiol [GO:0032355]; response to folic acid [GO:0051593]; response to gamma radiation [GO:0010332]; response to hormone [GO:0009725]; response to hydrogen peroxide [GO:0042542]; response to hydroperoxide [GO:0033194]; response to nicotine [GO:0035094]; response to selenium ion [GO:0010269]; response to symbiotic bacterium [GO:0009609]; response to vitamin E [GO:0033197]; response to xenobiotic stimulus [GO:0009410]; sensory perception of sound [GO:0007605]; skeletal muscle fiber development [GO:0048741]; skeletal muscle tissue regeneration [GO:0043403]; temperature homeostasis [GO:0001659]; triglyceride metabolic process [GO:0006641]; UV protection [GO:0009650]; vasodilation [GO:0042311] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739] | glutathione peroxidase activity [GO:0004602]; phospholipid-hydroperoxide glutathione peroxidase activity [GO:0047066]; SH3 domain binding [GO:0017124] | 52385.99664311959 | -0.0472870128743202 | 0.933311446357587 | 1 |
| Q4V328 | Q4V328 | GRAP1_HUMAN | GRIP1-associated protein 1 (GRASP-1) [Cleaved into: GRASP-1 C-terminal chain (30kDa C-terminus form)] | GRIPAP1 | negative regulation of receptor clustering [GO:1903910]; neurotransmitter receptor transport, endosome to postsynaptic membrane [GO:0098887]; regulation of modification of synaptic structure [GO:1905244]; regulation of neurotransmitter receptor transport, endosome to postsynaptic membrane [GO:0099152]; regulation of recycling endosome localization within postsynapse [GO:0099158] | axon [GO:0030424]; blood microparticle [GO:0072562]; cytosol [GO:0005829]; dendrite [GO:0030425]; extrinsic component of postsynaptic early endosome membrane [GO:0098998]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; postsynaptic recycling endosome [GO:0098837]; presynaptic membrane [GO:0042734]; recycling endosome membrane [GO:0055038] | guanyl-nucleotide exchange factor activity [GO:0005085]; identical protein binding [GO:0042802]; ionotropic glutamate receptor binding [GO:0035255] | 8882.818924878255 | 0.0766548941045005 | 0.999906359834743 | 1 |
| P25098 | P25098 | ARBK1_HUMAN | Beta-adrenergic receptor kinase 1 (Beta-ARK-1) (EC 2.7.11.15) (G-protein coupled receptor kinase 2) | GRK2 | cardiac muscle contraction [GO:0060048]; desensitization of G protein-coupled receptor signaling pathway [GO:0002029]; G protein-coupled acetylcholine receptor signaling pathway [GO:0007213]; G protein-coupled receptor signaling pathway [GO:0007186]; heart development [GO:0007507]; negative regulation of relaxation of smooth muscle [GO:1901081]; negative regulation of striated muscle contraction [GO:0045988]; negative regulation of the force of heart contraction by chemical signal [GO:0003108]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of catecholamine secretion [GO:0033605]; receptor internalization [GO:0031623]; regulation of the force of heart contraction [GO:0002026]; symbiont entry into host cell [GO:0046718]; tachykinin receptor signaling pathway [GO:0007217]; viral genome replication [GO:0019079] | cilium [GO:0005929]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; presynapse [GO:0098793] | alpha-2A adrenergic receptor binding [GO:0031694]; ATP binding [GO:0005524]; beta-adrenergic receptor kinase activity [GO:0047696]; Edg-2 lysophosphatidic acid receptor binding [GO:0031755]; G protein-coupled receptor binding [GO:0001664]; G protein-coupled receptor kinase activity [GO:0004703]; protein kinase activity [GO:0004672] | 8481.493983525645 | -0.0265595519980287 | 0.998299859953221 | 1 |
| O60443 | O60443 | GSDME_HUMAN | Gasdermin-E (Inversely correlated with estrogen receptor expression 1) (ICERE-1) (Non-syndromic hearing impairment protein 5) [Cleaved into: Gasdermin-E, N-terminal (GSDME-NT); Gasdermin-E, C-terminal (GSDME-CT)] | GSDME | cellular response to tumor necrosis factor [GO:0071356]; cellular response to virus [GO:0098586]; inner ear auditory receptor cell differentiation [GO:0042491]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of immune response to tumor cell [GO:0002839]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of MAPK cascade [GO:0043410]; programmed cell death [GO:0012501]; pyroptosis [GO:0070269]; sensory perception of sound [GO:0007605] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886] | cardiolipin binding [GO:1901612]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; wide pore channel activity [GO:0022829] | 18962.639560099647 | 0.0727313043942092 | 0.990930208930652 | 1 |
| P49840 | P49840 | GSK3A_HUMAN | Glycogen synthase kinase-3 alpha (GSK-3 alpha) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3A) (EC 2.7.11.1) | GSK3A | autosome genomic imprinting [GO:0141068]; cardiac left ventricle morphogenesis [GO:0003214]; cell differentiation [GO:0030154]; cell migration [GO:0016477]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to interleukin-3 [GO:0036016]; cellular response to lithium ion [GO:0071285]; dopamine receptor signaling pathway [GO:0007212]; excitatory postsynaptic potential [GO:0060079]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; glycogen metabolic process [GO:0005977]; insulin receptor signaling pathway [GO:0008286]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell growth involved in cardiac muscle cell development [GO:0061052]; negative regulation of glucose import [GO:0046325]; negative regulation of glycogen (starch) synthase activity [GO:2000466]; negative regulation of glycogen biosynthetic process [GO:0045719]; negative regulation of glycogen synthase activity, transferring glucose-1-phosphate [GO:1904227]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of neuron projection development [GO:0010977]; negative regulation of TOR signaling [GO:0032007]; negative regulation of type B pancreatic cell development [GO:2000077]; negative regulation of UDP-glucose catabolic process [GO:0010905]; nervous system development [GO:0007399]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071879]; positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0106071]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of autophagy [GO:0010508]; positive regulation of gene expression [GO:0010628]; positive regulation of glycogen (starch) synthase activity [GO:2000467]; positive regulation of heart contraction [GO:0045823]; positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901030]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein targeting to mitochondrion [GO:1903955]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription by RNA polymerase II [GO:0045944]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein phosphorylation [GO:0006468]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of mitophagy [GO:1901524]; regulation of systemic arterial blood pressure [GO:0003073]; viral protein processing [GO:0019082]; Wnt signaling pathway [GO:0016055] | apical dendrite [GO:0097440]; axon [GO:0030424]; beta-catenin destruction complex [GO:0030877]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; postsynapse [GO:0098794]; proximal dendrite [GO:1990635] | ATP binding [GO:0005524]; protein kinase A catalytic subunit binding [GO:0034236]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; signaling receptor binding [GO:0005102]; tau protein binding [GO:0048156]; tau-protein kinase activity [GO:0050321] | 9800.521651146915 | -0.103683285512523 | 0.8989956317278 | 1 |
| P49841 | P49841 | GSK3B_HUMAN | Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3B) (EC 2.7.11.1) | GSK3B | beta-catenin destruction complex disassembly [GO:1904886]; canonical Wnt signaling pathway [GO:0060070]; cell differentiation [GO:0030154]; cellular response to amyloid-beta [GO:1904646]; cellular response to interleukin-3 [GO:0036016]; cellular response to retinoic acid [GO:0071300]; circadian rhythm [GO:0007623]; dopamine receptor signaling pathway [GO:0007212]; epithelial to mesenchymal transition [GO:0001837]; ER overload response [GO:0006983]; establishment of cell polarity [GO:0030010]; excitatory postsynaptic potential [GO:0060079]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; glycogen metabolic process [GO:0005977]; heart valve development [GO:0003170]; hippocampus development [GO:0021766]; insulin receptor signaling pathway [GO:0008286]; intracellular signal transduction [GO:0035556]; maintenance of cell polarity [GO:0030011]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of dopaminergic neuron differentiation [GO:1904339]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of gene expression [GO:0010629]; negative regulation of glycogen (starch) synthase activity [GO:2000466]; negative regulation of glycogen biosynthetic process [GO:0045719]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of mesenchymal stem cell differentiation [GO:2000740]; negative regulation of neuron projection development [GO:0010977]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; negative regulation of protein acetylation [GO:1901984]; negative regulation of protein localization to nucleus [GO:1900181]; negative regulation of protein-containing complex assembly [GO:0031333]; negative regulation of TOR signaling [GO:0032007]; negative regulation of type B pancreatic cell development [GO:2000077]; neuron projection development [GO:0031175]; neuron projection organization [GO:0106027]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of autophagy [GO:0010508]; positive regulation of cell differentiation [GO:0045597]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of cilium assembly [GO:0045724]; positive regulation of gene expression [GO:0010628]; positive regulation of GTPase activity [GO:0043547]; positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901030]; positive regulation of mitochondrion organization [GO:0010822]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein binding [GO:0032092]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein localization to centrosome [GO:1904781]; positive regulation of protein localization to cilium [GO:1903566]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of protein-containing complex assembly [GO:0031334]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of axon extension [GO:0030516]; regulation of axonogenesis [GO:0050770]; regulation of cellular response to heat [GO:1900034]; regulation of circadian rhythm [GO:0042752]; regulation of dendrite morphogenesis [GO:0048814]; regulation of long-term synaptic potentiation [GO:1900271]; regulation of microtubule anchoring at centrosome [GO:0150101]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of microtubule-based process [GO:0032886]; regulation of protein export from nucleus [GO:0046825]; superior temporal gyrus development [GO:0071109]; viral protein processing [GO:0019082] | axon [GO:0030424]; beta-catenin destruction complex [GO:0030877]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; presynapse [GO:0098793]; Wnt signalosome [GO:1990909] | ATP binding [GO:0005524]; beta-catenin binding [GO:0008013]; dynactin binding [GO:0034452]; kinase activity [GO:0016301]; NF-kappaB binding [GO:0051059]; p53 binding [GO:0002039]; protease binding [GO:0002020]; protein kinase A catalytic subunit binding [GO:0034236]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; tau protein binding [GO:0048156]; tau-protein kinase activity [GO:0050321]; ubiquitin protein ligase binding [GO:0031625] | 19601.782017775753 | 0.0648029910369571 | 0.893332771093206 | 1 |
| P15170 | P15170 | ERF3A_HUMAN | Eukaryotic peptide chain release factor GTP-binding subunit ERF3A (Eukaryotic peptide chain release factor subunit 3a) (eRF3a) (EC 3.6.5.-) (G1 to S phase transition protein 1 homolog) | GSPT1 | G1/S transition of mitotic cell cycle [GO:0000082]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; protein methylation [GO:0006479]; regulation of translational termination [GO:0006449]; translation [GO:0006412]; translational termination [GO:0006415] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic ribosome [GO:0022626]; translation release factor complex [GO:0018444] | GTP binding [GO:0005525]; GTPase activity [GO:0003924]; RNA binding [GO:0003723]; translation release factor activity [GO:0003747] | 33882.28434580755 | 0.0925690339509877 | 0.900155368621209 | 1 |
| P48637 | P48637 | GSHB_HUMAN | Glutathione synthetase (GSH synthetase) (GSH-S) (EC 6.3.2.3) (Glutathione synthase) | GSS | amino acid metabolic process [GO:0006520]; nervous system development [GO:0007399]; response to cadmium ion [GO:0046686]; response to oxidative stress [GO:0006979] | cytosol [GO:0005829]; extracellular exosome [GO:0070062] | ATP binding [GO:0005524]; glutathione binding [GO:0043295]; glutathione synthase activity [GO:0004363]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803] | 36232.157409674895 | 0.0386348946482762 | 0.993569645020363 | 1 |
| P52655 | P52655 | TF2AA_HUMAN | Transcription initiation factor IIA subunit 1 (General transcription factor IIA subunit 1) (TFIIAL) (Transcription initiation factor TFIIA 42 kDa subunit) (TFIIA-42) [Cleaved into: Transcription initiation factor IIA alpha chain (TFIIA p35 subunit); Transcription initiation factor IIA beta chain (TFIIA p19 subunit)] | GTF2A1 | positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription initiation by RNA polymerase II [GO:0060261]; RNA polymerase II preinitiation complex assembly [GO:0051123]; transcription by RNA polymerase II [GO:0006366] | cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor TFIIA complex [GO:0005672]; transcription factor TFIID complex [GO:0005669]; transcription preinitiation complex [GO:0097550] | DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; RNA polymerase II general transcription initiation factor binding [GO:0001091]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; TBP-class protein binding [GO:0017025] | 39224.203968042304 | -0.362731281246289 | 0.993812733233576 | 1 |
| P29083 | P29083 | T2EA_HUMAN | General transcription factor IIE subunit 1 (General transcription factor IIE 56 kDa subunit) (Transcription initiation factor IIE subunit alpha) (TFIIE-alpha) | GTF2E1 | transcription by RNA polymerase II [GO:0006366]; transcription initiation at RNA polymerase II promoter [GO:0006367]; transcription open complex formation at RNA polymerase II promoter [GO:0001113] | cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor TFIID complex [GO:0005669]; transcription factor TFIIE complex [GO:0005673] | metal ion binding [GO:0046872]; RNA polymerase II general transcription initiation factor activity [GO:0016251] | 2930.64798644149 | 0.171775475105883 | 0.934899377039644 | 1 |
| P29084 | P29084 | T2EB_HUMAN | Transcription initiation factor IIE subunit beta (TFIIE-beta) (General transcription factor IIE subunit 2) | GTF2E2 | transcription by RNA polymerase II [GO:0006366]; transcription initiation at RNA polymerase II promoter [GO:0006367] | cytosol [GO:0005829]; nucleoplasm [GO:0005654]; transcription factor TFIID complex [GO:0005669]; transcription factor TFIIE complex [GO:0005673] | DNA binding [GO:0003677]; RNA binding [GO:0003723]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; TFIIH-class transcription factor complex binding [GO:0001097] | 5399.065312555174 | 0.011850062531764 | 0.958546669962541 | 1 |
| P35269 | P35269 | T2FA_HUMAN | General transcription factor IIF subunit 1 (General transcription factor IIF 74 kDa subunit) (Transcription initiation factor IIF subunit alpha) (TFIIF-alpha) (Transcription initiation factor RAP74) | GTF2F1 | negative regulation of protein binding [GO:0032091]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation by RNA polymerase II [GO:0032968]; response to virus [GO:0009615]; transcription by RNA polymerase II [GO:0006366]; transcription elongation by RNA polymerase II [GO:0006368]; transcription initiation at RNA polymerase II promoter [GO:0006367] | cell junction [GO:0030054]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcription factor TFIID complex [GO:0005669]; transcription factor TFIIF complex [GO:0005674] | DNA binding [GO:0003677]; phosphatase activator activity [GO:0019211]; promoter-specific chromatin binding [GO:1990841]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; RNA polymerase II general transcription initiation factor binding [GO:0001091]; TFIIF-class transcription factor complex binding [GO:0001096] | 13077.17711238405 | -0.0114456232262232 | 0.999850370441769 | 1 |
| P13984 | P13984 | T2FB_HUMAN | General transcription factor IIF subunit 2 (General transcription factor IIF 30 kDa subunit) (Transcription initiation factor IIF subunit beta) (TFIIF-beta) (Transcription initiation factor RAP30) | GTF2F2 | positive regulation of transcription by RNA polymerase II [GO:0045944]; transcription by RNA polymerase II [GO:0006366]; transcription elongation by RNA polymerase II [GO:0006368]; transcription initiation at RNA polymerase II promoter [GO:0006367] | microtubule cytoskeleton [GO:0015630]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor TFIIF complex [GO:0005674] | DNA binding [GO:0003677]; RNA polymerase II general transcription initiation factor activity [GO:0016251] | 6934.846736442225 | 0.141860157658238 | 0.829169691067979 | 1 |
| Q13888;Q6P1K8 | Q13888 | TF2H2_HUMAN | General transcription factor IIH subunit 2 (Basic transcription factor 2 44 kDa subunit) (BTF2 p44) (General transcription factor IIH polypeptide 2) (TFIIH basal transcription factor complex p44 subunit) | GTF2H2 | G protein-coupled receptor internalization [GO:0002031]; nucleotide-excision repair [GO:0006289]; regulation of transcription by RNA polymerase II [GO:0006357]; response to UV [GO:0009411]; transcription by RNA polymerase II [GO:0006366]; transcription initiation at RNA polymerase II promoter [GO:0006367] | core TFIIH complex portion of holo TFIIH complex [GO:0000438]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor TFIID complex [GO:0005669]; transcription factor TFIIH core complex [GO:0000439]; transcription factor TFIIH holo complex [GO:0005675] | RNA polymerase II general transcription initiation factor activity [GO:0016251]; zinc ion binding [GO:0008270] | 5683.109018366946 | -0.0753783751447115 | 0.743842841424711 | 1 |
| P78347 | P78347 | GTF2I_HUMAN | General transcription factor II-I (GTFII-I) (TFII-I) (Bruton tyrosine kinase-associated protein 135) (BAP-135) (BTK-associated protein 135) (SRF-Phox1-interacting protein) (SPIN) (Williams-Beuren syndrome chromosomal region 6 protein) | GTF2I | negative regulation of angiogenesis [GO:0016525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; transcription by RNA polymerase II [GO:0006366] | cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] | DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629] | 15911.180894809451 | -0.14601476674155 | 0.860907517797909 | 1 |
| Q9Y5Q9 | Q9Y5Q9 | TF3C3_HUMAN | General transcription factor 3C polypeptide 3 (Transcription factor IIIC 102 kDa subunit) (TFIIIC 102 kDa subunit) (TFIIIC102) (Transcription factor IIIC subunit gamma) (TF3C-gamma) | GTF3C3 | 5S class rRNA transcription by RNA polymerase III [GO:0042791]; transcription by RNA polymerase III [GO:0006383]; tRNA transcription by RNA polymerase III [GO:0042797] | fibrillar center [GO:0001650]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; transcription factor TFIIIC complex [GO:0000127] | DNA binding [GO:0003677]; RNA polymerase III general transcription initiation factor activity [GO:0000995] | 1077.6749465082048 | -1.57523357963029 | 0.945155044275958 | 1 |
| O00178 | O00178 | GTPB1_HUMAN | GTP-binding protein 1 (G-protein 1) (GP-1) (GP1) | GTPBP1 | cytoplasmic translation [GO:0002181]; GTP metabolic process [GO:0046039]; immune response [GO:0006955]; positive regulation of mRNA catabolic process [GO:0061014]; signal transduction [GO:0007165]; translational elongation [GO:0006414] | cytoplasmic exosome (RNase complex) [GO:0000177]; cytosol [GO:0005829]; membrane [GO:0016020] | alpha-aminoacyl-tRNA binding [GO:1904678]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; RNA binding [GO:0003723]; translation elongation factor activity [GO:0003746]; tRNA binding [GO:0000049] | 11887.11785102325 | -0.0515260561182734 | 0.984521074594131 | 1 |
| Q9BZE4 | Q9BZE4 | GTPB4_HUMAN | GTP-binding protein 4 (Chronic renal failure gene protein) (GTP-binding protein NGB) (Nucleolar GTP-binding protein 1) | GTPBP4 | maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000463]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of collagen binding [GO:0033342]; negative regulation of DNA replication [GO:0008156]; negative regulation of protein ubiquitination [GO:0031397]; osteoblast differentiation [GO:0001649]; protein stabilization [GO:0050821]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; ribosomal large subunit biogenesis [GO:0042273] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471] | GTP binding [GO:0005525]; GTPase activity [GO:0003924]; preribosome binding [GO:1990275]; RNA binding [GO:0003723] | 16046.83929950395 | -0.0686857794178432 | 0.937626572970053 | 1 |
| P08236 | P08236 | BGLR_HUMAN | Beta-glucuronidase (EC 3.2.1.31) (Beta-G1) | GUSB | carbohydrate metabolic process [GO:0005975]; chondroitin sulfate catabolic process [GO:0030207]; glucuronoside catabolic process [GO:0019391]; glycosaminoglycan catabolic process [GO:0006027]; heparan sulfate proteoglycan catabolic process [GO:0030200]; hyaluronan catabolic process [GO:0030214] | azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; membrane [GO:0016020] | beta-glucuronidase activity [GO:0004566]; carbohydrate binding [GO:0030246]; protein domain specific binding [GO:0019904]; signaling receptor binding [GO:0005102] | 13742.00243163375 | 6.3231599985173E-4 | 0.99999997594994 | 1 |
| Q4G148 | Q4G148 | GXLT1_HUMAN | Glucoside xylosyltransferase 1 (EC 2.4.2.42) (Glycosyltransferase 8 domain-containing protein 3) | GXYLT1 | O-glycan processing [GO:0016266] | membrane [GO:0016020] | UDP-D-xylose:beta-D-glucoside alpha-1,3-D-xylosyltransferase activity [GO:0140563]; UDP-xylosyltransferase activity [GO:0035252] | 3063.617549800315 | -0.099025619446667 | 0.77949635934082 | 1 |
| P16401 | P16401 | H15_HUMAN | Histone H1.5 (Histone H1a) (Histone H1b) (Histone H1s-3) | H1-5 | chromatin organization [GO:0006325]; chromosome condensation [GO:0030261]; establishment of protein localization to chromatin [GO:0071169]; muscle organ development [GO:0007517]; negative regulation of DNA recombination [GO:0045910]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleosome assembly [GO:0006334]; protein stabilization [GO:0050821] | chromatin [GO:0000785]; chromosome [GO:0005694]; heterochromatin [GO:0000792]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634] | chromatin DNA binding [GO:0031490]; double-stranded DNA binding [GO:0003690]; histone deacetylase binding [GO:0042826]; nucleosomal DNA binding [GO:0031492]; RNA binding [GO:0003723]; structural constituent of chromatin [GO:0030527] | 192620.147033562 | 0.13313897258018 | 0.755795902853029 | 1 |
| P0C0S5;Q71UI9 | P0C0S5 | H2AZ_HUMAN | Histone H2A.Z (H2A/z) | H2AZ1 | cellular response to estradiol stimulus [GO:0071392]; chromatin organization [GO:0006325]; heterochromatin organization [GO:0070828]; positive regulation of transcription by RNA polymerase II [GO:0045944] | euchromatin [GO:0000791]; extracellular exosome [GO:0070062]; heterochromatin [GO:0000792]; nucleosome [GO:0000786]; nucleus [GO:0005634] | chromatin DNA binding [GO:0031490]; nucleosomal DNA binding [GO:0031492]; protein heterodimerization activity [GO:0046982]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; structural constituent of chromatin [GO:0030527] | 71601.9614444366 | -0.0143958443623126 | 0.994725277772725 | 1 |
| P06899;P23527;P33778;Q16778;Q8N257 | P06899 | H2B1J_HUMAN | Histone H2B type 1-J (Histone H2B.1) (Histone H2B.r) (H2B/r) | H2BC11 | antibacterial humoral response [GO:0019731]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; chromatin organization [GO:0006325]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response in mucosa [GO:0002227]; killing of cells of another organism [GO:0031640]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; nucleosome assembly [GO:0006334]; protein localization to CENP-A containing chromatin [GO:0061644] | CENP-A containing nucleosome [GO:0043505]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634] | DNA binding [GO:0003677]; lipopolysaccharide binding [GO:0001530]; protein heterodimerization activity [GO:0046982]; structural constituent of chromatin [GO:0030527] | 573050.701560506 | 0.0868616772843958 | 0.78771677373108 | 1 |
| O60814;P57053;P58876;P62807;Q5QNW6;Q93079;Q99877;Q99879;Q99880 | O60814 | H2B1K_HUMAN | Histone H2B type 1-K (H2B K) (HIRA-interacting protein 1) | H2BC12 | antibacterial humoral response [GO:0019731]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response in mucosa [GO:0002227]; killing of cells of another organism [GO:0031640] | cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634] | DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]; structural constituent of chromatin [GO:0030527] | 537160.2311755505 | 0.0963138260443217 | 0.875621821781701 | 1 |
| Q5TEC6 | Q5TEC6 | H37_HUMAN | Histone H3-7 | H3-7 | nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634] | DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]; structural constituent of chromatin [GO:0030527] | 103421.74779791594 | 0.0779251190538543 | 0.868637867629301 | 1 | |
| P68431 | P68431 | H31_HUMAN | Histone H3.1 (Histone H3/a) (Histone H3/b) (Histone H3/c) (Histone H3/d) (Histone H3/f) (Histone H3/h) (Histone H3/i) (Histone H3/j) (Histone H3/k) (Histone H3/l) | H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12 | chromatin organization [GO:0006325]; epigenetic regulation of gene expression [GO:0040029]; gene expression [GO:0010467]; nucleosome assembly [GO:0006334]; telomere organization [GO:0032200] | extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991] | cadherin binding [GO:0045296]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]; structural constituent of chromatin [GO:0030527] | 550672.02216243 | 0.0415513267213096 | 0.945115042896757 | 1 |
| P62805 | P62805 | H4_HUMAN | Histone H4 | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | chromatin organization [GO:0006325]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein localization to CENP-A containing chromatin [GO:0061644]; telomere organization [GO:0032200] | CENP-A containing nucleosome [GO:0043505]; chromosome, telomeric region [GO:0000781]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991] | DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; structural constituent of chromatin [GO:0030527] | 190387.35632355697 | -0.112584668201972 | 0.708493737197008 | 1 |
| P40939 | P40939 | ECHA_HUMAN | Trifunctional enzyme subunit alpha, mitochondrial (78 kDa gastrin-binding protein) (Monolysocardiolipin acyltransferase) (EC 2.3.1.-) (TP-alpha) [Includes: Long-chain enoyl-CoA hydratase (EC 4.2.1.17); Long chain 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.211)] | HADHA | cardiolipin acyl-chain remodeling [GO:0035965]; fatty acid beta-oxidation [GO:0006635]; response to insulin [GO:0032868]; response to xenobiotic stimulus [GO:0009410] | mitochondrial fatty acid beta-oxidation multienzyme complex [GO:0016507]; mitochondrial inner membrane [GO:0005743]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739] | 3-hydroxyacyl-CoA dehydratase activity [GO:0018812]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; enoyl-CoA hydratase activity [GO:0004300]; fatty-acyl-CoA binding [GO:0000062]; long-chain-3-hydroxyacyl-CoA dehydrogenase activity [GO:0016509]; NAD+ binding [GO:0070403]; protein-containing complex binding [GO:0044877] | 57777.46315280815 | 0.0117251173115252 | 0.99999999925586 | 1 |
| Q16775 | Q16775 | GLO2_HUMAN | Hydroxyacylglutathione hydrolase, mitochondrial (EC 3.1.2.6) (Glyoxalase II) (Glx II) | HAGH | glutathione biosynthetic process [GO:0006750]; glutathione metabolic process [GO:0006749]; methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione [GO:0019243] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739] | hydroxyacylglutathione hydrolase activity [GO:0004416]; metal ion binding [GO:0046872] | 29834.3208725461 | 0.0176115147278695 | 0.999216377733043 | 1 |
| P12081 | P12081 | HARS1_HUMAN | Histidine--tRNA ligase, cytoplasmic (EC 6.1.1.21) (Histidyl-tRNA synthetase) (HisRS) | HARS1 | histidyl-tRNA aminoacylation [GO:0006427]; mitochondrial translation [GO:0032543]; translation [GO:0006412]; tRNA aminoacylation for protein translation [GO:0006418] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739] | ATP binding [GO:0005524]; histidine-tRNA ligase activity [GO:0004821]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723] | 61354.84597187955 | -0.0739442716437178 | 0.856265752617801 | 1 |
| O00165 | O00165 | HAX1_HUMAN | HCLS1-associated protein X-1 (HS1-associating protein X-1) (HAX-1) (HS1-binding protein 1) (HSP1BP-1) | HAX1 | cellular response to cytokine stimulus [GO:0071345]; granulocyte colony-stimulating factor signaling pathway [GO:0038158]; negative regulation of apoptotic process [GO:0043066]; positive regulation of granulocyte differentiation [GO:0030854]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction [GO:0051897]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of actin filament organization [GO:0110053]; regulation of actin filament polymerization [GO:0030833]; regulation of apoptotic process [GO:0042981]; regulation of autophagy of mitochondrion [GO:1903146]; regulation of protein targeting to mitochondrion [GO:1903214] | actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; cell cortex [GO:0005938]; clathrin-coated vesicle [GO:0030136]; endoplasmic reticulum [GO:0005783]; lamellipodium [GO:0030027]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; P-body [GO:0000932]; sarcoplasmic reticulum [GO:0016529]; transcription regulator complex [GO:0005667] | interleukin-1 binding [GO:0019966]; signaling adaptor activity [GO:0035591] | 4903.982606157035 | 0.0372085656112182 | 0.999786366444075 | 1 |
| Q9Y450 | Q9Y450 | HBS1L_HUMAN | HBS1-like protein (EC 3.6.5.-) (ERFS) | HBS1L | nuclear-transcribed mRNA catabolic process, no-go decay [GO:0070966]; rescue of stalled ribosome [GO:0072344]; ribosome disassembly [GO:0032790]; signal transduction [GO:0007165]; translation [GO:0006412] | cytosol [GO:0005829]; cytosolic ribosome [GO:0022626]; Dom34-Hbs1 complex [GO:1990533]; extracellular exosome [GO:0070062]; membrane [GO:0016020] | GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746] | 15655.109996623549 | 0.0674093200811911 | 0.935503254565141 | 1 |
| P51610 | P51610 | HCFC1_HUMAN | Host cell factor 1 (HCF) (HCF-1) (C1 factor) (CFF) (VCAF) (VP16 accessory protein) [Cleaved into: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N-terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C-terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6] | HCFC1 | cell cycle [GO:0007049]; chromatin remodeling [GO:0006338]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of cell cycle [GO:0045787]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein stabilization [GO:0050821]; regulation of DNA-templated transcription [GO:0006355]; regulation of protein-containing complex assembly [GO:0043254]; release from viral latency [GO:0019046] | cytoplasm [GO:0005737]; histone acetyltransferase complex [GO:0000123]; histone methyltransferase complex [GO:0035097]; membrane [GO:0016020]; MLL1 complex [GO:0071339]; MLL1/2 complex [GO:0044665]; neuronal cell body [GO:0043025]; NSL complex [GO:0044545]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; Set1C/COMPASS complex [GO:0048188] | cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; DNA-binding transcription factor binding [GO:0140297]; identical protein binding [GO:0042802]; protein-macromolecule adaptor activity [GO:0030674]; transcription coactivator activity [GO:0003713] | 10963.8280918655 | -0.0550819467563847 | 0.981933120617793 | 1 |
| Q13547 | Q13547 | HDAC1_HUMAN | Histone deacetylase 1 (HD1) (EC 3.5.1.98) (Protein deacetylase HDAC1) (EC 3.5.1.-) (Protein decrotonylase HDAC1) (EC 3.5.1.-) | HDAC1 | cellular response to platelet-derived growth factor stimulus [GO:0036120]; chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; circadian regulation of gene expression [GO:0032922]; DNA methylation-dependent heterochromatin formation [GO:0006346]; embryonic digit morphogenesis [GO:0042733]; endoderm development [GO:0007492]; epidermal cell differentiation [GO:0009913]; eyelid development in camera-type eye [GO:0061029]; fungiform papilla formation [GO:0061198]; hair follicle placode formation [GO:0060789]; hippocampus development [GO:0021766]; negative regulation by host of viral transcription [GO:0043922]; negative regulation of androgen receptor signaling pathway [GO:0060766]; negative regulation of apoptotic process [GO:0043066]; negative regulation of canonical NF-kappaB signal transduction [GO:0043124]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell migration [GO:0030336]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of gene expression [GO:0010629]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of stem cell population maintenance [GO:1902455]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron differentiation [GO:0030182]; odontogenesis of dentin-containing tooth [GO:0042475]; oligodendrocyte differentiation [GO:0048709]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of gene expression [GO:0010628]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of signaling receptor activity [GO:2000273]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of stem cell population maintenance [GO:1902459]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deacetylation [GO:0006476]; regulation of cell fate specification [GO:0042659]; regulation of stem cell differentiation [GO:2000736]; regulation of transcription by RNA polymerase II [GO:0006357] | chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; heterochromatin [GO:0000792]; histone deacetylase complex [GO:0000118]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; NuRD complex [GO:0016581]; protein-containing complex [GO:0032991]; Sin3-type complex [GO:0070822]; transcription repressor complex [GO:0017053] | core promoter sequence-specific DNA binding [GO:0001046]; DNA-binding transcription factor binding [GO:0140297]; E-box binding [GO:0070888]; enzyme binding [GO:0019899]; histone deacetylase activity [GO:0004407]; histone deacetylase binding [GO:0042826]; histone decrotonylase activity [GO:0160009]; Krueppel-associated box domain binding [GO:0035851]; NF-kappaB binding [GO:0051059]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protein lysine deacetylase activity [GO:0033558]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; transcription corepressor activity [GO:0003714]; transcription corepressor binding [GO:0001222] | 16178.65160312895 | 0.00747044013757302 | 0.999999999228225 | 1 |
| Q92769 | Q92769 | HDAC2_HUMAN | Histone deacetylase 2 (HD2) (EC 3.5.1.98) (Protein deacylase HDAC2) (EC 3.5.1.-) | HDAC2 | behavioral response to ethanol [GO:0048149]; cardiac muscle hypertrophy [GO:0003300]; cellular response to dopamine [GO:1903351]; cellular response to heat [GO:0034605]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to retinoic acid [GO:0071300]; cellular response to transforming growth factor beta stimulus [GO:0071560]; chromatin remodeling [GO:0006338]; circadian regulation of gene expression [GO:0032922]; dendrite development [GO:0016358]; embryonic digit morphogenesis [GO:0042733]; epidermal cell differentiation [GO:0009913]; eyelid development in camera-type eye [GO:0061029]; fungiform papilla formation [GO:0061198]; hair follicle placode formation [GO:0060789]; heterochromatin formation [GO:0031507]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell migration [GO:0030336]; negative regulation of dendritic spine development [GO:0061000]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of MHC class II biosynthetic process [GO:0045347]; negative regulation of neuron projection development [GO:0010977]; negative regulation of peptidyl-lysine acetylation [GO:2000757]; negative regulation of stem cell population maintenance [GO:1902455]; negative regulation of transcription by competitive promoter binding [GO:0010944]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of interleukin-1 production [GO:0032732]; positive regulation of male mating behavior [GO:1902437]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of proteolysis [GO:0045862]; positive regulation of signaling receptor activity [GO:2000273]; positive regulation of stem cell population maintenance [GO:1902459]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein modification process [GO:0036211]; regulation of cell fate specification [GO:0042659]; regulation of stem cell differentiation [GO:2000736]; response to amphetamine [GO:0001975]; response to amyloid-beta [GO:1904645]; response to caffeine [GO:0031000]; response to cocaine [GO:0042220]; response to hyperoxia [GO:0055093]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]; response to xenobiotic stimulus [GO:0009410] | chromatin [GO:0000785]; chromosome, telomeric region [GO:0000781]; cytoplasm [GO:0005737]; ESC/E(Z) complex [GO:0035098]; histone deacetylase complex [GO:0000118]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; NuRD complex [GO:0016581]; protein-containing complex [GO:0032991]; Sin3-type complex [GO:0070822] | chromatin binding [GO:0003682]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; histone binding [GO:0042393]; histone deacetylase activity [GO:0004407]; histone deacetylase binding [GO:0042826]; histone decrotonylase activity [GO:0160009]; NF-kappaB binding [GO:0051059]; promoter-specific chromatin binding [GO:1990841]; protein de-2-hydroxyisobutyrylase activity [GO:0160010]; protein lysine deacetylase activity [GO:0033558]; RNA binding [GO:0003723]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629] | 17393.3975684966 | -0.0272807943832218 | 0.718874512529532 | 1 |
| Q7Z4V5 | Q7Z4V5 | HDGR2_HUMAN | Hepatoma-derived growth factor-related protein 2 (HDGF-related protein 2) (HRP-2) (Hepatoma-derived growth factor 2) (HDGF-2) | HDGFL2 | chromatin remodeling [GO:0006338]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA repair-dependent chromatin remodeling [GO:0140861]; muscle cell differentiation [GO:0042692]; muscle organ development [GO:0007517]; positive regulation of cell growth [GO:0030307]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; skeletal muscle tissue regeneration [GO:0043403] | cytoplasm [GO:0005737]; nucleus [GO:0005634] | H3K27me3 modified histone binding [GO:0061628]; H3K9me3 modified histone binding [GO:0062072]; histone reader activity [GO:0140566]; methylated histone binding [GO:0035064] | 20167.736895914 | -0.0272533550897871 | 0.999690487999527 | 1 |
| Q9BXW7 | Q9BXW7 | HDHD5_HUMAN | Haloacid dehalogenase-like hydrolase domain-containing 5 (Cat eye syndrome critical region protein 5) | HDHD5 | glycerophospholipid biosynthetic process [GO:0046474] | mitochondrion [GO:0005739] | 14583.3985934146 | 0.0193161344138931 | 0.99999537198657 | 1 | |
| Q7Z4Q2 | Q7Z4Q2 | HEAT3_HUMAN | HEAT repeat-containing protein 3 | HEATR3 | erythrocyte maturation [GO:0043249]; protein import into nucleus [GO:0006606]; ribosomal large subunit biogenesis [GO:0042273] | unfolded protein binding [GO:0051082] | 4086.4387134753897 | 0.0799870901156882 | 0.997271218787288 | 1 | |
| Q9P2D3 | Q9P2D3 | HTR5B_HUMAN | HEAT repeat-containing protein 5B | HEATR5B | endocytosis [GO:0006897]; protein localization [GO:0008104]; protein transport [GO:0015031]; retrograde transport, endosome to Golgi [GO:0042147] | clathrin-coated vesicle [GO:0030136]; cytosol [GO:0005829]; endocytic vesicle [GO:0030139]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nuclear speck [GO:0016607]; perinuclear region of cytoplasm [GO:0048471] | 1125.3971990129248 | -0.208179320482557 | 0.888634622774912 | 1 | |
| Q6AI08 | Q6AI08 | HEAT6_HUMAN | HEAT repeat-containing protein 6 (Amplified in breast cancer protein 1) | HEATR6 | RNA binding [GO:0003723] | 3475.071253869045 | -0.238803592998273 | 0.931905660134185 | 1 | ||
| Q9ULT8 | Q9ULT8 | HECD1_HUMAN | E3 ubiquitin-protein ligase HECTD1 (EC 2.3.2.26) (E3 ligase for inhibin receptor) (EULIR) (HECT domain-containing protein 1) | HECTD1 | aorta development [GO:0035904]; heart valve development [GO:0003170]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K63-linked ubiquitination [GO:0070534]; ventricular septum development [GO:0003281] | nuclear speck [GO:0016607] | metal ion binding [GO:0046872]; ubiquitin protein ligase activity [GO:0061630] | 5974.464261535 | -0.139755756347556 | 0.991498465978684 | 1 |
| Q5T447 | Q5T447 | HECD3_HUMAN | E3 ubiquitin-protein ligase HECTD3 (EC 2.3.2.26) (HECT domain-containing protein 3) (HECT-type E3 ubiquitin transferase HECTD3) | HECTD3 | proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567] | perinuclear region of cytoplasm [GO:0048471] | syntaxin binding [GO:0019905]; ubiquitin-protein transferase activity [GO:0004842] | 10832.461493615101 | 0.100574181498496 | 0.693960112869456 | 1 |
| Q9ULI3 | Q9ULI3 | HEG1_HUMAN | Protein HEG homolog 1 | HEG1 | cardiac atrium morphogenesis [GO:0003209]; cardiac muscle tissue growth [GO:0055017]; cell-cell junction organization [GO:0045216]; endothelial cell morphogenesis [GO:0001886]; heart development [GO:0007507]; in utero embryonic development [GO:0001701]; lung development [GO:0030324]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; multicellular organism growth [GO:0035264]; negative regulation of membrane permeability [GO:1905709]; negative regulation of Rho protein signal transduction [GO:0035024]; negative regulation of Rho-dependent protein serine/threonine kinase activity [GO:2000299]; pericardium development [GO:0060039]; positive regulation of fibroblast growth factor production [GO:0090271]; post-embryonic development [GO:0009791]; protein localization to cell junction [GO:1902414]; regulation of body fluid levels [GO:0050878]; vasculogenesis [GO:0001570]; venous blood vessel morphogenesis [GO:0048845]; ventricular septum development [GO:0003281]; ventricular trabecula myocardium morphogenesis [GO:0003222] | cell-cell junction [GO:0005911]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576] | calcium ion binding [GO:0005509] | 24344.95195851805 | 0.0426995456795467 | 0.93627747107252 | 1 |
| O94992 | O94992 | HEXI1_HUMAN | Protein HEXIM1 (Cardiac lineage protein 1) (Estrogen down-regulated gene 1 protein) (Hexamethylene bis-acetamide-inducible protein 1) (Menage a quatre protein 1) | HEXIM1 | activation of innate immune response [GO:0002218]; heart development [GO:0007507]; innate immune response [GO:0045087]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription elongation by RNA polymerase II [GO:0034244]; negative regulation of viral transcription [GO:0032897]; positive regulation of signal transduction by p53 class mediator [GO:1901798] | 7SK snRNP [GO:0120259]; cytoplasm [GO:0005737]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] | 7SK snRNA binding [GO:0097322]; cyclin-dependent protein serine/threonine kinase inhibitor activity [GO:0004861]; identical protein binding [GO:0042802]; P-TEFb complex binding [GO:0106140]; protein kinase inhibitor activity [GO:0004860]; snRNA binding [GO:0017069] | 13646.9589290247 | 0.0153532343707034 | 0.995989735204881 | 1 |
| O14964 | O14964 | HGS_HUMAN | Hepatocyte growth factor-regulated tyrosine kinase substrate (Hrs) (Protein pp110) | HGS | endocytic recycling [GO:0032456]; endosomal transport [GO:0016197]; macroautophagy [GO:0016236]; membrane fission [GO:0090148]; membrane invagination [GO:0010324]; multivesicular body assembly [GO:0036258]; negative regulation of angiogenesis [GO:0016525]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of platelet-derived growth factor receptor signaling pathway [GO:0010642]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of gene expression [GO:0010628]; protein localization to membrane [GO:0072657]; protein targeting to lysosome [GO:0006622]; protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043328]; receptor internalization [GO:0031623]; regulation of MAP kinase activity [GO:0043405]; regulation of protein catabolic process [GO:0042176]; signal transduction [GO:0007165] | cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome [GO:0005768]; ESCRT-0 complex [GO:0033565]; extracellular exosome [GO:0070062]; lysosome [GO:0005764]; multivesicular body membrane [GO:0032585]; phagocytic vesicle lumen [GO:0097013] | metal ion binding [GO:0046872]; phosphatidylinositol binding [GO:0035091]; protein domain specific binding [GO:0019904]; ubiquitin binding [GO:0043130]; ubiquitin-like protein ligase binding [GO:0044389] | 25458.12929023595 | 0.00489615936858484 | 1 | 1 |
| Q6NVY1 | Q6NVY1 | HIBCH_HUMAN | 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial (EC 3.1.2.4) (3-hydroxyisobutyryl-coenzyme A hydrolase) (HIB-CoA hydrolase) (HIBYL-CoA-H) | HIBCH | branched-chain amino acid catabolic process [GO:0009083]; valine catabolic process [GO:0006574] | mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739] | 3-hydroxyisobutyryl-CoA hydrolase activity [GO:0003860]; hydrolase activity [GO:0016787] | 7823.17584929873 | -0.0712536848515687 | 0.88632016603273 | 1 |
| Q53FT3 | Q53FT3 | HIKES_HUMAN | Protein Hikeshi | HIKESHI | cellular response to heat [GO:0034605]; Golgi organization [GO:0007030]; lung development [GO:0030324]; protein import into nucleus [GO:0006606]; protein transport [GO:0015031] | cytosol [GO:0005829]; nuclear body [GO:0016604]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] | Hsp70 protein binding [GO:0030544]; nuclear import signal receptor activity [GO:0061608] | 10168.447139725275 | -0.0988001461323432 | 0.821324745929949 | 1 |
| P49773 | P49773 | HINT1_HUMAN | Adenosine 5'-monophosphoramidase HINT1 (EC 3.9.1.-) (Desumoylating isopeptidase HINT1) (EC 3.4.22.-) (Histidine triad nucleotide-binding protein 1) (Protein kinase C inhibitor 1) (Protein kinase C-interacting protein 1) (PKCI-1) | HINT1 | intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; positive regulation of calcium-mediated signaling [GO:0050850]; protein desumoylation [GO:0016926]; proteolysis [GO:0006508]; purine ribonucleotide catabolic process [GO:0009154]; regulation of DNA-templated transcription [GO:0006355]; signal transduction [GO:0007165]; sulfur compound metabolic process [GO:0006790] | cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; histone deacetylase complex [GO:0000118]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886] | adenosine 5'-monophosphoramidase activity [GO:0043530]; adenylylsulfatase activity [GO:0047627]; deSUMOylase activity [GO:0016929]; hydrolase activity [GO:0016787]; nucleotide binding [GO:0000166]; protein kinase C binding [GO:0005080] | 74001.49588238884 | 0.112689140725768 | 0.788055240198068 | 1 |
| Q8TCT9 | Q8TCT9 | HM13_HUMAN | Minor histocompatibility antigen H13 (EC 3.4.23.-) (Intramembrane protease 1) (IMP-1) (IMPAS-1) (hIMP1) (Presenilin-like protein 3) (Signal peptide peptidase) | HM13 | cellular response to oxidative stress [GO:0034599]; in utero embryonic development [GO:0001701]; membrane protein proteolysis [GO:0033619]; membrane protein proteolysis involved in retrograde protein transport, ER to cytosol [GO:1904211]; signal peptide processing [GO:0006465] | cell surface [GO:0009986]; cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; lumenal side of endoplasmic reticulum membrane [GO:0098553]; membrane [GO:0016020]; plasma membrane [GO:0005886]; rough endoplasmic reticulum [GO:0005791] | aspartic endopeptidase activity, intramembrane cleaving [GO:0042500]; peptidase activity [GO:0008233]; protein homodimerization activity [GO:0042803]; ubiquitin protein ligase binding [GO:0031625] | 137089.0316246405 | 0.0386732680979675 | 0.980851915567183 | 1 |
| P26583 | P26583 | HMGB2_HUMAN | High mobility group protein B2 (High mobility group protein 2) (HMG-2) | HMGB2 | cell chemotaxis [GO:0060326]; cellular response to lipopolysaccharide [GO:0071222]; chromatin organization [GO:0006325]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; DNA geometric change [GO:0032392]; DNA topological change [GO:0006265]; double-strand break repair via nonhomologous end joining [GO:0006303]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; inflammatory response to antigenic stimulus [GO:0002437]; innate immune response [GO:0045087]; male gonad development [GO:0008584]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleosome assembly [GO:0006334]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of innate immune response [GO:0045089]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of neurogenesis [GO:0050767]; regulation of stem cell proliferation [GO:0072091]; regulation of transcription by RNA polymerase II [GO:0006357]; response to lipopolysaccharide [GO:0032496]; response to steroid hormone [GO:0048545]; spermatid nucleus differentiation [GO:0007289]; V(D)J recombination [GO:0033151] | chromatin [GO:0000785]; condensed chromosome [GO:0000793]; cytoplasm [GO:0005737]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; protein-containing complex [GO:0032991] | chemoattractant activity [GO:0042056]; cis-regulatory region sequence-specific DNA binding [GO:0000987]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA binding, bending [GO:0008301]; DNA-binding transcription factor binding [GO:0140297]; double-stranded DNA binding [GO:0003690]; four-way junction DNA binding [GO:0000400]; non-sequence-specific DNA binding, bending [GO:0044378]; protein domain specific binding [GO:0019904]; RAGE receptor binding [GO:0050786]; RNA binding [GO:0003723]; single-stranded DNA binding [GO:0003697]; supercoiled DNA binding [GO:0097100]; transcription cis-regulatory region binding [GO:0000976]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134] | 60206.80349747215 | 0.0933435227186832 | 0.778806457221912 | 1 |
| P30519 | P30519 | HMOX2_HUMAN | Heme oxygenase 2 (HO-2) (EC 1.14.14.18) [Cleaved into: Heme oxygenase 2 soluble form] | HMOX2 | heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; response to hypoxia [GO:0001666]; response to oxidative stress [GO:0006979] | endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579] | heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872] | 30894.320083267048 | 0.0940467823751119 | 0.752006116089734 | 1 |
| Q13151 | Q13151 | ROA0_HUMAN | Heterogeneous nuclear ribonucleoprotein A0 (hnRNP A0) | HNRNPA0 | 3'-UTR-mediated mRNA stabilization [GO:0070935]; inflammatory response [GO:0006954]; mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; response to lipopolysaccharide [GO:0032496] | catalytic step 2 spliceosome [GO:0071013]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; synapse [GO:0045202] | mRNA 3'-UTR AU-rich region binding [GO:0035925]; mRNA binding [GO:0003729]; protein kinase binding [GO:0019901]; RNA binding [GO:0003723] | 54948.74675684415 | 0.0818849858785123 | 0.901079227806113 | 1 |
| P22626 | P22626 | ROA2_HUMAN | Heterogeneous nuclear ribonucleoproteins A2/B1 (hnRNP A2/B1) | HNRNPA2B1 | G-quadruplex DNA unwinding [GO:0044806]; miRNA transport [GO:1990428]; mRNA export from nucleus [GO:0006406]; mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; mRNA transport [GO:0051028]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of telomerase RNA reverse transcriptase activity [GO:1905663]; positive regulation of telomere maintenance via telomere lengthening [GO:1904358]; primary miRNA processing [GO:0031053]; RNA transport [GO:0050658] | Cajal body [GO:0015030]; catalytic step 2 spliceosome [GO:0071013]; chromosome, telomeric region [GO:0000781]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681] | G-rich strand telomeric DNA binding [GO:0098505]; identical protein binding [GO:0042802]; miRNA binding [GO:0035198]; molecular condensate scaffold activity [GO:0140693]; mRNA 3'-UTR binding [GO:0003730]; N6-methyladenosine-containing RNA reader activity [GO:1990247]; pre-mRNA intronic binding [GO:0097157]; RNA binding [GO:0003723]; single-stranded telomeric DNA binding [GO:0043047] | 141188.885996035 | 0.179867533949242 | 0.735833086283192 | 1 |
| P51991 | P51991 | ROA3_HUMAN | Heterogeneous nuclear ribonucleoprotein A3 (hnRNP A3) | HNRNPA3 | mRNA splicing, via spliceosome [GO:0000398] | catalytic step 2 spliceosome [GO:0071013]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904] | mRNA 3'-UTR binding [GO:0003730]; RNA binding [GO:0003723] | 125219.78463658501 | 0.116894109602771 | 0.870594918496205 | 1 |
| Q14103 | Q14103 | HNRPD_HUMAN | Heterogeneous nuclear ribonucleoprotein D0 (hnRNP D0) (AU-rich element RNA-binding protein 1) | HNRNPD | 3'-UTR-mediated mRNA destabilization [GO:0061158]; cellular response to amino acid stimulus [GO:0071230]; cellular response to estradiol stimulus [GO:0071392]; cellular response to nitric oxide [GO:0071732]; cellular response to putrescine [GO:1904586]; cerebellum development [GO:0021549]; circadian regulation of translation [GO:0097167]; CRD-mediated mRNA stabilization [GO:0070934]; hepatocyte dedifferentiation [GO:1990828]; liver development [GO:0001889]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of gene expression [GO:0010629]; negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900152]; positive regulation of cytoplasmic translation [GO:2000767]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of telomerase RNA reverse transcriptase activity [GO:1905663]; positive regulation of telomere capping [GO:1904355]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of translation [GO:0045727]; regulation of circadian rhythm [GO:0042752]; regulation of DNA-templated transcription [GO:0006355]; regulation of gene expression [GO:0010468]; regulation of telomere maintenance [GO:0032204]; response to calcium ion [GO:0051592]; response to electrical stimulus [GO:0051602]; response to rapamycin [GO:1901355]; response to sodium phosphate [GO:1904383]; RNA catabolic process [GO:0006401]; RNA processing [GO:0006396] | cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; mCRD-mediated mRNA stability complex [GO:0106002]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynaptic density [GO:0014069]; ribonucleoprotein complex [GO:1990904] | chromatin binding [GO:0003682]; histone deacetylase binding [GO:0042826]; minor groove of adenine-thymine-rich DNA binding [GO:0003680]; mRNA 3'-UTR AU-rich region binding [GO:0035925]; RNA binding [GO:0003723]; telomeric DNA binding [GO:0042162] | 37824.3628056539 | 0.142503786773717 | 0.972694289753501 | 1 |
| P52597 | P52597 | HNRPF_HUMAN | Heterogeneous nuclear ribonucleoprotein F (hnRNP F) (Nucleolin-like protein mcs94-1) [Cleaved into: Heterogeneous nuclear ribonucleoprotein F, N-terminally processed] | HNRNPF | mRNA splicing, via spliceosome [GO:0000398]; regulation of RNA splicing [GO:0043484]; RNA processing [GO:0006396] | catalytic step 2 spliceosome [GO:0071013]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ribonucleoprotein complex [GO:1990904]; synapse [GO:0045202] | RNA binding [GO:0003723]; single-stranded RNA binding [GO:0003727] | 27122.88495525715 | -0.051871840077529 | 0.987506592289487 | 1 |
| P55795 | P55795 | HNRH2_HUMAN | Heterogeneous nuclear ribonucleoprotein H2 (hnRNP H2) (FTP-3) (Heterogeneous nuclear ribonucleoprotein H') (hnRNP H') [Cleaved into: Heterogeneous nuclear ribonucleoprotein H2, N-terminally processed] | HNRNPH2 | regulation of RNA splicing [GO:0043484] | cytosol [GO:0005829]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynaptic density [GO:0014069]; ribonucleoprotein complex [GO:1990904] | RNA binding [GO:0003723] | 13720.98934993465 | 0.0146830575668195 | 0.998015235938043 | 1 |
| Q8WVV9 | Q8WVV9 | HNRLL_HUMAN | Heterogeneous nuclear ribonucleoprotein L-like (hnRNPLL) (Stromal RNA-regulating factor) | HNRNPLL | mRNA processing [GO:0006397]; positive regulation of RNA splicing [GO:0033120]; regulation of RNA splicing [GO:0043484] | membrane [GO:0016020]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; synapse [GO:0045202] | mRNA binding [GO:0003729]; RNA binding [GO:0003723] | 9499.229074675315 | -0.0917684952026324 | 0.990194166868454 | 1 |
| P52272 | P52272 | HNRPM_HUMAN | Heterogeneous nuclear ribonucleoprotein M (hnRNP M) | HNRNPM | alternative mRNA splicing, via spliceosome [GO:0000380]; mRNA splicing, via spliceosome [GO:0000398] | catalytic step 2 spliceosome [GO:0071013]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nuclear matrix [GO:0016363]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; paraspeckles [GO:0042382]; spliceosomal complex [GO:0005681]; synapse [GO:0045202] | mRNA binding [GO:0003729]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723] | 71943.99450097405 | -0.0432564554207639 | 0.996448482634736 | 1 |
| O43390 | O43390 | HNRPR_HUMAN | Heterogeneous nuclear ribonucleoprotein R (hnRNP R) | HNRNPR | mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398] | catalytic step 2 spliceosome [GO:0071013]; endoplasmic reticulum [GO:0005783]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681] | mRNA binding [GO:0003729]; RNA binding [GO:0003723] | 41663.26014388865 | -0.041949474916387 | 0.986307039431929 | 1 |
| Q00839 | Q00839 | HNRPU_HUMAN | Heterogeneous nuclear ribonucleoprotein U (hnRNP U) (GRIP120) (Nuclear p120 ribonucleoprotein) (Scaffold-attachment factor A) (SAF-A) (p120) (pp120) | HNRNPU | adaptive thermogenesis [GO:1990845]; cardiac muscle cell development [GO:0055013]; cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to leukemia inhibitory factor [GO:1990830]; chromatin organization [GO:0006325]; circadian regulation of gene expression [GO:0032922]; CRD-mediated mRNA stabilization [GO:0070934]; dendritic transport of messenger ribonucleoprotein complex [GO:0098963]; dosage compensation by inactivation of X chromosome [GO:0009048]; maintenance of protein location in nucleus [GO:0051457]; mRNA splicing, via spliceosome [GO:0000398]; mRNA stabilization [GO:0048255]; negative regulation of kinase activity [GO:0033673]; negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900152]; negative regulation of stem cell differentiation [GO:2000737]; negative regulation of telomere maintenance via telomerase [GO:0032211]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription elongation by RNA polymerase II [GO:0034244]; osteoblast differentiation [GO:0001649]; positive regulation of attachment of mitotic spindle microtubules to kinetochore [GO:1902425]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cytoplasmic translation [GO:2000767]; positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity [GO:2000373]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein localization to spindle microtubule [GO:1902889]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of chromatin organization [GO:1902275]; regulation of mitotic cell cycle [GO:0007346]; regulation of mitotic spindle assembly [GO:1901673]; RNA localization to chromatin [GO:1990280]; RNA processing [GO:0006396] | catalytic step 2 spliceosome [GO:0071013]; cell surface [GO:0009986]; centrosome [GO:0005813]; CRD-mediated mRNA stability complex [GO:0070937]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; inactive sex chromosome [GO:0098577]; kinetochore [GO:0000776]; membrane [GO:0016020]; midbody [GO:0030496]; mitotic spindle [GO:0072686]; mitotic spindle microtubule [GO:1990498]; mitotic spindle midzone [GO:1990023]; nuclear chromosome [GO:0000228]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]; spindle pole [GO:0000922]; telomerase holoenzyme complex [GO:0005697] | actin binding [GO:0003779]; ATP binding [GO:0005524]; chromatin binding [GO:0003682]; chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; double-stranded DNA binding [GO:0003690]; double-stranded RNA binding [GO:0003725]; identical protein binding [GO:0042802]; lncRNA binding [GO:0106222]; mRNA 3'-UTR binding [GO:0003730]; poly(A) binding [GO:0008143]; poly(C) RNA binding [GO:0017130]; poly(G) binding [GO:0034046]; pre-mRNA binding [GO:0036002]; promoter-specific chromatin binding [GO:1990841]; protein-containing complex binding [GO:0044877]; ribonucleoprotein complex binding [GO:0043021]; RNA binding [GO:0003723]; RNA polymerase II C-terminal domain binding [GO:0099122]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II complex binding [GO:0000993]; sequence-specific double-stranded DNA binding [GO:1990837]; single-stranded DNA binding [GO:0003697]; single-stranded RNA binding [GO:0003727]; snRNA binding [GO:0017069]; telomerase RNA binding [GO:0070034]; TFIIH-class transcription factor complex binding [GO:0001097]; transcription corepressor activity [GO:0003714] | 79625.8062295728 | 0.0135583940517325 | 0.999998922418359 | 1 |
| Q86VS8 | Q86VS8 | HOOK3_HUMAN | Protein Hook homolog 3 (h-hook3) (hHK3) | HOOK3 | cytoplasmic microtubule organization [GO:0031122]; cytoskeleton-dependent intracellular transport [GO:0030705]; early endosome to late endosome transport [GO:0045022]; endosome organization [GO:0007032]; endosome to lysosome transport [GO:0008333]; Golgi localization [GO:0051645]; interkinetic nuclear migration [GO:0022027]; lysosome organization [GO:0007040]; microtubule anchoring at centrosome [GO:0034454]; negative regulation of neurogenesis [GO:0050768]; neuronal stem cell population maintenance [GO:0097150]; protein localization to centrosome [GO:0071539]; protein localization to perinuclear region of cytoplasm [GO:1905719]; protein transport [GO:0015031] | centriolar satellite [GO:0034451]; centrosome [GO:0005813]; cis-Golgi network [GO:0005801]; cytoplasm [GO:0005737]; FHF complex [GO:0070695]; microtubule [GO:0005874]; pericentriolar material [GO:0000242] | dynactin binding [GO:0034452]; dynein intermediate chain binding [GO:0045505]; dynein light chain binding [GO:0045503]; dynein light intermediate chain binding [GO:0051959]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017] | 23246.380155404848 | -0.0662290084077899 | 0.965212996082342 | 1 |
| Q969F9 | Q969F9 | HPS3_HUMAN | BLOC-2 complex member HPS3 (Hermansky-Pudlak syndrome 3 protein) | HPS3 | intracellular transport [GO:0046907]; melanosome assembly [GO:1903232]; organelle organization [GO:0006996]; platelet dense granule organization [GO:0060155] | BLOC-2 complex [GO:0031084]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769] | 3401.585779031325 | -0.431189821540782 | 0.660215199439383 | 1 | |
| P01112 | P01112 | RASH_HUMAN | GTPase HRas (EC 3.6.5.2) (H-Ras-1) (Ha-Ras) (Transforming protein p21) (c-H-ras) (p21ras) [Cleaved into: GTPase HRas, N-terminally processed] | HRAS | adipose tissue development [GO:0060612]; animal organ morphogenesis [GO:0009887]; cell surface receptor signaling pathway [GO:0007166]; cellular response to gamma radiation [GO:0071480]; cellular senescence [GO:0090398]; chemotaxis [GO:0006935]; defense response to protozoan [GO:0042832]; endocytosis [GO:0006897]; fibroblast proliferation [GO:0048144]; insulin receptor signaling pathway [GO:0008286]; intrinsic apoptotic signaling pathway [GO:0097193]; MAPK cascade [GO:0000165]; myelination [GO:0042552]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of neuron apoptotic process [GO:0043524]; neuron apoptotic process [GO:0051402]; oncogene-induced cell senescence [GO:0090402]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of GTPase activity [GO:0043547]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of ruffle assembly [GO:1900029]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type II interferon production [GO:0032729]; positive regulation of wound healing [GO:0090303]; Ras protein signal transduction [GO:0007265]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell cycle [GO:0051726]; regulation of cell population proliferation [GO:0042127]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; regulation of transcription by RNA polymerase II [GO:0006357]; Schwann cell development [GO:0014044]; signal transduction [GO:0007165]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; GTPase complex [GO:1905360]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886] | G protein activity [GO:0003925]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein-membrane adaptor activity [GO:0043495] | 84476.14579024256 | -0.0367948976984568 | 0.996008359073601 | 1 |
| Q53T59 | Q53T59 | H1BP3_HUMAN | HCLS1-binding protein 3 (HS1-binding protein 3) (HSP1BP-3) | HS1BP3 | regulation of apoptotic process [GO:0042981] | endoplasmic reticulum [GO:0005783]; mitochondrion [GO:0005739] | phosphatidylinositol binding [GO:0035091] | 16856.51549301655 | 0.161982175383394 | 0.725539495746168 | 1 |
| P51659 | P51659 | DHB4_HUMAN | Peroxisomal multifunctional enzyme type 2 (MFE-2) (17-beta-hydroxysteroid dehydrogenase 4) (17-beta-HSD 4) (D-bifunctional protein) (DBP) (Multifunctional protein 2) (MFP-2) (Short chain dehydrogenase/reductase family 8C member 1) [Cleaved into: (3R)-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.n12); Enoyl-CoA hydratase 2 (EC 4.2.1.107) (EC 4.2.1.119) (3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase)] | HSD17B4 | androgen metabolic process [GO:0008209]; estrogen metabolic process [GO:0008210]; fatty acid beta-oxidation [GO:0006635]; medium-chain fatty-acyl-CoA metabolic process [GO:0036112]; osteoblast differentiation [GO:0001649]; Sertoli cell development [GO:0060009]; very long-chain fatty acid metabolic process [GO:0000038]; very long-chain fatty-acyl-CoA metabolic process [GO:0036111] | cytosol [GO:0005829]; membrane [GO:0016020]; peroxisomal matrix [GO:0005782]; peroxisomal membrane [GO:0005778]; peroxisome [GO:0005777] | (3R)-hydroxyacyl-CoA dehydrogenase (NAD) activity [GO:0106386]; 17-beta-hydroxysteroid dehydrogenase (NAD+) activity [GO:0044594]; 3-hydroxyacyl-CoA dehydratase activity [GO:0018812]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity [GO:0033989]; enoyl-CoA hydratase activity [GO:0004300]; estradiol 17-beta-dehydrogenase [NAD(P)] activity [GO:0004303]; isomerase activity [GO:0016853]; protein homodimerization activity [GO:0042803] | 38287.6492711241 | 0.0341346003642425 | 0.843706017700313 | 1 |
| Q58FF6 | Q58FF6 | H90B4_HUMAN | Putative heat shock protein HSP 90-beta 4 | HSP90AB4P | cellular response to heat [GO:0034605]; protein folding [GO:0006457]; protein stabilization [GO:0050821] | cytosol [GO:0005829]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991] | ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-dependent protein folding chaperone [GO:0140662]; disordered domain specific binding [GO:0097718]; unfolded protein binding [GO:0051082] | 24030.7259429136 | 0.284771530863191 | 0.81325323822944 | 1 |
| O43301 | O43301 | HS12A_HUMAN | Heat shock 70 kDa protein 12A (Heat shock protein family A member 12A) | HSPA12A | cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; nucleus [GO:0005634] | ATP binding [GO:0005524] | 6331.28990511525 | -0.055972758296798 | 0.996984430400292 | 1 | |
| P48723 | P48723 | HSP13_HUMAN | Heat shock 70 kDa protein 13 (Heat shock protein family A member 13) (Microsomal stress-70 protein ATPase core) (Stress-70 protein chaperone microsome-associated 60 kDa protein) | HSPA13 | chaperone cofactor-dependent protein refolding [GO:0051085]; protein refolding [GO:0042026] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; intracellular membrane-bounded organelle [GO:0043231]; nucleus [GO:0005634]; plasma membrane [GO:0005886] | ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-dependent protein folding chaperone [GO:0140662]; heat shock protein binding [GO:0031072]; protein folding chaperone [GO:0044183] | 23372.98645751945 | -0.0582423769719738 | 0.98226633133294 | 1 |
| P34932 | P34932 | HSP74_HUMAN | Heat shock 70 kDa protein 4 (HSP70RY) (Heat shock 70-related protein APG-2) (Heat shock protein family H member 2) | HSPA4 | chaperone-mediated protein complex assembly [GO:0051131]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; response to unfolded protein [GO:0006986] | cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]; nucleus [GO:0005634] | adenyl-nucleotide exchange factor activity [GO:0000774]; ATP binding [GO:0005524]; ATP-dependent protein folding chaperone [GO:0140662] | 57870.519707286105 | 0.101232339986821 | 0.825307387711178 | 1 |
| O95757 | O95757 | HS74L_HUMAN | Heat shock 70 kDa protein 4L (Heat shock 70-related protein APG-1) (Heat shock protein family H member 3) (Heat-shock protein family A member 4-like protein) (HSPA4-like protein) (Osmotic stress protein 94) | HSPA4L | protein folding [GO:0006457]; response to unfolded protein [GO:0006986] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634] | adenyl-nucleotide exchange factor activity [GO:0000774]; ATP binding [GO:0005524]; ATP-dependent protein folding chaperone [GO:0140662] | 19541.092812118397 | -0.0359879193349988 | 0.963244208608842 | 1 |
| P04792 | P04792 | HSPB1_HUMAN | Heat shock protein beta-1 (HspB1) (28 kDa heat shock protein) (Estrogen-regulated 24 kDa protein) (Heat shock 27 kDa protein) (HSP 27) (Heat shock protein family B member 1) (Stress-responsive protein 27) (SRP27) | HSPB1 | anterograde axonal protein transport [GO:0099641]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; chaperone-mediated protein folding [GO:0061077]; intracellular signal transduction [GO:0035556]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of protein kinase activity [GO:0006469]; platelet aggregation [GO:0070527]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of tumor necrosis factor production [GO:0032760]; protein refolding [GO:0042026]; regulation of autophagy [GO:0010506]; regulation of canonical NF-kappaB signal transduction [GO:0043122]; regulation of protein phosphorylation [GO:0001932]; regulation of translational initiation [GO:0006446]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; response to virus [GO:0009615]; vascular endothelial growth factor receptor signaling pathway [GO:0048010] | axon cytoplasm [GO:1904115]; cornified envelope [GO:0001533]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; spindle [GO:0005819]; Z disc [GO:0030018] | identical protein binding [GO:0042802]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein kinase C binding [GO:0005080]; protein kinase C inhibitor activity [GO:0008426]; RNA binding [GO:0003723]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; ubiquitin binding [GO:0043130]; unfolded protein binding [GO:0051082] | 794202.509545211 | 0.124359797865879 | 0.852744125732366 | 1 |
| Q9NZL4 | Q9NZL4 | HPBP1_HUMAN | Hsp70-binding protein 1 (HspBP1) (Heat shock protein-binding protein 1) (Hsp70-binding protein 2) (HspBP2) (Hsp70-interacting protein 1) (Hsp70-interacting protein 2) | HSPBP1 | positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein ubiquitination [GO:0031398]; protein folding [GO:0006457] | endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615] | adenyl-nucleotide exchange factor activity [GO:0000774]; enzyme inhibitor activity [GO:0004857]; molecular sequestering activity [GO:0140313]; ubiquitin protein ligase binding [GO:0031625] | 14278.86270044425 | 0.0343044232091534 | 0.986691708752368 | 1 |
| Q9BUP3 | Q9BUP3 | HTAI2_HUMAN | Oxidoreductase HTATIP2 (EC 1.1.1.-) (30 kDa HIV-1 TAT-interacting protein) (HIV-1 TAT-interactive protein 2) | HTATIP2 | angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; cell differentiation [GO:0030154]; import into nucleus [GO:0051170]; negative regulation of apoptotic process [GO:0043066]; positive regulation of programmed cell death [GO:0043068]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein autophosphorylation [GO:0046777]; regulation of angiogenesis [GO:0045765]; regulation of transcription by RNA polymerase II [GO:0006357] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; nuclear envelope [GO:0005635]; nucleus [GO:0005634] | oxidoreductase activity [GO:0016491]; protein serine/threonine kinase activity [GO:0004674]; transcription coactivator activity [GO:0003713] | 15429.3040061166 | -0.0129875344080105 | 0.998097230811627 | 1 |
| O43464 | O43464 | HTRA2_HUMAN | Serine protease HTRA2, mitochondrial (EC 3.4.21.108) (High temperature requirement protein A2) (HtrA2) (Omi stress-regulated endoprotease) (Serine protease 25) (Serine proteinase OMI) | HTRA2 | adult walking behavior [GO:0007628]; cellular response to growth factor stimulus [GO:0071363]; cellular response to heat [GO:0034605]; cellular response to interferon-beta [GO:0035458]; cellular response to oxidative stress [GO:0034599]; cellular response to retinoic acid [GO:0071300]; ceramide metabolic process [GO:0006672]; execution phase of apoptosis [GO:0097194]; forebrain development [GO:0030900]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; mitochondrial protein catabolic process [GO:0035694]; negative regulation of cell cycle [GO:0045786]; negative regulation of mitophagy in response to mitochondrial depolarization [GO:1904924]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; neuron apoptotic process [GO:0051402]; neuron development [GO:0048666]; pentacyclic triterpenoid metabolic process [GO:0019742]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; positive regulation of mitochondrion organization [GO:0010822]; positive regulation of protein targeting to mitochondrion [GO:1903955]; programmed cell death [GO:0012501]; protein autoprocessing [GO:0016540]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of autophagy of mitochondrion [GO:1903146]; regulation of multicellular organism growth [GO:0040014]; response to herbicide [GO:0009635] | CD40 receptor complex [GO:0035631]; chromatin [GO:0000785]; cytoplasmic side of plasma membrane [GO:0009898]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; mitochondrial intermembrane space [GO:0005758]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; serine-type endopeptidase complex [GO:1905370] | identical protein binding [GO:0042802]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; unfolded protein binding [GO:0051082] | 9121.81209516308 | 0.0554819860701479 | 0.952661976146089 | 1 |
| P42858 | P42858 | HD_HUMAN | Huntingtin (Huntington disease protein) (HD protein) [Cleaved into: Huntingtin, myristoylated N-terminal fragment] | HTT | apoptotic process [GO:0006915]; establishment of mitotic spindle orientation [GO:0000132]; Golgi organization [GO:0007030]; microtubule-based transport [GO:0099111]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; positive regulation of aggrephagy [GO:1905337]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cilium assembly [GO:0045724]; positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [GO:0031587]; positive regulation of lipophagy [GO:1904504]; positive regulation of mitophagy [GO:1901526]; protein destabilization [GO:0031648]; regulation of CAMKK-AMPK signaling cascade [GO:1905289]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of phosphoprotein phosphatase activity [GO:0043666]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; vesicle transport along microtubule [GO:0047496]; vocal learning [GO:0042297] | autophagosome [GO:0005776]; axon [GO:0030424]; centriole [GO:0005814]; cytoplasm [GO:0005737]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; inclusion body [GO:0016234]; late endosome [GO:0005770]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; protein-containing complex [GO:0032991] | beta-tubulin binding [GO:0048487]; dynactin binding [GO:0034452]; dynein intermediate chain binding [GO:0045505]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; p53 binding [GO:0002039]; profilin binding [GO:0005522]; transmembrane transporter binding [GO:0044325] | 2937.068650969545 | -0.0715091659623001 | 0.99887716599925 | 1 |
| Q9NSE4 | Q9NSE4 | SYIM_HUMAN | Isoleucine--tRNA ligase, mitochondrial (EC 6.1.1.5) (Isoleucyl-tRNA synthetase) (IleRS) | IARS2 | isoleucyl-tRNA aminoacylation [GO:0006428]; mitochondrial translation [GO:0032543]; tRNA aminoacylation for protein translation [GO:0006418] | cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739] | aminoacyl-tRNA editing activity [GO:0002161]; ATP binding [GO:0005524]; isoleucine-tRNA ligase activity [GO:0004822]; tRNA binding [GO:0000049] | 16047.398997835851 | 0.120852392237449 | 0.986022755674176 | 1 |
| P14735 | P14735 | IDE_HUMAN | Insulin-degrading enzyme (EC 3.4.24.56) (Abeta-degrading protease) (Insulin protease) (Insulinase) (Insulysin) | IDE | amyloid-beta clearance [GO:0097242]; amyloid-beta clearance by cellular catabolic process [GO:0150094]; amyloid-beta metabolic process [GO:0050435]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; bradykinin catabolic process [GO:0010815]; hormone catabolic process [GO:0042447]; insulin catabolic process [GO:1901143]; insulin metabolic process [GO:1901142]; insulin receptor signaling pathway [GO:0008286]; peptide catabolic process [GO:0043171]; positive regulation of protein binding [GO:0032092]; positive regulation of protein catabolic process [GO:0045732]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; proteolysis involved in protein catabolic process [GO:0051603]; regulation of aerobic respiration [GO:1903715]; ubiquitin recycling [GO:0010992] | basolateral plasma membrane [GO:0016323]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777] | ATP binding [GO:0005524]; endopeptidase activity [GO:0004175]; identical protein binding [GO:0042802]; insulin binding [GO:0043559]; metalloendopeptidase activity [GO:0004222]; peptide binding [GO:0042277]; protein homodimerization activity [GO:0042803]; ubiquitin-dependent protein binding [GO:0140036]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270] | 8780.72376377541 | -0.0164845488649373 | 0.999999687162524 | 1 |
| P35475 | P35475 | IDUA_HUMAN | Alpha-L-iduronidase (EC 3.2.1.76) | IDUA | dermatan sulfate catabolic process [GO:0030209]; disaccharide metabolic process [GO:0005984]; glycosaminoglycan catabolic process [GO:0006027]; heparan sulfate proteoglycan catabolic process [GO:0030200]; heparin catabolic process [GO:0030211] | extracellular exosome [GO:0070062]; lysosomal lumen [GO:0043202] | L-iduronidase activity [GO:0003940]; signaling receptor binding [GO:0005102] | 22788.0003275665 | 0.074049573326665 | 0.974509166991819 | 1 |
| Q9BW83 | Q9BW83 | IFT27_HUMAN | Intraflagellar transport protein 27 homolog (Putative GTP-binding protein RAY-like) (Rab-like protein 4) | IFT27 | cilium assembly [GO:0060271]; cochlea development [GO:0090102]; inner ear receptor cell stereocilium organization [GO:0060122]; intracellular protein transport [GO:0006886]; intraciliary anterograde transport [GO:0035720]; intraciliary transport [GO:0042073]; kidney development [GO:0001822]; smoothened signaling pathway [GO:0007224]; spermatogenesis [GO:0007283]; vesicle-mediated transport [GO:0016192] | centrosome [GO:0005813]; ciliary tip [GO:0097542]; cilium [GO:0005929]; cytoplasm [GO:0005737]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; intraciliary transport particle B [GO:0030992]; motile cilium [GO:0031514]; nucleus [GO:0005634]; sperm flagellum [GO:0036126]; sperm midpiece [GO:0097225]; sperm principal piece [GO:0097228] | GTP binding [GO:0005525]; GTPase activity [GO:0003924] | 14824.72357500595 | -0.0244530192081939 | 0.996548894529047 | 1 |
| Q9NZI8 | Q9NZI8 | IF2B1_HUMAN | Insulin-like growth factor 2 mRNA-binding protein 1 (IGF2 mRNA-binding protein 1) (IMP-1) (IMP1) (Coding region determinant-binding protein) (CRD-BP) (IGF-II mRNA-binding protein 1) (VICKZ family member 1) (Zipcode-binding protein 1) (ZBP-1) | IGF2BP1 | CRD-mediated mRNA stabilization [GO:0070934]; dendrite arborization [GO:0140059]; mRNA transport [GO:0051028]; negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900152]; negative regulation of translation [GO:0017148]; nervous system development [GO:0007399]; neuronal stem cell population maintenance [GO:0097150]; pallium cell proliferation in forebrain [GO:0022013]; positive regulation of cytoplasmic translation [GO:2000767]; regulation of cytokine production [GO:0001817]; regulation of gene expression [GO:0010468]; regulation of mRNA stability involved in response to stress [GO:0010610] | CRD-mediated mRNA stability complex [GO:0070937]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; filopodium [GO:0030175]; growth cone [GO:0030426]; lamellipodium [GO:0030027]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]; perinuclear region of cytoplasm [GO:0048471]; ribonucleoprotein complex [GO:1990904] | mRNA 3'-UTR binding [GO:0003730]; mRNA 5'-UTR binding [GO:0048027]; mRNA binding [GO:0003729]; N6-methyladenosine-containing RNA reader activity [GO:1990247]; RNA binding [GO:0003723]; translation regulator activity [GO:0045182] | 4014.45580545719 | 0.138835770639882 | 0.82834049986161 | 1 |
| Q9Y6M1 | Q9Y6M1 | IF2B2_HUMAN | Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2 mRNA-binding protein 2) (IMP-2) (Hepatocellular carcinoma autoantigen p62) (IGF-II mRNA-binding protein 2) (VICKZ family member 2) | IGF2BP2 | anatomical structure morphogenesis [GO:0009653]; cold-induced thermogenesis [GO:0106106]; CRD-mediated mRNA stabilization [GO:0070934]; energy homeostasis [GO:0097009]; mRNA transport [GO:0051028]; negative regulation of translation [GO:0017148]; nervous system development [GO:0007399]; regulation of cytokine production [GO:0001817]; regulation of gene expression [GO:0010468] | cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; nucleus [GO:0005634]; P-body [GO:0000932] | mRNA 3'-UTR binding [GO:0003730]; mRNA 5'-UTR binding [GO:0048027]; N6-methyladenosine-containing RNA reader activity [GO:1990247]; RNA binding [GO:0003723]; translation regulator activity [GO:0045182]; translation regulator activity, nucleic acid binding [GO:0090079] | 52685.0464638329 | -0.0773207966286096 | 0.854968278900672 | 1 |
| O00425 | O00425 | IF2B3_HUMAN | Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2 mRNA-binding protein 3) (IMP-3) (IGF-II mRNA-binding protein 3) (KH domain-containing protein overexpressed in cancer) (hKOC) (VICKZ family member 3) | IGF2BP3 | anatomical structure morphogenesis [GO:0009653]; CRD-mediated mRNA stabilization [GO:0070934]; mRNA transport [GO:0051028]; negative regulation of translation [GO:0017148]; nervous system development [GO:0007399]; regulation of cytokine production [GO:0001817]; regulation of gene expression [GO:0010468]; translation [GO:0006412] | cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; nucleus [GO:0005634]; P-body [GO:0000932] | mRNA 3'-UTR binding [GO:0003730]; mRNA 5'-UTR binding [GO:0048027]; N6-methyladenosine-containing RNA reader activity [GO:1990247]; RNA binding [GO:0003723]; translation regulator activity [GO:0045182] | 44663.5230152196 | -0.0399179124045379 | 0.915231835777408 | 1 |
| Q12905 | Q12905 | ILF2_HUMAN | Interleukin enhancer-binding factor 2 (Nuclear factor of activated T-cells 45 kDa) | ILF2 | positive regulation of DNA-templated transcription [GO:0045893] | catalytic step 2 spliceosome [GO:0071013]; cytosol [GO:0005829]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724] | DNA binding [GO:0003677]; double-stranded RNA binding [GO:0003725]; RNA binding [GO:0003723] | 58034.995327947254 | -0.0507886210054098 | 0.999497171506513 | 1 |
| Q16891 | Q16891 | MIC60_HUMAN | MICOS complex subunit MIC60 (Cell proliferation-inducing gene 4/52 protein) (Mitochondrial inner membrane protein) (Mitofilin) (p87/89) | IMMT | cristae formation [GO:0042407]; inner mitochondrial membrane organization [GO:0007007]; mitochondrial calcium ion homeostasis [GO:0051560]; neuron cellular homeostasis [GO:0070050] | membrane [GO:0016020]; MIB complex [GO:0140275]; MICOS complex [GO:0061617]; mitochondrial crista junction [GO:0044284]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; SAM complex [GO:0001401] | RNA binding [GO:0003723] | 56018.416645120495 | -0.030119394101745 | 0.999835646651185 | 1 |
| Q96G21 | Q96G21 | IMP4_HUMAN | U3 small nucleolar ribonucleoprotein protein IMP4 (U3 snoRNP protein IMP4) (Brix domain-containing protein 4) | IMP4 | maturation of SSU-rRNA [GO:0030490]; ribosomal small subunit biogenesis [GO:0042274]; rRNA processing [GO:0006364] | fibrillar center [GO:0001650]; Mpp10 complex [GO:0034457]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; preribosome [GO:0030684]; small-subunit processome [GO:0032040] | rRNA primary transcript binding [GO:0042134]; snoRNA binding [GO:0030515] | 9094.22156663064 | 0.131536596295808 | 0.817837364928404 | 1 |
| P12268 | P12268 | IMDH2_HUMAN | Inosine-5'-monophosphate dehydrogenase 2 (IMP dehydrogenase 2) (IMPD 2) (IMPDH 2) (EC 1.1.1.205) (Inosine-5'-monophosphate dehydrogenase type II) (IMP dehydrogenase II) (IMPDH-II) | IMPDH2 | 'de novo' XMP biosynthetic process [GO:0097294]; cellular response to interleukin-4 [GO:0071353]; circadian rhythm [GO:0007623]; GMP biosynthetic process [GO:0006177]; GTP biosynthetic process [GO:0006183]; lymphocyte proliferation [GO:0046651] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; membrane [GO:0016020]; nucleus [GO:0005634]; peroxisomal membrane [GO:0005778]; secretory granule lumen [GO:0034774] | DNA binding [GO:0003677]; IMP dehydrogenase activity [GO:0003938]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; RNA binding [GO:0003723] | 34653.0713736591 | -0.101597249301683 | 0.872661085224542 | 1 |
| P49441 | P49441 | INPP_HUMAN | Inositol polyphosphate 1-phosphatase (IPP) (IPPase) (EC 3.1.3.57) | INPP1 | phosphate-containing compound metabolic process [GO:0006796]; phosphatidylinositol phosphate biosynthetic process [GO:0046854]; signal transduction [GO:0007165] | cytosol [GO:0005829] | inositol-1,3,4-trisphosphate 1-phosphatase activity [GO:0052829]; inositol-1,4-bisphosphate 1-phosphatase activity [GO:0004441]; metal ion binding [GO:0046872] | 6533.235610835534 | -0.262014164370803 | 0.912963942949281 | 1 |
| Q96PE3 | Q96PE3 | INP4A_HUMAN | Inositol polyphosphate-4-phosphatase type I A (Inositol polyphosphate 4-phosphatase type I) (Type I inositol 3,4-bisphosphate 4-phosphatase) (EC 3.1.3.66) | INPP4A | inositol phosphate metabolic process [GO:0043647]; phosphatidylinositol biosynthetic process [GO:0006661]; signal transduction [GO:0007165] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome membrane [GO:0031901]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; recycling endosome membrane [GO:0055038] | inositol-1,3,4-trisphosphate 4-phosphatase activity [GO:0017161]; inositol-3,4-bisphosphate 4-phosphatase activity [GO:0052828]; phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity [GO:0016316] | 7621.995042321905 | 0.0608948360037848 | 0.90349588370515 | 1 |
| Q14642 | Q14642 | I5P1_HUMAN | Inositol polyphosphate-5-phosphatase A (EC 3.1.3.56) (43 kDa inositol polyphosphate 5-phosphatase) (Type I inositol 1,4,5-trisphosphate 5-phosphatase) (5PTase) | INPP5A | inositol phosphate metabolic process [GO:0043647]; negative regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900737]; phosphatidylinositol dephosphorylation [GO:0046856] | dendrite [GO:0030425]; membrane [GO:0016020]; plasma membrane [GO:0005886] | inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity [GO:0052659]; inositol-1,4,5-trisphosphate 5-phosphatase activity [GO:0052658]; inositol-polyphosphate 5-phosphatase activity [GO:0004445]; PH domain binding [GO:0042731] | 4925.343396252375 | 0.0510320342178611 | 0.99443357838551 | 1 |
| Q8N201 | Q8N201 | INT1_HUMAN | Integrator complex subunit 1 (Int1) | INTS1 | embryo implantation [GO:0007566]; inner cell mass cell proliferation [GO:0001833]; negative regulation of apoptotic process [GO:0043066]; regulation of transcription elongation by RNA polymerase II [GO:0034243]; snRNA processing [GO:0016180]; U2 snRNA 3'-end processing [GO:0034474] | integrator complex [GO:0032039]; membrane [GO:0016020]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] | 1814.9580556548199 | 0.556588908947246 | 0.809198680612241 | 1 | |
| Q96CB8 | Q96CB8 | INT12_HUMAN | Integrator complex subunit 12 (Int12) (PHD finger protein 22) | INTS12 | regulation of transcription elongation by RNA polymerase II [GO:0034243]; snRNA 3'-end processing [GO:0034472]; snRNA processing [GO:0016180] | integrator complex [GO:0032039]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] | metal ion binding [GO:0046872] | 4019.28163372707 | -0.136926615832677 | 0.713724765672084 | 1 |
| Q68E01 | Q68E01 | INT3_HUMAN | Integrator complex subunit 3 (Int3) (SOSS complex subunit A) (Sensor of single-strand DNA complex subunit A) (SOSS-A) (Sensor of ssDNA subunit A) | INTS3 | DNA damage response [GO:0006974]; DNA repair [GO:0006281]; double-strand break repair via homologous recombination [GO:0000724]; mitotic G2/M transition checkpoint [GO:0044818]; regulation of transcription elongation by RNA polymerase II [GO:0034243]; response to ionizing radiation [GO:0010212]; snRNA processing [GO:0016180] | cytoplasm [GO:0005737]; integrator complex [GO:0032039]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; site of double-strand break [GO:0035861]; SOSS complex [GO:0070876] | 2790.080563017205 | -0.283307849802691 | 0.758269367791153 | 1 | |
| Q92551 | Q92551 | IP6K1_HUMAN | Inositol hexakisphosphate kinase 1 (InsP6 kinase 1) (EC 2.7.4.21) (Inositol hexaphosphate kinase 1) | IP6K1 | inositol phosphate biosynthetic process [GO:0032958]; inositol phosphate metabolic process [GO:0043647]; negative regulation of cold-induced thermogenesis [GO:0120163]; phosphatidylinositol phosphate biosynthetic process [GO:0046854]; phosphorylation [GO:0016310] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; fibrillar center [GO:0001650]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] | ATP binding [GO:0005524]; inositol 5-diphosphate pentakisphosphate 5-kinase activity [GO:0052836]; inositol diphosphate tetrakisphosphate kinase activity [GO:0052839]; inositol heptakisphosphate kinase activity [GO:0000829]; inositol hexakisphosphate 1-kinase activity [GO:0052723]; inositol hexakisphosphate 3-kinase activity [GO:0052724]; inositol hexakisphosphate 5-kinase activity [GO:0000832]; inositol hexakisphosphate kinase activity [GO:0000828]; inositol-1,3,4,5,6-pentakisphosphate kinase activity [GO:0000827] | 1859.649129419495 | 0.0226150228640959 | 0.970391003245037 | 1 |
| Q9UI26 | Q9UI26 | IPO11_HUMAN | Importin-11 (Imp11) (Ran-binding protein 11) (RanBP11) | IPO11 | protein import into nucleus [GO:0006606]; ribosomal protein import into nucleus [GO:0006610] | cytosol [GO:0005829]; nuclear envelope [GO:0005635]; nucleoplasm [GO:0005654] | nuclear import signal receptor activity [GO:0061608]; small GTPase binding [GO:0031267] | 4021.9824520176003 | 0.0470477451961441 | 0.999958341172053 | 1 |
| O94829 | O94829 | IPO13_HUMAN | Importin-13 (Imp13) (Karyopherin-13) (Kap13) (Ran-binding protein 13) (RanBP13) | IPO13 | protein import into nucleus [GO:0006606] | cytoplasm [GO:0005737]; nucleus [GO:0005634] | small GTPase binding [GO:0031267] | 5888.28851742533 | -0.227068807562249 | 0.742953033592455 | 1 |
| Q8TEX9 | Q8TEX9 | IPO4_HUMAN | Importin-4 (Imp4) (Importin-4b) (Imp4b) (Ran-binding protein 4) (RanBP4) | IPO4 | protein import into nucleus [GO:0006606]; protein localization to nucleus [GO:0034504] | chromatin [GO:0000785]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleus [GO:0005634]; protein-containing complex [GO:0032991] | nuclear import signal receptor activity [GO:0061608]; nuclear localization sequence binding [GO:0008139]; small GTPase binding [GO:0031267] | 9753.65361385723 | -0.176618944742912 | 0.831615603005665 | 1 |
| O00410 | O00410 | IPO5_HUMAN | Importin-5 (Imp5) (Importin subunit beta-3) (Karyopherin beta-3) (Ran-binding protein 5) (RanBP5) | IPO5 | cellular response to amino acid stimulus [GO:0071230]; cytoplasmic pattern recognition receptor signaling pathway [GO:0002753]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; NLS-bearing protein import into nucleus [GO:0006607]; positive regulation of protein import into nucleus [GO:0042307]; protein import into nucleus [GO:0006606]; ribosomal protein import into nucleus [GO:0006610] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] | GTPase inhibitor activity [GO:0005095]; nuclear import signal receptor activity [GO:0061608]; nuclear localization sequence binding [GO:0008139]; RNA binding [GO:0003723]; small GTPase binding [GO:0031267] | 26545.7327610623 | -0.0679439989109009 | 0.999999999560544 | 1 |
| O15397 | O15397 | IPO8_HUMAN | Importin-8 (Imp8) (Ran-binding protein 8) (RanBP8) | IPO8 | protein import into nucleus [GO:0006606]; signal transduction [GO:0007165] | cytosol [GO:0005829]; nuclear envelope [GO:0005635]; nucleoplasm [GO:0005654] | small GTPase binding [GO:0031267] | 7406.07177945875 | 0.126076328256983 | 0.75649059359979 | 1 |
| Q96P70 | Q96P70 | IPO9_HUMAN | Importin-9 (Imp9) (Ran-binding protein 9) (RanBP9) | IPO9 | proteasome localization [GO:0031144]; protein import into nucleus [GO:0006606] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; nuclear envelope [GO:0005635] | histone binding [GO:0042393]; histone chaperone activity [GO:0140713]; nuclear import signal receptor activity [GO:0061608]; small GTPase binding [GO:0031267] | 7351.62761979035 | 3.19549215071668E-4 | 0.99999999879096 | 1 |
| Q7Z5L9 | Q7Z5L9 | I2BP2_HUMAN | Interferon regulatory factor 2-binding protein 2 (IRF-2-binding protein 2) (IRF-2BP2) | IRF2BP2 | immature B cell differentiation [GO:0002327]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357] | cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] | metal ion binding [GO:0046872]; transcription corepressor activity [GO:0003714] | 14055.5999191587 | 0.0217821162894648 | 0.999397351136316 | 1 |
| Q14653 | Q14653 | IRF3_HUMAN | Interferon regulatory factor 3 (IRF-3) | IRF3 | antiviral innate immune response [GO:0140374]; apoptotic process [GO:0006915]; cellular response to exogenous dsRNA [GO:0071360]; cellular response to virus [GO:0098586]; cGAS/STING signaling pathway [GO:0140896]; cytoplasmic pattern recognition receptor signaling pathway [GO:0002753]; defense response to virus [GO:0051607]; DNA damage response [GO:0006974]; immune system process [GO:0002376]; innate immune response [GO:0045087]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; macrophage apoptotic process [GO:0071888]; MDA-5 signaling pathway [GO:0039530]; mRNA transcription [GO:0009299]; positive regulation of canonical NF-kappaB signal transduction [GO:0043123]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; programmed necrotic cell death [GO:0097300]; regulation of apoptotic process [GO:0042981]; regulation of inflammatory response [GO:0050727]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction involved in regulation of gene expression [GO:0023019]; toll-like receptor 4 signaling pathway [GO:0034142]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; type I interferon-mediated signaling pathway [GO:0060337] | chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] | DNA binding [GO:0003677]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; identical protein binding [GO:0042802]; promoter-specific chromatin binding [GO:1990841]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; sequence-specific double-stranded DNA binding [GO:1990837] | 12569.22870295495 | 0.0470997607505537 | 0.763046210313148 | 1 |
| Q9ULR0 | Q9ULR0 | ISY1_HUMAN | Pre-mRNA-splicing factor ISY1 homolog | ISY1 | generation of catalytic spliceosome for second transesterification step [GO:0000350]; mRNA 3'-splice site recognition [GO:0000389]; mRNA splicing, via spliceosome [GO:0000398] | catalytic step 2 spliceosome [GO:0071013]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; post-mRNA release spliceosomal complex [GO:0071014]; post-spliceosomal complex [GO:0071020]; Prp19 complex [GO:0000974]; U2-type catalytic step 1 spliceosome [GO:0071006] | RNA binding [GO:0003723] | 8067.824395954611 | -0.0320393425716431 | 0.961695661630529 | 1 |
| Q96J02 | Q96J02 | ITCH_HUMAN | E3 ubiquitin-protein ligase Itchy homolog (Itch) (EC 2.3.2.26) (Atrophin-1-interacting protein 4) (AIP4) (HECT-type E3 ubiquitin transferase Itchy homolog) (NFE2-associated polypeptide 1) (NAPP1) | ITCH | apoptotic process [GO:0006915]; CD4-positive, alpha-beta T cell proliferation [GO:0035739]; defense response to virus [GO:0051607]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of apoptotic process [GO:0043066]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of cytoplasmic pattern recognition receptor signaling pathway [GO:0039532]; negative regulation of defense response to virus [GO:0050687]; negative regulation of JNK cascade [GO:0046329]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of type I interferon production [GO:0032480]; nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [GO:0035872]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of receptor catabolic process [GO:2000646]; positive regulation of T cell anergy [GO:0002669]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein K29-linked ubiquitination [GO:0035519]; protein K48-linked ubiquitination [GO:0070936]; protein K63-linked ubiquitination [GO:0070534]; protein monoubiquitination [GO:0006513]; protein ubiquitination [GO:0016567]; receptor internalization [GO:0031623]; regulation of cell growth [GO:0001558]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of necroptotic process [GO:0060544]; regulation of protein deubiquitination [GO:0090085]; symbiont entry into host cell [GO:0046718]; T cell anergy [GO:0002870]; ubiquitin-dependent protein catabolic process [GO:0006511] | cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; early endosome membrane [GO:0031901]; extracellular exosome [GO:0070062]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991] | arrestin family protein binding [GO:1990763]; CXCR chemokine receptor binding [GO:0045236]; ligase activity [GO:0016874]; ribonucleoprotein complex binding [GO:0043021]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-like protein transferase activity [GO:0019787]; ubiquitin-protein transferase activity [GO:0004842] | 7651.22413115382 | 0.0655703536451429 | 0.999345738932484 | 1 |
| P26006 | P26006 | ITA3_HUMAN | Integrin alpha-3 (CD49 antigen-like family member C) (FRP-2) (Galactoprotein B3) (GAPB3) (VLA-3 subunit alpha) (CD antigen CD49c) [Cleaved into: Integrin alpha-3 heavy chain; Integrin alpha-3 light chain] | ITGA3 | cell adhesion mediated by integrin [GO:0033627]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; dendritic spine maintenance [GO:0097062]; exploration behavior [GO:0035640]; heart development [GO:0007507]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; lung development [GO:0030324]; maternal process involved in female pregnancy [GO:0060135]; memory [GO:0007613]; mesodermal cell differentiation [GO:0048333]; negative regulation of cell projection organization [GO:0031345]; negative regulation of Rho protein signal transduction [GO:0035024]; nephron development [GO:0072006]; neuron migration [GO:0001764]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein localization to plasma membrane [GO:1903078]; regulation of BMP signaling pathway [GO:0030510]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015]; regulation of Wnt signaling pathway [GO:0030111]; renal filtration [GO:0097205]; response to gonadotropin [GO:0034698]; response to xenobiotic stimulus [GO:0009410]; Rho protein signal transduction [GO:0007266]; skin development [GO:0043588]; synaptic membrane adhesion [GO:0099560] | basolateral plasma membrane [GO:0016323]; cell periphery [GO:0071944]; cell surface [GO:0009986]; excitatory synapse [GO:0060076]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; filopodium membrane [GO:0031527]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; growth cone filopodium [GO:1990812]; integrin alpha3-beta1 complex [GO:0034667]; integrin complex [GO:0008305]; neuromuscular junction [GO:0031594]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; presynaptic active zone membrane [GO:0048787]; receptor complex [GO:0043235]; synaptic membrane [GO:0097060] | collagen binding [GO:0005518]; fibronectin binding [GO:0001968]; integrin binding [GO:0005178]; laminin binding [GO:0043236]; metal ion binding [GO:0046872]; protease binding [GO:0002020]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982] | 24222.950818357298 | -0.089783600585709 | 0.797359295272831 | 1 |
| P23229 | P23229 | ITA6_HUMAN | Integrin alpha-6 (CD49 antigen-like family member F) (VLA-6) (CD antigen CD49f) [Cleaved into: Integrin alpha-6 heavy chain; Integrin alpha-6 light chain; Processed integrin alpha-6 (Alpha6p)] | ITGA6 | cell adhesion mediated by integrin [GO:0033627]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; cell-substrate adhesion [GO:0031589]; cell-substrate junction assembly [GO:0007044]; cellular response to organic cyclic compound [GO:0071407]; ectodermal cell differentiation [GO:0010668]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; nail development [GO:0035878]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell migration [GO:0030335]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of GTPase activity [GO:0043547]; positive regulation of neuron projection development [GO:0010976]; positive regulation of phosphorylation [GO:0042327]; positive regulation of transcription by RNA polymerase II [GO:0045944]; skin morphogenesis [GO:0043589] | adherens junction [GO:0005912]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; integrin alpha6-beta4 complex [GO:0034676]; integrin complex [GO:0008305]; plasma membrane [GO:0005886] | cadherin binding [GO:0045296]; insulin-like growth factor I binding [GO:0031994]; integrin binding [GO:0005178]; laminin binding [GO:0043236]; metal ion binding [GO:0046872]; neuregulin binding [GO:0038132] | 8085.289147811574 | 0.178911881539872 | 0.727098418023818 | 1 |
| Q14643 | Q14643 | ITPR1_HUMAN | Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1 (IP3 receptor isoform 1) (IP3R 1) (InsP3R1) (Inositol 1,4,5 trisphosphate receptor) (Inositol 1,4,5-trisphosphate receptor type 1) (Type 1 inositol 1,4,5-trisphosphate receptor) (Type 1 InsP3 receptor) | ITPR1 | calcium ion transport [GO:0006816]; cell morphogenesis [GO:0000902]; endoplasmic reticulum calcium ion homeostasis [GO:0032469]; epithelial fluid transport [GO:0042045]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; ion channel modulating, G protein-coupled receptor signaling pathway [GO:0099105]; ligand-gated ion channel signaling pathway [GO:1990806]; negative regulation of calcium-mediated signaling [GO:0050849]; phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway [GO:0007207]; positive regulation of insulin secretion [GO:0032024]; post-embryonic development [GO:0009791]; regulation of autophagy [GO:0010506]; release of sequestered calcium ion into cytosol [GO:0051209]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; voluntary musculoskeletal movement [GO:0050882] | calcineurin complex [GO:0005955]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; nuclear inner membrane [GO:0005637]; nucleolus [GO:0005730]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; platelet dense granule membrane [GO:0031088]; platelet dense tubular network [GO:0031094]; platelet dense tubular network membrane [GO:0031095]; postsynaptic density [GO:0014069]; sarcoplasmic reticulum [GO:0016529]; Schaffer collateral - CA1 synapse [GO:0098685]; secretory granule membrane [GO:0030667]; transport vesicle membrane [GO:0030658] | calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; calcium ion transmembrane transporter activity [GO:0015085]; inositol 1,4,5 trisphosphate binding [GO:0070679]; inositol 1,4,5-trisphosphate receptor activity involved in regulation of postsynaptic cytosolic calcium levels [GO:0098695]; inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [GO:0005220]; intracellularly gated calcium channel activity [GO:0015278]; phosphatidylinositol binding [GO:0035091]; protein domain specific binding [GO:0019904] | 6409.89274909041 | -0.0968701428395749 | 0.960954659772404 | 1 |
| Q14573 | Q14573 | ITPR3_HUMAN | Inositol 1,4,5-trisphosphate receptor type 3 (IP3 receptor isoform 3) (IP3R 3) (InsP3R3) (Type 3 inositol 1,4,5-trisphosphate receptor) (Type 3 InsP3 receptor) | ITPR3 | calcium ion homeostasis [GO:0055074]; G protein-coupled receptor signaling pathway [GO:0007186]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; release of sequestered calcium ion into cytosol [GO:0051209]; response to calcium ion [GO:0051592]; sensory perception of bitter taste [GO:0050913]; sensory perception of sweet taste [GO:0050916]; sensory perception of taste [GO:0050909]; sensory perception of umami taste [GO:0050917] | apical part of cell [GO:0045177]; brush border [GO:0005903]; cytoplasm [GO:0005737]; cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nuclear outer membrane [GO:0005640]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; platelet dense tubular network membrane [GO:0031095]; receptor complex [GO:0043235]; sarcoplasmic reticulum [GO:0016529]; secretory granule membrane [GO:0030667] | calcium ion binding [GO:0005509]; inositol 1,3,4,5 tetrakisphosphate binding [GO:0043533]; inositol 1,4,5 trisphosphate binding [GO:0070679]; inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [GO:0005220]; inositol hexakisphosphate binding [GO:0000822]; intracellularly gated calcium channel activity [GO:0015278]; phosphatidylinositol binding [GO:0035091] | 4893.421749337465 | -0.246984696772943 | 0.741386707942142 | 1 |
| Q8IWB1 | Q8IWB1 | IPRI_HUMAN | Inositol 1,4,5-trisphosphate receptor-interacting protein (Protein DANGER) | ITPRIP | extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042] | membrane [GO:0016020]; nuclear outer membrane [GO:0005640]; plasma membrane [GO:0005886] | protein kinase inhibitor activity [GO:0004860] | 4732.99902230107 | 0.13524099700258 | 0.896460346457633 | 1 |
| Q9NZM3 | Q9NZM3 | ITSN2_HUMAN | Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein) | ITSN2 | cell differentiation [GO:0030154]; clathrin-dependent synaptic vesicle endocytosis [GO:0150007]; endosomal transport [GO:0016197]; positive regulation of dendrite extension [GO:1903861]; positive regulation of Rho protein signal transduction [GO:0035025] | centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intracellular vesicle [GO:0097708]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734] | calcium ion binding [GO:0005509]; guanyl-nucleotide exchange factor activity [GO:0005085]; molecular adaptor activity [GO:0060090] | 4263.561562363765 | -0.0761038344582892 | 0.895860935236097 | 1 |
| Q63ZY3 | Q63ZY3 | KANK2_HUMAN | KN motif and ankyrin repeat domain-containing protein 2 (Ankyrin repeat domain-containing protein 25) (Matrix-remodeling-associated protein 3) (SRC-1-interacting protein) (SIP) (SRC-interacting protein) (SRC1-interacting protein) | KANK2 | apoptotic process [GO:0006915]; kidney epithelium development [GO:0072073]; negative regulation of actin filament polymerization [GO:0030837]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of intracellular estrogen receptor signaling pathway [GO:0033147]; negative regulation of programmed cell death [GO:0043069]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vitamin D receptor signaling pathway [GO:0070563]; podocyte cell migration [GO:0090521]; regulation of Rho protein signal transduction [GO:0035023] | cytoplasm [GO:0005737]; mitochondrion [GO:0005739] | 10643.669886596901 | -0.0625198483500188 | 0.999858735616485 | 1 | |
| Q15046 | Q15046 | SYK_HUMAN | Lysine--tRNA ligase (EC 2.7.7.-) (EC 6.1.1.6) (Lysyl-tRNA synthetase) (LysRS) | KARS1 | basophil activation involved in immune response [GO:0002276]; diadenosine tetraphosphate biosynthetic process [GO:0015966]; ERK1 and ERK2 cascade [GO:0070371]; lysyl-tRNA aminoacylation [GO:0006430]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of inflammatory response to antigenic stimulus [GO:0002863]; positive regulation of macrophage activation [GO:0043032]; response to X-ray [GO:0010165]; tRNA processing [GO:0008033] | aminoacyl-tRNA synthetase multienzyme complex [GO:0017101]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886] | amino acid binding [GO:0016597]; ATP adenylyltransferase activity [GO:0003877]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; lysine-tRNA ligase activity [GO:0004824]; protein homodimerization activity [GO:0042803]; tRNA binding [GO:0000049] | 62092.840677229906 | -1.30594817031527E-4 | 1 | 1 |
| O75449 | O75449 | KTNA1_HUMAN | Katanin p60 ATPase-containing subunit A1 (Katanin p60 subunit A1) (EC 5.6.1.1) (p60 katanin) | KATNA1 | cell cycle [GO:0007049]; cell division [GO:0051301]; cytoplasmic microtubule organization [GO:0031122]; microtubule severing [GO:0051013] | centrosome [GO:0005813]; cytoplasm [GO:0005737]; katanin complex [GO:0008352]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; midbody [GO:0030496]; mitotic spindle pole [GO:0097431]; spindle [GO:0005819]; spindle pole [GO:0000922] | ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; isomerase activity [GO:0016853]; microtubule binding [GO:0008017]; microtubule severing ATPase activity [GO:0008568]; protein heterodimerization activity [GO:0046982] | 4300.147673947466 | 0.223544452497843 | 0.988985632017132 | 1 |
| Q9H079 | Q9H079 | KTBL1_HUMAN | KATNB1-like protein 1 (Katanin p80 subunit B-like 1) | KATNBL1 | cytoplasmic microtubule organization [GO:0031122]; positive regulation of cytoskeleton organization [GO:0051495] | cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; katanin complex [GO:0008352]; microtubule cytoskeleton [GO:0015630]; midbody [GO:0030496]; mitotic spindle [GO:0072686]; mitotic spindle pole [GO:0097431]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] | microtubule binding [GO:0008017] | 4239.167138508 | -0.344266352003889 | 0.994318428760925 | 1 |
| Q68DU8 | Q68DU8 | KCD16_HUMAN | BTB/POZ domain-containing protein KCTD16 (Potassium channel tetramerization domain-containing protein 16) | KCTD16 | protein homooligomerization [GO:0051260]; regulation of G protein-coupled receptor signaling pathway [GO:0008277] | cell projection [GO:0042995]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; receptor complex [GO:0043235] | 5399.32033041756 | -0.0861842323259268 | 0.939074412354636 | 1 | |
| Q07666 | Q07666 | KHDR1_HUMAN | KH domain-containing, RNA-binding, signal transduction-associated protein 1 (GAP-associated tyrosine phosphoprotein p62) (Src-associated in mitosis 68 kDa protein) (Sam68) (p21 Ras GTPase-activating protein-associated p62) (p68) | KHDRBS1 | G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; mRNA processing [GO:0006397]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of RNA export from nucleus [GO:0046833]; positive regulation of translational initiation [GO:0045948]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of RNA export from nucleus [GO:0046831]; spermatogenesis [GO:0007283]; T cell receptor signaling pathway [GO:0050852] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; Grb2-Sos complex [GO:0070618]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991] | DNA binding [GO:0003677]; identical protein binding [GO:0042802]; mRNA binding [GO:0003729]; poly(A) binding [GO:0008143]; poly(U) RNA binding [GO:0008266]; protein domain specific binding [GO:0019904]; protein tyrosine kinase binding [GO:1990782]; protein-containing complex binding [GO:0044877]; RNA binding [GO:0003723]; SH2 domain binding [GO:0042169]; SH3 domain binding [GO:0017124]; signaling adaptor activity [GO:0035591] | 111586.84322461451 | 0.0614398840989187 | 0.895950979599522 | 1 |
| Q8IYS2 | Q8IYS2 | K2013_HUMAN | Uncharacterized protein KIAA2013 | KIAA2013 | membrane [GO:0016020] | 18576.999913416897 | -0.0565848658672542 | 0.947394231404465 | 1 | ||
| O60333 | O60333 | KIF1B_HUMAN | Kinesin-like protein KIF1B (Klp) | KIF1B | anterograde axonal transport [GO:0008089]; apoptotic process [GO:0006915]; cytoskeleton-dependent intracellular transport [GO:0030705]; microtubule-based movement [GO:0007018]; neuromuscular synaptic transmission [GO:0007274]; neuron-neuron synaptic transmission [GO:0007270]; vesicle-mediated transport [GO:0016192] | axon [GO:0030424]; axon cytoplasm [GO:1904115]; cytoplasmic vesicle [GO:0031410]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; kinesin complex [GO:0005871]; microtubule [GO:0005874]; microtubule associated complex [GO:0005875]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; synaptic vesicle [GO:0008021] | ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; kinesin binding [GO:0019894]; microtubule binding [GO:0008017]; plus-end-directed microtubule motor activity [GO:0008574] | 10732.07424440325 | 0.153495967181585 | 0.740226326378192 | 1 |
| O43896 | O43896 | KIF1C_HUMAN | Kinesin-like protein KIF1C | KIF1C | anterograde neuronal dense core vesicle transport [GO:1990048]; cytoskeleton-dependent intracellular transport [GO:0030705]; microtubule-based movement [GO:0007018]; retrograde neuronal dense core vesicle transport [GO:1990049]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; vesicle-mediated transport [GO:0016192] | axon [GO:0030424]; axon cytoplasm [GO:1904115]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; kinesin complex [GO:0005871]; microtubule [GO:0005874] | ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; cytoskeletal motor activity [GO:0003774]; microtubule binding [GO:0008017]; plus-end-directed microtubule motor activity [GO:0008574]; RNA binding [GO:0003723] | 13395.9392217628 | -0.117570633946084 | 0.876698363652413 | 1 |
| O14782 | O14782 | KIF3C_HUMAN | Kinesin-like protein KIF3C | KIF3C | microtubule-based movement [GO:0007018]; mitotic cell cycle [GO:0000278] | ciliary tip [GO:0097542]; cilium [GO:0005929]; cytosol [GO:0005829]; kinesin complex [GO:0005871]; microtubule [GO:0005874] | ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; cytoskeletal motor activity [GO:0003774]; microtubule binding [GO:0008017]; microtubule motor activity [GO:0003777] | 647.8753107923465 | 0.554700721003325 | 0.987225001984964 | 1 |
| P33176 | P33176 | KINH_HUMAN | Kinesin-1 heavy chain (Conventional kinesin heavy chain) (Ubiquitous kinesin heavy chain) (UKHC) | KIF5B | anterograde axonal protein transport [GO:0099641]; anterograde dendritic transport of neurotransmitter receptor complex [GO:0098971]; anterograde neuronal dense core vesicle transport [GO:1990048]; axon guidance [GO:0007411]; cellular response to type II interferon [GO:0071346]; centrosome localization [GO:0051642]; cytoplasm organization [GO:0007028]; lysosome localization [GO:0032418]; microtubule-based movement [GO:0007018]; mitochondrion transport along microtubule [GO:0047497]; mitocytosis [GO:0160040]; mitotic cell cycle [GO:0000278]; natural killer cell mediated cytotoxicity [GO:0042267]; plus-end-directed vesicle transport along microtubule [GO:0072383]; positive regulation of potassium ion transport [GO:0043268]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of membrane potential [GO:0042391]; retrograde neuronal dense core vesicle transport [GO:1990049]; stress granule disassembly [GO:0035617]; synaptic vesicle transport [GO:0048489]; vesicle transport along microtubule [GO:0047496] | axon cytoplasm [GO:1904115]; centriolar satellite [GO:0034451]; ciliary rootlet [GO:0035253]; cytolytic granule membrane [GO:0101004]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; kinesin complex [GO:0005871]; membrane [GO:0016020]; microtubule [GO:0005874]; mitochondrion [GO:0005739]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; vesicle [GO:0031982] | ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; microtubule motor activity [GO:0003777]; plus-end-directed microtubule motor activity [GO:0008574]; protein-containing complex binding [GO:0044877] | 71219.9911977053 | -0.0078930573152893 | 1 | 1 |
| Q92845 | Q92845 | KIFA3_HUMAN | Kinesin-associated protein 3 (KAP-3) (KAP3) (Smg GDS-associated protein) | KIFAP3 | cardiac muscle cell apoptotic process [GO:0010659]; cilium organization [GO:0044782]; microtubule-based movement [GO:0007018]; microtubule-based process [GO:0007017]; negative regulation of cardiac muscle cell apoptotic process [GO:0010667]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of thymocyte apoptotic process [GO:0070244]; neuroblast proliferation [GO:0007405]; plus-end-directed vesicle transport along microtubule [GO:0072383]; positive regulation of calcium-dependent cell-cell adhesion [GO:0046587]; protein localization [GO:0008104]; protein-containing complex assembly [GO:0065003]; signal transduction [GO:0007165]; thymocyte apoptotic process [GO:0070242] | axoneme [GO:0005930]; centrosome [GO:0005813]; ciliary basal body [GO:0036064]; ciliary tip [GO:0097542]; ciliary transition zone [GO:0035869]; cilium [GO:0005929]; condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; kinesin II complex [GO:0016939]; microtubule cytoskeleton [GO:0015630]; periciliary membrane compartment [GO:1990075]; photoreceptor connecting cilium [GO:0032391]; photoreceptor inner segment [GO:0001917]; photoreceptor outer segment [GO:0001750] | intraciliary transport particle B binding [GO:0120170]; kinesin binding [GO:0019894]; protein phosphatase binding [GO:0019903] | 8024.090244393596 | 0.0205691069314462 | 0.985841873153667 | 1 |
| Q96EK5 | Q96EK5 | KBP_HUMAN | KIF-binding protein (KIF1-binding protein) (Kinesin family binding protein) | KIFBP | central nervous system projection neuron axonogenesis [GO:0021952]; in utero embryonic development [GO:0001701]; microtubule cytoskeleton organization [GO:0000226]; mitochondrial transport [GO:0006839]; neuron projection maintenance [GO:1990535] | cytoskeleton [GO:0005856]; mitochondrion [GO:0005739] | kinesin binding [GO:0019894] | 12511.17639430965 | 0.063094517671241 | 0.977014034995991 | 1 |
| Q07866 | Q07866 | KLC1_HUMAN | Kinesin light chain 1 (KLC 1) | KLC1 | cell adhesion [GO:0007155]; microtubule-based movement [GO:0007018]; stress granule disassembly [GO:0035617] | cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; growth cone [GO:0030426]; kinesin complex [GO:0005871]; membrane [GO:0016020]; microtubule [GO:0005874] | cytoskeletal motor activity [GO:0003774]; kinesin binding [GO:0019894] | 76017.9095235247 | 0.0418791015494858 | 0.991627297465795 | 1 |
| Q9NSK0 | Q9NSK0 | KLC4_HUMAN | Kinesin light chain 4 (KLC 4) (Kinesin-like protein 8) | KLC4 | microtubule-based movement [GO:0007018] | cytoplasm [GO:0005737]; kinesin complex [GO:0005871]; microtubule [GO:0005874] | kinesin binding [GO:0019894] | 16320.79449416695 | -0.237251575833916 | 0.889085267100183 | 1 |
| Q53GT1 | Q53GT1 | KLH22_HUMAN | Kelch-like protein 22 | KLHL22 | cell division [GO:0051301]; cellular response to amino acid stimulus [GO:0071230]; cellular response to leucine [GO:0071233]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle assembly checkpoint signaling [GO:0007094]; negative regulation of autophagy [GO:0010507]; negative regulation of type I interferon production [GO:0032480]; positive regulation of cell growth [GO:0030307]; positive regulation of TORC1 signaling [GO:1904263]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein monoubiquitination [GO:0006513]; ubiquitin-dependent protein catabolic process [GO:0006511] | centrosome [GO:0005813]; Cul3-RING ubiquitin ligase complex [GO:0031463]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; intracellular membrane-bounded organelle [GO:0043231]; lysosome [GO:0005764]; microtubule cytoskeleton [GO:0015630]; mitotic spindle [GO:0072686]; nucleus [GO:0005634]; polar microtubule [GO:0005827] | 14-3-3 protein binding [GO:0071889]; ubiquitin ligase-substrate adaptor activity [GO:1990756] | 7519.32222732672 | -0.0618951455512813 | 0.753299335571355 | 1 |
| O00505 | O00505 | IMA4_HUMAN | Importin subunit alpha-4 (Importin alpha Q2) (Qip2) (Karyopherin subunit alpha-3) (SRP1-gamma) | KPNA3 | NLS-bearing protein import into nucleus [GO:0006607]; protein import into nucleus [GO:0006606]; protein-containing complex assembly [GO:0065003]; symbiont entry into host cell [GO:0046718]; viral penetration into host nucleus [GO:0075732] | cytosol [GO:0005829]; host cell [GO:0043657]; NLS-dependent protein nuclear import complex [GO:0042564]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] | nuclear import signal receptor activity [GO:0061608]; nuclear localization sequence binding [GO:0008139] | 17906.9550916037 | 0.00161600707188861 | 0.999999999954194 | 1 |
| O60684 | O60684 | IMA7_HUMAN | Importin subunit alpha-7 (Karyopherin subunit alpha-6) | KPNA6 | entry of viral genome into host nucleus through nuclear pore complex via importin [GO:0075506]; maternal process involved in female pregnancy [GO:0060135]; NLS-bearing protein import into nucleus [GO:0006607]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of viral life cycle [GO:1903902]; protein import into nucleus [GO:0006606]; transcription by RNA polymerase II [GO:0006366]; viral genome replication [GO:0019079] | cytosol [GO:0005829]; host cell [GO:0043657]; membrane [GO:0016020]; NLS-dependent protein nuclear import complex [GO:0042564]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] | nuclear import signal receptor activity [GO:0061608]; nuclear localization sequence binding [GO:0008139] | 27776.18907966085 | -0.0122173654966545 | 0.999958195224747 | 1 |
| Q13601 | Q13601 | KRR1_HUMAN | KRR1 small subunit processome component homolog (HIV-1 Rev-binding protein 2) (KRR-R motif-containing protein 1) (Rev-interacting protein 1) (Rip-1) | KRR1 | ribosomal small subunit biogenesis [GO:0042274]; rRNA processing [GO:0006364] | chromosome [GO:0005694]; cytoplasm [GO:0005737]; intercellular bridge [GO:0045171]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; small-subunit processome [GO:0032040] | RNA binding [GO:0003723] | 10643.37853935765 | 0.105674135286908 | 0.976527841609317 | 1 |
| P02533 | P02533 | K1C14_HUMAN | Keratin, type I cytoskeletal 14 (Cytokeratin-14) (CK-14) (Keratin-14) (K14) | KRT14 | epidermis development [GO:0008544]; epithelial cell differentiation [GO:0030855]; hair cycle [GO:0042633]; intermediate filament bundle assembly [GO:0045110]; intermediate filament organization [GO:0045109]; keratinocyte differentiation [GO:0030216]; stem cell differentiation [GO:0048863] | basal part of cell [GO:0045178]; cornified envelope [GO:0001533]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intermediate filament [GO:0005882]; keratin filament [GO:0045095]; nucleus [GO:0005634] | keratin filament binding [GO:1990254]; structural constituent of cytoskeleton [GO:0005200] | 11461.97080925211 | 0.803245693383892 | 0.941582407520943 | 1 |
| P08779 | P08779 | K1C16_HUMAN | Keratin, type I cytoskeletal 16 (Cytokeratin-16) (CK-16) (Keratin-16) (K16) | KRT16 | cytoskeleton organization [GO:0007010]; epithelial cell differentiation [GO:0030855]; establishment of skin barrier [GO:0061436]; hair cycle [GO:0042633]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; intermediate filament organization [GO:0045109]; keratinization [GO:0031424]; keratinocyte differentiation [GO:0030216]; keratinocyte migration [GO:0051546]; morphogenesis of an epithelium [GO:0002009]; negative regulation of cell migration [GO:0030336] | cornified envelope [GO:0001533]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intermediate filament [GO:0005882]; keratin filament [GO:0045095]; nucleus [GO:0005634] | structural constituent of cytoskeleton [GO:0005200] | 5009.32590062077 | 0.838098939996263 | 0.919069649956595 | 1 |
| Q04695 | Q04695 | K1C17_HUMAN | Keratin, type I cytoskeletal 17 (39.1) (Cytokeratin-17) (CK-17) (Keratin-17) (K17) | KRT17 | epithelial cell differentiation [GO:0030855]; hair follicle morphogenesis [GO:0031069]; intermediate filament organization [GO:0045109]; keratinization [GO:0031424]; positive regulation of cell growth [GO:0030307]; positive regulation of hair follicle development [GO:0051798]; positive regulation of translation [GO:0045727] | cornified envelope [GO:0001533]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; intermediate filament cytoskeleton [GO:0045111]; keratin filament [GO:0045095] | structural molecule activity [GO:0005198] | 13475.7579841981 | 0.0179496455663675 | 0.999988619676363 | 1 |
| P13647 | P13647 | K2C5_HUMAN | Keratin, type II cytoskeletal 5 (58 kDa cytokeratin) (Cytokeratin-5) (CK-5) (Keratin-5) (K5) (Type-II keratin Kb5) | KRT5 | epidermis development [GO:0008544]; intermediate filament organization [GO:0045109]; intermediate filament polymerization [GO:0045107]; keratinization [GO:0031424]; regulation of cell migration [GO:0030334]; regulation of protein localization [GO:0032880]; response to mechanical stimulus [GO:0009612] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intermediate filament [GO:0005882]; keratin filament [GO:0045095]; membrane [GO:0016020]; nucleus [GO:0005634] | scaffold protein binding [GO:0097110]; structural constituent of cytoskeleton [GO:0005200]; structural constituent of skin epidermis [GO:0030280] | 19495.98927247035 | -0.216439956981208 | 0.998315286066269 | 1 |
| P02538 | P02538 | K2C6A_HUMAN | Keratin, type II cytoskeletal 6A (Cytokeratin-6A) (CK-6A) (Cytokeratin-6D) (CK-6D) (Keratin-6A) (K6A) (Type-II keratin Kb6) (allergen Hom s 5) | KRT6A | antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cell differentiation [GO:0030154]; defense response to Gram-positive bacterium [GO:0050830]; intermediate filament organization [GO:0045109]; keratinization [GO:0031424]; killing of cells of another organism [GO:0031640]; morphogenesis of an epithelium [GO:0002009]; negative regulation of entry of bacterium into host cell [GO:2000536]; positive regulation of cell population proliferation [GO:0008284]; wound healing [GO:0042060] | cytosol [GO:0005829]; extracellular exosome [GO:0070062]; keratin filament [GO:0045095]; membrane [GO:0016020]; nucleus [GO:0005634] | structural constituent of cytoskeleton [GO:0005200]; structural constituent of skin epidermis [GO:0030280] | 20657.721686292898 | -0.124087091364185 | 0.99999999997558 | 1 |
| Q14CN4 | Q14CN4 | K2C72_HUMAN | Keratin, type II cytoskeletal 72 (Cytokeratin-72) (CK-72) (Keratin-72) (K72) (Type II inner root sheath-specific keratin-K6irs2) (Type-II keratin Kb35) | KRT72 | intermediate filament organization [GO:0045109]; keratinization [GO:0031424] | cytosol [GO:0005829]; extracellular exosome [GO:0070062]; keratin filament [GO:0045095] | structural constituent of skin epidermis [GO:0030280] | 102317.68031373774 | -1.74689470436651 | 0.994199520239603 | 1 |
| P05787 | P05787 | K2C8_HUMAN | Keratin, type II cytoskeletal 8 (Cytokeratin-8) (CK-8) (Keratin-8) (K8) (Type-II keratin Kb8) | KRT8 | cell differentiation involved in embryonic placenta development [GO:0060706]; extrinsic apoptotic signaling pathway [GO:0097191]; hepatocyte apoptotic process [GO:0097284]; intermediate filament organization [GO:0045109]; keratinization [GO:0031424]; response to hydrostatic pressure [GO:0051599]; response to other organism [GO:0051707]; sarcomere organization [GO:0045214]; tumor necrosis factor-mediated signaling pathway [GO:0033209] | apicolateral plasma membrane [GO:0016327]; cell-cell junction [GO:0005911]; costamere [GO:0043034]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dystrophin-associated glycoprotein complex [GO:0016010]; extracellular exosome [GO:0070062]; intermediate filament [GO:0005882]; intermediate filament cytoskeleton [GO:0045111]; keratin filament [GO:0045095]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; sarcolemma [GO:0042383]; Z disc [GO:0030018] | protein-containing complex binding [GO:0044877]; scaffold protein binding [GO:0097110]; structural constituent of skin epidermis [GO:0030280] | 9553.27515917607 | 0.0873127442007983 | 0.98635111474109 | 1 |
| Q86UP2 | Q86UP2 | KTN1_HUMAN | Kinectin (CG-1 antigen) (Kinesin receptor) | KTN1 | microtubule-based movement [GO:0007018]; protein transport [GO:0015031] | endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; plasma membrane [GO:0005886] | cadherin binding [GO:0045296]; kinesin binding [GO:0019894]; RNA binding [GO:0003723] | 53520.085780718844 | -0.0617381224929906 | 0.999785971731791 | 1 |
| Q53H82 | Q53H82 | LACB2_HUMAN | Endoribonuclease LACTB2 (EC 3.1.27.-) (Beta-lactamase-like protein 2) | LACTB2 | secondary metabolite biosynthetic process [GO:0044550] | mitochondrial matrix [GO:0005759] | RNA endonuclease activity [GO:0004521]; single-stranded RNA binding [GO:0003727]; zinc ion binding [GO:0008270] | 9832.777759829 | 0.0477053454501025 | 0.956402716899432 | 1 |
| P24043 | P24043 | LAMA2_HUMAN | Laminin subunit alpha-2 (Laminin M chain) (Laminin-12 subunit alpha) (Laminin-2 subunit alpha) (Laminin-4 subunit alpha) (Merosin heavy chain) | LAMA2 | animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; maintenance of blood-brain barrier [GO:0035633]; muscle organ development [GO:0007517]; positive regulation of cell adhesion [GO:0045785]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of synaptic transmission, cholinergic [GO:0032224]; regulation of basement membrane organization [GO:0110011]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995]; Schwann cell differentiation [GO:0014037]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888] | basement membrane [GO:0005604]; collagen-containing extracellular matrix [GO:0062023]; dendritic spine [GO:0043197]; extracellular region [GO:0005576]; neuromuscular junction [GO:0031594]; protein complex involved in cell-matrix adhesion [GO:0098637]; sarcolemma [GO:0042383]; synaptic cleft [GO:0043083] | signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198] | 4193.398648970569 | 0.174000413456525 | 0.934209442392307 | 1 |
| O15230 | O15230 | LAMA5_HUMAN | Laminin subunit alpha-5 (Laminin-10 subunit alpha) (Laminin-11 subunit alpha) (Laminin-15 subunit alpha) | LAMA5 | branching involved in salivary gland morphogenesis [GO:0060445]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell migration [GO:0016477]; cilium assembly [GO:0060271]; hair follicle development [GO:0001942]; integrin-mediated signaling pathway [GO:0007229]; lung development [GO:0030324]; morphogenesis of a polarized epithelium [GO:0001738]; morphogenesis of embryonic epithelium [GO:0016331]; muscle organ development [GO:0007517]; odontogenesis of dentin-containing tooth [GO:0042475]; postsynapse organization [GO:0099173]; protein localization to plasma membrane [GO:0072659]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995]; regulation of epithelial cell proliferation [GO:0050678]; skeletal system morphogenesis [GO:0048705]; substrate adhesion-dependent cell spreading [GO:0034446]; trunk neural crest cell migration [GO:0036484] | basement membrane [GO:0005604]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular matrix of synaptic cleft [GO:0098965]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; glutamatergic synapse [GO:0098978]; laminin-10 complex [GO:0043259]; laminin-11 complex [GO:0043260]; laminin-5 complex [GO:0005610]; neuromuscular junction [GO:0031594]; nucleus [GO:0005634]; synaptic cleft [GO:0043083] | integrin binding [GO:0005178] | 2918.900610527245 | -0.025710061850764 | 0.880367565193191 | 1 |
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| Q15149 | |||||||||
| Q99715 | |||||||||
| P02452 | |||||||||
| P02751 | |||||||||
| P98160 | |||||||||
| P08123 | |||||||||
| P02461 | |||||||||
| P07996 | |||||||||
| Q8WWI1 | |||||||||
| P05997 | |||||||||
| P20908 | |||||||||
| Q8WUJ3 | |||||||||
| P21333 | |||||||||
| O75369 | |||||||||
| Q15063 | |||||||||
| P02786 | |||||||||
| Q12884 | |||||||||
| P12814 | |||||||||
| Q9UDY2 | |||||||||
| Q14195 | |||||||||
| Q02952 | |||||||||
| Q9NZM1 | |||||||||
| P35579 | |||||||||
| P35354 | |||||||||
| P47895 | |||||||||
| Q09666 | |||||||||
| P11717 | |||||||||
| Q14112 | |||||||||
| Q13620 | |||||||||
| P43490 | |||||||||
| Q3SY69 | |||||||||
| P17812 | |||||||||
| P21980 | |||||||||
| Q16647 | |||||||||
| P01024 | |||||||||
| Q5SW79 | |||||||||
| P06396 | |||||||||
| P12111 | |||||||||
| P35221 | |||||||||
| P12429 | |||||||||
| P78559 | |||||||||
| Q76M96 | |||||||||
| Q16881 | |||||||||
| P07093 | |||||||||
| P27487 | |||||||||
| P15144 | |||||||||
| Q9H5V8 | |||||||||
| P08729 | |||||||||
| Q04828 | |||||||||
| O94925 | |||||||||
| P08473 | |||||||||
| Q8IVL5 | |||||||||
| P35442 | |||||||||
| O60716 | |||||||||
| P08253 | |||||||||
| Q16822 | |||||||||
| Q9UJ72 | |||||||||
| Q9Y617 | |||||||||
| Q8WX93 | |||||||||
| Q32MZ4 | |||||||||
| Q6P179 | |||||||||
| P48681 | |||||||||
| O95340 | |||||||||
| P21580 | |||||||||
| Q00341 | |||||||||
| P49748 | |||||||||
| O43854 | |||||||||
| P07942 | |||||||||
| Q96KC8 | |||||||||
| Q96PD2 | |||||||||
| Q13418 | |||||||||
| Q7Z7G0 | |||||||||
| Q04446 | |||||||||
| P19022 | |||||||||
| O00469 | |||||||||
| Q8WUF5 | |||||||||
| Q14767 | |||||||||
| Q13308 | |||||||||
| P46940 | |||||||||
| Q9NZ08 | |||||||||
| O60488 | |||||||||
| P35222 | |||||||||
| Q9H4M9 | |||||||||
| Q9NZU5 | |||||||||
| Q15113 | |||||||||
| O94808 | |||||||||
| Q9UI42 | |||||||||
| Q15417 | |||||||||
| Q15582 | |||||||||
| P35908 | |||||||||
| P00750 | |||||||||
| Q9UHD8 | |||||||||
| P11047 | |||||||||
| Q8N6G6 | |||||||||
| Q05682 | |||||||||
| P17342 | |||||||||
| Q16363 | |||||||||
| Q9NR12 | |||||||||
| P05362 | |||||||||
| P00966 | |||||||||
| P05120 | |||||||||
| P15121 | |||||||||
| P04179 | |||||||||
| Q15785 | |||||||||
| O60271 | |||||||||
| Q9Y6N5 | |||||||||
| Q9P0V9 | |||||||||
| Q8IVF2 | |||||||||
| P01584 | |||||||||
| Q96AQ6 | |||||||||
| P54289 | |||||||||
| P13667 | |||||||||
| Q96HE7 | |||||||||
| P21810 | |||||||||
| Q16790 | |||||||||
| P23396 | |||||||||
| P01130 | |||||||||
| P51812 | |||||||||
| O95490 | |||||||||
| Q16222 | |||||||||
| Q7Z4N8 | |||||||||
| P08133 | |||||||||
| Q08431 | |||||||||
| P23142 | |||||||||
| Q01581 | |||||||||
| P10915 | |||||||||
| O75976 | |||||||||
| P23219 | |||||||||
| Q8IXK2 | |||||||||
| Q07954 | |||||||||
| P50225 | |||||||||
| P11413 | |||||||||
| Q5SSJ5 | |||||||||
| Q6PCE3 | |||||||||
| P05091 | |||||||||
| P49419 | |||||||||
| P41252 | |||||||||
| P50281 | |||||||||
| Q13618 | |||||||||
| Q00653 | |||||||||
| Q9BZG1 | |||||||||
| P11142 | |||||||||
| P63010 | |||||||||
| Q9UBG0 | |||||||||
| Q5GLZ8 | |||||||||
| P21266 | |||||||||
| Q9BS40 | |||||||||
| P35232 | |||||||||
| Q86VP6 | |||||||||
| P09601 | |||||||||
| Q8N8S7 | |||||||||
| Q16851 | |||||||||
| P28845 | |||||||||
| P26640 | |||||||||
| Q92626 | |||||||||
| P07686 | |||||||||
| P01583 | |||||||||
| Q96HH9 | |||||||||
| P48506 | |||||||||
| P47712 | |||||||||
| Q14314 | |||||||||
| Q53FA7 | |||||||||
| Q9H425 | |||||||||
| Q14204 | |||||||||
| P01033 | |||||||||
| Q92616 | |||||||||
| Q16666 | |||||||||
| Q99623 | |||||||||
| P23381 | |||||||||
| Q8N6Y2 | |||||||||
| P98155 | |||||||||
| P46977 | |||||||||
| Q86SQ0 | |||||||||
| Q70E73 | |||||||||
| Q6VY07 | |||||||||
| P41250 | |||||||||
| P56945 | |||||||||
| P29279 | |||||||||
| Q96C19 | |||||||||
| Q9UPN3 | |||||||||
| P26022 | |||||||||
| P00492 | |||||||||
| Q9BXS4 | |||||||||
| P50452 | |||||||||
| P05783 | |||||||||
| Q14980 | |||||||||
| Q9UBX5 | |||||||||
| O75094 | |||||||||
| Q06323 | |||||||||
| O14672 | |||||||||
| O00339 | |||||||||
| P52209 | |||||||||
| Q00325 | |||||||||
| P30044 | |||||||||
| P30740 | |||||||||
| P46734 | |||||||||
| P48307 | |||||||||
| P08648 | |||||||||
| O43175 | |||||||||
| O00116 |
