Selected Cell
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stat_data__min_2_Peptides
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| Q8TDH9 | Q8TDH9 | BL1S5_HUMAN | Biogenesis of lysosome-related organelles complex 1 subunit 5 (BLOC-1 subunit 5) (Protein Muted homolog) | BLOC1S5 | anterograde axonal transport [GO:0008089]; anterograde synaptic vesicle transport [GO:0048490]; endosome to melanosome transport [GO:0035646]; melanosome organization [GO:0032438]; melanosome transport [GO:0032402]; neuron projection development [GO:0031175]; otolith morphogenesis [GO:0032474]; positive regulation of pigment cell differentiation [GO:0050942]; vesicle-mediated transport [GO:0016192] | axon cytoplasm [GO:1904115]; BLOC-1 complex [GO:0031083]; microvesicle [GO:1990742]; transport vesicle [GO:0030133] | 5335.74846859032 | -0.197409120236831 | 0.992575898567085 | 1 | |
| A0JNW5 | A0JNW5 | BLT3B_HUMAN | Bridge-like lipid transfer protein family member 3B (Syntaxin-6 Habc-interacting protein of 164 kDa) (UHRF1-binding protein 1-like) | BLTP3B | early endosome to Golgi transport [GO:0034498]; intermembrane lipid transfer [GO:0120009] | cytosol [GO:0005829]; early endosome [GO:0005769] | GARP complex binding [GO:0062069]; lipid transfer activity [GO:0120013]; protein homodimerization activity [GO:0042803] | 3601.87484627611 | -0.0565760585142721 | 0.99639542386384 | 1 |
| P53004 | P53004 | BIEA_HUMAN | Biliverdin reductase A (BVR A) (EC 1.3.1.24) (Biliverdin-IX alpha-reductase) | BLVRA | heme catabolic process [GO:0042167] | cytosol [GO:0005829]; extracellular exosome [GO:0070062] | biliberdin reductase NAD+ activity [GO:0106276]; biliverdin reductase (NAD(P)+) activity [GO:0004074]; biliverdin reductase (NADP+) activity [GO:0106277]; nucleotide binding [GO:0000166]; zinc ion binding [GO:0008270] | 85981.75866521164 | 0.0623518295591422 | 0.932490819710027 | 1 |
| Q12982 | Q12982 | BNIP2_HUMAN | BCL2/adenovirus E1B 19 kDa protein-interacting protein 2 | BNIP2 | apoptotic process [GO:0006915]; negative regulation of apoptotic process [GO:0043066]; response to oxygen-glucose deprivation [GO:0090649] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nuclear envelope [GO:0005635]; nucleolus [GO:0005730]; perinuclear region of cytoplasm [GO:0048471] | calcium ion binding [GO:0005509]; GTPase activator activity [GO:0005096] | 15491.558392532152 | 0.0975304807947461 | 0.992748527532932 | 1 |
| Q8NFC6 | Q8NFC6 | BD1L1_HUMAN | Biorientation of chromosomes in cell division protein 1-like 1 | BOD1L1 | DNA damage response [GO:0006974]; DNA repair [GO:0006281]; replication fork processing [GO:0031297] | chromosome [GO:0005694]; nucleoplasm [GO:0005654]; Set1C/COMPASS complex [GO:0048188] | 1933.6594574317 | 0.0611340657090363 | 0.916776786962806 | 1 | |
| Q14137 | Q14137 | BOP1_HUMAN | Ribosome biogenesis protein BOP1 (Block of proliferation 1 protein) | BOP1 | cell population proliferation [GO:0008283]; cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000448]; maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000463]; regulation of cell cycle [GO:0051726]; regulation of signal transduction by p53 class mediator [GO:1901796]; ribosomal large subunit assembly [GO:0000027]; ribosome biogenesis [GO:0042254] | chromosome [GO:0005694]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; PeBoW complex [GO:0070545]; preribosome, large subunit precursor [GO:0030687]; ribonucleoprotein complex [GO:1990904] | ribonucleoprotein complex binding [GO:0043021]; RNA binding [GO:0003723] | 5740.737595511095 | -0.0549053007229803 | 0.73576125475686 | 1 |
| O60885 | O60885 | BRD4_HUMAN | Bromodomain-containing protein 4 (Protein HUNK1) | BRD4 | chromatin remodeling [GO:0006338]; DNA damage response [GO:0006974]; negative regulation by host of viral transcription [GO:0043922]; negative regulation of DNA damage checkpoint [GO:2000002]; positive regulation of canonical NF-kappaB signal transduction [GO:0043123]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of T-helper 17 cell lineage commitment [GO:2000330]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation by RNA polymerase II [GO:0032968]; regulation of inflammatory response [GO:0050727]; regulation of transcription by RNA polymerase II [GO:0006357] | chromatin [GO:0000785]; chromosome [GO:0005694]; condensed nuclear chromosome [GO:0000794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] | chromatin binding [GO:0003682]; enzyme binding [GO:0019899]; histone reader activity [GO:0140566]; lysine-acetylated histone binding [GO:0070577]; P-TEFb complex binding [GO:0106140]; p53 binding [GO:0002039]; RNA polymerase II C-terminal domain binding [GO:0099122]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; transcription cis-regulatory region binding [GO:0000976]; transcription coactivator activity [GO:0003713]; transcription coregulator activity [GO:0003712] | 2247.69062227722 | 0.154388812447282 | 0.758992835315579 | 1 |
| Q8WY22 | Q8WY22 | BRI3B_HUMAN | BRI3-binding protein (I3-binding protein) (Cervical cancer 1 proto-oncogene-binding protein KG19) (HCCRBP-1) | BRI3BP | mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739] | 19364.298209098 | 0.115362677521345 | 0.656593111141598 | 1 | ||
| Q8TDN6 | Q8TDN6 | BRX1_HUMAN | Ribosome biogenesis protein BRX1 homolog (Brix domain-containing protein 2) | BRIX1 | rRNA processing [GO:0006364] | chromosome [GO:0005694]; nucleolus [GO:0005730] | RNA binding [GO:0003723]; rRNA binding [GO:0019843] | 13753.1290256385 | 0.0334905952189597 | 0.999992396784316 | 1 |
| Q5VW32 | Q5VW32 | BROX_HUMAN | BRO1 domain-containing protein BROX (BRO1 domain- and CAAX motif-containing protein) | BROX | mitotic nuclear membrane reassembly [GO:0007084] | extracellular exosome [GO:0070062]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965] | 20678.516265087448 | -0.126252235299673 | 0.820188172681265 | 1 | |
| Q96K17 | Q96K17 | BT3L4_HUMAN | Transcription factor BTF3 homolog 4 (Basic transcription factor 3-like 4) | BTF3L4 | 85584.11345560869 | 0.193496823532303 | 0.70804143496451 | 1 | |||
| Q7KYR7 | Q7KYR7 | BT2A1_HUMAN | Butyrophilin subfamily 2 member A1 | BTN2A1 | lipid metabolic process [GO:0006629]; regulation of cytokine production [GO:0001817]; T cell receptor signaling pathway [GO:0050852] | external side of plasma membrane [GO:0009897]; plasma membrane [GO:0005886] | signaling receptor binding [GO:0005102] | 7331.837492022865 | 0.238658489311053 | 0.79017317103966 | 1 |
| O43684 | O43684 | BUB3_HUMAN | Mitotic checkpoint protein BUB3 | BUB3 | attachment of spindle microtubules to kinetochore [GO:0008608]; cell division [GO:0051301]; meiotic cell cycle [GO:0051321]; mitotic spindle assembly checkpoint signaling [GO:0007094]; protein localization to kinetochore [GO:0034501] | bub1-bub3 complex [GO:1990298]; cytosol [GO:0005829]; kinetochore [GO:0000776]; mitotic checkpoint complex [GO:0033597]; nucleoplasm [GO:0005654] | ubiquitin binding [GO:0043130] | 39820.75074229225 | -0.0107479910869806 | 0.999928264461886 | 1 |
| P41223 | P41223 | BUD31_HUMAN | Protein BUD31 homolog (Protein EDG-2) (Protein G10 homolog) | BUD31 | mRNA splicing, via spliceosome [GO:0000398]; positive regulation of androgen receptor activity [GO:2000825] | chromatin [GO:0000785]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spliceosomal complex [GO:0005681]; U2-type catalytic step 2 spliceosome [GO:0071007] | nuclear receptor binding [GO:0016922]; nuclear receptor coactivator activity [GO:0030374] | 9663.430998234166 | 0.0151717836874569 | 0.989697861555997 | 1 |
| Q13895 | Q13895 | BYST_HUMAN | Bystin | BYSL | maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; regulation of protein localization to nucleolus [GO:1904749]; ribosome biogenesis [GO:0042254]; rRNA processing [GO:0006364]; stem cell proliferation [GO:0072089]; trophectodermal cell differentiation [GO:0001829] | apical part of cell [GO:0045177]; chromosome [GO:0005694]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; preribosome, small subunit precursor [GO:0030688] | RNA binding [GO:0003723]; snoRNA binding [GO:0030515] | 5984.807856076365 | 0.081835795892429 | 0.741710807354971 | 1 |
| Q9Y6E2 | Q9Y6E2 | 5MP1_HUMAN | eIF5-mimic protein 1 (Basic leucine zipper and W2 domain-containing protein 2) | BZW2 | regulation of translational initiation [GO:0006446] | cytoplasm [GO:0005737]; membrane [GO:0016020] | cadherin binding [GO:0045296] | 14598.667351337499 | -0.0126226399223674 | 0.999993013894061 | 1 |
| Q8WUR7 | Q8WUR7 | CO040_HUMAN | UPF0235 protein C15orf40 | C15orf40 | cytoplasm [GO:0005737] | 15842.58670849585 | 0.310088364707423 | 0.963169863005492 | 1 | ||
| Q9HAS0 | Q9HAS0 | NJMU_HUMAN | Protein Njmu-R1 | C17orf75 | intracellular protein transport [GO:0006886]; vesicle tethering to Golgi [GO:0099041] | cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; trans-Golgi network [GO:0005802] | 7487.76065510614 | -0.0135308811711572 | 0.99999982311194 | 1 | |
| Q6ZSJ8 | Q6ZSJ8 | CA122_HUMAN | Uncharacterized protein C1orf122 (Protein ALAESM) | C1orf122 | 22566.2124440731 | 0.196334535650301 | 0.858316148624855 | 1 | |||
| Q9BV19 | Q9BV19 | CA050_HUMAN | Uncharacterized protein C1orf50 | C1orf50 | identical protein binding [GO:0042802] | 7994.5293505370555 | -0.0399892960999045 | 0.900446228093697 | 1 | ||
| P09871 | P09871 | C1S_HUMAN | Complement C1s subcomponent (EC 3.4.21.42) (C1 esterase) (Complement component 1 subcomponent s) [Cleaved into: Complement C1s subcomponent heavy chain; Complement C1s subcomponent light chain] | C1S | complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; proteolysis [GO:0006508] | blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615] | calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252] | 12472.30960471465 | -0.154003778169812 | 0.879405439428084 | 1 |
| P0C0L4;P0C0L5 | P0C0L4 | CO4A_HUMAN | Complement C4-A (Acidic complement C4) (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2) [Cleaved into: Complement C4 beta chain; Complement C4-A alpha chain; C4a anaphylatoxin; C4b-A; C4d-A; Complement C4 gamma chain] | C4A | complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; positive regulation of apoptotic cell clearance [GO:2000427] | axon [GO:0030424]; blood microparticle [GO:0072562]; dendrite [GO:0030425]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; synapse [GO:0045202] | complement component C1q complex binding [GO:0001849]; endopeptidase inhibitor activity [GO:0004866] | 10352.06872382825 | -0.0402915942575068 | 0.965584656212242 | 1 |
| Q9P1Z2 | Q9P1Z2 | CACO1_HUMAN | Calcium-binding and coiled-coil domain-containing protein 1 (Calphoglin) (Coiled-coil coactivator protein) (Sarcoma antigen NY-SAR-3) | CALCOCO1 | intracellular steroid hormone receptor signaling pathway [GO:0030518]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription by RNA polymerase II [GO:0045944]; signal transduction [GO:0007165]; Wnt signaling pathway [GO:0016055] | chromatin [GO:0000785]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleus [GO:0005634] | beta-catenin binding [GO:0008013]; chromatin binding [GO:0003682]; metal ion binding [GO:0046872]; nuclear receptor coactivator activity [GO:0030374]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; transcription cis-regulatory region binding [GO:0000976]; transcription coactivator activity [GO:0003713]; transcription coregulator activity [GO:0003712] | 5562.530213980084 | 0.0968141027258808 | 0.689839180421034 | 1 |
| Q13137 | Q13137 | CACO2_HUMAN | Calcium-binding and coiled-coil domain-containing protein 2 (Antigen nuclear dot 52 kDa protein) (Nuclear domain 10 protein NDP52) (Nuclear domain 10 protein 52) (Nuclear dot protein 52) | CALCOCO2 | positive regulation of autophagosome maturation [GO:1901098]; response to type II interferon [GO:0034341]; viral process [GO:0016032]; xenophagy [GO:0098792] | autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; PML body [GO:0016605] | metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803] | 8365.805249713136 | 0.00517023761922387 | 0.988406641562608 | 1 |
| Q13554 | Q13554 | KCC2B_HUMAN | Calcium/calmodulin-dependent protein kinase type II subunit beta (CaM kinase II subunit beta) (CaMK-II subunit beta) (EC 2.7.11.17) | CAMK2B | cell differentiation [GO:0030154]; nervous system development [GO:0007399]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of dendritic spine morphogenesis [GO:0061003]; positive regulation of neuron projection development [GO:0010976]; positive regulation of synapse maturation [GO:0090129]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of calcium ion transport [GO:0051924]; regulation of dendritic spine development [GO:0060998]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neuron migration [GO:2001222]; regulation of skeletal muscle adaptation [GO:0014733]; regulation of synapse structural plasticity [GO:0051823]; signal transduction [GO:0007165] | calcium- and calmodulin-dependent protein kinase complex [GO:0005954]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; sarcoplasmic reticulum membrane [GO:0033017]; synapse [GO:0045202] | actin binding [GO:0003779]; ATP binding [GO:0005524]; calcium-dependent protein serine/threonine kinase activity [GO:0009931]; calmodulin binding [GO:0005516]; calmodulin-dependent protein kinase activity [GO:0004683]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein serine kinase activity [GO:0106310] | 48921.1863645935 | 0.13511355920607 | 0.989416327135992 | 1 |
| P49069 | P49069 | CAMLG_HUMAN | Guided entry of tail-anchored proteins factor CAMLG (Calcium signal-modulating cyclophilin ligand) | CAMLG | B cell homeostasis [GO:0001782]; defense response [GO:0006952]; epidermal growth factor receptor signaling pathway [GO:0007173]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of protein ubiquitination [GO:0031397]; protein insertion into ER membrane [GO:0045048]; protein stabilization [GO:0050821]; receptor recycling [GO:0001881]; signal transduction [GO:0007165]; tail-anchored membrane protein insertion into ER membrane [GO:0071816]; vesicle-mediated transport [GO:0016192] | cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; GET complex [GO:0043529]; membrane [GO:0016020] | ubiquitin protein ligase binding [GO:0031625] | 10017.923279950455 | -0.0872204622888603 | 0.770115344190874 | 1 |
| Q5T5Y3 | Q5T5Y3 | CAMP1_HUMAN | Calmodulin-regulated spectrin-associated protein 1 | CAMSAP1 | cytoplasmic microtubule organization [GO:0031122]; cytoskeleton organization [GO:0007010]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of microtubule depolymerization [GO:0007026]; neuron projection development [GO:0031175]; regulation of cell morphogenesis [GO:0022604]; regulation of microtubule polymerization [GO:0031113] | cytoplasm [GO:0005737]; microtubule [GO:0005874]; microtubule minus-end [GO:0036449]; microtubule organizing center [GO:0005815] | calmodulin binding [GO:0005516]; microtubule binding [GO:0008017]; microtubule minus-end binding [GO:0051011]; spectrin binding [GO:0030507] | 4514.03073597415 | -0.00388002192628313 | 0.99999088016484 | 1 |
| Q08AD1 | Q08AD1 | CAMP2_HUMAN | Calmodulin-regulated spectrin-associated protein 2 (Calmodulin-regulated spectrin-associated protein 1-like protein 1) | CAMSAP2 | axon development [GO:0061564]; cytoplasmic microtubule organization [GO:0031122]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of microtubule depolymerization [GO:0007026]; regulation of dendrite development [GO:0050773]; regulation of Golgi organization [GO:1903358]; regulation of microtubule polymerization [GO:0031113]; regulation of organelle organization [GO:0033043] | ciliary basal body [GO:0036064]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; microtubule end [GO:1990752]; microtubule minus-end [GO:0036449] | calmodulin binding [GO:0005516]; microtubule minus-end binding [GO:0051011]; spectrin binding [GO:0030507] | 6828.6067899697755 | 0.0426700577955494 | 0.99970766251798 | 1 |
| Q01518 | Q01518 | CAP1_HUMAN | Adenylyl cyclase-associated protein 1 (CAP 1) | CAP1 | actin filament organization [GO:0007015]; activation of adenylate cyclase activity [GO:0007190]; ameboidal-type cell migration [GO:0001667]; cAMP-mediated signaling [GO:0019933]; cell morphogenesis [GO:0000902]; establishment or maintenance of cell polarity [GO:0007163]; receptor-mediated endocytosis [GO:0006898]; signal transduction [GO:0007165] | azurophil granule lumen [GO:0035578]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886] | actin binding [GO:0003779]; adenylate cyclase binding [GO:0008179] | 217749.1640924345 | -0.0578677695794981 | 0.999988433132467 | 1 |
| P40123 | P40123 | CAP2_HUMAN | Adenylyl cyclase-associated protein 2 (CAP 2) | CAP2 | actin filament organization [GO:0007015]; activation of adenylate cyclase activity [GO:0007190]; cAMP-mediated signaling [GO:0019933]; cell morphogenesis [GO:0000902]; establishment or maintenance of cell polarity [GO:0007163]; presynaptic actin cytoskeleton organization [GO:0099140]; signal transduction [GO:0007165] | cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069] | actin binding [GO:0003779]; adenylate cyclase binding [GO:0008179]; identical protein binding [GO:0042802] | 39870.58079071095 | -0.0378003318383621 | 0.976275042694871 | 1 |
| P07384 | P07384 | CAN1_HUMAN | Calpain-1 catalytic subunit (EC 3.4.22.52) (Calcium-activated neutral proteinase 1) (CANP 1) (Calpain mu-type) (Calpain-1 large subunit) (Cell proliferation-inducing gene 30 protein) (Micromolar-calpain) (muCANP) | CAPN1 | mammary gland involution [GO:0060056]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; receptor catabolic process [GO:0032801]; regulation of catalytic activity [GO:0050790]; regulation of macroautophagy [GO:0016241]; regulation of NMDA receptor activity [GO:2000310]; self proteolysis [GO:0097264] | calpain complex [GO:0110158]; cornified envelope [GO:0001533]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lysosome [GO:0005764]; membrane [GO:0016020]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886] | calcium ion binding [GO:0005509]; calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; peptidase activity [GO:0008233] | 54491.149733635204 | 0.0364978349005349 | 0.999654110924776 | 1 |
| Q96LW7 | Q96LW7 | CAR19_HUMAN | Caspase recruitment domain-containing protein 19 (Bcl10-interacting CARD protein) (BinCARD) | CARD19 | negative regulation of canonical NF-kappaB signal transduction [GO:0043124] | cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739]; nucleus [GO:0005634] | CARD domain binding [GO:0050700] | 7507.225841415515 | 0.113683157993927 | 0.724453706047596 | 1 |
| Q86X55 | Q86X55 | CARM1_HUMAN | Histone-arginine methyltransferase CARM1 (EC 2.1.1.319) (Coactivator-associated arginine methyltransferase 1) (Protein arginine N-methyltransferase 4) | CARM1 | methylation [GO:0032259]; negative regulation of dendrite development [GO:2000171]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell apoptotic process [GO:1904037]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of transcription by RNA polymerase I [GO:0045943]; regulation of DNA-templated transcription [GO:0006355]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; replication fork reversal [GO:0071932]; response to cAMP [GO:0051591] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear replication fork [GO:0043596]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] | beta-catenin binding [GO:0008013]; DNA-binding transcription factor binding [GO:0140297]; histone arginine N-methyltransferase activity [GO:0008469]; histone H3R17 methyltransferase activity [GO:0035642]; histone H3R2 methyltransferase activity [GO:0070611]; histone methyltransferase activity [GO:0042054]; lysine-acetylated histone binding [GO:0070577]; nuclear receptor coactivator activity [GO:0030374]; protein methyltransferase activity [GO:0008276]; protein-arginine N-methyltransferase activity [GO:0016274]; protein-arginine omega-N asymmetric methyltransferase activity [GO:0035242]; transcription cis-regulatory region binding [GO:0000976]; transcription coactivator activity [GO:0003713] | 17758.33118040555 | 0.0349813638519894 | 0.998623802294851 | 1 |
| Q5VZK9 | Q5VZK9 | CARL1_HUMAN | F-actin-uncapping protein LRRC16A (CARMIL homolog) (Capping protein regulator and myosin 1 linker protein 1) (Capping protein, Arp2/3 and myosin-I linker homolog 1) (Capping protein, Arp2/3 and myosin-I linker protein 1) (Leucine-rich repeat-containing protein 16A) | CARMIL1 | actin filament network formation [GO:0051639]; actin filament organization [GO:0007015]; barbed-end actin filament uncapping [GO:0051638]; cell migration [GO:0016477]; lamellipodium assembly [GO:0030032]; macropinocytosis [GO:0044351]; negative regulation of barbed-end actin filament capping [GO:2000813]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell migration [GO:0030335]; positive regulation of lamellipodium organization [GO:1902745]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; regulation of Arp2/3 complex-mediated actin nucleation [GO:0034315]; ruffle organization [GO:0031529]; urate metabolic process [GO:0046415] | cell leading edge [GO:0031252]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; filamentous actin [GO:0031941]; lamellipodium [GO:0030027]; macropinosome [GO:0044354]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] | protein-containing complex binding [GO:0044877] | 5759.8052358748755 | -0.158324208720416 | 0.960541742874349 | 1 |
| P55212 | P55212 | CASP6_HUMAN | Caspase-6 (CASP-6) (CSP-6) (EC 3.4.22.59) (Apoptotic protease Mch-2) [Cleaved into: Caspase-6 subunit p18 (Caspase-6 subunit p20); Caspase-6 subunit p11 (Caspase-6 subunit p10)] | CASP6 | activation of innate immune response [GO:0002218]; apoptotic process [GO:0006915]; cellular response to staurosporine [GO:0072734]; epithelial cell differentiation [GO:0030855]; hepatocyte apoptotic process [GO:0097284]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; positive regulation of apoptotic process [GO:0043065]; positive regulation of necroptotic process [GO:0060545]; positive regulation of neuron apoptotic process [GO:0043525]; protein autoprocessing [GO:0016540]; proteolysis [GO:0006508]; pyroptosis [GO:0070269]; regulation of programmed cell death [GO:0043067] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] | cysteine-type endopeptidase activity [GO:0004197]; cysteine-type endopeptidase activity involved in apoptotic process [GO:0097153]; cysteine-type endopeptidase activity involved in execution phase of apoptosis [GO:0097200]; cysteine-type peptidase activity [GO:0008234]; identical protein binding [GO:0042802] | 4533.870121449319 | -0.136794974969845 | 0.77194161025109 | 1 |
| P55210 | P55210 | CASP7_HUMAN | Caspase-7 (CASP-7) (EC 3.4.22.60) (Apoptotic protease Mch-3) (CMH-1) (ICE-like apoptotic protease 3) (ICE-LAP3) [Cleaved into: Caspase-7 subunit p20; Caspase-7 subunit p11] | CASP7 | apoptotic process [GO:0006915]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to staurosporine [GO:0072734]; defense response to bacterium [GO:0042742]; execution phase of apoptosis [GO:0097194]; fibroblast apoptotic process [GO:0044346]; heart development [GO:0007507]; lymphocyte apoptotic process [GO:0070227]; neuron apoptotic process [GO:0051402]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of plasma membrane repair [GO:1905686]; protein catabolic process [GO:0030163]; protein maturation [GO:0051604]; protein processing [GO:0016485]; proteolysis [GO:0006508]; response to UV [GO:0009411]; striated muscle cell differentiation [GO:0051146] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] | aspartic-type endopeptidase activity [GO:0004190]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type endopeptidase activity involved in apoptotic process [GO:0097153]; cysteine-type endopeptidase activity involved in execution phase of apoptosis [GO:0097200]; cysteine-type peptidase activity [GO:0008234]; peptidase activity [GO:0008233]; RNA binding [GO:0003723] | 4825.2626685438445 | 0.0307079219969348 | 0.998177054628701 | 1 |
| P04040 | P04040 | CATA_HUMAN | Catalase (EC 1.11.1.6) | CAT | aerobic respiration [GO:0009060]; cellular detoxification of hydrogen peroxide [GO:0061692]; cellular response to growth factor stimulus [GO:0071363]; cholesterol metabolic process [GO:0008203]; hemoglobin metabolic process [GO:0020027]; hydrogen peroxide catabolic process [GO:0042744]; negative regulation of apoptotic process [GO:0043066]; osteoblast differentiation [GO:0001649]; positive regulation of cell division [GO:0051781]; positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction [GO:0051897]; response to activity [GO:0014823]; response to cadmium ion [GO:0046686]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to fatty acid [GO:0070542]; response to hydrogen peroxide [GO:0042542]; response to hyperoxia [GO:0055093]; response to hypoxia [GO:0001666]; response to inactivity [GO:0014854]; response to insulin [GO:0032868]; response to L-ascorbic acid [GO:0033591]; response to lead ion [GO:0010288]; response to light intensity [GO:0009642]; response to ozone [GO:0010193]; response to phenylpropanoid [GO:0080184]; response to reactive oxygen species [GO:0000302]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to xenobiotic stimulus [GO:0009410]; triglyceride metabolic process [GO:0006641]; ureteric bud development [GO:0001657]; UV protection [GO:0009650] | catalase complex [GO:0062151]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]; peroxisomal matrix [GO:0005782]; peroxisomal membrane [GO:0005778]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774] | aminoacylase activity [GO:0004046]; antioxidant activity [GO:0016209]; catalase activity [GO:0004096]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; oxidoreductase activity, acting on peroxide as acceptor [GO:0016684]; protein homodimerization activity [GO:0042803] | 34773.26289005475 | -0.017375635945742 | 0.999973694061343 | 1 |
| P22681 | P22681 | CBL_HUMAN | E3 ubiquitin-protein ligase CBL (EC 2.3.2.27) (Casitas B-lineage lymphoma proto-oncogene) (Proto-oncogene c-Cbl) (RING finger protein 55) (RING-type E3 ubiquitin transferase CBL) (Signal transduction protein CBL) | CBL | cellular response to hypoxia [GO:0071456]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response [GO:0006974]; entry of bacterium into host cell [GO:0035635]; male gonad development [GO:0008584]; mast cell degranulation [GO:0043303]; negative regulation of apoptotic process [GO:0043066]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction [GO:0051897]; positive regulation of receptor-mediated endocytosis [GO:0048260]; protein autoubiquitination [GO:0051865]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of platelet-derived growth factor receptor-alpha signaling pathway [GO:2000583]; regulation of Rap protein signal transduction [GO:0032487]; response to activity [GO:0014823]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to starvation [GO:0042594]; response to testosterone [GO:0033574]; signal transduction [GO:0007165]; ubiquitin-dependent endocytosis [GO:0070086]; ubiquitin-dependent protein catabolic process [GO:0006511] | cilium [GO:0005929]; cytosol [GO:0005829]; flotillin complex [GO:0016600]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; growth cone [GO:0030426]; membrane raft [GO:0045121]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886] | cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; ephrin receptor binding [GO:0046875]; phosphatidylinositol 3-kinase regulatory subunit binding [GO:0036312]; phosphotyrosine residue binding [GO:0001784]; receptor tyrosine kinase binding [GO:0030971]; SH3 domain binding [GO:0017124]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842] | 7240.676754318335 | 0.0820190573380893 | 0.724003896158409 | 1 |
| Q13191 | Q13191 | CBLB_HUMAN | E3 ubiquitin-protein ligase CBL-B (EC 2.3.2.27) (Casitas B-lineage lymphoma proto-oncogene b) (RING finger protein 56) (RING-type E3 ubiquitin transferase CBL-B) (SH3-binding protein CBL-B) (Signal transduction protein CBL-B) | CBLB | CD4-positive, alpha-beta T cell proliferation [GO:0035739]; immune response [GO:0006955]; intracellular signal transduction [GO:0035556]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of T cell receptor signaling pathway [GO:0050860]; NLS-bearing protein import into nucleus [GO:0006607]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of T cell anergy [GO:0002669]; protein catabolic process [GO:0030163]; protein ubiquitination [GO:0016567]; regulation of platelet-derived growth factor receptor-alpha signaling pathway [GO:2000583]; signal transduction [GO:0007165]; T cell anergy [GO:0002870]; T cell receptor signaling pathway [GO:0050852] | cytosol [GO:0005829]; membrane raft [GO:0045121]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] | calcium ion binding [GO:0005509]; phosphotyrosine residue binding [GO:0001784]; receptor tyrosine kinase binding [GO:0030971]; SH3 domain binding [GO:0017124]; ubiquitin protein ligase activity [GO:0061630]; zinc ion binding [GO:0008270] | 4649.351712744305 | -0.451716708117659 | 0.714378984472506 | 1 |
| Q5T0F9 | Q5T0F9 | C2D1B_HUMAN | Coiled-coil and C2 domain-containing protein 1B (Five prime repressor element under dual repression-binding protein 2) (FRE under dual repression-binding protein 2) (Freud-2) | CC2D1B | regulation of transcription by RNA polymerase II [GO:0006357] | cytosol [GO:0005829]; endosome membrane [GO:0010008]; intracellular membrane-bounded organelle [GO:0043231]; nuclear envelope [GO:0005635]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] | DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] | 8985.252494881335 | -0.150069359893736 | 0.695328325950807 | 1 |
| Q9H6E4 | Q9H6E4 | CC134_HUMAN | Coiled-coil domain-containing protein 134 | CCDC134 | angiogenesis [GO:0001525]; embryonic hemopoiesis [GO:0035162]; embryonic liver development [GO:1990402]; placenta development [GO:0001890]; regulation of ossification [GO:0030278]; ventricular system development [GO:0021591] | cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleus [GO:0005634] | 5033.0079526524405 | 0.0294779266961907 | 0.968069826639987 | 1 | |
| Q96MW1 | Q96MW1 | CCD43_HUMAN | Coiled-coil domain-containing protein 43 | CCDC43 | cytosol [GO:0005829] | 16108.15754908535 | 0.121675844876416 | 0.799223595923973 | 1 | ||
| Q9P031 | Q9P031 | TAP26_HUMAN | Thyroid transcription factor 1-associated protein 26 (TTF-1-associated protein 26) (Coiled-coil domain-containing protein 59) (TTF-1-associated protein BR2) | CCDC59 | nucleoplasm [GO:0005654] | RNA binding [GO:0003723] | 12615.962129225849 | 0.0830053220929608 | 0.830129926485382 | 1 | |
| Q16204 | Q16204 | CCDC6_HUMAN | Coiled-coil domain-containing protein 6 (Papillary thyroid carcinoma-encoded protein) (Protein H4) | CCDC6 | cytoskeleton [GO:0005856]; cytosol [GO:0005829] | identical protein binding [GO:0042802]; SH3 domain binding [GO:0017124]; structural constituent of cytoskeleton [GO:0005200] | 29854.96976677295 | -0.0198031036988819 | 0.999846941691514 | 1 | |
| Q9Y3X0 | Q9Y3X0 | CCDC9_HUMAN | Coiled-coil domain-containing protein 9 | CCDC9 | exon-exon junction complex [GO:0035145] | RNA binding [GO:0003723] | 27945.91045339195 | 0.0513007873043853 | 0.94727781186124 | 1 | |
| Q9GZT6 | Q9GZT6 | CC90B_HUMAN | Coiled-coil domain-containing protein 90B, mitochondrial | CCDC90B | mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739] | 3632.9214765582847 | 0.0575342598745367 | 0.923879117571572 | 1 | ||
| Q7Z6B0 | Q7Z6B0 | CCD91_HUMAN | Coiled-coil domain-containing protein 91 (GGA-binding partner) (p56 accessory protein) | CCDC91 | Golgi to lysosome transport [GO:0090160]; protein transport [GO:0015031] | cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; trans-Golgi network [GO:0005802] | 18415.6750056499 | 0.115943348299371 | 0.81119198133508 | 1 | |
| Q567U6 | Q567U6 | CCD93_HUMAN | Coiled-coil domain-containing protein 93 | CCDC93 | endocytic recycling [GO:0032456]; Golgi to plasma membrane transport [GO:0006893]; protein transport [GO:0015031] | early endosome [GO:0005769]; intracellular membrane-bounded organelle [GO:0043231] | 16925.76494980685 | -0.0193640875025366 | 0.999999942105367 | 1 | |
| Q6ZUT6 | Q6ZUT6 | CCD9B_HUMAN | Coiled-coil domain-containing protein 9B | CCDC9B | RNA binding [GO:0003723] | 9280.077794704195 | -0.131220002719158 | 0.788065207426939 | 1 | ||
| P24385 | P24385 | CCND1_HUMAN | G1/S-specific cyclin-D1 (B-cell lymphoma 1 protein) (BCL-1) (BCL-1 oncogene) (PRAD1 oncogene) | CCND1 | cell division [GO:0051301]; DNA damage response [GO:0006974]; endoplasmic reticulum unfolded protein response [GO:0030968]; fat cell differentiation [GO:0045444]; G1/S transition of mitotic cell cycle [GO:0000082]; lactation [GO:0007595]; liver regeneration [GO:0097421]; mammary gland alveolus development [GO:0060749]; mammary gland epithelial cell proliferation [GO:0033598]; mitotic G1 DNA damage checkpoint signaling [GO:0031571]; negative regulation of epithelial cell differentiation [GO:0030857]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron differentiation [GO:0030182]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of mammary gland epithelial cell proliferation [GO:0033601]; positive regulation of protein phosphorylation [GO:0001934]; re-entry into mitotic cell cycle [GO:0000320]; response to leptin [GO:0044321]; response to UV-A [GO:0070141]; response to xenobiotic stimulus [GO:0009410]; Wnt signaling pathway [GO:0016055] | bicellular tight junction [GO:0005923]; centrosome [GO:0005813]; cyclin D1-CDK4 complex [GO:0097128]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription repressor complex [GO:0017053] | cyclin-dependent protein serine/threonine kinase activator activity [GO:0061575]; cyclin-dependent protein serine/threonine kinase regulator activity [GO:0016538]; enzyme binding [GO:0019899]; histone deacetylase binding [GO:0042826]; proline-rich region binding [GO:0070064]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; transcription corepressor activity [GO:0003714] | 7097.76803387775 | -0.0519473215589282 | 0.908013052762763 | 1 |
| O75909 | O75909 | CCNK_HUMAN | Cyclin-K | CCNK | cell cycle [GO:0007049]; cell division [GO:0051301]; DNA damage response [GO:0006974]; negative regulation by host of viral genome replication [GO:0044828]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; positive regulation of transcription elongation by RNA polymerase II [GO:0032968]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of signal transduction [GO:0009966]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription by RNA polymerase II [GO:0006366] | cyclin K-CDK12 complex [GO:0002944]; cyclin K-CDK13 complex [GO:0002945]; cyclin/CDK positive transcription elongation factor complex [GO:0008024]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] | cyclin-dependent protein serine/threonine kinase activator activity [GO:0061575]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; protein kinase binding [GO:0019901]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353] | 3183.71258935487 | -0.0619343314335675 | 0.809182563283914 | 1 |
| Q8ND76 | Q8ND76 | CCNY_HUMAN | Cyclin-Y (Cyc-Y) (Cyclin box protein 1) (Cyclin fold protein 1) (cyclin-X) | CCNY | cell division [GO:0051301]; G2/M transition of mitotic cell cycle [GO:0000086]; positive regulation of autophagy [GO:0010508]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; regulation of canonical Wnt signaling pathway [GO:0060828]; spermatogenesis [GO:0007283]; Wnt signaling pathway [GO:0016055] | cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasmic cyclin-dependent protein kinase holoenzyme complex [GO:0000308]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886] | cyclin-dependent protein serine/threonine kinase activator activity [GO:0061575]; cyclin-dependent protein serine/threonine kinase regulator activity [GO:0016538]; protein kinase binding [GO:0019901] | 11733.8649776287 | -0.107621995858729 | 0.841467624348158 | 1 |
| P78371 | P78371 | TCPB_HUMAN | T-complex protein 1 subunit beta (TCP-1-beta) (CCT-beta) (Chaperonin containing T-complex polypeptide 1 subunit 2) | CCT2 | binding of sperm to zona pellucida [GO:0007339]; chaperone mediated protein folding independent of cofactor [GO:0051086]; chaperone-mediated protein complex assembly [GO:0051131]; chaperone-mediated protein folding [GO:0061077]; positive regulation of establishment of protein localization to telomere [GO:1904851]; positive regulation of protein localization to Cajal body [GO:1904871]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomerase RNA localization to Cajal body [GO:1904874]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein folding [GO:0006457]; protein stabilization [GO:0050821]; scaRNA localization to Cajal body [GO:0090666] | azurophil granule lumen [GO:0035578]; cell body [GO:0044297]; chaperonin-containing T-complex [GO:0005832]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; microtubule [GO:0005874]; zona pellucida receptor complex [GO:0002199] | ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-dependent protein folding chaperone [GO:0140662]; protein folding chaperone [GO:0044183]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082] | 120699.5395898865 | -0.0373497650400483 | 0.999841258306421 | 1 |
| P49368 | P49368 | TCPG_HUMAN | T-complex protein 1 subunit gamma (TCP-1-gamma) (CCT-gamma) (Chaperonin containing T-complex polypeptide 1 subunit 3) (hTRiC5) | CCT3 | binding of sperm to zona pellucida [GO:0007339]; chaperone-mediated protein folding [GO:0061077]; positive regulation of establishment of protein localization to telomere [GO:1904851]; positive regulation of protein localization to Cajal body [GO:1904871]; positive regulation of telomerase RNA localization to Cajal body [GO:1904874]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein folding [GO:0006457]; protein stabilization [GO:0050821] | cell body [GO:0044297]; chaperonin-containing T-complex [GO:0005832]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microtubule [GO:0005874]; zona pellucida receptor complex [GO:0002199] | ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-dependent protein folding chaperone [GO:0140662]; protein folding chaperone [GO:0044183]; RNA binding [GO:0003723]; unfolded protein binding [GO:0051082] | 91310.07054478335 | -0.0038091693545048 | 0.999999999999923 | 1 |
| P50991 | P50991 | TCPD_HUMAN | T-complex protein 1 subunit delta (TCP-1-delta) (CCT-delta) (Chaperonin containing T-complex polypeptide 1 subunit 4) (Stimulator of TAR RNA-binding) | CCT4 | binding of sperm to zona pellucida [GO:0007339]; chaperone-mediated protein folding [GO:0061077]; positive regulation of establishment of protein localization to telomere [GO:1904851]; positive regulation of protein localization to Cajal body [GO:1904871]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomerase RNA localization to Cajal body [GO:1904874]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein folding [GO:0006457]; protein stabilization [GO:0050821]; scaRNA localization to Cajal body [GO:0090666] | cell body [GO:0044297]; cell projection [GO:0042995]; centrosome [GO:0005813]; chaperonin-containing T-complex [GO:0005832]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; melanosome [GO:0042470]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; zona pellucida receptor complex [GO:0002199] | ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-dependent protein folding chaperone [GO:0140662]; protein folding chaperone [GO:0044183]; RNA binding [GO:0003723]; unfolded protein binding [GO:0051082] | 96729.42739468065 | 0.00728821166523962 | 0.999999969665568 | 1 |
| P48643 | P48643 | TCPE_HUMAN | T-complex protein 1 subunit epsilon (TCP-1-epsilon) (CCT-epsilon) (Chaperonin containing T-complex polypeptide 1 subunit 5) | CCT5 | binding of sperm to zona pellucida [GO:0007339]; chaperone-mediated protein folding [GO:0061077]; positive regulation of establishment of protein localization to telomere [GO:1904851]; positive regulation of protein localization to Cajal body [GO:1904871]; positive regulation of telomerase RNA localization to Cajal body [GO:1904874]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein folding [GO:0006457]; protein stabilization [GO:0050821]; response to virus [GO:0009615] | cell body [GO:0044297]; centrosome [GO:0005813]; chaperonin-containing T-complex [GO:0005832]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microtubule [GO:0005874] | ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-dependent protein folding chaperone [GO:0140662]; beta-tubulin binding [GO:0048487]; G-protein beta-subunit binding [GO:0031681]; mRNA 3'-UTR binding [GO:0003730]; mRNA 5'-UTR binding [GO:0048027]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082] | 76989.6070563996 | 0.00128376702671271 | 1 | 1 |
| P40227 | P40227 | TCPZ_HUMAN | T-complex protein 1 subunit zeta (TCP-1-zeta) (Acute morphine dependence-related protein 2) (CCT-zeta-1) (Chaperonin containing T-complex polypeptide 1 subunit 6A) (HTR3) (Tcp20) | CCT6A | chaperone-mediated protein folding [GO:0061077]; positive regulation of establishment of protein localization to telomere [GO:1904851]; positive regulation of protein localization to Cajal body [GO:1904871]; positive regulation of telomerase RNA localization to Cajal body [GO:1904874]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein folding [GO:0006457]; protein stabilization [GO:0050821] | chaperonin-containing T-complex [GO:0005832]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microtubule [GO:0005874] | ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-dependent protein folding chaperone [GO:0140662]; protein folding chaperone [GO:0044183]; RNA binding [GO:0003723]; unfolded protein binding [GO:0051082]; WD40-repeat domain binding [GO:0071987] | 67677.7492335944 | 0.0433014545553114 | 0.932025996669293 | 1 |
| Q99832 | Q99832 | TCPH_HUMAN | T-complex protein 1 subunit eta (TCP-1-eta) (CCT-eta) (Chaperonin containing T-complex polypeptide 1 subunit 7) (HIV-1 Nef-interacting protein) [Cleaved into: T-complex protein 1 subunit eta, N-terminally processed] | CCT7 | binding of sperm to zona pellucida [GO:0007339]; chaperone-mediated protein folding [GO:0061077]; positive regulation of establishment of protein localization to telomere [GO:1904851]; positive regulation of protein localization to Cajal body [GO:1904871]; positive regulation of telomerase RNA localization to Cajal body [GO:1904874]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein folding [GO:0006457]; protein stabilization [GO:0050821] | cell body [GO:0044297]; chaperonin-containing T-complex [GO:0005832]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microtubule [GO:0005874] | ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-dependent protein folding chaperone [GO:0140662]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082] | 68363.48437495345 | -0.0154568523130054 | 0.999999998300982 | 1 |
| P50990 | P50990 | TCPQ_HUMAN | T-complex protein 1 subunit theta (TCP-1-theta) (CCT-theta) (Chaperonin containing T-complex polypeptide 1 subunit 8) (Renal carcinoma antigen NY-REN-15) | CCT8 | binding of sperm to zona pellucida [GO:0007339]; chaperone-mediated protein folding [GO:0061077]; positive regulation of establishment of protein localization to telomere [GO:1904851]; positive regulation of protein localization to Cajal body [GO:1904871]; positive regulation of telomerase RNA localization to Cajal body [GO:1904874]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein folding [GO:0006457]; protein stabilization [GO:0050821] | azurophil granule lumen [GO:0035578]; cell body [GO:0044297]; centrosome [GO:0005813]; chaperonin-containing T-complex [GO:0005832]; cilium [GO:0005929]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intermediate filament cytoskeleton [GO:0045111]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; secretory granule lumen [GO:0034774]; zona pellucida receptor complex [GO:0002199] | ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-dependent protein folding chaperone [GO:0140662]; cadherin binding [GO:0045296]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082] | 159094.675864822 | -0.0166401025052511 | 0.999999997738227 | 1 |
| P86790;P86791 | P86790 | CCZ1B_HUMAN | Vacuolar fusion protein CCZ1 homolog B (Vacuolar fusion protein CCZ1 homolog-like) | CCZ1B | vesicle-mediated transport [GO:0016192] | intracellular membrane-bounded organelle [GO:0043231]; lysosomal membrane [GO:0005765]; Mon1-Ccz1 complex [GO:0035658] | 7725.27632543873 | -0.0757531007209018 | 0.87069522716831 | 1 | |
| Q6YHK3 | Q6YHK3 | CD109_HUMAN | CD109 antigen (150 kDa TGF-beta-1-binding protein) (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7) (Platelet-specific Gov antigen) (p180) (r150) (CD antigen CD109) | CD109 | hair follicle development [GO:0001942]; keratinocyte proliferation [GO:0043616]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of stem cell proliferation [GO:2000647]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of wound healing [GO:0061045]; osteoclast fusion [GO:0072675]; regulation of keratinocyte differentiation [GO:0045616]; stem cell proliferation [GO:0072089] | cell surface [GO:0009986]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; side of membrane [GO:0098552] | serine-type endopeptidase inhibitor activity [GO:0004867]; transforming growth factor beta binding [GO:0050431] | 14947.45062686305 | -0.0582504196321271 | 0.941686339559004 | 1 |
| P14209 | P14209 | CD99_HUMAN | CD99 antigen (12E7) (E2 antigen) (Protein MIC2) (T-cell surface glycoprotein E2) (CD antigen CD99) | CD99 | homotypic cell-cell adhesion [GO:0034109]; positive regulation of neutrophil extravasation [GO:2000391]; T cell extravasation [GO:0072683] | cytoplasm [GO:0005737]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886] | 361709.93173747195 | 0.132970415301186 | 0.766373076944783 | 1 | |
| Q8TCZ2 | Q8TCZ2 | C99L2_HUMAN | CD99 antigen-like protein 2 (MIC2-like protein 1) (CD antigen CD99) | CD99L2 | diapedesis [GO:0050904]; homotypic cell-cell adhesion [GO:0034109]; positive regulation of neutrophil extravasation [GO:2000391]; positive regulation of T cell extravasation [GO:2000409]; T cell extravasation [GO:0072683] | adherens junction [GO:0005912]; cell surface [GO:0009986]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886] | 47893.960262707944 | -0.0327475984218587 | 0.94753271208514 | 1 | |
| O75794 | O75794 | CD123_HUMAN | Translation initiation factor eIF2 assembly protein (Cell division cycle protein 123 homolog) (Protein D123) (HT-1080) (PZ32) | CDC123 | eukaryotic translation initiation factor 2 complex assembly [GO:1905143] | cytoplasm [GO:0005737] | ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; protein folding chaperone [GO:0044183] | 7499.760982975566 | 0.40524529332006 | 0.836482440697541 | 1 |
| P49427 | P49427 | UB2R1_HUMAN | Ubiquitin-conjugating enzyme E2 R1 (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme R1) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme R1) (Ubiquitin-conjugating enzyme E2-32 kDa complementing) (Ubiquitin-conjugating enzyme E2-CDC34) (Ubiquitin-protein ligase R1) | CDC34 | cellular response to interferon-beta [GO:0035458]; DNA replication initiation [GO:0006270]; G1/S transition of mitotic cell cycle [GO:0000082]; negative regulation of cAMP-mediated signaling [GO:0043951]; positive regulation of inclusion body assembly [GO:0090261]; positive regulation of neuron apoptotic process [GO:0043525]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K48-linked ubiquitination [GO:0070936]; protein modification process [GO:0036211]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; response to growth factor [GO:0070848]; ubiquitin-dependent protein catabolic process [GO:0006511] | cytosol [GO:0005829]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] | ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin-protein transferase activity [GO:0004842] | 12002.27115067752 | 0.628492597285368 | 0.662982585263638 | 1 |
| O60508 | O60508 | PRP17_HUMAN | Pre-mRNA-processing factor 17 (Cell division cycle 40 homolog) (EH-binding protein 3) (Ehb3) (PRP17 homolog) (hPRP17) | CDC40 | embryonic brain development [GO:1990403]; mRNA splicing, via spliceosome [GO:0000398] | catalytic step 2 spliceosome [GO:0071013]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; U2-type catalytic step 2 spliceosome [GO:0071007] | mRNA binding [GO:0003729]; RNA binding [GO:0003723] | 3644.2485476064903 | -0.146450435989718 | 0.699594670518862 | 1 |
| P60953 | P60953 | CDC42_HUMAN | Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein) | CDC42 | actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; actin filament organization [GO:0007015]; adherens junction organization [GO:0034332]; cardiac conduction system development [GO:0003161]; cardiac neural crest cell migration involved in outflow tract morphogenesis [GO:0003253]; Cdc42 protein signal transduction [GO:0032488]; cell junction assembly [GO:0034329]; cellular response to type II interferon [GO:0071346]; dendritic cell migration [GO:0036336]; dendritic spine morphogenesis [GO:0060997]; embryonic heart tube development [GO:0035050]; endocytosis [GO:0006897]; endothelin receptor signaling pathway involved in heart process [GO:0086101]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of Golgi localization [GO:0051683]; establishment or maintenance of cell polarity [GO:0007163]; filopodium assembly [GO:0046847]; Golgi organization [GO:0007030]; heart contraction [GO:0060047]; integrin-mediated signaling pathway [GO:0007229]; macrophage differentiation [GO:0030225]; modification of synaptic structure [GO:0099563]; modulation by host of viral process [GO:0044788]; negative regulation of protein-containing complex assembly [GO:0031333]; neuron fate determination [GO:0048664]; neuropilin signaling pathway [GO:0038189]; nuclear migration [GO:0007097]; organelle transport along microtubule [GO:0072384]; phagocytosis, engulfment [GO:0006911]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cytokinesis [GO:0032467]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction [GO:0051897]; positive regulation of pinocytosis [GO:0048549]; positive regulation of pseudopodium assembly [GO:0031274]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of synapse structural plasticity [GO:0051835]; protein localization [GO:0008104]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of filopodium assembly [GO:0051489]; regulation of lamellipodium assembly [GO:0010591]; regulation of mitotic nuclear division [GO:0007088]; regulation of modification of postsynaptic structure [GO:0099159]; regulation of postsynapse organization [GO:0099175]; regulation of stress fiber assembly [GO:0051492]; sprouting angiogenesis [GO:0002040]; submandibular salivary gland formation [GO:0060661]; substantia nigra development [GO:0021762]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071] | apical part of cell [GO:0045177]; cell-cell junction [GO:0005911]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; Golgi membrane [GO:0000139]; Golgi transport complex [GO:0017119]; leading edge membrane [GO:0031256]; membrane [GO:0016020]; midbody [GO:0030496]; mitotic spindle [GO:0072686]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; secretory granule [GO:0030141]; spindle midzone [GO:0051233]; storage vacuole [GO:0000322] | apolipoprotein A-I receptor binding [GO:0034191]; G protein activity [GO:0003925]; GBD domain binding [GO:0032427]; GTP binding [GO:0005525]; GTP-dependent protein binding [GO:0030742]; GTPase activity [GO:0003924]; identical protein binding [GO:0042802]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein kinase binding [GO:0019901]; thioesterase binding [GO:0031996]; ubiquitin protein ligase activity [GO:0061630] | 182261.71721631952 | 0.00136877971072451 | 0.999999975340149 | 1 |
| Q9Y5S2 | Q9Y5S2 | MRCKB_HUMAN | Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (CDC42BP-beta) (DMPK-like beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (MRCK beta) (Myotonic dystrophy protein kinase-like beta) | CDC42BPB | actin cytoskeleton organization [GO:0030036]; actomyosin structure organization [GO:0031032]; cell migration [GO:0016477]; cytoskeleton organization [GO:0007010]; establishment or maintenance of cell polarity [GO:0007163]; protein phosphorylation [GO:0006468]; signal transduction [GO:0007165] | actomyosin [GO:0042641]; cell leading edge [GO:0031252]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; lamellipodium [GO:0030027]; plasma membrane [GO:0005886] | ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; protein-containing complex binding [GO:0044877]; small GTPase binding [GO:0031267] | 13581.15692890635 | -0.20795635264553 | 0.76515928096425 | 1 |
| Q99459 | Q99459 | CDC5L_HUMAN | Cell division cycle 5-like protein (Cdc5-like protein) (Pombe cdc5-related protein) | CDC5L | cell cycle [GO:0007049]; DNA damage checkpoint signaling [GO:0000077]; DNA repair [GO:0006281]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] | catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; Prp19 complex [GO:0000974]; spliceosomal complex [GO:0005681]; U2-type catalytic step 2 spliceosome [GO:0071007] | DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]; WD40-repeat domain binding [GO:0071987] | 8687.014878245263 | -0.0408422956180726 | 0.999999998743142 | 1 |
| Q6P1J9 | Q6P1J9 | CDC73_HUMAN | Parafibromin (Cell division cycle protein 73 homolog) (Hyperparathyroidism 2 protein) | CDC73 | cell cycle [GO:0007049]; cellular response to lipopolysaccharide [GO:0071222]; endodermal cell fate commitment [GO:0001711]; mRNA 3'-end processing [GO:0031124]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of myeloid cell differentiation [GO:0045638]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of cell cycle G1/S phase transition [GO:1902808]; positive regulation of mRNA 3'-end processing [GO:0031442]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation by RNA polymerase II [GO:0032968]; positive regulation of Wnt signaling pathway [GO:0030177]; protein destabilization [GO:0031648]; recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex [GO:0034402]; regulation of cell growth [GO:0001558]; stem cell population maintenance [GO:0019827]; transcription elongation by RNA polymerase II [GO:0006368]; Wnt signaling pathway [GO:0016055] | Cdc73/Paf1 complex [GO:0016593]; chromosome, telomeric region [GO:0000781]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] | RNA polymerase II complex binding [GO:0000993] | 6500.596851717915 | -0.0777998348334353 | 0.964407785552384 | 1 |
| O14735 | O14735 | CDIPT_HUMAN | CDP-diacylglycerol--inositol 3-phosphatidyltransferase (EC 2.7.8.11) (Phosphatidylinositol synthase) (PI synthase) (PtdIns synthase) | CDIPT | phosphatidylinositol biosynthetic process [GO:0006661] | endoplasmic reticulum membrane [GO:0005789]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; plasma membrane [GO:0005886] | CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity [GO:0003881]; metal ion binding [GO:0046872] | 10868.085099402899 | -0.531906202982654 | 0.944365184887814 | 1 |
| P21127;Q9UQ88 | P21127 | CD11B_HUMAN | Cyclin-dependent kinase 11B (EC 2.7.11.22) (Cell division cycle 2-like protein kinase 1) (CLK-1) (Cell division protein kinase 11B) (Galactosyltransferase-associated protein kinase p58/GTA) (PITSLRE serine/threonine-protein kinase CDC2L1) (p58 CLK-1) | CDK11B | apoptotic process [GO:0006915]; mitotic cell cycle [GO:0000278]; protein phosphorylation [GO:0006468]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell growth [GO:0001558]; regulation of centrosome cycle [GO:0046605]; regulation of DNA-templated transcription [GO:0006355]; regulation of mitotic cell cycle [GO:0007346]; regulation of mRNA processing [GO:0050684]; regulation of RNA splicing [GO:0043484] | cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; nucleus [GO:0005634] | ATP binding [GO:0005524]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; RNA binding [GO:0003723] | 9039.91734278629 | -0.0385859227250213 | 0.944396786997764 | 1 |
| Q00536 | Q00536 | CDK16_HUMAN | Cyclin-dependent kinase 16 (EC 2.7.11.22) (Cell division protein kinase 16) (PCTAIRE-motif protein kinase 1) (Serine/threonine-protein kinase PCTAIRE-1) | CDK16 | exocytosis [GO:0006887]; growth hormone secretion [GO:0030252]; neuron projection development [GO:0031175]; positive regulation of autophagy [GO:0010508]; protein phosphorylation [GO:0006468]; regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061178]; spermatogenesis [GO:0007283] | cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; microtubule cytoskeleton [GO:0015630]; neuron projection [GO:0043005]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; synaptic vesicle [GO:0008021] | ATP binding [GO:0005524]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] | 7852.687536780385 | -0.278593086549994 | 0.707190910702136 | 1 |
| P50613 | P50613 | CDK7_HUMAN | Cyclin-dependent kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (39 kDa protein kinase) (p39 Mo15) (CDK-activating kinase 1) (Cell division protein kinase 7) (Serine/threonine-protein kinase 1) (TFIIH basal transcription factor complex kinase subunit) | CDK7 | cell cycle [GO:0007049]; cell division [GO:0051301]; DNA repair [GO:0006281]; phosphorylation [GO:0016310]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein stabilization [GO:0050821]; regulation of cell cycle [GO:0051726]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription initiation at RNA polymerase II promoter [GO:0006367] | CAK-ERCC2 complex [GO:0070516]; cyclin-dependent protein kinase activating kinase holoenzyme complex [GO:0019907]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; fibrillar center [GO:0001650]; male germ cell nucleus [GO:0001673]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; transcription factor TFIIH core complex [GO:0000439]; transcription factor TFIIH holo complex [GO:0005675]; transcription factor TFIIK complex [GO:0070985] | ATP binding [GO:0005524]; ATP-dependent activity, acting on DNA [GO:0008094]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353] | 1346.206207629809 | 0.0784011043548314 | 0.969004623879419 | 1 |
| Q9NXV6 | Q9NXV6 | CARF_HUMAN | CDKN2A-interacting protein (Collaborator of ARF) | CDKN2AIP | DNA damage response [GO:0006974]; negative regulation of cell growth [GO:0030308]; positive regulation of cell growth [GO:0030307]; positive regulation of signal transduction [GO:0009967]; regulation of protein stability [GO:0031647] | granular component [GO:0001652]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654] | p53 binding [GO:0002039]; RNA binding [GO:0003723] | 5560.12379465826 | -0.0847575531126166 | 0.983193721411627 | 1 |
| O95674 | O95674 | CDS2_HUMAN | Phosphatidate cytidylyltransferase 2 (EC 2.7.7.41) (CDP-DAG synthase 2) (CDP-DG synthase 2) (CDP-diacylglycerol synthase 2) (CDS 2) (CDP-diglyceride pyrophosphorylase 2) (CDP-diglyceride synthase 2) (CTP:phosphatidate cytidylyltransferase 2) | CDS2 | CDP-diacylglycerol biosynthetic process [GO:0016024]; lipid droplet formation [GO:0140042]; phosphatidylglycerol biosynthetic process [GO:0006655] | endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743] | phosphatidate cytidylyltransferase activity [GO:0004605] | 18493.2102576466 | -0.0275627512032968 | 0.929090066236042 | 1 |
| P49716 | P49716 | CEBPD_HUMAN | CCAAT/enhancer-binding protein delta (C/EBP delta) (Nuclear factor NF-IL6-beta) (NF-IL6-beta) | CEBPD | fat cell differentiation [GO:0045444]; hematopoietic progenitor cell differentiation [GO:0002244]; inner ear development [GO:0048839]; integrated stress response signaling [GO:0140467]; negative regulation of DNA-templated transcription [GO:0045892]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of cell differentiation [GO:0045595]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription by RNA polymerase II [GO:0006366] | chromatin [GO:0000785]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase II transcription regulator complex [GO:0090575] | DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837] | 7528.9472920414155 | -0.129960342230485 | 0.891224998119561 | 1 |
| Q03701 | Q03701 | CEBPZ_HUMAN | CCAAT/enhancer-binding protein zeta (CCAAT-box-binding transcription factor) (CBF) (CCAAT-binding factor) | CEBPZ | positive regulation of transcription by RNA polymerase II [GO:0045944] | CCAAT-binding factor complex [GO:0016602]; nucleus [GO:0005634] | RNA binding [GO:0003723]; transcription coactivator activity [GO:0003713] | 4089.01579916242 | -0.0908302688807336 | 0.831075939085823 | 1 |
| Q92879 | Q92879 | CELF1_HUMAN | CUGBP Elav-like family member 1 (CELF-1) (50 kDa nuclear polyadenylated RNA-binding protein) (Bruno-like protein 2) (CUG triplet repeat RNA-binding protein 1) (CUG-BP1) (CUG-BP- and ETR-3-like factor 1) (Deadenylation factor CUG-BP) (Embryo deadenylation element-binding protein homolog) (EDEN-BP homolog) (RNA-binding protein BRUNOL-2) | CELF1 | embryo development ending in birth or egg hatching [GO:0009792]; germ cell development [GO:0007281]; mRNA destabilization [GO:0061157]; mRNA processing [GO:0006397]; mRNA splice site recognition [GO:0006376]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; positive regulation of gene expression [GO:0010628]; post-transcriptional gene silencing [GO:0016441]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of inflammatory response [GO:0050727]; regulation of RNA splicing [GO:0043484]; regulatory ncRNA-mediated post-transcriptional gene silencing [GO:0035194] | cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinucleolar compartment [GO:0097356]; ribonucleoprotein complex [GO:1990904] | BRE binding [GO:0042835]; mRNA 3'-UTR binding [GO:0003730]; mRNA binding [GO:0003729]; mRNA regulatory element binding translation repressor activity [GO:0000900]; pre-mRNA binding [GO:0036002]; RNA binding [GO:0003723] | 5528.737189909405 | 0.248667335222318 | 0.881195558383892 | 1 |
| O95319 | O95319 | CELF2_HUMAN | CUGBP Elav-like family member 2 (CELF-2) (Bruno-like protein 3) (CUG triplet repeat RNA-binding protein 2) (CUG-BP2) (CUG-BP- and ETR-3-like factor 2) (ELAV-type RNA-binding protein 3) (ETR-3) (Neuroblastoma apoptosis-related RNA-binding protein) (hNAPOR) (RNA-binding protein BRUNOL-3) | CELF2 | mRNA splice site recognition [GO:0006376]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of heart contraction [GO:0008016]; RNA processing [GO:0006396] | cytoplasm [GO:0005737]; Flemming body [GO:0090543]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904] | mRNA 3'-UTR binding [GO:0003730]; pre-mRNA binding [GO:0036002]; RNA binding [GO:0003723] | 10178.22006204907 | 0.172094972425224 | 0.749524437454484 | 1 |
| Q8N111 | Q8N111 | CEND_HUMAN | Cell cycle exit and neuronal differentiation protein 1 (BM88 antigen) | CEND1 | adult walking behavior [GO:0007628]; cerebellar granular layer maturation [GO:0021686]; cerebellar Purkinje cell differentiation [GO:0021702]; negative regulation of cerebellar granule cell precursor proliferation [GO:0021941]; radial glia guided migration of cerebellar granule cell [GO:0021933] | membrane [GO:0016020] | 10462.5333541299 | -0.054609843899507 | 0.906807324405569 | 1 | |
| Q9Y4F5 | Q9Y4F5 | C170B_HUMAN | Centrosomal protein of 170 kDa protein B (Centrosomal protein 170B) (Cep170B) | CEP170B | cytoplasm [GO:0005737]; microtubule [GO:0005874] | 9642.32639474394 | -0.00577246360732619 | 0.999999999178269 | 1 | ||
| Q9C0F1 | Q9C0F1 | CEP44_HUMAN | Centrosomal protein of 44 kDa (Cep44) (HBV PreS1-transactivated protein 3) (PS1TP3) | CEP44 | centriole replication [GO:0007099]; centriole-centriole cohesion [GO:0010457]; centrosome cycle [GO:0007098] | centriole [GO:0005814]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; midbody [GO:0030496]; spindle pole [GO:0000922] | microtubule binding [GO:0008017] | 1770.011641024935 | 0.310898839977342 | 0.872913117827995 | 1 |
| Q96G23 | Q96G23 | CERS2_HUMAN | Ceramide synthase 2 (CerS2) (LAG1 longevity assurance homolog 2) (SP260) (Sphingosine N-acyltransferase CERS2) (EC 2.3.1.24) (Tumor metastasis-suppressor gene 1 protein) (Very-long-chain ceramide synthase CERS2) (EC 2.3.1.297) | CERS2 | ceramide biosynthetic process [GO:0046513]; negative regulation of axon regeneration [GO:0048681]; negative regulation of Schwann cell migration [GO:1900148]; negative regulation of Schwann cell proliferation involved in axon regeneration [GO:1905045]; regulation of lipid metabolic process [GO:0019216]; response to immobilization stress [GO:0035902]; sphingolipid biosynthetic process [GO:0030148] | endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020] | DNA binding [GO:0003677]; sphingosine N-acyltransferase activity [GO:0050291] | 15063.70610028125 | 0.105189533342792 | 0.852446174427268 | 1 |
| Q9Y281 | Q9Y281 | COF2_HUMAN | Cofilin-2 (Cofilin, muscle isoform) | CFL2 | actin filament depolymerization [GO:0030042]; actin filament fragmentation [GO:0030043]; actin filament severing [GO:0051014]; muscle cell cellular homeostasis [GO:0046716]; positive regulation of actin filament depolymerization [GO:0030836]; sarcomere organization [GO:0045214]; skeletal muscle tissue development [GO:0007519] | actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; I band [GO:0031674]; nuclear matrix [GO:0016363]; Z disc [GO:0030018] | actin filament binding [GO:0051015] | 106222.634040632 | 0.076503212868337 | 0.703468777383554 | 1 |
| Q9UFW8 | Q9UFW8 | CGBP1_HUMAN | CGG triplet repeat-binding protein 1 (CGG-binding protein 1) (20 kDa CGG-binding protein) (p20-CGGBP DNA-binding protein) | CGGBP1 | epigenetic regulation of gene expression [GO:0040029]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of gene expression [GO:0010468] | nucleoplasm [GO:0005654]; nucleus [GO:0005634] | DNA-binding transcription factor binding [GO:0140297]; double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802] | 11760.40041933745 | -0.131798025126677 | 0.807337683965135 | 1 |
| Q99674 | Q99674 | CGRE1_HUMAN | Cell growth regulator with EF hand domain protein 1 (Cell growth regulatory gene 11 protein) (Hydrophobestin) | CGREF1 | cell adhesion [GO:0007155]; cell cycle [GO:0007049]; negative regulation of cell population proliferation [GO:0008285]; regulation of cell cycle [GO:0051726] | extracellular region [GO:0005576] | calcium ion binding [GO:0005509] | 30962.8450531611 | 0.0217335915721537 | 0.999540332374608 | 1 |
| Q96JM3 | Q96JM3 | CHAP1_HUMAN | Chromosome alignment-maintaining phosphoprotein 1 (Zinc finger protein 828) | CHAMP1 | attachment of mitotic spindle microtubules to kinetochore [GO:0051315]; protein localization to kinetochore [GO:0034501]; protein localization to microtubule [GO:0035372]; sister chromatid biorientation [GO:0031134] | condensed chromosome [GO:0000793]; cytoplasm [GO:0005737]; kinetochore [GO:0000776]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spindle [GO:0005819] | metal ion binding [GO:0046872] | 2231.5875873323303 | -0.0902868765509181 | 0.804978241604853 | 1 |
| O14647 | O14647 | CHD2_HUMAN | Chromodomain-helicase-DNA-binding protein 2 (CHD-2) (EC 3.6.4.12) (ATP-dependent helicase CHD2) | CHD2 | DNA damage response [GO:0006974]; gene expression [GO:0010467]; hematopoietic stem cell differentiation [GO:0060218]; muscle organ development [GO:0007517]; nucleosome organization [GO:0034728]; regulation of transcription by RNA polymerase II [GO:0006357] | chromatin [GO:0000785]; nucleus [GO:0005634] | ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-dependent chromatin remodeler activity [GO:0140658]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; helicase activity [GO:0004386]; histone binding [GO:0042393]; RNA binding [GO:0003723]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] | 32006.53608785355 | 0.150029635961288 | 0.796115506124871 | 1 |
| P24386 | P24386 | RAE1_HUMAN | Rab proteins geranylgeranyltransferase component A 1 (Choroideremia protein) (Rab escort protein 1) (REP-1) (TCD protein) | CHM | intracellular protein transport [GO:0006886]; protein geranylgeranylation [GO:0018344]; protein targeting to membrane [GO:0006612]; small GTPase-mediated signal transduction [GO:0007264]; vesicle-mediated transport [GO:0016192]; visual perception [GO:0007601] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; Rab-protein geranylgeranyltransferase complex [GO:0005968] | GDP-dissociation inhibitor activity [GO:0005092]; GTPase activator activity [GO:0005096]; Rab geranylgeranyltransferase activity [GO:0004663]; small GTPase binding [GO:0031267] | 13748.221726856049 | 0.109698607624785 | 0.670471041690599 | 1 |
| Q9P2E5 | Q9P2E5 | CHPF2_HUMAN | Chondroitin sulfate glucuronyltransferase (EC 2.4.1.226) (CSGlcA-T) (Chondroitin glucuronyltransferase) (Chondroitin polymerizing factor 2) (ChPF-2) (Chondroitin synthase 3) (ChSy-3) (N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase) | CHPF2 | chondroitin sulfate biosynthetic process [GO:0030206] | Golgi cisterna membrane [GO:0032580]; Golgi membrane [GO:0000139]; membrane [GO:0016020] | glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity [GO:0047238]; N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity [GO:0050510] | 7544.0238275657 | -0.119463687100217 | 0.999062361017102 | 1 |
| Q9NRB3 | Q9NRB3 | CHSTC_HUMAN | Carbohydrate sulfotransferase 12 (EC 2.8.2.5) (Chondroitin 4-O-sulfotransferase 2) (Chondroitin 4-sulfotransferase 2) (C4ST-2) (C4ST2) (Sulfotransferase Hlo) | CHST12 | carbohydrate biosynthetic process [GO:0016051]; chondroitin sulfate biosynthetic process [GO:0030206]; dermatan sulfate biosynthetic process [GO:0030208]; proteoglycan biosynthetic process [GO:0030166] | Golgi membrane [GO:0000139]; membrane [GO:0016020] | 3'-phosphoadenosine 5'-phosphosulfate binding [GO:0050656]; chondroitin 4-sulfotransferase activity [GO:0047756]; sulfotransferase activity [GO:0008146] | 4644.08761562519 | 0.0743728279353053 | 0.978934388115195 | 1 |
| Q86X52 | Q86X52 | CHSS1_HUMAN | Chondroitin sulfate synthase 1 (EC 2.4.1.175) (EC 2.4.1.226) (Chondroitin glucuronyltransferase 1) (Chondroitin synthase 1) (ChSy-1) (Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase 1) (N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 1) (N-acetylgalactosaminyltransferase 1) | CHSY1 | bone morphogenesis [GO:0060349]; chondrocyte development [GO:0002063]; chondroitin sulfate biosynthetic process [GO:0030206]; negative regulation of ossification [GO:0030279]; positive regulation of smoothened signaling pathway [GO:0045880]; proximal/distal pattern formation [GO:0009954]; response to nutrient levels [GO:0031667]; sulfation [GO:0051923] | extracellular region [GO:0005576]; Golgi cisterna membrane [GO:0032580]; Golgi membrane [GO:0000139]; membrane [GO:0016020] | glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity [GO:0047238]; metal ion binding [GO:0046872]; N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity [GO:0050510] | 2927.4158806233054 | 1.46523795743374 | 0.960395765068425 | 1 |
| Q8WUH1 | Q8WUH1 | CHUR_HUMAN | Protein Churchill | CHURC1 | fibroblast growth factor receptor signaling pathway [GO:0008543]; positive regulation of DNA-templated transcription [GO:0045893] | zinc ion binding [GO:0008270] | 25219.6749120639 | 0.00162786574264789 | 0.999410481416573 | 1 | |
| Q9Y3D0 | Q9Y3D0 | CIA2B_HUMAN | Cytosolic iron-sulfur assembly component 2B (MSS19-interacting protein of 18 kDa) (Mitotic spindle-associated MMXD complex subunit MIP18) (Protein FAM96B) | CIAO2B | chromosome segregation [GO:0007059]; iron-sulfur cluster assembly [GO:0016226]; protein maturation by [4Fe-4S] cluster transfer [GO:0106035]; protein maturation by iron-sulfur cluster transfer [GO:0097428] | CIA complex [GO:0097361]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; midbody [GO:0030496]; MMXD complex [GO:0071817]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spindle [GO:0005819] | 16270.176462172501 | 0.062937142650436 | 0.956333726588205 | 1 | |
| Q14011 | Q14011 | CIRBP_HUMAN | Cold-inducible RNA-binding protein (A18 hnRNP) (Glycine-rich RNA-binding protein CIRP) | CIRBP | mRNA stabilization [GO:0048255]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; positive regulation of translation [GO:0045727]; response to cold [GO:0009409]; response to UV [GO:0009411]; stress granule assembly [GO:0034063] | cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spliceosomal complex [GO:0005681] | mRNA 3'-UTR binding [GO:0003730]; RNA binding [GO:0003723]; small ribosomal subunit rRNA binding [GO:0070181]; translation repressor activity [GO:0030371] | 123909.86102972951 | 0.136483693622679 | 0.682589313316111 | 1 |
| Q9NZ45 | Q9NZ45 | CISD1_HUMAN | CDGSH iron-sulfur domain-containing protein 1 (Cysteine transaminase CISD1) (EC 2.6.1.3) (MitoNEET) | CISD1 | protein maturation by [2Fe-2S] cluster transfer [GO:0106034]; regulation of autophagy [GO:0010506]; regulation of cellular respiration [GO:0043457] | mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739] | 2 iron, 2 sulfur cluster binding [GO:0051537]; identical protein binding [GO:0042802]; L-cysteine transaminase activity [GO:0047801]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170] | 16949.36031458765 | 0.0706665062705967 | 0.867419674171329 | 1 |
| Q8N5K1 | Q8N5K1 | CISD2_HUMAN | CDGSH iron-sulfur domain-containing protein 2 (Endoplasmic reticulum intermembrane small protein) (MitoNEET-related 1 protein) (Miner1) (Nutrient-deprivation autophagy factor-1) (NAF-1) | CISD2 | autophagy [GO:0006914]; regulation of autophagy [GO:0010506] | endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; perinuclear endoplasmic reticulum [GO:0097038]; protein-containing complex [GO:0032991] | 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723] | 13794.880251982151 | 0.0211916945219084 | 0.993257616125661 | 1 |
| Q07065 | Q07065 | CKAP4_HUMAN | Cytoskeleton-associated protein 4 (63-kDa cytoskeleton-linking membrane protein) (Climp-63) (p63) | CKAP4 | azurophil granule membrane [GO:0035577]; cytoskeleton [GO:0005856]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; lamellar body [GO:0042599]; lipid droplet [GO:0005811]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; rough endoplasmic reticulum [GO:0005791]; specific granule membrane [GO:0035579] | RNA binding [GO:0003723] | 1131380.6840927652 | 0.020812652874758 | 0.999999999342701 | 1 | |
| Q14008 | Q14008 | CKAP5_HUMAN | Cytoskeleton-associated protein 5 (Colonic and hepatic tumor overexpressed gene protein) (Ch-TOG) | CKAP5 | cell division [GO:0051301]; centrosome cycle [GO:0007098]; centrosome duplication [GO:0051298]; establishment or maintenance of microtubule cytoskeleton polarity [GO:0030951]; microtubule depolymerization [GO:0007019]; microtubule polymerization [GO:0046785]; mitotic spindle organization [GO:0007052]; positive regulation of microtubule nucleation [GO:0090063]; RNA transport [GO:0050658]; spindle organization [GO:0007051] | centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; kinetochore [GO:0000776]; membrane [GO:0016020]; microtubule plus-end [GO:0035371]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; spindle pole [GO:0000922] | cadherin binding [GO:0045296]; microtubule binding [GO:0008017]; microtubule plus end polymerase [GO:0061863]; microtubule plus-end binding [GO:0051010]; ribonucleoprotein complex binding [GO:0043021] | 11022.8688120107 | -0.194461079807896 | 0.937930786983734 | 1 |
| Q96S66 | Q96S66 | CLCC1_HUMAN | Chloride channel CLIC-like protein 1 (Mid-1-related chloride channel protein 1) | CLCC1 | chloride channel complex [GO:0034707]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; Golgi membrane [GO:0000139]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondria-associated endoplasmic reticulum membrane [GO:0044233]; nuclear membrane [GO:0031965] | chloride channel activity [GO:0005254] | 12695.89906516635 | 0.0549159707410434 | 0.960143968335906 | 1 | |
| P51790 | P51790 | CLCN3_HUMAN | H(+)/Cl(-) exchange transporter 3 (Chloride channel protein 3) (ClC-3) (Chloride transporter ClC-3) | CLCN3 | adult locomotory behavior [GO:0008344]; chloride transmembrane transport [GO:1902476]; endosomal lumen acidification [GO:0048388]; negative regulation of cell volume [GO:0045794]; phagocytosis, engulfment [GO:0006911]; photoreceptor cell maintenance [GO:0045494]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; regulation of pH [GO:0006885]; synaptic transmission, GABAergic [GO:0051932]; synaptic transmission, glutamatergic [GO:0035249]; synaptic vesicle lumen acidification [GO:0097401] | axon terminus [GO:0043679]; cell surface [GO:0009986]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; external side of plasma membrane [GO:0009897]; GABA-ergic synapse [GO:0098982]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; ruffle membrane [GO:0032587]; secretory granule [GO:0030141]; specific granule [GO:0042581]; synaptic vesicle [GO:0008021]; synaptic vesicle membrane [GO:0030672]; vesicle membrane [GO:0012506] | antiporter activity [GO:0015297]; ATP binding [GO:0005524]; chloride channel activity [GO:0005254]; PDZ domain binding [GO:0030165]; voltage-gated chloride channel activity [GO:0005247]; volume-sensitive chloride channel activity [GO:0072320] | 8022.244257125555 | -0.0319387233975598 | 0.89211131006195 | 1 |
| P51798 | P51798 | CLCN7_HUMAN | H(+)/Cl(-) exchange transporter 7 (Chloride channel 7 alpha subunit) (Chloride channel protein 7) (ClC-7) | CLCN7 | transepithelial chloride transport [GO:0030321] | chloride channel complex [GO:0034707]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal membrane [GO:0005765]; membrane [GO:0016020] | antiporter activity [GO:0015297]; ATP binding [GO:0005524]; chloride channel activity [GO:0005254]; chloride transmembrane transporter activity [GO:0015108]; voltage-gated chloride channel activity [GO:0005247] | 7529.407584394905 | -0.148214238777644 | 0.922526143271949 | 1 |
| Q9Y240 | Q9Y240 | CLC11_HUMAN | C-type lectin domain family 11 member A (C-type lectin superfamily member 3) (Lymphocyte secreted C-type lectin) (Osteolectin) (Stem cell growth factor) (p47) | CLEC11A | ossification [GO:0001503]; positive regulation of cell population proliferation [GO:0008284] | cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615] | carbohydrate binding [GO:0030246]; growth factor activity [GO:0008083] | 12905.6262205603 | 0.0240282889956784 | 0.96235457728258 | 1 |
| Q9NZA1 | Q9NZA1 | CLIC5_HUMAN | Chloride intracellular channel protein 5 | CLIC5 | chloride transport [GO:0006821]; female pregnancy [GO:0007565]; response to stimulus [GO:0050896]; sensory perception of sound [GO:0007605]; visual perception [GO:0007601] | actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; cell cortex [GO:0005938]; centrosome [GO:0005813]; chloride channel complex [GO:0034707]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; mitochondrion [GO:0005739]; stereocilium base [GO:0120044] | chloride channel activity [GO:0005254] | 16293.844697676901 | 0.0605559709366519 | 0.968852557144426 | 1 |
| P30622 | P30622 | CLIP1_HUMAN | CAP-Gly domain-containing linker protein 1 (Cytoplasmic linker protein 1) (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed-Sternberg intermediate filament-associated protein) (Restin) | CLIP1 | cytoplasmic microtubule organization [GO:0031122]; microtubule bundle formation [GO:0001578]; mitotic cell cycle [GO:0000278]; positive regulation of microtubule polymerization [GO:0031116] | cell cortex [GO:0005938]; centrosome [GO:0005813]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; intermediate filament [GO:0005882]; kinetochore [GO:0000776]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; microtubule plus-end [GO:0035371]; nucleus [GO:0005634]; ruffle [GO:0001726] | identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; microtubule plus-end binding [GO:0051010]; tubulin binding [GO:0015631]; zinc ion binding [GO:0008270] | 26543.3371754756 | 0.0479052687822944 | 0.999795213073061 | 1 |
| Q96KA5 | Q96KA5 | CLP1L_HUMAN | Lipid scramblase CLPTM1L (Cisplatin resistance-related protein 9) (CRR9p) (Cleft lip and palate transmembrane protein 1-like protein) (CLPTM1-like protein) | CLPTM1L | apoptotic process [GO:0006915] | endomembrane system [GO:0012505]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020] | phospholipid scramblase activity [GO:0017128] | 19999.4972344166 | -0.0172694799287475 | 0.999999069886234 | 1 |
| O76031 | O76031 | CLPX_HUMAN | ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial | CLPX | ATP metabolic process [GO:0046034]; cell division [GO:0051301]; proteolysis [GO:0006508]; proteolysis involved in protein catabolic process [GO:0051603] | cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; HslUV protease complex [GO:0009376]; mitochondrial endopeptidase Clp complex [GO:0009841]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654] | ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-dependent protein folding chaperone [GO:0140662]; peptidase activator activity [GO:0016504]; protein dimerization activity [GO:0046983]; unfolded protein binding [GO:0051082]; zinc ion binding [GO:0008270] | 7865.436826688745 | -0.0628597928747955 | 0.894102635111064 | 1 |
| O94985 | O94985 | CSTN1_HUMAN | Calsyntenin-1 (Alcadein-alpha) (Alc-alpha) (Alzheimer-related cadherin-like protein) (Non-classical cadherin XB31alpha) [Cleaved into: Soluble Alc-alpha (SAlc-alpha); CTF1-alpha (C-terminal fragment 1-alpha)] | CLSTN1 | cell adhesion [GO:0007155]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurotransmitter receptor transport to postsynaptic membrane [GO:0098969]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic transmission [GO:0050806]; regulation of cell growth [GO:0001558]; regulation of synapse maturation [GO:0090128]; vesicle-mediated transport in synapse [GO:0099003] | cell surface [GO:0009986]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; glutamatergic synapse [GO:0098978]; Golgi membrane [GO:0000139]; neuron projection [GO:0043005]; nucleus [GO:0005634]; postsynaptic density [GO:0014069]; postsynaptic endosome [GO:0098845]; postsynaptic membrane [GO:0045211] | amyloid-beta binding [GO:0001540]; calcium ion binding [GO:0005509]; kinesin binding [GO:0019894]; X11-like protein binding [GO:0042988] | 4972.960564484039 | 0.122116337411804 | 0.811498737966628 | 1 |
| O75153 | O75153 | CLU_HUMAN | Clustered mitochondria protein homolog | CLUH | intracellular distribution of mitochondria [GO:0048312]; mitochondrion organization [GO:0007005] | cytoplasm [GO:0005737] | mRNA binding [GO:0003729] | 5573.708099097625 | -0.108509703576833 | 0.930507722272271 | 1 |
| Q96DG6 | Q96DG6 | CMBL_HUMAN | Carboxymethylenebutenolidase homolog (EC 3.1.-.-) | CMBL | xenobiotic metabolic process [GO:0006805] | cytosol [GO:0005829]; extracellular exosome [GO:0070062] | hydrolase activity [GO:0016787] | 15790.8023741004 | 0.0556838392389852 | 0.815121554924981 | 1 |
| P30085 | P30085 | KCY_HUMAN | UMP-CMP kinase (EC 2.7.4.14) (Deoxycytidylate kinase) (CK) (dCMP kinase) (Nucleoside-diphosphate kinase) (EC 2.7.4.6) (Uridine monophosphate/cytidine monophosphate kinase) (UMP/CMP kinase) (UMP/CMPK) | CMPK1 | 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; CDP biosynthetic process [GO:0046705]; nucleobase-containing small molecule interconversion [GO:0015949]; phosphorylation [GO:0016310]; pyrimidine ribonucleotide biosynthetic process [GO:0009220]; UDP biosynthetic process [GO:0006225] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] | adenylate kinase activity [GO:0004017]; ATP binding [GO:0005524]; CMP kinase activity [GO:0036430]; cytidylate kinase activity [GO:0004127]; dCMP kinase activity [GO:0036431]; nucleoside diphosphate kinase activity [GO:0004550]; nucleoside monophosphate kinase activity [GO:0050145]; UMP kinase activity [GO:0033862]; uridine kinase activity [GO:0004849] | 222018.6427077355 | -0.00367165264161662 | 0.999999999714125 | 1 |
| Q96KP4 | Q96KP4 | CNDP2_HUMAN | Cytosolic non-specific dipeptidase (EC 3.4.13.18) (CNDP dipeptidase 2) (Glutamate carboxypeptidase-like protein 1) (Peptidase A) (Threonyl dipeptidase) | CNDP2 | proteolysis [GO:0006508] | cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654] | alanylglutamate dipeptidase activity [GO:0103046]; carboxypeptidase activity [GO:0004180]; dipeptidase activity [GO:0016805]; metal ion binding [GO:0046872]; metallodipeptidase activity [GO:0070573] | 41659.14392449855 | 0.0142956498420355 | 0.999999886325613 | 1 |
| Q9H9A5 | Q9H9A5 | CNO10_HUMAN | CCR4-NOT transcription complex subunit 10 | CNOT10 | mRNA catabolic process [GO:0006402]; negative regulation of translation [GO:0017148]; nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; regulatory ncRNA-mediated gene silencing [GO:0031047] | CCR4-NOT complex [GO:0030014]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleus [GO:0005634] | 4397.702006363725 | 0.128185082675201 | 0.988652693753856 | 1 | |
| Q9UKZ1 | Q9UKZ1 | CNO11_HUMAN | CCR4-NOT transcription complex subunit 11 | CNOT11 | nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; regulation of translation [GO:0006417]; regulatory ncRNA-mediated gene silencing [GO:0031047] | CCR4-NOT complex [GO:0030014]; cytosol [GO:0005829]; nucleus [GO:0005634] | 5843.807032316865 | -0.0143719452990286 | 0.964571693572609 | 1 | |
| Q9NZN8 | Q9NZN8 | CNOT2_HUMAN | CCR4-NOT transcription complex subunit 2 (CCR4-associated factor 2) | CNOT2 | negative regulation of intracellular estrogen receptor signaling pathway [GO:0033147]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; positive regulation of cytoplasmic mRNA processing body assembly [GO:0010606]; regulation of stem cell population maintenance [GO:2000036]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of translation [GO:0006417]; regulatory ncRNA-mediated gene silencing [GO:0031047]; trophectodermal cell differentiation [GO:0001829] | CCR4-NOT complex [GO:0030014]; CCR4-NOT core complex [GO:0030015]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]; plasma membrane [GO:0005886] | transcription coregulator activity [GO:0003712]; transcription corepressor binding [GO:0001222] | 13638.34636540665 | 0.0607776173973448 | 0.996905197483951 | 1 |
| O75175 | O75175 | CNOT3_HUMAN | CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3) (Leukocyte receptor cluster member 2) | CNOT3 | nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; positive regulation of cold-induced thermogenesis [GO:0120162]; regulation of DNA-templated transcription [GO:0006355]; regulation of stem cell population maintenance [GO:2000036]; regulation of translation [GO:0006417]; regulatory ncRNA-mediated gene silencing [GO:0031047]; trophectodermal cell differentiation [GO:0001829] | CCR4-NOT complex [GO:0030014]; CCR4-NOT core complex [GO:0030015]; cytosol [GO:0005829]; nucleus [GO:0005634]; P-body [GO:0000932] | 16292.5124103907 | 0.0798587883090032 | 0.72999157090857 | 1 | |
| O95628 | O95628 | CNOT4_HUMAN | CCR4-NOT transcription complex subunit 4 (EC 2.3.2.27) (CCR4-associated factor 4) (E3 ubiquitin-protein ligase CNOT4) (Potential transcriptional repressor NOT4Hp) (RING-type E3 ubiquitin transferase CNOT4) | CNOT4 | nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; protein autoubiquitination [GO:0051865]; protein ubiquitination [GO:0016567]; regulation of megakaryocyte differentiation [GO:0045652]; ubiquitin-dependent protein catabolic process [GO:0006511] | CCR4-NOT complex [GO:0030014]; cytosol [GO:0005829]; nucleus [GO:0005634] | metal ion binding [GO:0046872]; RNA binding [GO:0003723]; ubiquitin-protein transferase activity [GO:0004842] | 9001.24053218625 | 0.0798711753998059 | 0.778725263206248 | 1 |
| Q9UIV1 | Q9UIV1 | CNOT7_HUMAN | CCR4-NOT transcription complex subunit 7 (EC 3.1.13.4) (BTG1-binding factor 1) (CCR4-associated factor 1) (CAF-1) (Caf1a) | CNOT7 | deadenylation-dependent decapping of nuclear-transcribed mRNA [GO:0000290]; defense response to virus [GO:0051607]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; miRNA-mediated post-transcriptional gene silencing [GO:0035195]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of gene expression [GO:0010629]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; P-body assembly [GO:0033962]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of mRNA catabolic process [GO:0061014]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of viral genome replication [GO:0045070]; regulation of translation [GO:0006417]; regulation of tyrosine phosphorylation of STAT protein [GO:0042509]; regulatory ncRNA-mediated gene silencing [GO:0031047] | CCR4-NOT complex [GO:0030014]; CCR4-NOT core complex [GO:0030015]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular non-membrane-bounded organelle [GO:0043232]; membrane [GO:0016020]; nuclear body [GO:0016604]; nuclear speck [GO:0016607]; nucleus [GO:0005634]; P-body [GO:0000932] | 3'-5'-RNA exonuclease activity [GO:0000175]; DNA-binding transcription factor binding [GO:0140297]; metal ion binding [GO:0046872]; poly(A)-specific ribonuclease activity [GO:0004535]; RNA binding [GO:0003723]; RNA exonuclease activity [GO:0004532]; transcription corepressor activity [GO:0003714] | 9845.89027293555 | -0.154386275079104 | 0.854905765100428 | 1 |
| P09543 | P09543 | CN37_HUMAN | 2',3'-cyclic-nucleotide 3'-phosphodiesterase (CNP) (CNPase) (EC 3.1.4.37) | CNP | adult locomotory behavior [GO:0008344]; axonogenesis [GO:0007409]; chemical synaptic transmission [GO:0007268]; cyclic nucleotide catabolic process [GO:0009214]; forebrain development [GO:0030900]; oligodendrocyte differentiation [GO:0048709]; regulation of mitochondrial membrane permeability [GO:0046902]; response to lipopolysaccharide [GO:0032496]; response to toxic substance [GO:0009636]; substantia nigra development [GO:0021762] | cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; melanosome [GO:0042470]; membrane [GO:0016020]; microtubule [GO:0005874]; microvillus [GO:0005902]; mitochondrial inner membrane [GO:0005743]; mitochondrial outer membrane [GO:0005741]; myelin sheath abaxonal region [GO:0035748]; myelin sheath adaxonal region [GO:0035749]; perinuclear region of cytoplasm [GO:0048471]; pseudopodium [GO:0031143]; synapse [GO:0045202] | 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity [GO:0004113]; cyclic nucleotide binding [GO:0030551]; RNA binding [GO:0003723] | 34130.60487297405 | 0.0450705248896481 | 0.991826727840642 | 1 |
| Q96F85 | Q96F85 | CNRP1_HUMAN | CB1 cannabinoid receptor-interacting protein 1 (CRIP-1) | CNRIP1 | negative regulation of signaling receptor activity [GO:2000272]; regulation of signaling receptor activity [GO:0010469] | cytoplasm [GO:0005737]; plasma membrane [GO:0005886] | type 1 cannabinoid receptor binding [GO:0031718] | 35908.26987176035 | -0.0153371856571335 | 0.999977705177712 | 1 |
| Q53SF7 | Q53SF7 | COBL1_HUMAN | Cordon-bleu protein-like 1 | COBLL1 | extracellular exosome [GO:0070062] | actin monomer binding [GO:0003785]; cadherin binding [GO:0045296] | 4419.654000897795 | 0.0199471907596433 | 0.999800465344828 | 1 | |
| Q9Y2V7 | Q9Y2V7 | COG6_HUMAN | Conserved oligomeric Golgi complex subunit 6 (COG complex subunit 6) (Component of oligomeric Golgi complex 6) | COG6 | glycosylation [GO:0070085]; Golgi organization [GO:0007030]; intra-Golgi vesicle-mediated transport [GO:0006891]; protein transport [GO:0015031]; retrograde transport, vesicle recycling within Golgi [GO:0000301] | Golgi membrane [GO:0000139]; Golgi transport complex [GO:0017119]; trans-Golgi network membrane [GO:0032588] | 11461.72566661315 | 0.0299427211653872 | 0.999976614753753 | 1 | |
| P83436 | P83436 | COG7_HUMAN | Conserved oligomeric Golgi complex subunit 7 (COG complex subunit 7) (Component of oligomeric Golgi complex 7) | COG7 | glycosylation [GO:0070085]; Golgi organization [GO:0007030]; intracellular protein transport [GO:0006886]; protein glycosylation [GO:0006486]; protein localization to Golgi apparatus [GO:0034067]; protein localization to organelle [GO:0033365]; protein stabilization [GO:0050821]; retrograde transport, vesicle recycling within Golgi [GO:0000301]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890] | Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; Golgi transport complex [GO:0017119]; intracellular membrane-bounded organelle [GO:0043231]; nucleolus [GO:0005730]; trans-Golgi network membrane [GO:0032588] | 8382.356104091985 | -0.108039119326412 | 0.956788339079754 | 1 | |
| Q96MW5 | Q96MW5 | COG8_HUMAN | Conserved oligomeric Golgi complex subunit 8 (COG complex subunit 8) (Component of oligomeric Golgi complex 8) | COG8 | glycosylation [GO:0070085]; Golgi organization [GO:0007030]; intra-Golgi vesicle-mediated transport [GO:0006891]; protein transport [GO:0015031]; retrograde transport, vesicle recycling within Golgi [GO:0000301] | Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; Golgi transport complex [GO:0017119]; membrane [GO:0016020]; trans-Golgi network membrane [GO:0032588] | 5574.2295155097145 | 0.0588542398984864 | 0.997358563374575 | 1 | |
| P02458 | P02458 | CO2A1_HUMAN | Collagen alpha-1(II) chain (Alpha-1 type II collagen) [Cleaved into: Collagen alpha-1(II) chain; Chondrocalcin] | COL2A1 | anterior head development [GO:0097065]; cartilage condensation [GO:0001502]; cartilage development [GO:0051216]; cartilage development involved in endochondral bone morphogenesis [GO:0060351]; cellular response to BMP stimulus [GO:0071773]; central nervous system development [GO:0007417]; chondrocyte differentiation [GO:0002062]; collagen fibril organization [GO:0030199]; embryonic skeletal joint morphogenesis [GO:0060272]; endochondral ossification [GO:0001958]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; heart morphogenesis [GO:0003007]; inner ear morphogenesis [GO:0042472]; limb bud formation [GO:0060174]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; notochord development [GO:0030903]; otic vesicle development [GO:0071599]; proteoglycan metabolic process [GO:0006029]; regulation of gene expression [GO:0010468]; roof of mouth development [GO:0060021]; sensory perception of sound [GO:0007605]; skeletal system development [GO:0001501]; tissue homeostasis [GO:0001894]; visual perception [GO:0007601] | basement membrane [GO:0005604]; collagen type II trimer [GO:0005585]; collagen type XI trimer [GO:0005592]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615] | extracellular matrix structural constituent conferring tensile strength [GO:0030020]; metal ion binding [GO:0046872]; MHC class II protein binding [GO:0042289]; platelet-derived growth factor binding [GO:0048407]; protein homodimerization activity [GO:0042803]; proteoglycan binding [GO:0043394] | 63552.6545745645 | -0.445306550515382 | 0.940901681671089 | 1 |
| P12110 | P12110 | CO6A2_HUMAN | Collagen alpha-2(VI) chain | COL6A2 | cell adhesion [GO:0007155]; neuron apoptotic process [GO:0051402]; phosphatidylinositol 3-kinase/protein kinase B signal transduction [GO:0043491]; response to glucose [GO:0009749]; response to UV [GO:0009411] | collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extracellular vesicle [GO:1903561]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383] | collagen binding [GO:0005518]; extracellular matrix structural constituent conferring tensile strength [GO:0030020] | 67497.74102927139 | -0.0432504726270556 | 0.987644214552913 | 1 |
| Q8NBJ5 | Q8NBJ5 | GT251_HUMAN | Procollagen galactosyltransferase 1 (EC 2.4.1.50) (Collagen beta(1-O)galactosyltransferase 1) (ColGalT 1) (Glycosyltransferase 25 family member 1) (Hydroxylysine galactosyltransferase 1) | COLGALT1 | collagen fibril organization [GO:0030199]; positive regulation of collagen fibril organization [GO:1904028] | endoplasmic reticulum lumen [GO:0005788]; membrane [GO:0016020] | procollagen galactosyltransferase activity [GO:0050211] | 96359.09383671745 | 0.0640198818359806 | 0.931099044879541 | 1 |
| Q86X83 | Q86X83 | COMD2_HUMAN | COMM domain-containing protein 2 | COMMD2 | cytoplasm [GO:0005737] | 12024.5233609758 | -0.0126687520256035 | 0.999559353410389 | 1 | ||
| Q9UBI1 | Q9UBI1 | COMD3_HUMAN | COMM domain-containing protein 3 (Protein Bup) (Protein PIL) | COMMD3 | sodium ion transport [GO:0006814] | extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634] | 8137.622177687555 | -0.123517141179634 | 0.705692002382237 | 1 | |
| Q9UBF2 | Q9UBF2 | COPG2_HUMAN | Coatomer subunit gamma-2 (Gamma-2-coat protein) (Gamma-2-COP) | COPG2 | endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intra-Golgi vesicle-mediated transport [GO:0006891]; intracellular protein transport [GO:0006886]; organelle transport along microtubule [GO:0072384]; protein secretion [GO:0009306]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890] | COPI vesicle coat [GO:0030126]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; Golgi membrane [GO:0000139]; growth cone [GO:0030426]; transport vesicle [GO:0030133] | structural molecule activity [GO:0005198] | 13127.01714518425 | -0.129924354260508 | 0.697873544267237 | 1 |
| P61201 | P61201 | CSN2_HUMAN | COP9 signalosome complex subunit 2 (SGN2) (Signalosome subunit 2) (Alien homolog) (JAB1-containing signalosome subunit 2) (Thyroid receptor-interacting protein 15) (TR-interacting protein 15) (TRIP-15) | COPS2 | inner cell mass cell proliferation [GO:0001833]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron differentiation [GO:0030182]; protein deneddylation [GO:0000338]; protein neddylation [GO:0045116]; protein phosphorylation [GO:0006468]; regulation of protein neddylation [GO:2000434]; signal transduction [GO:0007165]; skeletal muscle cell differentiation [GO:0035914]; transcription by RNA polymerase II [GO:0006366]; trophectodermal cell proliferation [GO:0001834] | COP9 signalosome [GO:0008180]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] | transcription corepressor activity [GO:0003714] | 32012.11833804125 | 0.0157311253128751 | 0.999999764258522 | 1 |
| Q9UNS2 | Q9UNS2 | CSN3_HUMAN | COP9 signalosome complex subunit 3 (SGN3) (Signalosome subunit 3) (JAB1-containing signalosome subunit 3) | COPS3 | in utero embryonic development [GO:0001701]; protein deneddylation [GO:0000338]; protein neddylation [GO:0045116]; regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:1902162]; regulation of protein neddylation [GO:2000434]; response to light stimulus [GO:0009416]; signal transduction [GO:0007165]; ubiquitin-dependent protein catabolic process [GO:0006511] | COP9 signalosome [GO:0008180]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471] | 23573.5779982554 | 0.0240700559234491 | 0.999967922795776 | 1 | |
| Q9H9Q2 | Q9H9Q2 | CSN7B_HUMAN | COP9 signalosome complex subunit 7b (SGN7b) (Signalosome subunit 7b) (JAB1-containing signalosome subunit 7b) | COPS7B | COP9 signalosome assembly [GO:0010387]; protein deneddylation [GO:0000338]; regulation of protein neddylation [GO:2000434] | COP9 signalosome [GO:0008180]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] | 7625.38104503174 | -0.00148347503431008 | 0.989840248170222 | 1 | |
| Q9ULV4 | Q9ULV4 | COR1C_HUMAN | Coronin-1C (Coronin-3) (hCRNN4) | CORO1C | actin filament organization [GO:0007015]; activation of GTPase activity [GO:0090630]; corpus callosum development [GO:0022038]; endosomal transport [GO:0016197]; endosome fission [GO:0140285]; endosome membrane tubulation [GO:0097750]; establishment of protein localization [GO:0045184]; membrane fission [GO:0090148]; negative regulation of epithelial cell migration [GO:0010633]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of protein kinase activity by regulation of protein phosphorylation [GO:0044387]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of substrate adhesion-dependent cell spreading [GO:1900025]; neural crest cell migration [GO:0001755]; phagocytosis [GO:0006909]; positive regulation of lamellipodium morphogenesis [GO:2000394]; regulation of epithelial cell migration [GO:0010632]; regulation of fibroblast migration [GO:0010762]; regulation of focal adhesion assembly [GO:0051893]; regulation of protein phosphorylation [GO:0001932]; regulation of ruffle assembly [GO:1900027]; regulation of substrate adhesion-dependent cell spreading [GO:1900024]; signal transduction [GO:0007165]; ventricular system development [GO:0021591] | actin cytoskeleton [GO:0015629]; cell cortex [GO:0005938]; endosome membrane [GO:0010008]; flotillin complex [GO:0016600]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; lateral plasma membrane [GO:0016328]; ruffle membrane [GO:0032587]; sarcolemma [GO:0042383]; sarcomere [GO:0030017]; synapse [GO:0045202] | actin filament binding [GO:0051015]; small GTPase binding [GO:0031267] | 98717.58009413886 | 0.0802674822281066 | 0.956390658472712 | 1 |
| P10606 | P10606 | COX5B_HUMAN | Cytochrome c oxidase subunit 5B, mitochondrial (Cytochrome c oxidase polypeptide Vb) | COX5B | cellular respiration [GO:0045333]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; respiratory gaseous exchange by respiratory system [GO:0007585] | mitochondrial inner membrane [GO:0005743]; mitochondrial membrane [GO:0031966]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739] | cytochrome-c oxidase activity [GO:0004129]; metal ion binding [GO:0046872] | 42663.68017259585 | -0.00533597755630508 | 0.99994491099657 | 1 |
| Q99829 | Q99829 | CPNE1_HUMAN | Copine-1 (Chromobindin 17) (Copine I) | CPNE1 | cellular response to calcium ion [GO:0071277]; lipid metabolic process [GO:0006629]; negative regulation of DNA binding [GO:0043392]; negative regulation of gene expression [GO:0010629]; negative regulation of non-canonical NF-kappaB signal transduction [GO:1901223]; neuron projection extension [GO:1990138]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction [GO:0051897]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; proteolysis [GO:0006508]; regulation of canonical NF-kappaB signal transduction [GO:0043122]; vesicle-mediated transport [GO:0016192] | azurophil granule membrane [GO:0035577]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886] | calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]; endopeptidase activity [GO:0004175]; identical protein binding [GO:0042802]; NF-kappaB binding [GO:0051059]; phosphatidylserine binding [GO:0001786] | 38395.0089920353 | -0.0287036982855623 | 0.989124224970493 | 1 |
| Q86YQ8 | Q86YQ8 | CPNE8_HUMAN | Copine-8 (Copine VIII) | CPNE8 | cellular response to calcium ion [GO:0071277] | extracellular exosome [GO:0070062]; plasma membrane [GO:0005886] | calcium-dependent phospholipid binding [GO:0005544]; metal ion binding [GO:0046872] | 22798.40810594435 | 0.00135573171749071 | 0.998297394333205 | 1 |
| Q9Y646 | Q9Y646 | CBPQ_HUMAN | Carboxypeptidase Q (EC 3.4.17.-) (Lysosomal dipeptidase) (Plasma glutamate carboxypeptidase) | CPQ | peptide catabolic process [GO:0043171]; proteolysis [GO:0006508]; thyroid hormone generation [GO:0006590]; tissue regeneration [GO:0042246] | cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; lysosome [GO:0005764] | carboxypeptidase activity [GO:0004180]; metal ion binding [GO:0046872]; metallodipeptidase activity [GO:0070573]; protein homodimerization activity [GO:0042803] | 30327.674038975798 | 0.0302288188918992 | 0.989646157541252 | 1 |
| Q16630 | Q16630 | CPSF6_HUMAN | Cleavage and polyadenylation specificity factor subunit 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Cleavage factor Im complex 68 kDa subunit) (CFIm68) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII-4/7) | CPSF6 | localization [GO:0051179]; messenger ribonucleoprotein complex assembly [GO:1990120]; mRNA 3'-end processing [GO:0031124]; mRNA alternative polyadenylation [GO:0110104]; mRNA processing [GO:0006397]; positive regulation of RNA export from nucleus [GO:0046833]; protein heterotetramerization [GO:0051290]; protein tetramerization [GO:0051262] | cytoplasm [GO:0005737]; interchromatin granule [GO:0035061]; membrane [GO:0016020]; mRNA cleavage and polyadenylation specificity factor complex [GO:0005847]; mRNA cleavage factor complex [GO:0005849]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; paraspeckles [GO:0042382]; perichromatin fibrils [GO:0005726]; ribonucleoprotein complex [GO:1990904] | exon-exon junction complex binding [GO:1990448]; mRNA binding [GO:0003729]; ribosomal large subunit binding [GO:0043023]; RNA binding [GO:0003723] | 21587.74398174925 | -0.0225483814186403 | 0.999953763194086 | 1 |
| P23786 | P23786 | CPT2_HUMAN | Carnitine O-palmitoyltransferase 2, mitochondrial (EC 2.3.1.21) (Carnitine palmitoyltransferase II) (CPT II) | CPT2 | carnitine metabolic process [GO:0009437]; carnitine shuttle [GO:0006853]; fatty acid beta-oxidation [GO:0006635]; in utero embryonic development [GO:0001701]; long-chain fatty acid metabolic process [GO:0001676]; positive regulation of cold-induced thermogenesis [GO:0120162] | mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654] | acyltransferase activity [GO:0016746]; carnitine O-octanoyltransferase activity [GO:0008458]; carnitine O-palmitoyltransferase activity [GO:0004095] | 7078.725009652369 | 0.076250946519506 | 0.96326879287162 | 1 |
| P43155 | P43155 | CACP_HUMAN | Carnitine O-acetyltransferase (Carnitine acetylase) (EC 2.3.1.137) (EC 2.3.1.7) (Carnitine acetyltransferase) (CAT) (CrAT) | CRAT | carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; medium-chain fatty acid metabolic process [GO:0051791]; short-chain fatty acid metabolic process [GO:0046459] | cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777] | acyl-CoA oxidase activity [GO:0003997]; carnitine O-acetyltransferase activity [GO:0004092]; carnitine O-octanoyltransferase activity [GO:0008458] | 7400.62539614099 | -0.0733288123729064 | 0.751117526409046 | 1 |
| P16220 | P16220 | CREB1_HUMAN | Cyclic AMP-responsive element-binding protein 1 (CREB-1) (cAMP-responsive element-binding protein 1) | CREB1 | axonogenesis [GO:0007409]; cAMP-mediated signaling [GO:0019933]; cellular response to forskolin [GO:1904322]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to leukemia inhibitory factor [GO:1990830]; cellular response to retinoic acid [GO:0071300]; cellular response to zinc ion [GO:0071294]; circadian rhythm [GO:0007623]; hormone secretion [GO:0046879]; lactation [GO:0007595]; lung saccule development [GO:0060430]; memory [GO:0007613]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by competitive promoter binding [GO:0010944]; osteoclast differentiation [GO:0030316]; pituitary gland development [GO:0021983]; positive regulation of cardiac muscle tissue development [GO:0055025]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of hormone secretion [GO:0046887]; positive regulation of lipid biosynthetic process [GO:0046889]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; regulation of cell size [GO:0008361]; regulation of testosterone biosynthetic process [GO:2000224]; regulation of transcription by RNA polymerase II [GO:0006357]; response to glucagon [GO:0033762]; response to organic substance [GO:0010033]; response to purine-containing compound [GO:0014074]; response to xenobiotic stimulus [GO:0009410]; secretory granule organization [GO:0033363]; signal transduction [GO:0007165]; type I pneumocyte differentiation [GO:0060509] | ATF4-CREB1 transcription factor complex [GO:1990589]; chromatin [GO:0000785]; euchromatin [GO:0000791]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase II transcription regulator complex [GO:0090575] | cAMP response element binding [GO:0035497]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; sequence-specific double-stranded DNA binding [GO:1990837] | 26235.804427078998 | 0.113710936392441 | 0.658845151073197 | 1 |
| Q96BA8 | Q96BA8 | CR3L1_HUMAN | Cyclic AMP-responsive element-binding protein 3-like protein 1 (cAMP-responsive element-binding protein 3-like protein 1) (Old astrocyte specifically-induced substance) (OASIS) [Cleaved into: Processed cyclic AMP-responsive element-binding protein 3-like protein 1] | CREB3L1 | endoplasmic reticulum unfolded protein response [GO:0030968]; extracellular matrix constituent secretion [GO:0070278]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of fibroblast growth factor receptor signaling pathway [GO:0040037]; negative regulation of gene expression [GO:0010629]; negative regulation of sprouting angiogenesis [GO:1903671]; osteoblast differentiation [GO:0001649]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; response to endoplasmic reticulum stress [GO:0034976] | chromatin [GO:0000785]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] | cAMP response element binding [GO:0035497]; chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; sequence-specific double-stranded DNA binding [GO:1990837]; SMAD binding [GO:0046332]; transcription cis-regulatory region binding [GO:0000976] | 9464.524793755976 | 0.175191702041175 | 0.908127901550968 | 1 |
| P52943 | P52943 | CRIP2_HUMAN | Cysteine-rich protein 2 (CRP-2) (Protein ESP1) | CRIP2 | hemopoiesis [GO:0030097]; positive regulation of cell population proliferation [GO:0008284] | cell cortex [GO:0005938] | zinc ion binding [GO:0008270] | 89058.5291968212 | -0.0775206162148414 | 0.992593043974831 | 1 |
| Q9BZJ0 | Q9BZJ0 | CRNL1_HUMAN | Crooked neck-like protein 1 (Crooked neck homolog) (hCrn) | CRNKL1 | mRNA splicing, via spliceosome [GO:0000398]; spliceosomal complex assembly [GO:0000245] | catalytic step 2 spliceosome [GO:0071013]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; post-mRNA release spliceosomal complex [GO:0071014]; precatalytic spliceosome [GO:0071011]; Prp19 complex [GO:0000974]; spliceosomal complex [GO:0005681]; U2-type catalytic step 2 spliceosome [GO:0071007] | RNA binding [GO:0003723] | 6493.580322232535 | 0.171157043262715 | 0.857165765251619 | 1 |
| Q6UUV9 | Q6UUV9 | CRTC1_HUMAN | CREB-regulated transcription coactivator 1 (Mucoepidermoid carcinoma translocated protein 1) (Transducer of regulated cAMP response element-binding protein 1) (TORC-1) (Transducer of CREB protein 1) | CRTC1 | energy homeostasis [GO:0097009]; entrainment of circadian clock by photoperiod [GO:0043153]; memory [GO:0007613]; negative regulation of membrane hyperpolarization [GO:1902631]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein homotetramerization [GO:0051289]; rhythmic process [GO:0048511] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886] | cAMP response element binding protein binding [GO:0008140] | 13018.8640493649 | -0.0203037534898266 | 0.993572858885617 | 1 |
| Q68DQ2 | Q68DQ2 | CRBG3_HUMAN | Very large A-kinase anchor protein (vlAKAP) (Beta/gamma crystallin domain-containing protein 3) | CRYBG3 | lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601] | protein-containing complex [GO:0032991] | carbohydrate binding [GO:0030246]; protein kinase A binding [GO:0051018]; structural constituent of eye lens [GO:0005212] | 4371.375065251095 | -0.121235780048822 | 0.980244504029494 | 1 |
| O95825 | O95825 | QORL1_HUMAN | Quinone oxidoreductase-like protein 1 (EC 1.-.-.-) (Ferry endosomal RAB5 effector complex subunit 4) (Fy-4) (Protein 4P11) (Quinone oxidoreductase homolog 1) (QOH-1) (Zeta-crystallin homolog) | CRYZL1 | quinone metabolic process [GO:1901661] | cytosol [GO:0005829]; early endosome [GO:0005769] | NADP binding [GO:0050661]; NADPH:quinone reductase activity [GO:0003960] | 8233.134972921425 | 0.0667733837402357 | 0.998968218969499 | 1 |
| O75390 | O75390 | CISY_HUMAN | Citrate synthase, mitochondrial (EC 2.3.3.1) (Citrate (Si)-synthase) | CS | carbohydrate metabolic process [GO:0005975]; citrate metabolic process [GO:0006101]; tricarboxylic acid cycle [GO:0006099] | extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634] | citrate (Si)-synthase activity [GO:0004108]; RNA binding [GO:0003723] | 24374.9187519131 | 0.0190322566001053 | 0.99996375338039 | 1 |
| O75534 | O75534 | CSDE1_HUMAN | Cold shock domain-containing protein E1 (N-ras upstream gene protein) (Protein UNR) | CSDE1 | CRD-mediated mRNA stabilization [GO:0070934]; IRES-dependent viral translational initiation [GO:0075522]; male gonad development [GO:0008584]; negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900152]; nuclear-transcribed mRNA catabolic process, no-go decay [GO:0070966]; positive regulation of cytoplasmic translation [GO:2000767]; regulation of translational initiation [GO:0006446]; stress granule assembly [GO:0034063] | CRD-mediated mRNA stability complex [GO:0070937]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; mCRD-mediated mRNA stability complex [GO:0106002]; P-body [GO:0000932]; plasma membrane [GO:0005886] | RISC complex binding [GO:1905172]; RNA binding [GO:0003723]; RNA stem-loop binding [GO:0035613] | 34727.6428072665 | 0.0334817517033559 | 0.999361880517667 | 1 |
| P55060 | P55060 | XPO2_HUMAN | Exportin-2 (Exp2) (Cellular apoptosis susceptibility protein) (Chromosome segregation 1-like protein) (Importin-alpha re-exporter) | CSE1L | protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nuclear envelope [GO:0005635]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] | nuclear export signal receptor activity [GO:0005049]; small GTPase binding [GO:0031267] | 19569.605078271 | -0.085941863467405 | 0.996464997214842 | 1 |
| Q8N6G5 | Q8N6G5 | CGAT2_HUMAN | Chondroitin sulfate N-acetylgalactosaminyltransferase 2 (EC 2.4.1.174) (Chondroitin beta-1,4-N-acetylgalactosaminyltransferase 2) (Beta4GalNAcT-2) (GalNAcT-2) | CSGALNACT2 | chondroitin sulfate biosynthetic process [GO:0030206]; chondroitin sulfate proteoglycan biosynthetic process [GO:0050650]; chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process [GO:0050653]; dermatan sulfate proteoglycan biosynthetic process [GO:0050651]; dermatan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process [GO:0050652]; proteoglycan biosynthetic process [GO:0030166] | Golgi cisterna membrane [GO:0032580]; Golgi membrane [GO:0000139]; membrane [GO:0016020] | acetylgalactosaminyltransferase activity [GO:0008376]; glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity [GO:0047238]; glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity [GO:0047237]; metal ion binding [GO:0046872] | 3964.92089856962 | -0.182590949410036 | 0.662665087632874 | 1 |
| P41240 | P41240 | CSK_HUMAN | Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-Src kinase) (Protein-tyrosine kinase CYL) | CSK | adaptive immune response [GO:0002250]; adherens junction organization [GO:0034332]; cellular response to peptide hormone stimulus [GO:0071375]; negative regulation of bone resorption [GO:0045779]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of Golgi to plasma membrane protein transport [GO:0042997]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of low-density lipoprotein particle clearance [GO:0010989]; negative regulation of phagocytosis [GO:0050765]; oligodendrocyte differentiation [GO:0048709]; protein phosphorylation [GO:0006468]; regulation of Fc receptor mediated stimulatory signaling pathway [GO:0060368]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852] | cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; plasma membrane [GO:0005886] | ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; proline-rich region binding [GO:0070064]; protein kinase A catalytic subunit binding [GO:0034236]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; protein tyrosine kinase binding [GO:1990782] | 20448.6846336316 | -0.0219715572877747 | 0.99997194000108 | 1 |
| P48730 | P48730 | KC1D_HUMAN | Casein kinase I isoform delta (CKI-delta) (CKId) (EC 2.7.11.1) (Tau-protein kinase CSNK1D) (EC 2.7.11.26) | CSNK1D | cellular response to nerve growth factor stimulus [GO:1990090]; circadian regulation of gene expression [GO:0032922]; COPII vesicle coating [GO:0048208]; endocytosis [GO:0006897]; Golgi organization [GO:0007030]; microtubule nucleation [GO:0007020]; midbrain dopaminergic neuron differentiation [GO:1904948]; non-motile cilium assembly [GO:1905515]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of non-canonical Wnt signaling pathway [GO:2000052]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein phosphorylation [GO:0001934]; protein localization to centrosome [GO:0071539]; protein localization to cilium [GO:0061512]; protein localization to Golgi apparatus [GO:0034067]; protein phosphorylation [GO:0006468]; regulation of circadian rhythm [GO:0042752]; signal transduction [GO:0007165]; spindle assembly [GO:0051225]; Wnt signaling pathway [GO:0016055] | centrosome [GO:0005813]; ciliary basal body [GO:0036064]; cytosol [GO:0005829]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; Golgi apparatus [GO:0005794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; spindle [GO:0005819]; spindle microtubule [GO:0005876] | ATP binding [GO:0005524]; cadherin binding [GO:0045296]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; tau-protein kinase activity [GO:0050321] | 17273.82016557 | 0.0307013293290407 | 0.980134304517901 | 1 |
| P49674 | P49674 | KC1E_HUMAN | Casein kinase I isoform epsilon (CKI-epsilon) (CKIe) (EC 2.7.11.1) | CSNK1E | canonical Wnt signaling pathway [GO:0060070]; cellular response to nerve growth factor stimulus [GO:1990090]; circadian behavior [GO:0048512]; circadian regulation of gene expression [GO:0032922]; DNA repair [GO:0006281]; endocytosis [GO:0006897]; negative regulation of protein binding [GO:0032091]; negative regulation of Wnt signaling pathway [GO:0030178]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of non-canonical Wnt signaling pathway [GO:2000052]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein localization [GO:0008104]; protein phosphorylation [GO:0006468]; regulation of circadian rhythm [GO:0042752]; regulation of protein localization [GO:0032880]; signal transduction [GO:0007165] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; growth cone [GO:0030426]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904] | ATP binding [GO:0005524]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; RNA binding [GO:0003723] | 19206.73983804515 | 0.0345555093453855 | 0.756094126329063 | 1 |
| P78368;Q9Y6M4 | P78368 | KC1G2_HUMAN | Casein kinase I isoform gamma-2 (CKI-gamma 2) (EC 2.7.11.1) | CSNK1G2 | endocytosis [GO:0006897]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; protein phosphorylation [GO:0006468]; signal transduction [GO:0007165]; sphingolipid biosynthetic process [GO:0030148]; Wnt signaling pathway [GO:0016055] | cell cortex [GO:0005938]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886] | ATP binding [GO:0005524]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] | 8097.551186255965 | 0.00236026850404285 | 0.999999999977798 | 1 |
| P01034 | P01034 | CYTC_HUMAN | Cystatin-C (Cystatin-3) (Gamma-trace) (Neuroendocrine basic polypeptide) (Post-gamma-globulin) | CST3 | defense response [GO:0006952]; negative regulation of blood vessel remodeling [GO:0060313]; negative regulation of collagen catabolic process [GO:0010711]; negative regulation of elastin catabolic process [GO:0060311]; negative regulation of extracellular matrix disassembly [GO:0010716]; negative regulation of peptidase activity [GO:0010466]; negative regulation of proteolysis [GO:0045861]; regulation of tissue remodeling [GO:0034103]; supramolecular fiber organization [GO:0097435] | cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886]; tertiary granule lumen [GO:1904724]; vesicle [GO:0031982] | amyloid-beta binding [GO:0001540]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; endopeptidase inhibitor activity [GO:0004866]; identical protein binding [GO:0042802]; peptidase inhibitor activity [GO:0030414]; protease binding [GO:0002020] | 47107.60035317765 | -0.0136589679941436 | 0.985521422142682 | 1 |
| P01040 | P01040 | CYTA_HUMAN | Cystatin-A (Cystatin-AS) (Stefin-A) [Cleaved into: Cystatin-A, N-terminally processed] | CSTA | cell-cell adhesion [GO:0098609]; keratinocyte differentiation [GO:0030216]; negative regulation of peptidase activity [GO:0010466]; negative regulation of proteolysis [GO:0045861]; peptide cross-linking [GO:0018149] | cornified envelope [GO:0001533]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleoplasm [GO:0005654]; peptidase inhibitor complex [GO:1904090] | cysteine-type endopeptidase inhibitor activity [GO:0004869]; protease binding [GO:0002020] | 32982.854813500846 | -0.0631041049513421 | 0.961107268049755 | 1 |
| P04080 | P04080 | CYTB_HUMAN | Cystatin-B (CPI-B) (Liver thiol proteinase inhibitor) (Stefin-B) | CSTB | adult locomotory behavior [GO:0008344]; negative regulation of peptidase activity [GO:0010466]; negative regulation of proteolysis [GO:0045861] | collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleolus [GO:0005730]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; tertiary granule lumen [GO:1904724] | cysteine-type endopeptidase inhibitor activity [GO:0004869]; endopeptidase inhibitor activity [GO:0004866]; protease binding [GO:0002020]; RNA binding [GO:0003723] | 320523.234485748 | -0.0787301329420467 | 0.84410619403858 | 1 |
| Q05048 | Q05048 | CSTF1_HUMAN | Cleavage stimulation factor subunit 1 (CF-1 50 kDa subunit) (Cleavage stimulation factor 50 kDa subunit) (CSTF 50 kDa subunit) (CstF-50) | CSTF1 | mRNA 3'-end processing [GO:0031124] | mRNA cleavage stimulating factor complex [GO:0005848]; nucleoplasm [GO:0005654] | RNA binding [GO:0003723] | 9759.357451543385 | -0.0541601431588951 | 0.914555757615066 | 1 |
| P33240 | P33240 | CSTF2_HUMAN | Cleavage stimulation factor subunit 2 (CF-1 64 kDa subunit) (Cleavage stimulation factor 64 kDa subunit) (CSTF 64 kDa subunit) (CstF-64) | CSTF2 | cellular response to nerve growth factor stimulus [GO:1990090]; mRNA 3'-end processing [GO:0031124] | cleavage body [GO:0071920]; mRNA cleavage and polyadenylation specificity factor complex [GO:0005847]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654] | mRNA binding [GO:0003729]; RNA binding [GO:0003723] | 14110.49895527895 | 0.080581449969765 | 0.742978950634668 | 1 |
| Q12996 | Q12996 | CSTF3_HUMAN | Cleavage stimulation factor subunit 3 (CF-1 77 kDa subunit) (Cleavage stimulation factor 77 kDa subunit) (CSTF 77 kDa subunit) (CstF-77) | CSTF3 | co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway [GO:0180010]; RNA 3'-end processing [GO:0031123] | mRNA cleavage stimulating factor complex [GO:0005848]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] | mRNA binding [GO:0003729]; RNA binding [GO:0003723] | 9396.508437971315 | 0.125657048769191 | 0.984086764547977 | 1 |
| Q01459 | Q01459 | DIAC_HUMAN | Di-N-acetylchitobiase (EC 3.2.1.-) | CTBS | chitin catabolic process [GO:0006032]; oligosaccharide catabolic process [GO:0009313] | extracellular space [GO:0005615]; lysosome [GO:0005764] | chitin binding [GO:0008061]; chitinase activity [GO:0004568] | 43922.5533807178 | -0.0287972803119556 | 0.95338988449735 | 1 |
| P32929 | P32929 | CGL_HUMAN | Cystathionine gamma-lyase (CGL) (CSE) (EC 4.4.1.1) (Cysteine desulfhydrase) (Cysteine-protein sulfhydrase) (Gamma-cystathionase) (Homocysteine desulfhydrase) (EC 4.4.1.2) | CTH | cellular response to leukemia inhibitory factor [GO:1990830]; cysteine biosynthetic process [GO:0019344]; cysteine biosynthetic process via cystathionine [GO:0019343]; cysteine metabolic process [GO:0006534]; endoplasmic reticulum unfolded protein response [GO:0030968]; hydrogen sulfide biosynthetic process [GO:0070814]; lipid metabolic process [GO:0006629]; negative regulation of apoptotic signaling pathway [GO:2001234]; positive regulation of aortic smooth muscle cell differentiation [GO:1904831]; positive regulation of canonical NF-kappaB signal transduction [GO:0043123]; protein homotetramerization [GO:0051289]; protein sulfhydration [GO:0044524]; protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine [GO:0018272]; transsulfuration [GO:0019346] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062] | calmodulin binding [GO:0005516]; cystathionine gamma-lyase activity [GO:0004123]; homocysteine desulfhydrase activity [GO:0047982]; identical protein binding [GO:0042802]; L-cysteine desulfhydrase activity [GO:0080146]; L-cystine L-cysteine-lyase (deaminating) [GO:0044540]; pyridoxal phosphate binding [GO:0030170]; selenocystathionine gamma-lyase activity [GO:0098606] | 8501.181927593765 | 0.0291212085417438 | 0.999794992720272 | 1 |
| Q8WYA6 | Q8WYA6 | CTBL1_HUMAN | Beta-catenin-like protein 1 (Nuclear-associated protein) (NAP) (Testis development protein NYD-SP19) | CTNNBL1 | adaptive immune response [GO:0002250]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of apoptotic process [GO:0043065]; somatic diversification of immunoglobulins [GO:0016445] | centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; Prp19 complex [GO:0000974]; spliceosomal complex [GO:0005681] | enzyme binding [GO:0019899] | 4862.603831868695 | -0.177664678901239 | 0.808345000818873 | 1 |
| Q9NRF8 | Q9NRF8 | PYRG2_HUMAN | CTP synthase 2 (EC 6.3.4.2) (CTP synthetase 2) (UTP--ammonia ligase 2) | CTPS2 | 'de novo' CTP biosynthetic process [GO:0044210]; CTP biosynthetic process [GO:0006241]; glutamine metabolic process [GO:0006541]; pyrimidine nucleobase biosynthetic process [GO:0019856]; pyrimidine nucleotide metabolic process [GO:0006220] | cytoophidium [GO:0097268]; cytoplasm [GO:0005737]; cytosol [GO:0005829] | ATP binding [GO:0005524]; CTP synthase activity [GO:0003883]; identical protein binding [GO:0042802] | 6092.8882140787355 | -0.178648191478992 | 0.717868214136483 | 1 |
| P10619 | P10619 | PPGB_HUMAN | Lysosomal protective protein (EC 3.4.16.5) (Carboxypeptidase C) (Carboxypeptidase L) (Cathepsin A) (Protective protein cathepsin A) (PPCA) (Protective protein for beta-galactosidase) [Cleaved into: Lysosomal protective protein 32 kDa chain; Lysosomal protective protein 20 kDa chain] | CTSA | intracellular protein transport [GO:0006886]; negative regulation of chaperone-mediated autophagy [GO:1904715]; proteolysis [GO:0006508]; regulation of chaperone-mediated autophagy [GO:1904714]; regulation of protein stability [GO:0031647] | azurophil granule lumen [GO:0035578]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; membrane [GO:0016020] | carboxypeptidase activity [GO:0004180]; enzyme activator activity [GO:0008047]; serine-type carboxypeptidase activity [GO:0004185] | 61671.4611894432 | 0.184668007312997 | 0.688134491979808 | 1 |
| Q9P2B4 | Q9P2B4 | CT2NL_HUMAN | CTTNBP2 N-terminal-like protein | CTTNBP2NL | negative regulation of transmembrane transport [GO:0034763]; negative regulation of transporter activity [GO:0032410]; protein dephosphorylation [GO:0006470] | actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; lamellipodium [GO:0030027]; stress fiber [GO:0001725] | protein phosphatase 2A binding [GO:0051721] | 14388.3435452588 | -0.146145830330262 | 0.798153098703616 | 1 |
| Q13617 | Q13617 | CUL2_HUMAN | Cullin-2 (CUL-2) | CUL2 | G1/S transition of mitotic cell cycle [GO:0000082]; intrinsic apoptotic signaling pathway [GO:0097193]; protein ubiquitination [GO:0016567]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; ubiquitin-dependent protein catabolic process via the C-end degron rule pathway [GO:0140627] | Cul2-RING ubiquitin ligase complex [GO:0031462]; cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; SCF ubiquitin ligase complex [GO:0019005]; VCB complex [GO:0030891] | protein-containing complex binding [GO:0044877]; protein-macromolecule adaptor activity [GO:0030674]; ubiquitin ligase complex scaffold activity [GO:0160072]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842] | 15654.9256486186 | -0.0571372488304564 | 0.98195087783318 | 1 |
| Q93034 | Q93034 | CUL5_HUMAN | Cullin-5 (CUL-5) (Vasopressin-activated calcium-mobilizing receptor 1) (VACM-1) | CUL5 | ERBB2 signaling pathway [GO:0038128]; G1/S transition of mitotic cell cycle [GO:0000082]; intrinsic apoptotic signaling pathway [GO:0097193]; protein ubiquitination [GO:0016567]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] | Cul5-RING ubiquitin ligase complex [GO:0031466]; cytosol [GO:0005829]; nucleus [GO:0005634]; SCF ubiquitin ligase complex [GO:0019005]; site of DNA damage [GO:0090734] | calcium channel activity [GO:0005262]; protein-macromolecule adaptor activity [GO:0030674]; signaling receptor activity [GO:0038023]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842] | 9644.930303400764 | -0.194296259845384 | 0.826179682118659 | 1 |
| Q13948 | Q13948 | CASP_HUMAN | Protein CASP | CUX1 | intra-Golgi vesicle-mediated transport [GO:0006891] | Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654] | DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977] | 11232.5029311531 | -0.0457962455323153 | 0.999559731512437 | 1 |
| Q9P013 | Q9P013 | CWC15_HUMAN | Spliceosome-associated protein CWC15 homolog | CWC15 | mRNA cis splicing, via spliceosome [GO:0045292]; mRNA splicing, via spliceosome [GO:0000398] | catalytic step 2 spliceosome [GO:0071013]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; Prp19 complex [GO:0000974]; spliceosomal complex [GO:0005681]; U2-type catalytic step 2 spliceosome [GO:0071007] | RNA binding [GO:0003723] | 11597.073845161449 | 0.125551215947161 | 0.837438449481237 | 1 |
| P00387 | P00387 | NB5R3_HUMAN | NADH-cytochrome b5 reductase 3 (B5R) (Cytochrome b5 reductase) (EC 1.6.2.2) (Diaphorase-1) | CYB5R3 | blood circulation [GO:0008015]; cholesterol biosynthetic process [GO:0006695]; nitric oxide biosynthetic process [GO:0006809] | azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; lipid droplet [GO:0005811]; membrane [GO:0016020]; mitochondrial membrane [GO:0031966]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; nitric-oxide synthase complex [GO:1903958] | ADP binding [GO:0043531]; AMP binding [GO:0016208]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; FAD binding [GO:0071949]; NAD binding [GO:0051287] | 183747.460305078 | -0.0759896624959881 | 0.991754597403687 | 1 |
| Q7L576 | Q7L576 | CYFP1_HUMAN | Cytoplasmic FMR1-interacting protein 1 (Specifically Rac1-associated protein 1) (Sra-1) (p140sra-1) | CYFIP1 | axon extension [GO:0048675]; axon guidance [GO:0007411]; cell morphogenesis [GO:0000902]; cellular response to insulin stimulus [GO:0032869]; cognition [GO:0050890]; dendrite extension [GO:0097484]; lamellipodium assembly [GO:0030032]; modification of synaptic structure [GO:0099563]; negative regulation of synaptic vesicle recycling [GO:1903422]; positive regulation of Arp2/3 complex-mediated actin nucleation [GO:2000601]; positive regulation of axon extension [GO:0045773]; positive regulation of dendrite development [GO:1900006]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of neurotrophin TRK receptor signaling pathway [GO:0051388]; positive regulation of ruffle assembly [GO:1900029]; Rac protein signal transduction [GO:0016601]; regulation of actin filament polymerization [GO:0030833]; regulation of cell shape [GO:0008360]; regulation of modification of postsynaptic actin cytoskeleton [GO:1905274]; regulation of myelination [GO:0031641]; regulation of translation [GO:0006417]; regulation of translation at postsynapse, modulating synaptic transmission [GO:0099578]; response to electrical stimulus [GO:0051602]; ruffle organization [GO:0031529] | axonal growth cone [GO:0044295]; central region of growth cone [GO:0090724]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; dendritic spine [GO:0043197]; excitatory synapse [GO:0060076]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; filopodium tip [GO:0032433]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; perinuclear region of cytoplasm [GO:0048471]; peripheral region of growth cone [GO:0090725]; ruffle [GO:0001726]; SCAR complex [GO:0031209]; secretory granule lumen [GO:0034774]; specific granule lumen [GO:0035580]; synapse [GO:0045202]; terminal bouton [GO:0043195]; tertiary granule lumen [GO:1904724] | actin filament binding [GO:0051015]; RNA 7-methylguanosine cap binding [GO:0000340]; small GTPase binding [GO:0031267]; translation repressor activity [GO:0030371] | 17814.10453760025 | -0.177826384278344 | 0.814701870052548 | 1 |
| Q6UW02 | Q6UW02 | CP20A_HUMAN | Cytochrome P450 20A1 (EC 1.14.-.-) | CYP20A1 | membrane [GO:0016020] | heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705] | 17081.8053805018 | 0.0562079223240443 | 0.972322918569626 | 1 | |
| Q7Z449 | Q7Z449 | CP2U1_HUMAN | Cytochrome P450 2U1 (Long-chain fatty acid omega-monooxygenase) (EC 1.14.14.80) | CYP2U1 | cytochrome metabolic process [GO:1903604]; omega-hydroxylase P450 pathway [GO:0097267]; organic acid metabolic process [GO:0006082]; xenobiotic metabolic process [GO:0006805] | cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial inner membrane [GO:0005743] | arachidonic acid omega-hydroxylase activity [GO:0052869]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; long-chain fatty acid omega-hydroxylase activity [GO:0102033]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395] | 3457.8765446692696 | -0.225222573870476 | 0.712863441328217 | 1 |
| O43739 | O43739 | CYH3_HUMAN | Cytohesin-3 (ARF nucleotide-binding site opener 3) (Protein ARNO3) (General receptor of phosphoinositides 1) (Grp1) (PH, SEC7 and coiled-coil domain-containing protein 3) | CYTH3 | establishment of epithelial cell polarity [GO:0090162]; Golgi vesicle transport [GO:0048193]; positive regulation of cell adhesion [GO:0045785]; regulation of ARF protein signal transduction [GO:0032012] | adherens junction [GO:0005912]; bicellular tight junction [GO:0005923]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; ruffle [GO:0001726] | guanyl-nucleotide exchange factor activity [GO:0005085]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547] | 9785.283110514963 | 0.022143807412045 | 0.991640082914805 | 1 |
| Q8NCG7 | Q8NCG7 | DGLB_HUMAN | Diacylglycerol lipase-beta (DAGL-beta) (DGL-beta) (EC 3.1.1.116) (KCCR13L) (PUFA-specific triacylglycerol lipase) (EC 3.1.1.3) (Sn1-specific diacylglycerol lipase beta) | DAGLB | arachidonic acid metabolic process [GO:0019369]; cannabinoid biosynthetic process [GO:1901696]; diacylglycerol catabolic process [GO:0046340]; monoacylglycerol biosynthetic process [GO:0006640]; neuroblast proliferation [GO:0007405]; neurogenesis [GO:0022008]; positive regulation of triglyceride catabolic process [GO:0010898]; prostaglandin biosynthetic process [GO:0001516]; regulation of inflammatory response [GO:0050727] | lysosomal membrane [GO:0005765]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] | acylglycerol lipase activity [GO:0047372]; lipase activity [GO:0016298]; metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806] | 2730.4773367105 | -0.188021964307684 | 0.976434802886356 | 1 |
| O43293 | O43293 | DAPK3_HUMAN | Death-associated protein kinase 3 (DAP kinase 3) (EC 2.7.11.1) (DAP-like kinase) (Dlk) (MYPT1 kinase) (Zipper-interacting protein kinase) (ZIP-kinase) | DAPK3 | apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; cellular response to type II interferon [GO:0071346]; chromatin organization [GO:0006325]; intracellular signal transduction [GO:0035556]; negative regulation of translation [GO:0017148]; positive regulation of apoptotic process [GO:0043065]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell migration [GO:0030335]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of apoptotic process [GO:0042981]; regulation of autophagy [GO:0010506]; regulation of cell motility [GO:2000145]; regulation of cell shape [GO:0008360]; regulation of DNA-templated transcription [GO:0006355]; regulation of focal adhesion assembly [GO:0051893]; regulation of mitotic cell cycle [GO:0007346]; regulation of mitotic nuclear division [GO:0007088]; regulation of myosin II filament organization [GO:0043519]; regulation of smooth muscle contraction [GO:0006940] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605] | ATP binding [GO:0005524]; cAMP response element binding protein binding [GO:0008140]; identical protein binding [GO:0042802]; leucine zipper domain binding [GO:0043522]; protein homodimerization activity [GO:0042803]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; small GTPase binding [GO:0031267] | 12453.41220646795 | -0.00585475514672043 | 0.999996849079915 | 1 |
| P14868 | P14868 | SYDC_HUMAN | Aspartate--tRNA ligase, cytoplasmic (EC 6.1.1.12) (Aspartyl-tRNA synthetase) (AspRS) (Cell proliferation-inducing gene 40 protein) | DARS1 | aspartyl-tRNA aminoacylation [GO:0006422]; protein-containing complex assembly [GO:0065003]; translation [GO:0006412] | aminoacyl-tRNA synthetase multienzyme complex [GO:0017101]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; synapse [GO:0045202] | aminoacylase activity [GO:0004046]; aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; RNA binding [GO:0003723] | 117504.490908734 | 0.0161470560757613 | 0.999999909022204 | 1 |
| Q6PI48 | Q6PI48 | SYDM_HUMAN | Aspartate--tRNA ligase, mitochondrial (EC 6.1.1.12) (Aspartyl-tRNA synthetase) (AspRS) | DARS2 | aspartyl-tRNA aminoacylation [GO:0006422]; mitochondrial asparaginyl-tRNA aminoacylation [GO:0070145]; tRNA aminoacylation [GO:0043039] | mitochondrial matrix [GO:0005759]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654] | aspartate-tRNA ligase activity [GO:0004815]; aspartate-tRNA(Asn) ligase activity [GO:0050560]; ATP binding [GO:0005524]; protein homodimerization activity [GO:0042803]; tRNA binding [GO:0000049] | 8738.732584677644 | 0.373073292532257 | 0.770777812876314 | 1 |
| Q16643 | Q16643 | DREB_HUMAN | Drebrin (Developmentally-regulated brain protein) | DBN1 | actin filament organization [GO:0007015]; cell communication by chemical coupling [GO:0010643]; cell communication by electrical coupling [GO:0010644]; cytoplasmic sequestering of protein [GO:0051220]; in utero embryonic development [GO:0001701]; maintenance of protein location in cell [GO:0032507]; neural precursor cell proliferation [GO:0061351]; neuron projection morphogenesis [GO:0048812]; positive regulation of axon extension [GO:0045773]; positive regulation of dendritic spine morphogenesis [GO:0061003]; positive regulation of receptor localization to synapse [GO:1902685]; positive regulation of synaptic plasticity [GO:0031915]; postsynaptic actin cytoskeleton organization [GO:0098974]; regulation of actin filament polymerization [GO:0030833]; regulation of dendrite development [GO:0050773]; regulation of neuronal synaptic plasticity [GO:0048168] | actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; actomyosin [GO:0042641]; cortical actin cytoskeleton [GO:0030864]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; dendrite [GO:0030425]; gap junction [GO:0005921]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; lamellipodium [GO:0030027]; postsynaptic cytosol [GO:0099524]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211] | actin binding [GO:0003779]; actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; profilin binding [GO:0005522] | 150261.8841709785 | 0.023880012157972 | 0.999978440865755 | 1 |
| Q9UK59 | Q9UK59 | DBR1_HUMAN | Lariat debranching enzyme (EC 3.1.4.-) | DBR1 | mRNA splicing, via spliceosome [GO:0000398]; RNA fragment catabolic process [GO:0000292]; RNA splicing, via transesterification reactions [GO:0000375] | nucleoplasm [GO:0005654]; nucleus [GO:0005634] | metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA lariat debranching enzyme activity [GO:0008419] | 9217.406847372034 | 0.0179629291853869 | 0.990341060559324 | 1 |
| P11182 | P11182 | ODB2_HUMAN | Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial (EC 2.3.1.168) (52 kDa mitochondrial autoantigen of primary biliary cirrhosis) (Branched chain 2-oxo-acid dehydrogenase complex component E2) (BCOADC-E2) (Branched-chain alpha-keto acid dehydrogenase complex component E2) (BCKAD-E2) (BCKADE2) (BCKDH-E2) (Dihydrolipoamide acetyltransferase component of branched-chain alpha-keto acid dehydrogenase complex) (Dihydrolipoamide branched chain transacylase) (Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase) | DBT | branched-chain amino acid catabolic process [GO:0009083] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; microtubule cytoskeleton [GO:0015630]; mitochondrial matrix [GO:0005759]; mitochondrial nucleoid [GO:0042645]; mitochondrial oxoglutarate dehydrogenase complex [GO:0009353]; mitochondrion [GO:0005739] | acetyltransferase activity [GO:0016407]; dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity [GO:0043754]; lipoic acid binding [GO:0031405]; ubiquitin protein ligase binding [GO:0031625] | 6613.63205164856 | -0.105554130204468 | 0.994765655542974 | 1 |
| Q8TEB1 | Q8TEB1 | DCA11_HUMAN | DDB1- and CUL4-associated factor 11 (WD repeat-containing protein 23) | DCAF11 | proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567] | Cul4-RING E3 ubiquitin ligase complex [GO:0080008]; nucleoplasm [GO:0005654] | 1844.1898164602849 | 0.115230296992776 | 0.821256406961991 | 1 | |
| Q9NV06 | Q9NV06 | DCA13_HUMAN | DDB1- and CUL4-associated factor 13 (WD repeat and SOF domain-containing protein 1) | DCAF13 | decidualization [GO:0046697]; epigenetic programming in the zygotic pronuclei [GO:0044725]; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; oocyte growth [GO:0001555]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; rRNA processing [GO:0006364]; spindle assembly involved in female meiosis [GO:0007056] | cell junction [GO:0030054]; centrosome [GO:0005813]; Cul4-RING E3 ubiquitin ligase complex [GO:0080008]; cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; small-subunit processome [GO:0032040] | nuclear estrogen receptor binding [GO:0030331]; RNA binding [GO:0003723]; ubiquitin ligase-substrate adaptor activity [GO:1990756] | 6377.552502624356 | 0.0915574059114376 | 0.878483481366677 | 1 |
| Q58WW2 | Q58WW2 | DCAF6_HUMAN | DDB1- and CUL4-associated factor 6 (Androgen receptor complex-associated protein) (ARCAP) (IQ motif and WD repeat-containing protein 1) (Nuclear receptor interaction protein) (NRIP) | DCAF6 | positive regulation of transcription by RNA polymerase II [GO:0045944]; protein ubiquitination [GO:0016567] | Cul4-RING E3 ubiquitin ligase complex [GO:0080008]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] | nuclear receptor coactivator activity [GO:0030374] | 9618.11717395906 | 0.0903179470965071 | 0.813395751287905 | 1 |
| Q5TAQ9 | Q5TAQ9 | DCAF8_HUMAN | DDB1- and CUL4-associated factor 8 (WD repeat-containing protein 42A) | DCAF8 | protein ubiquitination [GO:0016567] | Cul4-RING E3 ubiquitin ligase complex [GO:0080008]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] | 7455.633064618185 | -0.0797803551246438 | 0.761141960735158 | 1 | |
| Q96C86 | Q96C86 | DCPS_HUMAN | m7GpppX diphosphatase (EC 3.6.1.59) (DCS-1) (Decapping scavenger enzyme) (Hint-related 7meGMP-directed hydrolase) (Histidine triad nucleotide-binding protein 5) (Histidine triad protein member 5) (HINT-5) (Scavenger mRNA-decapping enzyme DcpS) | DCPS | deadenylation-dependent decapping of nuclear-transcribed mRNA [GO:0000290]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; methylguanosine-cap decapping [GO:0110156]; mRNA cis splicing, via spliceosome [GO:0045292]; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:0000288] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932] | 5'-(N(7)-methyl 5'-triphosphoguanosine)-[mRNA] diphosphatase activity [GO:0140932]; identical protein binding [GO:0042802]; RNA 7-methylguanosine cap binding [GO:0000340]; RNA exonuclease activity [GO:0004532] | 10084.259355932649 | 0.0959893832326971 | 0.804320470375518 | 1 |
| P32321 | P32321 | DCTD_HUMAN | Deoxycytidylate deaminase (EC 3.5.4.12) (dCMP deaminase) | DCTD | nucleoside salvage [GO:0043174]; nucleotide biosynthetic process [GO:0009165]; pyrimidine nucleotide metabolic process [GO:0006220] | cytoplasm [GO:0005737]; cytosol [GO:0005829] | dCMP deaminase activity [GO:0004132]; deoxyribonucleoside 5'-monophosphate N-glycosidase activity [GO:0070694]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270] | 27617.3935015313 | 0.174615991265425 | 0.700655355529929 | 1 |
| Q9UJW0 | Q9UJW0 | DCTN4_HUMAN | Dynactin subunit 4 (Dyn4) (Dynactin subunit p62) | DCTN4 | cell cortex [GO:0005938]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytoplasmic dynein complex [GO:0005868]; cytosol [GO:0005829]; dynactin complex [GO:0005869]; focal adhesion [GO:0005925]; kinetochore [GO:0000776]; nucleus [GO:0005634]; sarcomere [GO:0030017]; spindle pole [GO:0000922]; stress fiber [GO:0001725] | 28384.25305474345 | -0.0208220810080686 | 0.999903912396576 | 1 | ||
| Q9BTE1 | Q9BTE1 | DCTN5_HUMAN | Dynactin subunit 5 (Dynactin subunit p25) | DCTN5 | aorta development [GO:0035904]; coronary vasculature development [GO:0060976]; ventricular septum development [GO:0003281] | centrosome [GO:0005813]; cytosol [GO:0005829]; dynactin complex [GO:0005869]; kinetochore [GO:0000776]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654] | 14337.9785005111 | 0.0407861531994851 | 0.917352072637456 | 1 | |
| Q9H773 | Q9H773 | DCTP1_HUMAN | dCTP pyrophosphatase 1 (EC 3.6.1.12) (Deoxycytidine-triphosphatase 1) (dCTPase 1) (RS21C6) (XTP3-transactivated gene A protein) | DCTPP1 | dCTP catabolic process [GO:0006253]; DNA protection [GO:0042262]; nucleoside triphosphate catabolic process [GO:0009143] | cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] | dCTP diphosphatase activity [GO:0047840]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; nucleoside triphosphate diphosphatase activity [GO:0047429]; pyrimidine deoxyribonucleotide binding [GO:0032556] | 9886.765437273214 | -0.0530686355813184 | 0.909477356263614 | 1 |
| Q96GG9 | Q96GG9 | DCNL1_HUMAN | DCN1-like protein 1 (DCNL1) (DCUN1 domain-containing protein 1) (Defective in cullin neddylation protein 1-like protein 1) (Squamous cell carcinoma-related oncogene) | DCUN1D1 | positive regulation of protein neddylation [GO:2000436]; protein neddylation [GO:0045116]; regulation of protein neddylation [GO:2000434]; regulation of protein ubiquitination [GO:0031396] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ubiquitin ligase complex [GO:0000151] | cullin family protein binding [GO:0097602]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin-like protein binding [GO:0032182] | 17405.34907947335 | 0.0344255123214726 | 0.973756330324091 | 1 |
| Q9BTE7 | Q9BTE7 | DCNL5_HUMAN | DCN1-like protein 5 (DCNL5) (DCUN1 domain-containing protein 5) (Defective in cullin neddylation protein 1-like protein 5) (Squamous cell carcinoma-related oncogene 5) | DCUN1D5 | DNA damage response [GO:0006974]; positive regulation of protein neddylation [GO:2000436]; protein neddylation [GO:0045116]; regulation of cell growth [GO:0001558]; regulation of protein neddylation [GO:2000434] | cytoplasm [GO:0005737]; nucleus [GO:0005634]; spindle [GO:0005819]; ubiquitin ligase complex [GO:0000151] | cullin family protein binding [GO:0097602]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin-like protein binding [GO:0032182] | 8614.282238643995 | -0.0678204637450818 | 0.954235542907094 | 1 |
| Q9BW61 | Q9BW61 | DDA1_HUMAN | DET1- and DDB1-associated protein 1 (Placenta cross-immune reaction antigen 1) (PCIA-1) | DDA1 | positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein polyubiquitination [GO:0000209] | Cul4-RING E3 ubiquitin ligase complex [GO:0080008]; nucleoplasm [GO:0005654] | 5005.23543272899 | 0.281518271609984 | 0.679477681174365 | 1 | |
| Q16531 | Q16531 | DDB1_HUMAN | DNA damage-binding protein 1 (DDB p127 subunit) (DNA damage-binding protein a) (DDBa) (Damage-specific DNA-binding protein 1) (HBV X-associated protein 1) (XAP-1) (UV-damaged DNA-binding factor) (UV-damaged DNA-binding protein 1) (UV-DDB 1) (XPE-binding factor) (XPE-BF) (Xeroderma pigmentosum group E-complementing protein) (XPCe) | DDB1 | apoptotic process [GO:0006915]; biological process involved in interaction with symbiont [GO:0051702]; cellular response to UV [GO:0034644]; DNA damage response [GO:0006974]; DNA repair [GO:0006281]; ectopic germ cell programmed cell death [GO:0035234]; epigenetic programming in the zygotic pronuclei [GO:0044725]; negative regulation of apoptotic process [GO:0043066]; negative regulation of developmental process [GO:0051093]; negative regulation of reproductive process [GO:2000242]; nucleotide-excision repair [GO:0006289]; positive regulation by virus of viral protein levels in host cell [GO:0046726]; positive regulation of gluconeogenesis [GO:0045722]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of viral genome replication [GO:0045070]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; regulation of circadian rhythm [GO:0042752]; regulation of mitotic cell cycle phase transition [GO:1901990]; rhythmic process [GO:0048511]; spindle assembly involved in female meiosis [GO:0007056]; ubiquitin-dependent protein catabolic process [GO:0006511]; UV-damage excision repair [GO:0070914]; viral release from host cell [GO:0019076]; Wnt signaling pathway [GO:0016055] | chromosome, telomeric region [GO:0000781]; Cul4-RING E3 ubiquitin ligase complex [GO:0080008]; Cul4A-RING E3 ubiquitin ligase complex [GO:0031464]; Cul4B-RING E3 ubiquitin ligase complex [GO:0031465]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; site of double-strand break [GO:0035861] | cullin family protein binding [GO:0097602]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; protein-containing complex binding [GO:0044877]; protein-macromolecule adaptor activity [GO:0030674]; ubiquitin ligase complex scaffold activity [GO:0160072]; WD40-repeat domain binding [GO:0071987] | 21364.7713367408 | -0.0995979436377803 | 0.999564588290946 | 1 |
| O94830 | O94830 | DDHD2_HUMAN | Phospholipase DDHD2 (EC 3.1.1.-) (DDHD domain-containing protein 2) (KIAA0725p) (SAM, WWE and DDHD domain-containing protein 1) | DDHD2 | lipid droplet organization [GO:0034389]; locomotory behavior [GO:0007626]; mitochondrial fission [GO:0000266]; positive regulation of mitochondrial fission [GO:0090141]; triglyceride catabolic process [GO:0019433]; visual learning [GO:0008542] | centriolar satellite [GO:0034451]; COPII-coated ER to Golgi transport vesicle [GO:0030134]; cytosol [GO:0005829]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; Golgi apparatus [GO:0005794]; membrane [GO:0016020] | metal ion binding [GO:0046872]; phospholipase activity [GO:0004620]; triglyceride lipase activity [GO:0004806] | 5113.344644423079 | -0.0765756239843807 | 0.958252970673671 | 1 |
| Q5TDH0 | Q5TDH0 | DDI2_HUMAN | Protein DDI1 homolog 2 (EC 3.4.23.-) | DDI2 | cellular response to hydroxyurea [GO:0072711]; proteasomal protein catabolic process [GO:0010498]; protein processing [GO:0016485]; regulation of DNA stability [GO:0097752]; regulation of protein stability [GO:0031647] | chromosome [GO:0005694]; cytosol [GO:0005829]; nucleoplasm [GO:0005654] | aspartic-type endopeptidase activity [GO:0004190]; identical protein binding [GO:0042802]; ubiquitin binding [GO:0043130] | 8086.571922023505 | -0.225465622575931 | 0.667773302660093 | 1 |
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