Selected Cell
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stat_data__min_2_Peptides
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| Q8NBI6 | Q8NBI6 | XXLT1_HUMAN | Xyloside xylosyltransferase 1 (EC 2.4.2.62) (UDP-xylose:alpha-xyloside alpha-1,3-xylosyltransferase) | XXYLT1 | O-glycan processing [GO:0016266] | endoplasmic reticulum membrane [GO:0005789] | magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; UDP-xylosyltransferase activity [GO:0035252]; xylosyl alpha-1,3-xylosyltransferase activity [GO:0140560] | 7145.382263151865 | 0.105557570379562 | 0.466839172294299 | 0.823765415826689 |
| Q8IUR7 | Q8IUR7 | ARMC8_HUMAN | Armadillo repeat-containing protein 8 | ARMC8 | proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; GID complex [GO:0034657]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; ubiquitin ligase complex [GO:0000151] | 12571.18589131495 | -0.186716649353425 | 0.467621856254928 | 0.824376302906168 | |
| O95772 | O95772 | STR3N_HUMAN | STARD3 N-terminal-like protein (MLN64 N-terminal domain homolog) | STARD3NL | cholesterol transport [GO:0030301]; vesicle tethering to endoplasmic reticulum [GO:0099044] | cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-endosome membrane contact site [GO:0140284]; endosome [GO:0005768]; intracellular membrane-bounded organelle [GO:0043231]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; organelle membrane contact site [GO:0044232] | cholesterol binding [GO:0015485]; protein homodimerization activity [GO:0042803] | 25718.2422077262 | -0.0857780710212264 | 0.467459810512438 | 0.824376302906168 |
| Q9Y5B9 | Q9Y5B9 | SP16H_HUMAN | FACT complex subunit SPT16 (Chromatin-specific transcription elongation factor 140 kDa subunit) (FACT 140 kDa subunit) (FACTp140) (Facilitates chromatin transcription complex subunit SPT16) (hSPT16) | SUPT16H | DNA repair [GO:0006281]; DNA replication [GO:0006260]; nucleosome assembly [GO:0006334]; nucleosome disassembly [GO:0006337]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; transcription by RNA polymerase II [GO:0006366]; transcription elongation by RNA polymerase II [GO:0006368] | FACT complex [GO:0035101]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] | nucleosome binding [GO:0031491]; RNA binding [GO:0003723] | 17008.0097913216 | -0.175633786292465 | 0.468273724751817 | 0.825012103371827 |
| Q8NHV4 | Q8NHV4 | NEDD1_HUMAN | Protein NEDD1 (Neural precursor cell expressed developmentally down-regulated protein 1) (NEDD-1) | NEDD1 | cell division [GO:0051301]; microtubule nucleation [GO:0007020]; mitotic cell cycle [GO:0000278] | apical part of cell [GO:0045177]; centriole [GO:0005814]; centrosome [GO:0005813]; ciliary basal body [GO:0036064]; cytosol [GO:0005829]; fibrillar center [GO:0001650]; nucleoplasm [GO:0005654]; pericentriolar material [GO:0000242]; spindle pole [GO:0000922] | gamma-tubulin binding [GO:0043015] | 6599.400247817661 | -0.226851865298692 | 0.468650012118218 | 0.82519373531404 |
| P22061 | P22061 | PIMT_HUMAN | Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PIMT) (EC 2.1.1.77) (L-isoaspartyl protein carboxyl methyltransferase) (Protein L-isoaspartyl/D-aspartyl methyltransferase) (Protein-beta-aspartate methyltransferase) | PCMT1 | protein methylation [GO:0006479]; protein repair [GO:0030091] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular vesicle [GO:1903561] | cadherin binding [GO:0045296]; protein-L-isoaspartate (D-aspartate) O-methyltransferase activity [GO:0004719] | 96965.10604260315 | -0.194289616473888 | 0.46932011322658 | 0.825743361447327 |
| Q15173 | Q15173 | 2A5B_HUMAN | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform (PP2A B subunit isoform B'-beta) (PP2A B subunit isoform B56-beta) (PP2A B subunit isoform PR61-beta) (PP2A B subunit isoform R5-beta) | PPP2R5B | cellular response to growth factor stimulus [GO:0071363]; negative regulation of G0 to G1 transition [GO:0070317]; positive regulation of neuron projection development [GO:0010976]; positive regulation of neurotrophin TRK receptor signaling pathway [GO:0051388]; positive regulation of protein-containing complex assembly [GO:0031334]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of protein autophosphorylation [GO:0031952]; signal transduction [GO:0007165] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; protein phosphatase type 2A complex [GO:0000159] | protein phosphatase activator activity [GO:0072542]; protein phosphatase regulator activity [GO:0019888] | 5544.69725330895 | 0.132909481128463 | 0.469207169434656 | 0.825743361447327 |
| P27694 | P27694 | RFA1_HUMAN | Replication protein A 70 kDa DNA-binding subunit (RP-A p70) (Replication factor A protein 1) (RF-A protein 1) (Single-stranded DNA-binding protein) [Cleaved into: Replication protein A 70 kDa DNA-binding subunit, N-terminally processed] | RPA1 | base-excision repair [GO:0006284]; DNA damage response [GO:0006974]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA-templated DNA replication [GO:0006261]; double-strand break repair via homologous recombination [GO:0000724]; meiotic cell cycle [GO:0051321]; mismatch repair [GO:0006298]; nucleotide-excision repair [GO:0006289]; protein localization to chromosome [GO:0034502]; protein localization to site of double-strand break [GO:1990166]; telomere maintenance [GO:0000723]; telomere maintenance via telomerase [GO:0007004] | chromosome, telomeric region [GO:0000781]; DNA replication factor A complex [GO:0005662]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; site of DNA damage [GO:0090734]; site of double-strand break [GO:0035861] | chromatin-protein adaptor activity [GO:0140463]; damaged DNA binding [GO:0003684]; G-rich strand telomeric DNA binding [GO:0098505]; metal ion binding [GO:0046872]; single-stranded DNA binding [GO:0003697]; single-stranded telomeric DNA binding [GO:0043047] | 7469.3544467251595 | -0.198870632782892 | 0.469417466858778 | 0.825743361447327 |
| Q92536 | Q92536 | YLAT2_HUMAN | Y+L amino acid transporter 2 (Cationic amino acid transporter, y+ system) (Solute carrier family 7 member 6) (y(+)L-type amino acid transporter 2) (Y+LAT2) (y+LAT-2) | SLC7A6 | amino acid transmembrane transport [GO:0003333]; glycine betaine transport [GO:0031460]; L-arginine transmembrane transport [GO:1903826]; leucine transport [GO:0015820]; neutral amino acid transport [GO:0015804]; nitric oxide biosynthetic process [GO:0006809]; ornithine transport [GO:0015822] | plasma membrane [GO:0005886] | amino acid transmembrane transporter activity [GO:0015171]; arginine binding [GO:0034618]; basic amino acid transmembrane transporter activity [GO:0015174]; L-amino acid transmembrane transporter activity [GO:0015179]; L-arginine transmembrane transporter activity [GO:0061459]; L-lysine:L-arginine antiporter activity [GO:0106439] | 2920.2283504101197 | -0.14348760994666 | 0.469886337417345 | 0.826311603912686 |
| Q9Y2G8 | Q9Y2G8 | DJC16_HUMAN | DnaJ homolog subfamily C member 16 (Endoplasmic reticulum DNA J domain-containing protein 8) (ER-resident protein ERdj8) (ERdj8) | DNAJC16 | regulation of autophagosome size [GO:0016243] | endoplasmic reticulum membrane [GO:0005789] | 3396.41886846358 | 0.217672522452551 | 0.470390618755761 | 0.826890263274388 | |
| P22392 | P22392 | NDKB_HUMAN | Nucleoside diphosphate kinase B (NDK B) (NDP kinase B) (EC 2.7.4.6) (C-myc purine-binding transcription factor PUF) (Histidine protein kinase NDKB) (EC 2.7.13.3) (nm23-H2) | NME2 | cell adhesion [GO:0007155]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; integrin-mediated signaling pathway [GO:0007229]; negative regulation of apoptotic process [GO:0043066]; nucleoside triphosphate biosynthetic process [GO:0009142]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of apoptotic process [GO:0042981]; regulation of epidermis development [GO:0045682]; UTP biosynthetic process [GO:0006228] | cell periphery [GO:0071944]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lamellipodium [GO:0030027]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; secretory granule lumen [GO:0034774] | ATP binding [GO:0005524]; DNA binding [GO:0003677]; G-quadruplex DNA binding [GO:0051880]; GDP binding [GO:0019003]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; protein histidine kinase activity [GO:0004673]; transcription coactivator activity [GO:0003713] | 309428.2846950395 | -0.116404486391241 | 0.470653211976686 | 0.826890263274388 |
| Q5VU43 | Q5VU43 | MYOME_HUMAN | Myomegalin (Cardiomyopathy-associated protein 2) (Phosphodiesterase 4D-interacting protein) | PDE4DIP | astral microtubule organization [GO:0030953]; centrosome cycle [GO:0007098]; positive regulation of microtubule nucleation [GO:0090063]; protein-containing complex assembly [GO:0065003]; regulation of Golgi organization [GO:1903358] | centrosome [GO:0005813]; cytoplasm [GO:0005737]; Golgi apparatus [GO:0005794]; myofibril [GO:0030016]; nucleus [GO:0005634] | enzyme binding [GO:0019899]; molecular adaptor activity [GO:0060090] | 9357.80629005162 | -0.148702809699054 | 0.471220353295437 | 0.827548026384439 |
| Q9P2C4 | Q9P2C4 | TM181_HUMAN | Transmembrane protein 181 | TMEM181 | membrane [GO:0016020] | toxic substance binding [GO:0015643] | 12898.42718042895 | 0.0772140249300948 | 0.471846404496187 | 0.828109667805262 | |
| Q5VYS8 | Q5VYS8 | TUT7_HUMAN | Terminal uridylyltransferase 7 (TUTase 7) (EC 2.7.7.52) (Zinc finger CCHC domain-containing protein 6) | TUT7 | miRNA metabolic process [GO:0010586]; oocyte maturation [GO:0001556]; polyuridylation-dependent mRNA catabolic process [GO:1990074]; pre-miRNA processing [GO:0031054]; retrotransposon silencing by mRNA destabilization [GO:0141008]; RNA 3' uridylation [GO:0071076]; RNA 3'-end processing [GO:0031123] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654] | miRNA binding [GO:0035198]; RNA binding [GO:0003723]; RNA uridylyltransferase activity [GO:0050265]; uridylyltransferase activity [GO:0070569]; zinc ion binding [GO:0008270] | 5414.349439816725 | 0.453306489099549 | 0.471931895048216 | 0.828109667805262 |
| Q9Y2U8 | Q9Y2U8 | MAN1_HUMAN | Inner nuclear membrane protein Man1 (LEM domain-containing protein 3) | LEMD3 | negative regulation of activin receptor signaling pathway [GO:0032926]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nuclear envelope organization [GO:0006998] | membrane [GO:0016020]; nuclear inner membrane [GO:0005637]; nuclear membrane [GO:0031965] | chromatin DNA binding [GO:0031490]; U1 snRNP binding [GO:1990446] | 7345.332028498015 | 0.0695922959133257 | 0.472146723548497 | 0.828230134868664 |
| Q96T51 | Q96T51 | RUFY1_HUMAN | RUN and FYVE domain-containing protein 1 (FYVE-finger protein EIP1) (La-binding protein 1) (Rab4-interacting protein) (Zinc finger FYVE domain-containing protein 12) | RUFY1 | endocytosis [GO:0006897]; protein transport [GO:0015031]; regulation of endocytosis [GO:0030100]; small GTPase-mediated signal transduction [GO:0007264] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome membrane [GO:0031901]; endosome [GO:0005768]; intracellular membrane-bounded organelle [GO:0043231]; nuclear speck [GO:0016607] | identical protein binding [GO:0042802]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]; SH2 domain binding [GO:0042169]; SH3 domain binding [GO:0017124] | 9387.939519302014 | -0.140424435472075 | 0.473911916068364 | 0.830812164741135 |
| Q9NQS1 | Q9NQS1 | AVEN_HUMAN | Cell death regulator Aven | AVEN | apoptotic process [GO:0006915]; negative regulation of apoptotic process [GO:0043066]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972] | cytosol [GO:0005829]; endomembrane system [GO:0012505]; membrane [GO:0016020] | 15425.9079411568 | -0.134422835223242 | 0.474666398901842 | 0.830993049167064 | |
| Q14344 | Q14344 | GNA13_HUMAN | Guanine nucleotide-binding protein subunit alpha-13 (G alpha-13) (G-protein subunit alpha-13) | GNA13 | adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; branching involved in blood vessel morphogenesis [GO:0001569]; cell differentiation [GO:0030154]; in utero embryonic development [GO:0001701]; negative regulation of vascular associated smooth muscle cell migration [GO:1904753]; negative regulation of vascular associated smooth muscle cell proliferation [GO:1904706]; platelet activation [GO:0030168]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; regulation of blood pressure [GO:0008217]; regulation of cell shape [GO:0008360]; regulation of fibroblast migration [GO:0010762]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; signal transduction [GO:0007165] | brush border membrane [GO:0031526]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; heterotrimeric G-protein complex [GO:0005834]; melanosome [GO:0042470]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886] | D5 dopamine receptor binding [GO:0031752]; G-protein beta/gamma-subunit complex binding [GO:0031683]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; guanyl-nucleotide exchange factor activity [GO:0005085]; metal ion binding [GO:0046872] | 15173.24503649785 | -0.120002048377719 | 0.476068379385155 | 0.830993049167064 |
| Q9UBN7 | Q9UBN7 | HDAC6_HUMAN | Histone deacetylase 6 (HD6) (EC 3.5.1.98) (Protein deacetylase HDAC6) (EC 3.5.1.-) (Tubulin-lysine deacetylase HDAC6) (EC 3.5.1.-) | HDAC6 | actin filament organization [GO:0007015]; aggresome assembly [GO:0070842]; autophagy [GO:0006914]; axonal transport of mitochondrion [GO:0019896]; cellular response to heat [GO:0034605]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to misfolded protein [GO:0071218]; cellular response to parathyroid hormone stimulus [GO:0071374]; cellular response to topologically incorrect protein [GO:0035967]; cilium assembly [GO:0060271]; cilium disassembly [GO:0061523]; collateral sprouting [GO:0048668]; dendritic spine morphogenesis [GO:0060997]; erythrocyte enucleation [GO:0043131]; intracellular protein transport [GO:0006886]; lysosome localization [GO:0032418]; negative regulation of aggrephagy [GO:1905336]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; negative regulation of microtubule depolymerization [GO:0007026]; negative regulation of oxidoreductase activity [GO:0051354]; negative regulation of protein acetylation [GO:1901984]; negative regulation of protein-containing complex assembly [GO:0031333]; negative regulation of protein-containing complex disassembly [GO:0043242]; negative regulation of proteolysis [GO:0045861]; negative regulation of transcription by RNA polymerase II [GO:0000122]; parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization [GO:0061734]; peptidyl-lysine deacetylation [GO:0034983]; polyubiquitinated misfolded protein transport [GO:0070845]; positive regulation of cellular response to oxidative stress [GO:1900409]; positive regulation of cholangiocyte proliferation [GO:1904056]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of signaling receptor activity [GO:2000273]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of tubulin deacetylation [GO:0090044]; protein deacetylation [GO:0006476]; protein destabilization [GO:0031648]; protein polyubiquitination [GO:0000209]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; protein-containing complex disassembly [GO:0032984]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of autophagy [GO:0010506]; regulation of autophagy of mitochondrion [GO:1903146]; regulation of establishment of protein localization [GO:0070201]; regulation of fat cell differentiation [GO:0045598]; regulation of macroautophagy [GO:0016241]; regulation of microtubule-based movement [GO:0060632]; regulation of protein stability [GO:0031647]; response to amphetamine [GO:0001975]; response to corticosterone [GO:0051412]; response to dexamethasone [GO:0071548]; response to growth factor [GO:0070848]; response to immobilization stress [GO:0035902]; response to misfolded protein [GO:0051788]; tubulin deacetylation [GO:0090042]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162] | aggresome [GO:0016235]; axon [GO:0030424]; axon cytoplasm [GO:1904115]; caveola [GO:0005901]; cell leading edge [GO:0031252]; centrosome [GO:0005813]; ciliary basal body [GO:0036064]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; histone deacetylase complex [GO:0000118]; inclusion body [GO:0016234]; microtubule [GO:0005874]; microtubule associated complex [GO:0005875]; multivesicular body [GO:0005771]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471] | actin binding [GO:0003779]; alpha-tubulin binding [GO:0043014]; beta-catenin binding [GO:0008013]; beta-tubulin binding [GO:0048487]; dynein complex binding [GO:0070840]; enzyme binding [GO:0019899]; histone deacetylase activity [GO:0004407]; histone deacetylase binding [GO:0042826]; Hsp90 protein binding [GO:0051879]; microtubule binding [GO:0008017]; misfolded protein binding [GO:0051787]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein lysine deacetylase activity [GO:0033558]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; tau protein binding [GO:0048156]; transcription corepressor binding [GO:0001222]; tubulin deacetylase activity [GO:0042903]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270] | 8452.073901488711 | 0.344428202108758 | 0.476052860599025 | 0.830993049167064 |
| Q3ZCW2 | Q3ZCW2 | LEGL_HUMAN | Galectin-related protein (Galectin-like protein) (Lectin galactoside-binding-like protein) | LGALSL | carbohydrate binding [GO:0030246] | 2177.36463553237 | -1.98971341833977 | 0.475168161308972 | 0.830993049167064 | ||
| Q9BYT8 | Q9BYT8 | NEUL_HUMAN | Neurolysin, mitochondrial (EC 3.4.24.16) (Angiotensin-binding protein) (Microsomal endopeptidase) (MEP) (Mitochondrial oligopeptidase M) (Neurotensin endopeptidase) | NLN | G protein-coupled receptor signaling pathway [GO:0007186]; peptide metabolic process [GO:0006518]; proteolysis [GO:0006508]; regulation of gluconeogenesis [GO:0006111]; regulation of skeletal muscle fiber differentiation [GO:1902809] | cytosol [GO:0005829]; extracellular region [GO:0005576]; mitochondrial intermembrane space [GO:0005758]; plasma membrane [GO:0005886] | metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; peptide binding [GO:0042277] | 10422.04905856485 | -0.118722711541667 | 0.475765609856385 | 0.830993049167064 |
| Q6PK18 | Q6PK18 | OGFD3_HUMAN | 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 3 (EC 1.14.11.-) | OGFOD3 | membrane [GO:0016020] | dioxygenase activity [GO:0051213]; iron ion binding [GO:0005506]; L-ascorbic acid binding [GO:0031418]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705] | 20136.514165851302 | 0.160322788506684 | 0.47440399407851 | 0.830993049167064 | |
| P19021 | P19021 | AMD_HUMAN | Peptidyl-glycine alpha-amidating monooxygenase (PAM) [Includes: Peptidylglycine alpha-hydroxylating monooxygenase (PHM) (EC 1.14.17.3); Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (EC 4.3.2.5) (Peptidylamidoglycolate lyase) (PAL)] | PAM | fatty acid primary amide biosynthetic process [GO:0062112]; peptide amidation [GO:0001519]; response to zinc ion [GO:0010043] | extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; secretory granule membrane [GO:0030667]; transport vesicle membrane [GO:0030658] | calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; L-ascorbic acid binding [GO:0031418]; peptidylamidoglycolate lyase activity [GO:0004598]; peptidylglycine monooxygenase activity [GO:0004504]; zinc ion binding [GO:0008270] | 9794.023491299495 | 0.225430273647057 | 0.475056906256061 | 0.830993049167064 |
| Q8IY17 | Q8IY17 | PLPL6_HUMAN | Patatin-like phospholipase domain-containing protein 6 (EC 3.1.1.5) (Neuropathy target esterase) | PNPLA6 | glycerophospholipid catabolic process [GO:0046475]; phosphatidylcholine metabolic process [GO:0046470] | cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020] | lysophospholipase activity [GO:0004622]; phosphatidyl phospholipase B activity [GO:0102545] | 9710.888284660845 | -0.169432791548949 | 0.47432377803614 | 0.830993049167064 |
| Q00765 | Q00765 | REEP5_HUMAN | Receptor expression-enhancing protein 5 (Polyposis locus protein 1) (Protein TB2) | REEP5 | endoplasmic reticulum membrane organization [GO:0090158]; endoplasmic reticulum organization [GO:0007029]; regulation of intracellular transport [GO:0032386] | endoplasmic reticulum [GO:0005783]; endoplasmic reticulum tubular network [GO:0071782]; sarcoplasmic reticulum membrane [GO:0033017] | 65321.973666089005 | 0.165479490640658 | 0.475849311817888 | 0.830993049167064 | |
| Q6PML9 | Q6PML9 | ZNT9_HUMAN | Proton-coupled zinc antiporter SLC30A9, mitochondrial (Human embryonic lung protein) (HuEL) (Solute carrier family 30 member 9) (Zinc transporter 9) (ZnT-9) | SLC30A9 | intracellular zinc ion homeostasis [GO:0006882]; nucleotide-excision repair [GO:0006289]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of mitochondrion organization [GO:0010821]; zinc ion transport [GO:0006829] | cytoplasmic vesicle [GO:0031410]; cytoskeleton [GO:0005856]; endoplasmic reticulum [GO:0005783]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634] | antiporter activity [GO:0015297]; chromatin binding [GO:0003682]; nuclear receptor binding [GO:0016922]; nuclear receptor coactivator activity [GO:0030374]; zinc ion transmembrane transporter activity [GO:0005385] | 12097.716588432599 | -0.143133230645323 | 0.475376850135048 | 0.830993049167064 |
| Q5W111 | Q5W111 | SPRY7_HUMAN | SPRY domain-containing protein 7 (Chronic lymphocytic leukemia deletion region gene 6 protein) (CLL deletion region gene 6 protein) | SPRYD7 | 17419.77066050985 | -0.194306678886756 | 0.474830598051917 | 0.830993049167064 | |||
| O43657 | O43657 | TSN6_HUMAN | Tetraspanin-6 (Tspan-6) (A15 homolog) (Putative NF-kappa-B-activating protein 321) (T245 protein) (Tetraspanin TM4-D) (Transmembrane 4 superfamily member 6) | TSPAN6 | negative regulation of canonical NF-kappaB signal transduction [GO:0043124]; negative regulation of cytoplasmic pattern recognition receptor signaling pathway [GO:0039532]; positive regulation of canonical NF-kappaB signal transduction [GO:0043123] | extracellular exosome [GO:0070062]; membrane [GO:0016020] | 22639.567811035347 | -0.133863597167303 | 0.475394176721599 | 0.830993049167064 | |
| Q8TEQ6 | Q8TEQ6 | GEMI5_HUMAN | Gem-associated protein 5 (Gemin5) | GEMIN5 | mRNA splicing, via spliceosome [GO:0000398]; protein-containing complex assembly [GO:0065003]; regulation of translation [GO:0006417]; spliceosomal snRNP assembly [GO:0000387]; translation [GO:0006412] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; Gemini of coiled bodies [GO:0097504]; membrane [GO:0016020]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; SMN complex [GO:0032797]; SMN-Gemin2 complex [GO:0034718]; SMN-Sm protein complex [GO:0034719] | mRNA 3'-UTR binding [GO:0003730]; ribosome binding [GO:0043022]; RNA 7-methylguanosine cap binding [GO:0000340]; RNA binding [GO:0003723]; snRNA binding [GO:0017069]; U1 snRNA binding [GO:0030619]; U4 snRNA binding [GO:0030621]; U4atac snRNA binding [GO:0030622] | 5012.902982754675 | -0.20743553751673 | 0.476447962625834 | 0.831399493759771 |
| Q5T0D9 | Q5T0D9 | TPRGL_HUMAN | Tumor protein p63-regulated gene 1-like protein (Mossy fiber terminal-associated vertebrate-specific presynaptic protein) (Protein FAM79A) | TPRG1L | calmodulin dependent kinase signaling pathway [GO:0099004]; negative regulation of synaptic transmission [GO:0050805]; regulation of synaptic transmission, glutamatergic [GO:0051966]; synaptic vesicle docking [GO:0016081] | calyx of Held [GO:0044305]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; presynaptic active zone [GO:0048786]; synaptic vesicle [GO:0008021]; synaptic vesicle membrane [GO:0030672] | calmodulin binding [GO:0005516]; identical protein binding [GO:0042802] | 12124.7732073115 | -0.157279339774679 | 0.476963614217288 | 0.832043053619197 |
| Q9Y3Y2 | Q9Y3Y2 | CHTOP_HUMAN | Chromatin target of PRMT1 protein (Friend of PRMT1 protein) (Small arginine- and glycine-rich protein) (SRAG) | CHTOP | chromatin remodeling [GO:0006338]; mRNA export from nucleus [GO:0006406]; positive regulation of ATP-dependent activity [GO:0032781]; positive regulation of helicase activity [GO:0051096] | nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription export complex [GO:0000346] | methyl-CpG binding [GO:0008327]; mRNA binding [GO:0003729]; RNA binding [GO:0003723] | 25334.80675505575 | -0.112518565191778 | 0.477688514246331 | 0.832926670029143 |
| O15270 | O15270 | SPTC2_HUMAN | Serine palmitoyltransferase 2 (EC 2.3.1.50) (Long chain base biosynthesis protein 2) (LCB 2) (Long chain base biosynthesis protein 2a) (LCB2a) (Serine-palmitoyl-CoA transferase 2) (SPT 2) | SPTLC2 | adipose tissue development [GO:0060612]; ceramide biosynthetic process [GO:0046513]; positive regulation of lipophagy [GO:1904504]; sphinganine biosynthetic process [GO:0046511]; sphingolipid biosynthetic process [GO:0030148]; sphingomyelin biosynthetic process [GO:0006686]; sphingosine biosynthetic process [GO:0046512] | endoplasmic reticulum membrane [GO:0005789]; serine C-palmitoyltransferase complex [GO:0017059] | pyridoxal phosphate binding [GO:0030170]; serine C-palmitoyltransferase activity [GO:0004758] | 9474.194095682495 | 0.359843200545569 | 0.477764150652085 | 0.832926670029143 |
| Q96A73 | Q96A73 | P33MX_HUMAN | Putative monooxygenase p33MONOX (EC 1.-.-.-) (Brain-derived rescue factor p60MONOX) (Flavin monooxygenase motif-containing protein of 33 kDa) | KIAA1191 | cytoplasm [GO:0005737] | oxidoreductase activity [GO:0016491] | 11376.5226178436 | 0.203714770407532 | 0.478165842396776 | 0.833370551528802 | |
| Q15717 | Q15717 | ELAV1_HUMAN | ELAV-like protein 1 (Hu-antigen R) (HuR) | ELAVL1 | 3'-UTR-mediated mRNA stabilization [GO:0070935]; mRNA destabilization [GO:0061157]; mRNA stabilization [GO:0048255]; negative regulation of miRNA-mediated gene silencing [GO:0060965]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of translation [GO:0045727]; post-transcriptional gene silencing [GO:0016441]; protein homooligomerization [GO:0051260]; protein import into nucleus [GO:0006606]; regulation of stem cell population maintenance [GO:2000036] | cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]; postsynapse [GO:0098794]; ribonucleoprotein complex [GO:1990904]; sarcoplasm [GO:0016528] | double-stranded RNA binding [GO:0003725]; lncRNA binding [GO:0106222]; miRNA binding [GO:0035198]; mRNA 3'-UTR AU-rich region binding [GO:0035925]; mRNA 3'-UTR binding [GO:0003730]; mRNA binding [GO:0003729]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; RNA binding [GO:0003723] | 77213.41851180821 | 0.128677040071444 | 0.478729073993154 | 0.834095612929032 |
| Q562R1 | Q562R1 | ACTBL_HUMAN | Beta-actin-like protein 2 (Kappa-actin) | ACTBL2 | axonogenesis [GO:0007409]; cell motility [GO:0048870] | actin filament [GO:0005884]; axon [GO:0030424]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; NuA4 histone acetyltransferase complex [GO:0035267] | ATP binding [GO:0005524]; protein kinase binding [GO:0019901]; structural constituent of postsynaptic actin cytoskeleton [GO:0098973] | 675852.5861100231 | -0.312162759069907 | 0.479885329834319 | 0.835453863498024 |
| Q13043 | Q13043 | STK4_HUMAN | Serine/threonine-protein kinase 4 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 1) (MST-1) (STE20-like kinase MST1) (Serine/threonine-protein kinase Krs-2) [Cleaved into: Serine/threonine-protein kinase 4 37kDa subunit (MST1/N); Serine/threonine-protein kinase 4 18kDa subunit (MST1/C)] | STK4 | apoptotic process [GO:0006915]; branching involved in blood vessel morphogenesis [GO:0001569]; canonical Wnt signaling pathway [GO:0060070]; cell differentiation involved in embryonic placenta development [GO:0060706]; cell morphogenesis [GO:0000902]; central nervous system development [GO:0007417]; endocardium development [GO:0003157]; epithelial cell proliferation [GO:0050673]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; hepatocyte apoptotic process [GO:0097284]; hippo signaling [GO:0035329]; intracellular signal transduction [GO:0035556]; keratinocyte differentiation [GO:0030216]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of organ growth [GO:0046621]; neural tube formation [GO:0001841]; organ growth [GO:0035265]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of apoptotic process [GO:0043065]; positive regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902043]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of hepatocyte apoptotic process [GO:1903945]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein binding [GO:0032092]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of substrate-dependent cell migration, cell attachment to substrate [GO:1904237]; primitive hemopoiesis [GO:0060215]; protein autophosphorylation [GO:0046777]; protein import into nucleus [GO:0006606]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; regulation of cell differentiation involved in embryonic placenta development [GO:0060800]; regulation of MAPK cascade [GO:0043408]; signal transduction [GO:0007165] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991] | ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activator activity [GO:0043539]; protein serine/threonine kinase activity [GO:0004674]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629] | 7493.05293862851 | 0.294841259546267 | 0.47995099288494 | 0.835453863498024 |
| P49354 | P49354 | FNTA_HUMAN | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (EC 2.5.1.58) (EC 2.5.1.59) (CAAX farnesyltransferase subunit alpha) (FTase-alpha) (Ras proteins prenyltransferase subunit alpha) (Type I protein geranyl-geranyltransferase subunit alpha) (GGTase-I-alpha) | FNTA | positive regulation of deacetylase activity [GO:0090045]; positive regulation of Rac protein signal transduction [GO:0035022]; positive regulation of skeletal muscle acetylcholine-gated channel clustering [GO:1904395]; positive regulation of tubulin deacetylation [GO:0090044]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; transforming growth factor beta receptor signaling pathway [GO:0007179] | CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; microtubule associated complex [GO:0005875]; plasma membrane [GO:0005886]; protein farnesyltransferase complex [GO:0005965] | alpha-tubulin binding [GO:0043014]; CAAX-protein geranylgeranyltransferase activity [GO:0004662]; microtubule binding [GO:0008017]; molecular adaptor activity [GO:0060090]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]; Rab geranylgeranyltransferase activity [GO:0004663]; receptor tyrosine kinase binding [GO:0030971] | 14564.154889268299 | 0.151383004176526 | 0.480231937696453 | 0.835686166765387 |
| Q8IWW6 | Q8IWW6 | RHG12_HUMAN | Rho GTPase-activating protein 12 (Rho-type GTPase-activating protein 12) | ARHGAP12 | actin filament organization [GO:0007015]; morphogenesis of an epithelial sheet [GO:0002011]; negative regulation of small GTPase mediated signal transduction [GO:0051058]; phagocytosis, engulfment [GO:0006911]; signal transduction [GO:0007165] | cytoplasm [GO:0005737]; phagocytic cup [GO:0001891] | GTPase activator activity [GO:0005096] | 7570.91189266654 | 0.166417074067799 | 0.482635799473991 | 0.839308653664799 |
| Q8NC56 | Q8NC56 | LEMD2_HUMAN | LEM domain-containing protein 2 (hLEM2) | LEMD2 | heart formation [GO:0060914]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction [GO:0051898]; neurogenesis [GO:0022008]; nuclear envelope organization [GO:0006998]; nuclear membrane organization [GO:0071763]; protein localization to chromatin [GO:0071168]; skeletal muscle cell differentiation [GO:0035914] | chromatin [GO:0000785]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nuclear envelope [GO:0005635]; nuclear inner membrane [GO:0005637]; nuclear membrane [GO:0031965]; nuclear periphery [GO:0034399]; spindle [GO:0005819] | chromatin DNA binding [GO:0031490] | 20021.1357968149 | 0.143746577101568 | 0.482758013112174 | 0.839308653664799 |
| P09497 | P09497 | CLCB_HUMAN | Clathrin light chain B (Lcb) | CLTB | clathrin-dependent endocytosis [GO:0072583]; intracellular protein transport [GO:0006886] | ciliary membrane [GO:0060170]; clathrin coat [GO:0030118]; clathrin coat of coated pit [GO:0030132]; clathrin coat of trans-Golgi network vesicle [GO:0030130]; clathrin vesicle coat [GO:0030125]; clathrin-coated endocytic vesicle [GO:0045334]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]; postsynaptic endocytic zone cytoplasmic component [GO:0099631]; presynaptic endocytic zone membrane [GO:0098835]; synaptic vesicle membrane [GO:0030672]; trans-Golgi network [GO:0005802] | clathrin heavy chain binding [GO:0032050]; peptide binding [GO:0042277]; structural molecule activity [GO:0005198] | 88138.54686049916 | 0.165691541105492 | 0.483239492280196 | 0.83944925622063 |
| P82914 | P82914 | RT15_HUMAN | Small ribosomal subunit protein uS15m (28S ribosomal protein S15, mitochondrial) (MRP-S15) (S15mt) | MRPS15 | mitochondrial translation [GO:0032543]; translation [GO:0006412] | mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial small ribosomal subunit [GO:0005763]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654] | RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735] | 27500.667374520097 | -0.316583859548132 | 0.483283352239974 | 0.83944925622063 |
| P46781 | P46781 | RS9_HUMAN | Small ribosomal subunit protein uS4 (40S ribosomal protein S9) | RPS9 | cytoplasmic translation [GO:0002181]; positive regulation of cell population proliferation [GO:0008284]; ribosomal small subunit biogenesis [GO:0042274]; translation [GO:0006412] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic ribosome [GO:0022626]; cytosolic small ribosomal subunit [GO:0022627]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; ribosome [GO:0005840]; small-subunit processome [GO:0032040]; synapse [GO:0045202] | RNA binding [GO:0003723]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation regulator activity [GO:0045182] | 398170.8189111785 | 0.163433860667196 | 0.483255969813456 | 0.83944925622063 |
| Q06033 | Q06033 | ITIH3_HUMAN | Inter-alpha-trypsin inhibitor heavy chain H3 (ITI heavy chain H3) (ITI-HC3) (Inter-alpha-inhibitor heavy chain 3) (Serum-derived hyaluronan-associated protein) (SHAP) | ITIH3 | hyaluronan metabolic process [GO:0030212] | extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; platelet dense granule lumen [GO:0031089] | endopeptidase inhibitor activity [GO:0004866]; serine-type endopeptidase inhibitor activity [GO:0004867] | 14379.8295965152 | -0.200430524433945 | 0.484771821700041 | 0.841609504059185 |
| Q9Y4W2 | Q9Y4W2 | LAS1L_HUMAN | Ribosomal biogenesis protein LAS1L (Endoribonuclease LAS1L) (EC 3.1.-.-) (Protein LAS1 homolog) | LAS1L | maturation of 5.8S rRNA [GO:0000460]; maturation of LSU-rRNA [GO:0000470]; rRNA processing [GO:0006364] | Las1 complex [GO:0090730]; membrane [GO:0016020]; MLL1 complex [GO:0071339]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; preribosome, large subunit precursor [GO:0030687] | endonuclease activity [GO:0004519]; RNA binding [GO:0003723] | 8075.657242223844 | -0.17937496361991 | 0.484910659279039 | 0.841609504059185 |
| P61254 | P61254 | RL26_HUMAN | Large ribosomal subunit protein uL24 (60S ribosomal protein L26) | RPL26 | cellular response to gamma radiation [GO:0071480]; cellular response to UV [GO:0034644]; cytoplasmic translation [GO:0002181]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:1902164]; positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902167]; positive regulation of translation [GO:0045727]; regulation of translation involved in cellular response to UV [GO:1904803]; ribosomal large subunit biogenesis [GO:0042273]; rRNA processing [GO:0006364]; translation [GO:0006412] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; cytosolic ribosome [GO:0022626]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; ribonucleoprotein complex [GO:1990904]; synapse [GO:0045202] | mRNA 5'-UTR binding [GO:0048027]; RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735] | 201878.32915597002 | 0.245419599356562 | 0.484972649268132 | 0.841609504059185 |
| Q92804 | Q92804 | RBP56_HUMAN | TATA-binding protein-associated factor 2N (68 kDa TATA-binding protein-associated factor) (TAF(II)68) (TAFII68) (RNA-binding protein 56) | TAF15 | mRNA stabilization [GO:0048255]; positive regulation of DNA-templated transcription [GO:0045893]; RNA splicing [GO:0008380] | cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] | DNA binding [GO:0003677]; metal ion binding [GO:0046872]; mRNA 3'-UTR binding [GO:0003730]; RNA binding [GO:0003723]; transcription coregulator activity [GO:0003712] | 23958.063694258053 | 0.156420553063032 | 0.485558433668326 | 0.842368060368871 |
| Q9NVH0 | Q9NVH0 | EXD2_HUMAN | Exonuclease 3'-5' domain-containing protein 2 (EC 3.1.11.1) (3'-5' exoribonuclease EXD2) (EC 3.1.13.-) (Exonuclease 3'-5' domain-like-containing protein 2) | EXD2 | DNA double-strand break processing [GO:0000729]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; nucleic acid metabolic process [GO:0090304]; replication fork processing [GO:0031297] | cytoplasm [GO:0005737]; intermediate filament cytoskeleton [GO:0045111]; mitochondrial matrix [GO:0005759]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; site of DNA damage [GO:0090734] | 3'-5' exonuclease activity [GO:0008408]; 3'-5'-DNA exonuclease activity [GO:0008296]; 3'-5'-RNA exonuclease activity [GO:0000175]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; nucleic acid binding [GO:0003676]; protein homodimerization activity [GO:0042803]; single-stranded DNA 3'-5' DNA exonuclease activity [GO:0008310] | 6110.059104699256 | -0.103853488563582 | 0.485877922595376 | 0.842664312649342 |
| P21359 | P21359 | NF1_HUMAN | Neurofibromin (Neurofibromatosis-related protein NF-1) [Cleaved into: Neurofibromin truncated] | NF1 | actin cytoskeleton organization [GO:0030036]; adrenal gland development [GO:0030325]; amygdala development [GO:0021764]; angiogenesis [GO:0001525]; artery morphogenesis [GO:0048844]; brain development [GO:0007420]; camera-type eye morphogenesis [GO:0048593]; cell communication [GO:0007154]; cellular response to heat [GO:0034605]; cerebral cortex development [GO:0021987]; cognition [GO:0050890]; collagen fibril organization [GO:0030199]; endothelial cell proliferation [GO:0001935]; extracellular matrix organization [GO:0030198]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; fibroblast proliferation [GO:0048144]; forebrain astrocyte development [GO:0021897]; forebrain morphogenesis [GO:0048853]; gamma-aminobutyric acid secretion, neurotransmission [GO:0061534]; glutamate secretion, neurotransmission [GO:0061535]; hair follicle maturation [GO:0048820]; heart development [GO:0007507]; liver development [GO:0001889]; long-term synaptic potentiation [GO:0060291]; MAPK cascade [GO:0000165]; mast cell apoptotic process [GO:0033024]; mast cell proliferation [GO:0070662]; metanephros development [GO:0001656]; myelination in peripheral nervous system [GO:0022011]; myeloid leukocyte migration [GO:0097529]; negative regulation of angiogenesis [GO:0016525]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of mast cell proliferation [GO:0070667]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of neurotransmitter secretion [GO:0046929]; negative regulation of oligodendrocyte differentiation [GO:0048715]; negative regulation of osteoclast differentiation [GO:0045671]; negative regulation of protein import into nucleus [GO:0042308]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of Rac protein signal transduction [GO:0035021]; negative regulation of Ras protein signal transduction [GO:0046580]; negative regulation of Schwann cell migration [GO:1900148]; negative regulation of Schwann cell proliferation [GO:0010626]; negative regulation of stem cell proliferation [GO:2000647]; negative regulation of vascular associated smooth muscle cell migration [GO:1904753]; neural tube development [GO:0021915]; neuroblast proliferation [GO:0007405]; neuron apoptotic process [GO:0051402]; observational learning [GO:0098597]; oligodendrocyte differentiation [GO:0048709]; osteoblast differentiation [GO:0001649]; osteoclast differentiation [GO:0030316]; peripheral nervous system development [GO:0007422]; phosphatidylinositol 3-kinase/protein kinase B signal transduction [GO:0043491]; pigmentation [GO:0043473]; positive regulation of adenylate cyclase activity [GO:0045762]; positive regulation of apoptotic process [GO:0043065]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; positive regulation of GTPase activity [GO:0043547]; positive regulation of mast cell apoptotic process [GO:0033027]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of vascular associated smooth muscle cell proliferation [GO:1904707]; protein import into nucleus [GO:0006606]; Rac protein signal transduction [GO:0016601]; Ras protein signal transduction [GO:0007265]; regulation of angiogenesis [GO:0045765]; regulation of blood vessel endothelial cell migration [GO:0043535]; regulation of bone resorption [GO:0045124]; regulation of cell-matrix adhesion [GO:0001952]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of gene expression [GO:0010468]; regulation of glial cell differentiation [GO:0045685]; regulation of GTPase activity [GO:0043087]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of long-term synaptic potentiation [GO:1900271]; regulation of postsynapse organization [GO:0099175]; regulation of synaptic transmission, GABAergic [GO:0032228]; response to hypoxia [GO:0001666]; Schwann cell development [GO:0014044]; Schwann cell migration [GO:0036135]; Schwann cell proliferation [GO:0014010]; skeletal muscle tissue development [GO:0007519]; smooth muscle tissue development [GO:0048745]; spinal cord development [GO:0021510]; stem cell proliferation [GO:0072089]; sympathetic nervous system development [GO:0048485]; vascular associated smooth muscle cell migration [GO:1904738]; vascular associated smooth muscle cell proliferation [GO:1990874]; visual learning [GO:0008542]; wound healing [GO:0042060] | axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; presynapse [GO:0098793] | GTPase activator activity [GO:0005096]; phosphatidylcholine binding [GO:0031210]; phosphatidylethanolamine binding [GO:0008429] | 5103.41186049894 | -0.58474247785467 | 0.48683969088045 | 0.844073956098112 |
| Q8IZ83 | Q8IZ83 | A16A1_HUMAN | Aldehyde dehydrogenase family 16 member A1 | ALDH16A1 | membrane [GO:0016020] | phenylacetaldehyde dehydrogenase activity [GO:0008957] | 10601.7369195596 | -0.209040474918682 | 0.487109144338276 | 0.844282781223821 | |
| Q9NQP4 | Q9NQP4 | PFD4_HUMAN | Prefoldin subunit 4 (Protein C-1) | PFDN4 | chaperone-mediated protein folding [GO:0061077]; negative regulation of amyloid fibril formation [GO:1905907]; protein folding [GO:0006457] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; prefoldin complex [GO:0016272] | amyloid-beta binding [GO:0001540]; protein-folding chaperone binding [GO:0051087]; unfolded protein binding [GO:0051082] | 32676.25656609125 | 0.198396813938396 | 0.48783218668248 | 0.845019567841213 |
| A6NCE7;Q9GZQ8 | A6NCE7 | MP3B2_HUMAN | Microtubule-associated proteins 1A/1B light chain 3 beta 2 (Microtubule-associated proteins 1A/1B light chain 3B-like) | MAP1LC3B2 | autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; cellular response to nitrogen starvation [GO:0006995] | autophagosome membrane [GO:0000421]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endomembrane system [GO:0012505]; intracellular membrane-bounded organelle [GO:0043231]; microtubule [GO:0005874] | microtubule binding [GO:0008017]; phosphatidylethanolamine binding [GO:0008429]; ubiquitin protein ligase binding [GO:0031625] | 162379.6042093735 | 0.172549414469314 | 0.488213881061274 | 0.845301010464915 |
| Q8IWE4 | Q8IWE4 | DCNL3_HUMAN | DCN1-like protein 3 (DCNL3) (DCUN1 domain-containing protein 3) (Defective in cullin neddylation protein 1-like protein 3) (Squamous cell carcinoma-related oncogene 3) | DCUN1D3 | negative regulation of cell growth [GO:0030308]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of protein neddylation [GO:2000435]; positive regulation of apoptotic process [GO:0043065]; positive regulation of protein neddylation [GO:2000436]; protein neddylation [GO:0045116]; regulation of cell cycle process [GO:0010564]; regulation of protein neddylation [GO:2000434]; response to gamma radiation [GO:0010332]; response to UV-C [GO:0010225] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ubiquitin ligase complex [GO:0000151] | cullin family protein binding [GO:0097602]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin-like protein binding [GO:0032182] | 4966.26860338929 | 0.145490391392743 | 0.48874623110424 | 0.845598353134879 |
| Q15208 | Q15208 | STK38_HUMAN | Serine/threonine-protein kinase 38 (EC 2.7.11.1) (NDR1 protein kinase) (Nuclear Dbf2-related kinase 1) | STK38 | intracellular signal transduction [GO:0035556]; negative regulation of MAP kinase activity [GO:0043407]; postsynapse organization [GO:0099173]; protein modification process [GO:0036211]; protein phosphorylation [GO:0006468] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; nucleus [GO:0005634] | ATP binding [GO:0005524]; cadherin binding [GO:0045296]; magnesium ion binding [GO:0000287]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] | 8839.459219515331 | 0.0918725188082319 | 0.488763608633379 | 0.845598353134879 |
| Q9Y3C0 | Q9Y3C0 | WASC3_HUMAN | WASH complex subunit 3 (Coiled-coil domain-containing protein 53) | WASHC3 | actin filament polymerization [GO:0030041]; endosomal transport [GO:0016197]; exocytosis [GO:0006887]; protein transport [GO:0015031]; regulation of Arp2/3 complex-mediated actin nucleation [GO:0034315] | early endosome membrane [GO:0031901]; WASH complex [GO:0071203] | 17094.56769917735 | 0.193067144941726 | 0.489607242671831 | 0.846381147377521 | |
| O95487 | O95487 | SC24B_HUMAN | Protein transport protein Sec24B (SEC24-related protein B) | SEC24B | aorta morphogenesis [GO:0035909]; auditory receptor cell stereocilium organization [GO:0060088]; cochlear nucleus development [GO:0021747]; COPII-coated vesicle cargo loading [GO:0090110]; coronary artery morphogenesis [GO:0060982]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intracellular protein transport [GO:0006886]; lung lobe morphogenesis [GO:0060463]; neural tube closure [GO:0001843]; outflow tract morphogenesis [GO:0003151]; pulmonary artery morphogenesis [GO:0061156]; regulation of cargo loading into COPII-coated vesicle [GO:1901301]; regulation of establishment of planar polarity involved in neural tube closure [GO:0090178] | COPII vesicle coat [GO:0030127]; cytosol [GO:0005829]; endoplasmic reticulum exit site [GO:0070971]; endoplasmic reticulum membrane [GO:0005789]; ER to Golgi transport vesicle membrane [GO:0012507] | SNARE binding [GO:0000149]; zinc ion binding [GO:0008270] | 9213.034878147026 | -0.179563137114805 | 0.490005052906688 | 0.846711994440164 |
| P34059 | P34059 | GALNS_HUMAN | N-acetylgalactosamine-6-sulfatase (EC 3.1.6.4) (Chondroitinsulfatase) (Chondroitinase) (Galactose-6-sulfate sulfatase) (GalN6S) (N-acetylgalactosamine-6-sulfate sulfatase) (GalNAc6S sulfatase) | GALNS | azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; lysosomal lumen [GO:0043202] | arylsulfatase activity [GO:0004065]; metal ion binding [GO:0046872]; N-acetylgalactosamine-4-sulfatase activity [GO:0003943]; N-acetylgalactosamine-6-sulfatase activity [GO:0043890]; sulfuric ester hydrolase activity [GO:0008484] | 18013.68090448005 | 0.220696543068683 | 0.490235769569055 | 0.846852399505568 | |
| O60239 | O60239 | 3BP5_HUMAN | SH3 domain-binding protein 5 (SH3BP-5) (SH3 domain-binding protein that preferentially associates with BTK) | SH3BP5 | intracellular signal transduction [GO:0035556]; signal transduction [GO:0007165] | cytoplasm [GO:0005737]; cytoplasmic vesicle membrane [GO:0030659]; mitochondrion [GO:0005739]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654] | guanyl-nucleotide exchange factor activity [GO:0005085]; protein kinase inhibitor activity [GO:0004860]; SH3 domain binding [GO:0017124] | 5176.600340257315 | 0.202039072729647 | 0.491310328229065 | 0.847933085515043 |
| O00186 | O00186 | STXB3_HUMAN | Syntaxin-binding protein 3 (Platelet Sec1 protein) (PSP) (Protein unc-18 homolog 3) (Unc18-3) (Protein unc-18 homolog C) (Unc-18C) | STXBP3 | brain development [GO:0007420]; cellular response to type II interferon [GO:0071346]; insulin secretion [GO:0030073]; intracellular glucose homeostasis [GO:0001678]; intracellular protein transport [GO:0006886]; negative regulation of calcium ion-dependent exocytosis [GO:0045955]; negative regulation of glucose import [GO:0046325]; neurotransmitter secretion [GO:0007269]; neutrophil degranulation [GO:0043312]; platelet aggregation [GO:0070527]; protein to membrane docking [GO:0022615]; response to insulin [GO:0032868]; vesicle docking involved in exocytosis [GO:0006904]; vesicle-mediated transport [GO:0016192] | apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; presynapse [GO:0098793]; secretory granule [GO:0030141]; specific granule [GO:0042581]; tertiary granule [GO:0070820] | protein-containing complex binding [GO:0044877]; syntaxin binding [GO:0019905]; syntaxin-1 binding [GO:0017075] | 16923.93149611315 | -0.143296944199369 | 0.491068311908537 | 0.847933085515043 |
| Q3KQV9 | Q3KQV9 | UAP1L_HUMAN | UDP-N-acetylhexosamine pyrophosphorylase-like protein 1 (EC 2.7.7.-) | UAP1L1 | UDP-N-acetylglucosamine biosynthetic process [GO:0006048] | UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977] | 13622.955970758001 | -0.138915229699305 | 0.491302445989887 | 0.847933085515043 | |
| Q92785 | Q92785 | REQU_HUMAN | Zinc finger protein ubi-d4 (Apoptosis response zinc finger protein) (BRG1-associated factor 45D) (BAF45D) (D4, zinc and double PHD fingers family 2) (Protein requiem) | DPF2 | apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; chromatin remodeling [GO:0006338]; negative regulation of myeloid progenitor cell differentiation [GO:1905454]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; positive regulation of double-strand break repair [GO:2000781]; positive regulation of stem cell population maintenance [GO:1902459]; regulation of G0 to G1 transition [GO:0070316]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of mitotic metaphase/anaphase transition [GO:0030071]; regulation of nucleotide-excision repair [GO:2000819]; regulation of transcription by RNA polymerase II [GO:0006357] | centrosome [GO:0005813]; chromatin [GO:0000785]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nBAF complex [GO:0071565]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; SWI/SNF complex [GO:0016514] | H3K9me3 modified histone binding [GO:0062072]; lysine-acetylated histone binding [GO:0070577]; metal ion binding [GO:0046872]; transcription corepressor activity [GO:0003714] | 9837.419338833055 | 0.240622834996966 | 0.491994199645593 | 0.848713847775332 |
| O60645 | O60645 | EXOC3_HUMAN | Exocyst complex component 3 (Exocyst complex component Sec6) | EXOC3 | exocyst localization [GO:0051601]; exocytosis [GO:0006887]; membrane fission [GO:0090148]; mitotic cytokinesis [GO:0000281]; protein transport [GO:0015031]; vesicle docking involved in exocytosis [GO:0006904]; vesicle tethering involved in exocytosis [GO:0090522] | cytosol [GO:0005829]; exocyst [GO:0000145]; Golgi apparatus [GO:0005794]; growth cone [GO:0030426]; midbody [GO:0030496]; perinuclear region of cytoplasm [GO:0048471]; presynaptic membrane [GO:0042734]; secretory granule membrane [GO:0030667] | cadherin binding [GO:0045296]; SNARE binding [GO:0000149] | 12345.598890059351 | -0.135893534541686 | 0.492062299672073 | 0.848713847775332 |
| O60936 | O60936 | NOL3_HUMAN | Nucleolar protein 3 (Apoptosis repressor with CARD) (Muscle-enriched cytoplasmic protein) (Myp) (Nucleolar protein of 30 kDa) (Nop30) | NOL3 | blood vessel remodeling [GO:0001974]; cardiac muscle cell apoptotic process [GO:0010659]; inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; intrinsic apoptotic signaling pathway [GO:0097193]; mRNA splice site recognition [GO:0006376]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiac muscle cell apoptotic process [GO:0010667]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway [GO:1903298]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902109]; negative regulation of muscle atrophy [GO:0014736]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of programmed necrotic cell death [GO:0062099]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; protein complex oligomerization [GO:0051259]; regulation of non-canonical NF-kappaB signal transduction [GO:1901222]; release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0014808]; response to hypoxia [GO:0001666]; response to injury involved in regulation of muscle adaptation [GO:0014876]; response to ischemia [GO:0002931]; RNA splicing [GO:0008380] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; sarcoplasmic reticulum [GO:0016529] | calcium ion binding [GO:0005509]; caspase binding [GO:0089720]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; death effector domain binding [GO:0035877]; death receptor binding [GO:0005123]; identical protein binding [GO:0042802]; RNA binding [GO:0003723] | 17686.18086333295 | 0.170533136123564 | 0.492701533161995 | 0.849499544219002 |
| P78362 | P78362 | SRPK2_HUMAN | SRSF protein kinase 2 (EC 2.7.11.1) (SFRS protein kinase 2) (Serine/arginine-rich protein-specific kinase 2) (SR-protein-specific kinase 2) [Cleaved into: SRSF protein kinase 2 N-terminal; SRSF protein kinase 2 C-terminal] | SRPK2 | angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; negative regulation of viral genome replication [GO:0045071]; nuclear speck organization [GO:0035063]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of viral genome replication [GO:0045070]; protein phosphorylation [GO:0006468]; R-loop processing [GO:0062176]; regulation of mRNA processing [GO:0050684]; regulation of mRNA splicing, via spliceosome [GO:0048024]; RNA splicing [GO:0008380]; spliceosomal complex assembly [GO:0000245] | chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] | 14-3-3 protein binding [GO:0071889]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; RNA binding [GO:0003723] | 8849.16826658925 | -0.159258128132313 | 0.492817684759594 | 0.849499544219002 |
| Q8TDM6 | Q8TDM6 | DLG5_HUMAN | Disks large homolog 5 (Discs large protein P-dlg) (Placenta and prostate DLG) | DLG5 | apical protein localization [GO:0045176]; cell-cell adhesion [GO:0098609]; epithelial to mesenchymal transition [GO:0001837]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; intracellular signal transduction [GO:0035556]; maintenance of cell polarity [GO:0030011]; metanephric collecting duct development [GO:0072205]; midbrain development [GO:0030901]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of hippo signaling [GO:0035331]; negative regulation of T cell proliferation [GO:0042130]; neuroepithelial cell differentiation [GO:0060563]; polarized epithelial cell differentiation [GO:0030859]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of hippo signaling [GO:0035332]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of synapse assembly [GO:0051965]; postsynapse organization [GO:0099173]; protein localization to adherens junction [GO:0071896]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981]; signal transduction [GO:0007165]; zonula adherens assembly [GO:0045186] | adherens junction [GO:0005912]; cell junction [GO:0030054]; ciliary basal body [GO:0036064]; cytoplasm [GO:0005737]; glutamatergic synapse [GO:0098978]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069] | beta-catenin binding [GO:0008013]; cytoskeletal protein binding [GO:0008092]; signaling receptor complex adaptor activity [GO:0030159] | 16678.301337313147 | -0.563144539002989 | 0.493396986015958 | 0.850239453396112 |
| O14730 | O14730 | RIOK3_HUMAN | Serine/threonine-protein kinase RIO3 (EC 2.7.11.1) (RIO kinase 3) (sudD homolog) | RIOK3 | cellular response to dsDNA [GO:1990786]; cellular response to dsRNA [GO:0071359]; cellular response to virus [GO:0098586]; chromosome segregation [GO:0007059]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; maturation of SSU-rRNA [GO:0030490]; negative regulation of canonical NF-kappaB signal transduction [GO:0043124]; negative regulation of MDA-5 signaling pathway [GO:0039534]; negative regulation of protein-containing complex assembly [GO:0031333]; phosphorylation [GO:0016310]; positive regulation of innate immune response [GO:0045089]; positive regulation of interferon-beta production [GO:0032728] | cytosol [GO:0005829]; preribosome, small subunit precursor [GO:0030688] | ATP binding [GO:0005524]; caspase binding [GO:0089720]; metal ion binding [GO:0046872]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] | 6874.18256720298 | -0.232448045387912 | 0.493879104563206 | 0.850552889500038 |
| Q8N4P3 | Q8N4P3 | MESH1_HUMAN | Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1 (EC 3.1.7.2) (HD domain-containing protein 3) (Metazoan SpoT homolog 1) (MESH1) (Penta-phosphate guanosine-3'-pyrophosphohydrolase) ((ppGpp)ase) | HDDC3 | guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity [GO:0008893]; metal ion binding [GO:0046872] | 65183.88708917115 | 0.343906827763692 | 0.494738115342797 | 0.85137220416089 | ||
| Q9UMY1 | Q9UMY1 | UTP16_HUMAN | U3 small nucleolar RNA-associated protein NOL7 (U3 snoRNA-associated protein NOL7) (Nucleolar protein 7) (Nucleolar protein of 27 kDa) | NOL7 | maturation of SSU-rRNA [GO:0030490]; ribosomal small subunit biogenesis [GO:0042274] | chromosome [GO:0005694]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; small-subunit processome [GO:0032040] | RNA binding [GO:0003723] | 11590.0319199886 | 0.192402473774932 | 0.494529555042238 | 0.85137220416089 |
| Q9Y3P9 | Q9Y3P9 | RBGP1_HUMAN | Rab GTPase-activating protein 1 (GAP and centrosome-associated protein) (Rab6 GTPase-activating protein GAPCenA) | RABGAP1 | cell cycle [GO:0007049]; regulation of GTPase activity [GO:0043087] | centrosome [GO:0005813]; cytosol [GO:0005829]; microtubule associated complex [GO:0005875] | GTPase activator activity [GO:0005096]; small GTPase binding [GO:0031267]; tubulin binding [GO:0015631] | 7453.264871314575 | -0.240892211420229 | 0.49480562447967 | 0.85137220416089 |
| Q8N5B7 | Q8N5B7 | CERS5_HUMAN | Ceramide synthase 5 (CerS5) (LAG1 longevity assurance homolog 5) (Sphingoid base N-palmitoyltransferase CERS5) (EC 2.3.1.291) (Sphingosine N-acyltransferase CERS5) (EC 2.3.1.24) | CERS5 | ceramide biosynthetic process [GO:0046513]; oligodendrocyte development [GO:0014003]; sphingolipid biosynthetic process [GO:0030148] | endoplasmic reticulum membrane [GO:0005789] | DNA binding [GO:0003677]; sphingosine N-acyltransferase activity [GO:0050291] | 1825.6890800420051 | -0.185403542558014 | 0.495516297698402 | 0.852043562659497 |
| Q9NRA8 | Q9NRA8 | 4ET_HUMAN | Eukaryotic translation initiation factor 4E transporter (4E-T) (eIF4E transporter) (Eukaryotic translation initiation factor 4E nuclear import factor 1) | EIF4ENIF1 | miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; mRNA stabilization [GO:0048255]; negative regulation of deadenylation-dependent decapping of nuclear-transcribed mRNA [GO:0106289]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of translation [GO:0017148]; neuron differentiation [GO:0030182]; P-body assembly [GO:0033962]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; protein import into nucleus [GO:0006606]; stem cell population maintenance [GO:0019827]; translation [GO:0006412] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nuclear speck [GO:0016607]; nucleus [GO:0005634]; P-body [GO:0000932]; PML body [GO:0016605] | kinase binding [GO:0019900]; mRNA binding [GO:0003729]; nuclear export signal receptor activity [GO:0005049]; RNA binding [GO:0003723] | 3973.1323005133454 | -0.217682449226826 | 0.495646943615549 | 0.852043562659497 |
| Q9H6U6 | Q9H6U6 | BCAS3_HUMAN | BCAS3 microtubule associated cell migration factor (Breast carcinoma-amplified sequence 3) (GAOB1) | BCAS3 | angiogenesis [GO:0001525]; autophagy [GO:0006914]; cell-cell signaling [GO:0007267]; cellular response to estrogen stimulus [GO:0071391]; positive regulation of catalytic activity [GO:0043085]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of actin cytoskeleton organization [GO:0032956]; response to estrogen [GO:0043627]; response to starvation [GO:0042594] | cell leading edge [GO:0031252]; cytoplasm [GO:0005737]; cytoplasmic microtubule [GO:0005881]; euchromatin [GO:0000791]; intermediate filament cytoskeleton [GO:0045111]; nucleus [GO:0005634]; phagophore assembly site [GO:0000407] | acetyltransferase activator activity [GO:0010698]; beta-tubulin binding [GO:0048487]; chromatin binding [GO:0003682]; histone acetyltransferase binding [GO:0035035]; histone binding [GO:0042393]; nuclear receptor binding [GO:0016922]; phosphatidylinositol binding [GO:0035091] | 8885.783837131126 | -0.264203428226935 | 0.495968886811544 | 0.852338402388295 |
| Q9NRG0 | Q9NRG0 | CHRC1_HUMAN | Chromatin accessibility complex protein 1 (CHRAC-1) (Chromatin accessibility complex 15 kDa protein) (CHRAC-15) (HuCHRAC15) (DNA polymerase epsilon subunit p15) | CHRAC1 | chromatin remodeling [GO:0006338]; DNA-templated DNA replication [GO:0006261]; nucleosome assembly [GO:0006334]; regulation of DNA replication [GO:0006275]; regulation of DNA-templated transcription [GO:0006355] | CHRAC [GO:0008623]; epsilon DNA polymerase complex [GO:0008622]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721] | DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; protein heterodimerization activity [GO:0046982]; transcription cis-regulatory region binding [GO:0000976] | 3101.9747167977202 | 0.307167962197925 | 0.496925252667644 | 0.853420230662145 |
| P18859 | P18859 | ATP5J_HUMAN | ATP synthase-coupling factor 6, mitochondrial (ATPase subunit F6) (ATP synthase peripheral stalk subunit F6) | ATP5PF | proton motive force-driven ATP synthesis [GO:0015986]; proton motive force-driven mitochondrial ATP synthesis [GO:0042776]; substantia nigra development [GO:0021762] | mitochondrial inner membrane [GO:0005743]; mitochondrial proton-transporting ATP synthase complex [GO:0005753]; mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) [GO:0000276]; mitochondrion [GO:0005739] | proton transmembrane transporter activity [GO:0015078] | 84277.33524793206 | 0.182250278619948 | 0.497414850713507 | 0.85378750201234 |
| Q9NY33 | Q9NY33 | DPP3_HUMAN | Dipeptidyl peptidase 3 (EC 3.4.14.4) (Dipeptidyl aminopeptidase III) (Dipeptidyl arylamidase III) (Dipeptidyl peptidase III) (DPP III) (Enkephalinase B) | DPP3 | protein catabolic process [GO:0030163]; proteolysis [GO:0006508] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062] | aminopeptidase activity [GO:0004177]; dipeptidyl-peptidase activity [GO:0008239]; metalloexopeptidase activity [GO:0008235]; zinc ion binding [GO:0008270] | 31325.97406642125 | 0.0793312296410833 | 0.497876354264605 | 0.854062192934681 |
| P17706 | P17706 | PTN2_HUMAN | Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (T-cell protein-tyrosine phosphatase) (TCPTP) | PTPN2 | B cell differentiation [GO:0030183]; erythrocyte differentiation [GO:0030218]; glucose homeostasis [GO:0042593]; insulin receptor recycling [GO:0038020]; insulin receptor signaling pathway [GO:0008286]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of chemotaxis [GO:0050922]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of inflammatory response [GO:0050728]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of interleukin-2-mediated signaling pathway [GO:1902206]; negative regulation of interleukin-4-mediated signaling pathway [GO:1902215]; negative regulation of interleukin-6-mediated signaling pathway [GO:0070104]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage colony-stimulating factor signaling pathway [GO:1902227]; negative regulation of macrophage differentiation [GO:0045650]; negative regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000587]; negative regulation of positive thymic T cell selection [GO:1902233]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of T cell receptor signaling pathway [GO:0050860]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; negative regulation of type II interferon-mediated signaling pathway [GO:0060336]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; peptidyl-tyrosine dephosphorylation [GO:0035335]; positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902237]; positive regulation of gluconeogenesis [GO:0045722]; positive regulation of PERK-mediated unfolded protein response [GO:1903899]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of type II interferon-mediated signaling pathway [GO:0060334]; T cell differentiation [GO:0030217] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endosome lumen [GO:0031904]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886] | integrin binding [GO:0005178]; non-membrane spanning protein tyrosine phosphatase activity [GO:0004726]; protein kinase binding [GO:0019901]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; STAT family protein binding [GO:0097677]; syntaxin binding [GO:0019905] | 7166.011400892556 | 0.169561723528594 | 0.499054628116362 | 0.855824310807297 |
| Q92522 | Q92522 | H1X_HUMAN | Histone H1.10 (Histone H1x) | H1-10 | chromosome condensation [GO:0030261]; negative regulation of DNA recombination [GO:0045910]; nucleosome assembly [GO:0006334] | chromosome [GO:0005694]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634] | cadherin binding [GO:0045296]; double-stranded DNA binding [GO:0003690]; nucleosomal DNA binding [GO:0031492]; RNA binding [GO:0003723]; structural constituent of chromatin [GO:0030527] | 37029.3220848578 | -0.210999489909625 | 0.499384462533769 | 0.856130821396774 |
| O95182 | O95182 | NDUA7_HUMAN | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 (Complex I-B14.5a) (CI-B14.5a) (NADH-ubiquinone oxidoreductase subunit B14.5a) | NDUFA7 | aerobic respiration [GO:0009060]; mitochondrial electron transport, NADH to ubiquinone [GO:0006120]; mitochondrial translation [GO:0032543]; proton motive force-driven mitochondrial ATP synthesis [GO:0042776] | mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex I [GO:0005747]; mitochondrial ribosome [GO:0005761]; mitochondrion [GO:0005739] | NADH dehydrogenase (ubiquinone) activity [GO:0008137]; structural constituent of ribosome [GO:0003735] | 4489.74748291457 | -0.0906445383831639 | 0.501514687191681 | 0.859262841738151 |
| Q13085 | Q13085 | ACACA_HUMAN | Acetyl-CoA carboxylase 1 (ACC1) (EC 6.4.1.2) (Acetyl-Coenzyme A carboxylase alpha) (ACC-alpha) | ACACA | acetyl-CoA metabolic process [GO:0006084]; cellular response to prostaglandin E stimulus [GO:0071380]; fatty acid biosynthetic process [GO:0006633]; fatty-acyl-CoA biosynthetic process [GO:0046949]; lipid homeostasis [GO:0055088]; malonyl-CoA biosynthetic process [GO:2001295]; protein homotetramerization [GO:0051289]; protein metabolic process [GO:0019538]; tissue homeostasis [GO:0001894] | actin cytoskeleton [GO:0015629]; cytosol [GO:0005829]; fibrillar center [GO:0001650]; mitochondrion [GO:0005739] | acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872] | 8835.83549867567 | -0.222758488470677 | 0.502451031693106 | 0.86059904522466 |
| Q15283 | Q15283 | RASA2_HUMAN | Ras GTPase-activating protein 2 (GTPase-activating protein 1m) (GAP1m) | RASA2 | intracellular signal transduction [GO:0035556]; negative regulation of Ras protein signal transduction [GO:0046580]; signal transduction [GO:0007165] | cytosol [GO:0005829]; perinuclear region of cytoplasm [GO:0048471] | GTPase activator activity [GO:0005096]; metal ion binding [GO:0046872]; phospholipid binding [GO:0005543] | 7183.80268133116 | 0.321879317440363 | 0.503985961964268 | 0.862453778462563 |
| Q8N1B4 | Q8N1B4 | VPS52_HUMAN | Vacuolar protein sorting-associated protein 52 homolog (SAC2 suppressor of actin mutations 2-like protein) | VPS52 | ectodermal cell differentiation [GO:0010668]; embryonic ectodermal digestive tract development [GO:0048611]; endocytic recycling [GO:0032456]; Golgi to vacuole transport [GO:0006896]; lysosomal transport [GO:0007041]; protein targeting [GO:0006605]; protein transport [GO:0015031]; retrograde transport, endosome to Golgi [GO:0042147]; vesicle-mediated cholesterol transport [GO:0090119] | cytosol [GO:0005829]; EARP complex [GO:1990745]; endosome membrane [GO:0010008]; GARP complex [GO:0000938]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; trans-Golgi network membrane [GO:0032588] | syntaxin binding [GO:0019905] | 5300.63630051578 | -0.328328298287701 | 0.504755308930134 | 0.863248892362855 |
| Q9UKF6 | Q9UKF6 | CPSF3_HUMAN | Cleavage and polyadenylation specificity factor subunit 3 (EC 3.1.27.-) (Cleavage and polyadenylation specificity factor 73 kDa subunit) (CPSF 73 kDa subunit) (mRNA 3'-end-processing endonuclease CPSF-73) | CPSF3 | co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway [GO:0180010]; mRNA 3'-end processing [GO:0031124]; mRNA 3'-end processing by stem-loop binding and cleavage [GO:0006398]; mRNA polyadenylation [GO:0006378]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087] | mRNA cleavage and polyadenylation specificity factor complex [GO:0005847]; nucleoplasm [GO:0005654]; ribonucleoprotein complex [GO:1990904] | 5'-3' RNA exonuclease activity [GO:0004534]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA endonuclease activity [GO:0004521] | 5917.21364529729 | 0.219884422211722 | 0.506026958791131 | 0.865042246346012 |
| Q9H446 | Q9H446 | RWDD1_HUMAN | RWD domain-containing protein 1 (DRG family-regulatory protein 2) | RWDD1 | androgen receptor signaling pathway [GO:0030521]; cellular response to oxidative stress [GO:0034599]; cellular response to testosterone stimulus [GO:0071394]; cytoplasmic translation [GO:0002181] | cytosol [GO:0005829] | 21243.84352945945 | 0.222919073285143 | 0.506109256377873 | 0.865042246346012 | |
| Q7RTS9 | Q7RTS9 | DYM_HUMAN | Dymeclin (Dyggve-Melchior-Clausen syndrome protein) | DYM | bone development [GO:0060348]; Golgi organization [GO:0007030] | cytoplasm [GO:0005737]; Golgi apparatus [GO:0005794]; membrane [GO:0016020] | enzyme binding [GO:0019899] | 1235.7137897906 | -2.27129462575494 | 0.507209770147366 | 0.866417754166947 |
| Q8N9N8 | Q8N9N8 | EIF1A_HUMAN | Probable RNA-binding protein EIF1AD (Eukaryotic translation initiation factor 1A domain-containing protein) (Haponin) | EIF1AD | cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] | RNA binding [GO:0003723]; translation initiation factor activity [GO:0003743] | 17924.38346293995 | 0.188350764898022 | 0.507219853613089 | 0.866417754166947 | |
| Q9BY76 | Q9BY76 | ANGL4_HUMAN | Angiopoietin-related protein 4 (Angiopoietin-like protein 4) (Hepatic fibrinogen/angiopoietin-related protein) (HFARP) [Cleaved into: ANGPTL4 N-terminal chain; ANGPTL4 C-terminal chain] | ANGPTL4 | angiogenesis [GO:0001525]; endothelial cell apoptotic process [GO:0072577]; lipid metabolic process [GO:0006629]; negative regulation of apoptotic process [GO:0043066]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of lipoprotein lipase activity [GO:0051005]; positive regulation of angiogenesis [GO:0045766]; protein unfolding [GO:0043335]; response to hypoxia [GO:0001666]; triglyceride homeostasis [GO:0070328] | blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615] | enzyme inhibitor activity [GO:0004857]; identical protein binding [GO:0042802] | 5136.794541095505 | 0.223019696041828 | 0.507532121904415 | 0.866689874234603 |
| Q9Y295 | Q9Y295 | DRG1_HUMAN | Developmentally-regulated GTP-binding protein 1 (DRG-1) (Neural precursor cell expressed developmentally down-regulated protein 3) (NEDD-3) (Translation factor GTPase DRG1) (TRAFAC GTPase DRG1) (EC 3.6.5.-) | DRG1 | cytoplasmic translation [GO:0002181]; positive regulation of microtubule polymerization [GO:0031116]; regulation of mitotic spindle assembly [GO:1901673] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] | GTP binding [GO:0005525]; GTPase activity [GO:0003924]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; potassium ion binding [GO:0030955] | 18612.96855197385 | 0.0976977823755254 | 0.509188372666446 | 0.866778761328194 |
| P63172 | P63172 | DYLT1_HUMAN | Dynein light chain Tctex-type 1 (Protein CW-1) (T-complex testis-specific protein 1 homolog) | DYNLT1 | cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; intracellular transport of viral protein in host cell [GO:0019060]; microtubule-based movement [GO:0007018]; microtubule-dependent intracellular transport of viral material towards nucleus [GO:0075521]; negative regulation of neurogenesis [GO:0050768]; nervous system development [GO:0007399]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]; symbiont entry into host cell [GO:0046718] | cytoplasm [GO:0005737]; cytoplasmic dynein complex [GO:0005868]; cytoplasmic microtubule [GO:0005881]; dynein complex [GO:0030286]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; Golgi apparatus [GO:0005794]; host cell [GO:0043657]; secretory granule lumen [GO:0034774]; secretory vesicle [GO:0099503]; spindle [GO:0005819] | dynein intermediate chain binding [GO:0045505]; identical protein binding [GO:0042802] | 11354.9157946223 | -0.400943952310658 | 0.508983841372868 | 0.866778761328194 |
| Q6NYC1 | Q6NYC1 | JMJD6_HUMAN | Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 (EC 1.14.11.-) (Histone arginine demethylase JMJD6) (JmjC domain-containing protein 6) (Jumonji domain-containing protein 6) (Lysyl-hydroxylase JMJD6) (Peptide-lysine 5-dioxygenase JMJD6) (Phosphatidylserine receptor) (Protein PTDSR) | JMJD6 | cell surface receptor signaling pathway [GO:0007166]; chromatin remodeling [GO:0006338]; erythrocyte development [GO:0048821]; heart development [GO:0007507]; kidney development [GO:0001822]; lung development [GO:0030324]; macrophage activation [GO:0042116]; mRNA processing [GO:0006397]; negative regulation of protein homooligomerization [GO:0032463]; non-membrane-bounded organelle assembly [GO:0140694]; oxidative RNA demethylation [GO:0035513]; peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine [GO:0018395]; phagocytosis [GO:0006909]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein homooligomerization [GO:0051260]; recognition of apoptotic cell [GO:0043654]; regulation of mRNA splicing, via spliceosome [GO:0048024]; retina development in camera-type eye [GO:0060041]; RNA splicing [GO:0008380]; sprouting angiogenesis [GO:0002040]; T cell differentiation in thymus [GO:0033077] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ribonucleoprotein complex [GO:1990904] | histone demethylase activity [GO:0032452]; histone H3R2 demethylase activity [GO:0033746]; histone H4R3 demethylase activity [GO:0033749]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidative RNA demethylase activity [GO:0035515]; P-TEFb complex binding [GO:0106140]; peptidyl-lysine 5-dioxygenase activity [GO:0070815]; protein demethylase activity [GO:0140457]; RNA binding [GO:0003723]; signaling receptor activity [GO:0038023]; single-stranded RNA binding [GO:0003727]; transcription regulator activator activity [GO:0140537] | 9283.00377210566 | 0.263985172518675 | 0.508092603257446 | 0.866778761328194 |
| Q9BSV6 | Q9BSV6 | SEN34_HUMAN | tRNA-splicing endonuclease subunit Sen34 (EC 4.6.1.16) (Leukocyte receptor cluster member 5) (tRNA-intron endonuclease Sen34) (HsSen34) | TSEN34 | mRNA processing [GO:0006397]; tRNA-type intron splice site recognition and cleavage [GO:0000379] | nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; tRNA-intron endonuclease complex [GO:0000214] | lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; tRNA-intron endonuclease activity [GO:0000213] | 9798.059241970834 | 0.134204102083183 | 0.509259208230182 | 0.866778761328194 |
| Q8IX04 | Q8IX04 | UEVLD_HUMAN | Ubiquitin-conjugating enzyme E2 variant 3 (UEV-3) (EV and lactate/malate dehydrogenase domain-containing protein) | UEVLD | endosome to lysosome transport [GO:0008333]; lactate metabolic process [GO:0006089]; protein modification process [GO:0036211]; protein transport [GO:0015031]; pyruvate metabolic process [GO:0006090] | ESCRT I complex [GO:0000813]; extracellular exosome [GO:0070062] | L-lactate dehydrogenase activity [GO:0004459]; ubiquitin binding [GO:0043130] | 2679.9292540343504 | -1.70215301775064 | 0.508575291781771 | 0.866778761328194 |
| P50552 | P50552 | VASP_HUMAN | Vasodilator-stimulated phosphoprotein (VASP) | VASP | actin cytoskeleton organization [GO:0030036]; actin polymerization or depolymerization [GO:0008154]; axon guidance [GO:0007411]; neural tube closure [GO:0001843]; positive regulation of actin filament polymerization [GO:0030838]; protein homotetramerization [GO:0051289] | actin cytoskeleton [GO:0015629]; bicellular tight junction [GO:0005923]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; filopodium membrane [GO:0031527]; focal adhesion [GO:0005925]; lamellipodium membrane [GO:0031258]; plasma membrane [GO:0005886] | actin binding [GO:0003779]; cadherin binding [GO:0045296]; profilin binding [GO:0005522]; SH3 domain binding [GO:0017124] | 81860.9014453584 | 0.142328815536692 | 0.509161966275285 | 0.866778761328194 |
| P19784 | P19784 | CSK22_HUMAN | Casein kinase II subunit alpha' (CK II alpha') (EC 2.7.11.1) | CSNK2A2 | apoptotic process [GO:0006915]; cell cycle [GO:0007049]; cerebral cortex development [GO:0021987]; double-strand break repair [GO:0006302]; liver regeneration [GO:0097421]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of ubiquitin-dependent protein catabolic process [GO:2000059]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of protein targeting to mitochondrion [GO:1903955]; regulation of chromosome separation [GO:1905818]; regulation of mitophagy [GO:1901524]; spermatogenesis [GO:0007283]; Wnt signaling pathway [GO:0016055] | acrosomal vesicle [GO:0001669]; chromatin [GO:0000785]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein kinase CK2 complex [GO:0005956] | ATP binding [GO:0005524]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] | 24612.2979005841 | 0.0812804398199424 | 0.510530944754223 | 0.868300908940153 |
| P60520 | P60520 | GBRL2_HUMAN | Gamma-aminobutyric acid receptor-associated protein-like 2 (GABA(A) receptor-associated protein-like 2) (Ganglioside expression factor 2) (GEF-2) (General protein transport factor p16) (Golgi-associated ATPase enhancer of 16 kDa) (GATE-16) (MAP1 light chain 3-related protein) | GABARAPL2 | autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to nitrogen starvation [GO:0006995]; intra-Golgi vesicle-mediated transport [GO:0006891]; negative regulation of proteasomal protein catabolic process [GO:1901799]; positive regulation of ATP-dependent activity [GO:0032781]; protein localization to endoplasmic reticulum [GO:0070972]; protein transport [GO:0015031] | autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139] | ATPase binding [GO:0051117]; beta-tubulin binding [GO:0048487]; GABA receptor binding [GO:0050811]; microtubule binding [GO:0008017]; phosphatidylethanolamine binding [GO:0008429]; SNARE binding [GO:0000149]; ubiquitin protein ligase binding [GO:0031625] | 10921.5924662519 | 0.333772984687841 | 0.510446904257907 | 0.868300908940153 |
| Q9P035 | Q9P035 | HACD3_HUMAN | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 (EC 4.2.1.134) (3-hydroxyacyl-CoA dehydratase 3) (HACD3) (Butyrate-induced protein 1) (B-ind1) (hB-ind1) (Protein-tyrosine phosphatase-like A domain-containing protein 1) | HACD3 | canonical NF-kappaB signal transduction [GO:0007249]; fatty acid elongation [GO:0030497]; JNK cascade [GO:0007254]; negative regulation of intracellular signal transduction [GO:1902532]; positive regulation by virus of viral protein levels in host cell [GO:0046726]; positive regulation of viral genome replication [GO:0045070]; Rac protein signal transduction [GO:0016601]; Rho protein signal transduction [GO:0007266]; small GTPase-mediated signal transduction [GO:0007264]; sphingolipid biosynthetic process [GO:0030148]; very long-chain fatty acid biosynthetic process [GO:0042761] | endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; focal adhesion [GO:0005925]; nuclear membrane [GO:0031965] | 3-hydroxyacyl-CoA dehydratase activity [GO:0018812]; enzyme binding [GO:0019899]; GTPase activator activity [GO:0005096]; very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase activity [GO:0102158] | 61278.1527777641 | -0.0564591070673251 | 0.510621007516518 | 0.868300908940153 |
| Q9P265 | Q9P265 | DIP2B_HUMAN | Disco-interacting protein 2 homolog B (DIP2 homolog B) | DIP2B | negative regulation of axon extension [GO:0030517]; nervous system development [GO:0007399]; positive regulation of peptidyl-lysine acetylation [GO:2000758] | axon [GO:0030424]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]; perikaryon [GO:0043204] | alpha-tubulin binding [GO:0043014] | 4897.74400682136 | -0.303036490160049 | 0.511164602582397 | 0.868964487918351 |
| Q9H4G4 | Q9H4G4 | GAPR1_HUMAN | Golgi-associated plant pathogenesis-related protein 1 (GAPR-1) (Golgi-associated PR-1 protein) (Glioma pathogenesis-related protein 2) (GliPR 2) | GLIPR2 | positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374] | extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; Golgi membrane [GO:0000139] | protein homodimerization activity [GO:0042803] | 42153.03849961045 | -0.158565973179558 | 0.511382862250959 | 0.869062305443176 |
| P02768 | P02768 | ALBU_HUMAN | Albumin | ALB | cellular response to calcium ion starvation [GO:0072732]; cellular response to starvation [GO:0009267]; negative regulation of mitochondrial depolarization [GO:0051902] | blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991] | antioxidant activity [GO:0016209]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; protein-folding chaperone binding [GO:0051087]; pyridoxal phosphate binding [GO:0030170]; small molecule binding [GO:0036094]; toxic substance binding [GO:0015643] | 63349.51373159935 | 0.135865190390608 | 0.511847970641645 | 0.86908318898878 |
| Q9UQ90 | Q9UQ90 | SPG7_HUMAN | Mitochondrial inner membrane m-AAA protease component paraplegin (EC 3.4.24.-) (EC 3.6.-.-) (Cell matrix adhesion regulator) (Paraplegin) (Spastic paraplegia 7 protein) | SPG7 | anterograde axonal transport [GO:0008089]; mitochondrial outer membrane permeabilization involved in programmed cell death [GO:1902686]; mitochondrial protein processing [GO:0034982]; nervous system development [GO:0007399]; proteolysis [GO:0006508]; regulation of mitochondrial membrane permeability [GO:0046902] | axon cytoplasm [GO:1904115]; m-AAA complex [GO:0005745]; mitochondrial inner membrane [GO:0005743]; mitochondrial permeability transition pore complex [GO:0005757]; mitochondrion [GO:0005739] | ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-dependent peptidase activity [GO:0004176]; metalloendopeptidase activity [GO:0004222]; peptidase activity [GO:0008233]; unfolded protein binding [GO:0051082]; zinc ion binding [GO:0008270] | 2873.73185244142 | -0.336742286708739 | 0.511816631067027 | 0.86908318898878 |
| Q5TAT6 | Q5TAT6 | CODA1_HUMAN | Collagen alpha-1(XIII) chain (COLXIIIA1) | COL13A1 | cell differentiation [GO:0030154]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; endochondral ossification [GO:0001958]; extracellular matrix organization [GO:0030198]; morphogenesis of a branching structure [GO:0001763]; skeletal system development [GO:0001501] | cell-cell junction [GO:0005911]; collagen type XIII trimer [GO:0005600]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211] | extracellular matrix structural constituent conferring tensile strength [GO:0030020]; heparin binding [GO:0008201] | 18863.20685556295 | 0.266502038410217 | 0.51400578658204 | 0.871460686337902 |
| Q7L5Y9 | Q7L5Y9 | MAEA_HUMAN | E3 ubiquitin-protein transferase MAEA (EC 2.3.2.27) (Cell proliferation-inducing gene 5 protein) (Erythroblast macrophage protein) (Human lung cancer oncogene 10 protein) (HLC-10) (Macrophage erythroblast attacher) (P44EMLP) | MAEA | cell adhesion [GO:0007155]; cell cycle [GO:0007049]; cell division [GO:0051301]; cytoskeleton organization [GO:0007010]; enucleate erythrocyte development [GO:0048822]; erythrocyte maturation [GO:0043249]; negative regulation of myeloid cell apoptotic process [GO:0033033]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of mitotic cell cycle [GO:0007346] | actomyosin contractile ring [GO:0005826]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; GID complex [GO:0034657]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; spindle [GO:0005819]; ubiquitin ligase complex [GO:0000151] | actin binding [GO:0003779]; metal ion binding [GO:0046872]; ubiquitin protein ligase activity [GO:0061630] | 4403.92696286803 | 0.170867219576908 | 0.514017227981163 | 0.871460686337902 |
| Q8WW59 | Q8WW59 | SPRY4_HUMAN | SPRY domain-containing protein 4 | SPRYD4 | nucleus [GO:0005634] | 8570.258328996544 | -0.71104438548379 | 0.51386959876337 | 0.871460686337902 | ||
| Q9H939 | Q9H939 | PPIP2_HUMAN | Proline-serine-threonine phosphatase-interacting protein 2 (PEST phosphatase-interacting protein 2) | PSTPIP2 | actin filament polymerization [GO:0030041] | actin filament [GO:0005884]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886] | actin filament binding [GO:0051015] | 5998.347391374885 | 0.337081293964697 | 0.515454618742155 | 0.873374961062515 |
| Q15464 | Q15464 | SHB_HUMAN | SH2 domain-containing adapter protein B | SHB | angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; B cell proliferation [GO:0042100]; hematopoietic stem cell proliferation [GO:0071425]; negative regulation of oocyte maturation [GO:1900194]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of T-helper cell differentiation [GO:0045624]; signal transduction [GO:0007165]; T cell receptor signaling pathway [GO:0050852] | cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] | phosphotyrosine residue binding [GO:0001784]; signaling receptor complex adaptor activity [GO:0030159] | 6699.093626818315 | 0.255665442569346 | 0.515445505094142 | 0.873374961062515 |
| Q9H0C8 | Q9H0C8 | ILKAP_HUMAN | Integrin-linked kinase-associated serine/threonine phosphatase 2C (ILKAP) (EC 3.1.3.16) | ILKAP | negative regulation of canonical NF-kappaB signal transduction [GO:0043124]; positive regulation of canonical NF-kappaB signal transduction [GO:0043123]; positive regulation of canonical Wnt signaling pathway [GO:0090263] | cytosol [GO:0005829]; nucleus [GO:0005634] | metal ion binding [GO:0046872]; myosin phosphatase activity [GO:0017018] | 9827.345101205661 | 0.0950904238275896 | 0.516260770071344 | 0.873897881481047 |
| Q9NZQ3 | Q9NZQ3 | SPN90_HUMAN | NCK-interacting protein with SH3 domain (54 kDa VacA-interacting protein) (54 kDa vimentin-interacting protein) (VIP54) (90 kDa SH3 protein interacting with Nck) (AF3p21) (Dia-interacting protein 1) (DIP-1) (Diaphanous protein-interacting protein) (SH3 adapter protein SPIN90) (WASP-interacting SH3-domain protein) (WISH) (Wiskott-Aldrich syndrome protein-interacting protein) | NCKIPSD | actin cortical patch assembly [GO:0000147]; actin cortical patch localization [GO:0051666]; cytoskeleton organization [GO:0007010]; endocytosis [GO:0006897]; positive regulation of neuron projection development [GO:0010976] | cytosol [GO:0005829]; intermediate filament [GO:0005882]; nucleus [GO:0005634] | Arp2/3 complex binding [GO:0071933]; cytoskeletal protein binding [GO:0008092]; SH3 domain binding [GO:0017124] | 8257.94758738856 | -0.124203775516917 | 0.516309194141414 | 0.873897881481047 |
| Q9HAV4 | Q9HAV4 | XPO5_HUMAN | Exportin-5 (Exp5) (Ran-binding protein 21) | XPO5 | miRNA metabolic process [GO:0010586]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; RNA export from nucleus [GO:0006405] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RISC complex [GO:0016442]; RNA nuclear export complex [GO:0042565] | mRNA binding [GO:0003729]; nuclear export signal receptor activity [GO:0005049]; pre-miRNA binding [GO:0070883]; RISC complex binding [GO:1905172]; RNA binding [GO:0003723]; small GTPase binding [GO:0031267]; tRNA binding [GO:0000049] | 4121.8005287510805 | -0.336323727751647 | 0.516213956878475 | 0.873897881481047 |
| Q13627 | Q13627 | DYR1A_HUMAN | Dual specificity tyrosine-phosphorylation-regulated kinase 1A (EC 2.7.11.23) (EC 2.7.12.1) (Dual specificity YAK1-related kinase) (HP86) (Protein kinase minibrain homolog) (MNBH) (hMNB) | DYRK1A | amyloid-beta formation [GO:0034205]; circadian rhythm [GO:0007623]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of DNA methylation-dependent heterochromatin formation [GO:0090310]; negative regulation of microtubule polymerization [GO:0031115]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; nervous system development [GO:0007399]; peptidyl-serine autophosphorylation [GO:0036289]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of protein deacetylation [GO:0090312]; positive regulation of RNA splicing [GO:0033120]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468] | axon [GO:0030424]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; dendrite [GO:0030425]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904] | actin binding [GO:0003779]; ATP binding [GO:0005524]; cytoskeletal protein binding [GO:0008092]; histone H3T45 kinase activity [GO:0140857]; identical protein binding [GO:0042802]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protein kinase activity [GO:0004672]; protein self-association [GO:0043621]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; protein tyrosine kinase activity [GO:0004713]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; tau protein binding [GO:0048156]; tau-protein kinase activity [GO:0050321]; transcription coactivator activity [GO:0003713]; tubulin binding [GO:0015631] | 4917.277771015805 | 0.226748954052462 | 0.516551609171071 | 0.873926968516956 |
| O95299 | O95299 | NDUAA_HUMAN | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (Complex I-42kD) (CI-42kD) (NADH-ubiquinone oxidoreductase 42 kDa subunit) | NDUFA10 | aerobic respiration [GO:0009060]; mitochondrial electron transport, NADH to ubiquinone [GO:0006120]; mitochondrial respiratory chain complex I assembly [GO:0032981]; proton motive force-driven mitochondrial ATP synthesis [GO:0042776] | cytoplasm [GO:0005737]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial respiratory chain complex I [GO:0005747]; mitochondrion [GO:0005739] | deoxynucleoside kinase activity [GO:0019136]; NADH dehydrogenase (ubiquinone) activity [GO:0008137] | 32902.78094188405 | 0.0728486892637688 | 0.517767468133544 | 0.875428738161148 |
| P62424 | P62424 | RL7A_HUMAN | Large ribosomal subunit protein eL8 (60S ribosomal protein L7a) (PLA-X polypeptide) (Surfeit locus protein 3) | RPL7A | cytoplasmic translation [GO:0002181]; maturation of LSU-rRNA [GO:0000470]; translation [GO:0006412] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; cytosolic ribosome [GO:0022626]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; ribosome [GO:0005840]; synapse [GO:0045202] | cadherin binding [GO:0045296]; RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735] | 372994.5392868105 | 0.179899166730533 | 0.517920415480306 | 0.875428738161148 |
| P46782 | P46782 | RS5_HUMAN | Small ribosomal subunit protein uS7 (40S ribosomal protein S5) [Cleaved into: Small ribosomal subunit protein uS7, N-terminally processed (40S ribosomal protein S5, N-terminally processed)] | RPS5 | cytoplasmic translation [GO:0002181]; regulation of translational fidelity [GO:0006450]; ribosomal small subunit assembly [GO:0000028]; ribosomal small subunit biogenesis [GO:0042274]; translation [GO:0006412]; translational initiation [GO:0006413] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic ribosome [GO:0022626]; cytosolic small ribosomal subunit [GO:0022627]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; ribonucleoprotein complex [GO:1990904]; ribosome [GO:0005840]; small-subunit processome [GO:0032040]; synapse [GO:0045202] | mRNA binding [GO:0003729]; RNA binding [GO:0003723]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735] | 194881.69517067 | 0.140043997764267 | 0.518057281866278 | 0.875428738161148 |
| A6NHR9 | A6NHR9 | SMHD1_HUMAN | Structural maintenance of chromosomes flexible hinge domain-containing protein 1 (SMC hinge domain-containing protein 1) (EC 3.6.1.-) | SMCHD1 | chromosome organization [GO:0051276]; dosage compensation by inactivation of X chromosome [GO:0009048]; double-strand break repair [GO:0006302]; negative regulation of double-strand break repair via homologous recombination [GO:2000042]; nose development [GO:0043584]; positive regulation of DNA repair [GO:0045739]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034] | Barr body [GO:0001740]; site of double-strand break [GO:0035861] | ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; DNA binding [GO:0003677]; protein homodimerization activity [GO:0042803] | 3647.3031930665347 | -0.254559906606088 | 0.517730933650935 | 0.875428738161148 |
| Q14241 | Q14241 | ELOA1_HUMAN | Elongin-A (EloA) (Elongin 110 kDa subunit) (RNA polymerase II transcription factor SIII subunit A1) (SIII p110) (Transcription elongation factor B polypeptide 3) | ELOA | regulation of transcription by RNA polymerase II [GO:0006357]; transcription elongation by RNA polymerase II [GO:0006368]; transcription initiation at RNA polymerase II promoter [GO:0006367] | elongin complex [GO:0070449]; extracellular space [GO:0005615]; nucleoplasm [GO:0005654]; site of DNA damage [GO:0090734] | 6269.42933975073 | 0.13529718939623 | 0.518792156090855 | 0.876409170068809 | |
| Q9H497 | Q9H497 | TOR3A_HUMAN | Torsin-3A (ATP-dependent interferon-responsive protein) (Torsin family 3 member A) | TOR3A | endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; nuclear envelope [GO:0005635] | ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887] | 6995.02784671291 | -0.141174989199436 | 0.519076324724063 | 0.876627855703886 | |
| Q3MHD2 | Q3MHD2 | LSM12_HUMAN | Protein LSM12 | LSM12 | cytoplasm [GO:0005737] | RNA binding [GO:0003723] | 51086.0955186576 | 0.0712288002207917 | 0.519888256397393 | 0.877568423134696 | |
| Q9Y5X1 | Q9Y5X1 | SNX9_HUMAN | Sorting nexin-9 (SH3 and PX domain-containing protein 1) (Protein SDP1) (SH3 and PX domain-containing protein 3A) | SNX9 | cleavage furrow formation [GO:0036089]; endocytosis [GO:0006897]; endosomal transport [GO:0016197]; intracellular protein transport [GO:0006886]; lipid tube assembly [GO:0060988]; mitotic cytokinesis [GO:0000281]; plasma membrane tubulation [GO:0097320]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of GTPase activity [GO:0043547]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of protein kinase activity [GO:0045860]; protein-containing complex assembly [GO:0065003]; receptor-mediated endocytosis [GO:0006898]; regulation of synaptic vesicle endocytosis [GO:1900242] | clathrin-coated pit [GO:0005905]; clathrin-coated vesicle [GO:0030136]; cuticular plate [GO:0032437]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; plasma membrane [GO:0005886]; presynapse [GO:0098793]; ruffle [GO:0001726]; trans-Golgi network [GO:0005802] | 1-phosphatidylinositol binding [GO:0005545]; Arp2/3 complex binding [GO:0071933]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; phosphatidylinositol binding [GO:0035091]; protein homodimerization activity [GO:0042803]; ubiquitin protein ligase binding [GO:0031625] | 36322.73254290915 | 0.0620293229879398 | 0.520014273146315 | 0.877568423134696 |
| P36543 | P36543 | VATE1_HUMAN | V-type proton ATPase subunit E 1 (V-ATPase subunit E 1) (V-ATPase 31 kDa subunit) (p31) (Vacuolar proton pump subunit E 1) | ATP6V1E1 | proton transmembrane transport [GO:1902600]; regulation of macroautophagy [GO:0016241]; synaptic vesicle lumen acidification [GO:0097401] | apical plasma membrane [GO:0016324]; clathrin-coated vesicle membrane [GO:0030665]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; lysosomal membrane [GO:0005765]; microvillus [GO:0005902]; proton-transporting two-sector ATPase complex [GO:0016469]; synaptic vesicle membrane [GO:0030672]; vacuolar proton-transporting V-type ATPase, V1 domain [GO:0000221] | ATPase binding [GO:0051117]; proton-transporting ATPase activity, rotational mechanism [GO:0046961] | 60136.102218208645 | 0.135454809358374 | 0.520565429519704 | 0.877834441565073 |
| Q7L3B6 | Q7L3B6 | CD37L_HUMAN | Hsp90 co-chaperone Cdc37-like 1 (Hsp90-associating relative of Cdc37) | CDC37L1 | protein folding [GO:0006457]; protein stabilization [GO:0050821] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; platelet dense granule lumen [GO:0031089] | heat shock protein binding [GO:0031072]; protein-folding chaperone binding [GO:0051087]; unfolded protein binding [GO:0051082] | 12443.232269552449 | -0.120166166844983 | 0.520501667086853 | 0.877834441565073 |
| P24821 | P24821 | TENA_HUMAN | Tenascin (TN) (Cytotactin) (GMEM) (GP 150-225) (Glioma-associated-extracellular matrix antigen) (Hexabrachion) (JI) (Myotendinous antigen) (Neuronectin) (Tenascin-C) (TN-C) | TNC | bud outgrowth involved in lung branching [GO:0060447]; cell adhesion [GO:0007155]; cellular response to prostaglandin D stimulus [GO:0071799]; cellular response to retinoic acid [GO:0071300]; cellular response to vitamin D [GO:0071305]; mesenchymal-epithelial cell signaling involved in prostate gland development [GO:0060739]; morphogenesis of an epithelium [GO:0002009]; negative regulation of cell adhesion [GO:0007162]; neuromuscular junction development [GO:0007528]; odontogenesis of dentin-containing tooth [GO:0042475]; osteoblast differentiation [GO:0001649]; peripheral nervous system axon regeneration [GO:0014012]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; prostate gland epithelium morphogenesis [GO:0060740]; regulation of cell adhesion [GO:0030155]; regulation of cell growth [GO:0001558]; regulation of cell migration [GO:0030334]; regulation of inflammatory response [GO:0050727]; response to ethanol [GO:0045471]; response to fibroblast growth factor [GO:0071774]; response to mechanical stimulus [GO:0009612]; response to wounding [GO:0009611] | basement membrane [GO:0005604]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; interstitial matrix [GO:0005614]; membrane [GO:0016020]; perisynaptic extracellular matrix [GO:0098966]; tenascin complex [GO:0090733] | extracellular matrix structural constituent [GO:0005201]; integrin binding [GO:0005178]; syndecan binding [GO:0045545] | 31353.381431092 | -0.118337141468886 | 0.52122655106851 | 0.878687782908117 |
| Q9Y3D7 | Q9Y3D7 | TIM16_HUMAN | Mitochondrial import inner membrane translocase subunit TIM16 (Mitochondria-associated granulocyte macrophage CSF-signaling molecule) (Presequence translocated-associated motor subunit PAM16) | PAM16 | intracellular protein transport [GO:0006886]; negative regulation of ATP-dependent activity [GO:0032780]; ossification [GO:0001503]; protein import into mitochondrial matrix [GO:0030150] | mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; PAM complex, Tim23 associated import motor [GO:0001405]; protein-containing complex [GO:0032991]; TIM23 mitochondrial import inner membrane translocase complex [GO:0005744] | 11310.3684021519 | -0.173347206645135 | 0.521532733027619 | 0.878942434662251 | |
| Q9UBY9 | Q9UBY9 | HSPB7_HUMAN | Heat shock protein beta-7 (HspB7) (Cardiovascular heat shock protein) (cvHsp) | HSPB7 | heart development [GO:0007507]; regulation of heart contraction [GO:0008016]; response to unfolded protein [GO:0006986] | actin cytoskeleton [GO:0015629]; aggresome [GO:0016235]; Cajal body [GO:0015030]; cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] | filamin binding [GO:0031005] | 24851.70072721485 | 0.205554116326621 | 0.521919484982461 | 0.879332679723647 |
| P15336 | P15336 | ATF2_HUMAN | Cyclic AMP-dependent transcription factor ATF-2 (cAMP-dependent transcription factor ATF-2) (Activating transcription factor 2) (Cyclic AMP-responsive element-binding protein 2) (CREB-2) (cAMP-responsive element-binding protein 2) (HB16) (cAMP response element-binding protein CRE-BP1) | ATF2 | abducens nucleus development [GO:0021742]; adipose tissue development [GO:0060612]; apoptotic process involved in development [GO:1902742]; BMP signaling pathway [GO:0030509]; brainstem development [GO:0003360]; cellular lipid metabolic process [GO:0044255]; cellular response to anisomycin [GO:0072740]; cellular response to leucine starvation [GO:1990253]; cellular response to oxidative stress [GO:0034599]; cellular response to virus [GO:0098586]; detection of cell density [GO:0060245]; DNA damage response [GO:0006974]; facial nucleus development [GO:0021754]; growth plate cartilage chondrocyte differentiation [GO:0003418]; growth plate cartilage chondrocyte proliferation [GO:0003419]; hematopoietic progenitor cell differentiation [GO:0002244]; hepatocyte apoptotic process [GO:0097284]; hypoglossal nucleus development [GO:0021743]; in utero embryonic development [GO:0001701]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; JNK cascade [GO:0007254]; liver development [GO:0001889]; mitotic intra-S DNA damage checkpoint signaling [GO:0031573]; motor neuron apoptotic process [GO:0097049]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of angiogenesis [GO:0016525]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neurofilament cytoskeleton organization [GO:0060052]; NK T cell differentiation [GO:0001865]; outflow tract morphogenesis [GO:0003151]; p38MAPK cascade [GO:0038066]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of cardiac muscle myoblast proliferation [GO:0110024]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of gene expression [GO:0010628]; positive regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902110]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transforming growth factor beta2 production [GO:0032915]; protein import into nucleus [GO:0006606]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]; response to organic cyclic compound [GO:0014070]; response to osmotic stress [GO:0006970]; transcription initiation-coupled chromatin remodeling [GO:0045815]; vacuole organization [GO:0007033]; white fat cell differentiation [GO:0050872] | chromatin [GO:0000785]; cytoplasm [GO:0005737]; H4 histone acetyltransferase complex [GO:1902562]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase II transcription regulator complex [GO:0090575]; site of double-strand break [GO:0035861] | cAMP response element binding [GO:0035497]; cAMP response element binding protein binding [GO:0008140]; cis-regulatory region sequence-specific DNA binding [GO:0000987]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; histone acetyltransferase activity [GO:0004402]; histone H2B acetyltransferase activity [GO:0044013]; histone H4 acetyltransferase activity [GO:0010485]; identical protein binding [GO:0042802]; leucine zipper domain binding [GO:0043522]; metal ion binding [GO:0046872]; promoter-specific chromatin binding [GO:1990841]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; sequence-specific double-stranded DNA binding [GO:1990837] | 3052.08744035363 | -0.819336828005974 | 0.522409262854443 | 0.879634735017317 |
| Q9HAB3 | Q9HAB3 | S52A2_HUMAN | Solute carrier family 52, riboflavin transporter, member 2 (Porcine endogenous retrovirus A receptor 1) (PERV-A receptor 1) (Protein GPR172A) (Riboflavin transporter 3) (hRFT3) | SLC52A2 | riboflavin metabolic process [GO:0006771]; riboflavin transport [GO:0032218] | plasma membrane [GO:0005886] | 4-hydroxybutyrate receptor activity [GO:0062124]; riboflavin transmembrane transporter activity [GO:0032217]; virus receptor activity [GO:0001618] | 20078.6174382225 | -0.188129228354831 | 0.522406989804228 | 0.879634735017317 |
| Q9Y277 | Q9Y277 | VDAC3_HUMAN | Voltage-dependent anion-selective channel protein 3 (VDAC-3) (hVDAC3) (Outer mitochondrial membrane protein porin 3) | VDAC3 | adenine transport [GO:0015853]; behavioral fear response [GO:0001662]; learning [GO:0007612]; neuron-neuron synaptic transmission [GO:0007270]; sperm mitochondrial sheath assembly [GO:0120317]; spermatogenesis [GO:0007283] | extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; pore complex [GO:0046930]; synapse [GO:0045202] | nucleotide binding [GO:0000166]; porin activity [GO:0015288]; voltage-gated monoatomic anion channel activity [GO:0008308] | 29144.0603343923 | 0.206902704466605 | 0.522837026087173 | 0.880093461024933 |
| P07237 | P07237 | PDIA1_HUMAN | Protein disulfide-isomerase (PDI) (EC 5.3.4.1) (Cellular thyroid hormone-binding protein) (Prolyl 4-hydroxylase subunit beta) (p55) | P4HB | cellular response to hypoxia [GO:0071456]; cellular response to interleukin-7 [GO:0098761]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; insulin processing [GO:0030070]; interleukin-12-mediated signaling pathway [GO:0035722]; interleukin-23-mediated signaling pathway [GO:0038155]; peptidyl-proline hydroxylation to 4-hydroxy-L-proline [GO:0018401]; positive regulation of cell adhesion [GO:0045785]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of viral entry into host cell [GO:0046598]; protein folding [GO:0006457]; protein folding in endoplasmic reticulum [GO:0034975]; regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902175]; response to endoplasmic reticulum stress [GO:0034976] | cytoskeleton [GO:0005856]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum chaperone complex [GO:0034663]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; melanosome [GO:0042470]; procollagen-proline 4-dioxygenase complex [GO:0016222]; protein-containing complex [GO:0032991] | actin binding [GO:0003779]; enzyme binding [GO:0019899]; integrin binding [GO:0005178]; procollagen-proline 4-dioxygenase activity [GO:0004656]; protein disulfide isomerase activity [GO:0003756]; protein heterodimerization activity [GO:0046982]; protein-disulfide reductase activity [GO:0015035]; RNA binding [GO:0003723]; thiol oxidase activity [GO:0016972] | 434491.50004630897 | 0.140025910636146 | 0.523165892420094 | 0.88038549048181 |
| Q15061 | Q15061 | WDR43_HUMAN | WD repeat-containing protein 43 (U3 small nucleolar RNA-associated protein 5 homolog) | WDR43 | maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; positive regulation of rRNA processing [GO:2000234]; positive regulation of transcription by RNA polymerase I [GO:0045943]; regulation of stem cell population maintenance [GO:2000036]; regulation of transcription elongation by RNA polymerase II [GO:0034243]; ribosomal small subunit biogenesis [GO:0042274] | chromatin [GO:0000785]; fibrillar center [GO:0001650]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; small-subunit processome [GO:0032040] | RNA binding [GO:0003723]; RNA polymerase II complex binding [GO:0000993]; transcription elongation factor activity [GO:0003711] | 9038.246028236226 | 0.0538715765851599 | 0.523384304222912 | 0.880491528422511 |
| Q9Y3U8 | Q9Y3U8 | RL36_HUMAN | Large ribosomal subunit protein eL36 (60S ribosomal protein L36) | RPL36 | cytoplasmic translation [GO:0002181]; translation [GO:0006412] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; cytosolic ribosome [GO:0022626]; membrane [GO:0016020]; nucleolus [GO:0005730]; synapse [GO:0045202] | RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735] | 869399.3400568925 | 0.169305796026587 | 0.523578118088475 | 0.880556134487771 |
| Q4KMP7 | Q4KMP7 | TB10B_HUMAN | TBC1 domain family member 10B (Rab27A-GAP-beta) | TBC1D10B | regulation of GTPase activity [GO:0043087]; retrograde transport, endosome to Golgi [GO:0042147] | cytosol [GO:0005829]; plasma membrane [GO:0005886] | GTPase activator activity [GO:0005096] | 8564.295249925206 | 0.129864942016252 | 0.523759552166899 | 0.880599888005238 |
| Q53GQ0 | Q53GQ0 | DHB12_HUMAN | Very-long-chain 3-oxoacyl-CoA reductase (EC 1.1.1.330) (17-beta-hydroxysteroid dehydrogenase 12) (17-beta-HSD 12) (3-ketoacyl-CoA reductase) (KAR) (Estradiol 17-beta-dehydrogenase 12) (EC 1.1.1.62) (Short chain dehydrogenase/reductase family 12C member 1) | HSD17B12 | estrogen biosynthetic process [GO:0006703]; extracellular matrix organization [GO:0030198]; fatty acid elongation, saturated fatty acid [GO:0019367]; long-chain fatty-acyl-CoA biosynthetic process [GO:0035338]; positive regulation of cell-substrate adhesion [GO:0010811] | endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular matrix [GO:0031012]; fatty acid elongase complex [GO:0009923] | collagen binding [GO:0005518]; estradiol 17-beta-dehydrogenase [NAD(P)] activity [GO:0004303]; fibronectin binding [GO:0001968]; heparin binding [GO:0008201]; oxidoreductase activity [GO:0016491]; very-long-chain 3-oxoacyl-CoA reductase activity [GO:0141040] | 82405.3651369774 | -0.0727539179999367 | 0.524039708116621 | 0.880809547964633 |
| P16035 | P16035 | TIMP2_HUMAN | Metalloproteinase inhibitor 2 (CSC-21K) (Tissue inhibitor of metalloproteinases 2) (TIMP-2) | TIMP2 | negative regulation of membrane protein ectodomain proteolysis [GO:0051045]; negative regulation of metallopeptidase activity [GO:1905049]; response to cytokine [GO:0034097]; response to hormone [GO:0009725] | collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724] | metalloendopeptidase inhibitor activity [GO:0008191]; molecular function inhibitor activity [GO:0140678]; peptidase inhibitor activity [GO:0030414]; protease binding [GO:0002020]; zinc ion binding [GO:0008270] | 11834.865138773599 | 0.144086105611094 | 0.52497583177996 | 0.8821213116445 |
| Q12906 | Q12906 | ILF3_HUMAN | Interleukin enhancer-binding factor 3 (Double-stranded RNA-binding protein 76) (DRBP76) (M-phase phosphoprotein 4) (MPP4) (Nuclear factor associated with dsRNA) (NFAR) (Nuclear factor of activated T-cells 90 kDa) (NF-AT-90) (Translational control protein 80) (TCP80) | ILF3 | defense response to virus [GO:0051607]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of translation [GO:0017148]; negative regulation of viral genome replication [GO:0045071]; positive regulation of DNA-templated transcription [GO:0045893]; protein phosphorylation [GO:0006468] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; precatalytic spliceosome [GO:0071011]; ribonucleoprotein complex [GO:1990904] | DNA binding [GO:0003677]; double-stranded RNA binding [GO:0003725]; mRNA 3'-UTR AU-rich region binding [GO:0035925]; RNA binding [GO:0003723]; single-stranded RNA binding [GO:0003727]; virus receptor activity [GO:0001618] | 79283.53841916949 | -0.0765016867341497 | 0.526505818193672 | 0.884429874261887 |
| Q96JB2 | Q96JB2 | COG3_HUMAN | Conserved oligomeric Golgi complex subunit 3 (COG complex subunit 3) (Component of oligomeric Golgi complex 3) (Vesicle-docking protein SEC34 homolog) (p94) | COG3 | autophagy [GO:0006914]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; glycosylation [GO:0070085]; Golgi organization [GO:0007030]; intra-Golgi vesicle-mediated transport [GO:0006891]; intracellular protein transport [GO:0006886]; protein glycosylation [GO:0006486]; protein localization to organelle [GO:0033365]; protein stabilization [GO:0050821]; retrograde transport, vesicle recycling within Golgi [GO:0000301]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890] | cis-Golgi network [GO:0005801]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi membrane [GO:0000139]; Golgi transport complex [GO:0017119]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588] | 4955.958696451446 | -0.247795167722434 | 0.5269246695951 | 0.884871125644883 | |
| Q8NE86 | Q8NE86 | MCU_HUMAN | Calcium uniporter protein, mitochondrial (HsMCU) (Coiled-coil domain-containing protein 109A) | MCU | calcium import into the mitochondrion [GO:0036444]; calcium-mediated signaling [GO:0019722]; glucose homeostasis [GO:0042593]; mitochondrial calcium ion homeostasis [GO:0051560]; mitochondrial calcium ion transmembrane transport [GO:0006851]; positive regulation of insulin secretion [GO:0032024]; positive regulation of mitochondrial calcium ion concentration [GO:0051561]; positive regulation of mitochondrial fission [GO:0090141]; positive regulation of neutrophil chemotaxis [GO:0090023]; protein complex oligomerization [GO:0051259] | calcium channel complex [GO:0034704]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; uniplex complex [GO:1990246] | calcium channel activity [GO:0005262]; identical protein binding [GO:0042802]; uniporter activity [GO:0015292] | 11565.0614357783 | -0.168665304455024 | 0.527432089581286 | 0.884992984312843 |
| Q5VTR2 | Q5VTR2 | BRE1A_HUMAN | E3 ubiquitin-protein ligase BRE1A (BRE1-A) (hBRE1) (EC 2.3.2.27) (RING finger protein 20) (RING-type E3 ubiquitin transferase BRE1A) | RNF20 | negative regulation of cell migration [GO:0030336]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein polyubiquitination [GO:0000209]; regulation of DNA-templated transcription [GO:0006355]; ubiquitin-dependent protein catabolic process [GO:0006511] | HULC complex [GO:0033503]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ubiquitin ligase complex [GO:0000151] | chromatin binding [GO:0003682]; histone binding [GO:0042393]; histone H2B C-terminal K residue ubiquitin ligase activity [GO:0140850]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; transcription coactivator activity [GO:0003713]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842] | 4941.2779039424495 | -0.178897180700511 | 0.527451329378219 | 0.884992984312843 |
| Q86V81 | Q86V81 | THOC4_HUMAN | THO complex subunit 4 (Tho4) (Ally of AML-1 and LEF-1) (Aly/REF export factor) (Transcriptional coactivator Aly/REF) (bZIP-enhancing factor BEF) | ALYREF | mRNA export from nucleus [GO:0006406]; mRNA processing [GO:0006397]; osteoblast differentiation [GO:0001649]; RNA export from nucleus [GO:0006405]; RNA splicing [GO:0008380] | catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription export complex [GO:0000346] | C5-methylcytidine-containing RNA reader activity [GO:0062153]; mRNA binding [GO:0003729]; RNA binding [GO:0003723] | 119021.7696636885 | 0.270067258971937 | 0.52821992774716 | 0.885471630359589 |
| P23528 | P23528 | COF1_HUMAN | Cofilin-1 (18 kDa phosphoprotein) (p18) (Cofilin, non-muscle isoform) | CFL1 | actin cytoskeleton organization [GO:0030036]; actin filament depolymerization [GO:0030042]; actin filament fragmentation [GO:0030043]; actin filament severing [GO:0051014]; cytoskeleton organization [GO:0007010]; establishment of spindle localization [GO:0051293]; mitotic cytokinesis [GO:0000281]; negative regulation of apoptotic process [GO:0043066]; positive regulation by host of viral process [GO:0044794]; positive regulation of embryonic development [GO:0040019]; regulation of cell morphogenesis [GO:0022604]; regulation of dendritic spine morphogenesis [GO:0061001]; response to virus [GO:0009615]; Rho protein signal transduction [GO:0007266] | actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; growth cone [GO:0030426]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane [GO:0016020]; nuclear matrix [GO:0016363]; nucleus [GO:0005634]; ruffle membrane [GO:0032587]; vesicle [GO:0031982] | actin filament binding [GO:0051015] | 454281.4453686305 | -0.113434704475583 | 0.529510424666695 | 0.886457028910691 |
| Q86YP4 | Q86YP4 | P66A_HUMAN | Transcriptional repressor p66-alpha (Hp66alpha) (GATA zinc finger domain-containing protein 2A) | GATAD2A | chromatin remodeling [GO:0006338]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of cell fate specification [GO:0042659]; regulation of stem cell differentiation [GO:2000736] | nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; NuRD complex [GO:0016581] | metal ion binding [GO:0046872]; protein-macromolecule adaptor activity [GO:0030674]; sequence-specific DNA binding [GO:0043565] | 4284.4486696638505 | 0.353584999435001 | 0.529319451297257 | 0.886457028910691 |
| P28331 | P28331 | NDUS1_HUMAN | NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial (EC 7.1.1.2) (Complex I-75kD) (CI-75kD) | NDUFS1 | aerobic respiration [GO:0009060]; apoptotic mitochondrial changes [GO:0008637]; ATP metabolic process [GO:0046034]; cellular respiration [GO:0045333]; mitochondrial electron transport, NADH to ubiquinone [GO:0006120]; mitochondrial respiratory chain complex I assembly [GO:0032981]; proton motive force-driven mitochondrial ATP synthesis [GO:0042776]; reactive oxygen species metabolic process [GO:0072593]; regulation of mitochondrial membrane potential [GO:0051881] | mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrial respiratory chain complex I [GO:0005747]; mitochondrion [GO:0005739] | 2 iron, 2 sulfur cluster binding [GO:0051537]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; NADH dehydrogenase (ubiquinone) activity [GO:0008137] | 21123.0393473648 | -0.148579691895338 | 0.529226572457463 | 0.886457028910691 |
| Q9Y343 | Q9Y343 | SNX24_HUMAN | Sorting nexin-24 | SNX24 | protein transport [GO:0015031] | cytoplasmic vesicle membrane [GO:0030659] | phosphatidylinositol phosphate binding [GO:1901981]; phosphatidylinositol-3-phosphate binding [GO:0032266]; phosphatidylinositol-4-phosphate binding [GO:0070273]; phosphatidylinositol-5-phosphate binding [GO:0010314] | 8307.886985104004 | -0.209184660936061 | 0.529590018154375 | 0.886457028910691 |
| Q712K3 | Q712K3 | UB2R2_HUMAN | Ubiquitin-conjugating enzyme E2 R2 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme R2) (Ubiquitin carrier protein R2) (Ubiquitin-conjugating enzyme E2-CDC34B) (Ubiquitin-protein ligase R2) | UBE2R2 | protein K48-linked ubiquitination [GO:0070936]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; ubiquitin-dependent protein catabolic process [GO:0006511] | cytosol [GO:0005829] | ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin-protein transferase activity [GO:0004842] | 20466.2362040027 | 0.139661406709921 | 0.529409299985123 | 0.886457028910691 |
| Q9BVC4 | Q9BVC4 | LST8_HUMAN | Target of rapamycin complex subunit LST8 (TORC subunit LST8) (G protein beta subunit-like) (Gable) (Protein GbetaL) (Mammalian lethal with SEC13 protein 8) (mLST8) | MLST8 | cellular response to hypoxia [GO:0071456]; cellular response to nutrient levels [GO:0031669]; cellular response to osmotic stress [GO:0071470]; cytoskeleton organization [GO:0007010]; DNA damage response [GO:0006974]; negative regulation of apoptotic process [GO:0043066]; negative regulation of autophagy [GO:0010507]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell growth [GO:0030307]; positive regulation of glycolytic process [GO:0045821]; positive regulation of lipid biosynthetic process [GO:0046889]; positive regulation of pentose-phosphate shunt [GO:1905857]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of TOR signaling [GO:0032008]; regulation of actin cytoskeleton organization [GO:0032956]; TOR signaling [GO:0031929]; TORC1 signaling [GO:0038202] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; lysosomal membrane [GO:0005765]; nucleoplasm [GO:0005654]; TORC1 complex [GO:0031931]; TORC2 complex [GO:0031932] | protein serine/threonine kinase activator activity [GO:0043539] | 4313.44651557134 | -0.310808234137139 | 0.5301139892041 | 0.886857517338357 |
| O60784 | O60784 | TOM1_HUMAN | Target of Myb1 membrane trafficking protein (Target of Myb protein 1) | TOM1 | autophagosome-lysosome fusion [GO:0061909]; endocytosis [GO:0006897]; endosomal transport [GO:0016197]; positive regulation of autophagosome maturation [GO:1901098]; protein transport [GO:0015031]; regulation of endosome organization [GO:1904978]; signal transduction [GO:0007165]; substrate localization to autophagosome [GO:0061753] | azurophil granule membrane [GO:0035577]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579] | clathrin binding [GO:0030276]; clathrin heavy chain binding [GO:0032050]; myosin VI binding [GO:0070853]; phosphatidylinositol-5-phosphate binding [GO:0010314]; polyubiquitin modification-dependent protein binding [GO:0031593]; ubiquitin binding [GO:0043130] | 31207.45999675795 | -0.124513816817663 | 0.530298847289508 | 0.886857517338357 |
| Q9UBQ0 | Q9UBQ0 | VPS29_HUMAN | Vacuolar protein sorting-associated protein 29 (hVPS29) (PEP11 homolog) (Vesicle protein sorting 29) | VPS29 | endocytic recycling [GO:0032456]; intracellular protein transport [GO:0006886]; retrograde transport, endosome to Golgi [GO:0042147] | cytosol [GO:0005829]; early endosome [GO:0005769]; endosome [GO:0005768]; endosome membrane [GO:0010008]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; retromer complex [GO:0030904]; retromer, cargo-selective complex [GO:0030906] | metal ion binding [GO:0046872] | 32594.175379315 | -0.106054075182246 | 0.530274331789052 | 0.886857517338357 |
| P11441 | P11441 | UBL4A_HUMAN | Ubiquitin-like protein 4A (Ubiquitin-like protein GDX) | UBL4A | post-translational protein targeting to endoplasmic reticulum membrane [GO:0006620]; protein modification process [GO:0036211]; regulation of protein stability [GO:0031647]; tail-anchored membrane protein insertion into ER membrane [GO:0071816]; ubiquitin-dependent protein catabolic process [GO:0006511] | BAT3 complex [GO:0071818]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] | protein-folding chaperone binding [GO:0051087]; ubiquitin-like protein transferase activity [GO:0019787] | 13527.20671055415 | 0.211064843767895 | 0.530578309313971 | 0.887063057118016 |
| P08397 | P08397 | HEM3_HUMAN | Porphobilinogen deaminase (PBG-D) (EC 2.5.1.61) (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) | HMBS | heme A biosynthetic process [GO:0006784]; heme B biosynthetic process [GO:0006785]; heme biosynthetic process [GO:0006783]; heme O biosynthetic process [GO:0048034]; protoporphyrinogen IX biosynthetic process [GO:0006782] | cytoplasm [GO:0005737]; cytosol [GO:0005829] | hydroxymethylbilane synthase activity [GO:0004418] | 5543.875472862435 | 0.171123420127016 | 0.531049107535874 | 0.88758827235937 |
| P63261 | P63261 | ACTG_HUMAN | Actin, cytoplasmic 2 (EC 3.6.4.-) (Gamma-actin) [Cleaved into: Actin, cytoplasmic 2, N-terminally processed] | ACTG1 | angiogenesis [GO:0001525]; axonogenesis [GO:0007409]; cell motility [GO:0048870]; cellular response to type II interferon [GO:0071346]; maintenance of blood-brain barrier [GO:0035633]; morphogenesis of a polarized epithelium [GO:0001738]; platelet aggregation [GO:0070527]; positive regulation of cell migration [GO:0030335]; positive regulation of gene expression [GO:0010628]; positive regulation of wound healing [GO:0090303]; protein localization to bicellular tight junction [GO:1902396]; regulation of focal adhesion assembly [GO:0051893]; regulation of stress fiber assembly [GO:0051492]; regulation of synaptic vesicle endocytosis [GO:1900242]; regulation of transepithelial transport [GO:0150111]; sarcomere organization [GO:0045214]; tight junction assembly [GO:0120192] | actin filament [GO:0005884]; apical junction complex [GO:0043296]; axon [GO:0030424]; basal body patch [GO:0120220]; blood microparticle [GO:0072562]; calyx of Held [GO:0044305]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dense body [GO:0097433]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filamentous actin [GO:0031941]; focal adhesion [GO:0005925]; membrane [GO:0016020]; myofibril [GO:0030016]; NuA4 histone acetyltransferase complex [GO:0035267]; nucleus [GO:0005634]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202] | ATP binding [GO:0005524]; hydrolase activity [GO:0016787]; identical protein binding [GO:0042802]; profilin binding [GO:0005522]; protein kinase binding [GO:0019901]; structural constituent of cytoskeleton [GO:0005200]; structural constituent of postsynaptic actin cytoskeleton [GO:0098973]; ubiquitin protein ligase binding [GO:0031625] | 107096.52776641451 | -0.139372264330222 | 0.531354133896018 | 0.887836190697386 |
| O43813 | O43813 | LANC1_HUMAN | Glutathione S-transferase LANCL1 (EC 2.5.1.18) (40 kDa erythrocyte membrane protein) (p40) (LanC-like protein 1) | LANCL1 | carbohydrate metabolic process [GO:0005975]; cellular detoxification [GO:1990748]; G protein-coupled receptor signaling pathway [GO:0007186]; peptide modification [GO:0031179] | cytoplasm [GO:0005737]; plasma membrane [GO:0005886] | G protein-coupled receptor activity [GO:0004930]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; low-density lipoprotein particle receptor binding [GO:0050750]; SH3 domain binding [GO:0017124]; zinc ion binding [GO:0008270] | 28322.0299007326 | -0.119559395804037 | 0.53328957092658 | 0.890091893131357 |
| O00217 | O00217 | NDUS8_HUMAN | NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (EC 7.1.1.2) (Complex I-23kD) (CI-23kD) (NADH-ubiquinone oxidoreductase 23 kDa subunit) (TYKY subunit) | NDUFS8 | aerobic respiration [GO:0009060]; mitochondrial electron transport, NADH to ubiquinone [GO:0006120]; mitochondrial respiratory chain complex I assembly [GO:0032981]; proton motive force-driven mitochondrial ATP synthesis [GO:0042776]; response to oxidative stress [GO:0006979] | mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial respiratory chain complex I [GO:0005747]; mitochondrion [GO:0005739] | 4 iron, 4 sulfur cluster binding [GO:0051539]; metal ion binding [GO:0046872]; NADH dehydrogenase (ubiquinone) activity [GO:0008137] | 30609.23075923845 | 0.212138905442285 | 0.533384364124025 | 0.890091893131357 |
| Q86WA9 | Q86WA9 | S2611_HUMAN | Sodium-independent sulfate anion transporter (Solute carrier family 26 member 11) | SLC26A11 | monoatomic ion transport [GO:0006811]; oxalate transport [GO:0019532]; sulfate transport [GO:0008272] | apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] | chloride channel activity [GO:0005254]; chloride:bicarbonate antiporter activity [GO:0140900]; monoatomic anion transmembrane transporter activity [GO:0008509]; secondary active sulfate transmembrane transporter activity [GO:0008271]; sulfate transmembrane transporter activity [GO:0015116] | 1603.687633163795 | 0.411621604140215 | 0.533489599201216 | 0.890091893131357 |
| Q96C57 | Q96C57 | CSTOS_HUMAN | Protein CUSTOS | CUSTOS | negative regulation of Wnt signaling pathway [GO:0030178]; Spemann organizer formation [GO:0060061]; Wnt signaling pathway [GO:0016055] | nuclear envelope [GO:0005635] | 5237.331772730206 | 0.151077518958524 | 0.53374190519464 | 0.890249621956468 | |
| Q32P44 | Q32P44 | EMAL3_HUMAN | Echinoderm microtubule-associated protein-like 3 (EMAP-3) | EML3 | cell division [GO:0051301]; microtubule cytoskeleton organization [GO:0000226]; mitotic metaphase chromosome alignment [GO:0007080]; regulation of mitotic spindle assembly [GO:1901673] | cytoplasm [GO:0005737]; microtubule cytoskeleton [GO:0015630]; midbody [GO:0030496]; mitotic spindle microtubule [GO:1990498]; nucleus [GO:0005634]; spindle [GO:0005819]; spindle microtubule [GO:0005876] | microtubule binding [GO:0008017]; protein self-association [GO:0043621] | 8663.0269551694 | -0.182860725049007 | 0.534094598700729 | 0.890314797363439 |
| P32969 | P32969 | RL9_HUMAN | Large ribosomal subunit protein uL6 (60S ribosomal protein L9) | RPL9; RPL9P7; RPL9P8; RPL9P9 | cytoplasmic translation [GO:0002181]; translation [GO:0006412] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; cytosolic ribosome [GO:0022626]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; ribosome [GO:0005840] | RNA binding [GO:0003723]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735] | 196549.0570609565 | 0.16003956175897 | 0.534822030277007 | 0.891265183396919 |
| O00273 | O00273 | DFFA_HUMAN | DNA fragmentation factor subunit alpha (DNA fragmentation factor 45 kDa subunit) (DFF-45) (Inhibitor of CAD) (ICAD) | DFFA | apoptotic DNA fragmentation [GO:0006309]; chaperone-mediated protein folding [GO:0061077]; negative regulation of apoptotic DNA fragmentation [GO:1902511]; negative regulation of deoxyribonuclease activity [GO:0032076]; negative regulation of execution phase of apoptosis [GO:1900118]; positive regulation of apoptotic process [GO:0043065]; thymocyte apoptotic process [GO:0070242] | chromatin [GO:0000785]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991] | deoxyribonuclease inhibitor activity [GO:0060703]; protein domain specific binding [GO:0019904]; protein folding chaperone [GO:0044183] | 13777.3318238255 | 0.113424972493489 | 0.535154961511671 | 0.891376392291762 |
| Q7Z3T8 | Q7Z3T8 | ZFY16_HUMAN | Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosome-associated FYVE domain protein) | ZFYVE16 | endosomal transport [GO:0016197]; protein targeting to lysosome [GO:0006622]; regulation of endocytosis [GO:0030100]; signal transduction [GO:0007165]; vesicle organization [GO:0016050] | cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; intracellular membrane-bounded organelle [GO:0043231] | 1-phosphatidylinositol binding [GO:0005545]; metal ion binding [GO:0046872]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547] | 9367.34718529583 | 0.165064202857829 | 0.535235694845748 | 0.891376392291762 |
| Q9H8Y5 | Q9H8Y5 | ANKZ1_HUMAN | tRNA endonuclease ANKZF1 (EC 3.1.-.-) (Ankyrin repeat and zinc finger domain-containing protein 1) (Zinc finger protein 744) | ANKZF1 | cellular response to hydrogen peroxide [GO:0070301]; ERAD pathway [GO:0036503]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; rescue of stalled ribosome [GO:0072344] | cytoplasm [GO:0005737]; membrane [GO:0016020] | catalytic activity, acting on a tRNA [GO:0140101]; metal ion binding [GO:0046872]; RNA endonuclease activity [GO:0004521] | 9138.62329686921 | 0.148821001979612 | 0.53716582441043 | 0.893029343653378 |
| Q6QNY1 | Q6QNY1 | BL1S2_HUMAN | Biogenesis of lysosome-related organelles complex 1 subunit 2 (BLOC-1 subunit 2) (Centrosome-associated protein) | BLOC1S2 | anterograde axonal transport [GO:0008089]; anterograde synaptic vesicle transport [GO:0048490]; endosomal transport [GO:0016197]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; lysosome localization [GO:0032418]; melanosome organization [GO:0032438]; microtubule nucleation [GO:0007020]; mitochondrial outer membrane permeabilization [GO:0097345]; neuron projection development [GO:0031175]; organelle transport along microtubule [GO:0072384]; platelet dense granule organization [GO:0060155]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of endosome size [GO:0051036]; regulation of lysosome size [GO:0062196] | axon cytoplasm [GO:1904115]; BLOC-1 complex [GO:0031083]; BORC complex [GO:0099078]; centrosome [GO:0005813]; cytoplasmic side of lysosomal membrane [GO:0098574]; cytosol [GO:0005829]; gamma-tubulin complex [GO:0000930]; mitochondrion [GO:0005739]; nucleus [GO:0005634] | gamma-tubulin binding [GO:0043015] | 22794.4281434706 | 0.137388175764571 | 0.537205411306835 | 0.893029343653378 |
| O15357 | O15357 | SHIP2_HUMAN | Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 (EC 3.1.3.86) (Inositol polyphosphate phosphatase-like protein 1) (INPPL-1) (Protein 51C) (SH2 domain-containing inositol 5'-phosphatase 2) (SH2 domain-containing inositol phosphatase 2) (SHIP-2) | INPPL1 | actin filament organization [GO:0007015]; apoptotic process [GO:0006915]; cell adhesion [GO:0007155]; endochondral ossification [GO:0001958]; endocytosis [GO:0006897]; ERK1 and ERK2 cascade [GO:0070371]; establishment of mitotic spindle orientation [GO:0000132]; gene expression [GO:0010467]; glucose metabolic process [GO:0006006]; immune system process [GO:0002376]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of insulin-like growth factor receptor signaling pathway [GO:0043569]; phosphatidylinositol 3-kinase/protein kinase B signal transduction [GO:0043491]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; post-embryonic development [GO:0009791]; regulation of actin filament organization [GO:0110053]; regulation of immune response [GO:0050776]; regulation of protein localization [GO:0032880]; response to insulin [GO:0032868]; ruffle assembly [GO:0097178] | basal plasma membrane [GO:0009925]; cytosol [GO:0005829]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; lamellipodium [GO:0030027]; nuclear speck [GO:0016607]; nucleus [GO:0005634]; spindle pole [GO:0000922] | actin binding [GO:0003779]; inositol-polyphosphate 5-phosphatase activity [GO:0004445]; phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity [GO:0034485]; SH2 domain binding [GO:0042169]; SH3 domain binding [GO:0017124] | 10947.78186646025 | -0.126852934075814 | 0.536822510752368 | 0.893029343653378 |
| Q13613 | Q13613 | MTMR1_HUMAN | Myotubularin-related protein 1 (Phosphatidylinositol-3,5-bisphosphate 3-phosphatase) (EC 3.1.3.95) (Phosphatidylinositol-3-phosphate phosphatase) (EC 3.1.3.64) | MTMR1 | phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; regulation of phosphatidylinositol dephosphorylation [GO:0060304] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886] | phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity [GO:0052629]; phosphatidylinositol-3-phosphate phosphatase activity [GO:0004438]; protein homodimerization activity [GO:0042803] | 8776.05312646563 | 0.185812185643802 | 0.537159218658812 | 0.893029343653378 |
| P55786 | P55786 | PSA_HUMAN | Puromycin-sensitive aminopeptidase (PSA) (EC 3.4.11.14) (Cytosol alanyl aminopeptidase) (AAP-S) | NPEPPS | cellular response to hypoxia [GO:0071456]; peptide catabolic process [GO:0043171]; positive regulation of protein targeting to mitochondrion [GO:1903955]; protein polyubiquitination [GO:0000209]; proteolysis [GO:0006508] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; nucleus [GO:0005634] | aminopeptidase activity [GO:0004177]; metalloaminopeptidase activity [GO:0070006]; peptide binding [GO:0042277]; zinc ion binding [GO:0008270] | 61435.4122421832 | 0.102333179392302 | 0.536745965360911 | 0.893029343653378 |
| Q2TAY7 | Q2TAY7 | SMU1_HUMAN | WD40 repeat-containing protein SMU1 (Smu-1 suppressor of mec-8 and unc-52 protein homolog) [Cleaved into: WD40 repeat-containing protein SMU1, N-terminally processed] | SMU1 | mRNA splicing, via spliceosome [GO:0000398]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA splicing [GO:0008380] | cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; precatalytic spliceosome [GO:0071011]; U2-type precatalytic spliceosome [GO:0071005] | 12596.624532162401 | -0.108870922106785 | 0.537299158580015 | 0.893029343653378 | |
| Q8N9N2 | Q8N9N2 | ASCC1_HUMAN | Activating signal cointegrator 1 complex subunit 1 (ASC-1 complex subunit p50) (Trip4 complex subunit p50) | ASCC1 | DNA dealkylation involved in DNA repair [GO:0006307]; DNA duplex unwinding [GO:0032508]; regulation of DNA-templated transcription [GO:0006355] | DNA repair complex [GO:1990391]; neuromuscular junction [GO:0031594]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription regulator complex [GO:0005667] | RNA binding [GO:0003723] | 10281.6396870884 | 0.172078100575166 | 0.539476988957634 | 0.895860673925543 |
| P98179 | P98179 | RBM3_HUMAN | RNA-binding protein 3 (RNA-binding motif protein 3) (RNPL) | RBM3 | positive regulation of mRNA splicing, via spliceosome [GO:0048026]; positive regulation of translation [GO:0045727]; regulation of translation [GO:0006417]; RNA processing [GO:0006396] | cytoplasm [GO:0005737]; dendrite [GO:0030425]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spliceosomal complex [GO:0005681] | ribosomal large subunit binding [GO:0043023]; RNA binding [GO:0003723] | 108399.8805730185 | 0.196655388044358 | 0.539287099237167 | 0.895860673925543 |
| Q9BWH6 | Q9BWH6 | RPAP1_HUMAN | RNA polymerase II-associated protein 1 | RPAP1 | transcription by RNA polymerase II [GO:0006366] | DNA-directed RNA polymerase complex [GO:0000428]; nucleus [GO:0005634] | DNA binding [GO:0003677]; nucleotidyltransferase activity [GO:0016779] | 1180.726480285185 | -0.338547683343967 | 0.539384201340186 | 0.895860673925543 |
| Q0VDF9 | Q0VDF9 | HSP7E_HUMAN | Heat shock 70 kDa protein 14 (HSP70-like protein 1) (Heat shock protein HSP60) (Heat shock protein family A member 14) | HSPA14 | 'de novo' cotranslational protein folding [GO:0051083]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein refolding [GO:0042026] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ribosome [GO:0005840] | ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-dependent protein folding chaperone [GO:0140662]; heat shock protein binding [GO:0031072]; protein folding chaperone [GO:0044183] | 11301.14488824705 | 0.257954588387098 | 0.539805832905889 | 0.896144110531722 |
| Q8IW45 | Q8IW45 | NNRD_HUMAN | ATP-dependent (S)-NAD(P)H-hydrate dehydratase (EC 4.2.1.93) (ATP-dependent NAD(P)HX dehydratase) (Carbohydrate kinase domain-containing protein) (NAD(P)HX dehydratase) | NAXD | metabolite repair [GO:0110051]; NAD biosynthesis via nicotinamide riboside salvage pathway [GO:0034356] | mitochondrial matrix [GO:0005759] | ADP-dependent NAD(P)H-hydrate dehydratase activity [GO:0052855]; ATP binding [GO:0005524]; ATP-dependent NAD(P)H-hydrate dehydratase activity [GO:0047453]; NADHX epimerase activity [GO:0052856]; NADPHX epimerase activity [GO:0052857] | 7487.30149792899 | 0.181347077693116 | 0.54110016800391 | 0.897766779475887 |
| P13726 | P13726 | TF_HUMAN | Tissue factor (TF) (Coagulation factor III) (Thromboplastin) (CD antigen CD142) | F3 | activation of blood coagulation via clotting cascade [GO:0002543]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of plasma proteins involved in acute inflammatory response [GO:0002541]; blood coagulation [GO:0007596]; cytokine-mediated signaling pathway [GO:0019221]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell migration [GO:0030335]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of platelet-derived growth factor receptor signaling pathway [GO:0010641]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of TOR signaling [GO:0032008]; protein processing [GO:0016485] | cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886]; serine-type peptidase complex [GO:1905286] | cytokine receptor activity [GO:0004896]; phospholipid binding [GO:0005543]; protease binding [GO:0002020] | 26105.54827689075 | 0.182687420902267 | 0.541740658731318 | 0.898566326806689 |
| P49768 | P49768 | PSN1_HUMAN | Presenilin-1 (PS-1) (EC 3.4.23.-) (Protein S182) [Cleaved into: Presenilin-1 NTF subunit; Presenilin-1 CTF subunit; Presenilin-1 CTF12 (PS1-CTF12)] | PSEN1 | amyloid precursor protein catabolic process [GO:0042987]; amyloid precursor protein metabolic process [GO:0042982]; amyloid-beta formation [GO:0034205]; apoptotic signaling pathway [GO:0097190]; astrocyte activation [GO:0048143]; astrocyte activation involved in immune response [GO:0002265]; autophagosome assembly [GO:0000045]; blood vessel development [GO:0001568]; brain morphogenesis [GO:0048854]; Cajal-Retzius cell differentiation [GO:0021870]; cell fate specification [GO:0001708]; cell-cell adhesion [GO:0098609]; cellular response to amyloid-beta [GO:1904646]; cerebellum development [GO:0021549]; cerebral cortex cell migration [GO:0021795]; choline transport [GO:0015871]; DNA damage response [GO:0006974]; dorsal/ventral neural tube patterning [GO:0021904]; embryonic limb morphogenesis [GO:0030326]; endoplasmic reticulum calcium ion homeostasis [GO:0032469]; epithelial cell proliferation [GO:0050673]; heart looping [GO:0001947]; hematopoietic progenitor cell differentiation [GO:0002244]; intracellular signal transduction [GO:0035556]; L-glutamate import across plasma membrane [GO:0098712]; learning or memory [GO:0007611]; locomotion [GO:0040011]; membrane protein ectodomain proteolysis [GO:0006509]; memory [GO:0007613]; mitochondrial transport [GO:0006839]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of apoptotic process [GO:0043066]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of axonogenesis [GO:0050771]; negative regulation of core promoter binding [GO:1904797]; negative regulation of gene expression [GO:0010629]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of ubiquitin-dependent protein catabolic process [GO:2000059]; neural retina development [GO:0003407]; neuron apoptotic process [GO:0051402]; neuron cellular homeostasis [GO:0070050]; neuron development [GO:0048666]; neuron migration [GO:0001764]; neuron projection maintenance [GO:1990535]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; positive regulation of amyloid fibril formation [GO:1905908]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of coagulation [GO:0050820]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of gene expression [GO:0010628]; positive regulation of glycolytic process [GO:0045821]; positive regulation of L-glutamate import across plasma membrane [GO:0002038]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor recycling [GO:0001921]; positive regulation of tumor necrosis factor production [GO:0032760]; post-embryonic development [GO:0009791]; protein catabolic process at postsynapse [GO:0140249]; protein glycosylation [GO:0006486]; protein processing [GO:0016485]; protein transport [GO:0015031]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of gene expression [GO:0010468]; regulation of neuron projection development [GO:0010975]; regulation of phosphorylation [GO:0042325]; regulation of postsynapse organization [GO:0099175]; regulation of resting membrane potential [GO:0060075]; regulation of synaptic plasticity [GO:0048167]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of synaptic vesicle cycle [GO:0098693]; response to oxidative stress [GO:0006979]; sequestering of calcium ion [GO:0051208]; skeletal system morphogenesis [GO:0048705]; skin morphogenesis [GO:0043589]; smooth endoplasmic reticulum calcium ion homeostasis [GO:0051563]; somitogenesis [GO:0001756]; synapse organization [GO:0050808]; synaptic vesicle targeting [GO:0016080]; T cell activation involved in immune response [GO:0002286]; T cell receptor signaling pathway [GO:0050852]; thymus development [GO:0048538] | aggresome [GO:0016235]; azurophil granule membrane [GO:0035577]; cell cortex [GO:0005938]; cell junction [GO:0030054]; cell surface [GO:0009986]; centrosome [GO:0005813]; ciliary rootlet [GO:0035253]; dendrite [GO:0030425]; dendritic shaft [GO:0043198]; early endosome membrane [GO:0031901]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; gamma-secretase complex [GO:0070765]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; growth cone [GO:0030426]; kinetochore [GO:0000776]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nuclear membrane [GO:0031965]; nuclear outer membrane [GO:0005640]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; rough endoplasmic reticulum [GO:0005791]; sarcolemma [GO:0042383]; smooth endoplasmic reticulum [GO:0005790]; synaptic vesicle [GO:0008021] | aspartic endopeptidase activity, intramembrane cleaving [GO:0042500]; aspartic-type endopeptidase activity [GO:0004190]; ATPase binding [GO:0051117]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium channel activity [GO:0005262]; endopeptidase activity [GO:0004175]; growth factor receptor binding [GO:0070851]; PDZ domain binding [GO:0030165] | 32404.84668130295 | 0.16450101691478 | 0.542408128530472 | 0.899078536573311 |
| Q9UJX5 | Q9UJX5 | APC4_HUMAN | Anaphase-promoting complex subunit 4 (APC4) (Cyclosome subunit 4) | ANAPC4 | anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell cycle [GO:0007049]; cell division [GO:0051301]; protein K11-linked ubiquitination [GO:0070979]; regulation of meiotic cell cycle [GO:0051445]; regulation of mitotic cell cycle [GO:0007346]; regulation of mitotic metaphase/anaphase transition [GO:0030071] | anaphase-promoting complex [GO:0005680]; cytosol [GO:0005829]; nuclear periphery [GO:0034399]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] | protein phosphatase binding [GO:0019903]; ubiquitin-protein transferase activity [GO:0004842] | 5215.075914543065 | -0.243959114224028 | 0.54483207088735 | 0.902069591388382 |
| Q8NFA0 | Q8NFA0 | UBP32_HUMAN | Ubiquitin carboxyl-terminal hydrolase 32 (EC 3.4.19.12) (Deubiquitinating enzyme 32) (Renal carcinoma antigen NY-REN-60) (Ubiquitin thioesterase 32) (Ubiquitin-specific-processing protease 32) | USP32 | positive regulation of TORC1 signaling [GO:1904263]; protein deubiquitination [GO:0016579]; proteolysis [GO:0006508] | cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139] | calcium ion binding [GO:0005509]; cysteine-type deubiquitinase activity [GO:0004843] | 2387.87123132581 | -0.175238530662118 | 0.544967209905124 | 0.902069591388382 |
| Q9H1H9 | Q9H1H9 | KI13A_HUMAN | Kinesin-like protein KIF13A (Kinesin-like protein RBKIN) | KIF13A | cell division [GO:0051301]; cytoskeleton-dependent intracellular transport [GO:0030705]; endosome to lysosome transport [GO:0008333]; Golgi to plasma membrane protein transport [GO:0043001]; intracellular protein transport [GO:0006886]; melanosome organization [GO:0032438]; microtubule-based movement [GO:0007018]; plus-end-directed vesicle transport along microtubule [GO:0072383]; regulation of cytokinesis [GO:0032465]; spindle assembly [GO:0051225]; vesicle cargo loading [GO:0035459] | centriole [GO:0005814]; centrosome [GO:0005813]; endosome membrane [GO:0010008]; Golgi membrane [GO:0000139]; kinesin complex [GO:0005871]; microtubule [GO:0005874]; midbody [GO:0030496]; nucleus [GO:0005634]; trans-Golgi network membrane [GO:0032588] | ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; microtubule binding [GO:0008017]; microtubule motor activity [GO:0003777] | 3941.30418597955 | -0.254825140434672 | 0.545922457942911 | 0.902859499913758 |
| Q5VY43 | Q5VY43 | PEAR1_HUMAN | Platelet endothelial aggregation receptor 1 (hPEAR1) (Multiple epidermal growth factor-like domains protein 12) (Multiple EGF-like domains protein 12) | PEAR1 | phosphatidylinositol 3-kinase/protein kinase B signal transduction [GO:0043491]; platelet aggregation [GO:0070527]; positive regulation of platelet activation [GO:0010572]; recognition of apoptotic cell [GO:0043654] | lamellipodium [GO:0030027]; membrane [GO:0016020]; phagocytic cup [GO:0001891] | signaling receptor activity [GO:0038023] | 7742.12105710227 | 0.451689098717147 | 0.54591614003683 | 0.902859499913758 |
| Q3LXA3 | Q3LXA3 | TKFC_HUMAN | Triokinase/FMN cyclase (Bifunctional ATP-dependent dihydroxyacetone kinase/FAD-AMP lyase (cyclizing)) [Includes: ATP-dependent dihydroxyacetone kinase (DHA kinase) (EC 2.7.1.28) (EC 2.7.1.29) (Glycerone kinase) (Triokinase) (Triose kinase); FAD-AMP lyase (cyclizing) (EC 4.6.1.15) (FAD-AMP lyase (cyclic FMN forming)) (FMN cyclase)] | TKFC | carbohydrate metabolic process [GO:0005975]; carbohydrate phosphorylation [GO:0046835]; fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate [GO:0061624]; glycerol catabolic process [GO:0019563]; negative regulation of MDA-5 signaling pathway [GO:0039534]; regulation of innate immune response [GO:0045088] | cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleus [GO:0005634] | ATP binding [GO:0005524]; FAD-AMP lyase (cyclizing) activity [GO:0034012]; glycerone kinase activity [GO:0004371]; metal ion binding [GO:0046872]; triokinase activity [GO:0050354] | 8125.738669431001 | -0.357673133769647 | 0.545871543155589 | 0.902859499913758 |
| Q9H0D6 | Q9H0D6 | XRN2_HUMAN | 5'-3' exoribonuclease 2 (EC 3.1.13.-) (DHM1-like protein) (DHP protein) | XRN2 | hippocampus development [GO:0021766]; mRNA processing [GO:0006397]; neuron differentiation [GO:0030182]; nuclear-transcribed mRNA catabolic process [GO:0000956]; retina development in camera-type eye [GO:0060041]; RNA catabolic process [GO:0006401]; RNA metabolic process [GO:0016070]; RNA processing [GO:0006396]; rRNA processing [GO:0006364]; spermatogenesis [GO:0007283]; termination of RNA polymerase II transcription [GO:0006369] | aggresome [GO:0016235]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] | 3'-5'-RNA exonuclease activity [GO:0000175]; 5'-3' exonuclease activity [GO:0008409]; 5'-3' RNA exonuclease activity [GO:0004534]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; nuclease activity [GO:0004518]; RNA binding [GO:0003723]; transcription termination site sequence-specific DNA binding [GO:0001147] | 8724.673812913668 | -0.157583753139923 | 0.546120427319234 | 0.902923356052167 |
| Q9H4I3 | Q9H4I3 | TRABD_HUMAN | TraB domain-containing protein (Protein TTG2) | TRABD | 5938.3750774398395 | -0.112702851757141 | 0.546716219814419 | 0.903644720381709 | |||
| Q13630 | Q13630 | FCL_HUMAN | GDP-L-fucose synthase (EC 1.1.1.271) (GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4-reductase) (Protein FX) (Red cell NADP(H)-binding protein) (Short-chain dehydrogenase/reductase family 4E member 1) | GFUS | 'de novo' GDP-L-fucose biosynthetic process [GO:0042351]; GDP-mannose metabolic process [GO:0019673]; leukocyte cell-cell adhesion [GO:0007159]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904906] | cytosol [GO:0005829]; extracellular exosome [GO:0070062] | electron transfer activity [GO:0009055]; GDP-4-dehydro-D-rhamnose reductase activity [GO:0042356]; GDP-L-fucose synthase activity [GO:0050577]; GDP-mannose 3,5-epimerase activity [GO:0047918]; identical protein binding [GO:0042802] | 74632.7175613877 | -0.151595335553379 | 0.547998664266047 | 0.905500271721032 |
| Q9HCU0 | Q9HCU0 | CD248_HUMAN | Endosialin (Tumor endothelial marker 1) (CD antigen CD248) | CD248 | anatomical structure regression [GO:0060033]; cell migration [GO:0016477]; endothelial cell apoptotic process [GO:0072577]; fibroblast migration [GO:0010761]; fibroblast proliferation [GO:0048144]; lymph node development [GO:0048535]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of fibroblast proliferation [GO:0048146] | cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012] | calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; extracellular matrix binding [GO:0050840]; extracellular matrix protein binding [GO:1990430] | 11850.88511499215 | 0.130258129799602 | 0.548215395989841 | 0.90553515976641 |
| Q99943 | Q99943 | PLCA_HUMAN | 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha (EC 2.3.1.51) (1-acylglycerol-3-phosphate O-acyltransferase 1) (1-AGP acyltransferase 1) (1-AGPAT 1) (Lysophosphatidic acid acyltransferase alpha) (LPAAT-alpha) (Protein G15) | AGPAT1 | CDP-diacylglycerol biosynthetic process [GO:0016024]; phosphatidic acid biosynthetic process [GO:0006654]; phospholipid metabolic process [GO:0006644]; positive regulation of cytokine production [GO:0001819]; positive regulation of cytokine-mediated signaling pathway [GO:0001961] | endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020] | 1-acylglycerol-3-phosphate O-acyltransferase activity [GO:0003841] | 20698.63830523395 | -0.0915014551005248 | 0.54907064660147 | 0.906478520875271 |
| Q9Y259 | Q9Y259 | CHKB_HUMAN | Choline/ethanolamine kinase (Choline kinase beta) (CK) (CKB) (EC 2.7.1.32) (Choline kinase-like protein) (Ethanolamine kinase) (EK) (EC 2.7.1.82) (Ethanolamine kinase beta) (EKB) (choline/ethanolamine kinase beta) (CKEKB) | CHKB | CDP-choline pathway [GO:0006657]; muscle organ development [GO:0007517]; phosphatidylethanolamine biosynthetic process [GO:0006646]; phosphorylation [GO:0016310] | cytoplasm [GO:0005737]; cytosol [GO:0005829] | ATP binding [GO:0005524]; choline kinase activity [GO:0004103]; ethanolamine kinase activity [GO:0004305] | 3997.884101667725 | 0.231472989004156 | 0.550137182562873 | 0.906706032124534 |
| Q96FJ2 | Q96FJ2 | DYL2_HUMAN | Dynein light chain 2, cytoplasmic (8 kDa dynein light chain b) (DLC8b) (Dynein light chain LC8-type 2) | DYNLL2 | microtubule-based process [GO:0007017] | 9+0 non-motile cilium [GO:0097731]; centrosome [GO:0005813]; ciliary tip [GO:0097542]; cilium [GO:0005929]; cytoplasmic dynein complex [GO:0005868]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; microtubule [GO:0005874]; myosin V complex [GO:0031475]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794] | dynein intermediate chain binding [GO:0045505] | 43094.2874672252 | 0.0890851839901732 | 0.549655487552826 | 0.906706032124534 |
| Q9HD26 | Q9HD26 | GOPC_HUMAN | Golgi-associated PDZ and coiled-coil motif-containing protein (CFTR-associated ligand) (Fused in glioblastoma) (PDZ protein interacting specifically with TC10) (PIST) | GOPC | apical protein localization [GO:0045176]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi to plasma membrane transport [GO:0006893]; negative regulation of anion channel activity [GO:0010360]; negative regulation of protein localization to cell surface [GO:2000009]; protein transport [GO:0015031] | cytoplasm [GO:0005737]; dendrite [GO:0030425]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; Golgi-associated vesicle membrane [GO:0030660]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; protein-containing complex [GO:0032991]; trans-Golgi network transport vesicle [GO:0030140] | identical protein binding [GO:0042802]; molecular sequestering activity [GO:0140313]; transmembrane transporter binding [GO:0044325] | 29483.54370405605 | 0.103700059655152 | 0.550329186503818 | 0.906706032124534 |
| O14807 | O14807 | RASM_HUMAN | Ras-related protein M-Ras (EC 3.6.5.2) (Ras-related protein R-Ras3) | MRAS | actin cytoskeleton organization [GO:0030036]; cellular response to leukemia inhibitory factor [GO:1990830]; Ras protein signal transduction [GO:0007265] | plasma membrane [GO:0005886] | G protein activity [GO:0003925]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTP-dependent protein binding [GO:0030742]; GTPase activity [GO:0003924] | 9235.37123820777 | 0.188172823198298 | 0.550488660520367 | 0.906706032124534 |
| Q9BTW9 | Q9BTW9 | TBCD_HUMAN | Tubulin-specific chaperone D (Beta-tubulin cofactor D) (tfcD) (SSD-1) (Tubulin-folding cofactor D) | TBCD | adherens junction assembly [GO:0034333]; bicellular tight junction assembly [GO:0070830]; cell morphogenesis involved in neuron differentiation [GO:0048667]; microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of microtubule polymerization [GO:0031115]; post-chaperonin tubulin folding pathway [GO:0007023]; protein folding [GO:0006457]; tubulin complex assembly [GO:0007021] | adherens junction [GO:0005912]; bicellular tight junction [GO:0005923]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; lateral plasma membrane [GO:0016328]; microtubule [GO:0005874] | beta-tubulin binding [GO:0048487]; GTPase activator activity [GO:0005096]; protein-folding chaperone binding [GO:0051087] | 8627.906124965115 | -0.165888706005676 | 0.550036771954631 | 0.906706032124534 |
| Q9UI30 | Q9UI30 | TR112_HUMAN | Multifunctional methyltransferase subunit TRM112-like protein (tRNA methyltransferase 112 homolog) | TRMT112 | peptidyl-glutamine methylation [GO:0018364]; positive regulation of rRNA processing [GO:2000234]; rRNA (guanine-N7)-methylation [GO:0070476]; rRNA methylation [GO:0031167]; transcription initiation-coupled chromatin remodeling [GO:0045815]; tRNA methylation [GO:0030488] | cytosol [GO:0005829]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; protein-containing complex [GO:0032991] | protein heterodimerization activity [GO:0046982]; protein methyltransferase activity [GO:0008276]; tRNA methyltransferase activator activity [GO:0141106] | 34386.33567660255 | -0.0634220814155202 | 0.550265887548842 | 0.906706032124534 |
| Q14D04 | Q14D04 | MELT_HUMAN | Ventricular zone-expressed PH domain-containing protein homolog 1 (Protein melted) | VEPH1 | negative regulation of SMAD protein signal transduction [GO:0060392]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; regulation of signal transduction [GO:0009966] | plasma membrane [GO:0005886] | phosphatidylinositol-5-phosphate binding [GO:0010314] | 1866.8084640382249 | -0.897681573089367 | 0.549719907171361 | 0.906706032124534 |
| Q14152 | Q14152 | EIF3A_HUMAN | Eukaryotic translation initiation factor 3 subunit A (eIF3a) (Eukaryotic translation initiation factor 3 subunit 10) (eIF-3-theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) | EIF3A | formation of cytoplasmic translation initiation complex [GO:0001732]; IRES-dependent viral translational initiation [GO:0075522]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; translation reinitiation [GO:0002188]; translational initiation [GO:0006413]; viral translational termination-reinitiation [GO:0075525] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; eukaryotic 43S preinitiation complex [GO:0016282]; eukaryotic 48S preinitiation complex [GO:0033290]; eukaryotic translation initiation factor 3 complex [GO:0005852]; eukaryotic translation initiation factor 3 complex, eIF3e [GO:0071540]; eukaryotic translation initiation factor 3 complex, eIF3m [GO:0071541]; membrane [GO:0016020]; microtubule [GO:0005874]; multi-eIF complex [GO:0043614]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; postsynaptic density [GO:0014069] | mRNA binding [GO:0003729]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]; translation initiation factor activity [GO:0003743] | 50040.19323440765 | -0.10201101994438 | 0.550696738663251 | 0.906785155845969 |
| P51692 | P51692 | STA5B_HUMAN | Signal transducer and activator of transcription 5B | STAT5B | activated T cell proliferation [GO:0050798]; B cell differentiation [GO:0030183]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to growth factor stimulus [GO:0071363]; cellular response to hormone stimulus [GO:0032870]; cytokine-mediated signaling pathway [GO:0019221]; defense response [GO:0006952]; development of secondary female sexual characteristics [GO:0046543]; development of secondary male sexual characteristics [GO:0046544]; erythrocyte differentiation [GO:0030218]; female pregnancy [GO:0007565]; gamma-delta T cell differentiation [GO:0042492]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; lactation [GO:0007595]; lipid storage [GO:0019915]; luteinization [GO:0001553]; mast cell migration [GO:0097531]; mitotic cell cycle [GO:0000278]; myeloid cell apoptotic process [GO:0033028]; natural killer cell differentiation [GO:0001779]; natural killer cell mediated cytotoxicity [GO:0042267]; natural killer cell proliferation [GO:0001787]; negative regulation of erythrocyte differentiation [GO:0045647]; negative regulation of myeloid cell apoptotic process [GO:0033033]; Peyer's patch development [GO:0048541]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of B cell differentiation [GO:0045579]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of gamma-delta T cell differentiation [GO:0045588]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of natural killer cell differentiation [GO:0032825]; positive regulation of natural killer cell mediated cytotoxicity [GO:0045954]; positive regulation of natural killer cell proliferation [GO:0032819]; positive regulation of transcription by RNA polymerase II [GO:0045944]; progesterone metabolic process [GO:0042448]; receptor signaling pathway via JAK-STAT [GO:0007259]; regulation of cell population proliferation [GO:0042127]; regulation of epithelial cell differentiation [GO:0030856]; regulation of multicellular organism growth [GO:0040014]; regulation of steroid metabolic process [GO:0019218]; regulation of transcription by RNA polymerase II [GO:0006357]; response to estradiol [GO:0032355]; response to interleukin-15 [GO:0070672]; response to interleukin-2 [GO:0070669]; response to interleukin-4 [GO:0070670]; response to peptide hormone [GO:0043434]; T cell differentiation in thymus [GO:0033077]; T cell homeostasis [GO:0043029]; taurine metabolic process [GO:0019530]; transcription by RNA polymerase II [GO:0006366] | chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase II transcription regulator complex [GO:0090575] | chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; nuclear glucocorticoid receptor binding [GO:0035259]; protein dimerization activity [GO:0046983]; protein homodimerization activity [GO:0042803]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] | 5619.47562470481 | 0.254323142288491 | 0.550881460359459 | 0.906825785705025 |
| Q9NUQ2 | Q9NUQ2 | PLCE_HUMAN | 1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon (EC 2.3.1.51) (1-acylglycerol-3-phosphate O-acyltransferase 5) (1-AGP acyltransferase 5) (1-AGPAT 5) (Lysophosphatidic acid acyltransferase epsilon) (LPAAT-epsilon) | AGPAT5 | acylglycerol metabolic process [GO:0006639]; CDP-diacylglycerol biosynthetic process [GO:0016024]; hematopoietic progenitor cell differentiation [GO:0002244]; phosphatidic acid biosynthetic process [GO:0006654]; phosphatidylinositol acyl-chain remodeling [GO:0036149]; phospholipid biosynthetic process [GO:0008654] | endomembrane system [GO:0012505]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; nuclear envelope [GO:0005635]; nucleolus [GO:0005730] | 1-acylglycerol-3-phosphate O-acyltransferase activity [GO:0003841]; acyltransferase activity [GO:0016746] | 3357.58447133968 | 0.26358481907359 | 0.551071216308733 | 0.906874676620762 |
| Q6P3X3 | Q6P3X3 | TTC27_HUMAN | Tetratricopeptide repeat protein 27 (TPR repeat protein 27) | TTC27 | 3786.83996558897 | -0.246900503618898 | 0.551474148500972 | 0.907010892715968 | |||
| Q16836 | Q16836 | HCDH_HUMAN | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial (HCDH) (EC 1.1.1.35) (Medium and short-chain L-3-hydroxyacyl-coenzyme A dehydrogenase) (Short-chain 3-hydroxyacyl-CoA dehydrogenase) | HADH | fatty acid beta-oxidation [GO:0006635]; negative regulation of insulin secretion [GO:0046676]; positive regulation of cold-induced thermogenesis [GO:0120162]; regulation of insulin secretion [GO:0050796]; response to activity [GO:0014823]; response to insulin [GO:0032868]; response to xenobiotic stimulus [GO:0009410] | cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654] | 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; identical protein binding [GO:0042802]; NAD+ binding [GO:0070403]; transferase activity [GO:0016740] | 9361.586115715269 | 0.103868329206425 | 0.551673679893264 | 0.90707576038167 |
| P27707 | P27707 | DCK_HUMAN | Deoxycytidine kinase (dCK) (EC 2.7.1.74) (Deoxyadenosine kinase) (EC 2.7.1.76) (Deoxyguanosine kinase) (EC 2.7.1.113) | DCK | dAMP salvage [GO:0106383]; nucleoside phosphate biosynthetic process [GO:1901293]; phosphorylation [GO:0016310]; pyrimidine nucleotide metabolic process [GO:0006220] | cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654] | ATP binding [GO:0005524]; cytidine kinase activity [GO:0043771]; deoxyadenosine kinase activity [GO:0004136]; deoxycytidine kinase activity [GO:0004137]; deoxyguanosine kinase activity [GO:0004138]; protein homodimerization activity [GO:0042803] | 7236.31772581588 | 0.127877755021703 | 0.553114390648951 | 0.908917093218375 |
| O14545 | O14545 | TRAD1_HUMAN | TRAF-type zinc finger domain-containing protein 1 (Protein FLN29) | TRAFD1 | negative regulation of innate immune response [GO:0045824] | mitochondrion [GO:0005739] | metal ion binding [GO:0046872] | 8909.385886975275 | 0.127362203262965 | 0.553721632221926 | 0.90965113603057 |
| Q96L58 | Q96L58 | B3GT6_HUMAN | Beta-1,3-galactosyltransferase 6 (Beta-1,3-GalTase 6) (Beta3Gal-T6) (Beta3GalT6) (EC 2.4.1.134) (GAG GalTII) (Galactosyltransferase II) (Galactosylxylosylprotein 3-beta-galactosyltransferase) (UDP-Gal:betaGal beta 1,3-galactosyltransferase polypeptide 6) | B3GALT6 | chondroitin sulfate biosynthetic process [GO:0030206]; glycosaminoglycan biosynthetic process [GO:0006024]; glycosaminoglycan metabolic process [GO:0030203]; heparan sulfate proteoglycan biosynthetic process [GO:0015012]; protein O-linked glycosylation [GO:0006493]; proteoglycan biosynthetic process [GO:0030166] | Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi medial cisterna [GO:0005797]; Golgi membrane [GO:0000139]; membrane [GO:0016020] | galactosylxylosylprotein 3-beta-galactosyltransferase activity [GO:0047220]; UDP-galactosyltransferase activity [GO:0035250] | 16132.02033802935 | -0.295572553963278 | 0.555006069722506 | 0.910968827070602 |
| P61962 | P61962 | DCAF7_HUMAN | DDB1- and CUL4-associated factor 7 (WD repeat-containing protein 68) (WD repeat-containing protein An11 homolog) | DCAF7 | protein ubiquitination [GO:0016567] | Cul4-RING E3 ubiquitin ligase complex [GO:0080008]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear body [GO:0016604]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991] | protein-macromolecule adaptor activity [GO:0030674] | 10499.3033450039 | 0.287942679964385 | 0.554850160978858 | 0.910968827070602 |
| Q9NYB0 | Q9NYB0 | TE2IP_HUMAN | Telomeric repeat-binding factor 2-interacting protein 1 (TERF2-interacting telomeric protein 1) (TRF2-interacting telomeric protein 1) (Dopamine receptor-interacting protein 5) (Repressor/activator protein 1 homolog) (RAP1 homolog) (hRap1) | TERF2IP | intracellular signal transduction [GO:0035556]; negative regulation of DNA recombination at telomere [GO:0048239]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of telomere maintenance [GO:0032205]; positive regulation of canonical NF-kappaB signal transduction [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of non-canonical NF-kappaB signal transduction [GO:1901224]; positive regulation of telomere maintenance [GO:0032206]; protection from non-homologous end joining at telomere [GO:0031848]; protein localization to chromosome, telomeric region [GO:0070198]; regulation of DNA-templated transcription [GO:0006355]; regulation of double-strand break repair via homologous recombination [GO:0010569]; regulation of telomere maintenance [GO:0032204]; telomere capping [GO:0016233]; telomere maintenance [GO:0000723]; telomere maintenance via telomerase [GO:0007004]; telomere maintenance via telomere lengthening [GO:0010833] | chromosome, telomeric region [GO:0000781]; cytoplasm [GO:0005737]; male germ cell nucleus [GO:0001673]; nuclear body [GO:0016604]; nuclear chromosome [GO:0000228]; nuclear telomere cap complex [GO:0000783]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; shelterin complex [GO:0070187] | G-rich strand telomeric DNA binding [GO:0098505]; phosphatase binding [GO:0019902]; telomeric DNA binding [GO:0042162] | 5506.7470520650295 | -0.317551821235399 | 0.554758079866327 | 0.910968827070602 |
| Q13200 | Q13200 | PSMD2_HUMAN | 26S proteasome non-ATPase regulatory subunit 2 (26S proteasome regulatory subunit RPN1) (26S proteasome regulatory subunit S2) (26S proteasome subunit p97) (Protein 55.11) (Tumor necrosis factor type 1 receptor-associated protein 2) | PSMD2 | proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of protein catabolic process [GO:0042176] | cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome accessory complex [GO:0022624]; proteasome complex [GO:0000502]; proteasome regulatory particle [GO:0005838]; proteasome regulatory particle, base subcomplex [GO:0008540]; proteasome storage granule [GO:0034515]; secretory granule lumen [GO:0034774] | enzyme regulator activity [GO:0030234] | 55093.35425069695 | 0.0978297987397522 | 0.555492420158135 | 0.911503056071819 |
| Q8IWZ8 | Q8IWZ8 | SUGP1_HUMAN | SURP and G-patch domain-containing protein 1 (RNA-binding protein RBP) (Splicing factor 4) | SUGP1 | mRNA processing [GO:0006397]; RNA splicing [GO:0008380] | nucleoplasm [GO:0005654]; spliceosomal complex [GO:0005681] | RNA binding [GO:0003723] | 6627.007063229605 | 0.144670677464611 | 0.555996545917637 | 0.912066134675544 |
| Q9Y6K8 | Q9Y6K8 | KAD5_HUMAN | Adenylate kinase isoenzyme 5 (AK 5) (EC 2.7.4.3) (EC 2.7.4.6) (ATP-AMP transphosphorylase 5) | AK5 | ADP biosynthetic process [GO:0006172]; ATP metabolic process [GO:0046034]; dADP biosynthetic process [GO:0006173]; phosphorylation [GO:0016310]; pyrimidine ribonucleotide biosynthetic process [GO:0009220] | centriolar satellite [GO:0034451]; cytoplasm [GO:0005737]; cytosol [GO:0005829] | adenylate kinase activity [GO:0004017]; ATP binding [GO:0005524]; cytidylate kinase activity [GO:0004127]; nucleoside diphosphate kinase activity [GO:0004550] | 15096.281935470652 | 0.168425828478355 | 0.556977324460831 | 0.912677003899066 |
| Q9NRG1 | Q9NRG1 | PRDC1_HUMAN | Phosphoribosyltransferase domain-containing protein 1 | PRTFDC1 | GMP salvage [GO:0032263]; hypoxanthine metabolic process [GO:0046100]; IMP salvage [GO:0032264]; purine ribonucleoside salvage [GO:0006166] | cytosol [GO:0005829] | magnesium ion binding [GO:0000287]; nucleotide binding [GO:0000166]; protein homodimerization activity [GO:0042803] | 5725.020317448405 | 0.0998860654987689 | 0.557013250879451 | 0.912677003899066 |
| P19404 | P19404 | NDUV2_HUMAN | NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (NDUFV2) (EC 7.1.1.2) (NADH-ubiquinone oxidoreductase 24 kDa subunit) | NDUFV2 | aerobic respiration [GO:0009060]; cardiac muscle tissue development [GO:0048738]; mitochondrial electron transport, NADH to ubiquinone [GO:0006120]; nervous system development [GO:0007399]; proton motive force-driven mitochondrial ATP synthesis [GO:0042776] | mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex I [GO:0005747]; mitochondrion [GO:0005739] | 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; NADH dehydrogenase (ubiquinone) activity [GO:0008137] | 18860.94644295975 | 0.186717994949504 | 0.558001146062231 | 0.914031365593698 |
| O00468 | O00468 | AGRIN_HUMAN | Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment (C90); Agrin C-terminal 22 kDa fragment (C22)] | AGRN | clustering of voltage-gated sodium channels [GO:0045162]; G protein-coupled acetylcholine receptor signaling pathway [GO:0007213]; neuromuscular junction development [GO:0007528]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of GTPase activity [GO:0043547]; positive regulation of synaptic assembly at neuromuscular junction [GO:0045887]; positive regulation of transcription by RNA polymerase II [GO:0045944]; receptor clustering [GO:0043113]; signal transduction [GO:0007165]; synapse organization [GO:0050808] | basement membrane [GO:0005604]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi lumen [GO:0005796]; lysosomal lumen [GO:0043202]; plasma membrane [GO:0005886]; synapse [GO:0045202] | calcium ion binding [GO:0005509]; chondroitin sulfate binding [GO:0035374]; dystroglycan binding [GO:0002162]; heparan sulfate proteoglycan binding [GO:0043395]; laminin binding [GO:0043236]; sialic acid binding [GO:0033691]; structural constituent of cytoskeleton [GO:0005200] | 8227.629354720364 | 0.130417850407962 | 0.558398611039659 | 0.914418072297893 |
| Q969N2 | Q969N2 | PIGT_HUMAN | GPI transamidase component PIG-T (Phosphatidylinositol-glycan biosynthesis class T protein) | PIGT | attachment of GPI anchor to protein [GO:0016255]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182] | cytoplasmic vesicle [GO:0031410]; endoplasmic reticulum membrane [GO:0005789]; GPI-anchor transamidase complex [GO:0042765]; membrane [GO:0016020] | 11202.0034751629 | 0.130196306600625 | 0.558900249925042 | 0.914720856262215 |
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| Q15149 | |||||||||
| Q99715 | |||||||||
| P02452 | |||||||||
| P02751 | |||||||||
| P98160 | |||||||||
| P08123 | |||||||||
| P02461 | |||||||||
| P07996 | |||||||||
| Q8WWI1 | |||||||||
| P05997 | |||||||||
| P20908 | |||||||||
| Q8WUJ3 | |||||||||
| P21333 | |||||||||
| O75369 | |||||||||
| Q15063 | |||||||||
| P02786 | |||||||||
| Q12884 | |||||||||
| P12814 | |||||||||
| Q9UDY2 | |||||||||
| Q14195 | |||||||||
| Q02952 | |||||||||
| Q9NZM1 | |||||||||
| P35579 | |||||||||
| P35354 | |||||||||
| P47895 | |||||||||
| Q09666 | |||||||||
| P11717 | |||||||||
| Q14112 | |||||||||
| Q13620 | |||||||||
| P43490 | |||||||||
| Q3SY69 | |||||||||
| P17812 | |||||||||
| P21980 | |||||||||
| Q16647 | |||||||||
| P01024 | |||||||||
| Q5SW79 | |||||||||
| P06396 | |||||||||
| P12111 | |||||||||
| P35221 | |||||||||
| P12429 | |||||||||
| P78559 | |||||||||
| Q76M96 | |||||||||
| Q16881 | |||||||||
| P07093 | |||||||||
| P27487 | |||||||||
| P15144 | |||||||||
| Q9H5V8 | |||||||||
| P08729 | |||||||||
| Q04828 | |||||||||
| O94925 | |||||||||
| P08473 | |||||||||
| Q8IVL5 | |||||||||
| P35442 | |||||||||
| O60716 | |||||||||
| P08253 | |||||||||
| Q16822 | |||||||||
| Q9UJ72 | |||||||||
| Q9Y617 | |||||||||
| Q8WX93 | |||||||||
| Q32MZ4 | |||||||||
| Q6P179 | |||||||||
| P48681 | |||||||||
| O95340 | |||||||||
| P21580 | |||||||||
| Q00341 | |||||||||
| P49748 | |||||||||
| O43854 | |||||||||
| P07942 | |||||||||
| Q96KC8 | |||||||||
| Q96PD2 | |||||||||
| Q13418 | |||||||||
| Q7Z7G0 | |||||||||
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