Selected Cell
Cell:
Value:
Note on data sheet
N1
N2
Combined_mean_clone_vs__mean_WT
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The sheets: "N1", and "N2" contain the normalised data (peak area/mg protein) and all of the data processing steps to get to relative level. | |||||||||
The data used for plotting, were: | |||||||||
Fig. S5: The mean of all of the data points pertaining to a single clone (e.g. all of the data points from KO4 in experiment N1) to the mean of the WT data in the same experiment. | |||||||||
The final data plotted in the figures are summarised in "Combined_mean_clone_vs__mean_WT" | |||||||||
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area ratio / mg protein | ||||||||||
Acylcarnitine chain-length: | C0 | C2:0 | C4:0 | C6:0 | C8:0 | C10:0 | C10:1 | C12:0 | C14:0 | C16:0 |
Group | Carnitine | Acetylcarnitine | Butyrylcarnitine | Hexanoylcarnitine | Octanoylcarnitine | Decanoylcarnitine | Decenoylcarnitine | Lauroylcarnitine | Myristoylcarnitine | Palmitoylcarnitine |
WT_1 | 0.5348955982179708 | 0.07320653113108985 | 0.016060123471301674 | 0.0011085094939801844 | 3.4492074850700374E-4 | 3.716787595011958E-4 | 1.7143200799453367E-5 | 0.0019242572087393235 | 0.004912412110515888 | 0.010173667198134608 |
WT_2 | 0.441237670573633 | 0.0586363573049271 | 0.01576956969987242 | 0.0012265956373572297 | 4.2644731165856624E-4 | 3.6283464323815304E-4 | 2.3769793238153103E-5 | 0.0018602421563608748 | 0.004601190556330498 | 0.008030529180577157 |
WT_3 | 0.4009133210089645 | 0.06427180117419941 | 0.01400695678608821 | 8.506124884515819E-4 | 3.787868567976989E-4 | 2.905661039693193E-4 | 1.4674399285714283E-5 | 0.0015349354928859058 | 0.004193152372464046 | 0.00788524112134228 |
WT_4 | 0.3784116728577457 | 0.05620975216860077 | 0.015179260209955582 | 7.921121413881177E-4 | 3.427846158967241E-4 | 2.3351935757912274E-4 | 1.72869993337035E-5 | 0.0016023829835147142 | 0.004169921262098834 | 0.006832359100544144 |
WT_5 | 0.4585508268873758 | 0.06038850260957335 | 0.010101733189567504 | 6.708047798772648E-4 | 2.443237737112799E-4 | 2.0442308305669202E-4 | 1.0911575774400935E-5 | 0.0011390234696843952 | 0.0031288884765575693 | 0.005594823351209819 |
KO4_1 | 0.3255523696758561 | 0.04550260243722174 | 0.014114778284940066 | 0.005067671313497431 | 0.00957945892324058 | 6.615415055607877E-4 | 1.2208108282534246E-4 | 4.3195409032534233E-4 | 7.710413256849315E-4 | 0.00255287389307363 |
KO4_2 | 0.2930454225738096 | 0.04448491984630133 | 0.013288408254088674 | 0.0061764226926601 | 0.009670281901613306 | 5.741920558415437E-4 | 1.2517336901067327E-4 | 6.840860150615765E-4 | 0.0011665990316215111 | 0.0028998574836699522 |
KO4_3 | 0.22874484480548932 | 0.04518809672362032 | 0.014879746778969832 | 0.004011997967539857 | 0.008063317544159919 | 5.255733828354182E-4 | 1.0819487842040715E-4 | 3.99380773529556E-4 | 7.700991481089036E-4 | 0.002848024965621781 |
KO4_4 | 0.3400805784677084 | 0.058007658851422284 | 0.017591334847704324 | 0.007814077578269234 | 0.009273361665516828 | 6.415288151762822E-4 | 1.5890199112580128E-4 | 6.968098349919874E-4 | 9.99524380332532E-4 | 0.0035436000647275645 |
KO4_5 | 0.23158293569807994 | 0.030961423640510254 | 0.008592453093713833 | 0.004471638398574434 | 0.007876627879473961 | 4.56550230352446E-4 | 1.2333870398737503E-4 | 4.003674712414519E-4 | 7.107494230089425E-4 | 0.002191681476454497 |
KO9_1 | 0.2740391466009191 | 0.034773700547052436 | 0.007844882379682474 | 0.003074858802724044 | 0.00643948640799248 | 6.975747498851055E-4 | 8.299110475454355E-5 | 4.0917964925005223E-4 | 8.714925608815542E-4 | 0.0021310384563233767 |
KO9_2 | 0.39185000931836844 | 0.057520559461545474 | 0.01200949609718267 | 0.0039203742730985576 | 0.009938481203055486 | 9.15376160420573E-4 | 1.0832002426653154E-4 | 6.493272287408159E-4 | 8.833038516290854E-4 | 0.002479495878550798 |
KO9_3 | 0.20807414538720437 | 0.037038707378441116 | 0.008718819155382347 | 0.0035518196211015494 | 0.00824122081904598 | 7.860029860880256E-4 | 1.1506423299729532E-4 | 5.222160310892551E-4 | 9.77462816124908E-4 | 0.00258668984056061 |
KO9_4 | 0.23889049573719592 | 0.033905521107527654 | 0.00800780878688191 | 0.0036887222331844324 | 0.008370636012295445 | 8.265047762671384E-4 | 1.1264235998230873E-4 | 6.849370798673155E-4 | 8.987858612605042E-4 | 0.0028452444265236626 |
KO9_5 | 0.28808298567264845 | 0.036058805139435726 | 0.007139762001815279 | 0.002864054475789194 | 0.009076249823784938 | 7.05378390449827E-4 | 1.3032395826989622E-4 | 6.486186439126963E-4 | 0.0013842904345222253 | 0.003315355034825659 |
KO21_1 | 0.1454371284680627 | 0.020249954873446326 | 0.009191974780557681 | 0.004103371421990159 | 0.008060546818716968 | 5.230927933260434E-4 | 1.24864297743758E-4 | 4.0184763921268456E-4 | 5.72947168511026E-4 | 0.0022375189983779844 |
KO21_2 | 0.21424070063922618 | 0.034065488286783026 | 0.011640677026206378 | 0.004565294711407438 | 0.009349856924962065 | 5.021527209939304E-4 | 1.4011949756828534E-4 | 3.7385109517071335E-4 | 5.304586198672232E-4 | 0.0021043366285546294 |
KO21_3 | 0.3163648399885701 | 0.027441997063941192 | 0.006365609852236187 | 0.0025185664210007116 | 0.006685231179554186 | 6.315447659900402E-4 | 1.2373600039838748E-4 | 4.490132774389377E-4 | 5.688890808726584E-4 | 0.0022835096589755746 |
KO21_4 | 0.28802903555087805 | 0.03629162669657445 | 0.010813226246644212 | 0.004183110415929757 | 0.009803755139951888 | 6.278356835650711E-4 | 1.649005951888381E-4 | 5.286358714505654E-4 | 8.459675913062305E-4 | 0.0028133214573442386 |
KO21_5 | 0.25183484130767236 | 0.024137661603682737 | 0.009041593001560409 | 0.0026332948509876814 | 0.006407539553105686 | 3.241529201123839E-4 | 1.1303080617678845E-4 | 2.748727714156041E-4 | 4.8015973478279675E-4 | 0.0020659491880657016 |
Mean per clone | ||||||||||
Acylcarnitine chain-length: | C0 | C2:0 | C4:0 | C6:0 | C8:0 | C10:0 | C10:1 | C12:0 | C14:0 | C16:0 |
WT | 0.442801817909138 | 0.06254258887767808 | 0.014223528671357077 | 9.297269082108757E-4 | 3.474526613142546E-4 | 2.9260438946889655E-4 | 1.6757193686285037E-5 | 0.0016121682622370428 | 0.0042011129555933665 | 0.0077033239903616015 |
KO4 | 0.2838012302441887 | 0.044828940299815184 | 0.013693344251883347 | 0.005508361590108211 | 0.00889260958280092 | 5.718771979532956E-4 | 1.2753800507391984E-4 | 5.225196370299828E-4 | 8.836026617513641E-4 | 0.002807207576709485 |
KO9 | 0.28018735654326726 | 0.03985945872680048 | 0.008744153684188936 | 0.0034199658811795556 | 0.008413214853234865 | 7.861674126221338E-4 | 1.0986833605411508E-4 | 5.82855726572027E-4 | 0.0010030671048836554 | 0.002671564727356821 |
KO21 | 0.24318130919088188 | 0.02843734570488555 | 0.009410616181440973 | 0.0036007275642631494 | 0.008061385923258158 | 5.217557767974938E-4 | 1.3333023941521148E-4 | 4.0564413093770104E-4 | 5.99684439067987E-4 | 0.0023009271862636255 |
Replicates vs. mean WT | ||||||||||
Acylcarnitine chain-length: | C0 | C2:0 | C4:0 | C6:0 | C8:0 | C10:0 | C10:1 | C12:0 | C14:0 | C16:0 |
WT_1 | 1.2079796798118168 | 1.170506888902033 | 1.1291237106051664 | 1.192295806639984 | 0.9927129272872057 | 1.270243280272816 | 1.0230353077248404 | 1.1935833583953739 | 1.1693120757382867 | 1.3206853574981268 |
WT_2 | 0.9964676131121352 | 0.9375428545116535 | 1.1086960250327134 | 1.3193074509563618 | 1.227353706388407 | 1.240017772449452 | 1.4184829323544517 | 1.153875932143463 | 1.0952313363068393 | 1.0424758442751407 |
WT_3 | 0.9054012535495757 | 1.0276485564085516 | 0.9847736880015581 | 0.914905743761318 | 1.0901826319732921 | 0.9930339886449518 | 0.8757074460340324 | 0.9520938532532771 | 0.9981051251862386 | 1.0236154069604617 |
WT_4 | 0.8545847319339483 | 0.8987436109902136 | 1.0671937014141315 | 0.8519836678841772 | 0.9865649455673373 | 0.7980719564835699 | 1.0316166093999428 | 0.9939303613949386 | 0.992575373758279 | 0.8869364847035891 |
WT_5 | 1.035566721592524 | 0.9655580891875497 | 0.7102128749464314 | 0.7215073307581589 | 0.7031857887837576 | 0.6986330021492104 | 0.6511577044867327 | 0.7065164948129469 | 0.7447760890103571 | 0.7262869065626815 |
KO4_1 | 0.7352101019211686 | 0.7275458732003651 | 0.9923541907968303 | 5.450709524207951 | 27.57054410521959 | 2.260873484370981 | 7.28529401228202 | 0.2679336273038667 | 0.1835326338127534 | 0.3313990033741 |
KO4_2 | 0.6617981469848933 | 0.7112740397316417 | 0.9342553849417464 | 6.643265498839576 | 27.831940803201938 | 1.9623494264175403 | 7.469828860015009 | 0.4243266854244727 | 0.2776880897878025 | 0.3764423627122855 |
KO4_3 | 0.5165851528920943 | 0.7225172084257659 | 1.046136097643212 | 4.3152434678483855 | 23.206952894417544 | 1.7961910407064687 | 6.456622776220549 | 0.247728964081811 | 0.1833083652472597 | 0.36971377150762835 |
KO4_4 | 0.7680198335082089 | 0.9274905291316723 | 1.2367771214979328 | 8.404701971363064 | 26.68956867516841 | 2.192478439372407 | 9.48261350322966 | 0.43221905015366996 | 0.237918949311221 | 0.4600092205859856 |
KO4_5 | 0.5229945459383825 | 0.4950454433708391 | 0.6041013655786459 | 4.809625664357131 | 22.669643253501867 | 1.5602986379702848 | 7.3603436408521 | 0.2483409955521035 | 0.16918122186232817 | 0.28451113820432955 |
KO9_1 | 0.6188753874022066 | 0.5560003378667849 | 0.5515426277784546 | 3.3072709583518054 | 18.53342087994044 | 2.3840201138173858 | 4.952565823862727 | 0.25380703666891136 | 0.2074432585111162 | 0.2766388196822218 |
KO9_2 | 0.8849331539979703 | 0.9197022460014442 | 0.8443401334977473 | 4.2166944276602125 | 28.603842507531112 | 3.128374670257215 | 6.464090962628564 | 0.40276641337661007 | 0.21025472558481287 | 0.3218735031336009 |
KO9_3 | 0.4699035482051719 | 0.5922157691758185 | 0.6129856631807582 | 3.820282697783277 | 23.718974515472723 | 2.686231014902723 | 6.866557441027247 | 0.323921543006081 | 0.23266758748381494 | 0.3357887898518972 |
KO9_4 | 0.539497549637919 | 0.542118925934465 | 0.5629973385583142 | 3.9675330471856967 | 24.091443077837294 | 2.8246492739473914 | 6.722030078013667 | 0.42485458615647076 | 0.21393994181086223 | 0.369352818352653 |
KO9_5 | 0.6505912442567309 | 0.5765480097083955 | 0.5019684050831297 | 3.0805330581435473 | 26.122263071618544 | 2.410689708825464 | 7.777194720650639 | 0.4023268905025297 | 0.3295056450884472 | 0.43037979954806926 |
KO21_1 | 0.32844745117533847 | 0.3237786480673442 | 0.6462513622985983 | 4.413523353741047 | 23.198978497466687 | 1.787713418364995 | 7.451384765335348 | 0.2492591180619579 | 0.1363798532834504 | 0.2904614944376698 |
KO21_2 | 0.48382976757152324 | 0.5446766579076047 | 0.8184099245110695 | 4.910360957706048 | 26.90972890981992 | 1.7161489679132396 | 8.361751984938055 | 0.23189334756656108 | 0.12626621218574235 | 0.27317254618753867 |
KO21_3 | 0.7144614750734549 | 0.4387729634539552 | 0.44754083176666737 | 2.708931406371067 | 19.24069642830483 | 2.158357115340447 | 7.384052647172031 | 0.27851514507293884 | 0.13541389790894312 | 0.296431730228756 |
KO21_4 | 0.6504694061802181 | 0.5802706179552987 | 0.7602351354920505 | 4.499289392386787 | 28.21608878420664 | 2.1456810156014736 | 9.840585379388516 | 0.32790365859022114 | 0.20136749481584595 | 0.36520876713276845 |
KO21_5 | 0.5687303690323791 | 0.3859395979096997 | 0.6356786146723282 | 2.832331545674067 | 18.441474959117862 | 1.1078197449489762 | 6.745210940021464 | 0.1704988107346754 | 0.11429345981843014 | 0.2681893155020634 |
Mean Clone vs. mean WT (for WT, this should be 1 everywhere) | ||||||||||
Acylcarnitine chain-length: | C0 | C2:0 | C4:0 | C6:0 | C8:0 | C10:0 | C10:1 | C12:0 | C14:0 | C16:0 |
WT | 0.9999999999999998 | 1.0000000000000002 | 1 | 1 | 1 | 1.0000000000000002 | 0.9999999999999998 | 1 | 1.0000000000000002 | 1 |
KO4 | 0.6409215562489494 | 0.716774618772057 | 0.9627248320916735 | 5.924709225323221 | 25.59372994630187 | 1.954438205767536 | 7.610940558519867 | 0.32410986450318474 | 0.21032585200427295 | 0.3644150992768658 |
KO9 | 0.6327601766999997 | 0.6373170577373817 | 0.6147668336196807 | 3.6784628378249073 | 24.213988810480025 | 2.686792956350036 | 6.556487805236569 | 0.3615352939421206 | 0.23876223169581073 | 0.34680674611368845 |
KO21 | 0.5491876938065827 | 0.4546876970587805 | 0.6616231737481427 | 3.8728873311758036 | 23.201393515783188 | 1.7831440524338262 | 7.9565971433710825 | 0.2516140160052709 | 0.1427441836024824 | 0.29869277069775924 |
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area ratio / mg protein | |||||||||||||||||||||||
Acylcarnitine chain-length: | C0 | C2:0 | C3:0 | C4:0 | C5:1 | C5:0 | C6:0 | C8:0 | C10:0 | C10:1 | C12:1 | C12:0 | C14:2 | C14:1 | C14:0 | C16:1 | C16:0 | C18:1-OH | C18:1 | C18:0 | C7-DC | ||
Group | Carnitine | Acetylcarnitine | Propionyl carnitine | Malonyl carnitine | Butyrylcarnitine | Tiglylcarnitine | 2-Methylbutyroylcarnitine | Hexanoylcarnitine | Octanoylcarnitine | Decanoylcarnitine | Decenoylcarnitine | Dodecenoylcarnitine | Lauroylcarnitine | Tetradecadienylcarnitine | Tetradecenoylcarnitine | Myristoylcarnitine | Hexadecenoylcarnitine | Palmitoylcarnitine | Hydroxyoctadecenoylcarnitine | Oleoylcarnitine | Stearoylcarnitine | Pimelylcarnitine | |
WT_1 | 1.6766772794288234 | 0.4646278108171001 | 0.09625961973027766 | 0.04921616592860291 | 0.06738213469017189 | 0.007911860135742618 | 0.09394909820713972 | 0.018770588895548702 | 0.0056813006328779204 | 0.004545762401057735 | 1.3059927192595857E-4 | 0.004168201561921551 | 0.016097595837814015 | 5.13781794623182E-4 | 0.0046273284918466285 | 0.11431548794535037 | 0.02678909867078008 | 0.16456482049184662 | 0.0016921310374614367 | 0.020369523259585718 | 0.014567473401498457 | 9.924842838254738E-5 | |
WT_2 | 1.5255499568597357 | 0.47911976181848176 | 0.09197212541254124 | 0.04011851289933993 | 0.06566532438283827 | 0.00804764049669967 | 0.09258510246369636 | 0.02160655526732673 | 0.006378950607260725 | 0.0044904621666666655 | 8.887001650165015E-5 | 0.005179465427392739 | 0.020705556394389434 | 6.155253300330032E-4 | 0.006029224521452144 | 0.1410602838151815 | 0.030488952836633658 | 0.18383790837953792 | 0.0020189322854785477 | 0.023652352674917488 | 0.01477062432673267 | 1.0916846534653464E-4 | |
WT_3 | 1.645763769186603 | 0.4387449146985646 | 0.0902458808229665 | 0.04136714051674641 | 0.06593530932057416 | 0.007936525129186604 | 0.08968881776076555 | 0.019335103770334927 | 0.00535581638277512 | 0.0036769013397129186 | 1.1768321531100479E-4 | 0.005200372956937799 | 0.015439122698564595 | 8.798566698564593E-4 | 0.005152142832535885 | 0.12013105385645932 | 0.02903348891866029 | 0.18047750742583732 | 0.0018542341626794259 | 0.02210788857416268 | 0.014836350392344499 | 1.1775835406698564E-4 | |
WT_4 | 1.556865247564196 | 0.4494847538226002 | 0.09419892782827055 | 0.032173168163629 | 0.06731019035236938 | 0.008504284482786553 | 0.09724269389064398 | 0.021034068659376265 | 0.006164354342648845 | 0.004503382874038072 | 1.1527989307411907E-4 | 0.004020723296881328 | 0.013148585082219522 | 7.210721425678412E-4 | 0.005269798469015796 | 0.12280066908059942 | 0.03164685356500607 | 0.15841367704981774 | 0.0017458109534224382 | 0.021238594452814903 | 0.014832540108545969 | 1.0410006156338599E-4 | |
WT_5 | 1.777492229618469 | 0.4088429667314702 | 0.08637411934224383 | 0.03398615865208586 | 0.06056929337059538 | 0.007971386671526933 | 0.09234797544430944 | 0.01858373950749291 | 0.00487987216200891 | 0.003720655896314297 | 7.561033778857836E-5 | 0.004326577650870797 | 0.01510728058161199 | 5.382587185095181E-4 | 0.0042039361247468605 | 0.10795012939003644 | 0.025672775752126367 | 0.15326769468772783 | 0.0014834109923045765 | 0.018209925113001214 | 0.013641434784933171 | 1.0125674200081003E-4 | |
KO4_1 | 0.959113312446352 | 0.23714457431759656 | 0.05263911654935623 | 0.01774977052360515 | 0.036426716600858375 | 0.007470325287553649 | 0.0589213666781116 | 0.03787605847210301 | 0.11036438212875538 | 0.012890670369098713 | 8.495436909871246E-4 | 0.004565688326180258 | 0.011160095416309013 | 0.001177096120171674 | 0.004846403982832618 | 0.05523089953648069 | 0.026321949287553652 | 0.09713823177682404 | 6.59130008583691E-4 | 0.01645229059227468 | 0.011488511982832619 | 5.590020600858369E-5 | |
KO4_2 | 0.9307497480515023 | 0.17932542595708156 | 0.050094422815450644 | 0.017609896034334764 | 0.034417638266094425 | 0.006206789562231761 | 0.046139339296137345 | 0.03325565605150215 | 0.10185676345064378 | 0.009443459965665237 | 5.093592961373391E-4 | 0.004061573905579399 | 0.00921402678111588 | 7.113982317596567E-4 | 0.003606976291845494 | 0.04112692595708155 | 0.01858666317596567 | 0.07866355407725323 | 4.907892188841202E-4 | 0.011906245150214594 | 0.009580519399141632 | 4.6848669527897E-5 | |
KO4_3 | 1.052391530934363 | 0.1834103464092664 | 0.057563401498069496 | 0.025293170223938222 | 0.03754805338996139 | 0.006933677590733591 | 0.05708711623166023 | 0.04059971093436294 | 0.11623378943629342 | 0.0115205743011583 | 5.49316555984556E-4 | 0.0037691366795366797 | 0.01219512311969112 | 7.517985328185328E-4 | 0.003545271057915058 | 0.047857107999999995 | 0.019265831552123552 | 0.09427804305791505 | 5.549160926640927E-4 | 0.013738086795366795 | 0.012373969992277993 | 5.2540880308880304E-5 | |
KO4_4 | 0.9564762821655715 | 0.16319705222733244 | 0.06374412591195794 | 0.01543729891852825 | 0.035160068626806824 | 0.006793687219448093 | 0.05506782433771353 | 0.035891239465177395 | 0.10922000858869907 | 0.011444559839684624 | 7.202973889618922E-4 | 0.00417427823653088 | 0.009661331800262811 | 8.942526609724045E-4 | 0.00414474056241787 | 0.06185856868856767 | 0.028544300090670167 | 0.09399008823258868 | 7.53364400788436E-4 | 0.01574114817477004 | 0.011679020084099866 | 5.3989734559789745E-5 | |
KO4_5 | 1.0735094622524668 | 0.19985081881456276 | 0.05002826458387206 | 0.01584832284178292 | 0.03299950248111602 | 0.0066524802776454575 | 0.051437103697856416 | 0.032131379112623336 | 0.09865241883361686 | 0.00888411229533855 | 5.424050820006805E-4 | 0.002946897679482817 | 0.010634015799931949 | 5.233214181694453E-4 | 0.0032061995454236137 | 0.04361231944334808 | 0.01783553102687989 | 0.08171461796529432 | 4.8538841782919356E-4 | 0.012166162076896903 | 0.011489130304185096 | 4.656282408982647E-5 | |
KO9_1 | 1.2512247961590328 | 0.2978940195419847 | 0.11037580152290073 | 0.03215439435496183 | 0.051259781637404564 | 0.008662378552162849 | 0.06741335582442746 | 0.05918635969338421 | 0.10903528077099235 | 0.006695533992366411 | 6.576040572519083E-4 | 0.004778481996183205 | 0.003107373262086513 | 0.0024035720178117045 | 0.0052872896412213734 | 0.009275912774809159 | 0.023323947138676842 | 0.03247913152671755 | 6.684951628498727E-4 | 0.009594472019083967 | 0.0022255812277353687 | 7.924346819338421E-5 | |
KO9_2 | 1.078976781044423 | 0.24016115302652605 | 0.07904490722786833 | 0.025039962123362097 | 0.04046721818983701 | 0.007390082421220838 | 0.05821266466858421 | 0.04731728160818153 | 0.09316762488590605 | 0.0042477038082454465 | 6.323256171300736E-4 | 0.003100458818791946 | 0.0023180999232981785 | 0.0012844370597635028 | 0.0031636643617769258 | 0.00787157425247683 | 0.019104115208692873 | 0.02682566166698626 | 5.929903342921061E-4 | 0.00800559518696069 | 0.0021875767989773093 | 6.753420645573666E-5 | |
KO9_3 | 1.09924557416018 | 0.2629269975593438 | 0.10282961030942425 | 0.036676051441621095 | 0.04480681084721775 | 0.007240584635574139 | 0.055408977664844 | 0.04425500250241234 | 0.08630183166162753 | 0.0035963400707623027 | 6.16423370858797E-4 | 0.0027806815014474106 | 0.001761557619813445 | 0.0011868175760694755 | 0.003153773238983596 | 0.007580368642007076 | 0.021061442368607266 | 0.02464589536313927 | 5.220518340302348E-4 | 0.008216940248311353 | 0.001962654164039884 | 6.968317787069796E-5 | |
KO9_4 | 1.2915965837473549 | 0.37802276746008334 | 0.09501262668162871 | 0.036153708760500156 | 0.04726847073420968 | 0.008761256695094581 | 0.07144749355434434 | 0.049274574499519073 | 0.09876180297403013 | 0.004915335744789996 | 7.009352920807951E-4 | 0.003892770299454953 | 0.002327022357165758 | 0.0016845662250721382 | 0.0036995542378967616 | 0.008534796778454633 | 0.023725173372234686 | 0.029100925286309712 | 6.331143212568131E-4 | 0.009159893196537351 | 0.002193291911510099 | 7.279951651170246E-5 | |
KO9_5 | 1.0432127291830986 | 0.2632134262394366 | 0.09108561507042254 | 0.028832262943661972 | 0.04089372959154929 | 0.007556643661971831 | 0.060573765309859154 | 0.04454968992957746 | 0.08642456174647886 | 0.003343813492957746 | 6.63868985915493E-4 | 0.002357015718309859 | 0.0017316964929577467 | 9.984671971830987E-4 | 0.002120547732394366 | 0.006818500915492957 | 0.01739817190140845 | 0.024291542197183096 | 4.739384366197183E-4 | 0.007187115732394366 | 0.00195405123943662 | 7.226297183098592E-5 | |
KO21_1 | 1.0560860669888643 | 0.26982782977431335 | 0.06560297045879734 | 0.021740348601336303 | 0.02715588514625093 | 0.008144634323682258 | 0.07198446531551597 | 0.03243817562880476 | 0.08019360229992577 | 0.005383844475129919 | 3.2317766443949524E-4 | 0.002129856438010394 | 0.0047017746043058655 | 2.849133273942094E-4 | 0.001447802916109874 | 0.023407619679287308 | 0.013501262087602082 | 0.05686886635486267 | 0.0011160505597624353 | 0.008626021582776542 | 0.00658011474387528 | 4.444975055679288E-5 | |
KO21_2 | 1.066430635896373 | 0.2637025330984456 | 0.071998686880829 | 0.02933082426943005 | 0.03023981388601036 | 0.009311000953367876 | 0.07888393432124352 | 0.036392605637305696 | 0.0966235096165803 | 0.007017366445595854 | 4.2119353367875645E-4 | 0.002053344808290155 | 0.007358058445595853 | 3.018951709844559E-4 | 0.001927257906735751 | 0.03410364310880829 | 0.017099764683937823 | 0.08578752201036269 | 0.0015533228808290154 | 0.010407356248704662 | 0.009130686217616578 | 5.627668393782383E-5 | |
KO21_3 | 1.210327265059937 | 0.29467577687607033 | 0.08153765938350609 | 0.022158816007210456 | 0.025380425694456966 | 0.007990112562415502 | 0.06562577369445698 | 0.03434191205948626 | 0.11303813450563317 | 0.009532329734114466 | 4.5095536547994596E-4 | 0.0028024025128436233 | 0.008029523336638126 | 2.83509905362776E-4 | 0.001931115563767463 | 0.0350104215286165 | 0.0123872660261379 | 0.0818274066408292 | 0.0015475358179360074 | 0.010223544174853537 | 0.01021271432537179 | 4.467786570527265E-5 | |
KO21_4 | 1.0974445063628038 | 0.274561700687566 | 0.06971783557731596 | 0.026299037420218385 | 0.030449007226488196 | 0.009038058365621698 | 0.08093903641000352 | 0.0347189908531173 | 0.07120560858471292 | 0.00523778747868968 | 4.1914665022895387E-4 | 0.0018924558548784783 | 0.0038963713194786896 | 1.9059285804860868E-4 | 0.0012375545389221557 | 0.022823893831630856 | 0.01372013263261712 | 0.06048983009510391 | 0.0011789335047551954 | 0.008434087816836914 | 0.006537812315604086 | 5.616177668193025E-5 | |
KO21_5 | 1.3207692386641876 | 0.32380309944663443 | 0.10649062926441058 | 0.02246001607288955 | 0.03665521116548903 | 0.009826458197099293 | 0.0905295961457791 | 0.042998164049088884 | 0.09583982185496467 | 0.005262655262179249 | 4.643799761993306E-4 | 0.0023200628441799927 | 0.0050457823875046486 | 2.540213923391596E-4 | 0.0011525882960208257 | 0.023504772264782446 | 0.014889839635552252 | 0.06209087653402753 | 9.920126441056156E-4 | 0.00922924276087765 | 0.006502828904425438 | 7.645102268501302E-5 | |
Mean per clone | |||||||||||||||||||||||
Acylcarnitine chain-length: | C0 | C2:0 | C3:0 | Malonyl carnitine | C4:0 | C5:1 | C5:0 | C6:0 | C8:0 | C10:0 | C10:1 | C12:1 | C12:0 | C14:2 | C14:1 | C14:0 | C16:1 | C16:0 | C18:1-OH | C18:1 | C18:0 | C7-DC | |
WT | 1.6364696965315655 | 0.44816404157764345 | 0.09181013462725995 | 0.03937222923208082 | 0.06537245042330982 | 0.008074339383188477 | 0.09316273755331102 | 0.019866011220015908 | 0.005692058825514304 | 0.004187432935557938 | 1.0560854692026218E-4 | 0.0045790681788008426 | 0.016099628118919913 | 6.536989311180008E-4 | 0.005056486087919463 | 0.12125152481752541 | 0.028726233948641294 | 0.1681123216069535 | 0.001758903886269285 | 0.0211156568148964 | 0.014529684602810952 | 1.0630641027205275E-4 | |
KO4 | 0.9944480671700511 | 0.19258564354516794 | 0.05481386627174127 | 0.01838769170843786 | 0.0353103958729674 | 0.00681139198752251 | 0.05373055004829582 | 0.03595080880715377 | 0.1072654724876017 | 0.010836675354189087 | 6.341844028143185E-4 | 0.0039035149654620066 | 0.010572918583462154 | 8.115733927783426E-4 | 0.0038699182880869306 | 0.049937164325095595 | 0.022110855026638586 | 0.08915690702197507 | 5.887176277499066E-4 | 0.014000786557904602 | 0.01132223035250744 | 5.116846289899544E-5 | |
KO9 | 1.1528512928588177 | 0.2884436727654749 | 0.0956697121624489 | 0.03177127592482143 | 0.04493920220004366 | 0.007922189193204848 | 0.06261125140441183 | 0.04891658164661492 | 0.094738220407807 | 0.00455974542182438 | 6.542314646474134E-4 | 0.0033818816668374748 | 0.0022491499310643283 | 0.0015115720151799839 | 0.0034849658424546044 | 0.00801623067264813 | 0.020922569997924027 | 0.02746863120806718 | 5.78118017809749E-4 | 0.008432803276657545 | 0.0021046310683398564 | 7.230466817250144E-5 | |
KO21 | 1.150211542594433 | 0.285314187976606 | 0.07906955631297179 | 0.02439780847421695 | 0.029976068623739093 | 0.008862052880437324 | 0.07759256117739982 | 0.036177969645560575 | 0.09138013537236336 | 0.0064867966791418335 | 4.1577063800529637E-4 | 0.0022396244916405286 | 0.005806302018704636 | 2.6298653082584193E-4 | 0.0015392638443112137 | 0.02777007008262508 | 0.014319653013169436 | 0.0694129003270372 | 0.0012775710814776537 | 0.00938405051680986 | 0.007792831301378635 | 5.5603419913366526E-5 | |
Replicates vs. mean WT | |||||||||||||||||||||||
Acylcarnitine chain-length: | C0 | C2:0 | C3:0 | Malonyl carnitine | C4:0 | C5:1 | C5:0 | C6:0 | C8:0 | C10:0 | C10:1 | C12:1 | C12:0 | C14:2 | C14:1 | C14:0 | C16:1 | C16:0 | C18:1-OH | C18:1 | C18:0 | C7-DC | |
WT_1 | 1.0245697081849279 | 1.0367360334878726 | 1.048463986259057 | 1.250022335247941 | 1.0307420672446674 | 0.9798770847081117 | 1.008440720769704 | 0.9448594731808307 | 0.9981099646075053 | 1.0855725861200098 | 1.2366354403547015 | 0.9102728763067055 | 0.9998737684441599 | 0.7859608914221062 | 0.9151273060756279 | 0.9427962915714813 | 0.9325656373430449 | 0.9788980303097536 | 0.9620372384590743 | 0.9646644401426192 | 1.0026007996539852 | 0.9336071844450111 | |
WT_2 | 0.9322201077680082 | 1.0690722980180802 | 1.001764410714993 | 1.01895456980249 | 1.0044800823226296 | 0.9966933658319592 | 0.9937997196649131 | 1.0876141681404643 | 1.1206754537861539 | 1.0723663484937345 | 0.8415040173666043 | 1.131117778803007 | 1.2860891097265 | 0.941603696644095 | 1.1923743913498877 | 1.1633691537278958 | 1.0613626864956913 | 1.0935421426714387 | 1.1478354793796008 | 1.120133410116399 | 1.0165825845851537 | 1.026922695133412 | |
WT_3 | 1.0056793429629256 | 0.9789828589417363 | 0.9829620791795571 | 1.050667979019083 | 1.008610032110157 | 0.9829318229688467 | 0.962711274015992 | 0.9732755889543611 | 0.9409277990536573 | 0.8780800543670091 | 1.1143341968321878 | 1.1356836705365811 | 0.9589738709815845 | 1.3459662055002415 | 1.0189176323148514 | 0.9907591185945718 | 1.0106959711658803 | 1.073553120322695 | 1.05419868427964 | 1.0469903336639896 | 1.0211061559776886 | 1.1077258066152906 | |
WT_4 | 0.9513559895816659 | 1.00294693934013 | 1.0260188399756613 | 0.8171538363749552 | 1.0296415373220984 | 1.0532483314354188 | 1.043793864848575 | 1.0587967773915021 | 1.0829744617215664 | 1.0754519399695261 | 1.0915773053970628 | 0.8780658290906398 | 0.8167011675734054 | 1.1030645886702217 | 1.0421858930069956 | 1.012776286858292 | 1.1016708149626038 | 0.9423085442849859 | 0.992556197670006 | 1.0058221081634446 | 1.0208439146488029 | 0.9792453841398613 | |
WT_5 | 1.0861748515024723 | 0.91226187021218 | 0.9407906838707316 | 0.8632012795555314 | 0.9265262810004475 | 0.9872493950556622 | 0.9912544207008156 | 0.9354539923328419 | 0.857312320831117 | 0.88852907104972 | 0.7159490400494439 | 0.9448598452630668 | 0.9383620832743498 | 0.823404617763335 | 0.8313947772526371 | 0.8902991492477592 | 0.8937048900327795 | 0.9116981624111266 | 0.8433724002116788 | 0.8623897079135474 | 0.9388665451343702 | 0.9524989296664245 | |
KO4_1 | 0.5860868150990854 | 0.5291468130347797 | 0.5733475586662172 | 0.4508195464112174 | 0.5572181609375579 | 0.9251933728606403 | 0.6324563685603882 | 1.9065759126291624 | 19.38918509310793 | 3.078418345434623 | 8.044270239117646 | 0.9970780403134141 | 0.6931896397776993 | 1.8006701007733381 | 0.958452945101786 | 0.4555068451270953 | 0.916303520141687 | 0.5778174428161974 | 0.3747390711505764 | 0.7791512590159227 | 0.7906924545774394 | 0.525840406665293 | |
KO4_2 | 0.5687546491231646 | 0.40013345409375917 | 0.5456306432708005 | 0.44726692843660665 | 0.52648536261419 | 0.7687055581481839 | 0.4952552974276307 | 1.6739976477006904 | 17.894538087708632 | 2.2551907364235744 | 4.823087818090344 | 0.8869869910176871 | 0.5723130194720316 | 1.0882658635267686 | 0.7133365402632041 | 0.3391868763627883 | 0.6470274944218641 | 0.4679225967812673 | 0.27903128915423936 | 0.5638586218078299 | 0.6593755928664934 | 0.44069468066887785 | |
KO4_3 | 0.6430864764345263 | 0.4092482425935347 | 0.6269830856012922 | 0.6424114335728071 | 0.5743712090769799 | 0.8587300163738658 | 0.6127676980186737 | 2.043677036357298 | 20.420342269704346 | 2.75122598461945 | 5.201440337961543 | 0.8231230749055441 | 0.7574785597289475 | 1.1500684749977415 | 0.701133355510485 | 0.3946928343542187 | 0.6706702864903318 | 0.5608038849070032 | 0.3154897189073218 | 0.6506113883076101 | 0.8516337642927287 | 0.49424000090324705 | |
KO4_4 | 0.5844754010372365 | 0.3641457972684292 | 0.6943038061184941 | 0.39208597581642163 | 0.5378422928792312 | 0.8413923290855446 | 0.5910928101077083 | 1.8066656193677844 | 19.188137708473267 | 2.733072986674529 | 6.820445976836891 | 0.9115999311510649 | 0.6000965816663204 | 1.3679885623233194 | 0.819687919703792 | 0.5101673466099519 | 0.9936666303596775 | 0.5590910132829969 | 0.42831470591969417 | 0.7454728172919147 | 0.8038041019720698 | 0.5078690402735129 | |
KO4_5 | 0.655991042503096 | 0.44593229325369477 | 0.5449100449202242 | 0.40252541323897334 | 0.5047921910136844 | 0.8239039705832204 | 0.5521209986817132 | 1.617404659484412 | 17.331588069928838 | 2.1216130340616 | 5.135996070566273 | 0.6435583757249373 | 0.6605131324390715 | 0.8005541897925779 | 0.6340766076828728 | 0.3596847091942258 | 0.6208795437218627 | 0.486071557302879 | 0.2759607398780183 | 0.576167825777225 | 0.7907350103086462 | 0.43800579824552244 | |
KO9_1 | 0.7645878190173369 | 0.6646986190443287 | 1.2022180554577722 | 0.8166770076803819 | 0.7841190181105234 | 1.0728281461884948 | 0.723608575648082 | 2.9792774723569706 | 19.155684105415144 | 1.5989590986665656 | 6.226807170715267 | 1.0435489950347463 | 0.1930090086015589 | 3.676879222826555 | 1.045645048614556 | 0.07650141133291909 | 0.8119389120194792 | 0.1931989946736548 | 0.3800634975386752 | 0.45437715261196054 | 0.15317477898348886 | 0.7454251158569766 | |
KO9_2 | 0.6593319652244541 | 0.5358777830124478 | 0.8609605851116854 | 0.635980299102783 | 0.6190255670056333 | 0.9152553627616489 | 0.6248492283223522 | 2.38182094453401 | 16.36800105935095 | 1.0143932747377786 | 5.987447375897517 | 0.6770938316982841 | 0.14398468748318483 | 1.9648755698082148 | 0.6256646031985117 | 0.06491938360629253 | 0.6650407165397492 | 0.15956987215788168 | 0.337136292051674 | 0.37913076809019775 | 0.15055913867215637 | 0.6352787784189807 | |
KO9_3 | 0.6717176471339426 | 0.5866757998561833 | 1.1200246108656988 | 0.9315208246257274 | 0.6854081582849924 | 0.8967401903677354 | 0.5947547176051693 | 2.2276742931577234 | 15.161795460508044 | 0.8588412342616115 | 5.836870109804808 | 0.6072592485783014 | 0.1094160440726766 | 1.8155415583129355 | 0.6237084774184051 | 0.06251771805274177 | 0.733177986584052 | 0.14660374163864895 | 0.29680520812170724 | 0.38913969479341853 | 0.13507892412614267 | 0.6554936592475384 | |
KO9_4 | 0.7892578680099266 | 0.8434919636331236 | 1.0348816834587005 | 0.918254045189847 | 0.7230640801764284 | 1.08507411929406 | 0.7669106279048482 | 2.4803456493507214 | 17.35080504286716 | 1.1738303204932574 | 6.6371076254843615 | 0.8501228082772037 | 0.14453888872321807 | 2.5769756456402297 | 0.7316452915267442 | 0.07038919132191428 | 0.8259061530534131 | 0.17310405928690734 | 0.35994821900114016 | 0.43379627149818745 | 0.15095247911202278 | 0.6848083415233236 | |
KO9_5 | 0.6374775722362277 | 0.5873149155672175 | 0.992108501313293 | 0.7322994787445056 | 0.62554989642805 | 0.9358838294195886 | 0.6501930589490965 | 2.242508042313579 | 15.183357093761236 | 0.7985354140393446 | 6.2861293453524665 | 0.5147369784144838 | 0.10756127285466281 | 1.5274113963678226 | 0.4193718118716084 | 0.05623435190406304 | 0.6056544666632625 | 0.14449590586213368 | 0.2694510145321034 | 0.3403690349487065 | 0.1344868311221693 | 0.6797611888695613 | |
KO21_1 | 0.645344102140845 | 0.6020738049943846 | 0.7145504221852947 | 0.5521746933145987 | 0.41540258886437537 | 1.008705968025092 | 0.7726744319242864 | 1.6328479466538217 | 14.088681223824123 | 1.2857147942388647 | 3.060146871289733 | 0.465128789274362 | 0.2920424353641093 | 0.4358479321771737 | 0.28632589726071717 | 0.1930501056750754 | 0.46999763741187073 | 0.33827898997089606 | 0.6345148069060381 | 0.4085130601616506 | 0.45287388706305937 | 0.41812860055230766 | |
KO21_2 | 0.6516653734295428 | 0.5884062723331178 | 0.7842128450539424 | 0.744962244747144 | 0.46257733479771423 | 1.1531594736721424 | 0.8467326786753485 | 1.8319030042950188 | 16.975142488596806 | 1.6758158407761705 | 3.9882523333719475 | 0.44841979374674457 | 0.4570328203388022 | 0.46182601288353653 | 0.3811456954939905 | 0.28126362254109183 | 0.5952664980209358 | 0.5102988358636428 | 0.8831198185158848 | 0.4928739058385631 | 0.6284159957505293 | 0.5293818481294218 | |
KO21_3 | 0.7395965031464861 | 0.6575176710713825 | 0.8881117505658923 | 0.5628031848690769 | 0.38824345010948347 | 0.9895685805642077 | 0.7044208383947883 | 1.728676767527707 | 19.85891888519259 | 2.2764137075891746 | 4.270065052788119 | 0.6120027925807191 | 0.4987396775458443 | 0.4337010386079382 | 0.38190860811050664 | 0.28874211339861167 | 0.43121789122391374 | 0.48674246990736125 | 0.8798296655187915 | 0.48416889251776263 | 0.7028861674943729 | 0.4202744273928152 | |
KO21_4 | 0.670617065924774 | 0.6126366134173636 | 0.7593697129446925 | 0.6679590648829635 | 0.46577735772974804 | 1.1193557685276114 | 0.8687919498252973 | 1.747657869947055 | 12.509640319516402 | 1.2508349528926346 | 3.968870536069613 | 0.41328405277732094 | 0.24201623110162176 | 0.291560608371569 | 0.2447459594279945 | 0.18823593242212114 | 0.4776168242988935 | 0.3598179450315908 | 0.6702660184893712 | 0.3994234179297204 | 0.4499624385748376 | 0.5283009419488864 | |
KO21_5 | 0.8070844461486254 | 0.722510218148629 | 1.1599005893712278 | 0.5704532486717552 | 0.5607134339944966 | 1.2169984107379594 | 0.9717361095574811 | 2.1644085253393133 | 16.837461592169173 | 1.2567736231644382 | 4.397181759824347 | 0.506667023417757 | 0.3134098719693383 | 0.3885908026569888 | 0.22794254270262782 | 0.19385135403579784 | 0.5183359455393044 | 0.36934161601310794 | 0.5639947991755931 | 0.43708054368295673 | 0.44755471864594937 | 0.7191572219338827 | |
Acylcarnitine chain-length: | Mean Clone vs. mean WT (for WT, this should be 1 everywhere) | ||||||||||||||||||||||
C0 | C2:0 | C3:0 | Malonyl carnitine | C4:0 | C5:1 | C5:0 | C6:0 | C8:0 | C10:0 | C10:1 | C12:1 | C12:0 | C14:2 | C14:1 | C14:0 | C16:1 | C16:0 | C18:1-OH | C18:1 | C18:0 | C7-DC | ||
WT | 1 | 0.9999999999999998 | 1 | 1.0000000000000002 | 1.0000000000000002 | 0.9999999999999998 | 1 | 1 | 1 | 1 | 1.0000000000000002 | 1 | 0.9999999999999998 | 0.9999999999999998 | 0.9999999999999998 | 1 | 1 | 1 | 0.9999999999999998 | 1 | 1.0000000000000002 | 0.9999999999999998 | |
KO4 | 0.6076788768394218 | 0.4297213200488395 | 0.5970350277154057 | 0.46702185949520525 | 0.5401418433043287 | 0.843585049410291 | 0.5767386345592228 | 1.8096641751078697 | 18.844758245784604 | 2.5879042174427553 | 6.005048088514539 | 0.8524692826225294 | 0.656718186616814 | 1.241509438282749 | 0.7653374736524279 | 0.41184772232965605 | 0.7697094950270846 | 0.5303412990180687 | 0.33470710500197 | 0.6630523824401005 | 0.7792481848034755 | 0.4813299853512906 | |
KO9 | 0.7044745743243775 | 0.6436118162226603 | 1.04203868724143 | 0.8069463310686491 | 0.6874333440011255 | 0.9811563296063056 | 0.6720632416859097 | 2.462325280342601 | 16.64392855238051 | 1.0889118684397114 | 6.194872325450884 | 0.7385523724006038 | 0.13970198034706022 | 2.312336678591152 | 0.6892070465259651 | 0.06611241124358615 | 0.7283436469719912 | 0.1633945147238453 | 0.32868084624905997 | 0.39936258438849415 | 0.144850430403196 | 0.6801534167832762 | |
KO21 | 0.7028614981580547 | 0.6366289159929756 | 0.8612290640242101 | 0.6196704872971076 | 0.45854283309916355 | 1.0975576403054026 | 0.8328712016754404 | 1.821098822752583 | 16.053968901859818 | 1.5491105837322565 | 3.9369033106687525 | 0.48910049035938075 | 0.3606482072639432 | 0.4023052789394413 | 0.30441374059916737 | 0.22902862561453957 | 0.4984869592989837 | 0.4128959713573198 | 0.7263450217211357 | 0.4444119640261307 | 0.5363386415057497 | 0.5230486079914627 |
A
B
C
D
E
F
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H
I
J
K
L
1
2
3
4
5
6
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8
9
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11
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14
15
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* The data in this sheet are relative means of each clone (WT, KO4, KO9, KO21) to the mean of the WT values in each biological replicate (N1, N2). | |||||||||||
MCAD-KO (average for of biological replicate) vs WT | |||||||||||
KO4 | KO9 | KO21 | |||||||||
Acylcarnitine chain length | N=1 | N=2 | N=1 | N=2 | N=1 | N=2 | |||||
Carnitine | 0.6409215562489494 | 0.6076788768394218 | 0.6327601766999997 | 0.7044745743243775 | 0.5491876938065827 | 0.7028614981580547 | |||||
C2:0 | 0.716774618772057 | 0.4297213200488395 | 0.6373170577373817 | 0.6436118162226603 | 0.4546876970587805 | 0.6366289159929756 | |||||
C4:0 | 0.9627248320916735 | 0.5401418433043287 | 0.6147668336196807 | 0.6874333440011255 | 0.6616231737481427 | 0.45854283309916355 | |||||
C6:0 | 5.924709225323221 | 1.8096641751078697 | 3.6784628378249073 | 2.462325280342601 | 3.8728873311758036 | 1.821098822752583 | |||||
C8:0 | 25.59372994630187 | 18.844758245784604 | 24.213988810480025 | 16.64392855238051 | 23.201393515783188 | 16.053968901859818 | |||||
C10:0 | 1.954438205767536 | 2.5879042174427553 | 2.686792956350036 | 1.0889118684397114 | 1.7831440524338262 | 1.5491105837322565 | |||||
C12:0 | 0.32410986450318474 | 0.656718186616814 | 0.3615352939421206 | 0.13970198034706022 | 0.2516140160052709 | 0.3606482072639432 | |||||
C14:0 | 0.21032585200427295 | 0.41184772232965605 | 0.23876223169581073 | 0.06611241124358615 | 0.1427441836024824 | 0.22902862561453957 | |||||
C16:0 | 0.3644150992768658 | 0.5303412990180687 | 0.34680674611368845 | 0.1633945147238453 | 0.29869277069775924 | 0.4128959713573198 | |||||
C8:0/C10:0 | 13.09518503617813 | 7.281860788652412 | 9.012227292487147 | 15.28491793943746 | 13.011508231270176 | 10.363345955058387 | |||||
MCAD KO (average of each clone) vs WT | |||||||||||
Acylcarnitine chain length | KO4 | KO9 | KO21 | ||||||||
Carnitine | 0.6243002165441855 | 0.6686173755121887 | 0.6260245959823187 | ||||||||
C2:0 | 0.5732479694104482 | 0.640464436980021 | 0.545658306525878 | ||||||||
C4:0 | 0.7514333376980011 | 0.651100088810403 | 0.5600830034236531 | ||||||||
C6:0 | 3.8671867002155453 | 3.070394059083754 | 2.8469930769641936 | ||||||||
C8:0 | 22.219244096043237 | 20.428958681430267 | 19.627681208821503 | ||||||||
C10:0 | 2.2711712116051457 | 1.887852412394874 | 1.6661273180830414 | ||||||||
C12:0 | 0.49041402555999936 | 0.25061863714459043 | 0.30613111163460704 | ||||||||
C14:0 | 0.3110867871669645 | 0.15243732146969843 | 0.18588640460851097 | ||||||||
C16:0 | 0.44737819914746724 | 0.25510063041876685 | 0.3557943710275395 | ||||||||
C8:0/C10:0 | 9.783165611869407 | 10.821268944172756 | 11.780420977314076 | ||||||||