Selected Cell
Cell:
Value:
Note on data sheet
N1
N2
N3
Combined_mean_clone_vs__mean_WT
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The sheets: "N1", "N2", and "N3" contain the normalised data (peak area/mg protein) and all of the data processing steps to get to relative level. | |||||||||
The data used for plotting, were: | |||||||||
Fig. 2: The mean of all of the data points pertaining to a single clone (e.g. all of the data points from KO4 in experiment N1) to the mean of the WT data in the same experiment. | |||||||||
Fig. S3 & S7: Each data point relative to the mean of all of the WT data pionts in one biological replicate (i.e. the ratio of each data point to the mean of all WT data within N0, N1, N2, and N3) | |||||||||
The final data plotted in the figures are summarised in "Combined_mean_clone_vs__mean_WT" | |||||||||
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area ratio / mg protein | ||||||||||||||||||||||||||||||||||||
Acyl-CoA chain length | C0 | C2:0 | C4:0 | C6:0 | C8:0 | C10:0 | C10:1 | C12:0 | C12:1 | C14:0 | C14:1 | C16:0 | C16:1 | C18:0 | C18:1 | C8/C10 | ||||||||||||||||||||
CoA | Acetyl-CoA | Butyryl-CoA | Hexanoyl-CoA | Octanoyl-CoA | Decanoyl-CoA | Decenoyl-CoA | Lauroyl-CoA | Dodecenoyl-CoA | Myristoyl-CoA | Myristoyl-CoA | Palmitoyl-CoA | Palmitoleoyl-CoA | Stearoyl-CoA | Oleoyl-CoA | ||||||||||||||||||||||
WT_1 | 0.0359633744855967 | 0.050497530864197525 | 0.0033460905349794235 | 7.728395061728394E-4 | 8.242798353909464E-4 | 0.0010041152263374484 | 1.6584362139917692E-4 | 0.007860905349794238 | 0.0030732510288065842 | 0.018314814814814815 | 0.010569135802469135 | 0.1047148148148148 | 0.05630246913580246 | 0.0067555555555555554 | 0.03582222222222222 | 0.8209016393442623 | ||||||||||||||||||||
WT_2 | 0.04944 | 0.03876590909090909 | 0.0032204545454545454 | 6.827272727272727E-4 | 6.55E-4 | 7.613636363636363E-4 | 2.0272727272727272E-4 | 0.005151363636363635 | 0.0014754545454545454 | 0.015760454545454546 | 0.007705454545454544 | 0.10260999999999999 | 0.04959636363636363 | 0.006427272727272727 | 0.03113 | 0.8602985074626867 | ||||||||||||||||||||
WT_3 | 0.07225510948905109 | 0.06695182481751824 | 0.0041270072992700725 | 9.48905109489051E-4 | 0.0011613138686131386 | 0.0016262773722627735 | 1.8284671532846716E-4 | 0.0065992700729927 | 0.002225912408759124 | 0.012625912408759123 | 0.0071726277372262765 | 0.07596167883211678 | 0.04032299270072992 | 0.005827007299270073 | 0.03121824817518248 | 0.7140933572710952 | ||||||||||||||||||||
WT_4 | 0.0893696682464455 | 0.038445971563981045 | 0.004535071090047393 | 9.317535545023697E-4 | 9.872037914691945E-4 | 0.0010578199052132702 | 2.4265402843601897E-4 | 0.006172511848341233 | 0.0023483412322274884 | 0.018125118483412323 | 0.012148815165876778 | 0.12330236966824645 | 0.06321090047393366 | 0.008007582938388626 | 0.041271563981042654 | 0.9332437275985664 | ||||||||||||||||||||
WT_5 | 0.04746306306306306 | 0.03196126126126126 | 0.0015045045045045044 | 9.027027027027027E-4 | 0.0013027027027027027 | 0.001352252252252252 | 3.468468468468468E-4 | 0.0043 | 0.0010774774774774773 | 0.011368468468468467 | 0.0065027027027027015 | 0.12354234234234233 | 0.06678648648648648 | 0.009857657657657656 | 0.03355495495495495 | 0.9633577614923385 | ||||||||||||||||||||
KO4_1 | 0.02795747663551402 | 0.019732242990654205 | 9.817757009345793E-4 | 0.0014630841121495326 | 0.017623831775700934 | 0.0014794392523364485 | 2.7383177570093457E-4 | 0.0013261682242990652 | 0.0013490654205607475 | 0.005413084112149533 | 0.00220607476635514 | 0.059339252336448586 | 0.037141588785046725 | 0.005906542056074766 | 0.030599065420560744 | 11.912507896399243 | ||||||||||||||||||||
KO4_2 | 0.024988663967611333 | 0.021373684210526316 | 0.001160323886639676 | 0.0023894736842105264 | 0.017193522267206475 | 0.0012101214574898784 | 3.963562753036437E-4 | 0.0011242914979757083 | 0.00141417004048583 | 0.00517246963562753 | 0.0025817813765182185 | 0.06166396761133603 | 0.03097246963562753 | 0.0063323886639676105 | 0.029941700404858294 | 14.208096353295415 | ||||||||||||||||||||
KO4_3 | 0.04289306122448979 | 0.014499183673469387 | 0.001296734693877551 | 0.0014016326530612243 | 0.023188163265306122 | 0.0018391836734693876 | 2.575510204081633E-4 | 0.0011306122448979591 | 0.0011587755102040816 | 0.0044599999999999996 | 0.0016204081632653058 | 0.055954285714285706 | 0.024599591836734692 | 0.005956326530612245 | 0.025475918367346938 | 12.607856191744341 | ||||||||||||||||||||
KO4_4 | 0.031814018691588786 | 0.015654205607476636 | 9.845794392523363E-4 | 0.002516822429906542 | 0.013977102803738317 | 0.0013789719626168223 | 3.350467289719626E-4 | 0.0012607476635514018 | 8.789719626168224E-4 | 0.005909345794392523 | 0.0031696261682242987 | 0.061929906542056073 | 0.032989252336448595 | 0.007086915887850467 | 0.024218691588785046 | 10.135886140291428 | ||||||||||||||||||||
KO4_5 | 0.036797580645161296 | 0.01601733870967742 | 0.0015306451612903226 | 0.003045967741935484 | 0.015857258064516128 | 0.001560483870967742 | 3.6653225806451613E-4 | 0.0017616935483870967 | 0.0014463709677419354 | 0.00596491935483871 | 0.002630241935483871 | 0.06471975806451613 | 0.03506491935483871 | 0.006495967741935484 | 0.029802016129032258 | 10.16175710594315 | ||||||||||||||||||||
KO9_1 | 0.07760553745928339 | 0.022757654723127036 | 0.0035185667752443 | 0.0037211726384364825 | 0.03633517915309446 | 0.0022534201954397394 | 7.394136807817589E-4 | 0.0023254071661237786 | 0.004360260586319218 | 0.007243973941368078 | 0.008670032573289903 | 0.08650065146579805 | 0.06955960912052117 | 0.008249837133550488 | 0.04220781758957655 | 16.124457935819603 | ||||||||||||||||||||
KO9_2 | 0.07117372549019609 | 0.024587058823529413 | 0.0032658823529411766 | 0.0037262745098039216 | 0.024987450980392158 | 0.0017607843137254903 | 5.090196078431372E-4 | 0.0015737254901960786 | 0.0037278431372549025 | 0.007657254901960785 | 0.007213333333333334 | 0.0898513725490196 | 0.06330627450980392 | 0.01006392156862745 | 0.04089960784313726 | 14.19109131403118 | ||||||||||||||||||||
KO9_3 | 0.08038304498269896 | 0.017486851211072664 | 0.002530795847750865 | 0.0027865051903114184 | 0.01724809688581315 | 0.0011584775086505188 | 3.9238754325259515E-4 | 0.0014484429065743942 | 0.0016325259515570934 | 0.005970242214532871 | 0.003933217993079585 | 0.07579204152249135 | 0.047199653979238754 | 0.009289273356401383 | 0.033867474048442904 | 14.888590203106336 | ||||||||||||||||||||
KO9_4 | 0.09701752577319586 | 0.021205154639175255 | 0.00423573883161512 | 0.0036824742268041235 | 0.025993470790378007 | 0.0017463917525773194 | 3.5670103092783507E-4 | 0.001750171821305842 | 0.0028931271477663227 | 0.007046735395189003 | 0.006983848797250859 | 0.10459450171821305 | 0.06251408934707903 | 0.010254295532646047 | 0.042894158075601374 | 14.884100747737113 | ||||||||||||||||||||
KO9_5 | 0.034624113475177305 | 0.024049290780141848 | 0.0028585106382978728 | 0.004638297872340426 | 0.030286524822695036 | 0.0017680851063829788 | 4.372340425531915E-4 | 0.002242198581560284 | 0.002993617021276596 | 0.007784751773049646 | 0.006891843971631206 | 0.09927021276595746 | 0.05930283687943263 | 0.009747872340425533 | 0.04192482269503546 | 17.12956277577216 | ||||||||||||||||||||
KO21_1 | 0.015872764227642278 | 0.001353658536585366 | 0.0019821138211382114 | 0.013776016260162604 | 0.0012138211382113821 | 2.41869918699187E-4 | 0.0014097560975609756 | 0.0013097560975609756 | 0.006529674796747968 | 0.0039126016260162605 | 0.08613536585365854 | 0.04917520325203252 | 0.007813821138211382 | 0.040022764227642275 | 11.349296718017415 | |||||||||||||||||||||
KO21_2 | 0.01473971119133574 | 0.025316606498194946 | 0.0012180505415162455 | 0.002367870036101083 | 0.0126014440433213 | 9.703971119133574E-4 | 3.1624548736462093E-4 | 0.0020509025270758125 | 0.0018949458483754514 | 0.007050541516245487 | 0.005475090252707582 | 0.08847797833935017 | 0.05390974729241877 | 0.006734296028880866 | 0.03374296028880866 | 12.985863095238095 | ||||||||||||||||||||
KO21_3 | 0.027825978647686832 | 0.025230249110320284 | 0.0016167259786476868 | 0.0017345195729537367 | 0.011576512455516014 | 0.0010046263345195728 | 2.1530249110320282E-4 | 0.0017729537366548043 | 0.0014491103202846976 | 0.006377580071174377 | 0.0048 | 0.08101601423487544 | 0.04747544483985765 | 0.00806868327402135 | 0.03152918149466192 | 11.523202267091747 | ||||||||||||||||||||
KO21_4 | 0.01765328947368421 | 0.02416842105263158 | 0.001243421052631579 | 0.0020082236842105263 | 0.009905263157894736 | 9.019736842105264E-4 | 2.684210526315789E-4 | 0.0017592105263157895 | 0.0015460526315789474 | 0.006279276315789473 | 0.0036832236842105266 | 0.07873651315789473 | 0.04040131578947368 | 0.005776315789473684 | 0.03056019736842105 | 10.981765134938 | ||||||||||||||||||||
KO21_5 | 0.0202553264604811 | 0.027541924398625427 | 0.0015824742268041236 | 0.0021250859106529208 | 0.011197594501718214 | 0.0010298969072164948 | 2.1030927835051546E-4 | 0.001349828178694158 | 0.0014453608247422679 | 0.007088316151202749 | 0.004727491408934708 | 0.08740034364261168 | 0.043702061855670105 | 0.007492439862542955 | 0.03289243986254295 | 10.87253920587254 | ||||||||||||||||||||
area ratio / mg protein - OUTLIERS EXCLUDED | ||||||||||||||||||||||||||||||||||||
Acyl-CoA chain length | C0 | C2:0 | C4:0 | C6:0 | C8:0 | C10:0 | C10:1 | C12:0 | C12:1 | C14:0 | C14:1 | C16:0 | C16:1 | C18:0 | C18:1 | C8/C10 | ||||||||||||||||||||
CoA | Acetyl-CoA | Butyryl-CoA | Hexanoyl-CoA | Octanoyl-CoA | Decanoyl-CoA | Decenoyl-CoA | Lauroyl-CoA | Dodecenoyl-CoA | Myristoyl-CoA | Myristoyl-CoA | Palmitoyl-CoA | Palmitoleoyl-CoA | Stearoyl-CoA | Oleoyl-CoA | ||||||||||||||||||||||
WT_1 | 0.0359633744855967 | 0.050497530864197525 | 0.0033460905349794235 | 7.728395061728394E-4 | 8.242798353909464E-4 | 0.0010041152263374484 | 1.6584362139917692E-4 | 0.007860905349794238 | 0.0030732510288065842 | 0.018314814814814815 | 0.010569135802469135 | 0.1047148148148148 | 0.05630246913580246 | 0.0067555555555555554 | 0.03582222222222222 | 0.8209016393442623 | ||||||||||||||||||||
WT_2 | 0.04944 | 0.03876590909090909 | 0.0032204545454545454 | 6.827272727272727E-4 | 6.55E-4 | 7.613636363636363E-4 | 2.0272727272727272E-4 | 0.005151363636363635 | 0.0014754545454545454 | 0.015760454545454546 | 0.007705454545454544 | 0.10260999999999999 | 0.04959636363636363 | 0.006427272727272727 | 0.03113 | 0.8602985074626867 | ||||||||||||||||||||
WT_3 | 0.07225510948905109 | 0.06695182481751824 | 0.0041270072992700725 | 9.48905109489051E-4 | 0.0011613138686131386 | 0.0016262773722627735 | 1.8284671532846716E-4 | 0.0065992700729927 | 0.002225912408759124 | 0.012625912408759123 | 0.0071726277372262765 | 0.07596167883211678 | 0.04032299270072992 | 0.005827007299270073 | 0.03121824817518248 | 0.7140933572710952 | ||||||||||||||||||||
WT_4 | 0.0893696682464455 | 0.038445971563981045 | 0.004535071090047393 | 9.317535545023697E-4 | 9.872037914691945E-4 | 0.0010578199052132702 | 2.4265402843601897E-4 | 0.006172511848341233 | 0.0023483412322274884 | 0.018125118483412323 | 0.012148815165876778 | 0.12330236966824645 | 0.06321090047393366 | 0.008007582938388626 | 0.041271563981042654 | 0.9332437275985664 | ||||||||||||||||||||
WT_5 | 0.04746306306306306 | 0.03196126126126126 | 9.027027027027027E-4 | 0.0013027027027027027 | 0.001352252252252252 | 3.468468468468468E-4 | 0.0043 | 0.0010774774774774773 | 0.011368468468468467 | 0.0065027027027027015 | 0.12354234234234233 | 0.06678648648648648 | 0.009857657657657656 | 0.03355495495495495 | 0.9633577614923385 | |||||||||||||||||||||
KO4_1 | 0.02795747663551402 | 0.019732242990654205 | 9.817757009345793E-4 | 0.0014630841121495326 | 0.017623831775700934 | 0.0014794392523364485 | 2.7383177570093457E-4 | 0.0013261682242990652 | 0.0013490654205607475 | 0.005413084112149533 | 0.00220607476635514 | 0.059339252336448586 | 0.037141588785046725 | 0.005906542056074766 | 0.030599065420560744 | 11.912507896399243 | ||||||||||||||||||||
KO4_2 | 0.024988663967611333 | 0.021373684210526316 | 0.001160323886639676 | 0.0023894736842105264 | 0.017193522267206475 | 0.0012101214574898784 | 3.963562753036437E-4 | 0.0011242914979757083 | 0.00141417004048583 | 0.00517246963562753 | 0.0025817813765182185 | 0.06166396761133603 | 0.03097246963562753 | 0.0063323886639676105 | 0.029941700404858294 | 14.208096353295415 | ||||||||||||||||||||
KO4_3 | 0.04289306122448979 | 0.014499183673469387 | 0.001296734693877551 | 0.0014016326530612243 | 0.023188163265306122 | 0.0018391836734693876 | 2.575510204081633E-4 | 0.0011306122448979591 | 0.0011587755102040816 | 0.0044599999999999996 | 0.0016204081632653058 | 0.055954285714285706 | 0.024599591836734692 | 0.005956326530612245 | 0.025475918367346938 | 12.607856191744341 | ||||||||||||||||||||
KO4_4 | 0.031814018691588786 | 0.015654205607476636 | 9.845794392523363E-4 | 0.002516822429906542 | 0.013977102803738317 | 0.0013789719626168223 | 3.350467289719626E-4 | 0.0012607476635514018 | 8.789719626168224E-4 | 0.005909345794392523 | 0.0031696261682242987 | 0.061929906542056073 | 0.032989252336448595 | 0.007086915887850467 | 0.024218691588785046 | 10.135886140291428 | ||||||||||||||||||||
KO4_5 | 0.036797580645161296 | 0.01601733870967742 | 0.0015306451612903226 | 0.003045967741935484 | 0.015857258064516128 | 0.001560483870967742 | 3.6653225806451613E-4 | 0.0017616935483870967 | 0.0014463709677419354 | 0.00596491935483871 | 0.002630241935483871 | 0.06471975806451613 | 0.03506491935483871 | 0.006495967741935484 | 0.029802016129032258 | 10.16175710594315 | ||||||||||||||||||||
KO9_1 | 0.07760553745928339 | 0.022757654723127036 | 0.0035185667752443 | 0.0037211726384364825 | 0.03633517915309446 | 0.0022534201954397394 | 7.394136807817589E-4 | 0.0023254071661237786 | 0.004360260586319218 | 0.007243973941368078 | 0.008670032573289903 | 0.08650065146579805 | 0.06955960912052117 | 0.008249837133550488 | 0.04220781758957655 | 16.124457935819603 | ||||||||||||||||||||
KO9_2 | 0.07117372549019609 | 0.024587058823529413 | 0.0032658823529411766 | 0.0037262745098039216 | 0.024987450980392158 | 0.0017607843137254903 | 5.090196078431372E-4 | 0.0015737254901960786 | 0.0037278431372549025 | 0.007657254901960785 | 0.007213333333333334 | 0.0898513725490196 | 0.06330627450980392 | 0.01006392156862745 | 0.04089960784313726 | 14.19109131403118 | ||||||||||||||||||||
KO9_3 | 0.08038304498269896 | 0.017486851211072664 | 0.002530795847750865 | 0.0027865051903114184 | 0.01724809688581315 | 0.0011584775086505188 | 3.9238754325259515E-4 | 0.0014484429065743942 | 0.0016325259515570934 | 0.005970242214532871 | 0.003933217993079585 | 0.07579204152249135 | 0.047199653979238754 | 0.009289273356401383 | 0.033867474048442904 | 14.888590203106336 | ||||||||||||||||||||
KO9_4 | 0.09701752577319586 | 0.021205154639175255 | 0.00423573883161512 | 0.0036824742268041235 | 0.025993470790378007 | 0.0017463917525773194 | 3.5670103092783507E-4 | 0.001750171821305842 | 0.0028931271477663227 | 0.007046735395189003 | 0.006983848797250859 | 0.10459450171821305 | 0.06251408934707903 | 0.010254295532646047 | 0.042894158075601374 | 14.884100747737113 | ||||||||||||||||||||
KO9_5 | 0.034624113475177305 | 0.024049290780141848 | 0.0028585106382978728 | 0.004638297872340426 | 0.030286524822695036 | 0.0017680851063829788 | 4.372340425531915E-4 | 0.002242198581560284 | 0.002993617021276596 | 0.007784751773049646 | 0.006891843971631206 | 0.09927021276595746 | 0.05930283687943263 | 0.009747872340425533 | 0.04192482269503546 | 17.12956277577216 | ||||||||||||||||||||
KO21_1 | 0.015872764227642278 | 0.001353658536585366 | 0.0019821138211382114 | 0.013776016260162604 | 0.0012138211382113821 | 2.41869918699187E-4 | 0.0014097560975609756 | 0.0013097560975609756 | 0.006529674796747968 | 0.0039126016260162605 | 0.08613536585365854 | 0.04917520325203252 | 0.007813821138211382 | 0.040022764227642275 | 11.349296718017415 | |||||||||||||||||||||
KO21_2 | 0.01473971119133574 | 0.025316606498194946 | 0.0012180505415162455 | 0.002367870036101083 | 0.0126014440433213 | 9.703971119133574E-4 | 3.1624548736462093E-4 | 0.0020509025270758125 | 0.0018949458483754514 | 0.007050541516245487 | 0.005475090252707582 | 0.08847797833935017 | 0.05390974729241877 | 0.006734296028880866 | 0.03374296028880866 | 12.985863095238095 | ||||||||||||||||||||
KO21_3 | 0.027825978647686832 | 0.025230249110320284 | 0.0016167259786476868 | 0.0017345195729537367 | 0.011576512455516014 | 0.0010046263345195728 | 2.1530249110320282E-4 | 0.0017729537366548043 | 0.0014491103202846976 | 0.006377580071174377 | 0.0048 | 0.08101601423487544 | 0.04747544483985765 | 0.00806868327402135 | 0.03152918149466192 | 11.523202267091747 | ||||||||||||||||||||
KO21_4 | 0.01765328947368421 | 0.02416842105263158 | 0.001243421052631579 | 0.0020082236842105263 | 0.009905263157894736 | 9.019736842105264E-4 | 2.684210526315789E-4 | 0.0017592105263157895 | 0.0015460526315789474 | 0.006279276315789473 | 0.0036832236842105266 | 0.07873651315789473 | 0.04040131578947368 | 0.005776315789473684 | 0.03056019736842105 | 10.981765134938 | ||||||||||||||||||||
KO21_5 | 0.0202553264604811 | 0.027541924398625427 | 0.0015824742268041236 | 0.0021250859106529208 | 0.011197594501718214 | 0.0010298969072164948 | 2.1030927835051546E-4 | 0.001349828178694158 | 0.0014453608247422679 | 0.007088316151202749 | 0.004727491408934708 | 0.08740034364261168 | 0.043702061855670105 | 0.007492439862542955 | 0.03289243986254295 | 10.87253920587254 | ||||||||||||||||||||
AVERAGE | ||||||||||||||||||||||||||||||||||||
Acyl-CoA chain length | C0 | C2:0 | C4:0 | C6:0 | C8:0 | C10:0 | C10:1 | C12:0 | C12:1 | C14:0 | C14:1 | C16:0 | C16:1 | C18:0 | C18:1 | C8/C10 | ||||||||||||||||||||
WT | 0.05889824305683128 | 0.04532449951957343 | 0.0038071558674378585 | 8.477856291188472E-4 | 9.861000396351966E-4 | 0.0011603656784858762 | 2.2818369694755655E-4 | 0.006016810181498361 | 0.0020400873385450443 | 0.015238953744181855 | 0.008819747190745887 | 0.10602624113150408 | 0.05524384248666323 | 0.007375015235628927 | 0.03459939786668046 | 0.8498183442670648 | ||||||||||||||||||||
KO4 | 0.03289016023287304 | 0.017455331038360795 | 0.001190811776398893 | 0.002163396124252662 | 0.017567975635293595 | 0.0014936400433760559 | 3.258636116898441E-4 | 0.0013207026358222462 | 0.0012494707803218832 | 0.005383963779401659 | 0.002441626481969367 | 0.060721434053728505 | 0.03215356438973925 | 0.006355628176088114 | 0.028007478382116657 | 11.761853676328146 | ||||||||||||||||||||
KO9 | 0.07216078943611032 | 0.022017202035409245 | 0.0032818988891698667 | 0.0037109448875392746 | 0.02697014452647456 | 0.0017374317753552095 | 4.869511810717036E-4 | 0.0018679891931520753 | 0.003121474768834826 | 0.007140591645220076 | 0.006738455333716978 | 0.09120175600429589 | 0.060376492767215094 | 0.009521039986330181 | 0.040358776050358716 | 15.522994864624623 | ||||||||||||||||||||
KO21 | 0.019269414000166032 | 0.02556430026494306 | 0.001402866067237 | 0.0020435626050112955 | 0.011811366083722574 | 0.0010241430352142668 | 2.50429645629821E-4 | 0.001668530213260308 | 0.001529045144508468 | 0.006665077770232011 | 0.004519681394373816 | 0.08435324304567812 | 0.04693275460589054 | 0.007177111218626048 | 0.033749508648415374 | 11.53292623940117 | ||||||||||||||||||||
Replicates vs. mean WT | ||||||||||||||||||||||||||||||||||||
Acyl-CoA chain length | C0 | C2:0 | C4:0 | C6:0 | C8:0 | C10:0 | C10:1 | C12:0 | C12:1 | C14:0 | C14:1 | C16:0 | C16:1 | C18:0 | C18:1 | C8/C10 | ||||||||||||||||||||
WT_1 | 0.6106018213632521 | 1.1141332259474839 | 0.8788950732482821 | 0.9115977903235944 | 0.8358987955176285 | 0.8653437833904963 | 0.7267987310999381 | 1.306490501223797 | 1.5064311075026693 | 1.2018420110899874 | 1.1983490653290825 | 0.9876311156304908 | 1.0191627989923908 | 0.9160056406282738 | 1.0353423594321955 | 0.9659730751661499 | ||||||||||||||||||||
WT_2 | 0.8394138336570589 | 0.8552970137964345 | 0.8458951137248416 | 0.8053064940919921 | 0.6642328097282243 | 0.6561411204070731 | 0.888438900058077 | 0.8561618999057066 | 0.7232310683849519 | 1.0342215620591275 | 0.8736593440614132 | 0.967779286570511 | 0.8977717950799133 | 0.8714928067161641 | 0.8997266403291508 | 1.0123322393148155 | ||||||||||||||||||||
WT_3 | 1.226778690483716 | 1.4771663344810908 | 1.0840132221976684 | 1.1192748224280507 | 1.1776836243133726 | 1.4015214362293535 | 0.8013136686557008 | 1.0968054291101619 | 1.0910868209919908 | 0.8285288229567351 | 0.8132464096875872 | 0.7164422507245325 | 0.7299092692631681 | 0.7901010524181183 | 0.9022772100102338 | 0.8402894125414213 | ||||||||||||||||||||
WT_4 | 1.5173571164119812 | 0.8482381928426614 | 1.191196590829208 | 1.0990438177995483 | 1.0011193102014337 | 0.9116263302389168 | 1.0634152732295687 | 1.0258777761215825 | 1.1510983808675004 | 1.189393890662106 | 1.377456167748653 | 1.162942007114209 | 1.1442162172045474 | 1.0857717147082957 | 1.1928405268806008 | 1.098168489647576 | ||||||||||||||||||||
WT_5 | 0.805848538083991 | 0.7051652329323296 | 1.064777075356814 | 1.3210654602393404 | 1.1653673297341598 | 1.5200334269567146 | 0.7146643936387528 | 0.5281526222528865 | 0.7460137132320441 | 0.7372890131732639 | 1.1652053399602564 | 1.2089399194599801 | 1.3366287855291479 | 0.9698132633478193 | 1.1336043379049403 | |||||||||||||||||||||
KO4_1 | 0.4746742039238365 | 0.43535490076692 | 0.2578764135536419 | 1.725771305737042 | 17.872255417635714 | 1.2749767420447329 | 1.2000496940141578 | 0.22041051392597044 | 0.6612782673916686 | 0.3552136323148968 | 0.2501290250892749 | 0.5596657176863439 | 0.6723208798159417 | 0.8008854039433136 | 0.884381443239737 | 14.017710934062404 | ||||||||||||||||||||
KO4_2 | 0.42426841057889647 | 0.47157022001524956 | 0.3047744634160595 | 2.818488073092304 | 17.435880312475337 | 1.0428793956306317 | 1.7370052313366553 | 0.18685839573814295 | 0.6931909304894721 | 0.339424196861438 | 0.2927273674269429 | 0.5815915659487954 | 0.5606501691678089 | 0.8586271975921683 | 0.8653821237071998 | 16.718980531715097 | ||||||||||||||||||||
KO4_3 | 0.7282570582470858 | 0.319897270287737 | 0.34060457176664743 | 1.6532866386494691 | 23.515021126948216 | 1.5850035101600721 | 1.1287003578847101 | 0.1879089103350114 | 0.5680028929695239 | 0.2926710110727124 | 0.18372501254520288 | 0.5277399737757915 | 0.445291108102653 | 0.8076358272233861 | 0.7363110325073167 | 14.835942618558237 | ||||||||||||||||||||
KO4_4 | 0.5401522531137515 | 0.34538066108631493 | 0.2586128526213819 | 2.9687014540720886 | 14.17412254532419 | 1.1883943037820615 | 1.4683201887511113 | 0.2095375498845202 | 0.43085016313256974 | 0.38777897049846205 | 0.35937834721045364 | 0.5840998028520559 | 0.5971570921123516 | 0.9609357623579348 | 0.699974366088835 | 11.927120906095801 | ||||||||||||||||||||
KO4_5 | 0.6247653365424684 | 0.35339251132293953 | 0.40204425943832367 | 3.5928513498174475 | 16.08078027294518 | 1.3448207749508476 | 1.6063034430928527 | 0.2927952677989226 | 0.708975022987723 | 0.3914257799434611 | 0.29822191935882814 | 0.6104126428875695 | 0.6347299133528583 | 0.880807365733058 | 0.8613449356507985 | 11.957563842314173 | ||||||||||||||||||||
KO9_1 | 1.3176205847838505 | 0.5021049314245405 | 0.9241982460813265 | 4.389284874177584 | 36.8473559402112 | 1.9419914232383664 | 3.2404316814610046 | 0.3864850470560606 | 2.137291136480893 | 0.4753590084315195 | 0.983025067020847 | 0.8158419136873061 | 1.2591377787907132 | 1.1186196733120317 | 1.2199003506423176 | 18.97400549728815 | ||||||||||||||||||||
KO9_2 | 1.208418482390385 | 0.5424672987930395 | 0.8578273300743664 | 4.395302753217054 | 25.339671408629247 | 1.517439154201011 | 2.2307448544850477 | 0.2615547844662394 | 1.8272958548497913 | 0.5024790435422302 | 0.8178616889270838 | 0.8474446664347666 | 1.1459426365044592 | 1.3645967156797634 | 1.1820901623991542 | 16.698970326735466 | ||||||||||||||||||||
KO9_3 | 1.3647783161398697 | 0.3858145461379215 | 0.6647471067303691 | 3.28680399219269 | 17.49122420905085 | 0.9983727803481561 | 1.7196125249157375 | 0.2407326910575214 | 0.8002235594096591 | 0.39177507293191144 | 0.44595586562917705 | 0.7148422948285668 | 0.8543875996792497 | 1.2595598869443165 | 0.9788457642801234 | 17.51973266233405 | ||||||||||||||||||||
KO9_4 | 1.647205769441765 | 0.46785193138244774 | 1.1125730017630429 | 4.343638415564478 | 26.359871965925667 | 1.505035683971737 | 1.5632187386718328 | 0.2908803449853886 | 1.4181388674416517 | 0.4624159580430124 | 0.791842288243665 | 0.9864963673331091 | 1.1316028453699787 | 1.3904100812032534 | 1.2397371260876433 | 17.51444982112509 | ||||||||||||||||||||
KO9_5 | 0.5878632651532285 | 0.5306024563990196 | 0.7508257444215423 | 5.4710739519862805 | 30.713440427301276 | 1.5237309575461557 | 1.9161493498533375 | 0.3726556952810353 | 1.4673965004908038 | 0.5108455543427199 | 0.7814106031137115 | 0.9362796578144543 | 1.073474150422272 | 1.321742671572156 | 1.2117211651076 | 20.1567345437168 | ||||||||||||||||||||
KO21_1 | 0.2694946980392361 | 0.3555563742905939 | 2.3379894080044 | 13.970201507403834 | 1.0460677704594454 | 1.0599789640307913 | 0.2343029038702207 | 0.6420098163518192 | 0.42848576787897663 | 0.44361834204517275 | 0.8123966759023841 | 0.8901481330503797 | 1.0594989825190557 | 1.156747420341224 | 13.354967911178408 | |||||||||||||||||||||
KO21_2 | 0.2502572305444375 | 0.5585633987477775 | 0.319937135207435 | 2.793005631107651 | 12.779072646608096 | 0.8362856036724537 | 1.3859249876090123 | 0.34086209556391195 | 0.9288552566219516 | 0.4626657206658524 | 0.6207763254770291 | 0.8344913239884753 | 0.9758507892609655 | 0.9131229988986699 | 0.9752470380793373 | 15.280751683982412 | ||||||||||||||||||||
KO21_3 | 0.4724415738655799 | 0.5566580850920279 | 0.4246545281939591 | 2.0459412301627755 | 11.739693733101051 | 0.865784255038013 | 0.9435489650809092 | 0.29466672259441085 | 0.7103177853739235 | 0.4185051138178893 | 0.5442332865318856 | 0.7641128589515069 | 0.8593798458410817 | 1.0940564888654456 | 0.9112638785261871 | 13.559606408626141 | ||||||||||||||||||||
KO21_4 | 0.2997252304563727 | 0.5332308422334464 | 0.3266010365549801 | 2.368787126408111 | 10.04488668468074 | 0.7773184789362977 | 1.1763375570747727 | 0.2923825869935779 | 0.7578364917854771 | 0.4120542933065116 | 0.41761102722707816 | 0.7426134541564859 | 0.7313270397370932 | 0.7832276415604029 | 0.8832580695819219 | 12.922485386461439 | ||||||||||||||||||||
KO21_5 | 0.34390374668624 | 0.6076608609154398 | 0.4156578511373368 | 2.50663120211373 | 11.355434592478787 | 0.887562366167512 | 0.9216665395637395 | 0.22434282252161916 | 0.708479876049363 | 0.46514454142949463 | 0.5360121221949564 | 0.8243274750654346 | 0.7910757088669294 | 1.0159219504180472 | 0.9506650950772375 | 12.793956825266795 | ||||||||||||||||||||
Mean Clone vs. mean WT (for WT, this should be 1 everywhere) | ||||||||||||||||||||||||||||||||||||
Acyl-CoA chain length | C0 | C2:0 | C4:0 | C6:0 | C8:0 | C10:0 | C10:1 | C12:0 | C12:1 | C14:0 | C14:1 | C16:0 | C16:1 | C18:0 | C18:1 | C8/C10 | ||||||||||||||||||||
WT | 0.9999999999999998 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0.9999999999999997 | 1 | 1 | 1 | 1 | 1 | 1.0000000000000002 | 1 | ||||||||||||||||||||
KO4 | 0.5584234524812077 | 0.3851191126958322 | 0.31278251215921093 | 2.55181976427367 | 17.815611935065725 | 1.2872149453136692 | 1.4280757830158974 | 0.21950212753651352 | 0.6124594553941914 | 0.353302718138194 | 0.2768363343261405 | 0.5727019406301113 | 0.5820298325103226 | 0.8617783113699723 | 0.8094787802387774 | 13.840432788577052 | ||||||||||||||||||||
KO9 | 1.2251772835818198 | 0.48576823282739373 | 0.8620342858141294 | 4.377220797427617 | 27.350312790223644 | 1.4973139998610852 | 2.1340314298773917 | 0.3104617125692491 | 1.53006918373456 | 0.4685749274582787 | 0.7640191025868968 | 0.8601809800196406 | 1.0929090021533345 | 1.290985805742304 | 1.1664589137033679 | 18.266250627965206 | ||||||||||||||||||||
KO21 | 0.3271644959183732 | 0.5640282967471729 | 0.368481385076861 | 2.4104709195593337 | 11.9778578328545 | 0.8826036948547445 | 1.0974914026718452 | 0.27731142630874805 | 0.7494998452365069 | 0.43737108741974495 | 0.5124502206952244 | 0.7955883576128574 | 0.8495563033512898 | 0.9731656124523242 | 0.9754363003211817 | 13.571048821437088 |
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area ratio / mg protein | |||||||||||||||||
Acyl-CoA chain length | C0 | C2:0 | C4:0 | C6:0 | C8:0 | C8:1 | C10:0 | C10:1 | C12:0 | C12:1 | C14:0 | C14:1 | C16:0 | C16:1 | C18:0 | C18:1 | C8/C10 |
CoA | Acetyl-CoA | Butyryl-CoA | Hexanoyl-CoA | Octanoyl-CoA | Octenoyl-CoA | Decanoyl-CoA | Decenoyl-CoA | Lauroyl-CoA | Dodecenoyl-CoA | Myristoyl-CoA | Myristoyl-CoA | Palmitoyl-CoA | Palmitoleoyl-CoA | Stearoyl-CoA | Oleoyl-CoA | ||
WT_1 | 0.028195996140858656 | 0.048741437530149534 | 0.0015763844669561022 | 5.336878919440424E-4 | 5.275180897250361E-4 | 1.3758658948383984E-4 | 2.9121466473709597E-4 | 2.1995344910757353E-4 | 0.002631420646406174 | 0.0010180173661360347 | 0.01070460684997588 | 0.0030447973950795946 | 0.06910178485287023 | 0.035476362759286055 | 0.006385745296671489 | 0.0342424023154848 | 1.8114406779661016 |
WT_2 | 0.039968750000000004 | 0.04289329268292683 | 0.0017937195121951219 | 4.451803861788618E-4 | 9.293546747967481E-4 | 5.134197154471545E-4 | 9.423526422764228E-5 | 0.004776753048780488 | 0.0012120604674796748 | 0.010755818089430894 | 0.005491641260162602 | 0.07148882113821138 | 0.033469766260162605 | 0.0072788617886178865 | 0.02866051829268293 | 1.8101265822784811 | |
WT_3 | 0.022494040697674418 | 0.04151792635658915 | 0.0015646681201550387 | 4.3376937984496123E-4 | 4.2757267441860465E-4 | 6.971293604651163E-6 | 5.081298449612404E-4 | 2.010830910852713E-4 | 0.0030983527131782946 | 9.016206395348837E-4 | 0.011990625 | 0.003315237403100775 | 0.05762936046511628 | 0.03439171511627907 | 0.006010804263565892 | 0.0265218992248062 | 0.8414634146341462 |
WT_4 | 0.035885611510791365 | 0.037725899280575535 | 0.0017636091127098319 | 0.001042829736211031 | 4.6313908872901675E-4 | 2.0979280575539565E-5 | 5.796906474820143E-4 | 4.539376498800958E-5 | 0.003251175059952038 | 6.778393285371702E-4 | 0.010244268585131893 | 0.0035885611510791363 | 0.07606522781774579 | 0.035578896882494 | 0.00598093525179856 | 0.030027362110311748 | 0.7989417989417991 |
WT_5 | 0.03836332811684924 | 0.04270005216484089 | 0.002315143453312467 | 6.538445487741261E-4 | 6.204851330203442E-4 | 7.806103286384975E-5 | 5.704460093896713E-4 | 1.1575717266562335E-4 | 0.0035027386541471046 | 0.001611259780907668 | 0.011442279603547207 | 0.003903051643192488 | 0.07405790297339593 | 0.035360980699008865 | 0.004603599374021909 | 0.029222848200312984 | 1.087719298245614 |
KO4_1 | 0.013707720254314259 | 0.010629291553133515 | 6.911943687556767E-4 | 0.0018325363306085376 | 0.02488880563124432 | 3.0203451407811077E-4 | 0.0011123001816530427 | 4.2691416893732965E-4 | 0.0016960399636693913 | 0.00126622161671208 | 0.003020345140781108 | 0.0019080449591280654 | 0.033978882833787465 | 0.02128762488646685 | 0.005082311534968211 | 0.02346575840145322 | 22.375979112271537 |
KO4_2 | 0.025339665032679735 | 0.008777450980392155 | 7.262295751633986E-4 | 0.0016248733660130716 | 0.02549640522875817 | 3.657271241830065E-4 | 0.0010553839869281044 | 2.2178737745098037E-4 | 0.002238772467320261 | 0.001381926062091503 | 0.004153615196078431 | 0.0018704330065359473 | 0.03814011437908496 | 0.015151552287581698 | 0.004284232026143791 | 0.01794675245098039 | 24.158415841584162 |
KO4_3 | 0.007521821071752951 | 0.00789936421435059 | 5.372729336966394E-4 | 0.0014433764759309716 | 0.023843301544050864 | 6.098773841961853E-4 | 0.0015595435967302451 | 2.9913033605812896E-4 | 0.002181037693006358 | 0.0010745458673932788 | 0.00563410535876476 | 0.0017599318801089917 | 0.02962261580381471 | 0.010425999091734786 | 0.0029332198001816526 | 0.01681519073569482 | 15.288640595903168 |
KO4_4 | 0.018517508417508415 | 0.007455450336700335 | 0.0011465782828282826 | 0.0017629313973063971 | 0.023362205387205383 | 7.32087542087542E-4 | 0.0010927483164983164 | 3.848842592592592E-4 | 0.0032028829966329964 | 0.001081982323232323 | 0.0046832070707070695 | 9.823968855218854E-4 | 0.027184132996632995 | 0.013161426767676765 | 0.003687352693602693 | 0.013457491582491581 | 21.379310344827584 |
KO4_5 | 0.004685282776349614 | 0.008740381319622962 | 7.151221079691515E-4 | 0.0020028898886032555 | 0.026878727506426732 | 4.055098543273349E-4 | 0.0013425664095972575 | 3.150921165381319E-4 | 0.0021015274207369316 | 7.014224507283632E-4 | 0.006384040274207368 | 0.0018110946872322191 | 0.028221293916023984 | 0.013507862039417305 | 0.002528956726649528 | 0.016823179091688085 | 20.02040816326531 |
KO9_1 | 0.01051991341991342 | 0.014672510822510825 | 9.096165739022882E-4 | 0.0037294279529993817 | 0.0391135126777984 | 5.022665429808288E-4 | 0.0016610389610389612 | 5.25995670995671E-4 | 0.004113048855905999 | 0.002440145330859617 | 0.005220408163265307 | 0.004152597402597403 | 0.05062213976499692 | 0.026299783549783556 | 0.004587631416202845 | 0.025350618429189863 | 23.547619047619047 |
KO9_2 | 0.01947715736040609 | 0.015184968979131415 | 0.0011289537507050197 | 0.0031993034404963335 | 0.050857021996615896 | 8.151551043429215E-4 | 0.001987391426959955 | 5.121771009588269E-4 | 0.004328257191201354 | 0.002247086858432036 | 0.005951353637901861 | 0.0036790186125211506 | 0.059874224478285394 | 0.03181269035532995 | 0.005121771009588268 | 0.02492354765933446 | 25.589836660617053 |
KO9_3 | 0.011312218813905931 | 0.01579133435582822 | 7.519683026584868E-4 | 0.003069992331288344 | 0.04250255623721882 | 7.715848670756647E-4 | 0.002262443762781186 | 5.296472392638037E-4 | 0.004086784253578733 | 0.0018079933537832314 | 0.006211912065439673 | 0.0027267024539877303 | 0.04904141104294479 | 0.029163292433537834 | 0.006538854805725972 | 0.02994795501022495 | 18.78612716763006 |
KO9_4 | 0.011988713534194163 | 0.01666798182687709 | 7.523529411764705E-4 | 0.003058345289335246 | 0.04679268292682926 | 6.391941654710664E-4 | 0.002575126733620277 | 3.009411764705882E-4 | 0.004434600669536107 | 0.001938990913438546 | 0.004923935915829745 | 0.003055286944045911 | 0.04251099952175992 | 0.028412027737924433 | 0.006269607843137254 | 0.02299875657580105 | 18.171021377672208 |
KO9_5 | 0.00992504 | 0.0184176 | 8.08328E-4 | 0.0028615493333333333 | 0.041951199999999994 | 3.444773333333333E-4 | 0.0018656346666666664 | 2.6807839999999996E-4 | 0.003547093333333333 | 0.0028342639999999995 | 0.0067190133333333325 | 0.0035129866666666664 | 0.05184213333333333 | 0.025000186666666667 | 0.005457066666666666 | 0.027421759999999996 | 22.486288848263253 |
KO21_1 | 0.013729378531073446 | 0.013701586266840505 | 0.0013673794002607561 | 0.003390656236418949 | 0.03168318122555411 | 2.945980008691873E-4 | 0.0013229117774880487 | 1.3312494567579313E-4 | 0.004863646240764886 | 0.0012589895697522817 | 0.007170404172099088 | 0.0026430443285528032 | 0.048080617122990006 | 0.02039952194697958 | 0.004613515862668405 | 0.020899782703172536 | 23.949579831932773 |
KO21_2 | 0.006711394302848576 | 0.017865092453773112 | 9.779460269865067E-4 | 0.0034835332333833084 | 0.026653823088455774 | 2.863528235882059E-4 | 0.0020134182908545725 | 3.2598200899550226E-4 | 0.004602098950524738 | 0.0013678460769615192 | 0.00779800099950025 | 0.0023777511244377813 | 0.060722138930534734 | 0.020038305847076464 | 0.004474262868565717 | 0.0255672163918041 | 13.23809523809524 |
KO21_3 | 0.011540870488322719 | 0.019225732484076434 | 0.0011649490445859874 | 0.0026557579617834397 | 0.024439490445859875 | 1.9171422505307858E-4 | 0.0013305944798301488 | 1.7080488322717622E-4 | 0.002457526539278132 | 8.03787685774947E-4 | 0.007277537154989386 | 0.002522698513800425 | 0.04887898089171975 | 0.01778651804670913 | 0.004969363057324841 | 0.024466645435244162 | 18.36734693877551 |
KO21_4 | 0.005767689446768943 | 0.012724593212459317 | 9.543444909344489E-4 | 0.0028719525801952574 | 0.027916806136680607 | 2.1257205950720592E-4 | 0.0020603138075313806 | 2.7916806136680605E-4 | 0.005410925151092514 | 0.0016500348675034865 | 0.009335332403533238 | 0.0034487215248721515 | 0.0600553231055323 | 0.019532845188284513 | 0.005410925151092514 | 0.020157182705718264 | 13.549783549783548 |
KO21_5 | 0.008084667541557304 | 0.014490857392825896 | 9.427449693788277E-4 | 0.0026575896762904634 | 0.02881386701662292 | 2.6995516185476814E-4 | 0.0018435279965004375 | 1.454680664916885E-4 | 0.00388847331583552 | 0.0022631474190726157 | 0.006993657042869641 | 0.003077209098862642 | 0.051473315835520554 | 0.018239457567804023 | 0.003944422572178478 | 0.023498687664041996 | 15.629742033383913 |
area ratio / mg protein - OUTLIERS EXCLUDED | |||||||||||||||||
Acyl-CoA chain length | C0 | C2:0 | C4:0 | C6:0 | C8:0 | C8:1 | C10:0 | C10:1 | C12:0 | C12:1 | C14:0 | C14:1 | C16:0 | C16:1 | C18:0 | C18:1 | C8/C10 |
CoA | Acetyl-CoA | Butyryl-CoA | Hexanoyl-CoA | Octanoyl-CoA | Octenoyl-CoA | Decanoyl-CoA | Decenoyl-CoA | Lauroyl-CoA | Dodecenoyl-CoA | Myristoyl-CoA | Myristoyl-CoA | Palmitoyl-CoA | Palmitoleoyl-CoA | Stearoyl-CoA | Oleoyl-CoA | ||
WT_1 | 0.028195996140858656 | 0.048741437530149534 | 0.0015763844669561022 | 5.336878919440424E-4 | 5.275180897250361E-4 | 1.3758658948383984E-4 | 2.1995344910757353E-4 | 0.002631420646406174 | 0.0010180173661360347 | 0.01070460684997588 | 0.0030447973950795946 | 0.06910178485287023 | 0.035476362759286055 | 0.006385745296671489 | 0.0342424023154848 | ||
WT_2 | 0.039968750000000004 | 0.04289329268292683 | 0.0017937195121951219 | 4.451803861788618E-4 | 9.293546747967481E-4 | 5.134197154471545E-4 | 9.423526422764228E-5 | 0.004776753048780488 | 0.0012120604674796748 | 0.010755818089430894 | 0.005491641260162602 | 0.07148882113821138 | 0.033469766260162605 | 0.0072788617886178865 | 0.02866051829268293 | 1.8101265822784811 | |
WT_3 | 0.022494040697674418 | 0.04151792635658915 | 0.0015646681201550387 | 4.3376937984496123E-4 | 4.2757267441860465E-4 | 6.971293604651163E-6 | 5.081298449612404E-4 | 2.010830910852713E-4 | 0.0030983527131782946 | 9.016206395348837E-4 | 0.011990625 | 0.003315237403100775 | 0.05762936046511628 | 0.03439171511627907 | 0.006010804263565892 | 0.0265218992248062 | 0.8414634146341462 |
WT_4 | 0.035885611510791365 | 0.037725899280575535 | 0.0017636091127098319 | 0.001042829736211031 | 4.6313908872901675E-4 | 2.0979280575539565E-5 | 5.796906474820143E-4 | 4.539376498800958E-5 | 0.003251175059952038 | 6.778393285371702E-4 | 0.010244268585131893 | 0.0035885611510791363 | 0.07606522781774579 | 0.035578896882494 | 0.00598093525179856 | 0.030027362110311748 | 0.7989417989417991 |
WT_5 | 0.03836332811684924 | 0.04270005216484089 | 0.002315143453312467 | 6.538445487741261E-4 | 6.204851330203442E-4 | 7.806103286384975E-5 | 5.704460093896713E-4 | 1.1575717266562335E-4 | 0.0035027386541471046 | 0.001611259780907668 | 0.011442279603547207 | 0.003903051643192488 | 0.07405790297339593 | 0.035360980699008865 | 0.004603599374021909 | 0.029222848200312984 | 1.087719298245614 |
KO4_1 | 0.013707720254314259 | 0.010629291553133515 | 6.911943687556767E-4 | 0.0018325363306085376 | 0.02488880563124432 | 3.0203451407811077E-4 | 0.0011123001816530427 | 4.2691416893732965E-4 | 0.0016960399636693913 | 0.00126622161671208 | 0.003020345140781108 | 0.0019080449591280654 | 0.033978882833787465 | 0.02128762488646685 | 0.005082311534968211 | 0.02346575840145322 | 22.375979112271537 |
KO4_2 | 0.025339665032679735 | 0.008777450980392155 | 7.262295751633986E-4 | 0.0016248733660130716 | 0.02549640522875817 | 3.657271241830065E-4 | 0.0010553839869281044 | 2.2178737745098037E-4 | 0.002238772467320261 | 0.001381926062091503 | 0.004153615196078431 | 0.0018704330065359473 | 0.03814011437908496 | 0.015151552287581698 | 0.004284232026143791 | 0.01794675245098039 | 24.158415841584162 |
KO4_3 | 0.007521821071752951 | 0.00789936421435059 | 5.372729336966394E-4 | 0.0014433764759309716 | 0.023843301544050864 | 6.098773841961853E-4 | 0.0015595435967302451 | 2.9913033605812896E-4 | 0.002181037693006358 | 0.0010745458673932788 | 0.00563410535876476 | 0.0017599318801089917 | 0.02962261580381471 | 0.010425999091734786 | 0.0029332198001816526 | 0.01681519073569482 | 15.288640595903168 |
KO4_4 | 0.018517508417508415 | 0.007455450336700335 | 0.0011465782828282826 | 0.0017629313973063971 | 0.023362205387205383 | 7.32087542087542E-4 | 0.0010927483164983164 | 3.848842592592592E-4 | 0.0032028829966329964 | 0.001081982323232323 | 0.0046832070707070695 | 9.823968855218854E-4 | 0.027184132996632995 | 0.013161426767676765 | 0.003687352693602693 | 0.013457491582491581 | 21.379310344827584 |
KO4_5 | 0.004685282776349614 | 0.008740381319622962 | 7.151221079691515E-4 | 0.0020028898886032555 | 0.026878727506426732 | 4.055098543273349E-4 | 0.0013425664095972575 | 3.150921165381319E-4 | 0.0021015274207369316 | 7.014224507283632E-4 | 0.006384040274207368 | 0.0018110946872322191 | 0.028221293916023984 | 0.013507862039417305 | 0.002528956726649528 | 0.016823179091688085 | 20.02040816326531 |
KO9_1 | 0.01051991341991342 | 0.014672510822510825 | 9.096165739022882E-4 | 0.0037294279529993817 | 0.0391135126777984 | 5.022665429808288E-4 | 0.0016610389610389612 | 5.25995670995671E-4 | 0.004113048855905999 | 0.002440145330859617 | 0.005220408163265307 | 0.004152597402597403 | 0.05062213976499692 | 0.026299783549783556 | 0.004587631416202845 | 0.025350618429189863 | 23.547619047619047 |
KO9_2 | 0.015184968979131415 | 0.0011289537507050197 | 0.0031993034404963335 | 0.050857021996615896 | 8.151551043429215E-4 | 0.001987391426959955 | 5.121771009588269E-4 | 0.004328257191201354 | 0.002247086858432036 | 0.005951353637901861 | 0.0036790186125211506 | 0.059874224478285394 | 0.03181269035532995 | 0.005121771009588268 | 0.02492354765933446 | 25.589836660617053 | |
KO9_3 | 0.011312218813905931 | 0.01579133435582822 | 7.519683026584868E-4 | 0.003069992331288344 | 0.04250255623721882 | 7.715848670756647E-4 | 0.002262443762781186 | 5.296472392638037E-4 | 0.004086784253578733 | 0.0018079933537832314 | 0.006211912065439673 | 0.0027267024539877303 | 0.04904141104294479 | 0.029163292433537834 | 0.006538854805725972 | 0.02994795501022495 | 18.78612716763006 |
KO9_4 | 0.011988713534194163 | 0.01666798182687709 | 7.523529411764705E-4 | 0.003058345289335246 | 0.04679268292682926 | 6.391941654710664E-4 | 0.002575126733620277 | 3.009411764705882E-4 | 0.004434600669536107 | 0.001938990913438546 | 0.004923935915829745 | 0.003055286944045911 | 0.04251099952175992 | 0.028412027737924433 | 0.006269607843137254 | 0.02299875657580105 | 18.171021377672208 |
KO9_5 | 0.00992504 | 0.0184176 | 8.08328E-4 | 0.0028615493333333333 | 0.041951199999999994 | 3.444773333333333E-4 | 0.0018656346666666664 | 2.6807839999999996E-4 | 0.003547093333333333 | 0.0028342639999999995 | 0.0067190133333333325 | 0.0035129866666666664 | 0.05184213333333333 | 0.025000186666666667 | 0.005457066666666666 | 0.027421759999999996 | 22.486288848263253 |
KO21_1 | 0.013729378531073446 | 0.013701586266840505 | 0.0013673794002607561 | 0.003390656236418949 | 0.03168318122555411 | 2.945980008691873E-4 | 0.0013229117774880487 | 1.3312494567579313E-4 | 0.004863646240764886 | 0.0012589895697522817 | 0.007170404172099088 | 0.0026430443285528032 | 0.048080617122990006 | 0.02039952194697958 | 0.004613515862668405 | 0.020899782703172536 | 23.949579831932773 |
KO21_2 | 0.006711394302848576 | 0.017865092453773112 | 9.779460269865067E-4 | 0.0034835332333833084 | 0.026653823088455774 | 2.863528235882059E-4 | 0.0020134182908545725 | 3.2598200899550226E-4 | 0.004602098950524738 | 0.0013678460769615192 | 0.00779800099950025 | 0.0023777511244377813 | 0.060722138930534734 | 0.020038305847076464 | 0.004474262868565717 | 0.0255672163918041 | 13.23809523809524 |
KO21_3 | 0.011540870488322719 | 0.019225732484076434 | 0.0011649490445859874 | 0.0026557579617834397 | 0.024439490445859875 | 1.9171422505307858E-4 | 0.0013305944798301488 | 1.7080488322717622E-4 | 0.002457526539278132 | 8.03787685774947E-4 | 0.007277537154989386 | 0.002522698513800425 | 0.04887898089171975 | 0.01778651804670913 | 0.004969363057324841 | 0.024466645435244162 | 18.36734693877551 |
KO21_4 | 0.005767689446768943 | 0.012724593212459317 | 9.543444909344489E-4 | 0.0028719525801952574 | 0.027916806136680607 | 2.1257205950720592E-4 | 0.0020603138075313806 | 2.7916806136680605E-4 | 0.005410925151092514 | 0.0016500348675034865 | 0.009335332403533238 | 0.0034487215248721515 | 0.0600553231055323 | 0.019532845188284513 | 0.005410925151092514 | 0.020157182705718264 | 13.549783549783548 |
KO21_5 | 0.008084667541557304 | 0.014490857392825896 | 9.427449693788277E-4 | 0.0026575896762904634 | 0.02881386701662292 | 2.6995516185476814E-4 | 0.0018435279965004375 | 1.454680664916885E-4 | 0.00388847331583552 | 0.0022631474190726157 | 0.006993657042869641 | 0.003077209098862642 | 0.051473315835520554 | 0.018239457567804023 | 0.003944422572178478 | 0.023498687664041996 | 15.629742033383913 |
Average | |||||||||||||||||
Acyl-CoA chain length | C0 | C2:0 | C4:0 | C6:0 | C8:0 | C8:1 | C10:0 | C10:1 | C12:0 | C12:1 | C14:0 | C14:1 | C16:0 | C16:1 | C18:0 | C18:1 | C8/C10 |
WT | 0.032981545293234736 | 0.042715721603016385 | 0.0018027049330657124 | 6.218623885906045E-4 | 5.936139321379499E-4 | 6.089954913197008E-5 | 5.429215543200201E-4 | 1.35284548414824E-4 | 0.00345208802449282 | 0.001084159516519086 | 0.011027519625617174 | 0.0038686577705229186 | 0.06966861944946792 | 0.03485554434344612 | 0.006051989194935148 | 0.029735006028719736 | 1.0933696174236796 |
KO4 | 0.013954399510520993 | 0.008700387680839913 | 7.632794536826298E-4 | 0.0017333214916924466 | 0.02489388905953709 | 4.83047283774436E-4 | 0.0012325084982813931 | 3.29561651648766E-4 | 0.0022840521082731877 | 0.0011012196640315095 | 0.004775062608107747 | 0.0016663802837054216 | 0.031429407985868824 | 0.014706893014575482 | 0.0037032145563091748 | 0.017701674452461617 | 20.19774232327734 |
KO9 | 0.010936471442003378 | 0.016146879196869513 | 8.702439136884531E-4 | 0.0031837236694905275 | 0.04424339476769247 | 6.145356026407629E-4 | 0.002070327110213409 | 4.2736791753777796E-4 | 0.004101956860711105 | 0.002253696091302686 | 0.005805324623153984 | 0.003425318415963772 | 0.050778181628264064 | 0.02813759614864849 | 0.005594986348264201 | 0.026128527534910063 | 21.370243643832627 |
KO21 | 0.009166800062114197 | 0.015601572361995053 | 0.0010814727864293053 | 0.0030118979376142834 | 0.027901433582634656 | 2.510384541744892E-4 | 0.0017141532704409179 | 2.1090959315139325E-4 | 0.004244534039499158 | 0.00146876112381297 | 0.00771498635459832 | 0.0028138849181051605 | 0.05384207517725946 | 0.01919932971937074 | 0.004682497902365991 | 0.02291790297999621 | 16.277093807053667 |
Replicates vs. mean WT | |||||||||||||||||
Acyl-CoA chain length | C0 | C2:0 | C4:0 | C6:0 | C8:0 | C8:1 | C10:0 | C10:1 | C12:0 | C12:1 | C14:0 | C14:1 | C16:0 | C16:1 | C18:0 | C18:1 | C8/C10 |
WT_1 | 0.8549022154714593 | 1.1410655304651962 | 0.8744550691805533 | 0.8582089892164058 | 0.8886551699100725 | 2.2592382282779795 | 1.6258578801854642 | 0.762269278111117 | 0.9389922337301302 | 0.9707175514889894 | 0.7870423220888922 | 0.9918638462900958 | 1.0178111811917998 | 1.055148165501627 | 1.1515855178375134 | ||
WT_2 | 1.2118519506785663 | 1.0041570427291555 | 0.9950155897918859 | 0.7158824755229583 | 1.5655877068949509 | 0.9456609548136009 | 0.696570786034544 | 1.3837286346376663 | 1.1179724468694798 | 0.975361500554022 | 1.4195210809304302 | 1.0261265646302018 | 0.9602422481304876 | 1.202722204909007 | 0.9638645529448017 | 1.6555486392092222 | |
WT_3 | 0.6820190048004954 | 0.9719589134520754 | 0.8679557544085353 | 0.69753274647798 | 0.7202874650846992 | 0.11447200683775643 | 0.9359176126238817 | 1.48637145513979 | 0.897530043033449 | 0.8316309784649768 | 1.0873365368714023 | 0.8569477063494972 | 0.8271925139397378 | 0.986692813556525 | 0.9931948108229072 | 0.8919419487989968 | 0.7696056312748993 |
WT_4 | 1.0880512478034896 | 0.8831853440563557 | 0.9783126902030531 | 1.6769461465172566 | 0.7802025249996792 | 0.34448991617453856 | 1.06772450434031 | 0.3355428651675604 | 0.9417995824222066 | 0.6252210290174925 | 0.928973054043289 | 0.9275985015842013 | 1.0918147713967183 | 1.0207528688096328 | 0.9882594068085825 | 1.0098320505235356 | 0.7307152002488926 |
WT_5 | 1.1631755812459894 | 0.9996331692972176 | 1.2842608964159723 | 1.0514296422653995 | 1.0452671331105985 | 1.2817998487097257 | 1.050696928222207 | 0.855657013472642 | 1.014672461795561 | 1.4861833119179217 | 1.0376113570422978 | 1.0088903890469796 | 1.0630023037432461 | 1.0145008883115545 | 0.7606754119578761 | 0.9827759298951518 | 0.9948321966441876 |
KO4_1 | 0.4156178897150105 | 0.2488379255749931 | 0.38342068969668774 | 2.9468518505546175 | 41.92759685003554 | 4.959552548141173 | 2.0487309313886763 | 3.1556757511455014 | 0.4913084346736996 | 1.167929255260832 | 0.27389161328398626 | 0.493205931438634 | 0.48772148927729286 | 0.6107385578808083 | 0.8397753814930056 | 0.7891627255359785 | 20.465155383589618 |
KO4_2 | 0.7682982955282412 | 0.2054852558026863 | 0.40285548779653 | 2.612914683095245 | 42.95115705409869 | 6.005415957850054 | 1.9438977482666269 | 1.6394139615332277 | 0.6485270512906984 | 1.274651968677503 | 0.37665906179205433 | 0.4834837086877097 | 0.5474504113971824 | 0.4346956150874356 | 0.7079047711666808 | 0.6035563750566053 | 22.095378778229577 |
KO4_3 | 0.22806151151734688 | 0.18492873157485823 | 0.29803709073061857 | 2.3210544686618775 | 40.16634424023242 | 10.014481106823524 | 2.8725026374822953 | 2.2111197439999093 | 0.6318024562327884 | 0.9911326248773116 | 0.5109132017028206 | 0.4549205395004752 | 0.42519309321610144 | 0.29912024867559367 | 0.48467036303310596 | 0.565501507531351 | 13.983048689360858 |
KO4_4 | 0.5614506007184199 | 0.17453644833601187 | 0.6360321435845804 | 2.8349220497189473 | 39.3558912996945 | 12.02123090437171 | 2.012718610641503 | 2.844997923037639 | 0.9278103495357896 | 0.9979918146235959 | 0.42468363056256775 | 0.25393739735967824 | 0.39019192875423925 | 0.3775992317891172 | 0.6092794575192902 | 0.45258075850038776 | 19.55359834783403 |
KO4_5 | 0.1420577093854566 | 0.20461743338559818 | 0.3966939319087578 | 3.2207927756213497 | 45.279812435703384 | 6.658667594543106 | 2.4728552383202933 | 2.329106466556422 | 0.6087699403452169 | 0.6469734758040239 | 0.5789189673602666 | 0.46814548989879173 | 0.4050789887761945 | 0.38753840440185766 | 0.4178719831102785 | 0.5657701590993227 | 18.310741257324896 |
KO9_1 | 0.31896363030847114 | 0.3434920509800008 | 0.5045842817744876 | 5.997191696143252 | 65.89048969408084 | 8.247459137873271 | 3.059445600975122 | 3.888069089625865 | 1.1914669691860733 | 2.250725371755439 | 0.4733982201344881 | 1.073394869465568 | 0.7266132179024186 | 0.7545365893770268 | 0.758036947594386 | 0.8525513129106083 | 21.536741713295996 |
KO9_2 | 0.3554889958375214 | 0.6262554287157248 | 5.144712880525334 | 85.67356533134272 | 13.385240382920902 | 3.6605498734509725 | 3.7859246082437625 | 1.2538084662071327 | 2.0726533542285033 | 0.5396819810754845 | 0.9509806322371764 | 0.8594145391629785 | 0.9127010050930874 | 0.8462954649480587 | 0.8381887541997436 | 23.404561689682488 | |
KO9_3 | 0.34298631896505843 | 0.3696843635836673 | 0.4171333249638786 | 4.936771201497179 | 71.59966088420857 | 12.669796050601798 | 4.1671651176471975 | 3.915060851145709 | 1.1838586457189668 | 1.66764514468144 | 0.5633099986518512 | 0.7048187293184033 | 0.7039239679281363 | 0.836690201885239 | 1.080447204234647 | 1.0071615583766669 | 17.181863176238647 |
KO9_4 | 0.36349762958660764 | 0.3902071930747876 | 0.4173466923935275 | 4.918041909990267 | 78.82679363387163 | 10.495876809956748 | 4.743091728685342 | 2.224505163352507 | 1.2846140185511745 | 1.7884738213284972 | 0.4465134575132682 | 0.7897537402572918 | 0.6101886309458739 | 0.8151365377619397 | 1.0359582017073377 | 0.7734572696433141 | 16.61928508722312 |
KO9_5 | 0.30092707639250155 | 0.4311667767471224 | 0.448397286307606 | 4.601579683599741 | 70.67084805255372 | 5.656484132367657 | 3.43628771379923 | 1.9815891995144133 | 1.0275211142260694 | 2.614249985186662 | 0.6092950691944283 | 0.9080634357046845 | 0.7441245964538667 | 0.7172513623752212 | 0.9016980187660668 | 0.9222046221720797 | 20.566045086608476 |
KO21_1 | 0.41627456836868265 | 0.3207621398551526 | 0.7585153705300879 | 5.452422109180084 | 53.373378740361595 | 4.837441410785978 | 2.436653632484575 | 0.9840365898076633 | 1.4088998328712812 | 1.1612586068464563 | 0.650228194148218 | 0.6831941426019568 | 0.6901330542061891 | 0.5852590263969094 | 0.7623139622472248 | 0.7028679490761278 | 21.90437657154354 |
KO21_2 | 0.2034893830224879 | 0.41823225227948774 | 0.5424881293930861 | 5.601775082873922 | 44.90093922233229 | 4.702051618931953 | 3.708488408378389 | 2.4096026694485557 | 1.3331348789116921 | 1.2616649636146406 | 0.7071400699560144 | 0.6146191432478105 | 0.8715852188599452 | 0.574895794185015 | 0.7393045037671556 | 0.8598355879635554 | 12.107612125978338 |
KO21_3 | 0.34991903459083873 | 0.45008563036235355 | 0.6462228084131628 | 4.2706521740323895 | 41.17068202533424 | 3.1480401379923433 | 2.4508042998894126 | 1.2625601757817602 | 0.7118956764259194 | 0.7413924551948502 | 0.6599432512533013 | 0.652086243715333 | 0.7015925000088838 | 0.5102923618535748 | 0.8211123479010263 | 0.8228229518976019 | 16.798845190206325 |
KO21_4 | 0.1748762647562189 | 0.2978901616298755 | 0.5293958392355833 | 4.618308862036633 | 47.02855614614015 | 3.49053585021721 | 3.794864637694873 | 2.0635620596580697 | 1.5674354514431845 | 1.5219484239747836 | 0.8465487000219934 | 0.8914516944738679 | 0.8620139681265201 | 0.5603942086176964 | 0.8940738287538361 | 0.6778940177866225 | 12.392683438296986 |
KO21_5 | 0.24512700874618065 | 0.33923943805745327 | 0.5229613299918022 | 4.273597704330781 | 48.53974183666374 | 4.432794096221828 | 3.3955697316334335 | 1.0752748055575327 | 1.126411982616467 | 2.0874671896428203 | 0.6342003714618852 | 0.7954203450895326 | 0.7388307137743013 | 0.5232871243691704 | 0.6517563804442228 | 0.7902701496460315 | 14.295021358113523 |
Mean Clone vs. mean WT (for WT, this should be 1 everywhere) | |||||||||||||||||
Acyl-CoA chain length | C0 | C2:0 | C4:0 | C6:0 | C8:0 | C8:1 | C10:0 | C10:1 | C12:0 | C12:1 | C14:0 | C14:1 | C16:0 | C16:1 | C18:0 | C18:1 | C8/C10 |
WT | 1 | 1.0000000000000002 | 1 | 1 | 1 | 1 | 0.9999999999999999 | 1 | 1 | 1.0000000000000004 | 1.0000000000000002 | 1.0000000000000002 | 1 | 1 | 1 | 1 | 1 |
KO4 | 0.4230972013728951 | 0.20368115893482952 | 0.4234078687434349 | 2.7873071655304074 | 41.9361603759529 | 7.931869622345912 | 2.270141033219879 | 2.43606276925454 | 0.6616436464156386 | 1.0157358278486532 | 0.433013294940339 | 0.4307386133770577 | 0.4511271822842021 | 0.4219384115669625 | 0.6119003912644723 | 0.595314305144729 | 18.472931752822554 |
KO9 | 0.3315936638131597 | 0.3780078760446199 | 0.48274340283104494 | 5.119659474351154 | 74.53227151921149 | 10.090971302744077 | 3.813308006911573 | 3.1590297823764515 | 1.1882538427778833 | 2.0787495354361085 | 0.526439745313904 | 0.8854022813966248 | 0.7288529904786548 | 0.8072631392985029 | 0.9244871674500992 | 0.8787127034604824 | 19.54530590870779 |
KO21 | 0.2779372518968818 | 0.36524192443686454 | 0.5999166955127445 | 4.843351186490762 | 47.0026595941664 | 4.122172622829862 | 3.1572761420161366 | 1.5590072600507163 | 1.2295555644537088 | 1.3547463278547103 | 0.6996121173682825 | 0.7273543138257001 | 0.7728310909951679 | 0.5508257030844732 | 0.7737122046226931 | 0.7707381312739879 | 14.887091746163195 |
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area ratio / mg protein | |||||||||||||||||
Acyl-CoA chain length | C0 | C2:0 | C4:0 | C6:0 | C8:0 | C8:1 | C10:0 | C10:1 | C12:0 | C12:1 | C14:0 | C14:1 | C16:0 | C16:1 | C18:0 | C18:1 | C8/C10 |
CoA | Acetyl-CoA | Butyryl-CoA | Hexanoyl-CoA | Octanoyl-CoA | Octenoyl-CoA | Decanoyl-CoA | Decenoyl-CoA | Lauroyl-CoA | Dodecenoyl-CoA | Myristoyl-CoA | Myristoyl-CoA | Palmitoyl-CoA | Palmitoleoyl-CoA | Stearoyl-CoA | Oleoyl-CoA | ||
WT_1 | 0.012833188615533042 | 0.02085393150024119 | 0.001098224794983116 | 2.504939700916546E-4 | 6.354896285576459E-4 | 3.8869753979739506E-5 | 2.3630342498794E-4 | 4.1646164978292326E-5 | 0.0019311480945489626 | 5.336878919440424E-4 | 0.007959044862518088 | 0.0028257694163048718 | 0.0684848046309696 | 0.03146599131693198 | 0.00706442354076218 | 0.025049397009165458 | 2.6892950391644925 |
WT_2 | 0.017482266260162603 | 0.026450863821138215 | 0.001296547256097561 | 6.466488821138212E-4 | 7.278861788617886E-4 | 3.0740193089430896E-4 | 2.651585365853659E-5 | 0.007636305894308943 | 0.0031715040650406503 | 0.016669893292682928 | 0.005654115853658537 | 0.1319293699186992 | 0.09553506097560975 | 0.012802997967479674 | 0.03931885162601626 | 2.3678646934460885 | |
WT_3 | 0.016762088178294575 | 0.02450796996124031 | 8.117684108527132E-4 | 3.408187984496124E-4 | 5.608018410852713E-4 | 1.4996027131782945E-5 | 4.058842054263566E-4 | 6.7234253875969E-5 | 0.002599517926356589 | 7.77686531007752E-4 | 0.010751283914728684 | 0.002695566860465116 | 0.07312112403100775 | 0.035011385658914734 | 0.00536015019379845 | 0.029961070736434108 | 1.381679389312977 |
WT_4 | 0.011409784172661868 | 0.02248218225419664 | 0.0011195083932853715 | 4.1713189448441243E-4 | 6.993093525179855E-4 | 2.9045875299760187E-5 | 5.428848920863309E-4 | 1.453827338129496E-4 | 0.0015949160671462827 | 7.361151079136689E-4 | 0.00874136690647482 | 0.002128599520383693 | 0.0726913669064748 | 0.028125731414868103 | 0.004079304556354915 | 0.019200335731414865 | 1.2881355932203389 |
WT_5 | 0.010541575378195096 | 0.025653390714658317 | 0.0015078455920709438 | 3.2058398539384453E-4 | 6.138132498695879E-4 | 7.872822117892539E-5 | 3.12244131455399E-4 | 7.739384454877412E-5 | 0.0030957537819509646 | 9.540792905581637E-4 | 0.01647955138236828 | 0.0037696139801773596 | 0.08973682837767344 | 0.06972117892540426 | 0.0035027386541471046 | 0.02521971830985915 | 1.965811965811966 |
KO4_1 | 0.019080449591280652 | 0.014027179836512261 | 7.02811080835604E-4 | 0.002584718437783833 | 0.03136512261580381 | 3.7173478655767487E-4 | 0.0010774500454132606 | 3.4559718437783836E-4 | 0.0031365122615803816 | 0.0017134650317892823 | 0.00473381017257039 | 0.0018296321525885558 | 0.05808356039963669 | 0.02334959128065395 | 0.006127815622161671 | 0.03049386920980926 | 29.110512129380055 |
KO4_2 | 0.016118116830065355 | 0.009979125816993463 | 0.0010423223039215683 | 0.002058521241830065 | 0.03396037581699346 | 4.493218954248365E-4 | 0.0014524591503267971 | 1.4054370915032676E-4 | 0.005407536764705881 | 0.0023641646241830063 | 0.007053308823529411 | 0.0025888255718954246 | 0.051724264705882345 | 0.031086805555555548 | 0.0047283292483660125 | 0.02476495098039215 | 23.38129496402878 |
KO4_3 | 0.010542166212534058 | 0.010513124432334242 | 7.579904632152587E-4 | 0.002668939600363306 | 0.03020345140781108 | 4.03680744777475E-4 | 0.0018819073569482287 | 4.03680744777475E-4 | 0.00270669391462307 | 0.001617627157129882 | 0.006127815622161671 | 0.0016379564032697547 | 0.050823115349682105 | 0.018180154405086284 | 0.005169436875567666 | 0.02401755222524977 | 16.049382716049383 |
KO4_4 | 0.007993749999999999 | 0.010604503367003365 | 9.36641414141414E-4 | 0.0025596148989898986 | 0.031221380471380466 | 4.4409722222222214E-4 | 0.0016794949494949492 | 3.2567129629629623E-4 | 0.00357969276094276 | 9.608648989898988E-4 | 0.006782575757575756 | 0.002597295875420875 | 0.04548632154882155 | 0.01781771885521885 | 0.003552777777777777 | 0.019621022727272727 | 18.58974358974359 |
KO4_5 | 0.028769280205655518 | 0.011096722365038558 | 0.0013288667523564694 | 0.002904327335047129 | 0.025673157669237355 | 6.630634104541558E-4 | 0.0018549335904027417 | 3.0961225364181655E-4 | 0.0046030848329048826 | 0.0014768230505569832 | 0.0059730505569837175 | 0.0018384940017137955 | 0.05260668380462724 | 0.01701497429305912 | 0.005178470437017994 | 0.024494987146529555 | 13.840472673559823 |
KO9_1 | 0.009768491032776747 | 0.01597761286332715 | 6.28821892393321E-4 | 0.0030333735312306743 | 0.03820389610389611 | 4.785374149659864E-4 | 0.0021277118119975265 | 3.598917748917749E-4 | 0.005536796536796538 | 0.002740714285714286 | 0.00783061224489796 | 0.003678014842300557 | 0.07435126777983922 | 0.041921459492888065 | 0.005932282003710576 | 0.026378880643166357 | 17.955390334572492 |
KO9_2 | 0.006348110547095318 | 0.016339170896785108 | 6.023491257755217E-4 | 0.0026546644106034967 | 0.02881897913141568 | 3.437357586012408E-4 | 0.00192968133107727 | 3.267834179357022E-4 | 0.003159627749576988 | 9.305752961082909E-4 | 0.006456316976875352 | 0.001229946418499718 | 0.07141624365482234 | 0.03426536943034405 | 0.006131697687535251 | 0.024598928369994357 | 14.934579439252337 |
KO9_3 | 0.04544504089979551 | 0.015268225971370144 | 0.0014450869120654398 | 0.0029130598159509205 | 0.03727147239263804 | 6.342689161554193E-4 | 0.0016870245398773007 | 6.473466257668712E-4 | 0.0041194785276073625 | 0.0010592944785276074 | 0.006669631901840492 | 0.0028738266871165645 | 0.05754192229038855 | 0.029849872188139063 | 0.0056561094069529656 | 0.026482361963190187 | 22.093023255813954 |
KO9_4 | 0.00834928263988522 | 0.013548469631755138 | 6.239024390243902E-4 | 0.0018931157340985173 | 0.026454686752749874 | 4.893352462936394E-4 | 0.0015261142993782876 | 2.80450263032042E-4 | 0.0030889287422285984 | 8.624533715925393E-4 | 0.0055967718794835 | 0.003058345289335246 | 0.054744380679100896 | 0.025323098995695834 | 0.004618101386896221 | 0.02027682926829268 | 17.334669338677354 |
KO9_5 | 0.010436639999999999 | 0.015416213333333331 | 6.991866666666667E-4 | 0.0026296239999999997 | 0.034004346666666664 | 7.503466666666667E-4 | 0.0021964693333333335 | 3.1378133333333333E-4 | 0.00347888 | 0.0018519919999999998 | 0.006412053333333333 | 0.0028240319999999993 | 0.06377946666666666 | 0.030491359999999995 | 0.0062415199999999995 | 0.0276264 | 15.481366459627326 |
KO21_1 | 0.009004693611473272 | 0.013979508909169927 | 9.616123424598001E-4 | 0.002807018687527162 | 0.02729200347674924 | 2.284524119947849E-4 | 0.0019537961755758367 | 3.0015645371577577E-4 | 0.0034184485006518908 | 0.0016703150803998262 | 0.007003650586701435 | 0.0019510169491525424 | 0.06086505867014342 | 0.015647044763146458 | 0.00555845284658844 | 0.02162238157322903 | 13.968705547652915 |
KO21_2 | 0.01278360819590205 | 0.016394977511244378 | 0.0013998050974512745 | 0.003707246376811594 | 0.030808495752123938 | 3.291779110444778E-4 | 0.0013806296851574212 | 2.476824087956022E-4 | 0.002863528235882059 | 6.040254872563718E-4 | 0.0075423288355822085 | 0.002364967516241879 | 0.06551599200399799 | 0.013870214892553724 | 0.0068392303848075955 | 0.018983658170914543 | 22.314814814814817 |
KO21_3 | 0.00847235668789809 | 0.0130343949044586 | 8.608131634819534E-4 | 0.0024629575371549898 | 0.02169683651804671 | 2.0773566878980892E-4 | 0.0013523184713375798 | 1.6184373673036094E-4 | 0.004534883227176221 | 0.0012980084925690023 | 0.008309426751592358 | 0.0024032165605095543 | 0.06462887473460723 | 0.016863248407643316 | 0.00477927813163482 | 0.018383927813163482 | 16.044176706827308 |
KO21_4 | 0.006510948396094838 | 0.015400325430032539 | 9.454253835425382E-4 | 0.0026370827522082746 | 0.021970734542073447 | 3.478451882845188E-4 | 0.00197706880520688 | 2.880871687587168E-4 | 0.005767689446768943 | 0.0012843514644351461 | 0.009127219897721988 | 0.0028035727568572746 | 0.05410925151092514 | 0.017035495118549508 | 0.0038649465364946527 | 0.018878777312877727 | 11.112781954887216 |
area ratio / mg protein - OUTLIERS EXCLUDED | |||||||||||||||||
Acyl-CoA chain length | C0 | C2:0 | C4:0 | C6:0 | C8:0 | C8:1 | C10:0 | C10:1 | C12:0 | C12:1 | C14:0 | C14:1 | C16:0 | C16:1 | C18:0 | C18:1 | C8/C10 |
CoA | Acetyl-CoA | Butyryl-CoA | Hexanoyl-CoA | Octanoyl-CoA | Octenoyl-CoA | Decanoyl-CoA | Decenoyl-CoA | Lauroyl-CoA | Dodecenoyl-CoA | Myristoyl-CoA | Myristoyl-CoA | Palmitoyl-CoA | Palmitoleoyl-CoA | Stearoyl-CoA | Oleoyl-CoA | ||
WT_1 | 0.012833188615533042 | 0.02085393150024119 | 0.001098224794983116 | 2.504939700916546E-4 | 6.354896285576459E-4 | 3.8869753979739506E-5 | 2.3630342498794E-4 | 4.1646164978292326E-5 | 0.0019311480945489626 | 5.336878919440424E-4 | 0.007959044862518088 | 0.0028257694163048718 | 0.0684848046309696 | 0.03146599131693198 | 0.00706442354076218 | 0.025049397009165458 | 2.6892950391644925 |
WT_2 | 0.017482266260162603 | 0.026450863821138215 | 0.001296547256097561 | 6.466488821138212E-4 | 7.278861788617886E-4 | 3.0740193089430896E-4 | 2.651585365853659E-5 | 0.007636305894308943 | 0.0031715040650406503 | 0.016669893292682928 | 0.005654115853658537 | 0.1319293699186992 | 0.09553506097560975 | 0.012802997967479674 | 0.03931885162601626 | 2.3678646934460885 | |
WT_3 | 0.016762088178294575 | 0.02450796996124031 | 8.117684108527132E-4 | 3.408187984496124E-4 | 5.608018410852713E-4 | 1.4996027131782945E-5 | 4.058842054263566E-4 | 6.7234253875969E-5 | 0.002599517926356589 | 7.77686531007752E-4 | 0.010751283914728684 | 0.002695566860465116 | 0.07312112403100775 | 0.035011385658914734 | 0.00536015019379845 | 0.029961070736434108 | 1.381679389312977 |
WT_4 | 0.011409784172661868 | 0.02248218225419664 | 0.0011195083932853715 | 4.1713189448441243E-4 | 6.993093525179855E-4 | 2.9045875299760187E-5 | 5.428848920863309E-4 | 1.453827338129496E-4 | 0.0015949160671462827 | 7.361151079136689E-4 | 0.00874136690647482 | 0.002128599520383693 | 0.0726913669064748 | 0.028125731414868103 | 0.004079304556354915 | 0.019200335731414865 | 1.2881355932203389 |
WT_5 | 0.010541575378195096 | 0.025653390714658317 | 0.0015078455920709438 | 3.2058398539384453E-4 | 6.138132498695879E-4 | 7.872822117892539E-5 | 3.12244131455399E-4 | 7.739384454877412E-5 | 0.0030957537819509646 | 9.540792905581637E-4 | 0.01647955138236828 | 0.0037696139801773596 | 0.08973682837767344 | 0.06972117892540426 | 0.0035027386541471046 | 0.02521971830985915 | 1.965811965811966 |
KO4_1 | 0.019080449591280652 | 0.014027179836512261 | 7.02811080835604E-4 | 0.002584718437783833 | 0.03136512261580381 | 3.7173478655767487E-4 | 0.0010774500454132606 | 3.4559718437783836E-4 | 0.0031365122615803816 | 0.0017134650317892823 | 0.00473381017257039 | 0.0018296321525885558 | 0.05808356039963669 | 0.02334959128065395 | 0.006127815622161671 | 0.03049386920980926 | 29.110512129380055 |
KO4_2 | 0.016118116830065355 | 0.009979125816993463 | 0.0010423223039215683 | 0.002058521241830065 | 0.03396037581699346 | 4.493218954248365E-4 | 0.0014524591503267971 | 1.4054370915032676E-4 | 0.005407536764705881 | 0.0023641646241830063 | 0.007053308823529411 | 0.0025888255718954246 | 0.051724264705882345 | 0.031086805555555548 | 0.0047283292483660125 | 0.02476495098039215 | 23.38129496402878 |
KO4_3 | 0.010542166212534058 | 0.010513124432334242 | 7.579904632152587E-4 | 0.002668939600363306 | 0.03020345140781108 | 4.03680744777475E-4 | 0.0018819073569482287 | 4.03680744777475E-4 | 0.00270669391462307 | 0.001617627157129882 | 0.006127815622161671 | 0.0016379564032697547 | 0.050823115349682105 | 0.018180154405086284 | 0.005169436875567666 | 0.02401755222524977 | 16.049382716049383 |
KO4_4 | 0.007993749999999999 | 0.010604503367003365 | 9.36641414141414E-4 | 0.0025596148989898986 | 0.031221380471380466 | 4.4409722222222214E-4 | 0.0016794949494949492 | 3.2567129629629623E-4 | 0.00357969276094276 | 9.608648989898988E-4 | 0.006782575757575756 | 0.002597295875420875 | 0.04548632154882155 | 0.01781771885521885 | 0.003552777777777777 | 0.019621022727272727 | 18.58974358974359 |
KO4_5 | 0.028769280205655518 | 0.011096722365038558 | 0.0013288667523564694 | 0.002904327335047129 | 0.025673157669237355 | 6.630634104541558E-4 | 0.0018549335904027417 | 3.0961225364181655E-4 | 0.0046030848329048826 | 0.0014768230505569832 | 0.0059730505569837175 | 0.0018384940017137955 | 0.05260668380462724 | 0.01701497429305912 | 0.005178470437017994 | 0.024494987146529555 | 13.840472673559823 |
KO9_1 | 0.009768491032776747 | 0.01597761286332715 | 6.28821892393321E-4 | 0.0030333735312306743 | 0.03820389610389611 | 4.785374149659864E-4 | 0.0021277118119975265 | 3.598917748917749E-4 | 0.005536796536796538 | 0.002740714285714286 | 0.00783061224489796 | 0.003678014842300557 | 0.07435126777983922 | 0.041921459492888065 | 0.005932282003710576 | 0.026378880643166357 | 17.955390334572492 |
KO9_2 | 0.006348110547095318 | 0.016339170896785108 | 6.023491257755217E-4 | 0.0026546644106034967 | 0.02881897913141568 | 3.437357586012408E-4 | 0.00192968133107727 | 3.267834179357022E-4 | 0.003159627749576988 | 9.305752961082909E-4 | 0.006456316976875352 | 0.001229946418499718 | 0.07141624365482234 | 0.03426536943034405 | 0.006131697687535251 | 0.024598928369994357 | 14.934579439252337 |
KO9_3 | 0.015268225971370144 | 0.0014450869120654398 | 0.0029130598159509205 | 0.03727147239263804 | 6.342689161554193E-4 | 0.0016870245398773007 | 6.473466257668712E-4 | 0.0041194785276073625 | 0.0010592944785276074 | 0.006669631901840492 | 0.0028738266871165645 | 0.05754192229038855 | 0.029849872188139063 | 0.0056561094069529656 | 0.026482361963190187 | 22.093023255813954 | |
KO9_4 | 0.00834928263988522 | 0.013548469631755138 | 6.239024390243902E-4 | 0.0018931157340985173 | 0.026454686752749874 | 4.893352462936394E-4 | 0.0015261142993782876 | 2.80450263032042E-4 | 0.0030889287422285984 | 8.624533715925393E-4 | 0.0055967718794835 | 0.003058345289335246 | 0.054744380679100896 | 0.025323098995695834 | 0.004618101386896221 | 0.02027682926829268 | 17.334669338677354 |
KO9_5 | 0.010436639999999999 | 0.015416213333333331 | 6.991866666666667E-4 | 0.0026296239999999997 | 0.034004346666666664 | 7.503466666666667E-4 | 0.0021964693333333335 | 3.1378133333333333E-4 | 0.00347888 | 0.0018519919999999998 | 0.006412053333333333 | 0.0028240319999999993 | 0.06377946666666666 | 0.030491359999999995 | 0.0062415199999999995 | 0.0276264 | 15.481366459627326 |
KO21_1 | 0.009004693611473272 | 0.013979508909169927 | 9.616123424598001E-4 | 0.002807018687527162 | 0.02729200347674924 | 2.284524119947849E-4 | 0.0019537961755758367 | 3.0015645371577577E-4 | 0.0034184485006518908 | 0.0016703150803998262 | 0.007003650586701435 | 0.0019510169491525424 | 0.06086505867014342 | 0.015647044763146458 | 0.00555845284658844 | 0.02162238157322903 | 13.968705547652915 |
KO21_2 | 0.01278360819590205 | 0.016394977511244378 | 0.0013998050974512745 | 0.003707246376811594 | 0.030808495752123938 | 3.291779110444778E-4 | 0.0013806296851574212 | 2.476824087956022E-4 | 0.002863528235882059 | 6.040254872563718E-4 | 0.0075423288355822085 | 0.002364967516241879 | 0.06551599200399799 | 0.013870214892553724 | 0.0068392303848075955 | 0.018983658170914543 | 22.314814814814817 |
KO21_3 | 0.00847235668789809 | 0.0130343949044586 | 8.608131634819534E-4 | 0.0024629575371549898 | 0.02169683651804671 | 2.0773566878980892E-4 | 0.0013523184713375798 | 1.6184373673036094E-4 | 0.004534883227176221 | 0.0012980084925690023 | 0.008309426751592358 | 0.0024032165605095543 | 0.06462887473460723 | 0.016863248407643316 | 0.00477927813163482 | 0.018383927813163482 | 16.044176706827308 |
KO21_4 | 0.006510948396094838 | 0.015400325430032539 | 9.454253835425382E-4 | 0.0026370827522082746 | 0.021970734542073447 | 3.478451882845188E-4 | 0.00197706880520688 | 2.880871687587168E-4 | 0.005767689446768943 | 0.0012843514644351461 | 0.009127219897721988 | 0.0028035727568572746 | 0.05410925151092514 | 0.017035495118549508 | 0.0038649465364946527 | 0.018878777312877727 | 11.112781954887216 |
Average | |||||||||||||||||
Acyl-CoA chain length | C0 | C2:0 | C4:0 | C6:0 | C8:0 | C8:1 | C10:0 | C10:1 | C12:0 | C12:1 | C14:0 | C14:1 | C16:0 | C16:1 | C18:0 | C18:1 | C8/C10 |
WT | 0.013805780520969438 | 0.023989667650294935 | 0.001166778889457941 | 3.95135506106669E-4 | 6.474600501784559E-4 | 4.0409969397552E-5 | 3.609437169700671E-4 | 7.163457017490433E-5 | 0.0033715283528623482 | 0.0012346145772928556 | 0.012120228071754561 | 0.0034147331261979155 | 0.08719269877296495 | 0.05197186965834576 | 0.006561922982508466 | 0.027749874682577964 | 1.7937978131702719 |
KO4 | 0.016500752567907118 | 0.011244131163576377 | 9.537264028940627E-4 | 0.002555224302802846 | 0.030484697596245235 | 4.663796118872728E-4 | 0.0015892490185171952 | 3.0502103764875065E-4 | 0.0038867041069513956 | 0.0016265889525298107 | 0.006134112186564189 | 0.002098440800977681 | 0.05174478916172999 | 0.021489848877914754 | 0.004951365992178223 | 0.024678476457850696 | 19.181825655420656 |
KO9 | 0.008725631054939322 | 0.015309938539314175 | 7.998694071850679E-4 | 0.002624767498376722 | 0.03295067620947327 | 5.392448005365905E-4 | 0.0018934002631327434 | 3.8565068299194476E-4 | 0.003876742311241898 | 0.0014890058863885447 | 0.006593077267286128 | 0.0027328330474504165 | 0.06436665621416353 | 0.0323702320214134 | 0.005715942097019003 | 0.025072680048928715 | 17.402910969788508 |
KO21 | 0.009192901722842062 | 0.01470230168872636 | 0.0010419139967338916 | 0.0029035763384255052 | 0.025442017572248333 | 2.7830279502839763E-4 | 0.0016659532843194295 | 2.494424420001139E-4 | 0.004146137352619779 | 0.0012141751311650867 | 0.007995656517899496 | 0.0023806934456903125 | 0.06127979422991844 | 0.01585400079547325 | 0.005260476974881377 | 0.019467186217546197 | 15.271747300310304 |
Replicates vs. mean WT | |||||||||||||||||
Acyl-CoA chain length | C0 | C2:0 | C4:0 | C6:0 | C8:0 | C8:1 | C10:0 | C10:1 | C12:0 | C12:1 | C14:0 | C14:1 | C16:0 | C16:1 | C18:0 | C18:1 | C8/C10 |
WT_1 | 0.9295518349028411 | 0.8692880536835952 | 0.9412449992931621 | 0.6339444727703928 | 0.9815117216614204 | 0.9618852614645682 | 0.6546821952507808 | 0.5813696498297994 | 0.5727812114969946 | 0.43227084934819254 | 0.6566745126740765 | 0.8275227702643876 | 0.7854419646912462 | 0.6054427428488538 | 1.0765782468939646 | 0.9026850497776147 | 1.4992185961089797 |
WT_2 | 1.266300462593114 | 1.1025940086674364 | 1.1112193302536588 | 1.6365243622000771 | 1.1242179014151765 | 0.8516616758833945 | 0.37015443233336887 | 2.264938952041112 | 2.5688211717010665 | 1.3753778554325293 | 1.6558002176744129 | 1.5130781794267083 | 1.838207122499941 | 1.9511045773636002 | 1.4169019527393245 | 1.3200287546684197 | |
WT_3 | 1.2141354958406616 | 1.0216052309894756 | 0.6957345716375126 | 0.8625365050277373 | 0.8661566700998781 | 0.37109721574526583 | 1.124508299613971 | 0.938572726992129 | 0.7710206334612786 | 0.6299022750184826 | 0.8870529375419827 | 0.7893931270308246 | 0.8386152173291802 | 0.6736603067981514 | 0.8168566147585891 | 1.0796831005238516 | 0.7702536925669808 |
WT_4 | 0.8264497726391986 | 0.9371610554146312 | 0.9594863289011595 | 1.0556679620985652 | 1.080081083497335 | 0.7187799380397393 | 1.50407076383976 | 2.0295052159590035 | 0.4730543243963043 | 0.5962306953541334 | 0.7212213214738122 | 0.6233575045888727 | 0.8336863972492793 | 0.5411722071913495 | 0.6216629739831989 | 0.6919071149344431 | 0.7181052311262159 |
WT_5 | 0.7635624340241843 | 1.069351651244861 | 1.2923147699145077 | 0.811326697903228 | 0.9480326233261895 | 1.9482375847504272 | 0.8650770654120938 | 1.0803979748856989 | 0.9182048786043109 | 0.7727750085781242 | 1.359673372877599 | 1.103926380441502 | 1.0291782413035864 | 1.341517620661705 | 0.5337975870006465 | 0.908822782024767 | 1.0958938356255907 |
KO4_1 | 1.3820623587561442 | 0.5847175559491258 | 0.6023515570821769 | 6.541346950193015 | 48.44333269235502 | 9.199086069592376 | 2.9850915662361093 | 4.8244469609299205 | 0.9302939003664485 | 1.3878542043026934 | 0.39057104738831117 | 0.535805313320556 | 0.6661516527992379 | 0.4492736442646801 | 0.933844490174 | 1.0988831322165948 | 16.228424360676158 |
KO4_2 | 1.1674904439907425 | 0.4159759927674853 | 0.8933331870666666 | 5.2096589904384745 | 52.45169305447208 | 11.119085268400525 | 4.02405993521491 | 1.9619536881030004 | 1.6038829274904391 | 1.91490094776535 | 0.5819452226288306 | 0.7581340843399714 | 0.5932178431655566 | 0.5981467620833141 | 0.7205706712757677 | 0.8924346961444183 | 13.034520831924644 |
KO4_3 | 0.7636052301803354 | 0.43823551812336137 | 0.6496436214811908 | 6.754491963176832 | 46.64913518523076 | 9.98963252869797 | 5.213852654773582 | 5.635278382934949 | 0.8028091806866019 | 1.3102284606722039 | 0.5055858343492863 | 0.47967332811554536 | 0.5828826961993332 | 0.3498075886936439 | 0.7877929822320947 | 0.8655012860410706 | 8.947152571049509 |
KO4_4 | 0.5790147096615353 | 0.4420446136056825 | 0.8027582797427509 | 6.477815482111892 | 48.221323404857316 | 10.989793579233076 | 4.653066033655959 | 4.546286736992084 | 1.061741853039345 | 0.778271143612115 | 0.5596079312551987 | 0.7606146013269259 | 0.5216758075955447 | 0.3428339017308692 | 0.5414232668149415 | 0.707067075138587 | 10.363343880372435 |
KO4_5 | 2.083857566905268 | 0.4625625718037879 | 1.1389190911517355 | 7.35020591711414 | 39.65211083241538 | 16.40841159593463 | 5.1391214286092435 | 4.322106671204439 | 1.3652813653478464 | 1.1961814461928832 | 0.4928166798200391 | 0.5384004939094141 | 0.6033381756149807 | 0.32738815064596816 | 0.7891696459744776 | 0.8827062257657003 | 7.715737287637139 |
KO9_1 | 0.7075652852759394 | 0.6660206008785919 | 0.538938352480355 | 7.676793111099964 | 59.00579671806187 | 11.842063285377685 | 5.894857596798054 | 5.023995732968821 | 1.6422215557214366 | 2.219894642523873 | 0.646077961449151 | 1.0771016962007185 | 0.8527235516982603 | 0.8066182680837272 | 0.9040462711195685 | 0.9505945862785338 | 10.009706892684298 |
KO9_2 | 0.45981540395005177 | 0.6810920073994535 | 0.5162495921188285 | 6.718364635869638 | 44.510822132535374 | 8.506211801834821 | 5.346211169087333 | 4.561811666320068 | 0.9371499862649941 | 0.7537374928366447 | 0.5326893964909288 | 0.36018815323034736 | 0.8190621997006672 | 0.6593060756828408 | 0.934436095010559 | 0.8864518723552346 | 8.325676020787249 |
KO9_3 | 0.6364500831749719 | 1.2385267895417567 | 7.372305882237077 | 57.565671244681596 | 15.695852424818781 | 4.67392687712917 | 9.036790814634573 | 1.2218430623933572 | 0.8579960888282452 | 0.5502893066330703 | 0.8415962773396539 | 0.6599396864663862 | 0.5743467068698327 | 0.8619591272299223 | 0.9543236596962525 | 12.31633971989731 | |
KO9_4 | 0.6047671572935405 | 0.5647627065641557 | 0.5347220837310839 | 4.7910544733164535 | 40.85918003042553 | 12.109270400073177 | 4.228122634158077 | 3.9150128540911084 | 0.9161805623275184 | 0.6985608200768569 | 0.46177116852499084 | 0.8956323016494456 | 0.6278551008226733 | 0.48724625768065655 | 0.7037725677680587 | 0.7306998500077176 | 9.66366956822235 |
KO9_5 | 0.7559616049341006 | 0.6426188790132655 | 0.5992452151679681 | 6.654992931184772 | 52.51960589274076 | 18.56835523147221 | 6.0853513444465515 | 4.380305941212446 | 1.0318406478908928 | 1.5000568064414646 | 0.5290373494106291 | 0.8270139702379542 | 0.7314771484793424 | 0.5866896881032955 | 0.9511723951404891 | 0.9955504417951305 | 8.630496896562889 |
KO21_1 | 0.6522408202706214 | 0.5827304118153575 | 0.8241598739471053 | 7.103939393311296 | 42.1524130627471 | 5.653367607069367 | 5.413021708694445 | 4.190106159399129 | 1.013916581110673 | 1.3529040650583706 | 0.5778480854682106 | 0.5713526876183362 | 0.6980522397709669 | 0.3010675749402027 | 0.8470768190064275 | 0.779188440328492 | 7.787224092421708 |
KO21_2 | 0.9259605551808663 | 0.6834182844981104 | 1.199717538686008 | 9.382215264175228 | 47.583624261655004 | 8.145957939389557 | 3.8250553209433376 | 3.457582116998205 | 0.8493264585632183 | 0.4892421476027125 | 0.6222926491919024 | 0.6925775540401066 | 0.7513930974265467 | 0.2668792749565132 | 1.042260081844655 | 0.6840988792945051 | 12.439983286286145 |
KO21_3 | 0.6136818324056019 | 0.543333700760892 | 0.7377688877126221 | 6.233197217387244 | 33.51069538895339 | 5.140703442413232 | 3.746618676977073 | 2.259296542649732 | 1.3450526742052198 | 1.051347130061554 | 0.6855833654613284 | 0.7037787351731878 | 0.7412188823618121 | 0.324468765863138 | 0.7283349933204819 | 0.6624868769121092 | 8.944250343616822 |
KO21_4 | 0.4716103074509576 | 0.6419565979207387 | 0.8102866722089576 | 6.6738693725397065 | 33.933730020899006 | 8.607905263734025 | 5.47749887933591 | 4.021622075142179 | 1.7107047140423157 | 1.0402853554923583 | 0.7530567777839434 | 0.8210225084204081 | 0.6205708995407572 | 0.3277829955038747 | 0.5889960224765053 | 0.6803193718467592 | 6.195114005210554 |
Mean Clone vs. mean WT (for WT, this should be 1 everywhere) | |||||||||||||||||
Acyl-CoA chain length | C0 | C2:0 | C4:0 | C6:0 | C8:0 | C8:1 | C10:0 | C10:1 | C12:0 | C12:1 | C14:0 | C14:1 | C16:0 | C16:1 | C18:0 | C18:1 | C8/C10 |
WT | 1 | 1 | 1.0000000000000002 | 1 | 0.9999999999999998 | 1.0000000000000002 | 1 | 1 | 1 | 0.9999999999999998 | 1 | 1 | 1 | 1.0000000000000002 | 0.9999999999999998 | 1 | 0.9999999999999998 |
KO4 | 1.1952060618988052 | 0.4687072504498886 | 0.8174011473049042 | 6.466703860606872 | 47.08351903386612 | 11.541201808371714 | 4.40303832369796 | 4.258014488032879 | 1.1528018453861362 | 1.3174872405090494 | 0.5061053430883333 | 0.6145255642024826 | 0.5934532350749306 | 0.4134900094836951 | 0.7545602112942562 | 0.8893184830612741 | 10.693415676273808 |
KO9 | 0.6320273628634081 | 0.6381888554060876 | 0.6855364066079984 | 6.64270220674158 | 50.89221520368903 | 13.344350628715336 | 5.245693924323836 | 5.383583401845403 | 1.1498471629196398 | 1.2060491701414169 | 0.5439730365017541 | 0.8003064797316238 | 0.7382115374334658 | 0.6228413992840706 | 0.8710772912537195 | 0.9035240820265737 | 9.701712669072467 |
KO21 | 0.6658733788270118 | 0.6128597487487746 | 0.8929832431386732 | 7.348305311853368 | 39.29511568356362 | 6.886983563151546 | 4.615548646487691 | 3.4821517235473114 | 1.2297501069803567 | 0.9834446745537488 | 0.6596952194763461 | 0.6971828713130097 | 0.7028087797750208 | 0.30504965281593216 | 0.8016669791620175 | 0.7015233920954663 | 8.51363915608736 |
A
B
C
D
E
F
G
H
I
J
K
L
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
* The data in this sheet are relative means of each clone (WT, KO4, KO9, KO21) to the mean of the WT values in each biological replicate (N1, N2, N3). | |||||||||||
MCAD-KO (average for of biological replicate) vs WT | |||||||||||
KO4 | KO9 | KO21 | |||||||||
N=1 | N=2 | N=3 | N=1 | N=2 | N=3 | N=1 | N=2 | N=3 | |||
C0 | 0.5584234524812077 | 0.42309720137289497 | 1.1952060618988052 | 1.2251772835818198 | 0.3315936638131597 | 0.6320273628634081 | 0.32716449591837327 | 0.27793725189688173 | 0.6658733788270118 | ||
C2:0 | 0.38511911269583227 | 0.20368115893482955 | 0.4687072504498886 | 0.4857682328273938 | 0.37800787604462 | 0.6381888554060876 | 0.5640282967471729 | 0.36524192443686454 | 0.6128597487487746 | ||
C4:0 | 0.31278251215921093 | 0.42340786874343495 | 0.8174011473049042 | 0.8620342858141294 | 0.4827434028310449 | 0.6855364066079984 | 0.368481385076861 | 0.5999166955127444 | 0.8929832431386732 | ||
C6:0 | 2.5518197642736706 | 2.7873071655304074 | 6.466703860606872 | 4.377220797427618 | 5.119659474351154 | 6.64270220674158 | 2.4104709195593332 | 4.843351186490762 | 7.348305311853368 | ||
C8:0 | 17.81561193506573 | 41.9361603759529 | 47.08351903386612 | 27.350312790223644 | 74.53227151921149 | 50.89221520368903 | 11.977857832854502 | 47.0026595941664 | 39.29511568356362 | ||
C10:0 | 1.2872149453136692 | 2.270141033219879 | 4.40303832369796 | 1.4973139998610854 | 3.8133080069115723 | 5.24569392432384 | 0.8826036948547444 | 3.157276142016137 | 4.61554864648769 | ||
C12:0 | 0.21950212753651352 | 0.6616436464156386 | 1.1528018453861362 | 0.31046171256924904 | 1.1882538427778833 | 1.1498471629196398 | 0.2773114263087481 | 1.2295555644537088 | 1.2297501069803567 | ||
C14:0 | 0.3533027181381941 | 0.43301329494033913 | 0.5061053430883333 | 0.4685749274582786 | 0.526439745313904 | 0.5439730365017541 | 0.4373710874197449 | 0.6996121173682824 | 0.6596952194763461 | ||
C16:0 | 0.5727019406301113 | 0.4511271822842021 | 0.5934532350749306 | 0.8601809800196405 | 0.7288529904786547 | 0.7382115374334658 | 0.7955883576128574 | 0.7728310909951678 | 0.7028087797750208 | ||
MCAD KO (average of each clone) vs WT | |||||||||||
KO4 | KO9 | KO21 | |||||||||
C0 | 0.725575571917636 | 0.7295994367527959 | 0.4236583755474223 | ||||||||
C2:0 | 0.3525025073601835 | 0.5006549880927005 | 0.5140433233109373 | ||||||||
C4:0 | 0.5178638427358501 | 0.6767713650843908 | 0.6204604412427596 | ||||||||
C6:0 | 3.935276930136983 | 5.379860826173451 | 4.8673758059678205 | ||||||||
C8:0 | 35.61176378162825 | 50.92493317104138 | 32.75854437019484 | ||||||||
C10:0 | 2.6534647674105027 | 3.518771977032166 | 2.88514282778619 | ||||||||
C12:0 | 0.6779825397794293 | 0.8828542394222575 | 0.9122056992476045 | ||||||||
C14:0 | 0.43080711872228883 | 0.5129959030913123 | 0.5988928080881245 | ||||||||
C16:0 | 0.539094119329748 | 0.7757485026439204 | 0.757076076127682 | ||||||||
C8:0/C10:0 | 13.420854205040571 | 14.47235953436032 | 11.35421929711914 | ||||||||