Selected Cell
Cell:
Value:
Note on data sheet
N1
N2
N3
Combined_mean_clone_vs__mean_WT
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The sheets: "N1", "N2", and "N3" contain the normalised data (peak area/mg protein) and all of the data processing steps to get to relative level. | |||||||||
The data used for plotting, were: | |||||||||
Fig. 2: The mean of all of the data points pertaining to a single clone (e.g. all of the data points from KO4 in experiment N1) to the mean of the WT data in the same experiment. | |||||||||
Fig. S2 & S7: Each data point relative to the mean of all of the WT data pionts in one biological replicate (i.e. the ratio of each data point to the mean of all WT data within N0, N1, N2, and N3) | |||||||||
The final data plotted in the figures are summarised in "Combined_mean_clone_vs__mean_WT" | |||||||||
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area ratio / mg protein | ||||||||||||||||||||||||
Acylcarnitine chain-length: | C0 | C2:0 | C3:0 | C4:0 | C5:1 | C5:0 | C6:0 | C8:1 | C8:0 | C10:0 | C12:1 | C12:0 | C14:2 | C14:1 | C14:0 | C16:1 | C16:0 | C18:1-OH | C18:2 | C18:1 | C18:0 | C7-DC | C8/C10 | |
Group | Carnitine | Acetylcarnitine | Propionyl carnitine | Malonyl carnitine | Butyrylcarnitine | Tiglylcarnitine | 2-Methylbutyroylcarnitine | Hexanoylcarnitine | Octenoylcarnitine | Octanoylcarnitine | Decanoylcarnitine | Dodecenoylcarnitine | Lauroylcarnitine | Tetradecadienylcarnitine | Tetradecenoylcarnitine | Myristoylcarnitine | Hexadecenoylcarnitine | Palmitoylcarnitine | Hydroxyoctadecenoylcarnitine | Linoleylcarnitine | Oleoylcarnitine | Stearoylcarnitine | Pimelylcarnitine | |
WT_1 | 1.9205374009885472 | 1.0355792824287449 | 0.40959984143723044 | 0.028159128935321562 | 0.18215010269000534 | 0.007101450533654444 | 0.3386530064798144 | 0.025866046052444483 | 1.4599055163524074E-4 | 0.006876715381647448 | 0.0056976720306740735 | 0.008135871431309711 | 0.038774530150995634 | 2.5796399586302306E-4 | 0.0034029383676751025 | 0.08999640649431029 | 0.012536440153966707 | 0.2074312365921691 | 4.4326590900437856E-5 | 1.4739765676003003E-4 | 0.0066532492771992175 | 0.008037062922361029 | 5.807990245101399E-5 | 1.2069342258778426 |
WT_2 | 1.8224687767770726 | 1.0103392326499907 | 0.3882360314881645 | 0.020059499399019316 | 0.18637633631506637 | 0.008366821970812682 | 0.3485294984716541 | 0.01779266497795723 | 1.28207437726665E-4 | 0.005496605161460136 | 0.004179908844315445 | 0.005277507729651045 | 0.0233382822832875 | 2.1395300190061044E-4 | 0.003130352270296118 | 0.10277964302141863 | 0.015409735367931181 | 0.21928433663689953 | 5.946022721258272E-5 | 2.0706379973099544E-4 | 0.007320422232054681 | 0.008451790610873727 | 2.673089768738377E-5 | 1.3150059884524419 |
WT_3 | 2.0840397039526897 | 1.3095046142402482 | 0.46172045566794523 | 0.02289935955280069 | 0.24591504173908318 | 0.009794383046697226 | 0.42545388851410576 | 0.02458835691892839 | 1.923644054178602E-4 | 0.008938009536964378 | 0.008148643432513357 | 0.008901075517361277 | 0.059446356599001826 | 2.244091539463737E-4 | 0.004450838280135255 | 0.09923002399132735 | 0.01308754323507489 | 0.2315000337921974 | 5.9022162519356566E-5 | 2.2601264264200948E-4 | 0.007035093010600875 | 0.008998240674575218 | 6.857937975616276E-5 | 1.096870860897094 |
WT_4 | 2.588078007465005 | 1.240214897272455 | 0.5452425768603129 | 0.027345855876392655 | 0.30275188950916115 | 0.01229710921337095 | 0.5209221442758152 | 0.02423432756704057 | 2.0125080186725024E-4 | 0.0084121904428082 | 0.00665199326738583 | 0.008274379978882938 | 0.040520588073877255 | 4.008848918517583E-4 | 0.005046560326032275 | 0.09469267768389479 | 0.01735734618490403 | 0.227313626411764 | 6.314836278333554E-5 | 2.1372676352895403E-4 | 0.008457881435457015 | 0.008971084496743081 | 9.081671667131042E-5 | 1.2646119899207462 |
WT_5 | 4.220969152028936 | 1.8172297812334055 | 0.24002580271999188 | 0.05244251735714973 | 0.16590334504856935 | 0.004359038727806504 | 0.2882362157805063 | 0.043346513063851885 | 3.38026270409909E-4 | 0.013868179735622611 | 0.009015876905662702 | 0.014492365586988108 | 0.03899909703150928 | 3.6470050710009095E-4 | 0.0048758071326903876 | 0.1010953059977099 | 0.019079075854098917 | 0.32825085341632254 | 7.338267399266225E-4 | 1.6043008560886123E-4 | 0.006639607558734873 | 0.011131421354747206 | 1.5744328633360809E-4 | 1.5381953281673877 |
KO4_1 | 0.9587566936758878 | 0.11752854755390045 | 0.09259086420497242 | 0.002946512516555009 | 0.032897449658286025 | 0.0033364775240424015 | 0.08798336011498037 | 0.024106212423244625 | 4.550364215468551E-4 | 0.07851055269822522 | 0.006548068548523878 | 0.0018885641708641448 | 0.004617559060795252 | 7.914430045811962E-5 | 6.901919736966262E-4 | 0.008931195835179814 | 0.006647801742918878 | 0.07697074403408223 | 1.7601470778318692E-5 | 7.52548811696827E-5 | 0.002831308910617565 | 0.0033487730998002754 | 4.4030826580481447E-5 | 11.989879476127927 |
KO4_2 | 1.0468572352043075 | 0.13191099994336963 | 0.1396299508468097 | 0.004625776693253603 | 0.03663195588451502 | 0.0034486635152309675 | 0.09753593965712914 | 0.03184940499639405 | 5.44657694180004E-4 | 0.08510950503869959 | 0.006290072090151174 | 0.0017621183857060567 | 0.00559459634557757 | 9.062285548000445E-5 | 6.459020328799271E-4 | 0.00941590952855765 | 0.004714506796759635 | 0.07625297452280201 | 1.107034192966178E-5 | 7.310235411803561E-5 | 0.002887933960262008 | 0.003254257397976251 | 4.151779982128259E-5 | 13.530767822512205 |
KO4_3 | 1.5681854240668733 | 0.11967351137412284 | 0.19426777798757874 | 0.003246676828578457 | 0.04986531807868939 | 0.005488564079245469 | 0.13974118277426856 | 0.042734566713708975 | 4.7232067511884893E-4 | 0.10763095684313509 | 0.009052173094039224 | 0.0024277217176872775 | 0.007632473666224449 | 1.0381233969878858E-4 | 9.964270276432653E-4 | 0.012183851824377754 | 0.005749814857236694 | 0.08903422543096244 | 1.4132381757939428E-5 | 7.572404945004815E-5 | 0.0036429558467299303 | 0.0035562071771616894 | 4.897000513030693E-5 | 11.890068354305898 |
KO4_4 | 1.2873068041441447 | 0.12065875408314998 | 0.1427332760948014 | 0.0032300186112664765 | 0.035467784522697283 | 0.003720301331120654 | 0.09625217641202943 | 0.022907032258574905 | 4.271674392633883E-4 | 0.06337341333628412 | 0.004338789888573916 | 0.0013479108432133877 | 0.003259347358440869 | 5.674621831108318E-4 | 0.007300044887266916 | 0.00457967504510113 | 0.06994435220105653 | 3.2223902733052195E-6 | 5.409443753476168E-5 | 0.002761003268679673 | 0.0031496573312966634 | 2.8626286561804718E-5 | 14.60624159357803 | |
KO4_5 | 1.3579817897746451 | 0.12545774651415686 | 0.19227169688031331 | 0.0038012073831616695 | 0.04138868970063347 | 0.004305850906736492 | 0.1168784907685113 | 0.039934121304336816 | 4.8569645427056044E-4 | 0.0913087114871008 | 0.007379810735145807 | 0.0015693681839026251 | 0.005192823702962903 | 1.0808560335925846E-4 | 7.897390841160766E-4 | 0.008452005001285645 | 0.0067931585906408866 | 0.08630218956799032 | 5.771293881677581E-6 | 3.402103604843286E-5 | 0.0032116310932290846 | 0.0034746565008392945 | 4.69076524918375E-5 | 12.372771438737551 |
KO9_1 | 1.121281288689922 | 0.23256824802382572 | 0.1525302539904062 | 0.009714439488596677 | 0.055292278356993164 | 0.005709716542376026 | 0.08306035141133128 | 0.038002505143823785 | 6.549044869681075E-4 | 0.13455661477508796 | 0.005707833309026677 | 0.0036694669850928017 | 0.004591547799383257 | 4.118172484585961E-4 | 0.0018918446795503324 | 0.007608473567912737 | 0.012902255083472085 | 0.07662086221689382 | 3.096594608967828E-5 | 1.5254016644594237E-4 | 0.00633779380169303 | 0.0031987279753811467 | 6.23145298729075E-5 | 23.57402669105505 |
KO9_2 | 0.9530969674012824 | 0.2594384665267969 | 0.11956866645006785 | 0.0050499338279990594 | 0.048665215685847064 | 0.00447346147655004 | 0.07549299474305568 | 0.0383490684254064 | 5.031594781815922E-4 | 0.13735895526722314 | 0.005083404855797804 | 0.0029189628487166983 | 0.004952274247992942 | 2.1058047857398394E-4 | 0.0011244188699277569 | 0.008508333896486432 | 0.010858503333050785 | 0.07920959568858432 | 2.0752854930241412E-5 | 1.1496828301095961E-4 | 0.005485734635418471 | 0.003118420740958157 | 8.821750308781373E-5 | 27.021053637024476 |
KO9_3 | 1.4468974370395018 | 0.2589623024682301 | 0.13557739507438718 | 0.007970103675843944 | 0.06114451128812076 | 0.005618544644354291 | 0.07499541232561799 | 0.04530155150420173 | 6.052427947712698E-4 | 0.14791477880297507 | 0.0052316679460784775 | 0.0028648167605282147 | 0.0037930632578840485 | 2.629119516296121E-4 | 9.168940392245813E-4 | 0.007387753327747093 | 0.009605822975484981 | 0.06184119264488235 | 2.0632119344994013E-5 | 1.2098034620442767E-4 | 0.004649125421067093 | 0.0025543025984806297 | 8.423078687691071E-5 | 28.272967689749528 |
KO9_4 | 1.3627034117064467 | 0.308900343570622 | 0.1897478890185299 | 0.010484892275305531 | 0.07863961184485085 | 0.005439448397905738 | 0.10273280794940653 | 0.04402295843035154 | 5.274521828347525E-4 | 0.1445713130651897 | 0.005583133249022886 | 0.002728924272798395 | 0.0042947047536255325 | 2.632797039898E-4 | 0.0015879216772983298 | 0.008762978539006734 | 0.015230940880046734 | 0.08177206981772096 | 2.474586592203591E-5 | 1.6249193152932887E-4 | 0.006177757869568968 | 0.0032026724229384227 | 9.791892645192645E-5 | 25.894297452150433 |
KO9_5 | 1.1419331766318759 | 0.29091113362014115 | 0.1543171150707922 | 0.008596956466984575 | 0.06629159204413866 | 0.004626965667127518 | 0.09405474853352376 | 0.03995383207627483 | 5.096348511402164E-4 | 0.11544902678508902 | 0.005858813397161773 | 0.0025794962705792874 | 0.004414192262949292 | 3.1935471820250283E-4 | 0.0011481782208896737 | 0.007512272104318086 | 0.011125327086628015 | 0.07493035322647305 | 1.5046851457157908E-5 | 1.126731553495078E-4 | 0.005728459203293759 | 0.0030472672443010605 | 9.013950227538014E-5 | 19.705189252318025 |
KO21_1 | 1.8952726706584755 | 0.5050538751245813 | 0.6467551403114431 | 0.008924620065522195 | 0.1146513437734882 | 0.015826977135522034 | 0.3635498262793187 | 0.09561342092145325 | 9.132648105134188E-4 | 0.2103368222867386 | 0.009278444377134147 | 0.0046819180272362195 | 0.011466753410328252 | 1.664742655963557E-4 | 0.0010799755663435853 | 0.02018094749885008 | 0.012268651344957155 | 0.12227011727166584 | 3.492330135911354E-5 | 1.2908878877401992E-4 | 0.006905761967302479 | 0.004639468296607602 | 9.108210183157073E-5 | 22.669405962608767 |
KO21_2 | 1.5996470378976786 | 0.4203552520159567 | 0.6055751908938628 | 0.007555392274361336 | 0.07997343513400867 | 0.013463829484032633 | 0.299679902025161 | 0.0698888646254231 | 7.008643031567618E-4 | 0.14166684116980072 | 0.007021257543983863 | 0.002623316920869621 | 0.004165528808306751 | 1.1429901106457654E-4 | 9.330027378395272E-4 | 0.014755819653187653 | 0.009414195584868591 | 0.101173728084661 | 3.552821962560935E-5 | 9.378026671986715E-5 | 0.005626705608058339 | 0.0043067813827204334 | 5.8041297056424186E-5 | 20.176847278759542 |
KO21_3 | 1.729136370731861 | 0.3871943861447971 | 0.6378769497142099 | 0.007604393890274127 | 0.09223440169990356 | 0.011923439501046866 | 0.3337038341108409 | 0.07958195494466512 | 7.88188951843701E-4 | 0.14758732771621103 | 0.007167893422818647 | 0.0035215003521105164 | 0.0053335362277014235 | 1.5767558181961424E-4 | 0.0010703639074264306 | 0.013760949306676725 | 0.012590439284323808 | 0.10235908432827368 | 3.454573839598687E-5 | 1.2221209746188043E-4 | 0.006117433533799217 | 0.00426901542959911 | 8.338864523361814E-5 | 20.59005610300703 |
KO21_4 | 2.0394335254391973 | 0.41849951534608876 | 0.6304772568059112 | 0.006927839102452434 | 0.09193761694550132 | 0.011435480710907138 | 0.2798434710450602 | 0.08861114623056085 | 7.132057542785033E-4 | 0.1811008710323773 | 0.008517221307937204 | 0.002921198109705158 | 0.0092859264948199 | 1.01163565110601E-4 | 8.008473685028159E-4 | 0.01310038584537773 | 0.007921340318303684 | 0.09536319558317995 | 1.6090678694905066E-5 | 9.54999764843296E-5 | 0.004574686318128356 | 0.0038185813203572365 | 9.751047445311119E-5 | 21.26290541066595 |
KO21_5 | 2.114191043466986 | 0.4012359940489965 | 0.9231970919332818 | 0.008075836115724502 | 0.10938211130217285 | 0.014690709432482095 | 0.31988774477553605 | 0.0953058075230347 | 7.860847862566804E-4 | 0.18620401837131306 | 0.008083902747268591 | 0.0032239474695787726 | 0.0068050725464529884 | 1.4101153758741682E-4 | 0.0011347517065804329 | 0.01561471185005663 | 0.011516471755223126 | 0.09201974018758144 | 2.902952666380773E-5 | 1.1845491959379758E-4 | 0.006021251942645017 | 0.0043218257918328515 | 1.0092834526168969E-4 | 23.0339260865339 |
area ratio / mg protein - outliers removed | ||||||||||||||||||||||||
Acylcarnitine chain-length: | C0 | C2:0 | C3:0 | C4:0 | C5:1 | C5:0 | C6:0 | C8:1 | C8:0 | C10:0 | C12:1 | C12:0 | C14:2 | C14:1 | C14:0 | C16:1 | C16:0 | C18:1-OH | C18:2 | C18:1 | C18:0 | C7-DC | C8/C10 | |
Group | Carnitine | Acetylcarnitine | Propionyl carnitine | Malonyl carnitine | Butyrylcarnitine | Tiglylcarnitine | 2-Methylbutyroylcarnitine | Hexanoylcarnitine | Octenoylcarnitine | Octanoylcarnitine | Decanoylcarnitine | Dodecenoylcarnitine | Lauroylcarnitine | Tetradecadienylcarnitine | Tetradecenoylcarnitine | Myristoylcarnitine | Hexadecenoylcarnitine | Palmitoylcarnitine | Hydroxyoctadecenoylcarnitine | Linoleylcarnitine | Oleoylcarnitine | Stearoylcarnitine | Pimelylcarnitine | |
WT_1 | 1.9205374009885472 | 1.0355792824287449 | 0.40959984143723044 | 0.028159128935321562 | 0.18215010269000534 | 0.007101450533654444 | 0.3386530064798144 | 0.025866046052444483 | 1.4599055163524074E-4 | 0.006876715381647448 | 0.0056976720306740735 | 0.008135871431309711 | 0.038774530150995634 | 2.5796399586302306E-4 | 0.0034029383676751025 | 0.08999640649431029 | 0.012536440153966707 | 0.2074312365921691 | 4.4326590900437856E-5 | 1.4739765676003003E-4 | 0.0066532492771992175 | 0.008037062922361029 | 5.807990245101399E-5 | 1.2069342258778426 |
WT_2 | 1.8224687767770726 | 1.0103392326499907 | 0.3882360314881645 | 0.020059499399019316 | 0.18637633631506637 | 0.008366821970812682 | 0.3485294984716541 | 0.01779266497795723 | 1.28207437726665E-4 | 0.005496605161460136 | 0.004179908844315445 | 0.005277507729651045 | 0.0233382822832875 | 2.1395300190061044E-4 | 0.003130352270296118 | 0.10277964302141863 | 0.015409735367931181 | 0.21928433663689953 | 5.946022721258272E-5 | 2.0706379973099544E-4 | 0.007320422232054681 | 0.008451790610873727 | 2.673089768738377E-5 | 1.3150059884524419 |
WT_3 | 2.0840397039526897 | 1.3095046142402482 | 0.46172045566794523 | 0.02289935955280069 | 0.24591504173908318 | 0.009794383046697226 | 0.42545388851410576 | 0.02458835691892839 | 1.923644054178602E-4 | 0.008938009536964378 | 0.008148643432513357 | 0.008901075517361277 | 0.059446356599001826 | 2.244091539463737E-4 | 0.004450838280135255 | 0.09923002399132735 | 0.01308754323507489 | 0.2315000337921974 | 5.9022162519356566E-5 | 2.2601264264200948E-4 | 0.007035093010600875 | 0.008998240674575218 | 6.857937975616276E-5 | 1.096870860897094 |
WT_4 | 2.588078007465005 | 1.240214897272455 | 0.5452425768603129 | 0.027345855876392655 | 0.30275188950916115 | 0.01229710921337095 | 0.5209221442758152 | 0.02423432756704057 | 2.0125080186725024E-4 | 0.0084121904428082 | 0.00665199326738583 | 0.008274379978882938 | 0.040520588073877255 | 4.008848918517583E-4 | 0.005046560326032275 | 0.09469267768389479 | 0.01735734618490403 | 0.227313626411764 | 6.314836278333554E-5 | 2.1372676352895403E-4 | 0.008457881435457015 | 0.008971084496743081 | 9.081671667131042E-5 | 1.2646119899207462 |
WT_5 | 4.220969152028936 | 1.8172297812334055 | 0.24002580271999188 | 0.05244251735714973 | 0.16590334504856935 | 0.004359038727806504 | 0.2882362157805063 | 0.043346513063851885 | 3.38026270409909E-4 | 0.013868179735622611 | 0.009015876905662702 | 0.014492365586988108 | 0.03899909703150928 | 3.6470050710009095E-4 | 0.0048758071326903876 | 0.1010953059977099 | 0.019079075854098917 | 0.32825085341632254 | 1.6043008560886123E-4 | 0.006639607558734873 | 0.011131421354747206 | 1.5744328633360809E-4 | 1.5381953281673877 | |
KO4_1 | 0.9587566936758878 | 0.11752854755390045 | 0.09259086420497242 | 0.002946512516555009 | 0.032897449658286025 | 0.0033364775240424015 | 0.08798336011498037 | 0.024106212423244625 | 4.550364215468551E-4 | 0.07851055269822522 | 0.006548068548523878 | 0.0018885641708641448 | 0.004617559060795252 | 7.914430045811962E-5 | 6.901919736966262E-4 | 0.008931195835179814 | 0.006647801742918878 | 0.07697074403408223 | 1.7601470778318692E-5 | 7.52548811696827E-5 | 0.002831308910617565 | 0.0033487730998002754 | 4.4030826580481447E-5 | 11.989879476127927 |
KO4_2 | 1.0468572352043075 | 0.13191099994336963 | 0.1396299508468097 | 0.004625776693253603 | 0.03663195588451502 | 0.0034486635152309675 | 0.09753593965712914 | 0.03184940499639405 | 5.44657694180004E-4 | 0.08510950503869959 | 0.006290072090151174 | 0.0017621183857060567 | 0.00559459634557757 | 9.062285548000445E-5 | 6.459020328799271E-4 | 0.00941590952855765 | 0.004714506796759635 | 0.07625297452280201 | 1.107034192966178E-5 | 7.310235411803561E-5 | 0.002887933960262008 | 0.003254257397976251 | 4.151779982128259E-5 | 13.530767822512205 |
KO4_3 | 1.5681854240668733 | 0.11967351137412284 | 0.19426777798757874 | 0.003246676828578457 | 0.04986531807868939 | 0.005488564079245469 | 0.13974118277426856 | 0.042734566713708975 | 4.7232067511884893E-4 | 0.10763095684313509 | 0.009052173094039224 | 0.0024277217176872775 | 0.007632473666224449 | 1.0381233969878858E-4 | 9.964270276432653E-4 | 0.012183851824377754 | 0.005749814857236694 | 0.08903422543096244 | 1.4132381757939428E-5 | 7.572404945004815E-5 | 0.0036429558467299303 | 0.0035562071771616894 | 4.897000513030693E-5 | 11.890068354305898 |
KO4_4 | 1.2873068041441447 | 0.12065875408314998 | 0.1427332760948014 | 0.0032300186112664765 | 0.035467784522697283 | 0.003720301331120654 | 0.09625217641202943 | 0.022907032258574905 | 4.271674392633883E-4 | 0.06337341333628412 | 0.004338789888573916 | 0.0013479108432133877 | 0.003259347358440869 | 5.674621831108318E-4 | 0.007300044887266916 | 0.00457967504510113 | 0.06994435220105653 | 3.2223902733052195E-6 | 5.409443753476168E-5 | 0.002761003268679673 | 0.0031496573312966634 | 2.8626286561804718E-5 | 14.60624159357803 | |
KO4_5 | 1.3579817897746451 | 0.12545774651415686 | 0.19227169688031331 | 0.0038012073831616695 | 0.04138868970063347 | 0.004305850906736492 | 0.1168784907685113 | 0.039934121304336816 | 4.8569645427056044E-4 | 0.0913087114871008 | 0.007379810735145807 | 0.0015693681839026251 | 0.005192823702962903 | 1.0808560335925846E-4 | 7.897390841160766E-4 | 0.008452005001285645 | 0.0067931585906408866 | 0.08630218956799032 | 5.771293881677581E-6 | 3.402103604843286E-5 | 0.0032116310932290846 | 0.0034746565008392945 | 4.69076524918375E-5 | 12.372771438737551 |
KO9_1 | 1.121281288689922 | 0.23256824802382572 | 0.1525302539904062 | 0.009714439488596677 | 0.055292278356993164 | 0.005709716542376026 | 0.08306035141133128 | 0.038002505143823785 | 6.549044869681075E-4 | 0.13455661477508796 | 0.005707833309026677 | 0.0036694669850928017 | 0.004591547799383257 | 4.118172484585961E-4 | 0.0018918446795503324 | 0.007608473567912737 | 0.012902255083472085 | 0.07662086221689382 | 3.096594608967828E-5 | 1.5254016644594237E-4 | 0.00633779380169303 | 0.0031987279753811467 | 6.23145298729075E-5 | 23.57402669105505 |
KO9_2 | 0.9530969674012824 | 0.2594384665267969 | 0.11956866645006785 | 0.0050499338279990594 | 0.048665215685847064 | 0.00447346147655004 | 0.07549299474305568 | 0.0383490684254064 | 5.031594781815922E-4 | 0.13735895526722314 | 0.005083404855797804 | 0.0029189628487166983 | 0.004952274247992942 | 2.1058047857398394E-4 | 0.0011244188699277569 | 0.008508333896486432 | 0.010858503333050785 | 0.07920959568858432 | 2.0752854930241412E-5 | 1.1496828301095961E-4 | 0.005485734635418471 | 0.003118420740958157 | 8.821750308781373E-5 | 27.021053637024476 |
KO9_3 | 1.4468974370395018 | 0.2589623024682301 | 0.13557739507438718 | 0.007970103675843944 | 0.06114451128812076 | 0.005618544644354291 | 0.07499541232561799 | 0.04530155150420173 | 6.052427947712698E-4 | 0.14791477880297507 | 0.0052316679460784775 | 0.0028648167605282147 | 0.0037930632578840485 | 2.629119516296121E-4 | 9.168940392245813E-4 | 0.007387753327747093 | 0.009605822975484981 | 0.06184119264488235 | 2.0632119344994013E-5 | 1.2098034620442767E-4 | 0.004649125421067093 | 0.0025543025984806297 | 8.423078687691071E-5 | 28.272967689749528 |
KO9_4 | 1.3627034117064467 | 0.308900343570622 | 0.1897478890185299 | 0.010484892275305531 | 0.07863961184485085 | 0.005439448397905738 | 0.10273280794940653 | 0.04402295843035154 | 5.274521828347525E-4 | 0.1445713130651897 | 0.005583133249022886 | 0.002728924272798395 | 0.0042947047536255325 | 2.632797039898E-4 | 0.0015879216772983298 | 0.008762978539006734 | 0.015230940880046734 | 0.08177206981772096 | 2.474586592203591E-5 | 1.6249193152932887E-4 | 0.006177757869568968 | 0.0032026724229384227 | 9.791892645192645E-5 | 25.894297452150433 |
KO9_5 | 1.1419331766318759 | 0.29091113362014115 | 0.1543171150707922 | 0.008596956466984575 | 0.06629159204413866 | 0.004626965667127518 | 0.09405474853352376 | 0.03995383207627483 | 5.096348511402164E-4 | 0.11544902678508902 | 0.005858813397161773 | 0.0025794962705792874 | 0.004414192262949292 | 3.1935471820250283E-4 | 0.0011481782208896737 | 0.007512272104318086 | 0.011125327086628015 | 0.07493035322647305 | 1.5046851457157908E-5 | 1.126731553495078E-4 | 0.005728459203293759 | 0.0030472672443010605 | 9.013950227538014E-5 | 19.705189252318025 |
KO21_1 | 1.8952726706584755 | 0.5050538751245813 | 0.6467551403114431 | 0.008924620065522195 | 0.1146513437734882 | 0.015826977135522034 | 0.3635498262793187 | 0.09561342092145325 | 9.132648105134188E-4 | 0.2103368222867386 | 0.009278444377134147 | 0.0046819180272362195 | 0.011466753410328252 | 1.664742655963557E-4 | 0.0010799755663435853 | 0.02018094749885008 | 0.012268651344957155 | 0.12227011727166584 | 3.492330135911354E-5 | 1.2908878877401992E-4 | 0.006905761967302479 | 0.004639468296607602 | 9.108210183157073E-5 | 22.669405962608767 |
KO21_2 | 1.5996470378976786 | 0.4203552520159567 | 0.6055751908938628 | 0.007555392274361336 | 0.07997343513400867 | 0.013463829484032633 | 0.299679902025161 | 0.0698888646254231 | 7.008643031567618E-4 | 0.14166684116980072 | 0.007021257543983863 | 0.002623316920869621 | 0.004165528808306751 | 1.1429901106457654E-4 | 9.330027378395272E-4 | 0.014755819653187653 | 0.009414195584868591 | 0.101173728084661 | 3.552821962560935E-5 | 9.378026671986715E-5 | 0.005626705608058339 | 0.0043067813827204334 | 5.8041297056424186E-5 | 20.176847278759542 |
KO21_3 | 1.729136370731861 | 0.3871943861447971 | 0.6378769497142099 | 0.007604393890274127 | 0.09223440169990356 | 0.011923439501046866 | 0.3337038341108409 | 0.07958195494466512 | 7.88188951843701E-4 | 0.14758732771621103 | 0.007167893422818647 | 0.0035215003521105164 | 0.0053335362277014235 | 1.5767558181961424E-4 | 0.0010703639074264306 | 0.013760949306676725 | 0.012590439284323808 | 0.10235908432827368 | 3.454573839598687E-5 | 1.2221209746188043E-4 | 0.006117433533799217 | 0.00426901542959911 | 8.338864523361814E-5 | 20.59005610300703 |
KO21_4 | 2.0394335254391973 | 0.41849951534608876 | 0.6304772568059112 | 0.006927839102452434 | 0.09193761694550132 | 0.011435480710907138 | 0.2798434710450602 | 0.08861114623056085 | 7.132057542785033E-4 | 0.1811008710323773 | 0.008517221307937204 | 0.002921198109705158 | 0.0092859264948199 | 1.01163565110601E-4 | 8.008473685028159E-4 | 0.01310038584537773 | 0.007921340318303684 | 0.09536319558317995 | 1.6090678694905066E-5 | 9.54999764843296E-5 | 0.004574686318128356 | 0.0038185813203572365 | 9.751047445311119E-5 | 21.26290541066595 |
KO21_5 | 2.114191043466986 | 0.4012359940489965 | 0.9231970919332818 | 0.008075836115724502 | 0.10938211130217285 | 0.014690709432482095 | 0.31988774477553605 | 0.0953058075230347 | 7.860847862566804E-4 | 0.18620401837131306 | 0.008083902747268591 | 0.0032239474695787726 | 0.0068050725464529884 | 1.4101153758741682E-4 | 0.0011347517065804329 | 0.01561471185005663 | 0.011516471755223126 | 0.09201974018758144 | 2.902952666380773E-5 | 1.1845491959379758E-4 | 0.006021251942645017 | 0.0043218257918328515 | 1.0092834526168969E-4 | 23.0339260865339 |
Mean per clone | ||||||||||||||||||||||||
Acylcarnitine chain-length: | C0 | C2:0 | C3:0 | Malonyl carnitine | C4:0 | C5:1 | C5:0 | C6:0 | C8:1 | C8:0 | C10:0 | C12:1 | C12:0 | C14:2 | C14:1 | C14:0 | C16:1 | C16:0 | C18:1-OH | C18:2 | C18:1 | C18:0 | C7-DC | C8/C10 |
WT | 2.5272186082424497 | 1.282573561564969 | 0.40896494163472896 | 0.03018127222413679 | 0.2166193430603771 | 0.008383760698468362 | 0.38435895070437914 | 0.027165581716044513 | 2.0116789341138503E-4 | 0.008718340051700555 | 0.006738818896110282 | 0.009016240048838617 | 0.040215770827734296 | 2.9238231013237133E-4 | 0.0041812992753658285 | 0.09755881143773218 | 0.015494028159195145 | 0.24275601736987049 | 5.648933585392817E-5 | 1.9092618965417004E-4 | 0.007221250702809333 | 0.009117920011860053 | 8.033003657989581E-5 | 1.2843236786631025 |
KO4 | 1.2438175893731718 | 0.12304591189373996 | 0.15229871320289512 | 0.0035700384065630426 | 0.039250239568964236 | 0.004059971471275197 | 0.10767822994538376 | 0.03230626753925188 | 4.7697573687593135E-4 | 0.08518662788068895 | 0.0067217828712868 | 0.0017991366602746982 | 0.005259360026800208 | 9.541627474904277E-5 | 7.379444602893454E-4 | 0.009256601415333557 | 0.005696991406531445 | 0.07970089715137871 | 1.035957572418054E-5 | 6.24393516641922E-5 | 0.003066966615903652 | 0.0033567103014148342 | 4.2010514117142636E-5 | 12.877945737052324 |
KO9 | 1.2051824562938058 | 0.27015609884192315 | 0.15034826392083667 | 0.008363265146945959 | 0.062006641843990094 | 0.005173627345662723 | 0.08606726299258705 | 0.041125983116011657 | 5.600787587791877E-4 | 0.13597013773911298 | 0.005492970551417524 | 0.0029523334275430796 | 0.0044091564643670145 | 2.93588820170899E-4 | 0.0013338514973781348 | 0.007955962287094217 | 0.01194456987173652 | 0.07487481471891091 | 2.24287275488215E-5 | 1.3273077650803326E-4 | 0.005675774186208264 | 0.003024278196411883 | 8.45642497129877E-5 | 24.893506944459503 |
KO21 | 1.8755361296388398 | 0.4264678045360841 | 0.6887763259317418 | 0.007817616289666918 | 0.09763578177101492 | 0.013468087252798152 | 0.31933295564718334 | 0.0858002388490274 | 7.803217212098131E-4 | 0.17337917611528814 | 0.00801374387982849 | 0.0033943761759000573 | 0.007411363497521863 | 1.3612479223571285E-4 | 0.0010037882573385583 | 0.015482562830829766 | 0.010742219657535272 | 0.10263717309107238 | 3.002349294788451E-5 | 1.1180720980677895E-4 | 0.005849167873986681 | 0.0042711344442234464 | 8.61901727672828E-5 | 21.546628168315035 |
Replicates vs. mean WT | ||||||||||||||||||||||||
Acylcarnitine chain-length: | C0 | C2:0 | C3:0 | Malonyl carnitine | C4:0 | C5:1 | C5:0 | C6:0 | C8:1 | C8:0 | C10:0 | C12:1 | C12:0 | C14:2 | C14:1 | C14:0 | C16:1 | C16:0 | C18:1-OH | C18:2 | C18:1 | C18:0 | C7-DC | C8/C10 |
WT_1 | 0.7599411442780496 | 0.8074229139458895 | 1.0015524553277444 | 0.9330000646162933 | 0.8408764430572373 | 0.8470483341624738 | 0.881085261210117 | 0.9521624209198326 | 0.7257149695189802 | 0.7887642992665916 | 0.8455000970515516 | 0.9023574557953006 | 0.9641623013291908 | 0.8822831851428838 | 0.8138471186990972 | 0.9224836298026379 | 0.8091143261881052 | 0.8544844277788614 | 0.7846895388371867 | 0.7720138186752459 | 0.9213430679827884 | 0.8814579325007119 | 0.7230160090024115 | 0.932896757809005 |
WT_2 | 0.7211361814261512 | 0.7877436920009456 | 0.9493137234118256 | 0.664633990577017 | 0.8603863980102586 | 0.997979578823287 | 0.9067812726435439 | 0.6549708805774823 | 0.6373156051521746 | 0.6304646445154426 | 0.6202732123767465 | 0.5853335427034068 | 0.5803266182129859 | 0.7317576833008355 | 0.7486553973160025 | 1.0535147108369467 | 0.9945596593475958 | 0.9033116419223142 | 1.052592074481753 | 1.0845227682281613 | 1.0137332898865798 | 0.9269428334400978 | 0.33276341982985863 | 1.0164305534002425 |
WT_3 | 0.8246376855392149 | 1.0209976670986565 | 1.1289976442047578 | 0.7587274447127993 | 1.1352404557451763 | 1.1682565138681227 | 1.1069181236300487 | 0.9051290407083767 | 0.9562381061697462 | 1.025196251116745 | 1.2092094413186918 | 0.9872269892046436 | 1.4781851839578666 | 0.7675196007746711 | 1.064462978375506 | 1.017130308671932 | 0.8446830676054959 | 0.9536325249539619 | 1.04483725338846 | 1.183769723008627 | 0.9742208517790367 | 0.9868742720785921 | 0.8537202605149332 | 0.8478235581742787 |
WT_4 | 1.0240815729292527 | 0.9669736960421756 | 1.3332257153409046 | 0.9060537830649639 | 1.3976216769560454 | 1.46677722034904 | 1.3553011925991818 | 0.8920967649563459 | 1.0004121356269098 | 0.9648844152583106 | 0.9871156014038945 | 0.9177195742418994 | 1.0075795450359177 | 1.3710983118994586 | 1.2069359291654012 | 0.9706214773263538 | 1.120260400107965 | 0.9363871959780178 | 1.1178811332926002 | 1.1194208815253859 | 1.1712488298137311 | 0.9838959417360564 | 1.1305449435589965 | 0.9774786396710108 |
WT_5 | 1.6702034158273322 | 1.4168620309123325 | 0.5869104617147679 | 1.7375847170289265 | 0.7658750262312818 | 0.5199383527970761 | 0.7499141499171085 | 1.5956408928379622 | 1.6803191835321893 | 1.59069038984291 | 1.3379016478491152 | 1.6073624380547489 | 0.9697463514640392 | 1.2473412188821504 | 1.166098576443992 | 1.0362498733621301 | 1.2313825467508381 | 1.3521842093668455 | 0.8402728085625799 | 0.9194539605378638 | 1.2208290202445415 | 1.9599553670938001 | 1.188944189133926 | |
KO4_1 | 0.3793722832480462 | 0.09163493703276919 | 0.22640293770626152 | 0.09762718067923598 | 0.15186755343966074 | 0.39796907903775763 | 0.2289093566150636 | 0.8873806817472653 | 2.2619733886476263 | 9.005217992490595 | 0.9716938011649924 | 0.20946249885032853 | 0.11481960847088404 | 0.27068771849530954 | 0.16506638923525516 | 0.09154678807131873 | 0.4290557416454448 | 0.3170703855995761 | 0.3115892674651567 | 0.39415693208979863 | 0.3920801294872759 | 0.36727379659444137 | 0.5481240698389155 | 9.267547021185042 |
KO4_2 | 0.41423295625871587 | 0.10284868166346314 | 0.3414227886837341 | 0.15326645805057357 | 0.16910750151386433 | 0.41135042366619645 | 0.25376263380463504 | 1.1724175587075016 | 2.7074782409049143 | 9.762122667158247 | 0.9334086858725155 | 0.19543827317830068 | 0.1391144874368373 | 0.3099464377272908 | 0.1544740020608585 | 0.0965152136418497 | 0.30427896143726485 | 0.31411363289347694 | 0.19597224435932128 | 0.38288280015668863 | 0.3999215757927495 | 0.35690786865242347 | 0.5168402952236828 | 10.458572771939636 |
KO4_3 | 0.6205183116934492 | 0.09330732751741723 | 0.47502305994994287 | 0.10757256369007535 | 0.23019790095472084 | 0.6546661190184234 | 0.36356947722481237 | 1.5731143606790177 | 2.3478929321636874 | 12.345349711627863 | 1.3432877828582446 | 0.26926098956293787 | 0.18978807341324935 | 0.35505684202231397 | 0.23830559881559454 | 0.12488725154420532 | 0.371098774196069 | 0.366764236765786 | 0.25017787064240526 | 0.3966142601348157 | 0.5044771323771776 | 0.39002394981925537 | 0.6096101435432765 | 9.190398266974078 |
KO4_4 | 0.5093769094393461 | 0.09407550389228726 | 0.349011031420598 | 0.10702062481923284 | 0.1637332290903105 | 0.4437508971123567 | 0.2504226224877474 | 0.8432373176476311 | 2.123437453261182 | 7.2689770025571345 | 0.6438501991911835 | 0.1494981096235356 | 0.08104649721628863 | 0 | 0.13571431886113525 | 0.07482711996677242 | 0.2955767859750054 | 0.2881261315738558 | 0.05704422303065792 | 0.283326439566748 | 0.38234419248254886 | 0.345435946707119 | 0.3563584405110182 | 11.289857503637583 |
KO4_5 | 0.5373424306649323 | 0.09781719370628224 | 0.47014224767472285 | 0.12594589634699824 | 0.19106645378892792 | 0.5135942045105286 | 0.30408681924622516 | 1.4700263635713333 | 2.414383558102481 | 10.473176194737965 | 1.0951193152564929 | 0.17406015982291595 | 0.12912406242830832 | 0.36967217103635464 | 0.18887408724097635 | 0.08663497306627414 | 0.4384372172842214 | 0.35550999107263187 | 0.10216607779920031 | 0.1781894674065204 | 0.44474720867669665 | 0.3810799498481744 | 0.5839366504605461 | 9.563502395430762 |
KO9_1 | 0.4436819533667945 | 0.18132936386124388 | 0.3729665760118873 | 0.32186978124890886 | 0.25525088191954237 | 0.6810447897706742 | 0.21610099428961976 | 1.3989210884955494 | 3.2555119798805996 | 15.433742429998704 | 0.8470079693522109 | 0.40698417136370124 | 0.11417281590974142 | 1.4084889344781242 | 0.45245378408959064 | 0.07798858407340188 | 0.8327243858670196 | 0.31562909561229097 | 0.5481733077859324 | 0.7989483617844291 | 0.8776587411966454 | 0.3508177272031812 | 0.7757313767799647 | 18.22148431708663 |
KO9_2 | 0.37713277525449695 | 0.20227959962798206 | 0.2923689888236478 | 0.16732011130930685 | 0.22465775677420866 | 0.5335864938710979 | 0.1964127402385365 | 1.4116785285977036 | 2.501191763999036 | 15.755172940338637 | 0.7543465604531974 | 0.3237450237466437 | 0.12314259172617098 | 0.7202230479629463 | 0.2689161420595467 | 0.08721235705005442 | 0.7008186135641336 | 0.32629302682906586 | 0.36737650773421676 | 0.6021608833193858 | 0.7596654459433625 | 0.3420101006481631 | 1.098188259880513 | 20.885855078166223 |
KO9_3 | 0.5725256344348242 | 0.20190834290412926 | 0.33151348996432917 | 0.26407447693573477 | 0.2822670885447118 | 0.6701699686371951 | 0.19511816282196842 | 1.6676083721573967 | 3.008645089967504 | 16.965933643999534 | 0.7763479070639889 | 0.31773962816099066 | 0.0943178056721024 | 0.8992060823056737 | 0.21928448045478896 | 0.07572615142469623 | 0.6199693763809427 | 0.2547462811216713 | 0.36523919131117366 | 0.633649822601932 | 0.6438116626055389 | 0.2801409307339989 | 1.048559050426116 | 21.85351887939224 |
KO9_4 | 0.5392107383437386 | 0.24084415337059373 | 0.46397103932689926 | 0.3473972931770741 | 0.36303134675711796 | 0.6488076882847428 | 0.26728350611098717 | 1.6205417167397058 | 2.621950122806732 | 16.58243567099569 | 0.8285032340378713 | 0.3026676594696376 | 0.1067915562783082 | 0.9004638614100983 | 0.37976752504983036 | 0.08982252253657054 | 0.9830200851292323 | 0.3368487862985927 | 0.4380626103663976 | 0.8510719866334475 | 0.8554969386626603 | 0.3512503310812746 | 1.2189578222653594 | 20.01493173439767 |
KO9_5 | 0.451853738694189 | 0.2268182834403491 | 0.3773358040274808 | 0.2848440716196633 | 0.30602803566651743 | 0.5518961995149532 | 0.2447054982358504 | 1.4707519424359439 | 2.533380662778138 | 13.242088069571238 | 0.8694125020251757 | 0.28609445363109565 | 0.10976271676745035 | 1.0922504786897682 | 0.27459843107958776 | 0.077002497197425 | 0.7180396842137876 | 0.3086652765122064 | 0.2663662305406902 | 0.5901398627060848 | 0.7932779845276909 | 0.3342064023743743 | 1.12211454286751 | 15.231076202292504 |
KO21_1 | 0.7499440944590622 | 0.3937816046265022 | 1.5814439685861845 | 0.29570059205075294 | 0.5292756507969469 | 1.8878135606152835 | 0.945860179951773 | 3.51965299034926 | 4.539813958511795 | 24.125787826515367 | 1.3768650738617956 | 0.5192761064341114 | 0.285130762740978 | 0.5693718799916014 | 0.2582870766286148 | 0.206859300574103 | 0.7918309699002422 | 0.5036749185309436 | 0.6182282165508064 | 0.6761188132850818 | 0.9563110673634255 | 0.5088296772260401 | 1.1338486288498197 | 17.52226001262998 |
KO21_2 | 0.6329674182836722 | 0.3277435810411125 | 1.4807508645441256 | 0.2503337903800848 | 0.3691887991356253 | 1.6059415300930948 | 0.7796875849410175 | 2.5726989893297736 | 3.4839769471737014 | 16.249290613775486 | 1.0419121885048146 | 0.2909546448031329 | 0.10357948443037296 | 0.3909231410505975 | 0.22313703860814824 | 0.15125050659935205 | 0.6076015538465126 | 0.4167712470357001 | 0.6289367557352646 | 0.49118597553187426 | 0.7791871297127717 | 0.47234252736571786 | 0.722535424202087 | 15.59564308110635 |
KO21_3 | 0.6842053018651941 | 0.3018886383969671 | 1.55973504028112 | 0.25195736726408385 | 0.4257902382900108 | 1.4222065645582145 | 0.8682088279700335 | 2.9295141100425064 | 3.9180653457053785 | 16.928374764118473 | 1.0636720667706372 | 0.39057304741615895 | 0.13262300132323257 | 0.5392788016081725 | 0.25598835121238306 | 0.14105285933562012 | 0.8125994838115638 | 0.42165415892581665 | 0.6115444246913484 | 0.6401012751746978 | 0.8471432145984503 | 0.468200579084509 | 1.0380755292035784 | 15.915031796890075 |
KO21_4 | 0.8069873808255623 | 0.32629669586783355 | 1.5416413306376469 | 0.22954098988948687 | 0.4244201632532698 | 1.3640037117228667 | 0.7280784551321542 | 3.261890253512422 | 3.545325957259041 | 20.77240276915474 | 1.2639041706334375 | 0.32399293872853774 | 0.23090261118197886 | 0.34599755732417886 | 0.19153074577106144 | 0.1342819336594642 | 0.5112511889687419 | 0.3928355581723096 | 0.28484453661329684 | 0.500193172331734 | 0.633503323233001 | 0.4187996072997187 | 1.2138731488828318 | 16.435108967750402 |
KO21_5 | 0.836568327160782 | 0.31283663259003786 | 2.2573991018473274 | 0.267577723554875 | 0.5049508033624004 | 1.7522815787389967 | 0.8322630296219389 | 3.5083293455389275 | 3.907605597127519 | 21.357737512772637 | 1.1996023148707418 | 0.35757116626392943 | 0.1692140273924566 | 0.4822847781850282 | 0.27138734442325985 | 0.16005434691076434 | 0.7432845504665303 | 0.37906265387183935 | 0.5138939274993983 | 0.6204225821945031 | 0.8338239718366969 | 0.47399250993771336 | 1.2564210046301536 | 17.80401492062305 |
Mean Clone vs. mean WT (for WT, this should be 1 everywhere) | ||||||||||||||||||||||||
Acylcarnitine chain-length: | C0 | C2:0 | C3:0 | Malonyl carnitine | C4:0 | C5:1 | C5:0 | C6:0 | C8:1 | C8:0 | C10:0 | C12:1 | C12:0 | C14:2 | C14:1 | C14:0 | C16:1 | C16:0 | C18:1-OH | C18:2 | C18:1 | C18:0 | C7-DC | C8/C10 |
WT | 1.0000000000000002 | 1 | 1.0000000000000002 | 1 | 0.9999999999999998 | 0.9999999999999998 | 1 | 1 | 1 | 1 | 1 | 0.9999999999999998 | 1 | 0.9999999999999998 | 0.9999999999999998 | 1.0000000000000002 | 1 | 1 | 0.9999999999999999 | 1 | 1 | 1 | 1 | 0.9927147396376927 |
KO4 | 0.49216857826089794 | 0.0959367287624438 | 0.37240041308705185 | 0.11828654471722319 | 0.18119452775749686 | 0.4842661446690526 | 0.28015018187569674 | 1.1892352564705497 | 2.371033114615978 | 9.770968713714362 | 0.9974719568686858 | 0.1995440062076037 | 0.13077854579311352 | 0.2610726338562538 | 0.17648687924276396 | 0.09488226925808407 | 0.3676894961076011 | 0.32831687558106537 | 0.18338993665934827 | 0.32703397987091426 | 0.42471404776328975 | 0.3681443023242828 | 0.5229739199154878 | 9.95397559183342 |
KO9 | 0.47688096801880864 | 0.2106359486408596 | 0.36763117963084885 | 0.2771011468581376 | 0.2862470219324197 | 0.6171010280157326 | 0.22392418033939246 | 1.51390032968526 | 2.7841359238864016 | 15.595874550980762 | 0.8151236345864887 | 0.32744618727441377 | 0.10963749727075467 | 1.004126480969322 | 0.31900407254666885 | 0.0815504224564296 | 0.7709144290310231 | 0.30843649327476547 | 0.3970435695476821 | 0.6951941834090558 | 0.7859821545871796 | 0.33168509840819843 | 1.0527102104438926 | 19.241373242267052 |
KO21 | 0.7421345045188545 | 0.3325094305044906 | 1.6841940611792807 | 0.2590220926278567 | 0.45072513096765066 | 1.6064493891456912 | 0.8308196155233833 | 3.1584171377545776 | 3.8789575611554867 | 19.886718697267337 | 1.1891911629282852 | 0.37647358072917403 | 0.1842899774138038 | 0.46557123163191577 | 0.2400661113286935 | 0.15869978941586077 | 0.6933135493987181 | 0.42279970730732186 | 0.5314895722180228 | 0.5856043637035782 | 0.8099937413488691 | 0.4684329801827397 | 1.072950747153694 | 16.65441175579997 |
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area ratio / mg protein | |||||||||||||||||||||||
Acylcarnitine chain-length: | C0 | C2:0 | C3:0 | C4:0 | C5:1 | C5:0 | C6:0 | C8:0 | C10:0 | C12:1 | C12:0 | C14:2 | C14:1 | C14:0 | C16:1 | C16:0 | C18:1-OH | C18:2 | C18:1 | C18:0 | C7-DC | C8/C10 | |
Group | Carnitine | Acetylcarnitine | Propionyl carnitine | Malonyl carnitine | Butyrylcarnitine | Tiglylcarnitine | 2-Methylbutyroylcarnitine | Hexanoylcarnitine | Octanoylcarnitine | Decanoylcarnitine | Dodecenoylcarnitine | Lauroylcarnitine | Tetradecadienylcarnitine | Tetradecenoylcarnitine | Myristoylcarnitine | Hexadecenoylcarnitine | Palmitoylcarnitine | Hydroxyoctadecenoylcarnitine | Linoleylcarnitine | Oleoylcarnitine | Stearoylcarnitine | Pimelylcarnitine | |
WT_1 | 0.8236685962373371 | 0.5306029908345392 | 0.6817631452001929 | 0.041337674867342016 | 0.13542715870718763 | 0.004102918475639169 | 0.4010371442354076 | 0.009964230583695128 | 0.002326015436565364 | 6.910178485287022E-5 | 0.002668439459720212 | 0.013110829715388326 | 2.0915629522431255E-4 | 0.0021532609744331884 | 0.07928195851423057 | 0.012802339604438011 | 0.24339869753979737 | 2.4679208876025084E-5 | 0.0017984973468403278 | 0.007280366618427399 | 0.006108104196816208 | 8.853666184273998E-5 | 33.66071428571429 |
WT_2 | 0.6791438008130081 | 0.5166692073170732 | 0.5394156504065041 | 0.03476956300813008 | 0.1091829268292683 | 0.0034119664634146346 | 0.34769563008130083 | 0.008741133130081302 | 0.0019724415650406507 | 4.2568343495934966E-5 | 0.002167411077235772 | 0.009456021341463415 | 3.346976626016261E-4 | 0.0032494918699186993 | 0.09715980691056911 | 0.01738478150406504 | 0.26223399390243907 | 5.816590447154473E-6 | 0.0029440396341463416 | 0.00812372967479675 | 0.0058490853658536585 | 2.4566158536585365E-6 | 46.33587786259542 |
WT_3 | 0.6320639534883721 | 0.505031492248062 | 0.4802446705426357 | 0.03346220930232558 | 0.11278003875968992 | 0.0030270906007751936 | 0.33152374031007753 | 0.007621947674418605 | 0.001629733527131783 | 4.9263808139534884E-5 | 0.002051109496124031 | 0.009821778100775194 | 2.0356177325581398E-4 | 0.0019922407945736436 | 0.07312112403100775 | 0.011370954457364343 | 0.23361579457364343 | 2.6026162790697675E-5 | 0.0016204384689922481 | 0.006382606589147287 | 0.005793919573643411 | 8.024733527131784E-5 | 33.08176100628931 |
WT_4 | 0.5306163069544364 | 0.4662062350119904 | 0.4539376498800959 | 0.03159160671462829 | 0.08649352517985609 | 0.0030579448441246998 | 0.28831175059952036 | 0.007821223021582733 | 0.0014262230215827335 | 4.140647482014388E-5 | 0.0015489088729016783 | 0.007514508393285371 | 1.9629736211031174E-4 | 0.0017973477218225415 | 0.0736115107913669 | 0.010060239808153477 | 0.21285995203836927 | 4.6927338129496395E-4 | 1.1992541966426857E-4 | 0.0046313908872901675 | 0.005520863309352517 | 3.588561151079136E-6 | 34.44444444444444 |
WT_5 | 0.6838680229525298 | 0.5237428273343766 | 0.6038054251434533 | 0.04069848721961397 | 0.1270993740219092 | 0.0034360198226395405 | 0.36695357329160144 | 0.009841027647365674 | 0.002418557642149191 | 6.505086071987479E-5 | 0.0022350808555033903 | 0.011175404277516952 | 2.1716979655712047E-4 | 0.002218401147626499 | 0.08840245174752216 | 0.013377125717266559 | 0.2682097026604069 | 5.1707094418362016E-5 | 0.0020649478351591026 | 0.006905399061032862 | 0.0066051643192488255 | 3.9364110589462694E-7 | 37.17948717948718 |
KO4_1 | 0.47047683923705724 | 0.06534400544959128 | 0.10309831970935512 | 0.005895481380563124 | 0.022681630336058127 | 0.002056158038147139 | 0.12952633969118982 | 0.02494688919164396 | 0.058954813805631244 | 2.744448228882834E-4 | 0.0013998138056312442 | 0.005314645776566758 | 1.4462806539509534E-4 | 8.886784741144413E-4 | 0.020242120799273386 | 0.008857742960944595 | 0.16757107175295183 | 1.5043642143505902E-5 | 0.0021490917347865577 | 0.006505358764759309 | 0.005459854677565849 | 7.579904632152588E-7 | 214.8148148148148 |
KO4_2 | 0.43887254901960776 | 0.06165114379084966 | 0.0911705473856209 | 0.0056948937908496726 | 0.01904393382352941 | 0.0017110804738562089 | 0.11886131535947711 | 0.021159926470588234 | 0.05512030228758169 | 2.4085743464052282E-4 | 0.0014655208333333332 | 0.005355290032679738 | 1.159877450980392E-4 | 9.535028594771241E-4 | 0.025992749183006533 | 0.009587275326797385 | 0.1841697303921568 | 1.9958251633986927E-5 | 0.0019305167483660128 | 0.006478594771241829 | 0.00593000408496732 | 2.408574346405228E-6 | 228.85032537960956 |
KO4_3 | 0.351405540417802 | 0.060116485013623974 | 0.0842211625794732 | 0.0049661444141689375 | 0.017541235240690282 | 0.0014462806539509536 | 0.10600249772933695 | 0.01771548592188919 | 0.046466848319709354 | 2.1287624886466848E-4 | 0.0012429881925522252 | 0.005372729336966394 | 8.393074477747501E-5 | 6.737693006357856E-4 | 0.020242120799273386 | 0.006563442325158946 | 0.17076566757493186 | 1.3184968210717529E-5 | 0.0016844232515894639 | 0.005111353315168029 | 0.006011648501362397 | 5.517938237965486E-6 | 218.28103683492498 |
KO4_4 | 0.41449074074074066 | 0.05867466329966329 | 0.08532049663299662 | 0.006271191077441077 | 0.017279419191919186 | 0.0014318771043771042 | 0.09124179292929292 | 0.01628356481481481 | 0.04440972222222222 | 2.325454545454545E-4 | 0.001243472222222222 | 0.004710122053872053 | 1.3834301346801346E-4 | 0.0010523758417508417 | 0.028529882154882148 | 0.009850883838383838 | 0.20643792087542084 | 9.662478956228954E-6 | 0.0020159322390572386 | 0.007616940235690234 | 0.0061635311447811435 | 3.1759680134680126E-7 | 190.97222222222226 |
KO4_5 | 0.37263067694944296 | 0.06164845758354755 | 0.09863753213367607 | 0.005890852613538987 | 0.02019329477292202 | 0.0017069772922022276 | 0.11918701799485858 | 0.02011109682947729 | 0.05342866323907454 | 2.794730077120822E-4 | 0.0014329841473864607 | 0.006219644387317908 | 1.1041923736075405E-4 | 8.521186803770349E-4 | 0.022029048843187654 | 0.008575985432733503 | 0.18686332476435302 | 1.4329841473864607E-5 | 0.0014357240788346183 | 0.006740231362467865 | 0.006548436161096828 | 1.148031276778063E-6 | 191.1764705882353 |
KO9_1 | 0.4113048855905999 | 0.10480364873222017 | 0.05418150896722326 | 0.006604607297464441 | 0.018192331478045765 | 0.0012339146567717997 | 0.05497247990105134 | 0.015423933209647496 | 0.05141311069882499 | 2.1039826839826844E-4 | 0.0014712059369202228 | 0.005853184910327768 | 1.4672510822510824E-4 | 0.001328831168831169 | 0.019181045145330863 | 0.01206230674087817 | 0.20011564625850342 | 2.8870439084724803E-5 | 0.002155395794681509 | 0.006050927643784787 | 0.005892733457019172 | 4.310791589363018E-5 | 244.36090225563908 |
KO9_2 | 0.41118443316412856 | 0.10928849407783417 | 0.06600592216582064 | 0.008007275803722505 | 0.018034404963338975 | 0.0012371601804850535 | 0.05518527918781726 | 0.016086689227298365 | 0.061316976875352515 | 2.315617597292724E-4 | 0.0015689932318104906 | 0.005879216018048505 | 2.405789622109419E-4 | 0.0015401381838691483 | 0.026113818386914834 | 0.01583420755781162 | 0.2459892836999436 | 2.604168076706148E-5 | 0.0026077749576988154 | 0.0076465877044557245 | 0.006708798646362098 | 1.4968556119571348E-6 | 264.797507788162 |
KO9_3 | 0.39887014314928426 | 0.1134491308793456 | 0.06473466257668713 | 0.00712735173824131 | 0.019747341513292434 | 0.0011050664621676894 | 0.05558026584867076 | 0.015758640081799592 | 0.05525332310838447 | 2.47495654396728E-4 | 0.001438548057259714 | 0.005688803680981595 | 1.4745117586912067E-4 | 0.0010102530674846626 | 0.015954805725971372 | 0.010167919222903886 | 0.1843957055214724 | 2.3441794478527608E-5 | 0.0016968328220858897 | 0.005198389570552148 | 0.0060157464212678945 | 7.879320040899795E-7 | 223.24966974900929 |
KO9_4 | 0.3945265423242467 | 0.11499378287900525 | 0.06911860353897656 | 0.007523529411764705 | 0.02091908177905308 | 0.0012967384026781443 | 0.06116690578670492 | 0.017096150167384024 | 0.05902606408417024 | 2.6668770923003347E-4 | 0.0016698565279770442 | 0.005994356767097081 | 1.6086896221903393E-4 | 0.001180521281683405 | 0.016086896221903395 | 0.011377044476327114 | 0.18197154471544713 | 1.8564155906264943E-5 | 0.00167903156384505 | 0.005780272596843615 | 0.005749689143950263 | 1.9451076040172162E-6 | 221.33027522935777 |
KO9_5 | 0.347888 | 0.10880026666666666 | 0.0654848 | 0.00951576 | 0.018724559999999998 | 0.00107436 | 0.05388853333333333 | 0.01613245333333333 | 0.05354746666666666 | 2.0191146666666664E-4 | 0.0013744986666666666 | 0.00583224 | 1.1937333333333332E-4 | 0.0010232 | 0.016439413333333333 | 0.010743599999999999 | 0.19167946666666666 | 1.5279786666666664E-5 | 0.001613245333333333 | 0.00532064 | 0.0060027733333333335 | 1.6371199999999999E-6 | 265.2027027027027 |
KO21_1 | 0.6503389830508475 | 0.11756127770534551 | 0.3807540199913082 | 0.00719819643633203 | 0.041410473707083874 | 0.003168318122555411 | 0.22456149500217298 | 0.03057149065623642 | 0.08143133420252065 | 2.945980008691873E-4 | 0.0017258996088657108 | 0.0070314428509343765 | 2.1622381573229034E-4 | 0.001945458496305954 | 0.03835332464146024 | 0.009449369839200349 | 0.17481334202520643 | 2.6319274228596262E-5 | 1.6842112125162973E-4 | 0.006142090395480227 | 0.005419491525423729 | 1.214521946979574E-6 | 276.41509433962267 |
KO21_2 | 0.6008295852073963 | 0.13870214892553723 | 0.3771164417791104 | 0.007190779610194902 | 0.04058795602198901 | 0.002863528235882059 | 0.2083728135932034 | 0.027516716641679158 | 0.08181509245377311 | 2.946621689155422E-4 | 0.0015468165917041478 | 0.007893878060969516 | 1.3614542728635683E-4 | 0.0012495977011494253 | 0.041227136431784106 | 0.00805367316341829 | 0.23617716141929035 | 2.0677486256871565E-5 | 0.0016874362818590704 | 0.006967066466766617 | 0.006168090954522739 | 6.263968015992004E-5 | 277.65726681127984 |
KO21_3 | 0.6001252653927813 | 0.13984819532908707 | 0.35573036093418264 | 0.007983566878980893 | 0.04290488322717623 | 0.0032857537154989385 | 0.23624840764331212 | 0.029327388535031848 | 0.07874946921443737 | 3.122823779193206E-4 | 0.0017759363057324841 | 0.007467622080679406 | 1.564127388535032E-4 | 0.0013007239915074312 | 0.029327388535031848 | 0.007413312101910829 | 0.1632014861995754 | 4.6706581740976646E-4 | 1.0970615711252656E-4 | 0.005811167728237792 | 0.005539617834394906 | 1.6184373673036094E-6 | 252.17391304347828 |
KO21_4 | 0.6481218038121803 | 0.13765155741515572 | 0.32406090190609016 | 0.0069866341236634105 | 0.03835216178521617 | 0.0024111320316132024 | 0.20573407717340766 | 0.024973500697350066 | 0.07908275220827521 | 3.1216875871687577E-4 | 0.001602466294746629 | 0.008086657368665734 | 1.7897675499767545E-4 | 0.0013170548582054854 | 0.041027894002789396 | 0.007729893072989305 | 0.2381401673640167 | 2.693570432357043E-5 | 0.0016084123663412362 | 0.006956903765690375 | 0.006659600185960017 | 1.5846280799628075E-6 | 253.33333333333337 |
KO21_5 | 0.5538976377952756 | 0.14406933508311462 | 0.3860498687664041 | 0.008308464566929134 | 0.0428011811023622 | 0.0031611329833770773 | 0.2221185476815398 | 0.028534120734908134 | 0.07776946631671042 | 3.3289807524059493E-4 | 0.0016644903762029746 | 0.007469225721784777 | 1.594553805774278E-4 | 0.001499440069991251 | 0.035527777777777776 | 0.007693022747156605 | 0.20421478565179352 | 1.4239085739282589E-5 | 0.002109286964129484 | 0.006574037620297462 | 0.006154418197725284 | 1.5833639545056868E-6 | 233.61344537815128 |
area ratio / mg protein - outliers excluded | |||||||||||||||||||||||
Acylcarnitine chain-length: | C0 | C2:0 | C3:0 | C4:0 | C5:1 | C5:0 | C6:0 | C8:0 | C10:0 | C12:1 | C12:0 | C14:2 | C14:1 | C14:0 | C16:1 | C16:0 | C18:1-OH | C18:2 | C18:1 | C18:0 | C7-DC | C8/C10 | |
Group | Carnitine | Acetylcarnitine | Propionyl carnitine | Malonyl carnitine | Butyrylcarnitine | Tiglylcarnitine | 2-Methylbutyroylcarnitine | Hexanoylcarnitine | Octanoylcarnitine | Decanoylcarnitine | Dodecenoylcarnitine | Lauroylcarnitine | Tetradecadienylcarnitine | Tetradecenoylcarnitine | Myristoylcarnitine | Hexadecenoylcarnitine | Palmitoylcarnitine | Hydroxyoctadecenoylcarnitine | Linoleylcarnitine | Oleoylcarnitine | Stearoylcarnitine | Pimelylcarnitine | |
WT_1 | 0.8236685962373371 | 0.5306029908345392 | 0.6817631452001929 | 0.041337674867342016 | 0.13542715870718763 | 0.004102918475639169 | 0.4010371442354076 | 0.009964230583695128 | 0.002326015436565364 | 6.910178485287022E-5 | 0.002668439459720212 | 0.013110829715388326 | 2.0915629522431255E-4 | 0.0021532609744331884 | 0.07928195851423057 | 0.012802339604438011 | 0.24339869753979737 | 2.4679208876025084E-5 | 0.0017984973468403278 | 0.007280366618427399 | 0.006108104196816208 | 8.853666184273998E-5 | 33.66071428571429 |
WT_2 | 0.6791438008130081 | 0.5166692073170732 | 0.5394156504065041 | 0.03476956300813008 | 0.1091829268292683 | 0.0034119664634146346 | 0.34769563008130083 | 0.008741133130081302 | 0.0019724415650406507 | 4.2568343495934966E-5 | 0.002167411077235772 | 0.009456021341463415 | 3.346976626016261E-4 | 0.0032494918699186993 | 0.09715980691056911 | 0.01738478150406504 | 0.26223399390243907 | 5.816590447154473E-6 | 0.0029440396341463416 | 0.00812372967479675 | 0.0058490853658536585 | 2.4566158536585365E-6 | 46.33587786259542 |
WT_3 | 0.6320639534883721 | 0.505031492248062 | 0.4802446705426357 | 0.03346220930232558 | 0.11278003875968992 | 0.0030270906007751936 | 0.33152374031007753 | 0.007621947674418605 | 0.001629733527131783 | 4.9263808139534884E-5 | 0.002051109496124031 | 0.009821778100775194 | 2.0356177325581398E-4 | 0.0019922407945736436 | 0.07312112403100775 | 0.011370954457364343 | 0.23361579457364343 | 2.6026162790697675E-5 | 0.0016204384689922481 | 0.006382606589147287 | 0.005793919573643411 | 8.024733527131784E-5 | 33.08176100628931 |
WT_4 | 0.5306163069544364 | 0.4662062350119904 | 0.4539376498800959 | 0.03159160671462829 | 0.08649352517985609 | 0.0030579448441246998 | 0.28831175059952036 | 0.007821223021582733 | 0.0014262230215827335 | 4.140647482014388E-5 | 0.0015489088729016783 | 0.007514508393285371 | 1.9629736211031174E-4 | 0.0017973477218225415 | 0.0736115107913669 | 0.010060239808153477 | 0.21285995203836927 | 0.0046313908872901675 | 0.005520863309352517 | 3.588561151079136E-6 | 34.44444444444444 | ||
WT_5 | 0.6838680229525298 | 0.5237428273343766 | 0.6038054251434533 | 0.04069848721961397 | 0.1270993740219092 | 0.0034360198226395405 | 0.36695357329160144 | 0.009841027647365674 | 0.002418557642149191 | 6.505086071987479E-5 | 0.0022350808555033903 | 0.011175404277516952 | 2.1716979655712047E-4 | 0.002218401147626499 | 0.08840245174752216 | 0.013377125717266559 | 0.2682097026604069 | 5.1707094418362016E-5 | 0.0020649478351591026 | 0.006905399061032862 | 0.0066051643192488255 | 3.9364110589462694E-7 | 37.17948717948718 |
KO4_1 | 0.47047683923705724 | 0.06534400544959128 | 0.10309831970935512 | 0.005895481380563124 | 0.022681630336058127 | 0.002056158038147139 | 0.12952633969118982 | 0.02494688919164396 | 0.058954813805631244 | 2.744448228882834E-4 | 0.0013998138056312442 | 0.005314645776566758 | 1.4462806539509534E-4 | 8.886784741144413E-4 | 0.020242120799273386 | 0.008857742960944595 | 0.16757107175295183 | 1.5043642143505902E-5 | 0.0021490917347865577 | 0.006505358764759309 | 0.005459854677565849 | 7.579904632152588E-7 | 214.8148148148148 |
KO4_2 | 0.43887254901960776 | 0.06165114379084966 | 0.0911705473856209 | 0.0056948937908496726 | 0.01904393382352941 | 0.0017110804738562089 | 0.11886131535947711 | 0.021159926470588234 | 0.05512030228758169 | 2.4085743464052282E-4 | 0.0014655208333333332 | 0.005355290032679738 | 1.159877450980392E-4 | 9.535028594771241E-4 | 0.025992749183006533 | 0.009587275326797385 | 0.1841697303921568 | 1.9958251633986927E-5 | 0.0019305167483660128 | 0.006478594771241829 | 0.00593000408496732 | 2.408574346405228E-6 | 228.85032537960956 |
KO4_3 | 0.351405540417802 | 0.060116485013623974 | 0.0842211625794732 | 0.0049661444141689375 | 0.017541235240690282 | 0.0014462806539509536 | 0.10600249772933695 | 0.01771548592188919 | 0.046466848319709354 | 2.1287624886466848E-4 | 0.0012429881925522252 | 0.005372729336966394 | 8.393074477747501E-5 | 6.737693006357856E-4 | 0.020242120799273386 | 0.006563442325158946 | 0.17076566757493186 | 1.3184968210717529E-5 | 0.0016844232515894639 | 0.005111353315168029 | 0.006011648501362397 | 5.517938237965486E-6 | 218.28103683492498 |
KO4_4 | 0.41449074074074066 | 0.05867466329966329 | 0.08532049663299662 | 0.006271191077441077 | 0.017279419191919186 | 0.0014318771043771042 | 0.09124179292929292 | 0.01628356481481481 | 0.04440972222222222 | 2.325454545454545E-4 | 0.001243472222222222 | 0.004710122053872053 | 1.3834301346801346E-4 | 0.0010523758417508417 | 0.028529882154882148 | 0.009850883838383838 | 0.20643792087542084 | 9.662478956228954E-6 | 0.0020159322390572386 | 0.007616940235690234 | 0.0061635311447811435 | 3.1759680134680126E-7 | 190.97222222222226 |
KO4_5 | 0.37263067694944296 | 0.06164845758354755 | 0.09863753213367607 | 0.005890852613538987 | 0.02019329477292202 | 0.0017069772922022276 | 0.11918701799485858 | 0.02011109682947729 | 0.05342866323907454 | 2.794730077120822E-4 | 0.0014329841473864607 | 0.006219644387317908 | 1.1041923736075405E-4 | 8.521186803770349E-4 | 0.022029048843187654 | 0.008575985432733503 | 0.18686332476435302 | 1.4329841473864607E-5 | 0.0014357240788346183 | 0.006740231362467865 | 0.006548436161096828 | 1.148031276778063E-6 | 191.1764705882353 |
KO9_1 | 0.4113048855905999 | 0.10480364873222017 | 0.05418150896722326 | 0.006604607297464441 | 0.018192331478045765 | 0.0012339146567717997 | 0.05497247990105134 | 0.015423933209647496 | 0.05141311069882499 | 2.1039826839826844E-4 | 0.0014712059369202228 | 0.005853184910327768 | 1.4672510822510824E-4 | 0.001328831168831169 | 0.019181045145330863 | 0.01206230674087817 | 0.20011564625850342 | 2.8870439084724803E-5 | 0.002155395794681509 | 0.006050927643784787 | 0.005892733457019172 | 4.310791589363018E-5 | 244.36090225563908 |
KO9_2 | 0.41118443316412856 | 0.10928849407783417 | 0.06600592216582064 | 0.008007275803722505 | 0.018034404963338975 | 0.0012371601804850535 | 0.05518527918781726 | 0.016086689227298365 | 0.061316976875352515 | 2.315617597292724E-4 | 0.0015689932318104906 | 0.005879216018048505 | 2.405789622109419E-4 | 0.0015401381838691483 | 0.026113818386914834 | 0.01583420755781162 | 0.2459892836999436 | 2.604168076706148E-5 | 0.0026077749576988154 | 0.0076465877044557245 | 0.006708798646362098 | 1.4968556119571348E-6 | 264.797507788162 |
KO9_3 | 0.39887014314928426 | 0.1134491308793456 | 0.06473466257668713 | 0.00712735173824131 | 0.019747341513292434 | 0.0011050664621676894 | 0.05558026584867076 | 0.015758640081799592 | 0.05525332310838447 | 2.47495654396728E-4 | 0.001438548057259714 | 0.005688803680981595 | 1.4745117586912067E-4 | 0.0010102530674846626 | 0.015954805725971372 | 0.010167919222903886 | 0.1843957055214724 | 2.3441794478527608E-5 | 0.0016968328220858897 | 0.005198389570552148 | 0.0060157464212678945 | 7.879320040899795E-7 | 223.24966974900929 |
KO9_4 | 0.3945265423242467 | 0.11499378287900525 | 0.06911860353897656 | 0.007523529411764705 | 0.02091908177905308 | 0.0012967384026781443 | 0.06116690578670492 | 0.017096150167384024 | 0.05902606408417024 | 2.6668770923003347E-4 | 0.0016698565279770442 | 0.005994356767097081 | 1.6086896221903393E-4 | 0.001180521281683405 | 0.016086896221903395 | 0.011377044476327114 | 0.18197154471544713 | 1.8564155906264943E-5 | 0.00167903156384505 | 0.005780272596843615 | 0.005749689143950263 | 1.9451076040172162E-6 | 221.33027522935777 |
KO9_5 | 0.347888 | 0.10880026666666666 | 0.0654848 | 0.00951576 | 0.018724559999999998 | 0.00107436 | 0.05388853333333333 | 0.01613245333333333 | 0.05354746666666666 | 2.0191146666666664E-4 | 0.0013744986666666666 | 0.00583224 | 1.1937333333333332E-4 | 0.0010232 | 0.016439413333333333 | 0.010743599999999999 | 0.19167946666666666 | 1.5279786666666664E-5 | 0.001613245333333333 | 0.00532064 | 0.0060027733333333335 | 1.6371199999999999E-6 | 265.2027027027027 |
KO21_1 | 0.6503389830508475 | 0.11756127770534551 | 0.3807540199913082 | 0.00719819643633203 | 0.041410473707083874 | 0.003168318122555411 | 0.22456149500217298 | 0.03057149065623642 | 0.08143133420252065 | 2.945980008691873E-4 | 0.0017258996088657108 | 0.0070314428509343765 | 2.1622381573229034E-4 | 0.001945458496305954 | 0.03835332464146024 | 0.009449369839200349 | 0.17481334202520643 | 2.6319274228596262E-5 | 1.6842112125162973E-4 | 0.006142090395480227 | 0.005419491525423729 | 1.214521946979574E-6 | 276.41509433962267 |
KO21_2 | 0.6008295852073963 | 0.13870214892553723 | 0.3771164417791104 | 0.007190779610194902 | 0.04058795602198901 | 0.002863528235882059 | 0.2083728135932034 | 0.027516716641679158 | 0.08181509245377311 | 2.946621689155422E-4 | 0.0015468165917041478 | 0.007893878060969516 | 1.3614542728635683E-4 | 0.0012495977011494253 | 0.041227136431784106 | 0.00805367316341829 | 0.23617716141929035 | 2.0677486256871565E-5 | 0.0016874362818590704 | 0.006967066466766617 | 0.006168090954522739 | 6.263968015992004E-5 | 277.65726681127984 |
KO21_3 | 0.6001252653927813 | 0.13984819532908707 | 0.35573036093418264 | 0.007983566878980893 | 0.04290488322717623 | 0.0032857537154989385 | 0.23624840764331212 | 0.029327388535031848 | 0.07874946921443737 | 3.122823779193206E-4 | 0.0017759363057324841 | 0.007467622080679406 | 1.564127388535032E-4 | 0.0013007239915074312 | 0.029327388535031848 | 0.007413312101910829 | 0.1632014861995754 | 0.005811167728237792 | 0.005539617834394906 | 1.6184373673036094E-6 | 252.17391304347828 | ||
KO21_4 | 0.6481218038121803 | 0.13765155741515572 | 0.32406090190609016 | 0.0069866341236634105 | 0.03835216178521617 | 0.0024111320316132024 | 0.20573407717340766 | 0.024973500697350066 | 0.07908275220827521 | 3.1216875871687577E-4 | 0.001602466294746629 | 0.008086657368665734 | 1.7897675499767545E-4 | 0.0013170548582054854 | 0.041027894002789396 | 0.007729893072989305 | 0.2381401673640167 | 2.693570432357043E-5 | 0.0016084123663412362 | 0.006956903765690375 | 0.006659600185960017 | 1.5846280799628075E-6 | 253.33333333333337 |
KO21_5 | 0.5538976377952756 | 0.14406933508311462 | 0.3860498687664041 | 0.008308464566929134 | 0.0428011811023622 | 0.0031611329833770773 | 0.2221185476815398 | 0.028534120734908134 | 0.07776946631671042 | 3.3289807524059493E-4 | 0.0016644903762029746 | 0.007469225721784777 | 1.594553805774278E-4 | 0.001499440069991251 | 0.035527777777777776 | 0.007693022747156605 | 0.20421478565179352 | 1.4239085739282589E-5 | 0.002109286964129484 | 0.006574037620297462 | 0.006154418197725284 | 1.5833639545056868E-6 | 233.61344537815128 |
Mean per clone | |||||||||||||||||||||||
Acylcarnitine chain-length: | C0 | C2:0 | C3:0 | Malonyl carnitine | C4:0 | C5:1 | C5:0 | C6:0 | C8:0 | C10:0 | C12:1 | C12:0 | C14:2 | C14:1 | C14:0 | C16:1 | C16:0 | C18:1-OH | C18:2 | C18:1 | C18:0 | C7-DC | C8/C10 |
WT | 0.6698721360891368 | 0.5084505505492083 | 0.5518333082345764 | 0.03637190822240799 | 0.11419660469958223 | 0.0034071880413186475 | 0.34710436770358155 | 0.008797912411428688 | 0.0019545942384939447 | 5.3478254405671746E-5 | 0.0021341899522970167 | 0.010215708365685852 | 2.3217657794983698E-4 | 0.0022821485016749146 | 0.0823153703989393 | 0.012999088218257484 | 0.24406362814293123 | 2.7057264133059814E-5 | 0.002106980821284505 | 0.006664698566138894 | 0.005975427352982924 | 3.5044563044938024E-5 | 36.940456955706125 |
KO4 | 0.4095752692729301 | 0.06148695102745515 | 0.09248961168822438 | 0.00574371265531236 | 0.019347902673023807 | 0.0016704747125067265 | 0.11296379274083106 | 0.0200433926456827 | 0.05167606997484381 | 2.480393937302023E-4 | 0.0013569558402250971 | 0.005394486317480569 | 1.186617612198754E-4 | 8.840890312710456E-4 | 0.02340718435592462 | 0.008687065976803654 | 0.18316154307196286 | 1.4435836483660783E-5 | 0.0018431376105267783 | 0.006490495689865454 | 0.006022694913954707 | 2.0300262251421675E-6 | 208.8189739679614 |
KO9 | 0.3927548008456519 | 0.11026706464701437 | 0.06390509944974151 | 0.007755704850238592 | 0.019123543946746053 | 0.0011894479404205374 | 0.05615869281151552 | 0.016099573203892565 | 0.056111388286679775 | 2.3161097168419381E-4 | 0.0015046204841268275 | 0.005849560275290989 | 1.629995083715076E-4 | 0.001216588740373677 | 0.01875519576269076 | 0.012037015599584156 | 0.2008303293724066 | 2.24395713806491E-5 | 0.0019504560943289194 | 0.005999363503127254 | 0.006073948200386552 | 9.794986222738903E-6 | 243.7882115449742 |
KO21 | 0.6106626550516963 | 0.13556650289164804 | 0.36474231867541906 | 0.007533528323220073 | 0.0412113311687655 | 0.0029779730177853375 | 0.21940706821872719 | 0.028184643453041124 | 0.07976962287914335 | 3.0932187633230413E-4 | 0.0016631218354503895 | 0.007589765216606761 | 1.6944282348945074E-4 | 0.0014624550234319093 | 0.03709270427776867 | 0.008067854184935075 | 0.20330938853197647 | 2.2042887637080212E-5 | 0.001393389183395355 | 0.006490253195294495 | 0.005988243739605335 | 1.3728126301734345E-5 | 258.63861058117305 |
Replicates vs. mean WT | |||||||||||||||||||||||
Acylcarnitine chain-length: | C0 | C2:0 | C3:0 | Malonyl carnitine | C4:0 | C5:1 | C5:0 | C6:0 | C8:0 | C10:0 | C12:1 | C12:0 | C14:2 | C14:1 | C14:0 | C16:1 | C16:0 | C18:1-OH | C18:2 | C18:1 | C18:0 | C7-DC | C8/C10 |
WT_1 | 1.2295907709284617 | 1.0435685245328237 | 1.2354512404865294 | 1.1365275259843177 | 1.1859123050414393 | 1.2041949037985178 | 1.155379135355287 | 1.132567604418449 | 1.1900247073058023 | 1.2921473526170573 | 1.2503289394874084 | 1.2833989818490774 | 0.900850107582781 | 0.9435236019272484 | 0.9631489007459072 | 0.984864429680296 | 0.9972755850259488 | 0.9121102841240659 | 0.8535898042697359 | 1.092377479068072 | 1.0222037414222853 | 2.5264022190605844 | 0.9209667186142352 |
WT_2 | 1.0138409469872882 | 1.0161641220743836 | 0.9774974477930684 | 0.9559455279475622 | 0.956096086363483 | 1.0014024532952217 | 1.0017034138222778 | 0.9935462779472971 | 1.0091309624244353 | 0.7959935111760172 | 1.0155661518802483 | 0.925635404121931 | 1.4415651464806212 | 1.4238739799508366 | 1.1803361442666982 | 1.3373846851541298 | 1.07444929790549 | 0.21497334019249545 | 1.3972788002652679 | 1.2189192945755574 | 0.9788564098154091 | 0.07009977126860995 | 1.26776279989208 |
WT_3 | 0.9435591054413798 | 0.9932755342727957 | 0.8702712637608504 | 0.9200014774509465 | 0.9875953760304969 | 0.888442482207014 | 0.9551125573654277 | 0.8663359349335555 | 0.8337963425020256 | 0.9211932716769848 | 0.9610716674569821 | 0.9614387714674928 | 0.8767541284883379 | 0.8729672031033467 | 0.8883046225343836 | 0.8747501568143531 | 0.9571921730051098 | 0.9618918846601977 | 0.7690807873630099 | 0.9576737080916425 | 0.9696243015574602 | 2.289865482654636 | 0.9051263921892768 |
WT_4 | 0.7921158059391648 | 0.9169155869895563 | 0.8225992217329757 | 0.8685716053568326 | 0.7574089037707835 | 0.8974981148798632 | 0.8306197715314587 | 0.8889862339869157 | 0.729677287231578 | 0.7742675089213913 | 0.7257596125567907 | 0.7355836839005995 | 0.8454658253802106 | 0.7875682588155117 | 0.8942620367813523 | 0.7739188810199522 | 0.8721494212718656 | 0.6949137821207274 | 0.9239277767466305 | 0.10239993994153916 | 0.9424097987116486 | ||
WT_5 | 1.020893370703705 | 1.0300762321304406 | 1.0941808262265753 | 1.1189538632603406 | 1.1129873287937972 | 1.0084620458193831 | 1.057185121925549 | 1.118563948713783 | 1.2373707005361583 | 1.2163983556085498 | 1.0472736286185704 | 1.0939431586608992 | 0.9353647920680491 | 0.972066956203056 | 1.0739482956716586 | 1.02908184733127 | 1.0989335227915853 | 1.9110244910232408 | 0.9800506081019869 | 1.036115736144 | 1.1053877704582147 | 0.011232587074629999 | 1.017241346003889 |
KO4_1 | 0.7023382730677621 | 0.12851594983820797 | 0.186828736451569 | 0.16208886661962482 | 0.19861913054006153 | 0.6034765364318918 | 0.37316251751058943 | 2.8355464370431087 | 30.16217516892772 | 5.131895682428568 | 0.6558993514727367 | 0.5202425114658163 | 0.6229227197342146 | 0.3894043150400696 | 0.24590936906643893 | 0.6814126354265151 | 0.6865876453119717 | 0.5559927296982287 | 1.019986377225959 | 0.9760919717826194 | 0.9137178573245138 | 0.021629331267257617 | 5.877394443578025 |
KO4_2 | 0.6551586868231956 | 0.12125297872970443 | 0.16521392606273344 | 0.1565739624114955 | 0.16676444867716 | 0.5021972527216279 | 0.34243681848734814 | 2.405107652936054 | 28.200381031539838 | 4.503838753102199 | 0.686687158167904 | 0.5242211152647954 | 0.4995669508192122 | 0.4178092962738092 | 0.31577029972693255 | 0.7375344459415132 | 0.7545971998920761 | 0.7376300699079554 | 0.9162478978755431 | 0.9720761872348442 | 0.9923983231102409 | 0.06872890220707524 | 6.261410005434962 |
KO4_3 | 0.5245859940814765 | 0.11823467385115133 | 0.15262065794635213 | 0.13653791227564457 | 0.15360557598744837 | 0.42447925867666964 | 0.3053908495322088 | 2.0136010786918463 | 23.77314299028786 | 3.980613264783217 | 0.5824168515152103 | 0.5259282219736394 | 0.36149531325941375 | 0.2952346440826672 | 0.24590936906643893 | 0.5049155921521062 | 0.699676837856914 | 0.4872986472644707 | 0.7994487821500758 | 0.7669294064006296 | 1.0060616833307148 | 0.15745490194555356 | 5.972231264114661 |
KO4_4 | 0.6187609819996847 | 0.11539895715775157 | 0.1546128067295425 | 0.17241853353125763 | 0.15131289793927122 | 0.42025185784079594 | 0.2628655857399384 | 1.8508441609014077 | 22.720686139155323 | 4.348411464245388 | 0.5826436493545852 | 0.4610666128345207 | 0.5958525820718369 | 0.4611338135877144 | 0.34659240451221707 | 0.7578134460652456 | 0.8458364830769638 | 0.35711219392735616 | 0.9567871803542288 | 1.1428784302998132 | 1.0314795546304012 | 0.009062655480667384 | 5.225054327534345 |
KO4_5 | 0.556271349223367 | 0.1212476956057129 | 0.178745158477724 | 0.16196160447555932 | 0.1768292045638717 | 0.5009929805757344 | 0.34337516057026773 | 2.285894185915345 | 27.33491288721 | 5.22591866204298 | 0.671441708290374 | 0.6088314353422069 | 0.4755830167529247 | 0.37338441374505116 | 0.26761768472187447 | 0.6597374591772027 | 0.7656336431044124 | 0.5296116193933941 | 0.6814129793356828 | 1.011333265200129 | 1.0958941970615472 | 0.03275918365156758 | 5.230642620932777 |
KO9_1 | 0.6140050666861436 | 0.20612358196685085 | 0.0981845571093934 | 0.18158539434000545 | 0.1593071136038103 | 0.3621504424787341 | 0.15837449774759524 | 1.7531355722081816 | 26.30372569727815 | 3.934277039079163 | 0.6893509808425309 | 0.5729592800425253 | 0.6319548230089299 | 0.5822719984505448 | 0.23301899818187571 | 0.9279348319166274 | 0.8199322766000573 | 1.0670125014394773 | 1.022978364543199 | 0.9079071744561005 | 0.9861610072252872 | 1.2300885543458606 | 6.685783801192269 |
KO9_2 | 0.6138252526291289 | 0.21494419459234537 | 0.11961206614545723 | 0.22015000573407875 | 0.1579241783132012 | 0.36310299445822447 | 0.15898756778233372 | 1.8284666265148755 | 31.370693552539333 | 4.330017168711357 | 0.7351703769956334 | 0.575507425192026 | 1.0361896291835273 | 0.6748632627275614 | 0.3172410967763966 | 1.218101400032977 | 1.007889973494472 | 0.962465408143115 | 1.2376832913500395 | 1.1473268638593022 | 1.1227311872535903 | 0.04271291983403248 | 7.244935142341588 |
KO9_3 | 0.5954422070426415 | 0.2231271669522283 | 0.11730836397640816 | 0.19595759712849747 | 0.17292406867298635 | 0.3243338638098786 | 0.16012551560899665 | 1.7911794690441294 | 28.26843649705951 | 4.627968080620062 | 0.6740487442138937 | 0.5568682540008733 | 0.6350820447572377 | 0.4426763055704822 | 0.1938253530130135 | 0.7822024939120604 | 0.7555230860269132 | 0.8663771164463498 | 0.8053385227547674 | 0.7799887000086438 | 1.0067474786158757 | 0.02248371603548333 | 6.108174474114365 |
KO9_4 | 0.5889579832766009 | 0.22616512609691047 | 0.12525268501841724 | 0.20685000538766377 | 0.18318479637888577 | 0.3805890332299598 | 0.1762205016069977 | 1.9432053159765192 | 30.198627889976308 | 4.986843946083426 | 0.782431070008453 | 0.5867783762535628 | 0.6928733451045633 | 0.517285041186845 | 0.19543004112037243 | 0.8752186526704099 | 0.7455905908637848 | 0.6861061715246517 | 0.7968898183047728 | 0.8672969286579963 | 0.9622222486028597 | 0.05550383383359592 | 6.055659294029793 |
KO9_5 | 0.5193349316349354 | 0.21398396864581007 | 0.11866771907897111 | 0.2616238868143172 | 0.1639677471082334 | 0.3153216044935993 | 0.15525167167977785 | 1.833668327088243 | 27.39569451914792 | 3.775580727355463 | 0.6440376430351484 | 0.5709090149431297 | 0.5141489050593405 | 0.4483494388069194 | 0.1997125598009235 | 0.8264887367185026 | 0.7853667837569522 | 0.5647203128714375 | 0.765666833336352 | 0.798331679549979 | 1.0045764057924256 | 0.0467153777292273 | 7.256021390472754 |
KO21_1 | 0.9708404753893359 | 0.2312147711874054 | 0.6899801340542769 | 0.19790538325116988 | 0.3626243863906697 | 0.9298923581949444 | 0.646956696303928 | 3.474857355538498 | 41.66150324134035 | 5.508743771523386 | 0.8086907198715535 | 0.6882971399763825 | 0.9312903895887668 | 0.852467968179171 | 0.46593150775586445 | 0.7269255874368571 | 0.7162613428119258 | 0.9727248881914177 | 0.07993481456986071 | 0.9215856252953638 | 0.9069630011848989 | 0.03465650136433944 | 7.562795615345764 |
KO21_2 | 0.8969317468781037 | 0.27279378255312464 | 0.6833883278731041 | 0.19770146691849425 | 0.3554217406792786 | 0.8404373932862884 | 0.6003174635104234 | 3.1276415761919063 | 41.85783977180519 | 5.509943661966109 | 0.7247792494006065 | 0.7727195979365201 | 0.5863874318785584 | 0.547553193945232 | 0.5008437213120449 | 0.6195567741518011 | 0.9676868414042329 | 0.7642120117978543 | 0.8008788047868123 | 1.0453685785826763 | 1.0322426481251816 | 1.787429339027469 | 7.596781807541946 |
KO21_3 | 0.8958803226186519 | 0.27504778031615573 | 0.6446337247605336 | 0.21949815858334262 | 0.37571067318548035 | 0.9643593707341401 | 0.6806264329265437 | 3.3334485686553217 | 40.28942051682065 | 5.83942728478813 | 0.8321360073038737 | 0.7309940547796807 | 0.6736800939813018 | 0.5699558948739768 | 0.35628083057753884 | 0.570294775867332 | 0.6686841765049872 | 0.8719325668774269 | 0.9270663849054306 | 0.04618226699611776 | 6.899549998982899 | ||
KO21_4 | 0.9675306209869547 | 0.27072752161733316 | 0.5872441860075914 | 0.19208874279956223 | 0.33584327560446703 | 0.7076603939593682 | 0.5927153222949342 | 2.8385711893322467 | 40.45993314152512 | 5.837302697818949 | 0.7508545774109299 | 0.7915904682467725 | 0.7708648158142134 | 0.5771118125042575 | 0.4984232446983932 | 0.5946488663822216 | 0.9757298503509684 | 0.9955073133450748 | 0.7633730454939214 | 1.0438437232609556 | 1.1144977241896439 | 0.04521751570795223 | 6.93127206794374 |
KO21_5 | 0.826870693605878 | 0.28334974743855934 | 0.699576961023708 | 0.22843081303637675 | 0.3748025715384407 | 0.927783540280817 | 0.6399186191492222 | 3.2432831108709 | 39.78803619959169 | 6.224924110561259 | 0.7799166959864529 | 0.7311510327442003 | 0.6867849547333712 | 0.6570300174992039 | 0.43160563580766664 | 0.5918124885368189 | 0.8367276484646824 | 0.5262574098127171 | 1.0010945248393732 | 0.986396842266498 | 1.029954484285213 | 0.0451814437656227 | 6.39173032360137 |
Acylcarnitine chain-length: | Mean Clone vs. mean WT (for WT, this should be 1 everywhere) | ||||||||||||||||||||||
C0 | C2:0 | C3:0 | Malonyl carnitine | C4:0 | C5:1 | C5:0 | C6:0 | C8:0 | C10:0 | C12:1 | C12:0 | C14:2 | C14:1 | C14:0 | C16:1 | C16:0 | C18:1-OH | C18:2 | C18:1 | C18:0 | C7-DC | C8/C10 | |
WT | 0.9999999999999998 | 1 | 0.9999999999999998 | 1 | 1 | 1 | 1 | 1 | 0.9999999999999998 | 1 | 1 | 1 | 1 | 0.9999999999999998 | 1 | 1.0000000000000002 | 1 | 1 | 1.0000000000000002 | 1 | 1 | 0.9999999999999998 | 1.0107014110822259 |
KO4 | 0.6114230570390972 | 0.12093005103650563 | 0.1676042571335842 | 0.15791617586271636 | 0.1694262515415626 | 0.4902795772493439 | 0.32544618636807054 | 2.2781987030975523 | 26.438259643424146 | 4.6381355653204706 | 0.635817743760162 | 0.5280579793761957 | 0.5110841165275204 | 0.3873932965458623 | 0.28435982541878035 | 0.6682827157525166 | 0.7504663618484676 | 0.5335290520382809 | 0.8747766433882977 | 0.973861852183607 | 1.0079103230914837 | 0.05792699491042428 | 5.713346532318954 |
KO9 | 0.5863130882538901 | 0.21686880765082903 | 0.11580507826572943 | 0.2132333778809125 | 0.1674615808154234 | 0.3490995876940792 | 0.16179195088514026 | 1.82993106216639 | 28.707435631200248 | 4.330937392369894 | 0.7050077630191319 | 0.5726044700864235 | 0.7020497494227197 | 0.5330892093484706 | 0.22784560977851634 | 0.9259892230501154 | 0.8228605421484361 | 0.8293363020850062 | 0.9257113660578261 | 0.9001702693064043 | 1.0164876654980077 | 0.2795008803556399 | 6.670114820430153 |
KO21 | 0.9116107718957848 | 0.26662672062251563 | 0.6609646667438428 | 0.20712491291778914 | 0.3608805294796672 | 0.8740266112911117 | 0.6321069068370104 | 3.2035603601177742 | 40.8113465742166 | 5.784068305331568 | 0.7792754499946833 | 0.7429504587367112 | 0.7298015371992423 | 0.6408237774003682 | 0.4506169880303016 | 0.6206476984750061 | 0.8330179719073595 | 0.814675405786766 | 0.6613202974224919 | 0.9738254672565843 | 1.0021448485380735 | 0.39173341337230017 | 7.076425962683144 |
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area ratio / mg protein | |||||||||||||||||||||||
C0 | C2:0 | C3:0 | C4:0 | C5:1 | C5:0 | C6:0 | C8:0 | C10:0 | C12:1 | C12:0 | C14:2 | C14:1 | C14:0 | C16:1 | C16:0 | C18:1-OH | C18:2 | C18:1 | C18:0 | C7-DC | C8/C10 | ||
Group | Carnitine | Acetylcarnitine | Propionyl carnitine | Malonyl carnitine | Butyrylcarnitine | Tiglylcarnitine | 2-Methylbutyroylcarnitine | Hexanoylcarnitine | Octanoylcarnitine | Decanoylcarnitine | Dodecenoylcarnitine | Lauroylcarnitine | Tetradecadienylcarnitine | Tetradecenoylcarnitine | Myristoylcarnitine | Hexadecenoylcarnitine | Palmitoylcarnitine | Hydroxyoctadecenoylcarnitine | Linoleylcarnitine | Oleoylcarnitine | Stearoylcarnitine | Pimelylcarnitine | |
WT_1 | 0.6834080841638979 | 0.40721207087486144 | 0.4142940199335547 | 0.02057306201550387 | 0.08073421926910297 | 0.002868189368770763 | 0.25105509413067545 | 0.006444573643410851 | 0.0015013732004429674 | 3.0239922480620147E-5 | 0.0010056367663344404 | 0.009560631229235879 | 1.2464230343300106E-4 | 0.0014376356589147284 | 0.06515393133997784 | 0.008179651162790695 | 0.24114036544850495 | 1.6855038759689916E-5 | 0.0016500941306755257 | 0.0042491694352159454 | 0.005276052048726466 | 2.9673366555924687E-6 | 49.648711943793906 |
WT_2 | 0.6800596089651882 | 0.43304244158321403 | 0.487935145445875 | 0.022627992370052454 | 0.09819694802098235 | 0.0034765379113018595 | 0.31715784453981877 | 0.00814241773962804 | 0.0017321697663328563 | 4.5743919885550774E-5 | 0.0013387720553171194 | 0.008843824511206485 | 2.4884692417739623E-4 | 0.002491518836432999 | 0.07502002861230328 | 0.011222508345255124 | 0.22262041010968045 | 4.208440629470672E-4 | 1.3174248927038624E-4 | 0.004543896041964711 | 0.005641750119217929 | 3.476537911301859E-6 | 37.866666666666674 |
WT_3 | 0.6945520520520521 | 0.4641016016016016 | 0.4833058058058058 | 0.024325325325325324 | 0.09442067067067067 | 0.0033287287287287284 | 0.32327077077077077 | 0.008385835835835836 | 0.0017091741741741742 | 3.264714714714715E-5 | 0.0013923048048048046 | 0.00918601101101101 | 1.3827027027027026E-4 | 0.0018083958958958958 | 0.06433408408408409 | 0.009666116116116117 | 0.22340890890890888 | 2.256493993993994E-5 | 1.251473973973974E-4 | 0.004544994994994995 | 0.005729254254254254 | 1.2642767767767768E-6 | 52.35294117647059 |
WT_4 | 0.6936087450312323 | 0.4975099375354912 | 0.5047728563316297 | 0.023604486087450312 | 0.09006019307211811 | 0.0030395315161839864 | 0.2912430437251562 | 0.008098154457694491 | 0.0017213117546848382 | 4.394065871663827E-5 | 0.0012855366269165247 | 0.00976862578080636 | 1.4053747870528108E-4 | 0.0016305252697331061 | 0.06609256104486087 | 0.008969704713231118 | 0.2640070982396366 | 1.1947501419647927E-5 | 0.0019864082907438954 | 0.004720897217490062 | 0.006282424758659852 | 7.335547984099943E-5 | 39.17355371900827 |
WT_5 | 0.6113338338338337 | 0.46410160160160147 | 0.4224924924924924 | 0.022020820820820814 | 0.0905798298298298 | 0.00279101101101101 | 0.29382432432432426 | 0.006785485485485483 | 0.0013666991991991989 | 3.2647147147147136E-5 | 0.0011714564564564562 | 0.008257807807807806 | 1.3090865865865862E-4 | 0.0015907482482482476 | 0.05697247247247245 | 0.00841784284284284 | 0.20964589589589586 | 3.0086586586586575E-5 | 0.0013506956956956953 | 0.004288938938938938 | 0.0055052052052052035 | 1.0050200200200197E-6 | 41.86274509803922 |
KO4_1 | 0.3644546945469454 | 0.07393972939729396 | 0.11458036080360802 | 0.006397621976219761 | 0.021631303813038127 | 0.002073983189831898 | 0.1263792537925379 | 0.02241789667896679 | 0.05296391963919639 | 2.0739831898318982E-4 | 0.0011405596555965557 | 0.0053750512505125045 | 1.022570725707257E-4 | 6.266523165231652E-4 | 0.017331262812628125 | 0.0063189626896268955 | 0.16544669946699464 | 1.7750779007790076E-5 | 0.0015312341123411232 | 0.004903095530955309 | 0.006214083640836407 | 1.7462361623616234E-6 | 255.37294563843236 |
KO4_2 | 0.31455081300813004 | 0.07070894308943089 | 0.09956443089430893 | 0.0061870325203252025 | 0.0190810162601626 | 0.0018249146341463413 | 0.11672174796747965 | 0.0190810162601626 | 0.04679268292682926 | 1.6923353658536582E-4 | 9.956443089430894E-4 | 0.004575284552845528 | 1.25820325203252E-4 | 9.020589430894307E-4 | 0.02456615853658536 | 0.008370691056910568 | 0.18639085365853655 | 2.144664634146341E-5 | 1.4323760162601623E-4 | 0.005875081300813006 | 0.0063430081300813 | 1.2166097560975608E-6 | 276.4976958525346 |
KO4_3 | 0.39113149847094786 | 0.08074071647007423 | 0.08800458715596328 | 0.007040366972477062 | 0.019556574923547395 | 0.001681865443425076 | 0.10700240279598075 | 0.01829936653560506 | 0.048332678025338555 | 1.8606684141546522E-4 | 9.694473569244208E-4 | 0.005587592835299256 | 8.800458715596327E-5 | 7.96231979030144E-4 | 0.023607579729139357 | 0.007012429008300566 | 0.21568108344255127 | 5.112647444298819E-6 | 0.0014136609873307117 | 0.005755220620358234 | 0.007068304936653559 | 4.637702053298382E-5 | 259.75975975975973 |
KO4_4 | 0.3885850694444444 | 0.07688433159722222 | 0.10103211805555555 | 0.0066059461805555554 | 0.019734570312499998 | 0.001695896267361111 | 0.10880381944444444 | 0.016598133680555554 | 0.04829557291666666 | 2.192730034722222E-4 | 0.0010130967881944444 | 0.005662239583333333 | 1.0158723958333333E-4 | 6.189605034722222E-4 | 0.022898763020833334 | 0.006800238715277777 | 0.20595008680555554 | 2.0206423611111107E-5 | 0.0014349891493055556 | 0.005578971354166666 | 0.006939019097222222 | 5.3014105902777776E-5 | 220.25316455696202 |
KO4_5 | 0.3692650918635171 | 0.07301377952755905 | 0.10210739282589676 | 0.00604251968503937 | 0.018015660542432196 | 0.001574971566054243 | 0.10882130358705161 | 0.017204396325459316 | 0.04979483814523184 | 2.0561351706036745E-4 | 9.567322834645669E-4 | 0.0050913823272090986 | 7.525174978127734E-5 | 5.734798775153106E-4 | 0.018211482939632546 | 0.0054270778652668415 | 0.1689667541557305 | 2.254755030621172E-5 | 8.979855643044619E-5 | 0.003944422572178478 | 0.006769860017497812 | 1.2924278215223097E-6 | 242.1768707482993 |
KO9_1 | 0.3592473618870268 | 0.12107231533209188 | 0.05279546865301056 | 0.006351334574798263 | 0.017227995034140287 | 9.169739292364991E-4 | 0.05001675977653632 | 0.01476685288640596 | 0.05795592799503414 | 1.8299782743637493E-4 | 9.963656114214774E-4 | 0.005398634388578523 | 2.1594537554314093E-4 | 0.0014727157045313472 | 0.026913780260707638 | 0.013734761018001243 | 0.27112259466170086 | 1.75455617628802E-5 | 0.0024889292364990694 | 0.00603376784605835 | 0.006152855369335817 | 4.882588454376165E-5 | 316.70281995661605 |
KO9_2 | 0.29945711835334476 | 0.12066037735849057 | 0.05813636363636364 | 0.007166495140080046 | 0.013967352773013149 | 7.093367638650658E-4 | 0.0471672384219554 | 0.014113607775871928 | 0.05374871355060034 | 1.6234305317324187E-4 | 9.68939393939394E-4 | 0.005374871355060034 | 9.835648942252716E-5 | 8.409662664379645E-4 | 0.01769685534591195 | 0.008811863922241281 | 0.20987592910234418 | 9.87221269296741E-6 | 0.0015868667810177244 | 0.00391232132647227 | 0.00595989136649514 | 3.4589308176100627E-6 | 331.08108108108104 |
KO9_3 | 0.3677749860413177 | 0.13247040759352316 | 0.07034142936906755 | 0.008569514237855945 | 0.017746035734226687 | 0.0010533361250697933 | 0.05391652707984366 | 0.018567280848687882 | 0.06141485203796761 | 1.8817225013958682E-4 | 0.0012068732551647125 | 0.005605890563930764 | 1.8710106085985484E-4 | 0.0012997096594081518 | 0.01931711334450028 | 0.011247487437185929 | 0.22780625348967057 | 2.6708319374651033E-5 | 0.0028350809603573416 | 0.004213344500279173 | 0.006248604131769961 | 5.070295924064768E-6 | 326.3757115749525 |
KO9_4 | 0.3980131657690006 | 0.14504518252543389 | 0.06429443447037703 | 0.007883722321962897 | 0.015882256134051465 | 9.261460203470975E-4 | 0.05510951526032316 | 0.01668593656493118 | 0.06659066427289048 | 2.0436445242369837E-4 | 0.001021822262118492 | 0.006314631956912029 | 1.2016935966487133E-4 | 0.001071573907839617 | 0.021201855176540992 | 0.011021903052064632 | 0.24033871932974266 | 2.0742609216038303E-5 | 0.0019938928785158587 | 0.0047072710951526035 | 0.006850418910831837 | 1.5423010173548774E-6 | 325.8426966292135 |
KO9_5 | 0.3500991525423728 | 0.12789999999999996 | 0.06250480225988699 | 0.00834601694915254 | 0.01571652542372881 | 7.912457627118643E-4 | 0.05166581920903953 | 0.015969435028248585 | 0.06069830508474575 | 2.0883107344632764E-4 | 0.0010044124293785309 | 0.0054917514124293776 | 1.6113954802259885E-4 | 0.0012681610169491522 | 0.02167796610169491 | 0.011922881355932202 | 0.242793220338983 | 2.8723305084745755E-5 | 0.00181733615819209 | 0.005455621468926553 | 0.006503389830508473 | 1.0224774011299433E-5 | 290.6574394463668 |
KO21_1 | 0.6273279648609076 | 0.14075866276232304 | 0.31522449975597844 | 0.007022327964860906 | 0.03932503660322108 | 0.0031522449975597846 | 0.2197208394338701 | 0.029462567105905314 | 0.09831259150805269 | 2.7246632503660317E-4 | 0.0011891142020497801 | 0.008145900439238652 | 1.0517886774036113E-4 | 0.0010767569546120057 | 0.03557979502196193 | 0.006304489995119569 | 0.21191825280624693 | 1.0236993655441675E-5 | 0.0016541483650561247 | 0.004900024402147388 | 0.006491752074182526 | 2.2409028794533913E-6 | 360.82474226804123 |
KO21_2 | 0.5903950288504215 | 0.12716200621393695 | 0.28384376387039495 | 0.006102640923213491 | 0.03519662671992897 | 0.0026567776298268967 | 0.1913106968486462 | 0.027816688859298708 | 0.09253306702174877 | 2.9235907678650685E-4 | 0.0010729294274300929 | 0.007976009764758098 | 9.111384820239678E-5 | 9.139769196626718E-4 | 0.032925876608965815 | 0.005591722148246781 | 0.20039369729249884 | 1.3255503772747443E-5 | 8.827541056369284E-5 | 0.004229272081668885 | 0.006301331557922768 | 1.8790457168220147E-6 | 316.504854368932 |
KO21_3 | 0.6770795339412361 | 0.1396274062816616 | 0.29059346504559275 | 0.006544022289766971 | 0.03855141843971631 | 0.0032234169199594734 | 0.21219478216818644 | 0.027860688956433635 | 0.09848429584599798 | 2.604650455927052E-4 | 9.718844984802432E-4 | 0.0075806990881458975 | 1.4902228976697063E-4 | 0.001509660587639311 | 0.051185916919959475 | 0.008001849037487336 | 0.25074620060790276 | 3.5959726443769E-4 | 1.1662613981762919E-4 | 0.005118591691995948 | 0.006835587639311044 | 2.546337386018237E-6 | 378.10945273631836 |
KO21_4 | 0.6318413173652695 | 0.12924026946107786 | 0.29900773453093815 | 0.006254590818363273 | 0.039888972055888226 | 0.002722023453093812 | 0.2032742015968064 | 0.02540129740518962 | 0.09573353293413173 | 2.820948103792415E-4 | 0.0011743313373253493 | 0.008647929141716566 | 1.0690244510978044E-4 | 0.0010626422155688624 | 0.03669785429141717 | 0.006126946107784431 | 0.22720758483033932 | 1.5125898203592814E-5 | 0.0014583408183632734 | 0.005041966067864272 | 0.006733258483033932 | 6.12694610778443E-5 | 339.36651583710403 |
KO21_5 | 0.5538976377952756 | 0.14406933508311462 | 0.3860498687664041 | 0.008308464566929134 | 0.0428011811023622 | 0.0031611329833770773 | 0.2221185476815398 | 0.028534120734908134 | 0.07776946631671042 | 3.3289807524059493E-4 | 0.0016644903762029746 | 0.007469225721784777 | 1.594553805774278E-4 | 0.001499440069991251 | 0.035527777777777776 | 0.007693022747156605 | 0.20421478565179352 | 1.4239085739282589E-5 | 0.002109286964129484 | 0.006574037620297462 | 0.006154418197725284 | 1.5833639545056868E-6 | 233.61344537815128 |
area ratio / mg protein - remove outliers | |||||||||||||||||||||||
C0 | C2:0 | C3:0 | C4:0 | C5:1 | C5:0 | C6:0 | C8:0 | C10:0 | C12:1 | C12:0 | C14:2 | C14:1 | C14:0 | C16:1 | C16:0 | C18:1-OH | C18:2 | C18:1 | C18:0 | C7-DC | C8/C10 | ||
Group | Carnitine | Acetylcarnitine | Propionyl carnitine | Malonyl carnitine | Butyrylcarnitine | Tiglylcarnitine | 2-Methylbutyroylcarnitine | Hexanoylcarnitine | Octanoylcarnitine | Decanoylcarnitine | Dodecenoylcarnitine | Lauroylcarnitine | Tetradecadienylcarnitine | Tetradecenoylcarnitine | Myristoylcarnitine | Hexadecenoylcarnitine | Palmitoylcarnitine | Hydroxyoctadecenoylcarnitine | Linoleylcarnitine | Oleoylcarnitine | Stearoylcarnitine | Pimelylcarnitine | |
WT_1 | 0.6834080841638979 | 0.40721207087486144 | 0.4142940199335547 | 0.02057306201550387 | 0.08073421926910297 | 0.002868189368770763 | 0.25105509413067545 | 0.006444573643410851 | 0.0015013732004429674 | 3.0239922480620147E-5 | 0.0010056367663344404 | 0.009560631229235879 | 1.2464230343300106E-4 | 0.0014376356589147284 | 0.06515393133997784 | 0.008179651162790695 | 0.24114036544850495 | 1.6855038759689916E-5 | 0.0016500941306755257 | 0.0042491694352159454 | 0.005276052048726466 | 2.9673366555924687E-6 | 49.648711943793906 |
WT_2 | 0.6800596089651882 | 0.43304244158321403 | 0.487935145445875 | 0.022627992370052454 | 0.09819694802098235 | 0.0034765379113018595 | 0.31715784453981877 | 0.00814241773962804 | 0.0017321697663328563 | 4.5743919885550774E-5 | 0.0013387720553171194 | 0.008843824511206485 | 2.4884692417739623E-4 | 0.002491518836432999 | 0.07502002861230328 | 0.011222508345255124 | 0.22262041010968045 | 1.3174248927038624E-4 | 0.004543896041964711 | 0.005641750119217929 | 3.476537911301859E-6 | 37.866666666666674 | |
WT_3 | 0.6945520520520521 | 0.4641016016016016 | 0.4833058058058058 | 0.024325325325325324 | 0.09442067067067067 | 0.0033287287287287284 | 0.32327077077077077 | 0.008385835835835836 | 0.0017091741741741742 | 3.264714714714715E-5 | 0.0013923048048048046 | 0.00918601101101101 | 1.3827027027027026E-4 | 0.0018083958958958958 | 0.06433408408408409 | 0.009666116116116117 | 0.22340890890890888 | 2.256493993993994E-5 | 1.251473973973974E-4 | 0.004544994994994995 | 0.005729254254254254 | 1.2642767767767768E-6 | 52.35294117647059 |
WT_4 | 0.6936087450312323 | 0.4975099375354912 | 0.5047728563316297 | 0.023604486087450312 | 0.09006019307211811 | 0.0030395315161839864 | 0.2912430437251562 | 0.008098154457694491 | 0.0017213117546848382 | 4.394065871663827E-5 | 0.0012855366269165247 | 0.00976862578080636 | 1.4053747870528108E-4 | 0.0016305252697331061 | 0.06609256104486087 | 0.008969704713231118 | 0.2640070982396366 | 1.1947501419647927E-5 | 0.0019864082907438954 | 0.004720897217490062 | 0.006282424758659852 | 7.335547984099943E-5 | 39.17355371900827 |
WT_5 | 0.6113338338338337 | 0.46410160160160147 | 0.4224924924924924 | 0.022020820820820814 | 0.0905798298298298 | 0.00279101101101101 | 0.29382432432432426 | 0.006785485485485483 | 0.0013666991991991989 | 3.2647147147147136E-5 | 0.0011714564564564562 | 0.008257807807807806 | 1.3090865865865862E-4 | 0.0015907482482482476 | 0.05697247247247245 | 0.00841784284284284 | 0.20964589589589586 | 3.0086586586586575E-5 | 0.0013506956956956953 | 0.004288938938938938 | 0.0055052052052052035 | 1.0050200200200197E-6 | 41.86274509803922 |
KO4_1 | 0.3644546945469454 | 0.07393972939729396 | 0.11458036080360802 | 0.006397621976219761 | 0.021631303813038127 | 0.002073983189831898 | 0.1263792537925379 | 0.02241789667896679 | 0.05296391963919639 | 2.0739831898318982E-4 | 0.0011405596555965557 | 0.0053750512505125045 | 1.022570725707257E-4 | 6.266523165231652E-4 | 0.017331262812628125 | 0.0063189626896268955 | 0.16544669946699464 | 1.7750779007790076E-5 | 0.0015312341123411232 | 0.004903095530955309 | 0.006214083640836407 | 1.7462361623616234E-6 | 255.37294563843236 |
KO4_2 | 0.31455081300813004 | 0.07070894308943089 | 0.09956443089430893 | 0.0061870325203252025 | 0.0190810162601626 | 0.0018249146341463413 | 0.11672174796747965 | 0.0190810162601626 | 0.04679268292682926 | 1.6923353658536582E-4 | 9.956443089430894E-4 | 0.004575284552845528 | 1.25820325203252E-4 | 9.020589430894307E-4 | 0.02456615853658536 | 0.008370691056910568 | 0.18639085365853655 | 2.144664634146341E-5 | 1.4323760162601623E-4 | 0.005875081300813006 | 0.0063430081300813 | 1.2166097560975608E-6 | 276.4976958525346 |
KO4_3 | 0.39113149847094786 | 0.08074071647007423 | 0.08800458715596328 | 0.007040366972477062 | 0.019556574923547395 | 0.001681865443425076 | 0.10700240279598075 | 0.01829936653560506 | 0.048332678025338555 | 1.8606684141546522E-4 | 9.694473569244208E-4 | 0.005587592835299256 | 8.800458715596327E-5 | 7.96231979030144E-4 | 0.023607579729139357 | 0.007012429008300566 | 0.21568108344255127 | 5.112647444298819E-6 | 0.0014136609873307117 | 0.005755220620358234 | 0.007068304936653559 | 4.637702053298382E-5 | 259.75975975975973 |
KO4_4 | 0.3885850694444444 | 0.07688433159722222 | 0.10103211805555555 | 0.0066059461805555554 | 0.019734570312499998 | 0.001695896267361111 | 0.10880381944444444 | 0.016598133680555554 | 0.04829557291666666 | 2.192730034722222E-4 | 0.0010130967881944444 | 0.005662239583333333 | 1.0158723958333333E-4 | 6.189605034722222E-4 | 0.022898763020833334 | 0.006800238715277777 | 0.20595008680555554 | 2.0206423611111107E-5 | 0.0014349891493055556 | 0.005578971354166666 | 0.006939019097222222 | 5.3014105902777776E-5 | 220.25316455696202 |
KO4_5 | 0.3692650918635171 | 0.07301377952755905 | 0.10210739282589676 | 0.00604251968503937 | 0.018015660542432196 | 0.001574971566054243 | 0.10882130358705161 | 0.017204396325459316 | 0.04979483814523184 | 2.0561351706036745E-4 | 9.567322834645669E-4 | 0.0050913823272090986 | 7.525174978127734E-5 | 5.734798775153106E-4 | 0.018211482939632546 | 0.0054270778652668415 | 0.1689667541557305 | 2.254755030621172E-5 | 8.979855643044619E-5 | 0.003944422572178478 | 0.006769860017497812 | 1.2924278215223097E-6 | 242.1768707482993 |
KO9_1 | 0.3592473618870268 | 0.12107231533209188 | 0.05279546865301056 | 0.006351334574798263 | 0.017227995034140287 | 9.169739292364991E-4 | 0.05001675977653632 | 0.01476685288640596 | 0.05795592799503414 | 1.8299782743637493E-4 | 9.963656114214774E-4 | 0.005398634388578523 | 2.1594537554314093E-4 | 0.0014727157045313472 | 0.026913780260707638 | 0.013734761018001243 | 0.27112259466170086 | 1.75455617628802E-5 | 0.0024889292364990694 | 0.00603376784605835 | 0.006152855369335817 | 4.882588454376165E-5 | 316.70281995661605 |
KO9_2 | 0.29945711835334476 | 0.12066037735849057 | 0.05813636363636364 | 0.007166495140080046 | 0.013967352773013149 | 7.093367638650658E-4 | 0.0471672384219554 | 0.014113607775871928 | 0.05374871355060034 | 1.6234305317324187E-4 | 9.68939393939394E-4 | 0.005374871355060034 | 9.835648942252716E-5 | 8.409662664379645E-4 | 0.01769685534591195 | 0.008811863922241281 | 0.20987592910234418 | 9.87221269296741E-6 | 0.0015868667810177244 | 0.00391232132647227 | 0.00595989136649514 | 3.4589308176100627E-6 | 331.08108108108104 |
KO9_3 | 0.3677749860413177 | 0.13247040759352316 | 0.07034142936906755 | 0.008569514237855945 | 0.017746035734226687 | 0.0010533361250697933 | 0.05391652707984366 | 0.018567280848687882 | 0.06141485203796761 | 1.8817225013958682E-4 | 0.0012068732551647125 | 0.005605890563930764 | 1.8710106085985484E-4 | 0.0012997096594081518 | 0.01931711334450028 | 0.011247487437185929 | 0.22780625348967057 | 2.6708319374651033E-5 | 0.0028350809603573416 | 0.004213344500279173 | 0.006248604131769961 | 5.070295924064768E-6 | 326.3757115749525 |
KO9_4 | 0.3980131657690006 | 0.14504518252543389 | 0.06429443447037703 | 0.007883722321962897 | 0.015882256134051465 | 9.261460203470975E-4 | 0.05510951526032316 | 0.01668593656493118 | 0.06659066427289048 | 2.0436445242369837E-4 | 0.001021822262118492 | 0.006314631956912029 | 1.2016935966487133E-4 | 0.001071573907839617 | 0.021201855176540992 | 0.011021903052064632 | 0.24033871932974266 | 2.0742609216038303E-5 | 0.0019938928785158587 | 0.0047072710951526035 | 0.006850418910831837 | 1.5423010173548774E-6 | 325.8426966292135 |
KO9_5 | 0.3500991525423728 | 0.12789999999999996 | 0.06250480225988699 | 0.00834601694915254 | 0.01571652542372881 | 7.912457627118643E-4 | 0.05166581920903953 | 0.015969435028248585 | 0.06069830508474575 | 2.0883107344632764E-4 | 0.0010044124293785309 | 0.0054917514124293776 | 1.6113954802259885E-4 | 0.0012681610169491522 | 0.02167796610169491 | 0.011922881355932202 | 0.242793220338983 | 2.8723305084745755E-5 | 0.00181733615819209 | 0.005455621468926553 | 0.006503389830508473 | 1.0224774011299433E-5 | 290.6574394463668 |
KO21_1 | 0.6273279648609076 | 0.14075866276232304 | 0.31522449975597844 | 0.007022327964860906 | 0.03932503660322108 | 0.0031522449975597846 | 0.2197208394338701 | 0.029462567105905314 | 0.09831259150805269 | 2.7246632503660317E-4 | 0.0011891142020497801 | 0.008145900439238652 | 1.0517886774036113E-4 | 0.0010767569546120057 | 0.03557979502196193 | 0.006304489995119569 | 0.21191825280624693 | 1.0236993655441675E-5 | 0.0016541483650561247 | 0.004900024402147388 | 0.006491752074182526 | 2.2409028794533913E-6 | 360.82474226804123 |
KO21_2 | 0.5903950288504215 | 0.12716200621393695 | 0.28384376387039495 | 0.006102640923213491 | 0.03519662671992897 | 0.0026567776298268967 | 0.1913106968486462 | 0.027816688859298708 | 0.09253306702174877 | 2.9235907678650685E-4 | 0.0010729294274300929 | 0.007976009764758098 | 9.111384820239678E-5 | 9.139769196626718E-4 | 0.032925876608965815 | 0.005591722148246781 | 0.20039369729249884 | 1.3255503772747443E-5 | 8.827541056369284E-5 | 0.004229272081668885 | 0.006301331557922768 | 1.8790457168220147E-6 | 316.504854368932 |
KO21_3 | 0.6770795339412361 | 0.1396274062816616 | 0.29059346504559275 | 0.006544022289766971 | 0.03855141843971631 | 0.0032234169199594734 | 0.21219478216818644 | 0.027860688956433635 | 0.09848429584599798 | 2.604650455927052E-4 | 9.718844984802432E-4 | 0.0075806990881458975 | 1.4902228976697063E-4 | 0.001509660587639311 | 0.051185916919959475 | 0.008001849037487336 | 0.25074620060790276 | 1.1662613981762919E-4 | 0.005118591691995948 | 0.006835587639311044 | 2.546337386018237E-6 | 378.10945273631836 | |
KO21_4 | 0.6318413173652695 | 0.12924026946107786 | 0.29900773453093815 | 0.006254590818363273 | 0.039888972055888226 | 0.002722023453093812 | 0.2032742015968064 | 0.02540129740518962 | 0.09573353293413173 | 2.820948103792415E-4 | 0.0011743313373253493 | 0.008647929141716566 | 1.0690244510978044E-4 | 0.0010626422155688624 | 0.03669785429141717 | 0.006126946107784431 | 0.22720758483033932 | 1.5125898203592814E-5 | 0.0014583408183632734 | 0.005041966067864272 | 0.006733258483033932 | 6.12694610778443E-5 | 339.36651583710403 |
KO21_5 | 0.5538976377952756 | 0.14406933508311462 | 0.3860498687664041 | 0.008308464566929134 | 0.0428011811023622 | 0.0031611329833770773 | 0.2221185476815398 | 0.028534120734908134 | 0.07776946631671042 | 3.3289807524059493E-4 | 0.0016644903762029746 | 0.007469225721784777 | 1.594553805774278E-4 | 0.001499440069991251 | 0.035527777777777776 | 0.007693022747156605 | 0.20421478565179352 | 1.4239085739282589E-5 | 0.002109286964129484 | 0.006574037620297462 | 0.006154418197725284 | 1.5833639545056868E-6 | 233.61344537815128 |
Mean per clone | |||||||||||||||||||||||
C0 | C2:0 | C3:0 | Malonyl carnitine | C4:0 | C5:1 | C5:0 | C6:0 | C8:0 | C10:0 | C12:1 | C12:0 | C14:2 | C14:1 | C14:0 | C16:1 | C16:0 | C18:1-OH | C18:2 | C18:1 | C18:0 | C7-DC | C8/C10 | |
WT | 0.6725924648092408 | 0.45319353063935397 | 0.4625600640018715 | 0.022630337323830553 | 0.09079837217254079 | 0.003100799707199269 | 0.295310215498149 | 0.00757129343241094 | 0.001606145618966807 | 3.7043759075420695E-5 | 0.001238741341965869 | 0.009123380068013508 | 1.5664112704892147E-4 | 0.0017917647818449952 | 0.0655146155107397 | 0.00929116463604718 | 0.2321645357205253 | 2.0363516676466088E-5 | 0.00104881760075658 | 0.004469579325720931 | 0.005686937277212741 | 1.6413730240938112E-5 | 44.180923720795725 |
KO4 | 0.36559743346679696 | 0.07505750001631609 | 0.1010577779470665 | 0.006454697466923389 | 0.019603825170336063 | 0.001770326220163734 | 0.11354570551749887 | 0.01872016189614986 | 0.04923593833065254 | 1.9751704350332212E-4 | 0.0010150960786246153 | 0.005258310109839944 | 9.858419485891032E-5 | 7.034767239260546E-4 | 0.021323049407763743 | 0.00678587986707653 | 0.18848709550587367 | 1.7412809342175024E-5 | 9.225840814067706E-4 | 0.005211358275694339 | 0.0066668551644582606 | 2.0729280035148618E-5 | 250.8120873111976 |
KO9 | 0.3549183569186125 | 0.12942965656190789 | 0.06161449967774115 | 0.007663416644769938 | 0.01610803301983208 | 8.79407720246064E-4 | 0.05157517194953961 | 0.01602062262082911 | 0.06008169258824766 | 1.8934173132384593E-4 | 0.0010396825904045212 | 0.005637155935382146 | 1.5654236670259865E-4 | 0.0011906253110332465 | 0.021361514045871152 | 0.011347779357085057 | 0.23838734338448825 | 2.071840162625654E-5 | 0.002144421202916417 | 0.00486446524737779 | 0.0063430319217882445 | 1.3824437262818158E-5 | 318.13194973764604 |
KO21 | 0.6161082965626219 | 0.1361715359604228 | 0.3149438663938617 | 0.0068464093126267556 | 0.039152646984223355 | 0.002983119196763409 | 0.2097238135458098 | 0.02781507261234708 | 0.09256659072532832 | 2.8805666660713036E-4 | 0.001214549968297688 | 0.007963952831128798 | 1.2233456627938735E-4 | 0.0012124953494948203 | 0.03838344412401643 | 0.0067436060071589445 | 0.21889610423775627 | 1.321437034276613E-5 | 0.001085335539586041 | 0.005172778372794791 | 0.006503269590435111 | 1.3903822202928726E-5 | 325.68380211770943 |
Replicates vs. mean WT | |||||||||||||||||||||||
C0 | C2:0 | C3:0 | Malonyl carnitine | C4:0 | C5:1 | C5:0 | C6:0 | C8:0 | C10:0 | C12:1 | C12:0 | C14:2 | C14:1 | C14:0 | C16:1 | C16:0 | C18:1-OH | C18:2 | C18:1 | C18:0 | C7-DC | C8/C10 | |
WT_1 | 1.0160804943863362 | 0.8985390199643339 | 0.8956545369465326 | 0.9090921501130123 | 0.8891593245271702 | 0.9249837589030843 | 0.8501402286648938 | 0.851185296269609 | 0.9347677960910935 | 0.8163297471795988 | 0.8118214289502164 | 1.0479264437042768 | 0.7957188880163849 | 0.8023573593373026 | 0.9944945999003423 | 0.8803687678782361 | 1.0386615022838137 | 0.8277076610823864 | 1.5732898928137802 | 0.9506866587563173 | 0.9277492948387754 | 0.1807838079482701 | 1.1450860382347887 |
WT_2 | 1.011102033618627 | 0.9555353558827036 | 1.0548579166659335 | 0.999896380078452 | 1.0814835736744521 | 1.1211746128684874 | 1.0739819616629778 | 1.075432858641068 | 1.0784637120556462 | 1.2348617156378932 | 1.0807518970768366 | 0.9693583348799485 | 1.588643601240672 | 1.3905390158787814 | 1.1450884360300546 | 1.2078688501240047 | 0.9588906825014227 | 0.12561048668076494 | 1.0166272283872695 | 0.9920542190300086 | 0.2118066923404707 | 0.873347759022996 | |
WT_3 | 1.0326491722577347 | 1.024069343944206 | 1.0448498333912595 | 1.0748989278082872 | 1.0398938704677056 | 1.0735065283321157 | 1.0946819778159589 | 1.107582992350822 | 1.064146459692517 | 0.88131301903454 | 1.1239673349363088 | 1.0068648836868133 | 0.8827200932171939 | 1.009281973961881 | 0.9819806402364967 | 1.0403557029453798 | 0.9622869755518721 | 1.108106242082342 | 0.11932236578325962 | 1.0168731023163797 | 1.0074410838345405 | 0.07702556080905337 | 1.2074557356003515 |
WT_4 | 1.0312466780726603 | 1.0977869362645507 | 1.0912590506939817 | 1.0430461441948524 | 0.9918701284752116 | 0.9802411646024626 | 0.9862274599402799 | 1.0695866604546302 | 1.0717034211332062 | 1.1861824991134287 | 1.037776477917813 | 1.0707244144146837 | 0.8971939959381742 | 0.9100107816909654 | 1.0088216275042694 | 0.9654015470171646 | 1.1371551534358488 | 0.5867111073921497 | 1.8939501866778081 | 1.0562285337062667 | 1.1047114558187934 | 4.4691534930945025 | 0.9034894899682081 |
WT_5 | 0.9089216216646417 | 1.0240693439442057 | 0.9133786623022929 | 0.9730663978053965 | 0.9975931028554598 | 0.9000939352938507 | 0.994968371915891 | 0.8962121922838711 | 0.8509186110275369 | 0.8813130190345395 | 0.9456828611188253 | 0.9051259233142779 | 0.8357234215875745 | 0.8878108691310702 | 0.8696146963288376 | 0.9060051320352145 | 0.9030056862270432 | 1.477474989443122 | 1.2878270680443875 | 0.9595844768337665 | 0.9680439464778822 | 0.06123044580770317 | 0.9655123578676971 |
KO4_1 | 0.541865562901171 | 0.16315265862904454 | 0.24770915113662825 | 0.28270113187764273 | 0.23823448918151263 | 0.6688542910451895 | 0.4279542229155633 | 2.9609071262515076 | 32.97578937659883 | 5.598738469304076 | 0.9207407688408138 | 0.5891513025262849 | 0.6528111390490009 | 0.3497402800148221 | 0.2645404033514787 | 0.6801044795946298 | 0.7126269262164822 | 0.8716951639450603 | 1.4599622577238835 | 1.0969926191352366 | 1.0926942461166071 | 0.1063887450767449 | 5.889860645821116 |
KO4_2 | 0.4676692491601764 | 0.15602372564691402 | 0.2152464915213824 | 0.27339550585532085 | 0.21014711831951843 | 0.5885303168435397 | 0.3952513047020253 | 2.5201792045836213 | 29.133524615862548 | 4.568476332026892 | 0.8037548075718638 | 0.501490074811904 | 0.8032394018970277 | 0.5034471891788012 | 0.3749721851387233 | 0.9009302261671883 | 0.802839473652039 | 1.05318971581412 | 0.13657055480637403 | 1.3144595660275864 | 1.1153645311857756 | 0.07412146649414085 | 6.377076841051927 |
KO4_3 | 0.5815282194424817 | 0.1781594639185764 | 0.1902554803252691 | 0.31110305037580255 | 0.21538464242932415 | 0.5423973175436684 | 0.3623389817906636 | 2.4169406058507446 | 30.09233873602927 | 5.022893088053919 | 0.7826067671124292 | 0.6124476667248916 | 0.561822995109567 | 0.44438421108503834 | 0.36034065902850954 | 0.754741658660773 | 0.9290009896351419 | 0.2510689840820792 | 1.3478616170351705 | 1.2876425723644433 | 1.2429018630073319 | 2.8255015680294977 | 5.991037079327587 |
KO4_4 | 0.5777422284304865 | 0.16965010839575698 | 0.21841945710027136 | 0.2919066598976083 | 0.21734497921393484 | 0.5469222224910789 | 0.36843906419189354 | 2.192245463569384 | 30.069236778003965 | 5.919296770767371 | 0.8178436884867916 | 0.6206295847725446 | 0.6485349122367209 | 0.3454474101421245 | 0.34952144406738644 | 0.7319038012624068 | 0.8870867644207031 | 0.9922855630561821 | 1.3681970518709878 | 1.2482094952564229 | 1.220168037552745 | 3.229863359795768 | 5.079866400093642 |
KO4_5 | 0.5490175867019967 | 0.16110949206303332 | 0.22074407362907067 | 0.26700970465324797 | 0.1984139154851554 | 0.5079243146203734 | 0.36849827021217185 | 2.272319317570141 | 31.002692132774115 | 5.550557561983397 | 0.7723422566540349 | 0.5580587774765013 | 0.4804086334093794 | 0.32006426475510563 | 0.27797588061319184 | 0.5841116886693906 | 0.7277888228335143 | 1.10725228183547 | 0.08561884961281035 | 0.8825042100672983 | 1.1904228387790183 | 0.07874065203647712 | 5.585509525226117 |
KO9_1 | 0.5341233818147453 | 0.26715367088600345 | 0.1141375418280748 | 0.2806557623915787 | 0.18973902969760917 | 0.2957217543292198 | 0.16937023222229108 | 1.9503738718133032 | 36.08385647642318 | 4.94004474718112 | 0.8043370941670971 | 0.5917362149041766 | 1.378599475192092 | 0.821935847525075 | 0.4108057423659261 | 1.4782604286995544 | 1.1678036605387156 | 0.861617472150939 | 2.373081110293767 | 1.3499632529925218 | 1.08192777050487 | 2.9746976358843247 | 7.304358224085579 |
KO9_2 | 0.44522817905531564 | 0.26624470386473953 | 0.12568392336638992 | 0.3166764612268272 | 0.1538282288417187 | 0.22875929787343763 | 0.1597209847359684 | 1.864094675746533 | 33.4644087783121 | 4.382467039662826 | 0.7821967033099079 | 0.5891315844556654 | 0.6279097404081425 | 0.46935081823185215 | 0.27012072356604055 | 0.948413279434707 | 0.9039965059736269 | 0.4847990084333826 | 1.5130054833872113 | 0.8753220474146577 | 1.047996676590071 | 0.21073398714589636 | 7.635975005732559 |
KO9_3 | 0.5468021205762768 | 0.2923042776154312 | 0.15206982799272303 | 0.37867372965898927 | 0.1954444260355742 | 0.3396982148263928 | 0.18257589561842166 | 2.4523261467064117 | 38.23741217030759 | 5.0797288082041065 | 0.9742738167190075 | 0.6144532533052051 | 1.194456809554366 | 0.7253796215761256 | 0.29485196843342015 | 1.2105573281468667 | 0.9812276142119262 | 1.3115769637921906 | 2.7031210749249577 | 0.9426713776020906 | 1.098764383565085 | 0.3089057666744607 | 7.5274514868887445 |
KO9_4 | 0.5917597751885076 | 0.3200513085895286 | 0.1389969421789878 | 0.3483696336095289 | 0.17491785099264776 | 0.2986797303278963 | 0.18661567520568412 | 2.2038422779260647 | 41.45991713735556 | 5.51683893655648 | 0.8248875108155115 | 0.6921373339526953 | 0.767163528051867 | 0.5980550118504999 | 0.3236202336113139 | 1.1862778762204536 | 1.0352085799144501 | 1.0186162609138296 | 1.901086401560705 | 1.0531798972811237 | 1.2045884413533283 | 0.09396407731303914 | 7.515158157441905 |
KO9_5 | 0.5205219666587658 | 0.28221938609662384 | 0.1351279695854463 | 0.3687977262435186 | 0.17309259018282044 | 0.25517474117234745 | 0.17495439201751342 | 2.1092083104172348 | 37.79128390848611 | 5.637415820061615 | 0.8108330571937958 | 0.6019426321702206 | 1.028718006939981 | 0.7077720411734604 | 0.33088748110169824 | 1.2832493904665816 | 1.0457808277455962 | 1.4105277364955824 | 1.7327475786839655 | 1.2206118453992483 | 1.1435663017714675 | 0.6229402982265075 | 6.703653786545244 |
KO21_1 | 0.9327014465421181 | 0.3105928334055084 | 0.6814779836996543 | 0.3103059342145176 | 0.4331028812773556 | 1.016590974980123 | 0.7440339951099568 | 3.891351902936814 | 61.21026035690008 | 7.355255833563345 | 0.959937447605219 | 0.8928599245577972 | 0.6714639362082229 | 0.6009477167551313 | 0.5430817954831682 | 0.6785467960238128 | 0.9127933865891972 | 0.5027124645554206 | 1.5771554213648593 | 1.096305501045566 | 1.141519900385509 | 0.13652611847270826 | 8.321975705805736 |
KO21_2 | 0.8777901325699032 | 0.28059095643872056 | 0.6136365543853923 | 0.26966637023068996 | 0.3876349969473695 | 0.8568040120935686 | 0.647829593452873 | 3.673967877169039 | 57.61187897849072 | 7.892262666736033 | 0.8661448448369097 | 0.8742384626419236 | 0.5816725780703844 | 0.5100987188293444 | 0.5025729961518027 | 0.6018322102002613 | 0.863153783029672 | 0.6509437433302813 | 0.08416659913031024 | 0.9462349302832243 | 1.1080360571536234 | 0.1144801144675459 | 7.299792393037142 |
KO21_3 | 1.006671304492339 | 0.30809664490284927 | 0.6282286078298731 | 0.28917033785775176 | 0.4245827047037636 | 1.0395437384993034 | 0.718548736318661 | 3.6797793144786235 | 61.317164946320645 | 7.031280088567717 | 0.7845742008883574 | 0.8309090525258027 | 0.9513611946907701 | 0.8425551182476089 | 0.7812900452963607 | 0.8612320791779267 | 1.0800366207082792 | 0.11119773326982614 | 1.1452065885798624 | 1.2019804872300746 | 0.15513459455226816 | 8.720626141179798 | |
KO21_4 | 0.9394118287430873 | 0.28517677487308557 | 0.6464192605475954 | 0.27638080373538954 | 0.43931373549394354 | 0.8778456237511778 | 0.6883412456758731 | 3.3549482174938032 | 59.60451642965891 | 7.615177763274497 | 0.9480036691612296 | 0.947886537363069 | 0.6824672876389171 | 0.5930701542613483 | 0.5601475946294969 | 0.6594379012522881 | 0.9786489746386026 | 0.7427940096944877 | 1.3904618089086966 | 1.1280627773735767 | 1.1839867673613609 | 3.7328175971254725 | 7.827068294730023 |
KO21_5 | 0.823526380052995 | 0.3178980398944911 | 0.8345940318030616 | 0.3671383438982159 | 0.47138709734827294 | 1.0194573277460424 | 0.7521532816155898 | 3.768724721823648 | 48.41993490399554 | 8.986617005115978 | 1.3436948617226632 | 0.8186906241001423 | 1.0179662492317705 | 0.8368509556523737 | 0.5422878162500055 | 0.8279933731138267 | 0.8796123189875257 | 0.6992449273625982 | 2.011109427042337 | 1.4708403501121636 | 1.0822025807081985 | 0.09646582046027284 | 5.388004727077011 |
Mean Clone vs. mean WT (for WT, this should be 1 everywhere) | |||||||||||||||||||||||
C0 | C2:0 | C3:0 | Malonyl carnitine | C4:0 | C5:1 | C5:0 | C6:0 | C8:0 | C10:0 | C12:1 | C12:0 | C14:2 | C14:1 | C14:0 | C16:1 | C16:0 | C18:1-OH | C18:2 | C18:1 | C18:0 | C7-DC | C8/C10 | |
WT | 1 | 0.9999999999999998 | 1 | 1.0000000000000002 | 0.9999999999999998 | 1.0000000000000002 | 1.0000000000000004 | 1 | 1 | 1 | 1 | 1 | 0.9999999999999998 | 1.0000000000000002 | 1.0000000000000002 | 1 | 1.0000000000000002 | 1 | 1 | 1 | 1 | 0.9999999999999998 | 1.018978276138808 |
KO4 | 0.5435645693272625 | 0.16561908973066503 | 0.21847493074252436 | 0.28522321053192445 | 0.2159050289258891 | 0.57092569250877 | 0.3844963687624635 | 2.4725183435650795 | 30.65471632785375 | 5.331992444427131 | 0.8194576577331866 | 0.5763554812624253 | 0.6293634163403392 | 0.3926166710351783 | 0.32547011443985796 | 0.7303583708708777 | 0.8118685953515762 | 0.8550983417465823 | 0.8796420662098452 | 1.1659616925701974 | 1.1723103033282958 | 1.2629231582865257 | 5.784670098304078 |
KO9 | 0.5276870846587223 | 0.2855946694104653 | 0.13320324099032438 | 0.33863466262608855 | 0.17740442515007407 | 0.2836067477058588 | 0.17464743595997573 | 2.1159690565219096 | 37.407375694176906 | 5.11129907033323 | 0.839305636441064 | 0.6178802037575926 | 0.9993695120292898 | 0.6644986680714027 | 0.32605722981567975 | 1.2213516605936328 | 1.026803437676863 | 1.0174274883571848 | 2.0446083297701216 | 1.0883496841379285 | 1.1153687147569644 | 0.8422483530488456 | 7.337319332138806 |
KO21 | 0.9160202184800884 | 0.30047104990293094 | 0.6808712876531153 | 0.3025323579873129 | 0.431204283154141 | 0.9620483354140429 | 0.7101813704345907 | 3.673754406780385 | 57.63275112307317 | 7.776118671451513 | 0.9804710048428757 | 0.872916920237747 | 0.7809862491680131 | 0.6767045327491613 | 0.5858760495621669 | 0.7258084719536231 | 0.9428490167906552 | 0.6489237862356969 | 1.0348181979432058 | 1.1573300294788786 | 1.1435451585677534 | 0.8470848490156534 | 7.511493452365943 |
A
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* The data in this sheet are relative means of each clone (WT, KO4, KO9, KO21) to the mean of the WT values in each biological replicate (N0, N1, N2, N3). | |||||||||||
MCAD-KO (average for of biological replicate) vs WT | |||||||||||
KO4 | KO9 | KO21 | |||||||||
Acylcarnitine chain length | N=1 | N=2 | N=3 | N=1 | N=2 | N=3 | N=1 | N=2 | N=3 | ||
Carnitine | 0.492168578260898 | 0.6114230570390972 | 0.5435645693272625 | 0.4768809680188087 | 0.5863130882538901 | 0.5276870846587222 | 0.7421345045188547 | 0.911610771895785 | 0.9391436780868617 | ||
C2:0 | 0.09593672876244382 | 0.12093005103650564 | 0.1656190897306651 | 0.21063594864085958 | 0.21686880765082903 | 0.28559466941046535 | 0.33250943050449067 | 0.2666267206225157 | 0.29611430240504094 | ||
C4:0 | 0.18119452775749686 | 0.16942625154156257 | 0.2159050289258891 | 0.28624702193241963 | 0.16746158081542342 | 0.17740442515007407 | 0.45072513096765066 | 0.3608805294796673 | 0.42115857960560804 | ||
C6:0 | 1.18923525647055 | 2.278198703097553 | 2.4725183435650795 | 1.51390032968526 | 1.82993106216639 | 2.1159690565219096 | 3.158417137754578 | 3.2035603601177742 | 3.6500118280195695 | ||
C8:0 | 9.770968713714359 | 26.438259643424146 | 30.654716327853745 | 15.595874550980762 | 28.707435631200244 | 37.407375694176906 | 19.88671869726734 | 40.8113465742166 | 59.935955177842594 | ||
C10:0 | 0.9974719568686857 | 4.6381355653204706 | 5.331992444427131 | 0.815123634586489 | 4.330937392369894 | 5.11129907033323 | 1.1891911629282852 | 5.784068305331566 | 7.473494088035398 | ||
C12:0 | 0.13077854579311352 | 0.5280579793761957 | 0.5763554812624253 | 0.10963749727075468 | 0.5726044700864233 | 0.6178802037575927 | 0.1842899774138038 | 0.7429504587367112 | 0.886473494272148 | ||
C14:0 | 0.09488226925808407 | 0.28435982541878035 | 0.32547011443985796 | 0.08155042245642961 | 0.22784560977851637 | 0.32605722981567975 | 0.15869978941586077 | 0.4506169880303016 | 0.5967731078902071 | ||
C16:0 | 0.32831687558106537 | 0.7504663618484676 | 0.811868595351576 | 0.3084364932747655 | 0.8228605421484357 | 1.026803437676863 | 0.42279970730732186 | 0.8330179719073593 | 0.9586581912414378 | ||
MCAD KO (average of each clone) vs WT | |||||||||||
Acylcarnitine chain length | KO4 | KO9 | KO21 | ||||||||
Carnitine | 0.5490520682090859 | 0.530293713643807 | 0.8642963181671671 | ||||||||
C2:0 | 0.12749528984320488 | 0.23769980856738462 | 0.2984168178440158 | ||||||||
C4:0 | 0.1888419360749828 | 0.21037100929930572 | 0.4109214133509753 | ||||||||
C6:0 | 1.9799841010443942 | 1.8199334827911866 | 3.3373297752973072 | ||||||||
C8:0 | 22.287981561664083 | 27.236895292119303 | 40.21134014977551 | ||||||||
C10:0 | 3.6558666555387624 | 3.419120032429871 | 4.815584518765083 | ||||||||
C12:0 | 0.4117306688105782 | 0.43337405703825693 | 0.6045713101408877 | ||||||||
C14:0 | 0.23490406970557412 | 0.21181775401687522 | 0.40202996177878986 | ||||||||
C16:0 | 0.630217277593703 | 0.7193668243666881 | 0.738158623485373 | ||||||||
C8:0/C10:0 | 6.096497400389873 | 7.9660541407675645 | 8.35025114668476 | ||||||||