Projects

This work aims to identify the biochemical pathways of THP-1 human monocytes infected by different Leishmania infantum clinical isolates from patients with either resistance or with TF outcome, using whole cell differential Mass Spectrometry proteomics. Network enrichment analysis was adopted to integrate the transcriptomics and the proteomic results of infected cells studies. Transferrin Receptor C and Nucleoside Diphosphate Kinase 3 were discovered as overexpressed proteins in THP-1 cells ...