Selected Cell
Cell:
Value:
Sheet1
A
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D
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J
2001
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2200
| "KEGG" | "HIF-1 signaling pathway" | "KEGG:04066" | "1.4278581903841323e-15" | "14.845314922946297" | "109" | "464" | "35" | "7987" | "CDKN1A |
| "KEGG" | "Renal cell carcinoma" | "KEGG:05211" | "1.4740114393487196e-15" | "14.831499146038198" | "68" | "464" | "28" | "7987" | "CDKN1A |
| "KEGG" | "MAPK signaling pathway" | "KEGG:04010" | "4.635175833340166e-15" | "14.333933786438374" | "294" | "464" | "58" | "7987" | "CRK |
| "KEGG" | "Insulin resistance" | "KEGG:04931" | "8.435478079937372e-15" | "14.073890298777883" | "108" | "464" | "34" | "7987" | "PTEN |
| "KEGG" | "Autophagy - animal" | "KEGG:04140" | "1.0886819952135563e-14" | "13.963098959447796" | "136" | "464" | "38" | "7987" | "BCL2 |
| "KEGG" | "T cell receptor signaling pathway" | "KEGG:04660" | "1.3510139059802898e-14" | "13.86934018076374" | "103" | "464" | "33" | "7987" | "PIK3R2 |
| "KEGG" | "Neurotrophin signaling pathway" | "KEGG:04722" | "3.200107695151679e-14" | "13.494835405860382" | "119" | "464" | "35" | "7987" | "BCL2 |
| "KEGG" | "PD-L1 expression and PD-1 checkpoint pathway in cancer" | "KEGG:05235" | "7.098775698219176e-14" | "13.148816546119777" | "89" | "464" | "30" | "7987" | "PTEN |
| "KEGG" | "Bladder cancer" | "KEGG:05219" | "7.488743230539098e-14" | "13.125591059982563" | "41" | "464" | "21" | "7987" | "E2F3 |
| "KEGG" | "Acute myeloid leukemia" | "KEGG:05221" | "1.2490124954452352e-13" | "12.903433216809395" | "67" | "464" | "26" | "7987" | "CCND1 |
| "KEGG" | "Human immunodeficiency virus 1 infection" | "KEGG:05170" | "1.7129527690154e-13" | "12.766254611604701" | "210" | "464" | "46" | "7987" | "WEE1 |
| "KEGG" | "JAK-STAT signaling pathway" | "KEGG:04630" | "1.785373485439637e-13" | "12.748270919216443" | "162" | "464" | "40" | "7987" | "CCND1 |
| "KEGG" | "Viral carcinogenesis" | "KEGG:05203" | "2.2137275983365095e-13" | "12.654875820592638" | "203" | "464" | "45" | "7987" | "CDK6 |
| "KEGG" | "Shigellosis" | "KEGG:05131" | "2.341669418623286e-13" | "12.630474415754415" | "246" | "464" | "50" | "7987" | "BCL2 |
| "KEGG" | "Endometrial cancer" | "KEGG:05213" | "2.844841240554957e-13" | "12.545941964866367" | "58" | "464" | "24" | "7987" | "CCND1 |
| "KEGG" | "Relaxin signaling pathway" | "KEGG:04926" | "3.89290615544204e-13" | "12.409726065499644" | "128" | "464" | "35" | "7987" | "VEGFA |
| "KEGG" | "Central carbon metabolism in cancer" | "KEGG:05230" | "4.3834452245191053e-13" | "12.358184416014566" | "70" | "464" | "26" | "7987" | "PTEN |
| "KEGG" | "Chagas disease" | "KEGG:05142" | "4.55489738884935e-13" | "12.34152140221644" | "101" | "464" | "31" | "7987" | "PIK3R2 |
| "KEGG" | "Yersinia infection" | "KEGG:05135" | "4.726813185017766e-13" | "12.325431561716375" | "136" | "464" | "36" | "7987" | "CRK |
| "KEGG" | "C-type lectin receptor signaling pathway" | "KEGG:04625" | "1.1328099681401957e-12" | "11.945842938071296" | "104" | "464" | "31" | "7987" | "EGR2 |
| "KEGG" | "Growth hormone synthesis | secretion and action" | "KEGG:04935" | "1.2032080920595554e-12" | "11.919659255937113" | "118" | "464" | "33" | "7987" |
| "KEGG" | "p53 signaling pathway" | "KEGG:04115" | "1.4276375829515351e-12" | "11.845382027644353" | "73" | "464" | "26" | "7987" | "CDK6 |
| "KEGG" | "Ras signaling pathway" | "KEGG:04014" | "1.6630167203612544e-12" | "11.779103384259662" | "231" | "464" | "47" | "7987" | "VEGFA |
| "KEGG" | "Signaling pathways regulating pluripotency of stem cells" | "KEGG:04550" | "2.592036243164393e-12" | "11.586358930233443" | "143" | "464" | "36" | "7987" | "PIK3R2 |
| "KEGG" | "Thyroid hormone signaling pathway" | "KEGG:04919" | "2.6825679482897144e-12" | "11.571449268730682" | "121" | "464" | "33" | "7987" | "CCND1 |
| "KEGG" | "Apoptosis" | "KEGG:04210" | "2.9368158928645474e-12" | "11.532123278270925" | "136" | "464" | "35" | "7987" | "BCL2 |
| "KEGG" | "Longevity regulating pathway" | "KEGG:04211" | "3.6362760834841836e-12" | "11.439343150482562" | "88" | "464" | "28" | "7987" | "PIK3R2 |
| "KEGG" | "Toxoplasmosis" | "KEGG:05145" | "6.2975213922785356e-12" | "11.200830348556686" | "110" | "464" | "31" | "7987" | "BCL2 |
| "KEGG" | "AMPK signaling pathway" | "KEGG:04152" | "1.0375048571705725e-11" | "10.984009861423157" | "119" | "464" | "32" | "7987" | "CCND1 |
| "KEGG" | "mTOR signaling pathway" | "KEGG:04150" | "2.995219772992572e-11" | "10.523571305930364" | "154" | "464" | "36" | "7987" | "PTEN |
| "KEGG" | "Chemokine signaling pathway" | "KEGG:04062" | "5.344220451220243e-11" | "10.272115635342805" | "190" | "464" | "40" | "7987" | "CRK |
| "KEGG" | "Non-alcoholic fatty liver disease" | "KEGG:04932" | "6.909274664156908e-11" | "10.160567542479413" | "150" | "464" | "35" | "7987" | "ITCH |
| "KEGG" | "IL-17 signaling pathway" | "KEGG:04657" | "1.6893224391299059e-10" | "9.772287449203418" | "94" | "464" | "27" | "7987" | "IL13 |
| "KEGG" | "Osteoclast differentiation" | "KEGG:04380" | "2.7141213331619884e-10" | "9.566370741368665" | "125" | "464" | "31" | "7987" | "PIK3R2 |
| "KEGG" | "Transcriptional misregulation in cancer" | "KEGG:05202" | "2.949628824401681e-10" | "9.530232631362942" | "191" | "464" | "39" | "7987" | "CDKN1A |
| "KEGG" | "Rap1 signaling pathway" | "KEGG:04015" | "3.685013332813075e-10" | "9.433560936473404" | "210" | "464" | "41" | "7987" | "CRK |
| "KEGG" | "Th1 and Th2 cell differentiation" | "KEGG:04658" | "3.8265056720681655e-10" | "9.417197638574937" | "90" | "464" | "26" | "7987" | "NOTCH1 |
| "KEGG" | "Th17 cell differentiation" | "KEGG:04659" | "4.809789403247113e-10" | "9.317873938804956" | "105" | "464" | "28" | "7987" | "TGFBR2 |
| "KEGG" | "Influenza A" | "KEGG:05164" | "5.772552874824402e-10" | "9.23863208038752" | "169" | "464" | "36" | "7987" | "CDK6 |
| "KEGG" | "TGF-beta signaling pathway" | "KEGG:04350" | "8.800441359394531e-10" | "9.055495546583588" | "93" | "464" | "26" | "7987" | "TGFBR2 |
| "KEGG" | "Longevity regulating pathway - multiple species" | "KEGG:04213" | "1.138345002578631e-9" | "8.943726094699594" | "61" | "464" | "21" | "7987" | "PIK3R2 |
| "KEGG" | "Insulin signaling pathway" | "KEGG:04910" | "2.913201567747269e-9" | "8.535629465000959" | "136" | "464" | "31" | "7987" | "CRK |
| "KEGG" | "Platinum drug resistance" | "KEGG:01524" | "3.957014771190203e-9" | "8.402632328547613" | "71" | "464" | "22" | "7987" | "CDKN1A |
| "KEGG" | "Hippo signaling pathway" | "KEGG:04390" | "6.7535390072699174e-9" | "8.170468587383123" | "157" | "464" | "33" | "7987" | "CCND1 |
| "KEGG" | "Adipocytokine signaling pathway" | "KEGG:04920" | "1.197996991011351e-8" | "7.921544272755395" | "68" | "464" | "21" | "7987" | "IRS1 |
| "KEGG" | "Sphingolipid signaling pathway" | "KEGG:04071" | "1.2407417042649729e-8" | "7.906318619861439" | "119" | "464" | "28" | "7987" | "BCL2 |
| "KEGG" | "Choline metabolism in cancer" | "KEGG:05231" | "1.985574671742833e-8" | "7.702113775728747" | "98" | "464" | "25" | "7987" | "PIK3R2 |
| "KEGG" | "Toll-like receptor signaling pathway" | "KEGG:04620" | "5.0124602857411674e-8" | "7.2999490553197495" | "102" | "464" | "25" | "7987" | "PIK3R2 |
| "KEGG" | "Leishmaniasis" | "KEGG:05140" | "5.271849047887302e-8" | "7.278037033658383" | "73" | "464" | "21" | "7987" | "TGFB1 |
| "KEGG" | "Salmonella infection" | "KEGG:05132" | "9.623956910625416e-8" | "7.016646330132001" | "249" | "464" | "41" | "7987" | "BCL2 |
| "KEGG" | "Inflammatory bowel disease" | "KEGG:05321" | "1.4848349237679615e-7" | "6.828321826267089" | "63" | "464" | "19" | "7987" | "TGFB1 |
| "KEGG" | "Wnt signaling pathway" | "KEGG:04310" | "2.2054162542425525e-7" | "6.656509428935619" | "160" | "464" | "31" | "7987" | "CCND1 |
| "KEGG" | "Cushing syndrome" | "KEGG:04934" | "2.5575936811223916e-7" | "6.592168449717706" | "152" | "464" | "30" | "7987" | "E2F3 |
| "KEGG" | "VEGF signaling pathway" | "KEGG:04370" | "3.306442214060645e-7" | "6.480639062959664" | "59" | "464" | "18" | "7987" | "VEGFA |
| "KEGG" | "Estrogen signaling pathway" | "KEGG:04915" | "3.912741557003206e-7" | "6.407518837014766" | "137" | "464" | "28" | "7987" | "BCL2 |
| "KEGG" | "Parathyroid hormone synthesis | secretion and action" | "KEGG:04928" | "6.279961783989408e-7" | "6.202042999105641" | "106" | "464" | "24" | "7987" |
| "KEGG" | "Platelet activation" | "KEGG:04611" | "8.166737238661326e-7" | "6.087951417429159" | "124" | "464" | "26" | "7987" | "PIK3R2 |
| "KEGG" | "Amoebiasis" | "KEGG:05146" | "0.0000011684322753124637" | "5.932396455124961" | "101" | "464" | "23" | "7987" | "PIK3R2 |
| "KEGG" | "Pathogenic Escherichia coli infection" | "KEGG:05130" | "0.0000026236568754655436" | "5.58109296306002" | "196" | "464" | "33" | "7987" | "CDC42 |
| "KEGG" | "Leukocyte transendothelial migration" | "KEGG:04670" | "0.000002881733166693607" | "5.540346235040948" | "114" | "464" | "24" | "7987" | "PIK3R2 |
| "KEGG" | "Regulation of actin cytoskeleton" | "KEGG:04810" | "0.000003031441670582117" | "5.518350783816293" | "217" | "464" | "35" | "7987" | "CRK |
| "KEGG" | "Progesterone-mediated oocyte maturation" | "KEGG:04914" | "0.000003246199830535031" | "5.488624749257955" | "98" | "464" | "22" | "7987" | "PIK3R2 |
| "KEGG" | "Adherens junction" | "KEGG:04520" | "0.000008267720065878328" | "5.08261423643547" | "71" | "464" | "18" | "7987" | "TGFBR2 |
| "KEGG" | "Tuberculosis" | "KEGG:05152" | "0.00000875583525330305" | "5.057702418558481" | "176" | "464" | "30" | "7987" | "BCL2 |
| "KEGG" | "B cell receptor signaling pathway" | "KEGG:04662" | "0.000008964991167039339" | "5.047450134000066" | "79" | "464" | "19" | "7987" | "PIK3R2 |
| "KEGG" | "Type II diabetes mellitus" | "KEGG:04930" | "0.00001485165809507686" | "4.828225057367414" | "45" | "464" | "14" | "7987" | "PIK3R2 |
| "KEGG" | "Fc epsilon RI signaling pathway" | "KEGG:04664" | "0.000018901291303501605" | "4.723508524566008" | "67" | "464" | "17" | "7987" | "PIK3R2 |
| "KEGG" | "Phospholipase D signaling pathway" | "KEGG:04072" | "0.000031088437598634925" | "4.507401103603052" | "147" | "464" | "26" | "7987" | "PIK3R2 |
| "KEGG" | "Bacterial invasion of epithelial cells" | "KEGG:05100" | "0.00003141201390297066" | "4.502904219000751" | "77" | "464" | "18" | "7987" | "CRK |
| "KEGG" | "NF-kappa B signaling pathway" | "KEGG:04064" | "0.00003250094669269282" | "4.488103988638831" | "102" | "464" | "21" | "7987" | "BCL2 |
| "KEGG" | "Fc gamma R-mediated phagocytosis" | "KEGG:04666" | "0.00005113460897058995" | "4.2912850607785815" | "96" | "464" | "20" | "7987" | "CRK |
| "KEGG" | "Alzheimer disease" | "KEGG:05010" | "0.00005879937289906396" | "4.2306273056913515" | "368" | "464" | "46" | "7987" | "APP |
| "KEGG" | "Thyroid cancer" | "KEGG:05216" | "0.00007184399429216894" | "4.143609530310332" | "37" | "464" | "12" | "7987" | "CCND1 |
| "KEGG" | "cAMP signaling pathway" | "KEGG:04024" | "0.00008914609877633676" | "4.049897657726784" | "216" | "464" | "32" | "7987" | "PIK3R2 |
| "KEGG" | "Apelin signaling pathway" | "KEGG:04371" | "0.00009396488115200708" | "4.027034431205613" | "136" | "464" | "24" | "7987" | "CCND1 |
| "KEGG" | "Mitophagy - animal" | "KEGG:04137" | "0.00013229234897208414" | "3.8784652721790045" | "68" | "464" | "16" | "7987" | "E2F1 |
| "KEGG" | "NOD-like receptor signaling pathway" | "KEGG:04621" | "0.000165138523142813" | "3.7821516036797633" | "180" | "464" | "28" | "7987" | "BCL2 |
| "KEGG" | "Axon guidance" | "KEGG:04360" | "0.00018498200256498266" | "3.732870523310142" | "181" | "464" | "28" | "7987" | "RGS3 |
| "KEGG" | "Apoptosis - multiple species" | "KEGG:04215" | "0.0009223962592614575" | "3.0350824669724656" | "32" | "464" | "10" | "7987" | "BCL2 |
| "KEGG" | "Rheumatoid arthritis" | "KEGG:05323" | "0.0012919079277475855" | "2.8887684367248454" | "89" | "464" | "17" | "7987" | "VEGFA |
| "KEGG" | "GnRH secretion" | "KEGG:04929" | "0.0015341267769961083" | "2.8141387497254873" | "64" | "464" | "14" | "7987" | "PIK3R2 |
| "KEGG" | "Malaria" | "KEGG:05144" | "0.0018872626812765528" | "2.7241676477474828" | "49" | "464" | "12" | "7987" | "VCAM1 |
| "KEGG" | "GnRH signaling pathway" | "KEGG:04912" | "0.002368738874705763" | "2.6254828124409895" | "93" | "464" | "17" | "7987" | "RAF1 |
| "KEGG" | "Cholinergic synapse" | "KEGG:04725" | "0.002702860776988852" | "2.5681763240174043" | "113" | "464" | "19" | "7987" | "BCL2 |
| "KEGG" | "Natural killer cell mediated cytotoxicity" | "KEGG:04650" | "0.0027512002779691053" | "2.5604777933068474" | "123" | "464" | "20" | "7987" | "PIK3R2 |
| "KEGG" | "Pertussis" | "KEGG:05133" | "0.0028186065758642213" | "2.5499655391887766" | "76" | "464" | "15" | "7987" | "CASP7 |
| "KEGG" | "Aldosterone-regulated sodium reabsorption" | "KEGG:04960" | "0.003828263720481574" | "2.416998152294127" | "37" | "464" | "10" | "7987" | "PIK3R2 |
| "KEGG" | "Tight junction" | "KEGG:04530" | "0.004036378621963984" | "2.3940081026637396" | "168" | "464" | "24" | "7987" | "CCND1 |
| "KEGG" | "Notch signaling pathway" | "KEGG:04330" | "0.0044114600018579" | "2.3554176541117706" | "53" | "464" | "12" | "7987" | "ATXN1 |
| "KEGG" | "Epithelial cell signaling in Helicobacter pylori infection" | "KEGG:05120" | "0.0044917147727775815" | "2.3475878295569963" | "70" | "464" | "14" | "7987" | "CDC42 |
| "KEGG" | "Basal cell carcinoma" | "KEGG:05217" | "0.00600053911780699" | "2.22180972872129" | "63" | "464" | "13" | "7987" | "CDKN1A |
| "KEGG" | "Autophagy - other" | "KEGG:04136" | "0.006746898924371756" | "2.170895795983198" | "32" | "464" | "9" | "7987" | "MTOR |
| "KEGG" | "Oxytocin signaling pathway" | "KEGG:04921" | "0.00851527118444842" | "2.0698015165758203" | "154" | "464" | "22" | "7987" | "CCND1 |
| "KEGG" | "Necroptosis" | "KEGG:04217" | "0.013808577922798906" | "1.8598510449609766" | "159" | "464" | "22" | "7987" | "BCL2 |
| "KEGG" | "Gap junction" | "KEGG:04540" | "0.016534517702546853" | "1.781608468556591" | "88" | "464" | "15" | "7987" | "RAF1 |
| "KEGG" | "RIG-I-like receptor signaling pathway" | "KEGG:04622" | "0.018737677313362795" | "1.727284244425149" | "70" | "464" | "13" | "7987" | "CHUK |
| "KEGG" | "Regulation of lipolysis in adipocytes" | "KEGG:04923" | "0.030158373892453676" | "1.520592078869009" | "55" | "464" | "11" | "7987" | "PIK3R2 |
| "KEGG" | "Coronavirus disease - COVID-19" | "KEGG:05171" | "0.043499686926726754" | "1.3615138687116681" | "231" | "464" | "27" | "7987" | "PIK3R2 |
| "KEGG" | "Glucagon signaling pathway" | "KEGG:04922" | "0.04780239211835488" | "1.3205503699609493" | "107" | "464" | "16" | "7987" | "SIRT1 |
| "REAC" | "Signal Transduction" | "REAC:R-HSA-162582" | "6.91470261038225e-32" | "31.160226493421234" | "2687" | "549" | "270" | "10531" | "E2F3 |
| "REAC" | "Cytokine Signaling in Immune system" | "REAC:R-HSA-1280215" | "1.5884835059055601e-31" | "30.79901729033094" | "816" | "549" | "132" | "10531" | "CCND1 |
| "REAC" | "Signaling by Interleukins" | "REAC:R-HSA-449147" | "8.371589217954744e-30" | "29.07719209002666" | "446" | "549" | "93" | "10531" | "CCND1 |
| "REAC" | "Interleukin-4 and Interleukin-13 signaling" | "REAC:R-HSA-6785807" | "7.924948787557664e-28" | "27.10100353559008" | "110" | "549" | "46" | "10531" | "CCND1 |
| "REAC" | "Signaling by Receptor Tyrosine Kinases" | "REAC:R-HSA-9006934" | "1.9532737972677103e-27" | "26.709236875857965" | "486" | "549" | "94" | "10531" | "SPRED1 |
| "REAC" | "Generic Transcription Pathway" | "REAC:R-HSA-212436" | "6.630113841722668e-21" | "20.17847901452019" | "1179" | "549" | "143" | "10531" | "TP53INP1 |
| "REAC" | "Diseases of signal transduction by growth factor receptors and second messengers" | "REAC:R-HSA-5663202" | "1.1848748946862702e-20" | "19.926327502325325" | "359" | "549" | "71" | "10531" | "SPRED1 |
| "REAC" | "Extracellular matrix organization" | "REAC:R-HSA-1474244" | "1.0814683844831719e-19" | "18.965986172152025" | "298" | "549" | "63" | "10531" | "APP |
| "REAC" | "Gene expression (Transcription)" | "REAC:R-HSA-74160" | "2.2181685322610343e-17" | "16.654005460057732" | "1434" | "549" | "154" | "10531" | "TP53INP1 |
| "REAC" | "Immune System" | "REAC:R-HSA-168256" | "2.3630536312152548e-17" | "16.62652642162767" | "2116" | "549" | "200" | "10531" | "CCND1 |
| "REAC" | "ESR-mediated signaling" | "REAC:R-HSA-8939211" | "2.748674890902247e-17" | "16.56087662481164" | "181" | "549" | "46" | "10531" | "CCND1 |
| "REAC" | "RNA Polymerase II Transcription" | "REAC:R-HSA-73857" | "3.2509306982879094e-17" | "16.487992288477404" | "1300" | "549" | "144" | "10531" | "TP53INP1 |
| "REAC" | "Signaling by Nuclear Receptors" | "REAC:R-HSA-9006931" | "6.521158124857003e-16" | "15.185675268904602" | "255" | "549" | "53" | "10531" | "CCND1 |
| "REAC" | "Cellular Senescence" | "REAC:R-HSA-2559583" | "6.107326374895904e-14" | "13.21414887073135" | "158" | "549" | "39" | "10531" | "E2F3 |
| "REAC" | "PIP3 activates AKT signaling" | "REAC:R-HSA-1257604" | "1.4600367260056521e-13" | "12.83563621976283" | "249" | "549" | "49" | "10531" | "CDKN1A |
| "REAC" | "Intracellular signaling by second messengers" | "REAC:R-HSA-9006925" | "1.991292290046407e-13" | "12.70086498776896" | "289" | "549" | "53" | "10531" | "CDKN1A |
| "REAC" | "Signaling by PDGF" | "REAC:R-HSA-186797" | "2.3413906136552357e-13" | "12.630526127010926" | "54" | "549" | "23" | "10531" | "CRK |
| "REAC" | "Signaling by VEGF" | "REAC:R-HSA-194138" | "2.3314396651732206e-12" | "11.632375819077765" | "104" | "549" | "30" | "10531" | "CRK |
| "REAC" | "PI3K/AKT Signaling in Cancer" | "REAC:R-HSA-2219528" | "1.4069752559337412e-11" | "10.851713540309342" | "89" | "549" | "27" | "10531" | "CDKN1A |
| "REAC" | "FOXO-mediated transcription" | "REAC:R-HSA-9614085" | "4.1661655776708275e-11" | "10.380263473697013" | "66" | "549" | "23" | "10531" | "CDKN1A |
| "REAC" | "Extra-nuclear estrogen signaling" | "REAC:R-HSA-9009391" | "5.275749203826243e-11" | "10.277715857929158" | "73" | "549" | "24" | "10531" | "CCND1 |
| "REAC" | "Mitotic G1 phase and G1/S transition" | "REAC:R-HSA-453279" | "5.674909387277731e-11" | "10.246041068569985" | "148" | "549" | "34" | "10531" | "WEE1 |
| "REAC" | "Degradation of the extracellular matrix" | "REAC:R-HSA-1474228" | "6.017847537486883e-11" | "10.220558819332213" | "140" | "549" | "33" | "10531" | "CD44 |
| "REAC" | "VEGFA-VEGFR2 Pathway" | "REAC:R-HSA-4420097" | "6.253826529573695e-11" | "10.203854169510382" | "94" | "549" | "27" | "10531" | "CRK |
| "REAC" | "Disease" | "REAC:R-HSA-1643685" | "1.4027446366723645e-10" | "9.853021383125698" | "1397" | "549" | "134" | "10531" | "CDK6 |
| "REAC" | "Transcriptional Regulation by TP53" | "REAC:R-HSA-3700989" | "1.6954374041531136e-10" | "9.770718239818496" | "360" | "549" | "55" | "10531" | "TP53INP1 |
| "REAC" | "Cyclin D associated events in G1" | "REAC:R-HSA-69231" | "5.477963133594305e-10" | "9.261380894851396" | "43" | "549" | "18" | "10531" | "E2F3 |
| "REAC" | "G1 Phase" | "REAC:R-HSA-69236" | "5.477963133594305e-10" | "9.261380894851396" | "43" | "549" | "18" | "10531" | "E2F3 |
| "REAC" | "Non-integrin membrane-ECM interactions" | "REAC:R-HSA-3000171" | "2.2326078191805076e-9" | "8.651187558578519" | "58" | "549" | "20" | "10531" | "FGF2 |
| "REAC" | "Signaling by TGFB family members" | "REAC:R-HSA-9006936" | "2.2727851710923947e-9" | "8.643441612853298" | "100" | "549" | "26" | "10531" | "TGFBR2 |
| "REAC" | "Intrinsic Pathway for Apoptosis" | "REAC:R-HSA-109606" | "2.342900237447434e-9" | "8.630246203613238" | "52" | "549" | "19" | "10531" | "BCL2 |
| "REAC" | "Downstream signal transduction" | "REAC:R-HSA-186763" | "2.493586671396822e-9" | "8.603175532095623" | "26" | "549" | "14" | "10531" | "CRK |
| "REAC" | "Negative regulation of the PI3K/AKT network" | "REAC:R-HSA-199418" | "5.6726439499119685e-9" | "8.246214474577584" | "96" | "549" | "25" | "10531" | "PTEN |
| "REAC" | "SUMO E3 ligases SUMOylate target proteins" | "REAC:R-HSA-3108232" | "7.873083028117539e-9" | "8.103855168542339" | "156" | "549" | "32" | "10531" | "ESR1 |
| "REAC" | "Signaling by TGF-beta Receptor Complex" | "REAC:R-HSA-170834" | "1.8447866798098912e-8" | "7.734053845839677" | "71" | "549" | "21" | "10531" | "TGFBR2 |
| "REAC" | "Transcriptional regulation by RUNX2" | "REAC:R-HSA-8878166" | "2.2328051906607702e-8" | "7.651149166902482" | "118" | "549" | "27" | "10531" | "CCND1 |
| "REAC" | "SUMOylation" | "REAC:R-HSA-2990846" | "2.2472276765228434e-8" | "7.648352925067099" | "162" | "549" | "32" | "10531" | "ESR1 |
| "REAC" | "Developmental Biology" | "REAC:R-HSA-1266738" | "2.6567587203252442e-8" | "7.5756478852545355" | "1069" | "549" | "105" | "10531" | "CDKN1A |
| "REAC" | "Estrogen-dependent gene expression" | "REAC:R-HSA-9018519" | "3.6390985908348196e-8" | "7.439006178303428" | "112" | "549" | "26" | "10531" | "CCND1 |
| "REAC" | "MAPK family signaling cascades" | "REAC:R-HSA-5683057" | "3.8753656866639543e-8" | "7.411687310394586" | "276" | "549" | "43" | "10531" | "SPRED1 |
| "REAC" | "TP53 Regulates Transcription of Cell Cycle Genes" | "REAC:R-HSA-6791312" | "8.23125273908992e-8" | "7.084534063175211" | "49" | "549" | "17" | "10531" | "CCNE1 |
| "REAC" | "Integrin cell surface interactions" | "REAC:R-HSA-216083" | "8.789398224860911e-8" | "7.056040858324267" | "84" | "549" | "22" | "10531" | "VCAM1 |
| "REAC" | "SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription" | "REAC:R-HSA-2173796" | "9.096839340154626e-8" | "7.0411094753233545" | "32" | "549" | "14" | "10531" | "RBL1 |
| "REAC" | "G0 and Early G1" | "REAC:R-HSA-1538133" | "9.245186615101053e-8" | "7.0340843181348065" | "27" | "549" | "13" | "10531" | "CCNE1 |
| "REAC" | "Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer" | "REAC:R-HSA-2173793" | "1.269343041216068e-7" | "6.896420993528407" | "44" | "549" | "16" | "10531" | "RBL1 |
| "REAC" | "Oncogene Induced Senescence" | "REAC:R-HSA-2559585" | "1.5051582347142518e-7" | "6.822417841033004" | "33" | "549" | "14" | "10531" | "E2F3 |
| "REAC" | "G1/S Transition" | "REAC:R-HSA-69206" | "2.7969291809070154e-7" | "6.553318529956922" | "131" | "549" | "27" | "10531" | "WEE1 |
| "REAC" | "Deactivation of the beta-catenin transactivating complex" | "REAC:R-HSA-3769402" | "6.235203564709185e-7" | "6.205149363262143" | "42" | "549" | "15" | "10531" | "SOX2 |
| "REAC" | "Apoptosis" | "REAC:R-HSA-109581" | "6.715772636976506e-7" | "6.172904015359769" | "174" | "549" | "31" | "10531" | "BCL2 |
| "REAC" | "Platelet activation | signaling and aggregation" | "REAC:R-HSA-76002" | "7.493752150491013e-7" | "6.125300674927051" | "258" | "549" | "39" | "10531" |
| "REAC" | "Syndecan interactions" | "REAC:R-HSA-3000170" | "8.746422484923592e-7" | "6.058169548436454" | "26" | "549" | "12" | "10531" | "FGF2 |
| "REAC" | "MyD88:MAL(TIRAP) cascade initiated on plasma membrane" | "REAC:R-HSA-166058" | "9.070967810311792e-7" | "6.042346374212806" | "94" | "549" | "22" | "10531" | "APP |
| "REAC" | "Transcriptional regulation by RUNX3" | "REAC:R-HSA-8878159" | "9.070967810311792e-7" | "6.042346374212806" | "94" | "549" | "22" | "10531" | "CCND1 |
| "REAC" | "Toll Like Receptor TLR6:TLR2 Cascade" | "REAC:R-HSA-168188" | "9.070967810311792e-7" | "6.042346374212806" | "94" | "549" | "22" | "10531" | "APP |
| "REAC" | "Programmed Cell Death" | "REAC:R-HSA-5357801" | "0.0000010362286805623632" | "5.984544391553245" | "177" | "549" | "31" | "10531" | "BCL2 |
| "REAC" | "Signaling by NTRKs" | "REAC:R-HSA-166520" | "0.0000011570789064709908" | "5.936637023523234" | "130" | "549" | "26" | "10531" | "CRK |
| "REAC" | "Collagen degradation" | "REAC:R-HSA-1442490" | "0.000001160848402279788" | "5.935224492020373" | "64" | "549" | "18" | "10531" | "ADAM9 |
| "REAC" | "Oxidative Stress Induced Senescence" | "REAC:R-HSA-2559580" | "0.0000011651792061147942" | "5.933607274430727" | "87" | "549" | "21" | "10531" | "E2F3 |
| "REAC" | "Signaling by SCF-KIT" | "REAC:R-HSA-1433557" | "0.0000013948084172756081" | "5.85548544044338" | "38" | "549" | "14" | "10531" | "PIK3R2 |
| "REAC" | "Toll Like Receptor 2 (TLR2) Cascade" | "REAC:R-HSA-181438" | "0.000001709469459938179" | "5.76713865356806" | "97" | "549" | "22" | "10531" | "APP |
| "REAC" | "Toll Like Receptor TLR1:TLR2 Cascade" | "REAC:R-HSA-168179" | "0.000001709469459938179" | "5.76713865356806" | "97" | "549" | "22" | "10531" | "APP |
| "REAC" | "Toll-like Receptor Cascades" | "REAC:R-HSA-168898" | "0.0000019676043937394134" | "5.706062216314652" | "152" | "549" | "28" | "10531" | "APP |
| "REAC" | "Hemostasis" | "REAC:R-HSA-109582" | "0.000002625143724418633" | "5.58084691434823" | "657" | "549" | "70" | "10531" | "WEE1 |
| "REAC" | "Signaling by ERBB2" | "REAC:R-HSA-1227986" | "0.000002662403913350583" | "5.574726057038515" | "46" | "549" | "15" | "10531" | "CUL5 |
| "REAC" | "Assembly of collagen fibrils and other multimeric structures" | "REAC:R-HSA-2022090" | "0.000002866493138535344" | "5.542649093449677" | "60" | "549" | "17" | "10531" | "MMP7 |
| "REAC" | "Toll Like Receptor 3 (TLR3) Cascade" | "REAC:R-HSA-168164" | "0.00000344403370984592" | "5.462932606368087" | "92" | "549" | "21" | "10531" | "APP |
| "REAC" | "MyD88 cascade initiated on plasma membrane" | "REAC:R-HSA-975871" | "0.000003627471579575991" | "5.44039598147649" | "84" | "549" | "20" | "10531" | "APP |
| "REAC" | "Toll Like Receptor 5 (TLR5) Cascade" | "REAC:R-HSA-168176" | "0.000003627471579575991" | "5.44039598147649" | "84" | "549" | "20" | "10531" | "APP |
| "REAC" | "Toll Like Receptor 10 (TLR10) Cascade" | "REAC:R-HSA-168142" | "0.000003627471579575991" | "5.44039598147649" | "84" | "549" | "20" | "10531" | "APP |
| "REAC" | "Signaling by NOTCH" | "REAC:R-HSA-157118" | "0.000003900377929984268" | "5.408893309651817" | "197" | "549" | "32" | "10531" | "E2F3 |
| "REAC" | "p130Cas linkage to MAPK signaling for integrins" | "REAC:R-HSA-372708" | "0.00000498584500288478" | "5.3022612267223685" | "15" | "549" | "9" | "10531" | "CRK |
| "REAC" | "TRIF(TICAM1)-mediated TLR4 signaling " | "REAC:R-HSA-937061" | "0.000007736794546384702" | "5.111438935849669" | "96" | "549" | "21" | "10531" | "APP |
| "REAC" | "MyD88-independent TLR4 cascade " | "REAC:R-HSA-166166" | "0.000007736794546384702" | "5.111438935849669" | "96" | "549" | "21" | "10531" | "APP |
| "REAC" | "CD28 co-stimulation" | "REAC:R-HSA-389356" | "0.000010048711089830518" | "4.997889639982031" | "31" | "549" | "12" | "10531" | "PIK3R2 |
| "REAC" | "FLT3 Signaling" | "REAC:R-HSA-9607240" | "0.00001201619344129747" | "4.920233088844247" | "250" | "549" | "36" | "10531" | "SPRED1 |
| "REAC" | "Elastic fibre formation" | "REAC:R-HSA-1566948" | "0.00001239962681430905" | "4.906591385396248" | "44" | "549" | "14" | "10531" | "ITGB8 |
| "REAC" | "TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation" | "REAC:R-HSA-975138" | "0.000012839698652956455" | "4.891445169015914" | "90" | "549" | "20" | "10531" | "APP |
| "REAC" | "Signaling by Non-Receptor Tyrosine Kinases" | "REAC:R-HSA-9006927" | "0.000013012768735269661" | "4.885630288487012" | "51" | "549" | "15" | "10531" | "CCND1 |
| "REAC" | "Signaling by PTK6" | "REAC:R-HSA-8848021" | "0.000013012768735269661" | "4.885630288487012" | "51" | "549" | "15" | "10531" | "CCND1 |
| "REAC" | "Integrin signaling" | "REAC:R-HSA-354192" | "0.000013093095730270528" | "4.8829576567632555" | "26" | "549" | "11" | "10531" | "CRK |
| "REAC" | "Constitutive Signaling by AKT1 E17K in Cancer" | "REAC:R-HSA-5674400" | "0.000013093095730270528" | "4.8829576567632555" | "26" | "549" | "11" | "10531" | "CDKN1A |
| "REAC" | "Toll Like Receptor 4 (TLR4) Cascade" | "REAC:R-HSA-166016" | "0.000013095924284160147" | "4.882863844520558" | "126" | "549" | "24" | "10531" | "APP |
| "REAC" | "MyD88 dependent cascade initiated on endosome" | "REAC:R-HSA-975155" | "0.000015670187773764915" | "4.8049257994075205" | "91" | "549" | "20" | "10531" | "APP |
| "REAC" | "Toll Like Receptor 7/8 (TLR7/8) Cascade" | "REAC:R-HSA-168181" | "0.000015670187773764915" | "4.8049257994075205" | "91" | "549" | "20" | "10531" | "APP |
| "REAC" | "Cyclin E associated events during G1/S transition " | "REAC:R-HSA-69202" | "0.00001719323146919519" | "4.764642489959474" | "83" | "549" | "19" | "10531" | "WEE1 |
| "REAC" | "ECM proteoglycans" | "REAC:R-HSA-3000178" | "0.00001800505652951706" | "4.744605510759301" | "75" | "549" | "18" | "10531" | "APP |
| "REAC" | "FOXO-mediated transcription of cell cycle genes" | "REAC:R-HSA-9617828" | "0.000022037251978300292" | "4.6568425625003" | "17" | "549" | "9" | "10531" | "CDKN1A |
| "REAC" | "Regulation of RUNX1 Expression and Activity" | "REAC:R-HSA-8934593" | "0.000022037251978300292" | "4.6568425625003" | "17" | "549" | "9" | "10531" | "CDK6 |
| "REAC" | "CD28 dependent PI3K/Akt signaling" | "REAC:R-HSA-389357" | "0.000024791500521336387" | "4.605697186486932" | "22" | "549" | "10" | "10531" | "PIK3R2 |
| "REAC" | "Regulation of TP53 Activity" | "REAC:R-HSA-5633007" | "0.000025898870941290206" | "4.58671916853093" | "160" | "549" | "27" | "10531" | "TP53INP1 |
| "REAC" | "Cyclin A:Cdk2-associated events at S phase entry" | "REAC:R-HSA-69656" | "0.000025949411831479206" | "4.585872481408504" | "85" | "549" | "19" | "10531" | "WEE1 |
| "REAC" | "MET promotes cell motility" | "REAC:R-HSA-8875878" | "0.000029603124114609846" | "4.528662454003888" | "40" | "549" | "13" | "10531" | "CRK |
| "REAC" | "G1/S-Specific Transcription" | "REAC:R-HSA-69205" | "0.000033072949166822984" | "4.48052707663846" | "28" | "549" | "11" | "10531" | "CCNE1 |
| "REAC" | "Toll Like Receptor 9 (TLR9) Cascade" | "REAC:R-HSA-168138" | "0.000033744944412847846" | "4.471791282923787" | "95" | "549" | "20" | "10531" | "APP |
| "REAC" | "TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest" | "REAC:R-HSA-6804114" | "0.00004204553125959414" | "4.37628015569081" | "18" | "549" | "9" | "10531" | "RBL1 |
| "REAC" | "Cell Cycle | Mitotic" | "REAC:R-HSA-69278" | "0.00004239711097780977" | "4.372663736075729" | "512" | "549" | "56" | "10531" |
| "REAC" | "Interleukin-21 signaling" | "REAC:R-HSA-9020958" | "0.000052203687622337306" | "4.2822988177359305" | "10" | "549" | "7" | "10531" | "JAK1 |
| "REAC" | "PI5P | PP2A and IER3 Regulate PI3K/AKT Signaling" | "REAC:R-HSA-6811558" | "0.000056828644578232205" | "4.245432702202926" | "89" | "549" | "19" | "10531" |
| "REAC" | "TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest" | "REAC:R-HSA-6804116" | "0.00005837197109966469" | "4.233795641223775" | "14" | "549" | "8" | "10531" | "CCNE1 |
| "REAC" | "Pre-NOTCH Transcription and Translation" | "REAC:R-HSA-1912408" | "0.00006727811178993617" | "4.172126205835572" | "57" | "549" | "15" | "10531" | "E2F3 |
| "REAC" | "Estrogen-dependent nuclear events downstream of ESR-membrane signaling" | "REAC:R-HSA-9634638" | "0.0000683792000796098" | "4.165075984016807" | "24" | "549" | "10" | "10531" | "CCND1 |
