Selected Cell
Cell:
Value:
Foglio1
A
B
C
D
E
F
G
H
I
J
K
L
M
N
O
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
61
62
63
64
65
66
67
68
69
70
71
72
73
74
75
76
77
78
79
80
81
82
83
84
85
86
87
88
89
90
91
92
93
94
95
96
97
98
99
100
101
102
103
104
105
106
107
108
109
110
111
112
113
114
115
116
117
118
119
120
121
122
123
124
125
126
127
128
129
130
131
132
133
134
135
136
137
138
139
140
141
142
143
144
145
146
147
148
149
150
151
152
153
154
155
156
157
158
159
160
161
162
163
164
165
166
167
168
169
170
171
172
173
174
175
176
177
178
179
180
181
182
183
184
185
186
187
188
189
190
191
192
193
194
195
196
197
198
199
200
| Table S1a. Activity and toxicity profile of the 456-training set of Ty-Box compounds: % antiparasitic activity against T. brucei, L. major and T. cruzi at 50 µM, % antitubercular activity against replicant (ss18b) and non-replicant (h37rv) Mtb at 20 µM, % inhibition against hERG and CYP isoforms at 10 µM, % A549 cell growth and % mitochondrial toxicity at 10 µM. | ||||||||||||||
| Molecule | T. brucei | L. major | T. cruzi | ss18 | h37rv | hERG | CYP1A2 | CYP2C9 | CYP2C19 | CYP2D6 | CYP3A4 | A549 | Mitochondrial toxicity | |
| Ty-101 | 0.41 | 26.6 | -6.53 | 10.15 | -3.35 | 1.95 | 1.7 | -0.92 | -35.5 | -48.76 | -11.88 | 137.56 | -5.75 | |
| Ty-102 | -0.8 | 1.38 | -1.79 | 1.34 | -9.04 | 11.17 | 4.17 | -4.74 | -36.14 | -34.37 | -9.15 | 128.79 | -2.32 | |
| Ty-103 | 102.85 | 87.77 | 89.54 | 87.02 | 62.49 | 9.98 | -0.13 | -1.01 | 20.19 | -9.07 | -14.49 | 132.28 | 5.29 | |
| Ty-104 | 1.41 | 33.2 | 10.81 | -3.95 | -7.8 | 9.6 | 4.94 | -4.3 | -55.22 | -30.92 | -7.48 | 142.38 | 6.28 | |
| Ty-105 | -0.4 | 6.64 | 2.35 | -13.94 | -0.93 | -9 | 6.8 | 6.83 | -22.69 | -9.38 | 9.37 | 120.83 | -8.88 | |
| Ty-106 | -1 | 1.82 | 0.58 | -11.4 | 18.68 | 4.19 | -1.1 | 0.34 | -37.56 | -31.63 | -4.69 | 138 | -5.14 | |
| Ty-107 | -1.81 | 33.66 | 14.2 | -23.68 | -4.99 | 2.45 | 2.58 | 2.55 | -16.85 | -24.23 | -14.07 | 153.66 | -8.2 | |
| Ty-108 | -0.4 | 37.5 | 0.76 | -8.63 | -8.73 | 8.24 | 0.95 | 0.08 | -27.97 | -25.31 | -8.03 | 149.48 | -0.11 | |
| Ty-109 | 102.17 | 93.89 | 81.77 | 83.56 | 64.35 | 3.49 | 1.91 | -1.54 | -38.08 | -18.61 | -19.43 | 136.43 | 0.2 | |
| Ty-110 | 0.61 | -9.29 | 34.27 | -3.84 | 16.49 | 9.12 | 4.16 | -2 | -30.4 | -22.2 | -22.73 | 147 | -9.38 | |
| Ty-111 | -1 | -12.95 | -10.96 | -8.95 | 9.04 | -32.11 | 2.34 | -1.37 | -47.22 | -23.07 | -14.03 | 146.86 | 10.66 | |
| Ty-112 | -1 | -54.2 | -24.77 | -1.26 | 11.68 | 13.67 | -1.49 | -1.09 | -24.87 | -16.73 | -3.33 | 156.01 | -1.08 | |
| Ty-114 | -0.6 | 2.56 | -25.64 | 9.63 | -0.03 | -1.36 | -1.55 | -13.08 | -24.25 | -38.76 | -19.36 | 114.85 | -1.37 | |
| Ty-115 | 0.41 | 26.68 | -10.51 | 15.15 | 2.71 | -0.56 | -5.45 | -9.32 | -35.32 | -39.75 | -0.85 | 127.07 | -2.92 | |
| Ty-116 | -0.8 | 21.5 | -14.85 | 9.02 | -0.2 | 1.66 | 10.17 | -6.51 | -26.22 | -32.78 | -16.52 | 132.55 | -6.87 | |
| Ty-117 | 0.2 | 31.21 | -6.48 | 3.63 | 1.18 | -10.94 | 3.19 | -11.55 | -37.87 | -35.2 | -1.14 | 130.42 | -0.35 | |
| Ty-118 | 0.41 | 33.84 | -4.99 | 0.2 | -8.4 | -9.44 | 9.75 | -3.35 | -28.61 | -46.79 | -14.67 | 133.19 | -5.26 | |
| Ty-119 | 1.42 | -20.34 | -13.73 | 11.03 | 12.58 | -26.38 | 1.69 | -5.03 | -36.36 | -16.97 | -21.44 | 147.28 | 4.09 | |
| Ty-120 | -1.61 | -69.54 | -45.52 | -3.8 | -8.81 | 21.13 | 7.49 | 40.86 | -7.11 | -8.56 | 37.09 | 158.84 | 13.24 | |
| Ty-121 | 0.81 | 6.93 | 19.49 | -9.61 | 6.76 | 27.01 | 17.27 | 6.71 | 24 | -6.77 | 19.98 | 162.12 | 3.59 | |
| Ty-122 | -0.2 | 21.25 | -15.04 | -17.86 | 15.23 | -2.43 | 2.94 | -6.91 | -38.83 | -41.51 | -12.46 | 133.6 | -6.11 | |
| Ty-123 | -2.81 | -48.6 | 1.29 | -9.81 | 16.07 | 4.43 | 9.5 | -2.37 | -16.67 | -14.6 | 7.8 | 113.51 | 1.26 | |
| Ty-124 | -1.4 | 17.7 | -30.26 | -1.61 | 6.91 | -7.44 | 5.2 | -5.05 | -49.48 | -32.53 | -11.08 | 141.72 | 6.67 | |
| Ty-125 | 106.46 | 88.21 | 91.29 | 82.39 | 82.06 | 12.6 | 3.27 | 4.84 | -24.72 | -8.62 | -1 | 57.41 | 5.38 | |
| Ty-126 | -1.4 | -7.63 | -9.66 | -10.3 | 1.44 | 14.52 | 8.4 | 3.21 | -27.5 | -23.05 | 26.62 | 126.99 | -5.28 | |
| Ty-127 | 98.34 | 4.31 | 90.88 | 104.86 | 96.13 | -3.72 | 12.94 | 4.28 | -7.06 | -25.17 | -2.35 | 59.84 | 1.22 | |
| Ty-128 | -1.2 | -110.63 | 0.12 | 0.26 | 6.79 | 0.93 | -6.28 | 1.1 | -3.28 | -20.23 | -8.6 | 107.7 | -2.41 | |
| Ty-129 | 2.42 | -4.22 | -9.28 | 15.64 | 19.66 | -7.24 | 10.19 | 7.67 | 14.26 | -5.86 | 30.74 | 135.52 | -4.43 | |
| Ty-130 | 69.81 | 14.03 | -30.13 | 26.29 | -6.24 | 30.2 | 6.17 | 23.11 | 25.23 | -3.9 | 21.17 | 158.97 | -6.97 | |
| Ty-131 | -0.4 | 0.75 | -0.1 | 10.02 | 20.82 | -3.47 | 9.02 | -1.39 | -35.53 | -17.44 | 3.13 | 140.8 | -4.98 | |
| Ty-132 | 2.32 | 22.49 | 0.12 | 4.48 | -1.98 | 1.22 | 14.47 | 13.17 | 7.89 | -11.37 | 54.41 | 140.46 | -1.18 | |
| Ty-134 | 16.52 | -2.53 | 48.98 | 38.7 | -26.3 | -9.57 | 0.31 | 2.63 | -28.03 | -12.18 | -6.63 | 143.19 | 2.26 | |
| Ty-135 | 1.42 | 11.39 | -22.9 | 7.6 | -13.58 | 5.41 | 2.89 | -4.31 | -18.95 | -22.25 | -11.76 | 151.48 | 1.02 | |
| Ty-136 | -1.2 | -5.29 | -2.56 | 7.6 | -13.58 | -4.07 | 12.1 | -0.82 | -34.65 | -20.83 | -3.44 | 155.28 | -10.47 | |
| Ty-137 | 1.01 | 27.91 | -14.49 | -18.05 | 5.65 | -7.63 | 10.09 | 2.73 | -37.49 | -27.01 | -9.95 | 164.5 | 0.25 | |
| Ty-138 | -0.2 | 14.22 | -5.16 | -15.51 | 2.12 | -8.72 | 2.97 | -2.24 | -31.42 | -23.71 | -14.78 | 141.7 | -5.91 | |
| Ty-139 | 2.42 | 25.75 | -8.21 | -9.51 | -1.79 | -6.05 | 10.13 | -0.32 | -36.01 | -28.16 | -17.34 | 149.16 | -4.71 | |
| Ty-140 | 0.01 | 15.73 | -5.95 | -7.51 | 13.98 | -5.78 | 4.95 | -6.45 | -34.93 | -18.38 | -18.98 | 149.47 | 5.41 | |
| Ty-141 | -0.2 | -35.13 | -16.78 | -4.54 | 4.57 | -3.12 | 3.69 | -0.01 | -26.52 | -14.09 | -13.71 | 155.43 | -1.03 | |
| Ty-142 | -0.4 | -63.03 | -29.54 | -8.75 | 20.97 | -6.07 | -11.22 | -4.22 | -16.42 | -18.38 | -22.68 | 106.05 | 6.51 | |
| Ty-144 | -1.2 | -35.86 | 15.67 | -0.82 | 12.61 | 65.88 | -3.5 | -9.25 | -11.48 | -20.74 | -20.5 | 110.07 | -9.39 | |
| Ty-145 | -0.8 | -22 | 5.03 | 72.68 | 89.17 | 5.17 | -8.35 | -8.84 | -29.94 | -33.1 | -4.76 | 111.65 | -7.34 | |
| Ty-146 | 86.83 | -2.11 | 64.18 | 72.68 | 89.17 | -9.68 | 3 | -2.89 | -29.28 | -17.54 | -5.05 | 47.46 | -8.3 | |
| Ty-147 | -0.2 | 24.95 | -6.12 | 0.36 | -0.76 | 5.54 | -7.35 | -7.13 | -21.05 | -12.91 | -11.85 | 117.89 | -4.21 | |
| Ty-149 | 0.61 | 6.7 | -5.75 | -4.62 | 6.83 | 4.04 | 3.6 | -4.7 | -33.33 | -34.9 | -9.05 | 129.38 | -1.72 | |
| Ty-150 | -1.41 | 24.43 | 9.27 | -4.62 | 6.83 | 2.4 | -0.96 | -0.59 | -57.64 | -38.43 | 1.16 | 118.13 | 6.78 | |
| Ty-151 | 1.62 | 28.85 | -11.34 | 0.36 | -0.76 | 4.03 | 3.72 | -6.6 | -46.84 | -33.79 | -18.06 | 128.26 | -2.69 | |
| Ty-152 | -2.21 | 21.01 | -16.84 | -5.38 | -24.31 | -1.43 | 5.64 | -4.39 | -49.49 | -41.62 | -1.67 | 133.36 | -6.88 | |
| Ty-153 | 41.64 | 6.05 | -47.82 | 2.48 | 2.61 | -5.97 | 11.16 | 1.51 | -36.41 | -19.6 | 6.28 | 142.74 | -1.94 | |
| Ty-154 | -0.8 | 30.76 | -18.74 | -12.39 | -6.4 | 1.87 | 4.83 | 2.12 | -42.07 | -34.21 | -13.76 | 138 | -9.63 | |
| Ty-155 | 0.21 | 20.22 | -23.69 | -16 | 0.69 | 4.76 | 2.33 | 1.04 | -55.62 | -23.23 | -11.82 | 129.86 | -5.42 | |
| Ty-156 | -0.6 | 20.1 | -9.97 | -16.01 | -7.92 | 17.13 | 6.66 | 4.27 | -34.45 | -36.51 | -17 | 143.73 | 6.93 | |
| Ty-157 | -0.2 | 24.58 | 8.26 | -15.95 | 2.33 | 3.27 | -3.71 | -0.51 | -49.54 | -38.17 | -9.47 | 163.23 | -5.37 | |
| Ty-158 | 1.21 | -4.02 | -28.43 | -4.61 | 14.33 | -13.84 | 7 | 0.14 | 2.79 | -16.48 | 48.46 | 156.83 | -10.17 | |
| Ty-159 | 0.41 | 26.52 | 36.59 | -5.21 | 7.35 | 24.26 | 28.07 | 7.81 | 22.21 | -17.59 | 29.53 | 151.12 | 1.81 | |
| Ty-160 | 0.01 | 0.31 | -4.95 | 0.39 | 31.1 | -1.28 | -3.11 | 0.57 | -43.73 | -26.71 | -10.65 | 149.95 | 3.06 | |
| Ty-161 | 0.01 | -0.28 | -10.51 | -1.62 | 0.47 | -11.35 | 27.18 | 19.91 | 65.73 | 22.32 | 95.33 | 154.13 | -3.39 | |
| Ty-162 | 1.01 | -7.48 | -3.53 | -0.49 | 22.66 | 1.49 | 5.89 | 1.52 | -34.57 | -22.55 | -16.43 | 154.41 | 10.69 | |
| Ty-163 | 0.01 | -7.01 | 21.43 | 6.34 | 11.92 | 2.97 | -3.81 | -5.01 | -27.76 | -21.61 | -23.23 | 167.9 | -4.02 | |
| Ty-164 | -1.4 | -51.37 | -29.24 | 18.33 | 8.63 | 2.99 | 1.74 | -1.58 | -20.35 | -11.38 | -13.51 | 157.73 | -0.9 | |
| Ty-165 | 2.02 | -45.21 | 3.68 | 7.67 | -3.11 | 8.35 | -11.42 | -5.69 | -14.64 | -28.1 | -25.42 | 112.05 | -0.01 | |
| Ty-166 | 1.22 | -0.77 | 18.46 | -5.22 | 16.06 | 2.17 | -3.55 | -5.77 | -23.69 | -25.68 | 2.6 | 114.56 | -6.42 | |
| Ty-167 | 1.62 | 19.8 | -1.54 | -1.48 | -6.57 | 3.45 | 2.61 | -3.46 | -28.35 | -11.83 | -13.22 | 119.55 | 0.6 | |
| Ty-168 | -0.8 | -74.13 | 73.41 | 27.58 | -11.93 | 1.99 | 0.77 | -8.62 | -49.03 | -54.69 | -11.65 | 126.65 | -6.98 | |
| Ty-169 | 0.41 | 24.71 | 8.06 | 2.75 | -8.02 | 25.32 | 13.63 | 31.23 | -6.13 | -27.17 | -12.65 | 132.5 | 2.92 | |
| Ty-170 | 0.01 | -2.03 | -28.67 | -9.32 | -1.83 | -14.02 | 59.31 | 51.09 | 76.18 | 2.52 | 75.08 | 115.03 | -6.71 | |
| Ty-171 | -0.4 | 19.37 | -13.22 | 12.31 | -11.46 | -4.04 | 8.91 | 2.61 | -40.32 | -37.03 | -13.64 | 126.45 | -4.63 | |
| Ty-172 | -0.4 | 13.1 | 49.75 | 5.2 | -17.07 | 4.27 | 31.32 | 24.24 | 40.42 | -3.95 | -17.93 | 126.86 | -1.67 | |
| Ty-173 | 105.52 | 20.62 | 66.93 | -10.61 | -3.07 | 18.08 | 1.17 | 24.83 | -7.81 | 102.94 | 6.55 | 122.57 | -11.15 | |
| Ty-174 | 54.49 | -14.54 | 2.46 | -2.09 | 14.34 | -12.33 | -6.81 | -2.96 | -20.54 | -16.51 | 6.76 | 107.23 | -5.64 | |
| Ty-175 | 64.29 | 14.95 | 25.57 | 39.67 | -2.3 | 27.78 | 38.36 | 16.23 | -12.57 | -13.19 | 1.36 | 135.33 | -5.19 | |
| Ty-176 | 69.81 | -13.26 | 3.83 | 5.04 | 8.26 | -2.28 | 33.43 | 3.6 | -23.43 | -12.52 | 5.11 | 84 | -4.61 | |
| Ty-177 | 47.32 | -28.84 | 10.38 | 15.83 | -21.87 | 21.66 | 61.77 | 38.13 | 89.93 | 18.98 | 81.87 | 146.31 | -1.62 | |
| Ty-179 | 121.81 | 12.22 | -0.69 | 23.21 | 15.5 | 21.03 | 14.02 | 50.93 | 33.73 | 47.84 | 41.99 | 151.1 | 5.07 | |
| Ty-180 | 0.41 | 26.25 | 2.4 | 17.13 | 15.21 | 0.32 | 5.12 | 3.4 | -37.6 | -28.71 | -8.16 | 146.22 | -6.31 | |
| Ty-181 | -0.2 | 5.57 | 16.46 | -8.96 | -22.14 | -1.83 | 48.17 | 66.15 | 65.14 | -2.24 | -13.5 | 154.19 | -2.5 | |
| Ty-201 | 48.32 | 20.06 | 23.48 | -8.05 | 2.06 | -8.88 | 13.87 | 58.97 | 10.46 | 96.05 | 14.98 | 157.51 | -6.16 | |
| Ty-203 | -1.2 | -24.35 | -9.26 | 6.83 | 3.39 | -3.01 | 1.55 | -7.5 | -18.77 | -24.29 | -33.97 | 104.1 | -2.22 | |
| Ty-204 | 1.62 | 8.63 | 36.01 | 7.94 | 6.99 | 3.27 | -0.93 | -3.76 | 8.33 | -20.07 | 17.57 | 157.88 | -9.35 | |
| Ty-206 | -0.6 | 36.62 | -51.54 | 3.24 | 4.41 | -5.78 | 9.19 | 0.58 | -18.06 | -25.87 | -0.5 | 147.58 | 8.86 | |
| Ty-209 | 0.21 | 19.92 | -22.76 | 11.29 | 20.46 | 13.34 | 7.41 | 0.94 | -15.66 | -29.25 | 7.81 | 127.14 | -2.79 | |
| Ty-210 | 0.21 | -30.63 | -2.88 | 7.72 | 3.93 | 6.95 | 21.98 | 10.87 | 20.57 | -42.31 | -24.19 | 107.25 | -4.13 | |
| Ty-212 | -0.4 | 35.13 | -30.09 | 6.41 | 18.49 | -4.03 | 43.57 | 3.41 | 42.92 | 38.61 | 20.7 | 154.93 | 6.62 | |
| Ty-215 | -0.8 | -26.17 | -28.79 | 8.4 | 23.81 | -37.09 | 80.15 | -1.64 | 62.17 | 79.46 | 13.72 | 156.35 | 6.8 | |
| Ty-216 | -0.8 | -3.9 | 14.8 | 7.66 | 18.48 | 2.63 | 66.31 | 6.36 | 35.89 | -12.26 | -0.22 | 120.68 | -5.6 | |
| Ty-217 | 1.21 | -2.41 | 51.13 | 14.3 | 22.08 | -4.54 | 37.07 | 1.58 | -14.99 | -27.17 | -4.38 | 120.85 | 8.02 | |
| Ty-218 | 0.81 | 14.3 | 9.51 | -8.52 | -0.73 | -16.21 | 5.37 | 4.35 | -23.94 | -28.56 | -10.76 | 145.17 | 6.43 | |
| Ty-219 | 60.65 | -24.93 | -15.4 | 14.06 | 2.05 | 2.06 | 5.04 | -14.29 | -11.86 | -31.27 | -1.01 | 112.89 | -3.38 | |
| Ty-220 | 39.16 | 34.18 | -7.32 | 29.19 | -23.81 | 1.04 | -1.51 | -10.4 | -30.14 | -29.34 | -3.74 | 119.96 | 1.37 | |
| Ty-221 | 91.38 | 39.54 | 39.22 | 6.8 | -3.97 | -6.86 | 33.81 | 8.26 | 50.29 | -33.75 | -18.03 | 131.94 | 1.65 | |
| Ty-222 | 84.84 | 23.49 | 17.54 | -11.23 | 7.22 | -1.79 | 19.17 | 7.25 | -27.44 | -32.77 | -9.26 | 121.22 | 3.8 | |
| Ty-223 | -0.2 | 14.79 | -3.37 | -9.73 | -5.26 | -9.99 | 18.18 | -1.51 | -34.8 | -22.81 | 1.11 | 126.18 | -9.75 | |
| Ty-224 | 40.73 | -7.78 | 25.98 | -4.03 | 6.03 | -4.76 | 17.42 | -3.78 | -28.31 | -20.07 | -15.22 | 159.85 | 1.22 | |
| Ty-225 | 5.05 | 15.49 | 12 | -8.79 | 19.35 | -5.53 | 26.38 | -0.22 | -32.21 | -44.49 | -18.37 | 143.24 | 1.3 | |
| Ty-226 | 82.08 | -57.49 | 77.28 | -5.14 | 14.78 | 8.48 | 44.37 | 1.94 | 32.14 | -2.18 | -23.03 | 104.8 | -4.83 | |
| Ty-227 | 8.21 | 12.18 | 17.22 | -3.54 | 1.74 | -11.16 | 43.96 | 19.39 | -26.67 | -22.91 | -2.79 | 118.76 | -4.08 | |
| Ty-228 | 0.21 | 9.14 | 44.93 | -3.84 | 5.01 | -13.62 | 24.35 | 0.23 | 5.22 | -29.9 | -8.53 | 142.21 | -2.66 | |
| Ty-229 | 0.41 | 16.22 | -4.05 | 2.5 | -2.62 | -5.03 | 32.41 | 7.58 | -26.34 | -23.9 | -1.8 | 152.87 | -0.8 | |
| Ty-230 | 87.91 | 38.95 | 33.19 | 2.26 | 23.64 | -5.41 | 31.93 | 0.62 | -10.18 | -21.75 | 1.2 | 146.31 | -7.93 | |
| Ty-231 | 83.24 | 15.68 | 21.62 | 3.05 | 10.83 | 0.56 | 10.84 | 0.64 | -22.9 | -25.04 | 1.91 | 111.57 | 3.41 | |
| Ty-232 | 23.4 | 8.03 | -1.56 | 5.78 | 3.87 | -9.03 | 15.05 | 8.79 | -26.3 | -28.86 | -5.12 | 110.26 | -0.96 | |
| Ty-233 | -0.6 | -34.87 | 81.52 | 14.57 | 6.96 | 1.74 | 53.09 | 35.87 | 74.54 | -0.99 | -5.87 | 155.82 | 16.5 | |
| Ty-234 | -1 | 11.24 | 25.01 | 2.97 | -14.28 | -4.81 | 55.28 | 33.11 | 8.24 | -15.31 | -7.43 | 138.79 | 3.77 | |
| Ty-235 | 69.46 | 24.64 | 40.59 | 0.03 | -1.16 | -2.37 | 46.61 | 36.44 | -19.47 | -28.94 | 8.15 | 123.35 | -8.45 | |
| Ty-236 | 63 | 31.68 | 39.22 | 4.1 | -11.62 | -15.13 | 39.1 | 28.44 | -20.28 | -32.74 | 3.32 | 114.79 | -4.15 | |
| Ty-237 | 0.41 | 14.78 | 17.43 | 14.35 | 7.88 | -9.91 | 48.7 | 0.57 | -31.95 | -32.99 | -13.5 | 150.51 | -0.99 | |
| Ty-238 | 43.9 | 33.49 | 19.79 | -17.53 | -4.14 | 0.91 | 5.33 | 4.53 | -31.93 | -18.74 | 4.01 | 117.6 | -0.13 | |
| Ty-239 | 1.62 | 22.93 | 18.38 | -9.44 | 15.73 | 7.04 | 5.69 | -0.47 | -30.19 | -29.72 | -0.51 | 113.41 | -6.57 | |
| Ty-240 | -0.4 | 24.77 | -1.66 | -7.52 | 6.55 | -0.78 | 0.48 | -4.11 | -35.69 | -39.47 | -8.39 | 125.37 | -4.15 | |
| Ty-241 | 0.21 | 30.16 | -10.38 | -7.88 | 0.93 | -7.44 | 0.38 | -15.27 | -34.26 | -38.77 | -0.01 | 122.81 | -4.39 | |
| Ty-242 | -0.2 | 8.55 | -29.52 | -6.28 | -7.39 | -35.87 | -6.08 | -48.86 | -35.1 | -34.71 | -16.92 | 160.96 | -4.35 | |
| Ty-243 | -0.2 | 13.59 | -0.03 | -7.17 | 16.17 | 14.72 | 2.24 | -13.48 | -39.34 | -19.79 | -24.36 | 148.6 | 11.13 | |
| Ty-244 | -0.8 | 44.25 | -0.69 | -1.12 | 12.75 | 7.85 | 4.65 | -44.76 | -35.74 | -36.63 | -10.11 | 155.34 | -5.8 | |
| Ty-245 | 1.21 | 23.71 | -6.21 | -1.44 | 8.96 | -3.73 | 8.14 | -352.75 | -44.8 | -36.14 | -6.41 | 146.6 | -0.23 | |
| Ty-246 | 1.21 | 28.38 | -49.85 | 2.33 | 12.84 | -9.56 | 1.9 | -14.22 | -41.73 | -42.65 | -6.4 | 145.91 | -7.88 | |
| Ty-247 | -0.19 | 19.75 | -0.15 | 22.21 | 21.82 | -4 | 6.78 | -8.6 | -42.84 | -30.85 | -3.42 | 132.84 | -3.53 | |
| Ty-248 | -1.6 | -12.83 | -4.31 | 11.81 | 4.56 | -0.63 | -4.55 | -50.19 | -28.36 | -52.55 | -20.55 | 119.04 | -0.01 | |
| Ty-249 | 0.81 | -6.09 | -12.41 | 18.31 | 9.44 | 3.19 | 4.57 | -452.94 | -40.86 | -36.9 | -2.93 | 131.38 | -6.6 | |
| Ty-250 | 24.67 | 32.84 | 56.29 | 11.11 | -11.47 | 0.53 | 6.36 | -338.08 | -20.74 | -35.49 | 3.62 | 118.85 | -4.28 | |
| Ty-251 | 106.71 | -98.44 | 91.49 | 59.22 | -65.74 | 1.24 | 49.31 | 22 | 25.05 | 6.6 | 0.09 | 145.95 | 12.54 | |
| Ty-252 | 0.61 | -1.72 | -9.76 | -4.08 | -26.34 | -4.21 | -0.15 | -10.79 | -54.25 | -32.68 | -12.25 | 115.57 | 0.23 | |
| Ty-253 | 1.21 | 27.4 | -12.83 | 4.8 | 6.25 | -8.45 | 5.61 | -2.07 | -31.9 | -35.14 | -5.22 | 135.83 | -7.53 | |
| Ty-254 | -0.39 | 31.65 | -8.44 | -11.41 | 12.8 | -2.59 | 10.86 | -68.45 | -37.29 | -30.95 | -10.42 | 164.04 | 5.73 | |
| Ty-255 | 0.41 | -99.12 | -4.45 | -7.1 | 10.57 | 3.42 | -5.86 | -33.74 | -13.63 | -27.27 | -18.04 | 114.05 | -3.62 | |
| Ty-256 | -0.2 | -65.31 | -25.86 | -6.68 | -3.67 | -7.3 | 2.15 | -1.18 | -21.04 | -34.66 | -26.07 | 163 | 4.58 | |
| Ty-257 | 1.01 | 15.25 | 2.2 | -8.22 | 16.02 | -2.02 | 3.5 | -19.97 | -35.19 | -37.05 | 2.26 | 137.67 | -7.77 | |
| Ty-258 | -0.4 | 23.4 | -5.85 | -4.21 | 0.21 | -6.12 | -4.65 | -5.58 | -26.1 | -46.47 | -12.56 | 127.96 | -7.96 | |
| Ty-259 | 9.09 | 19.89 | 23.95 | 9.09 | 10.83 | -1.12 | 64.14 | 26.39 | 86.98 | -13.18 | 0.67 | 124.37 | 1.01 | |
| Ty-260 | 46.61 | 30.15 | 53.3 | -3.5 | 1.88 | -3.02 | 59.3 | 21.19 | 46.05 | -7.05 | -30.07 | 140.11 | 3.67 | |
| Ty-261 | 0.21 | -18.89 | 50.12 | 3.31 | 3.96 | -1.13 | 58.66 | 46.92 | 80.03 | 21.13 | -9.66 | 122.35 | -0.25 | |
| Ty-262 | -1 | 14.22 | 23.56 | 0.14 | 23 | -9.41 | 53.4 | -215.69 | -12.86 | -23.61 | -17.24 | 164.37 | 3.97 | |
| Ty-263 | -1.2 | -54.07 | -13.2 | 12.75 | 4.41 | -11.8 | 41.23 | -233.95 | 25.87 | -16.97 | -3.47 | 165.99 | -0.39 | |
| Ty-264 | 0.81 | 9.05 | 33.22 | 9.33 | -0.8 | -4.29 | 52.65 | -354.25 | 76.18 | -3.91 | -13.64 | 137.95 | -2.81 | |
| Ty-265 | 23.28 | -39.68 | 34.31 | 10.84 | 6.39 | 4.58 | 60.06 | -151.55 | 73.97 | -24.38 | -17.72 | 119.64 | 8.55 | |
| Ty-266 | -2.01 | 8.6 | 24.76 | 8.06 | 3.79 | -4.32 | 24.9 | -82.45 | 43.21 | -23.58 | -11.3 | 158.34 | -2.66 | |
| Ty-267 | -1 | 45.37 | -6.1 | 13.47 | 1.57 | 17.57 | 3.58 | -3.35 | -45.3 | -26.42 | -18.59 | 148.67 | -0.61 | |
| Ty-268 | 20.03 | -8.77 | -17.94 | 9.95 | -7.2 | 4.05 | 6.87 | -6.37 | -36.4 | -19.05 | -6.47 | 137.41 | -15.45 | |
| Ty-269 | -0.19 | 1.15 | 3.02 | -0.01 | -15.8 | -4.69 | 7.23 | -2.25 | -32.12 | -24.14 | -24.51 | 162.74 | -8.18 | |
| Ty-270 | -1.4 | 9.18 | -22.76 | -9.94 | 12.16 | -7.12 | 10.3 | -2.99 | -34.46 | -26.99 | -13.46 | 141.96 | -4.85 | |
| Ty-271 | -1.61 | -7.86 | -15.01 | -10.48 | -8.72 | 7.65 | 50.53 | 2.04 | -35.72 | -40.29 | -9.95 | 130.22 | 0.83 | |
| Ty-272 | 0.21 | 15.92 | 11.19 | -5.23 | 3.35 | 7.09 | 71.61 | 24.41 | -14.82 | -29.4 | 3.74 | 126.39 | -10.24 | |
| Ty-273 | 0 | 35.8 | 58.34 | -12.89 | -20.92 | -38.85 | 71.23 | 77.78 | 27.02 | -16.45 | -15.49 | 143.08 | -0.15 | |
| Ty-274 | -0.2 | 29.94 | -12.68 | -12.33 | 1.08 | -4.92 | 3.77 | -10.07 | -40.28 | -25.39 | -7.7 | 106.21 | -2.1 | |
| Ty-275 | 0.81 | 15.79 | -15.69 | -11.4 | -10.98 | 1.35 | -2.74 | -10.67 | -26.5 | -41.91 | -10.02 | 113.24 | 10.22 | |
| Ty-276 | 0.21 | 0.4 | -0.45 | 3.33 | 23.89 | -2.24 | 31.98 | -14.26 | -8.28 | -20.98 | -11.11 | 156.06 | 6.4 | |
| Ty-278 | 75.12 | -18.63 | 0.21 | -5 | 18.51 | -3.02 | 19.08 | -41.83 | -7.99 | -1.03 | 47.53 | 108.6 | 2.36 | |
| Ty-279 | 27.89 | 30.01 | 12.89 | -2.93 | 5.64 | -1.43 | 29.73 | -348.07 | -8.8 | -36 | -7.74 | 136.19 | -4 | |
| Ty-280 | 63.21 | 16.49 | 9.12 | 16.1 | -6.54 | -2.81 | 46.14 | -382.95 | -5.14 | -28.71 | -9.17 | 125.25 | 4.56 | |
| Ty-281 | 30.44 | 37.18 | 91.82 | 39.03 | 85.68 | -1.7 | 29.86 | -218.16 | 52.28 | -11.12 | 7.05 | 127.16 | -3.12 | |
| Ty-301 | 16.14 | -40.12 | 34.03 | 15.89 | 16.94 | 13.43 | 54.68 | -34.58 | 32.76 | 14.91 | 33.54 | 131.11 | -22.18 | |
| Ty-302 | -11.85 | -27.21 | 12.29 | -0.63 | 1.7 | 10.12 | 35.42 | -290.46 | 49.58 | 1.6 | 17.4 | 108.6 | -15.58 | |
| Ty-303 | -13.28 | -32.18 | 10.52 | -4.36 | 15.99 | 9.21 | 12.3 | -21.82 | 18.2 | 8.3 | -4.48 | 124.88 | -16.88 | |
| Ty-304 | -15.68 | -44.24 | 13.15 | 0.49 | 14.46 | 7.72 | -1.71 | -16.97 | 4.71 | 9.14 | -0.93 | 115.24 | -17.89 | |
| Ty-305 | -4.71 | -78.89 | 23.55 | -3.21 | -2.39 | 8.13 | 41.91 | 17.45 | 97.53 | 7.64 | 28.95 | 117.79 | 31.56 | |
| Ty-306 | 19.67 | -41.04 | 42.87 | -3.73 | -15.4 | 0.81 | 34.61 | 101.13 | 55.69 | -13.35 | 19.74 | 78.87 | 21.95 | |
| Ty-307 | 28.76 | -37.84 | 17.15 | -7.49 | 2.78 | -10.19 | 48.51 | -38.47 | 89.41 | 26.93 | 24.36 | 102.68 | -9.06 | |
| Ty-308 | 22 | 5.32 | 24.51 | -4.86 | -2.43 | -5.98 | 69.52 | -652.27 | 49.79 | 10.84 | 22.1 | 99.75 | -20.04 | |
| Ty-309 | 19.2 | -8.6 | 20.5 | -10.58 | -13.9 | 1.72 | 48.22 | -339.41 | 30.56 | 23.18 | 31.11 | 100.79 | -17.33 | |
| Ty-310 | 25.65 | -23.95 | 9.65 | -4.3 | 17.71 | -1.42 | 39.12 | -40.54 | 81.66 | 38.56 | 9.97 | 77.46 | -21.26 | |
| Ty-311 | -5.24 | -23.6 | 11.03 | 47.24 | 10 | -3.66 | 9.82 | -10.16 | 0.57 | 1.42 | 2.31 | 107.88 | -10.33 | |
| Ty-312 | 20.23 | 6.57 | 27 | -3.75 | 9.77 | 0.01 | 7.4 | -13.3 | -10.56 | -7.35 | 3.35 | 111.85 | -23.52 | |
| Ty-313 | 9.62 | 15.06 | 17.74 | 2.92 | 7.93 | -7.17 | 7.34 | 4.3 | 10.46 | 1.91 | -2.87 | 118 | -18.94 | |
| Ty-314 | 25.52 | 5.33 | 16.1 | 2.3 | 6.65 | 4.78 | 39.33 | 32.12 | 11.03 | 1.44 | 10.1 | 116.45 | -22.01 | |
| Ty-315 | 16.84 | 16.51 | 1.77 | 7.74 | -11.86 | 4.91 | 33.95 | 18.02 | 6.68 | 5.51 | -8.68 | 123.65 | -18.54 | |
| Ty-316 | 14.58 | 14.81 | 15.17 | 23.43 | -3.37 | 3.01 | 21.39 | 1.66 | 98.03 | 11 | 13.83 | 119.07 | -27.78 | |
| Ty-317 | 3.13 | 26.29 | 15.68 | 10.25 | -2.93 | 3.5 | 32.11 | 26.53 | 18.32 | 23.52 | -2.9 | 125.02 | -16.41 | |
| Ty-319 | 8.63 | 20.65 | 16.9 | 6.4 | -2.63 | 8.98 | 49.04 | 55.63 | 58.03 | 22.63 | 14.13 | 125.12 | -26.1 | |
| Ty-320 | 22.81 | 6.84 | 7.8 | 16.91 | 11.54 | 10.35 | 12.19 | 27.89 | 108.58 | 11.05 | 33.84 | 125.08 | -14.63 | |
| Ty-321 | 21.75 | -19.04 | 17.55 | -1.38 | -17.31 | 5.34 | 49.63 | 51.37 | 65.19 | 16.96 | 15.13 | 126.91 | -15.61 | |
| Ty-322 | 83.59 | -24.08 | 15.75 | 34.49 | -4.47 | 17.84 | 31.38 | 49.66 | 110.32 | 20.96 | 32.64 | 100.06 | 4.75 | |
| Ty-323 | 11.66 | -72.65 | 17.88 | -6.83 | -26.03 | 2.23 | 41.99 | 95.74 | 73.93 | 17.16 | 24.12 | 85.35 | 11.24 | |
| Ty-324 | 20.25 | -31.74 | 50.88 | 1.22 | 12.76 | -2.99 | 89.88 | 102.06 | 61.65 | 100.78 | 99.67 | 96.1 | -17.01 | |
| Ty-325 | 18.34 | -16.03 | 17.19 | -1.54 | 14.05 | -11.41 | 24.05 | 19.16 | 14.64 | 14.17 | 19.62 | 111.64 | -14.49 | |
| Ty-326 | 26.86 | -10.08 | 18.38 | 0.46 | -0.52 | -11.91 | 57.57 | 9.23 | 72.67 | 21.3 | 31.17 | 102.92 | -13.74 | |
| Ty-327 | 34.16 | -49.61 | -1.81 | -2.2 | 13.88 | 1.97 | 63.71 | 9.97 | 46.18 | 29.05 | 21.23 | 108.11 | -11.91 | |
| Ty-328 | 47.77 | -14.54 | 12.02 | -10.75 | -7.32 | -9.56 | 61.26 | 66.01 | 31.93 | 15.99 | 26.75 | 130.57 | -10.04 | |
| Ty-330 | 51.36 | -5.21 | 16.39 | 7.27 | -5.42 | -10.09 | 71.99 | 63.92 | 23.06 | 14.6 | 33.26 | 112.64 | -23.49 | |
| Ty-331 | 30.23 | -14.45 | 3.2 | 20.31 | 0.84 | -5.04 | 63.65 | 60.1 | 19.58 | 10.15 | 11.1 | 125.8 | -12.44 | |
| Ty-332 | 32.41 | 7.29 | -1.04 | 1.43 | 21.59 | 1.87 | 45.44 | 10.66 | 86.87 | 14.98 | 12.09 | 123.31 | -16 | |
| Ty-333 | 17.74 | -27.44 | 11.03 | 19.11 | -11.59 | 18.07 | 41.91 | 43.19 | 93.58 | 20.16 | 33.84 | 125.87 | -20.06 | |
| Ty-334 | 97.61 | -13.32 | 7.87 | 0.6 | -36.9 | -1.19 | 65.16 | 78.6 | 63.41 | 16.27 | 25.18 | 120.76 | -23.59 | |
| Ty-335 | 39.85 | -32.59 | 15.27 | 5.5 | 5.16 | 4.88 | 58.59 | 74.5 | 30.08 | 7.7 | 34.36 | 118.64 | -12.58 | |
| Ty-336 | 35.31 | -14.54 | 6.51 | 13.12 | -20.48 | 13.72 | 23.66 | 22.89 | 103.27 | 9.43 | 32.72 | 108.33 | -15.61 | |
| Ty-337 | 19.41 | 3.38 | 25.4 | 19.06 | 5.31 | 33.36 | 20.16 | 32.68 | 102.77 | 7.9 | 21.02 | 115 | -16.4 | |
| Ty-338 | 23.57 | -41.44 | 10.16 | -5.69 | -19.05 | 4.36 | 35.96 | 100.86 | 77.08 | 9.85 | 23.31 | 126.01 | -19.4 | |
| Ty-339 | 8.03 | -48.33 | 18.57 | -12.36 | 2.64 | 1.4 | 51.4 | 13.11 | 98.73 | 19.64 | 2.8 | 123.48 | 4.34 | |
| Ty-340 | 19.32 | -55.95 | 40.46 | -13.59 | -0.22 | -1.73 | 86.84 | 20.1 | 77.05 | 7.87 | 15.11 | 65.76 | 29.81 | |
| Ty-341 | 36.13 | -20.88 | 4.62 | -14.42 | -3.95 | 1.85 | 80.89 | 34.53 | 78.62 | 14.49 | 14 | 80.2 | -9.62 | |
| Ty-342 | 99.86 | 40.38 | 48.82 | 9.51 | 14.24 | 5.19 | 23.73 | 91.42 | 106.83 | 34.26 | 65.66 | 102.03 | -12.17 | |
| Ty-343 | 36.97 | -2.62 | 6.65 | -13.49 | -10.74 | -3.94 | 53.94 | 28.28 | 107.48 | 21.05 | 19.21 | 93.41 | -17.76 | |
| Ty-344 | 36.67 | 1.8 | 22.5 | -0.6 | -5.15 | -14.98 | 22.61 | 19.31 | -10.4 | 12.94 | 12.99 | 90.39 | -10.9 | |
| Ty-346 | 31.15 | 29.96 | 16.36 | 5.11 | 2.51 | -5.33 | 20.18 | 54.03 | 26.11 | 15.34 | 38.29 | 114.61 | -13.08 | |
| Ty-347 | 31.3 | 23.8 | 31.65 | 18.13 | 4.01 | 10.31 | 22.69 | 53.39 | 11.56 | 19.85 | 49.14 | 120.82 | -15.89 | |
| Ty-348 | 96.91 | 43.44 | 48.07 | 16.47 | 5.8 | 21.95 | 29.46 | 86.01 | 97.85 | 16.41 | 81.18 | 80.73 | -17.56 | |
| Ty-349 | 93.28 | 46.15 | 37.27 | 20.97 | 14.5 | 2.39 | 58.72 | 13.63 | 58.98 | 18.5 | 57.54 | 113.76 | -14.35 | |
| Ty-350 | 98.02 | 61.45 | 59.48 | 39.88 | -10.61 | 7.79 | 45.86 | 84.58 | 71.62 | 18.36 | 72.94 | 116.65 | -12.46 | |
| Ty-351 | 98.04 | 32.06 | 62.39 | 12.93 | 10.19 | 0.63 | 72.5 | 71.54 | 86.61 | 20.12 | 62.67 | 115.96 | -12.35 | |
| Ty-352 | 97.45 | 56.67 | 72.05 | 3.41 | -9.13 | -4.36 | 27.05 | 59.85 | 87.22 | 16.47 | 77.57 | 123.52 | -23.63 |
